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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AKAP1-C17orf67 (FusionGDB2 ID:3333)

Fusion Gene Summary for AKAP1-C17orf67

check button Fusion gene summary
Fusion gene informationFusion gene name: AKAP1-C17orf67
Fusion gene ID: 3333
HgeneTgene
Gene symbol

AKAP1

C17orf67

Gene ID

8165

339210

Gene nameA-kinase anchoring protein 1chromosome 17 open reading frame 67
SynonymsAKAP|AKAP121|AKAP149|AKAP84|D-AKAP1|PPP1R43|PRKA1|SAKAP84|TDRD17-
Cytomap

17q22

17q22

Type of geneprotein-codingprotein-coding
DescriptionA-kinase anchor protein 1, mitochondrialA kinase (PRKA) anchor protein 1A-kinase anchor protein 149 kDaAKAP 149D-AKAP-1dual-specificity A-kinase anchoring protein 1protein kinase A anchoring protein 1protein kinase A1protein phosphatase 1, regulatuncharacterized protein C17orf67
Modification date2020031320200313
UniProtAcc

Q92667

Q0P5P2

Ensembl transtripts involved in fusion geneENST00000314126, ENST00000337714, 
ENST00000539273, ENST00000571629, 
ENST00000572557, 		ENST00000397861, 
ENST00000575658, ENST00000397862, 
ENST00000487705, 
Fusion gene scores* DoF score10 X 8 X 4=3204 X 6 X 3=72
# samples 125
** MAII scorelog2(12/320*10)=-1.41503749927884
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/72*10)=-0.526068811667588
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AKAP1 [Title/Abstract] AND C17orf67 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAKAP1(55184539)-C17orf67(54893419), # samples:2
AKAP1(55184539)-C17orf67(54893371), # samples:2
Anticipated loss of major functional domain due to fusion event.AKAP1-C17orf67 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across AKAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across C17orf67 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E2-A15H-01AAKAP1chr17

55184539

+C17orf67chr17

54872541

-
ChimerDB4BRCATCGA-E2-A15H-01AAKAP1chr17

55184539

-C17orf67chr17

54893371

-
ChimerDB4BRCATCGA-E2-A15H-01AAKAP1chr17

55184539

+C17orf67chr17

54893371

-
ChimerDB4BRCATCGA-E2-A15H-01AAKAP1chr17

55184539

+C17orf67chr17

54893419

-


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Fusion Gene ORF analysis for AKAP1-C17orf67

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000314126ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-5UTRENST00000314126ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-5UTRENST00000337714ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-5UTRENST00000337714ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-5UTRENST00000539273ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-5UTRENST00000539273ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-5UTRENST00000571629ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-5UTRENST00000571629ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-5UTRENST00000572557ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-5UTRENST00000572557ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-intronENST00000314126ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000314126ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-intronENST00000314126ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000314126ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54872541

-
5CDS-intronENST00000314126ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-intronENST00000314126ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000314126ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000337714ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000337714ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-intronENST00000337714ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000337714ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54872541

-
5CDS-intronENST00000337714ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-intronENST00000337714ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000337714ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000539273ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000539273ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-intronENST00000539273ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000539273ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54872541

-
5CDS-intronENST00000539273ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-intronENST00000539273ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000539273ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000571629ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000571629ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-intronENST00000571629ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000571629ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54872541

-
5CDS-intronENST00000571629ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-intronENST00000571629ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000571629ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000572557ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000572557ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-intronENST00000572557ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000572557ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54872541

-
5CDS-intronENST00000572557ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54893371

-
5CDS-intronENST00000572557ENST00000487705AKAP1chr17

55184539

+C17orf67chr17

54893419

-
5CDS-intronENST00000572557ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54893419

-
Frame-shiftENST00000314126ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54872541

-
Frame-shiftENST00000337714ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54872541

-
Frame-shiftENST00000539273ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54872541

-
Frame-shiftENST00000571629ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54872541

-
Frame-shiftENST00000572557ENST00000397862AKAP1chr17

55184539

+C17orf67chr17

54872541

-
In-frameENST00000314126ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54872541

-
In-frameENST00000314126ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54872541

-
In-frameENST00000337714ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54872541

-
In-frameENST00000337714ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54872541

-
In-frameENST00000539273ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54872541

-
In-frameENST00000539273ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54872541

-
In-frameENST00000571629ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54872541

-
In-frameENST00000571629ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54872541

-
In-frameENST00000572557ENST00000397861AKAP1chr17

55184539

+C17orf67chr17

54872541

-
In-frameENST00000572557ENST00000575658AKAP1chr17

55184539

+C17orf67chr17

54872541

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000337714AKAP1chr1755184539+ENST00000397861C17orf67chr1754872541-252419472331987584
ENST00000337714AKAP1chr1755184539+ENST00000575658C17orf67chr1754872541-252319472331987584
ENST00000314126AKAP1chr1755184539+ENST00000397861C17orf67chr1754872541-252219452311985584
ENST00000314126AKAP1chr1755184539+ENST00000575658C17orf67chr1754872541-252119452311985584
ENST00000571629AKAP1chr1755184539+ENST00000397861C17orf67chr1754872541-263320563422096584
ENST00000571629AKAP1chr1755184539+ENST00000575658C17orf67chr1754872541-263220563422096584
ENST00000572557AKAP1chr1755184539+ENST00000397861C17orf67chr1754872541-243118541401894584
ENST00000572557AKAP1chr1755184539+ENST00000575658C17orf67chr1754872541-243018541401894584
ENST00000539273AKAP1chr1755184539+ENST00000397861C17orf67chr1754872541-250119242101964584
ENST00000539273AKAP1chr1755184539+ENST00000575658C17orf67chr1754872541-250019242101964584

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000337714ENST00000397861AKAP1chr1755184539+C17orf67chr1754872541-0.011449930.9885501
ENST00000337714ENST00000575658AKAP1chr1755184539+C17orf67chr1754872541-0.0116564540.9883435
ENST00000314126ENST00000397861AKAP1chr1755184539+C17orf67chr1754872541-0.0112889260.98871106
ENST00000314126ENST00000575658AKAP1chr1755184539+C17orf67chr1754872541-0.0114915730.9885084
ENST00000571629ENST00000397861AKAP1chr1755184539+C17orf67chr1754872541-0.0087333180.99126667
ENST00000571629ENST00000575658AKAP1chr1755184539+C17orf67chr1754872541-0.0089141890.9910858
ENST00000572557ENST00000397861AKAP1chr1755184539+C17orf67chr1754872541-0.0112124210.9887876
ENST00000572557ENST00000575658AKAP1chr1755184539+C17orf67chr1754872541-0.0114329250.9885671
ENST00000539273ENST00000397861AKAP1chr1755184539+C17orf67chr1754872541-0.0127925970.98720735
ENST00000539273ENST00000575658AKAP1chr1755184539+C17orf67chr1754872541-0.0130369240.9869631

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Fusion Genomic Features for AKAP1-C17orf67


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for AKAP1-C17orf67


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:55184539/chr17:54893419)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AKAP1

Q92667

C17orf67

Q0P5P2

FUNCTION: Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane (By similarity). Involved in mitochondrial-mediated antiviral innate immunity (PubMed:31522117). Promotes translocation of NDUFS1 into mitochondria to regulate mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) activity (By similarity). {ECO:0000250|UniProtKB:O08715, ECO:0000269|PubMed:31522117}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAKAP1chr17:55184539chr17:54872541ENST00000314126+23344_357571594.0RegionNote=PKA-RII subunit binding domain
HgeneAKAP1chr17:55184539chr17:54872541ENST00000337714+211344_357571904.0RegionNote=PKA-RII subunit binding domain
HgeneAKAP1chr17:55184539chr17:54872541ENST00000539273+211344_357571904.0RegionNote=PKA-RII subunit binding domain
HgeneAKAP1chr17:55184539chr17:54872541ENST00000571629+312344_357571904.0RegionNote=PKA-RII subunit binding domain
HgeneAKAP1chr17:55184539chr17:54872541ENST00000572557+211344_357571904.0RegionNote=PKA-RII subunit binding domain

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAKAP1chr17:55184539chr17:54872541ENST00000314126+23607_671571594.0DomainKH
HgeneAKAP1chr17:55184539chr17:54872541ENST00000314126+23758_817571594.0DomainTudor
HgeneAKAP1chr17:55184539chr17:54872541ENST00000337714+211607_671571904.0DomainKH
HgeneAKAP1chr17:55184539chr17:54872541ENST00000337714+211758_817571904.0DomainTudor
HgeneAKAP1chr17:55184539chr17:54872541ENST00000539273+211607_671571904.0DomainKH
HgeneAKAP1chr17:55184539chr17:54872541ENST00000539273+211758_817571904.0DomainTudor
HgeneAKAP1chr17:55184539chr17:54872541ENST00000571629+312607_671571904.0DomainKH
HgeneAKAP1chr17:55184539chr17:54872541ENST00000571629+312758_817571904.0DomainTudor
HgeneAKAP1chr17:55184539chr17:54872541ENST00000572557+211607_671571904.0DomainKH
HgeneAKAP1chr17:55184539chr17:54872541ENST00000572557+211758_817571904.0DomainTudor


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Fusion Gene Sequence for AKAP1-C17orf67


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>3333_3333_1_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000314126_C17orf67_chr17_54872541_ENST00000397861_length(transcript)=2522nt_BP=1945nt
AAGGGCGAGGGGCGGGGCCTGCGTCGCGCTGCGGGCACGTCGCCGCGCGTCTTCAGTATTTAATGTCTCTGTGTTCCACCCGCCTGGGCT
AGCACGTGGGGGAGCTGCGGAAGCGCGGCGCTGCGGGCCGGGCCGCGGGGCACAGCCGGGGGCCGGCGGCGGCGCGCGGACTCCGCATCC
CGCACCCCGATGGTAGCCGAGGAGCTGGTGTAATTACTTCAAGCCTCCAGGATGGCAATCCAGTTCCGTTCGCTCTTCCCCTTGGCATTG
CCTGGGATGCTGGCGCTCCTCGGCTGGTGGTGGTTTTTCTCTCGTAAAAAAGGCCATGTCAGCAGCCATGATGAGCAGCAGGTGGAGGCT
GGTGCTGTGCAGCTGAGGGCTGACCCTGCCATCAAGGAACCTCTCCCCGTGGAAGACGTCTGTCCCAAAGTAGTGTCCACACCCCCCAGT
GTCACAGAGCCTCCAGAAAAGGAACTGTCCACCGTGAGCAAGCTGCCTGCAGAGCCCCCAGCATTGCTCCAGACACACCCACCTTGCCGA
AGATCAGAGTCCTCGGGCATTCTTCCTAACACCACAGACATGAGATTGCGACCAGGAACACGCAGAGATGACAGTACAAAGCTGGAGCTA
GCCCTGACAGGTGGTGAAGCCAAATCGATTCCTCTAGAGTGCCCCCTTTCATCCCCAAAGGGTGTACTATTCTCCAGCAAATCAGCTGAG
GTGTGTAAGCAAGATTCCCCCTTCAGCAGGGTGCCAAGGAAGGTCCAGCCAGGCTACCCCGTAGTCCCCGCAGAGAAGCGTAGCTCTGGG
GAGAGGGCAAGAGAGACAGGTGGGGCCGAAGGGACTGGTGATGCCGTGTTGGGGGAAAAGGTGCTTGAAGAAGCTCTGTTGTCTCGGGAG
CATGTCTTGGAATTGGAGAACAGCAAGGGCCCCAGCCTGGCCTCTTTAGAGGGGGAAGAAGATAAGGGGAAGAGCAGCTCATCCCAGGTG
GTGGGGCCAGTGCAGGAGGAAGAGTATGTAGCAGAGAAGTTGCCAAGTAGGTTCATCGAGTCGGCTCACACAGAGCTGGCAAAGGACGAT
GCGGCGCCAGCACCCCCAGTCGCAGACGCCAAAGCCCAGGATAGAGGTGTCGAGGGAGAACTGGGCAATGAGGAGAGCTTGGATAGAAAT
GAGGAGGGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAG
ATTAAGCGGGCTGCCTTCCAGATAATCTCCCAAGTGATCTCAGAAGCAACCGAACAGGTGCTGGCCACCACGGTTGGCAAGGTTGCAGGT
CGTGTGTGTCAGGCCAGTCAGCTCCAAGGGCAGAAGGAAGAGAGCTGTGTCCCAGTTCACCAGAAAACTGTCTTGGGCCCAGACACTGCG
GAGCCTGCCACAGCAGAGGCAGCTGTTGCCCCGCCGGATGCTGGCCTCCCCTTGCCAGGCCTACCAGCAGAGGGCTCACCACCACCAAAG
ACCTACGTGAGCTGCCTGAAGAGCCTTCTGTCCAGCCCCACCAAGGACAGTAAGCCAAATATCTCTGCACACCACATCTCCCTGGCCTCC
TGCCTGGCACTGACCACCCCCAGTGAAGAGTTGCCGGACCGGGCAGGCATCCTGGTGGAAGATGCCACCTGTGTCACCTGCATGTCAGAC
AGCAGCCAAAGTGTCCCTTTGGTGGCTTCTCCAGGACACTGCTCAGATTCTTTCAGCACTTCAGGGCTTGAAGACTCTTGCACAGAGACC
AGCTCGAGCCCCAGGGACAAGGCCATCACCCCGCCACTGCCAGAAAGTACTGTGCCCTTCAGCAATGGGGTGCTGAAGGGGGAGTTGTCA
GACTTGGGGGCTGAGGATGGATGGACCATGGATGCGGAAGCAGATCATTCAGGAGGAATACATGCACCACCTGCTCGCCCTGGAGCATCG
CGCTGAGGAGCAGTTCCTGGAGCACTGGCTGAACCCTCACTGCAAACCCCACTGTGACAGGAACAGGATTCATCCTGTGTAAGGGGATCA
GGACCAGCCTCGCAAGCATTTTAATAGACAACAAGCTGGATAATGTCGAAGCAAGACAAGGCTGCTTCTTTCACTTGTTTTTAAATTGCA
GAAATGGATGTCTTCAGACCTCGTGAACTGTGGGCATATCAAAGATTGCCTTGGAAATGGCAAATATATATACTGCTTCATTTTACTAAC
CTGCATAGATCACTAAAACCAATAGCTTAAAGCATAGACACCTCCCAAAGGTCTTCCCATCAGTTTGCAAGAGTGGGAACAACCAGAATC
TTACCTGGGGTTGATGGAGCTGGAACTCCCAGACCAGGAGTTGGGGCAGGCTGCCTGCCCTAAGGAATTTGGGGAATCCTTGTTCAGAGT
AGTGAAGCATACCACTTGGGGTTGCTGAGTTGTTTTGTCCTCTATTTTTTTCCTCTTCTTTTCTGCCCTAATAAACATTGGTATTAAATT

>3333_3333_1_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000314126_C17orf67_chr17_54872541_ENST00000397861_length(amino acids)=584AA_BP=
MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKELSTVSKLPA
EPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQP
GYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSR
FIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEAT
EQVLATTVGKVAGRVCQASQLQGQKEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDS
KPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPEST

--------------------------------------------------------------
>3333_3333_2_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000314126_C17orf67_chr17_54872541_ENST00000575658_length(transcript)=2521nt_BP=1945nt
AAGGGCGAGGGGCGGGGCCTGCGTCGCGCTGCGGGCACGTCGCCGCGCGTCTTCAGTATTTAATGTCTCTGTGTTCCACCCGCCTGGGCT
AGCACGTGGGGGAGCTGCGGAAGCGCGGCGCTGCGGGCCGGGCCGCGGGGCACAGCCGGGGGCCGGCGGCGGCGCGCGGACTCCGCATCC
CGCACCCCGATGGTAGCCGAGGAGCTGGTGTAATTACTTCAAGCCTCCAGGATGGCAATCCAGTTCCGTTCGCTCTTCCCCTTGGCATTG
CCTGGGATGCTGGCGCTCCTCGGCTGGTGGTGGTTTTTCTCTCGTAAAAAAGGCCATGTCAGCAGCCATGATGAGCAGCAGGTGGAGGCT
GGTGCTGTGCAGCTGAGGGCTGACCCTGCCATCAAGGAACCTCTCCCCGTGGAAGACGTCTGTCCCAAAGTAGTGTCCACACCCCCCAGT
GTCACAGAGCCTCCAGAAAAGGAACTGTCCACCGTGAGCAAGCTGCCTGCAGAGCCCCCAGCATTGCTCCAGACACACCCACCTTGCCGA
AGATCAGAGTCCTCGGGCATTCTTCCTAACACCACAGACATGAGATTGCGACCAGGAACACGCAGAGATGACAGTACAAAGCTGGAGCTA
GCCCTGACAGGTGGTGAAGCCAAATCGATTCCTCTAGAGTGCCCCCTTTCATCCCCAAAGGGTGTACTATTCTCCAGCAAATCAGCTGAG
GTGTGTAAGCAAGATTCCCCCTTCAGCAGGGTGCCAAGGAAGGTCCAGCCAGGCTACCCCGTAGTCCCCGCAGAGAAGCGTAGCTCTGGG
GAGAGGGCAAGAGAGACAGGTGGGGCCGAAGGGACTGGTGATGCCGTGTTGGGGGAAAAGGTGCTTGAAGAAGCTCTGTTGTCTCGGGAG
CATGTCTTGGAATTGGAGAACAGCAAGGGCCCCAGCCTGGCCTCTTTAGAGGGGGAAGAAGATAAGGGGAAGAGCAGCTCATCCCAGGTG
GTGGGGCCAGTGCAGGAGGAAGAGTATGTAGCAGAGAAGTTGCCAAGTAGGTTCATCGAGTCGGCTCACACAGAGCTGGCAAAGGACGAT
GCGGCGCCAGCACCCCCAGTCGCAGACGCCAAAGCCCAGGATAGAGGTGTCGAGGGAGAACTGGGCAATGAGGAGAGCTTGGATAGAAAT
GAGGAGGGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAG
ATTAAGCGGGCTGCCTTCCAGATAATCTCCCAAGTGATCTCAGAAGCAACCGAACAGGTGCTGGCCACCACGGTTGGCAAGGTTGCAGGT
CGTGTGTGTCAGGCCAGTCAGCTCCAAGGGCAGAAGGAAGAGAGCTGTGTCCCAGTTCACCAGAAAACTGTCTTGGGCCCAGACACTGCG
GAGCCTGCCACAGCAGAGGCAGCTGTTGCCCCGCCGGATGCTGGCCTCCCCTTGCCAGGCCTACCAGCAGAGGGCTCACCACCACCAAAG
ACCTACGTGAGCTGCCTGAAGAGCCTTCTGTCCAGCCCCACCAAGGACAGTAAGCCAAATATCTCTGCACACCACATCTCCCTGGCCTCC
TGCCTGGCACTGACCACCCCCAGTGAAGAGTTGCCGGACCGGGCAGGCATCCTGGTGGAAGATGCCACCTGTGTCACCTGCATGTCAGAC
AGCAGCCAAAGTGTCCCTTTGGTGGCTTCTCCAGGACACTGCTCAGATTCTTTCAGCACTTCAGGGCTTGAAGACTCTTGCACAGAGACC
AGCTCGAGCCCCAGGGACAAGGCCATCACCCCGCCACTGCCAGAAAGTACTGTGCCCTTCAGCAATGGGGTGCTGAAGGGGGAGTTGTCA
GACTTGGGGGCTGAGGATGGATGGACCATGGATGCGGAAGCAGATCATTCAGGAGGAATACATGCACCACCTGCTCGCCCTGGAGCATCG
CGCTGAGGAGCAGTTCCTGGAGCACTGGCTGAACCCTCACTGCAAACCCCACTGTGACAGGAACAGGATTCATCCTGTGTAAGGGGATCA
GGACCAGCCTCGCAAGCATTTTAATAGACAACAAGCTGGATAATGTCGAAGCAAGACAAGGCTGCTTCTTTCACTTGTTTTTAAATTGCA
GAAATGGATGTCTTCAGACCTCGTGAACTGTGGGCATATCAAAGATTGCCTTGGAAATGGCAAATATATATACTGCTTCATTTTACTAAC
CTGCATAGATCACTAAAACCAATAGCTTAAAGCATAGACACCTCCCAAAGGTCTTCCCATCAGTTTGCAAGAGTGGGAACAACCAGAATC
TTACCTGGGGTTGATGGAGCTGGAACTCCCAGACCAGGAGTTGGGGCAGGCTGCCTGCCCTAAGGAATTTGGGGAATCCTTGTTCAGAGT
AGTGAAGCATACCACTTGGGGTTGCTGAGTTGTTTTGTCCTCTATTTTTTTCCTCTTCTTTTCTGCCCTAATAAACATTGGTATTAAATT

>3333_3333_2_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000314126_C17orf67_chr17_54872541_ENST00000575658_length(amino acids)=584AA_BP=
MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKELSTVSKLPA
EPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQP
GYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSR
FIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEAT
EQVLATTVGKVAGRVCQASQLQGQKEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDS
KPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPEST

--------------------------------------------------------------
>3333_3333_3_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000337714_C17orf67_chr17_54872541_ENST00000397861_length(transcript)=2524nt_BP=1947nt
ACAAGGGCGAGGGGCGGGGCCTGCGTCGCGCTGCGGGCACGTCGCCGCGCGTCTTCAGTATTTAATGTCTCTGTGTTCCACCCGCCTGGG
CTAGCACGTGGGGGAGCTGCGGAAGCGCGGCGCTGCGGGCCGGGCCGCGGGGCACAGCCGGGGGCCGGCGGCGGCGCGCGGACTCCGCAT
CCCGCACCCCGATGGTAGCCGAGGAGCTGGTGTAATTACTTCAAGCCTCCAGGATGGCAATCCAGTTCCGTTCGCTCTTCCCCTTGGCAT
TGCCTGGGATGCTGGCGCTCCTCGGCTGGTGGTGGTTTTTCTCTCGTAAAAAAGGCCATGTCAGCAGCCATGATGAGCAGCAGGTGGAGG
CTGGTGCTGTGCAGCTGAGGGCTGACCCTGCCATCAAGGAACCTCTCCCCGTGGAAGACGTCTGTCCCAAAGTAGTGTCCACACCCCCCA
GTGTCACAGAGCCTCCAGAAAAGGAACTGTCCACCGTGAGCAAGCTGCCTGCAGAGCCCCCAGCATTGCTCCAGACACACCCACCTTGCC
GAAGATCAGAGTCCTCGGGCATTCTTCCTAACACCACAGACATGAGATTGCGACCAGGAACACGCAGAGATGACAGTACAAAGCTGGAGC
TAGCCCTGACAGGTGGTGAAGCCAAATCGATTCCTCTAGAGTGCCCCCTTTCATCCCCAAAGGGTGTACTATTCTCCAGCAAATCAGCTG
AGGTGTGTAAGCAAGATTCCCCCTTCAGCAGGGTGCCAAGGAAGGTCCAGCCAGGCTACCCCGTAGTCCCCGCAGAGAAGCGTAGCTCTG
GGGAGAGGGCAAGAGAGACAGGTGGGGCCGAAGGGACTGGTGATGCCGTGTTGGGGGAAAAGGTGCTTGAAGAAGCTCTGTTGTCTCGGG
AGCATGTCTTGGAATTGGAGAACAGCAAGGGCCCCAGCCTGGCCTCTTTAGAGGGGGAAGAAGATAAGGGGAAGAGCAGCTCATCCCAGG
TGGTGGGGCCAGTGCAGGAGGAAGAGTATGTAGCAGAGAAGTTGCCAAGTAGGTTCATCGAGTCGGCTCACACAGAGCTGGCAAAGGACG
ATGCGGCGCCAGCACCCCCAGTCGCAGACGCCAAAGCCCAGGATAGAGGTGTCGAGGGAGAACTGGGCAATGAGGAGAGCTTGGATAGAA
ATGAGGAGGGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGG
AGATTAAGCGGGCTGCCTTCCAGATAATCTCCCAAGTGATCTCAGAAGCAACCGAACAGGTGCTGGCCACCACGGTTGGCAAGGTTGCAG
GTCGTGTGTGTCAGGCCAGTCAGCTCCAAGGGCAGAAGGAAGAGAGCTGTGTCCCAGTTCACCAGAAAACTGTCTTGGGCCCAGACACTG
CGGAGCCTGCCACAGCAGAGGCAGCTGTTGCCCCGCCGGATGCTGGCCTCCCCTTGCCAGGCCTACCAGCAGAGGGCTCACCACCACCAA
AGACCTACGTGAGCTGCCTGAAGAGCCTTCTGTCCAGCCCCACCAAGGACAGTAAGCCAAATATCTCTGCACACCACATCTCCCTGGCCT
CCTGCCTGGCACTGACCACCCCCAGTGAAGAGTTGCCGGACCGGGCAGGCATCCTGGTGGAAGATGCCACCTGTGTCACCTGCATGTCAG
ACAGCAGCCAAAGTGTCCCTTTGGTGGCTTCTCCAGGACACTGCTCAGATTCTTTCAGCACTTCAGGGCTTGAAGACTCTTGCACAGAGA
CCAGCTCGAGCCCCAGGGACAAGGCCATCACCCCGCCACTGCCAGAAAGTACTGTGCCCTTCAGCAATGGGGTGCTGAAGGGGGAGTTGT
CAGACTTGGGGGCTGAGGATGGATGGACCATGGATGCGGAAGCAGATCATTCAGGAGGAATACATGCACCACCTGCTCGCCCTGGAGCAT
CGCGCTGAGGAGCAGTTCCTGGAGCACTGGCTGAACCCTCACTGCAAACCCCACTGTGACAGGAACAGGATTCATCCTGTGTAAGGGGAT
CAGGACCAGCCTCGCAAGCATTTTAATAGACAACAAGCTGGATAATGTCGAAGCAAGACAAGGCTGCTTCTTTCACTTGTTTTTAAATTG
CAGAAATGGATGTCTTCAGACCTCGTGAACTGTGGGCATATCAAAGATTGCCTTGGAAATGGCAAATATATATACTGCTTCATTTTACTA
ACCTGCATAGATCACTAAAACCAATAGCTTAAAGCATAGACACCTCCCAAAGGTCTTCCCATCAGTTTGCAAGAGTGGGAACAACCAGAA
TCTTACCTGGGGTTGATGGAGCTGGAACTCCCAGACCAGGAGTTGGGGCAGGCTGCCTGCCCTAAGGAATTTGGGGAATCCTTGTTCAGA
GTAGTGAAGCATACCACTTGGGGTTGCTGAGTTGTTTTGTCCTCTATTTTTTTCCTCTTCTTTTCTGCCCTAATAAACATTGGTATTAAA

>3333_3333_3_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000337714_C17orf67_chr17_54872541_ENST00000397861_length(amino acids)=584AA_BP=
MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKELSTVSKLPA
EPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQP
GYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSR
FIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEAT
EQVLATTVGKVAGRVCQASQLQGQKEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDS
KPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPEST

--------------------------------------------------------------
>3333_3333_4_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000337714_C17orf67_chr17_54872541_ENST00000575658_length(transcript)=2523nt_BP=1947nt
ACAAGGGCGAGGGGCGGGGCCTGCGTCGCGCTGCGGGCACGTCGCCGCGCGTCTTCAGTATTTAATGTCTCTGTGTTCCACCCGCCTGGG
CTAGCACGTGGGGGAGCTGCGGAAGCGCGGCGCTGCGGGCCGGGCCGCGGGGCACAGCCGGGGGCCGGCGGCGGCGCGCGGACTCCGCAT
CCCGCACCCCGATGGTAGCCGAGGAGCTGGTGTAATTACTTCAAGCCTCCAGGATGGCAATCCAGTTCCGTTCGCTCTTCCCCTTGGCAT
TGCCTGGGATGCTGGCGCTCCTCGGCTGGTGGTGGTTTTTCTCTCGTAAAAAAGGCCATGTCAGCAGCCATGATGAGCAGCAGGTGGAGG
CTGGTGCTGTGCAGCTGAGGGCTGACCCTGCCATCAAGGAACCTCTCCCCGTGGAAGACGTCTGTCCCAAAGTAGTGTCCACACCCCCCA
GTGTCACAGAGCCTCCAGAAAAGGAACTGTCCACCGTGAGCAAGCTGCCTGCAGAGCCCCCAGCATTGCTCCAGACACACCCACCTTGCC
GAAGATCAGAGTCCTCGGGCATTCTTCCTAACACCACAGACATGAGATTGCGACCAGGAACACGCAGAGATGACAGTACAAAGCTGGAGC
TAGCCCTGACAGGTGGTGAAGCCAAATCGATTCCTCTAGAGTGCCCCCTTTCATCCCCAAAGGGTGTACTATTCTCCAGCAAATCAGCTG
AGGTGTGTAAGCAAGATTCCCCCTTCAGCAGGGTGCCAAGGAAGGTCCAGCCAGGCTACCCCGTAGTCCCCGCAGAGAAGCGTAGCTCTG
GGGAGAGGGCAAGAGAGACAGGTGGGGCCGAAGGGACTGGTGATGCCGTGTTGGGGGAAAAGGTGCTTGAAGAAGCTCTGTTGTCTCGGG
AGCATGTCTTGGAATTGGAGAACAGCAAGGGCCCCAGCCTGGCCTCTTTAGAGGGGGAAGAAGATAAGGGGAAGAGCAGCTCATCCCAGG
TGGTGGGGCCAGTGCAGGAGGAAGAGTATGTAGCAGAGAAGTTGCCAAGTAGGTTCATCGAGTCGGCTCACACAGAGCTGGCAAAGGACG
ATGCGGCGCCAGCACCCCCAGTCGCAGACGCCAAAGCCCAGGATAGAGGTGTCGAGGGAGAACTGGGCAATGAGGAGAGCTTGGATAGAA
ATGAGGAGGGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGG
AGATTAAGCGGGCTGCCTTCCAGATAATCTCCCAAGTGATCTCAGAAGCAACCGAACAGGTGCTGGCCACCACGGTTGGCAAGGTTGCAG
GTCGTGTGTGTCAGGCCAGTCAGCTCCAAGGGCAGAAGGAAGAGAGCTGTGTCCCAGTTCACCAGAAAACTGTCTTGGGCCCAGACACTG
CGGAGCCTGCCACAGCAGAGGCAGCTGTTGCCCCGCCGGATGCTGGCCTCCCCTTGCCAGGCCTACCAGCAGAGGGCTCACCACCACCAA
AGACCTACGTGAGCTGCCTGAAGAGCCTTCTGTCCAGCCCCACCAAGGACAGTAAGCCAAATATCTCTGCACACCACATCTCCCTGGCCT
CCTGCCTGGCACTGACCACCCCCAGTGAAGAGTTGCCGGACCGGGCAGGCATCCTGGTGGAAGATGCCACCTGTGTCACCTGCATGTCAG
ACAGCAGCCAAAGTGTCCCTTTGGTGGCTTCTCCAGGACACTGCTCAGATTCTTTCAGCACTTCAGGGCTTGAAGACTCTTGCACAGAGA
CCAGCTCGAGCCCCAGGGACAAGGCCATCACCCCGCCACTGCCAGAAAGTACTGTGCCCTTCAGCAATGGGGTGCTGAAGGGGGAGTTGT
CAGACTTGGGGGCTGAGGATGGATGGACCATGGATGCGGAAGCAGATCATTCAGGAGGAATACATGCACCACCTGCTCGCCCTGGAGCAT
CGCGCTGAGGAGCAGTTCCTGGAGCACTGGCTGAACCCTCACTGCAAACCCCACTGTGACAGGAACAGGATTCATCCTGTGTAAGGGGAT
CAGGACCAGCCTCGCAAGCATTTTAATAGACAACAAGCTGGATAATGTCGAAGCAAGACAAGGCTGCTTCTTTCACTTGTTTTTAAATTG
CAGAAATGGATGTCTTCAGACCTCGTGAACTGTGGGCATATCAAAGATTGCCTTGGAAATGGCAAATATATATACTGCTTCATTTTACTA
ACCTGCATAGATCACTAAAACCAATAGCTTAAAGCATAGACACCTCCCAAAGGTCTTCCCATCAGTTTGCAAGAGTGGGAACAACCAGAA
TCTTACCTGGGGTTGATGGAGCTGGAACTCCCAGACCAGGAGTTGGGGCAGGCTGCCTGCCCTAAGGAATTTGGGGAATCCTTGTTCAGA
GTAGTGAAGCATACCACTTGGGGTTGCTGAGTTGTTTTGTCCTCTATTTTTTTCCTCTTCTTTTCTGCCCTAATAAACATTGGTATTAAA

>3333_3333_4_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000337714_C17orf67_chr17_54872541_ENST00000575658_length(amino acids)=584AA_BP=
MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKELSTVSKLPA
EPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQP
GYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSR
FIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEAT
EQVLATTVGKVAGRVCQASQLQGQKEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDS
KPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPEST

--------------------------------------------------------------
>3333_3333_5_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000539273_C17orf67_chr17_54872541_ENST00000397861_length(transcript)=2501nt_BP=1924nt
GTGACTTACACAGGCCCCTGAGGATGAAGGTAACAGTCCTGTGAGCACTGAGGCTGGGCTGGGACCAACACCTGAGCCATGGCTCCAGCA
CTCTGATTCCTGGCCCAGCCATGCTGCTGAGGGTGCACAGCCCAGGCCTACCATCGCCCCCACCCTTGGTGGCAGAACCGAGCACTACCC
AGCAAGGTGTAATTACTTCAAGCCTCCAGGATGGCAATCCAGTTCCGTTCGCTCTTCCCCTTGGCATTGCCTGGGATGCTGGCGCTCCTC
GGCTGGTGGTGGTTTTTCTCTCGTAAAAAAGGCCATGTCAGCAGCCATGATGAGCAGCAGGTGGAGGCTGGTGCTGTGCAGCTGAGGGCT
GACCCTGCCATCAAGGAACCTCTCCCCGTGGAAGACGTCTGTCCCAAAGTAGTGTCCACACCCCCCAGTGTCACAGAGCCTCCAGAAAAG
GAACTGTCCACCGTGAGCAAGCTGCCTGCAGAGCCCCCAGCATTGCTCCAGACACACCCACCTTGCCGAAGATCAGAGTCCTCGGGCATT
CTTCCTAACACCACAGACATGAGATTGCGACCAGGAACACGCAGAGATGACAGTACAAAGCTGGAGCTAGCCCTGACAGGTGGTGAAGCC
AAATCGATTCCTCTAGAGTGCCCCCTTTCATCCCCAAAGGGTGTACTATTCTCCAGCAAATCAGCTGAGGTGTGTAAGCAAGATTCCCCC
TTCAGCAGGGTGCCAAGGAAGGTCCAGCCAGGCTACCCCGTAGTCCCCGCAGAGAAGCGTAGCTCTGGGGAGAGGGCAAGAGAGACAGGT
GGGGCCGAAGGGACTGGTGATGCCGTGTTGGGGGAAAAGGTGCTTGAAGAAGCTCTGTTGTCTCGGGAGCATGTCTTGGAATTGGAGAAC
AGCAAGGGCCCCAGCCTGGCCTCTTTAGAGGGGGAAGAAGATAAGGGGAAGAGCAGCTCATCCCAGGTGGTGGGGCCAGTGCAGGAGGAA
GAGTATGTAGCAGAGAAGTTGCCAAGTAGGTTCATCGAGTCGGCTCACACAGAGCTGGCAAAGGACGATGCGGCGCCAGCACCCCCAGTC
GCAGACGCCAAAGCCCAGGATAGAGGTGTCGAGGGAGAACTGGGCAATGAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAAT
GAGGAGGGCTTGGATAGAAATGAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGATTAAGCGGGCTGCCTTCCAG
ATAATCTCCCAAGTGATCTCAGAAGCAACCGAACAGGTGCTGGCCACCACGGTTGGCAAGGTTGCAGGTCGTGTGTGTCAGGCCAGTCAG
CTCCAAGGGCAGAAGGAAGAGAGCTGTGTCCCAGTTCACCAGAAAACTGTCTTGGGCCCAGACACTGCGGAGCCTGCCACAGCAGAGGCA
GCTGTTGCCCCGCCGGATGCTGGCCTCCCCTTGCCAGGCCTACCAGCAGAGGGCTCACCACCACCAAAGACCTACGTGAGCTGCCTGAAG
AGCCTTCTGTCCAGCCCCACCAAGGACAGTAAGCCAAATATCTCTGCACACCACATCTCCCTGGCCTCCTGCCTGGCACTGACCACCCCC
AGTGAAGAGTTGCCGGACCGGGCAGGCATCCTGGTGGAAGATGCCACCTGTGTCACCTGCATGTCAGACAGCAGCCAAAGTGTCCCTTTG
GTGGCTTCTCCAGGACACTGCTCAGATTCTTTCAGCACTTCAGGGCTTGAAGACTCTTGCACAGAGACCAGCTCGAGCCCCAGGGACAAG
GCCATCACCCCGCCACTGCCAGAAAGTACTGTGCCCTTCAGCAATGGGGTGCTGAAGGGGGAGTTGTCAGACTTGGGGGCTGAGGATGGA
TGGACCATGGATGCGGAAGCAGATCATTCAGGAGGAATACATGCACCACCTGCTCGCCCTGGAGCATCGCGCTGAGGAGCAGTTCCTGGA
GCACTGGCTGAACCCTCACTGCAAACCCCACTGTGACAGGAACAGGATTCATCCTGTGTAAGGGGATCAGGACCAGCCTCGCAAGCATTT
TAATAGACAACAAGCTGGATAATGTCGAAGCAAGACAAGGCTGCTTCTTTCACTTGTTTTTAAATTGCAGAAATGGATGTCTTCAGACCT
CGTGAACTGTGGGCATATCAAAGATTGCCTTGGAAATGGCAAATATATATACTGCTTCATTTTACTAACCTGCATAGATCACTAAAACCA
ATAGCTTAAAGCATAGACACCTCCCAAAGGTCTTCCCATCAGTTTGCAAGAGTGGGAACAACCAGAATCTTACCTGGGGTTGATGGAGCT
GGAACTCCCAGACCAGGAGTTGGGGCAGGCTGCCTGCCCTAAGGAATTTGGGGAATCCTTGTTCAGAGTAGTGAAGCATACCACTTGGGG

>3333_3333_5_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000539273_C17orf67_chr17_54872541_ENST00000397861_length(amino acids)=584AA_BP=
MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKELSTVSKLPA
EPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQP
GYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSR
FIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEAT
EQVLATTVGKVAGRVCQASQLQGQKEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDS
KPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPEST

--------------------------------------------------------------
>3333_3333_6_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000539273_C17orf67_chr17_54872541_ENST00000575658_length(transcript)=2500nt_BP=1924nt
GTGACTTACACAGGCCCCTGAGGATGAAGGTAACAGTCCTGTGAGCACTGAGGCTGGGCTGGGACCAACACCTGAGCCATGGCTCCAGCA
CTCTGATTCCTGGCCCAGCCATGCTGCTGAGGGTGCACAGCCCAGGCCTACCATCGCCCCCACCCTTGGTGGCAGAACCGAGCACTACCC
AGCAAGGTGTAATTACTTCAAGCCTCCAGGATGGCAATCCAGTTCCGTTCGCTCTTCCCCTTGGCATTGCCTGGGATGCTGGCGCTCCTC
GGCTGGTGGTGGTTTTTCTCTCGTAAAAAAGGCCATGTCAGCAGCCATGATGAGCAGCAGGTGGAGGCTGGTGCTGTGCAGCTGAGGGCT
GACCCTGCCATCAAGGAACCTCTCCCCGTGGAAGACGTCTGTCCCAAAGTAGTGTCCACACCCCCCAGTGTCACAGAGCCTCCAGAAAAG
GAACTGTCCACCGTGAGCAAGCTGCCTGCAGAGCCCCCAGCATTGCTCCAGACACACCCACCTTGCCGAAGATCAGAGTCCTCGGGCATT
CTTCCTAACACCACAGACATGAGATTGCGACCAGGAACACGCAGAGATGACAGTACAAAGCTGGAGCTAGCCCTGACAGGTGGTGAAGCC
AAATCGATTCCTCTAGAGTGCCCCCTTTCATCCCCAAAGGGTGTACTATTCTCCAGCAAATCAGCTGAGGTGTGTAAGCAAGATTCCCCC
TTCAGCAGGGTGCCAAGGAAGGTCCAGCCAGGCTACCCCGTAGTCCCCGCAGAGAAGCGTAGCTCTGGGGAGAGGGCAAGAGAGACAGGT
GGGGCCGAAGGGACTGGTGATGCCGTGTTGGGGGAAAAGGTGCTTGAAGAAGCTCTGTTGTCTCGGGAGCATGTCTTGGAATTGGAGAAC
AGCAAGGGCCCCAGCCTGGCCTCTTTAGAGGGGGAAGAAGATAAGGGGAAGAGCAGCTCATCCCAGGTGGTGGGGCCAGTGCAGGAGGAA
GAGTATGTAGCAGAGAAGTTGCCAAGTAGGTTCATCGAGTCGGCTCACACAGAGCTGGCAAAGGACGATGCGGCGCCAGCACCCCCAGTC
GCAGACGCCAAAGCCCAGGATAGAGGTGTCGAGGGAGAACTGGGCAATGAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAAT
GAGGAGGGCTTGGATAGAAATGAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGATTAAGCGGGCTGCCTTCCAG
ATAATCTCCCAAGTGATCTCAGAAGCAACCGAACAGGTGCTGGCCACCACGGTTGGCAAGGTTGCAGGTCGTGTGTGTCAGGCCAGTCAG
CTCCAAGGGCAGAAGGAAGAGAGCTGTGTCCCAGTTCACCAGAAAACTGTCTTGGGCCCAGACACTGCGGAGCCTGCCACAGCAGAGGCA
GCTGTTGCCCCGCCGGATGCTGGCCTCCCCTTGCCAGGCCTACCAGCAGAGGGCTCACCACCACCAAAGACCTACGTGAGCTGCCTGAAG
AGCCTTCTGTCCAGCCCCACCAAGGACAGTAAGCCAAATATCTCTGCACACCACATCTCCCTGGCCTCCTGCCTGGCACTGACCACCCCC
AGTGAAGAGTTGCCGGACCGGGCAGGCATCCTGGTGGAAGATGCCACCTGTGTCACCTGCATGTCAGACAGCAGCCAAAGTGTCCCTTTG
GTGGCTTCTCCAGGACACTGCTCAGATTCTTTCAGCACTTCAGGGCTTGAAGACTCTTGCACAGAGACCAGCTCGAGCCCCAGGGACAAG
GCCATCACCCCGCCACTGCCAGAAAGTACTGTGCCCTTCAGCAATGGGGTGCTGAAGGGGGAGTTGTCAGACTTGGGGGCTGAGGATGGA
TGGACCATGGATGCGGAAGCAGATCATTCAGGAGGAATACATGCACCACCTGCTCGCCCTGGAGCATCGCGCTGAGGAGCAGTTCCTGGA
GCACTGGCTGAACCCTCACTGCAAACCCCACTGTGACAGGAACAGGATTCATCCTGTGTAAGGGGATCAGGACCAGCCTCGCAAGCATTT
TAATAGACAACAAGCTGGATAATGTCGAAGCAAGACAAGGCTGCTTCTTTCACTTGTTTTTAAATTGCAGAAATGGATGTCTTCAGACCT
CGTGAACTGTGGGCATATCAAAGATTGCCTTGGAAATGGCAAATATATATACTGCTTCATTTTACTAACCTGCATAGATCACTAAAACCA
ATAGCTTAAAGCATAGACACCTCCCAAAGGTCTTCCCATCAGTTTGCAAGAGTGGGAACAACCAGAATCTTACCTGGGGTTGATGGAGCT
GGAACTCCCAGACCAGGAGTTGGGGCAGGCTGCCTGCCCTAAGGAATTTGGGGAATCCTTGTTCAGAGTAGTGAAGCATACCACTTGGGG

>3333_3333_6_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000539273_C17orf67_chr17_54872541_ENST00000575658_length(amino acids)=584AA_BP=
MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKELSTVSKLPA
EPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQP
GYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSR
FIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEAT
EQVLATTVGKVAGRVCQASQLQGQKEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDS
KPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPEST

--------------------------------------------------------------
>3333_3333_7_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000571629_C17orf67_chr17_54872541_ENST00000397861_length(transcript)=2633nt_BP=2056nt
GTCACTGTCCTCGGGGGCGGGGGGCGAGGGCGCGACGCCCGGGTCGCCTCTCTGCACCTCAACTTAACCGGAGCGTGCACACCCGCCTGC
GAGGCTGACCCGAGCGCGTCCCACCCAAGGTCGCCCAGCCCCGCGGGCGTTTACTTTTCAAAGGGAGGGATAGGAGAAGAAAGGTGCTGA
TCGTGGTAGGCGGTGCTGTGGCGACTCGGAACGGCATGGGAGCCCTGGGCGTTTCGGGATCTTCCTCTCCTGGGGGATGTCCTGGGTGGC
GGCGCCTTCCTGCCGCCGTTAACACAAACCCGGTGGACTTCGCTCCAGGTGTAATTACTTCAAGCCTCCAGGATGGCAATCCAGTTCCGT
TCGCTCTTCCCCTTGGCATTGCCTGGGATGCTGGCGCTCCTCGGCTGGTGGTGGTTTTTCTCTCGTAAAAAAGGCCATGTCAGCAGCCAT
GATGAGCAGCAGGTGGAGGCTGGTGCTGTGCAGCTGAGGGCTGACCCTGCCATCAAGGAACCTCTCCCCGTGGAAGACGTCTGTCCCAAA
GTAGTGTCCACACCCCCCAGTGTCACAGAGCCTCCAGAAAAGGAACTGTCCACCGTGAGCAAGCTGCCTGCAGAGCCCCCAGCATTGCTC
CAGACACACCCACCTTGCCGAAGATCAGAGTCCTCGGGCATTCTTCCTAACACCACAGACATGAGATTGCGACCAGGAACACGCAGAGAT
GACAGTACAAAGCTGGAGCTAGCCCTGACAGGTGGTGAAGCCAAATCGATTCCTCTAGAGTGCCCCCTTTCATCCCCAAAGGGTGTACTA
TTCTCCAGCAAATCAGCTGAGGTGTGTAAGCAAGATTCCCCCTTCAGCAGGGTGCCAAGGAAGGTCCAGCCAGGCTACCCCGTAGTCCCC
GCAGAGAAGCGTAGCTCTGGGGAGAGGGCAAGAGAGACAGGTGGGGCCGAAGGGACTGGTGATGCCGTGTTGGGGGAAAAGGTGCTTGAA
GAAGCTCTGTTGTCTCGGGAGCATGTCTTGGAATTGGAGAACAGCAAGGGCCCCAGCCTGGCCTCTTTAGAGGGGGAAGAAGATAAGGGG
AAGAGCAGCTCATCCCAGGTGGTGGGGCCAGTGCAGGAGGAAGAGTATGTAGCAGAGAAGTTGCCAAGTAGGTTCATCGAGTCGGCTCAC
ACAGAGCTGGCAAAGGACGATGCGGCGCCAGCACCCCCAGTCGCAGACGCCAAAGCCCAGGATAGAGGTGTCGAGGGAGAACTGGGCAAT
GAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGAGCTTGGATAGAAATGAGGAG
GGCTTGGATAGAAATGAGGAGATTAAGCGGGCTGCCTTCCAGATAATCTCCCAAGTGATCTCAGAAGCAACCGAACAGGTGCTGGCCACC
ACGGTTGGCAAGGTTGCAGGTCGTGTGTGTCAGGCCAGTCAGCTCCAAGGGCAGAAGGAAGAGAGCTGTGTCCCAGTTCACCAGAAAACT
GTCTTGGGCCCAGACACTGCGGAGCCTGCCACAGCAGAGGCAGCTGTTGCCCCGCCGGATGCTGGCCTCCCCTTGCCAGGCCTACCAGCA
GAGGGCTCACCACCACCAAAGACCTACGTGAGCTGCCTGAAGAGCCTTCTGTCCAGCCCCACCAAGGACAGTAAGCCAAATATCTCTGCA
CACCACATCTCCCTGGCCTCCTGCCTGGCACTGACCACCCCCAGTGAAGAGTTGCCGGACCGGGCAGGCATCCTGGTGGAAGATGCCACC
TGTGTCACCTGCATGTCAGACAGCAGCCAAAGTGTCCCTTTGGTGGCTTCTCCAGGACACTGCTCAGATTCTTTCAGCACTTCAGGGCTT
GAAGACTCTTGCACAGAGACCAGCTCGAGCCCCAGGGACAAGGCCATCACCCCGCCACTGCCAGAAAGTACTGTGCCCTTCAGCAATGGG
GTGCTGAAGGGGGAGTTGTCAGACTTGGGGGCTGAGGATGGATGGACCATGGATGCGGAAGCAGATCATTCAGGAGGAATACATGCACCA
CCTGCTCGCCCTGGAGCATCGCGCTGAGGAGCAGTTCCTGGAGCACTGGCTGAACCCTCACTGCAAACCCCACTGTGACAGGAACAGGAT
TCATCCTGTGTAAGGGGATCAGGACCAGCCTCGCAAGCATTTTAATAGACAACAAGCTGGATAATGTCGAAGCAAGACAAGGCTGCTTCT
TTCACTTGTTTTTAAATTGCAGAAATGGATGTCTTCAGACCTCGTGAACTGTGGGCATATCAAAGATTGCCTTGGAAATGGCAAATATAT
ATACTGCTTCATTTTACTAACCTGCATAGATCACTAAAACCAATAGCTTAAAGCATAGACACCTCCCAAAGGTCTTCCCATCAGTTTGCA
AGAGTGGGAACAACCAGAATCTTACCTGGGGTTGATGGAGCTGGAACTCCCAGACCAGGAGTTGGGGCAGGCTGCCTGCCCTAAGGAATT
TGGGGAATCCTTGTTCAGAGTAGTGAAGCATACCACTTGGGGTTGCTGAGTTGTTTTGTCCTCTATTTTTTTCCTCTTCTTTTCTGCCCT

>3333_3333_7_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000571629_C17orf67_chr17_54872541_ENST00000397861_length(amino acids)=584AA_BP=
MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKELSTVSKLPA
EPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQP
GYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSR
FIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEAT
EQVLATTVGKVAGRVCQASQLQGQKEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDS
KPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPEST

--------------------------------------------------------------
>3333_3333_8_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000571629_C17orf67_chr17_54872541_ENST00000575658_length(transcript)=2632nt_BP=2056nt
GTCACTGTCCTCGGGGGCGGGGGGCGAGGGCGCGACGCCCGGGTCGCCTCTCTGCACCTCAACTTAACCGGAGCGTGCACACCCGCCTGC
GAGGCTGACCCGAGCGCGTCCCACCCAAGGTCGCCCAGCCCCGCGGGCGTTTACTTTTCAAAGGGAGGGATAGGAGAAGAAAGGTGCTGA
TCGTGGTAGGCGGTGCTGTGGCGACTCGGAACGGCATGGGAGCCCTGGGCGTTTCGGGATCTTCCTCTCCTGGGGGATGTCCTGGGTGGC
GGCGCCTTCCTGCCGCCGTTAACACAAACCCGGTGGACTTCGCTCCAGGTGTAATTACTTCAAGCCTCCAGGATGGCAATCCAGTTCCGT
TCGCTCTTCCCCTTGGCATTGCCTGGGATGCTGGCGCTCCTCGGCTGGTGGTGGTTTTTCTCTCGTAAAAAAGGCCATGTCAGCAGCCAT
GATGAGCAGCAGGTGGAGGCTGGTGCTGTGCAGCTGAGGGCTGACCCTGCCATCAAGGAACCTCTCCCCGTGGAAGACGTCTGTCCCAAA
GTAGTGTCCACACCCCCCAGTGTCACAGAGCCTCCAGAAAAGGAACTGTCCACCGTGAGCAAGCTGCCTGCAGAGCCCCCAGCATTGCTC
CAGACACACCCACCTTGCCGAAGATCAGAGTCCTCGGGCATTCTTCCTAACACCACAGACATGAGATTGCGACCAGGAACACGCAGAGAT
GACAGTACAAAGCTGGAGCTAGCCCTGACAGGTGGTGAAGCCAAATCGATTCCTCTAGAGTGCCCCCTTTCATCCCCAAAGGGTGTACTA
TTCTCCAGCAAATCAGCTGAGGTGTGTAAGCAAGATTCCCCCTTCAGCAGGGTGCCAAGGAAGGTCCAGCCAGGCTACCCCGTAGTCCCC
GCAGAGAAGCGTAGCTCTGGGGAGAGGGCAAGAGAGACAGGTGGGGCCGAAGGGACTGGTGATGCCGTGTTGGGGGAAAAGGTGCTTGAA
GAAGCTCTGTTGTCTCGGGAGCATGTCTTGGAATTGGAGAACAGCAAGGGCCCCAGCCTGGCCTCTTTAGAGGGGGAAGAAGATAAGGGG
AAGAGCAGCTCATCCCAGGTGGTGGGGCCAGTGCAGGAGGAAGAGTATGTAGCAGAGAAGTTGCCAAGTAGGTTCATCGAGTCGGCTCAC
ACAGAGCTGGCAAAGGACGATGCGGCGCCAGCACCCCCAGTCGCAGACGCCAAAGCCCAGGATAGAGGTGTCGAGGGAGAACTGGGCAAT
GAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGAGCTTGGATAGAAATGAGGAG
GGCTTGGATAGAAATGAGGAGATTAAGCGGGCTGCCTTCCAGATAATCTCCCAAGTGATCTCAGAAGCAACCGAACAGGTGCTGGCCACC
ACGGTTGGCAAGGTTGCAGGTCGTGTGTGTCAGGCCAGTCAGCTCCAAGGGCAGAAGGAAGAGAGCTGTGTCCCAGTTCACCAGAAAACT
GTCTTGGGCCCAGACACTGCGGAGCCTGCCACAGCAGAGGCAGCTGTTGCCCCGCCGGATGCTGGCCTCCCCTTGCCAGGCCTACCAGCA
GAGGGCTCACCACCACCAAAGACCTACGTGAGCTGCCTGAAGAGCCTTCTGTCCAGCCCCACCAAGGACAGTAAGCCAAATATCTCTGCA
CACCACATCTCCCTGGCCTCCTGCCTGGCACTGACCACCCCCAGTGAAGAGTTGCCGGACCGGGCAGGCATCCTGGTGGAAGATGCCACC
TGTGTCACCTGCATGTCAGACAGCAGCCAAAGTGTCCCTTTGGTGGCTTCTCCAGGACACTGCTCAGATTCTTTCAGCACTTCAGGGCTT
GAAGACTCTTGCACAGAGACCAGCTCGAGCCCCAGGGACAAGGCCATCACCCCGCCACTGCCAGAAAGTACTGTGCCCTTCAGCAATGGG
GTGCTGAAGGGGGAGTTGTCAGACTTGGGGGCTGAGGATGGATGGACCATGGATGCGGAAGCAGATCATTCAGGAGGAATACATGCACCA
CCTGCTCGCCCTGGAGCATCGCGCTGAGGAGCAGTTCCTGGAGCACTGGCTGAACCCTCACTGCAAACCCCACTGTGACAGGAACAGGAT
TCATCCTGTGTAAGGGGATCAGGACCAGCCTCGCAAGCATTTTAATAGACAACAAGCTGGATAATGTCGAAGCAAGACAAGGCTGCTTCT
TTCACTTGTTTTTAAATTGCAGAAATGGATGTCTTCAGACCTCGTGAACTGTGGGCATATCAAAGATTGCCTTGGAAATGGCAAATATAT
ATACTGCTTCATTTTACTAACCTGCATAGATCACTAAAACCAATAGCTTAAAGCATAGACACCTCCCAAAGGTCTTCCCATCAGTTTGCA
AGAGTGGGAACAACCAGAATCTTACCTGGGGTTGATGGAGCTGGAACTCCCAGACCAGGAGTTGGGGCAGGCTGCCTGCCCTAAGGAATT
TGGGGAATCCTTGTTCAGAGTAGTGAAGCATACCACTTGGGGTTGCTGAGTTGTTTTGTCCTCTATTTTTTTCCTCTTCTTTTCTGCCCT

>3333_3333_8_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000571629_C17orf67_chr17_54872541_ENST00000575658_length(amino acids)=584AA_BP=
MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKELSTVSKLPA
EPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQP
GYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSR
FIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEAT
EQVLATTVGKVAGRVCQASQLQGQKEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDS
KPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPEST

--------------------------------------------------------------
>3333_3333_9_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000572557_C17orf67_chr17_54872541_ENST00000397861_length(transcript)=2431nt_BP=1854nt
GAACTCCATGTACCCAGGAAGGCATTCCTGGCACCTGTGTTGTGACCATCTTTAGAAACCTGGCGGAATTCACTTGTAAAGCAAGATGGT
TGTCAAGGCCAGAGGTGAGGGGCAAGGTGTAATTACTTCAAGCCTCCAGGATGGCAATCCAGTTCCGTTCGCTCTTCCCCTTGGCATTGC
CTGGGATGCTGGCGCTCCTCGGCTGGTGGTGGTTTTTCTCTCGTAAAAAAGGCCATGTCAGCAGCCATGATGAGCAGCAGGTGGAGGCTG
GTGCTGTGCAGCTGAGGGCTGACCCTGCCATCAAGGAACCTCTCCCCGTGGAAGACGTCTGTCCCAAAGTAGTGTCCACACCCCCCAGTG
TCACAGAGCCTCCAGAAAAGGAACTGTCCACCGTGAGCAAGCTGCCTGCAGAGCCCCCAGCATTGCTCCAGACACACCCACCTTGCCGAA
GATCAGAGTCCTCGGGCATTCTTCCTAACACCACAGACATGAGATTGCGACCAGGAACACGCAGAGATGACAGTACAAAGCTGGAGCTAG
CCCTGACAGGTGGTGAAGCCAAATCGATTCCTCTAGAGTGCCCCCTTTCATCCCCAAAGGGTGTACTATTCTCCAGCAAATCAGCTGAGG
TGTGTAAGCAAGATTCCCCCTTCAGCAGGGTGCCAAGGAAGGTCCAGCCAGGCTACCCCGTAGTCCCCGCAGAGAAGCGTAGCTCTGGGG
AGAGGGCAAGAGAGACAGGTGGGGCCGAAGGGACTGGTGATGCCGTGTTGGGGGAAAAGGTGCTTGAAGAAGCTCTGTTGTCTCGGGAGC
ATGTCTTGGAATTGGAGAACAGCAAGGGCCCCAGCCTGGCCTCTTTAGAGGGGGAAGAAGATAAGGGGAAGAGCAGCTCATCCCAGGTGG
TGGGGCCAGTGCAGGAGGAAGAGTATGTAGCAGAGAAGTTGCCAAGTAGGTTCATCGAGTCGGCTCACACAGAGCTGGCAAAGGACGATG
CGGCGCCAGCACCCCCAGTCGCAGACGCCAAAGCCCAGGATAGAGGTGTCGAGGGAGAACTGGGCAATGAGGAGAGCTTGGATAGAAATG
AGGAGGGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGA
TTAAGCGGGCTGCCTTCCAGATAATCTCCCAAGTGATCTCAGAAGCAACCGAACAGGTGCTGGCCACCACGGTTGGCAAGGTTGCAGGTC
GTGTGTGTCAGGCCAGTCAGCTCCAAGGGCAGAAGGAAGAGAGCTGTGTCCCAGTTCACCAGAAAACTGTCTTGGGCCCAGACACTGCGG
AGCCTGCCACAGCAGAGGCAGCTGTTGCCCCGCCGGATGCTGGCCTCCCCTTGCCAGGCCTACCAGCAGAGGGCTCACCACCACCAAAGA
CCTACGTGAGCTGCCTGAAGAGCCTTCTGTCCAGCCCCACCAAGGACAGTAAGCCAAATATCTCTGCACACCACATCTCCCTGGCCTCCT
GCCTGGCACTGACCACCCCCAGTGAAGAGTTGCCGGACCGGGCAGGCATCCTGGTGGAAGATGCCACCTGTGTCACCTGCATGTCAGACA
GCAGCCAAAGTGTCCCTTTGGTGGCTTCTCCAGGACACTGCTCAGATTCTTTCAGCACTTCAGGGCTTGAAGACTCTTGCACAGAGACCA
GCTCGAGCCCCAGGGACAAGGCCATCACCCCGCCACTGCCAGAAAGTACTGTGCCCTTCAGCAATGGGGTGCTGAAGGGGGAGTTGTCAG
ACTTGGGGGCTGAGGATGGATGGACCATGGATGCGGAAGCAGATCATTCAGGAGGAATACATGCACCACCTGCTCGCCCTGGAGCATCGC
GCTGAGGAGCAGTTCCTGGAGCACTGGCTGAACCCTCACTGCAAACCCCACTGTGACAGGAACAGGATTCATCCTGTGTAAGGGGATCAG
GACCAGCCTCGCAAGCATTTTAATAGACAACAAGCTGGATAATGTCGAAGCAAGACAAGGCTGCTTCTTTCACTTGTTTTTAAATTGCAG
AAATGGATGTCTTCAGACCTCGTGAACTGTGGGCATATCAAAGATTGCCTTGGAAATGGCAAATATATATACTGCTTCATTTTACTAACC
TGCATAGATCACTAAAACCAATAGCTTAAAGCATAGACACCTCCCAAAGGTCTTCCCATCAGTTTGCAAGAGTGGGAACAACCAGAATCT
TACCTGGGGTTGATGGAGCTGGAACTCCCAGACCAGGAGTTGGGGCAGGCTGCCTGCCCTAAGGAATTTGGGGAATCCTTGTTCAGAGTA
GTGAAGCATACCACTTGGGGTTGCTGAGTTGTTTTGTCCTCTATTTTTTTCCTCTTCTTTTCTGCCCTAATAAACATTGGTATTAAATTT

>3333_3333_9_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000572557_C17orf67_chr17_54872541_ENST00000397861_length(amino acids)=584AA_BP=
MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKELSTVSKLPA
EPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQP
GYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSR
FIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEAT
EQVLATTVGKVAGRVCQASQLQGQKEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDS
KPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPEST

--------------------------------------------------------------
>3333_3333_10_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000572557_C17orf67_chr17_54872541_ENST00000575658_length(transcript)=2430nt_BP=1854nt
GAACTCCATGTACCCAGGAAGGCATTCCTGGCACCTGTGTTGTGACCATCTTTAGAAACCTGGCGGAATTCACTTGTAAAGCAAGATGGT
TGTCAAGGCCAGAGGTGAGGGGCAAGGTGTAATTACTTCAAGCCTCCAGGATGGCAATCCAGTTCCGTTCGCTCTTCCCCTTGGCATTGC
CTGGGATGCTGGCGCTCCTCGGCTGGTGGTGGTTTTTCTCTCGTAAAAAAGGCCATGTCAGCAGCCATGATGAGCAGCAGGTGGAGGCTG
GTGCTGTGCAGCTGAGGGCTGACCCTGCCATCAAGGAACCTCTCCCCGTGGAAGACGTCTGTCCCAAAGTAGTGTCCACACCCCCCAGTG
TCACAGAGCCTCCAGAAAAGGAACTGTCCACCGTGAGCAAGCTGCCTGCAGAGCCCCCAGCATTGCTCCAGACACACCCACCTTGCCGAA
GATCAGAGTCCTCGGGCATTCTTCCTAACACCACAGACATGAGATTGCGACCAGGAACACGCAGAGATGACAGTACAAAGCTGGAGCTAG
CCCTGACAGGTGGTGAAGCCAAATCGATTCCTCTAGAGTGCCCCCTTTCATCCCCAAAGGGTGTACTATTCTCCAGCAAATCAGCTGAGG
TGTGTAAGCAAGATTCCCCCTTCAGCAGGGTGCCAAGGAAGGTCCAGCCAGGCTACCCCGTAGTCCCCGCAGAGAAGCGTAGCTCTGGGG
AGAGGGCAAGAGAGACAGGTGGGGCCGAAGGGACTGGTGATGCCGTGTTGGGGGAAAAGGTGCTTGAAGAAGCTCTGTTGTCTCGGGAGC
ATGTCTTGGAATTGGAGAACAGCAAGGGCCCCAGCCTGGCCTCTTTAGAGGGGGAAGAAGATAAGGGGAAGAGCAGCTCATCCCAGGTGG
TGGGGCCAGTGCAGGAGGAAGAGTATGTAGCAGAGAAGTTGCCAAGTAGGTTCATCGAGTCGGCTCACACAGAGCTGGCAAAGGACGATG
CGGCGCCAGCACCCCCAGTCGCAGACGCCAAAGCCCAGGATAGAGGTGTCGAGGGAGAACTGGGCAATGAGGAGAGCTTGGATAGAAATG
AGGAGGGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGAGCTTGGATAGAAATGAGGAGGGCTTGGATAGAAATGAGGAGA
TTAAGCGGGCTGCCTTCCAGATAATCTCCCAAGTGATCTCAGAAGCAACCGAACAGGTGCTGGCCACCACGGTTGGCAAGGTTGCAGGTC
GTGTGTGTCAGGCCAGTCAGCTCCAAGGGCAGAAGGAAGAGAGCTGTGTCCCAGTTCACCAGAAAACTGTCTTGGGCCCAGACACTGCGG
AGCCTGCCACAGCAGAGGCAGCTGTTGCCCCGCCGGATGCTGGCCTCCCCTTGCCAGGCCTACCAGCAGAGGGCTCACCACCACCAAAGA
CCTACGTGAGCTGCCTGAAGAGCCTTCTGTCCAGCCCCACCAAGGACAGTAAGCCAAATATCTCTGCACACCACATCTCCCTGGCCTCCT
GCCTGGCACTGACCACCCCCAGTGAAGAGTTGCCGGACCGGGCAGGCATCCTGGTGGAAGATGCCACCTGTGTCACCTGCATGTCAGACA
GCAGCCAAAGTGTCCCTTTGGTGGCTTCTCCAGGACACTGCTCAGATTCTTTCAGCACTTCAGGGCTTGAAGACTCTTGCACAGAGACCA
GCTCGAGCCCCAGGGACAAGGCCATCACCCCGCCACTGCCAGAAAGTACTGTGCCCTTCAGCAATGGGGTGCTGAAGGGGGAGTTGTCAG
ACTTGGGGGCTGAGGATGGATGGACCATGGATGCGGAAGCAGATCATTCAGGAGGAATACATGCACCACCTGCTCGCCCTGGAGCATCGC
GCTGAGGAGCAGTTCCTGGAGCACTGGCTGAACCCTCACTGCAAACCCCACTGTGACAGGAACAGGATTCATCCTGTGTAAGGGGATCAG
GACCAGCCTCGCAAGCATTTTAATAGACAACAAGCTGGATAATGTCGAAGCAAGACAAGGCTGCTTCTTTCACTTGTTTTTAAATTGCAG
AAATGGATGTCTTCAGACCTCGTGAACTGTGGGCATATCAAAGATTGCCTTGGAAATGGCAAATATATATACTGCTTCATTTTACTAACC
TGCATAGATCACTAAAACCAATAGCTTAAAGCATAGACACCTCCCAAAGGTCTTCCCATCAGTTTGCAAGAGTGGGAACAACCAGAATCT
TACCTGGGGTTGATGGAGCTGGAACTCCCAGACCAGGAGTTGGGGCAGGCTGCCTGCCCTAAGGAATTTGGGGAATCCTTGTTCAGAGTA
GTGAAGCATACCACTTGGGGTTGCTGAGTTGTTTTGTCCTCTATTTTTTTCCTCTTCTTTTCTGCCCTAATAAACATTGGTATTAAATTT

>3333_3333_10_AKAP1-C17orf67_AKAP1_chr17_55184539_ENST00000572557_C17orf67_chr17_54872541_ENST00000575658_length(amino acids)=584AA_BP=
MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKELSTVSKLPA
EPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQP
GYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSR
FIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEAT
EQVLATTVGKVAGRVCQASQLQGQKEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDS
KPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPEST

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AKAP1-C17orf67


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AKAP1-C17orf67


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AKAP1-C17orf67


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource