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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GLT8D1-PLXNB1 (FusionGDB2 ID:33366)

Fusion Gene Summary for GLT8D1-PLXNB1

check button Fusion gene summary
Fusion gene informationFusion gene name: GLT8D1-PLXNB1
Fusion gene ID: 33366
HgeneTgene
Gene symbol

GLT8D1

PLXNB1

Gene ID

55830

5364

Gene nameglycosyltransferase 8 domain containing 1plexin B1
SynonymsAD-017|MSTP139PLEXIN-B1|PLXN5|SEP
Cytomap

3p21.1

3p21.31

Type of geneprotein-codingprotein-coding
Descriptionglycosyltransferase 8 domain-containing protein 1glycosyltransferase AD-017plexin-B1plexin 5semaphorin receptor SEP
Modification date2020031320200313
UniProtAcc

Q68CQ7

.
Ensembl transtripts involved in fusion geneENST00000266014, ENST00000394783, 
ENST00000407584, ENST00000478968, 
ENST00000491606, ENST00000463827, 
ENST00000465117, ENST00000296440, 
ENST00000358459, ENST00000358536, 
ENST00000448774, ENST00000456774, 
Fusion gene scores* DoF score1 X 1 X 1=19 X 8 X 5=360
# samples 18
** MAII scorelog2(1/1*10)=3.32192809488736log2(8/360*10)=-2.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GLT8D1 [Title/Abstract] AND PLXNB1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGLT8D1(52729206)-PLXNB1(48445997), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePLXNB1

GO:0007162

negative regulation of cell adhesion

15218527

TgenePLXNB1

GO:0008360

regulation of cell shape

19843518

TgenePLXNB1

GO:0051493

regulation of cytoskeleton organization

19843518

TgenePLXNB1

GO:0071526

semaphorin-plexin signaling pathway

15218527|19843518


check buttonFusion gene breakpoints across GLT8D1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PLXNB1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4MESOTCGA-UD-AABY-01AGLT8D1chr3

52729206

-PLXNB1chr3

48445997

-


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Fusion Gene ORF analysis for GLT8D1-PLXNB1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000266014ENST00000465117GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
5CDS-intronENST00000394783ENST00000465117GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
5CDS-intronENST00000407584ENST00000465117GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
5CDS-intronENST00000478968ENST00000465117GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
5CDS-intronENST00000491606ENST00000465117GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
5UTR-3CDSENST00000463827ENST00000296440GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
5UTR-3CDSENST00000463827ENST00000358459GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
5UTR-3CDSENST00000463827ENST00000358536GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
5UTR-3CDSENST00000463827ENST00000448774GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
5UTR-3CDSENST00000463827ENST00000456774GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
5UTR-intronENST00000463827ENST00000465117GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000266014ENST00000448774GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000266014ENST00000456774GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000394783ENST00000296440GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000394783ENST00000358459GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000394783ENST00000358536GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000394783ENST00000448774GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000394783ENST00000456774GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000407584ENST00000296440GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000407584ENST00000358459GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000407584ENST00000358536GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000478968ENST00000448774GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000478968ENST00000456774GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000491606ENST00000448774GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
Frame-shiftENST00000491606ENST00000456774GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
In-frameENST00000266014ENST00000296440GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
In-frameENST00000266014ENST00000358459GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
In-frameENST00000266014ENST00000358536GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
In-frameENST00000407584ENST00000448774GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
In-frameENST00000407584ENST00000456774GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
In-frameENST00000478968ENST00000296440GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
In-frameENST00000478968ENST00000358459GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
In-frameENST00000478968ENST00000358536GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
In-frameENST00000491606ENST00000296440GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
In-frameENST00000491606ENST00000358459GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-
In-frameENST00000491606ENST00000358536GLT8D1chr3

52729206

-PLXNB1chr3

48445997

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000478968GLT8D1chr352729206-ENST00000296440PLXNB1chr348445997-201612793541481375
ENST00000478968GLT8D1chr352729206-ENST00000358459PLXNB1chr348445997-201512793541481375
ENST00000478968GLT8D1chr352729206-ENST00000358536PLXNB1chr348445997-201412793541481375
ENST00000407584GLT8D1chr352729206-ENST00000448774PLXNB1chr348445997-192217768511921357
ENST00000407584GLT8D1chr352729206-ENST00000456774PLXNB1chr348445997-188117768511879343
ENST00000266014GLT8D1chr352729206-ENST00000296440PLXNB1chr348445997-228415476221749375
ENST00000266014GLT8D1chr352729206-ENST00000358459PLXNB1chr348445997-228315476221749375
ENST00000266014GLT8D1chr352729206-ENST00000358536PLXNB1chr348445997-228215476221749375
ENST00000491606GLT8D1chr352729206-ENST00000296440PLXNB1chr348445997-178110441191246375
ENST00000491606GLT8D1chr352729206-ENST00000358459PLXNB1chr348445997-178010441191246375
ENST00000491606GLT8D1chr352729206-ENST00000358536PLXNB1chr348445997-177910441191246375

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000478968ENST00000296440GLT8D1chr352729206-PLXNB1chr348445997-0.0011422920.99885774
ENST00000478968ENST00000358459GLT8D1chr352729206-PLXNB1chr348445997-0.0011449310.9988551
ENST00000478968ENST00000358536GLT8D1chr352729206-PLXNB1chr348445997-0.0011488150.9988512
ENST00000407584ENST00000448774GLT8D1chr352729206-PLXNB1chr348445997-0.556505860.44349414
ENST00000407584ENST00000456774GLT8D1chr352729206-PLXNB1chr348445997-0.55381790.4461821
ENST00000266014ENST00000296440GLT8D1chr352729206-PLXNB1chr348445997-0.0009515390.9990484
ENST00000266014ENST00000358459GLT8D1chr352729206-PLXNB1chr348445997-0.0009465360.9990534
ENST00000266014ENST00000358536GLT8D1chr352729206-PLXNB1chr348445997-0.0009434740.9990565
ENST00000491606ENST00000296440GLT8D1chr352729206-PLXNB1chr348445997-0.0007596050.9992404
ENST00000491606ENST00000358459GLT8D1chr352729206-PLXNB1chr348445997-0.0007626410.9992374
ENST00000491606ENST00000358536GLT8D1chr352729206-PLXNB1chr348445997-0.0007663340.9992337

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Fusion Genomic Features for GLT8D1-PLXNB1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GLT8D1-PLXNB1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:52729206/chr3:48445997)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GLT8D1

Q68CQ7

.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000266014-9101_7308372.0Topological domainCytoplasmic
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000394783-9101_7308372.0Topological domainCytoplasmic
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000407584-10111_7308372.0Topological domainCytoplasmic
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000478968-10111_7308372.0Topological domainCytoplasmic
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000491606-9101_7308372.0Topological domainCytoplasmic
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000266014-9108_28308372.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000394783-9108_28308372.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000407584-10118_28308372.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000478968-10118_28308372.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000491606-9108_28308372.0TransmembraneHelical%3B Signal-anchor for type II membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000266014-91029_371308372.0Topological domainLumenal
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000394783-91029_371308372.0Topological domainLumenal
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000407584-101129_371308372.0Topological domainLumenal
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000478968-101129_371308372.0Topological domainLumenal
HgeneGLT8D1chr3:52729206chr3:48445997ENST00000491606-91029_371308372.0Topological domainLumenal
TgenePLXNB1chr3:52729206chr3:48445997ENST0000029644036381507_153921012136.0Coiled coilOntology_term=ECO:0000255
TgenePLXNB1chr3:52729206chr3:48445997ENST0000035845937391507_153919181953.0Coiled coilOntology_term=ECO:0000255
TgenePLXNB1chr3:52729206chr3:48445997ENST0000035853636381507_153921012136.0Coiled coilOntology_term=ECO:0000255
TgenePLXNB1chr3:52729206chr3:48445997ENST0000045677435371507_153919181953.0Coiled coilOntology_term=ECO:0000255
TgenePLXNB1chr3:52729206chr3:48445997ENST000002964403638678_82921012136.0Compositional biasNote=Pro-rich
TgenePLXNB1chr3:52729206chr3:48445997ENST000003584593739678_82919181953.0Compositional biasNote=Pro-rich
TgenePLXNB1chr3:52729206chr3:48445997ENST000003585363638678_82921012136.0Compositional biasNote=Pro-rich
TgenePLXNB1chr3:52729206chr3:48445997ENST000004567743537678_82919181953.0Compositional biasNote=Pro-rich
TgenePLXNB1chr3:52729206chr3:48445997ENST0000029644036381070_116021012136.0DomainNote=IPT/TIG 1
TgenePLXNB1chr3:52729206chr3:48445997ENST0000029644036381162_124921012136.0DomainNote=IPT/TIG 2
TgenePLXNB1chr3:52729206chr3:48445997ENST0000029644036381252_137521012136.0DomainNote=IPT/TIG 3
TgenePLXNB1chr3:52729206chr3:48445997ENST00000296440363820_47921012136.0DomainSema
TgenePLXNB1chr3:52729206chr3:48445997ENST0000035845937391070_116019181953.0DomainNote=IPT/TIG 1
TgenePLXNB1chr3:52729206chr3:48445997ENST0000035845937391162_124919181953.0DomainNote=IPT/TIG 2
TgenePLXNB1chr3:52729206chr3:48445997ENST0000035845937391252_137519181953.0DomainNote=IPT/TIG 3
TgenePLXNB1chr3:52729206chr3:48445997ENST00000358459373920_47919181953.0DomainSema
TgenePLXNB1chr3:52729206chr3:48445997ENST0000035853636381070_116021012136.0DomainNote=IPT/TIG 1
TgenePLXNB1chr3:52729206chr3:48445997ENST0000035853636381162_124921012136.0DomainNote=IPT/TIG 2
TgenePLXNB1chr3:52729206chr3:48445997ENST0000035853636381252_137521012136.0DomainNote=IPT/TIG 3
TgenePLXNB1chr3:52729206chr3:48445997ENST00000358536363820_47921012136.0DomainSema
TgenePLXNB1chr3:52729206chr3:48445997ENST0000045677435371070_116019181953.0DomainNote=IPT/TIG 1
TgenePLXNB1chr3:52729206chr3:48445997ENST0000045677435371162_124919181953.0DomainNote=IPT/TIG 2
TgenePLXNB1chr3:52729206chr3:48445997ENST0000045677435371252_137519181953.0DomainNote=IPT/TIG 3
TgenePLXNB1chr3:52729206chr3:48445997ENST00000456774353720_47919181953.0DomainSema
TgenePLXNB1chr3:52729206chr3:48445997ENST0000029644036381512_213521012136.0Topological domainCytoplasmic
TgenePLXNB1chr3:52729206chr3:48445997ENST00000296440363820_149021012136.0Topological domainExtracellular
TgenePLXNB1chr3:52729206chr3:48445997ENST0000035845937391512_213519181953.0Topological domainCytoplasmic
TgenePLXNB1chr3:52729206chr3:48445997ENST00000358459373920_149019181953.0Topological domainExtracellular
TgenePLXNB1chr3:52729206chr3:48445997ENST0000035853636381512_213521012136.0Topological domainCytoplasmic
TgenePLXNB1chr3:52729206chr3:48445997ENST00000358536363820_149021012136.0Topological domainExtracellular
TgenePLXNB1chr3:52729206chr3:48445997ENST0000045677435371512_213519181953.0Topological domainCytoplasmic
TgenePLXNB1chr3:52729206chr3:48445997ENST00000456774353720_149019181953.0Topological domainExtracellular
TgenePLXNB1chr3:52729206chr3:48445997ENST0000029644036381491_151121012136.0TransmembraneHelical
TgenePLXNB1chr3:52729206chr3:48445997ENST0000035845937391491_151119181953.0TransmembraneHelical
TgenePLXNB1chr3:52729206chr3:48445997ENST0000035853636381491_151121012136.0TransmembraneHelical
TgenePLXNB1chr3:52729206chr3:48445997ENST0000045677435371491_151119181953.0TransmembraneHelical


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Fusion Gene Sequence for GLT8D1-PLXNB1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>33366_33366_1_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000266014_PLXNB1_chr3_48445997_ENST00000296440_length(transcript)=2284nt_BP=1547nt
GCGCTTTTGCCGCGCCGTGCTGCCCGCGAGGGCAGCTGAGGTGGTGGTGGCGGCCGCCTTGTCGAGGCATCGCGCGCCCGTGAAGTGTTC
GCCGTCAGTGCTGTTGGGTGCCTGGAGCCGCGTCCCCCGTCCCGAAAACTGTCCTTGACAGTACTTGCGCGGCCCAACGGCCGCCGGCGC
CCCCGCGTCTCCATGGCGACGGCCTTTTTCCCTGCGAGGACCCCGGCGGCAGGGCTGCCCCGCGGCGCCTGCTTGGCGCGACGCTCTAGC
GGTTACCGCTGCGGGCTGGCTGGGCGTAGTGGGGCTGCGCGGCTGCCACGGAGCTAGAGGGCAAGTGTGCTCGGCCCAGCGTGCAGGGAA
CGCGGGCGGCCAGACAACGGGCTGGGCTCCGGGGCCTGCGGCGCGGGCGCTGAGCTGGCAGGGCGGGTCGGGGCGCGGGCTGCATCCGCA
TCTCCTCCATCGCCTGCAGTAAGGGCGGCCGCGGCGAGCCTTTGAGGGGAACGACTTGTCGGAGCCCTAACCAGGGGTATCTCTGAGCCT
GGTGGGATCCCCGGAGCGTCACATCACTTTCCGATCACTTCAAAGTGGTTAAAAACTAATATTTATATGACAGAAGAAAAAGATGTCATT
CCGTAAAGTAAACATCATCATCTTGGTCCTGGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAACTTCCTCAGCTTGAGCAGTTTGTT
AAGGAATGAGGTTACAGATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACA
AGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGCTC
CAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGGTCCTGGCTCAACAGTGATTCCCTGAAAAGCATCAGATA
CAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGACCAGGGGGAATCCATGAAACCTTTAACCTTTGC
AAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTGATATTCTTGCCCT
TTACAATACAGCACTGAAGCCAGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGG
AAACCAGTACAATTACATTGGCTATCTTGACTATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCC
TGGAGTTTTTGTTGCAAACCTGACGGAATGGAAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAAGAGGG
ACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTCCTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTG
GAATGTCCGCCACCTTGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGCAG
CTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTGCTGTTGCTTCAGCCTGGCCTGGGCAGCCCTGGAAGCT
CGGAGGAGAGGCCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAGTGGAAGGTGACTCCCAGTCTCCTGGTGGCTCTGGCCT
CGGCCCTGCTGGATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAGTACCCAGCCTGCTCCCCGAGTCCAGCGACCCTGTGAC
ACCGGTCTGCAGGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAGACTCCAGGCCCCTGGGGAGACTGTACTGTTCCTGAAC
ACTGGCCTTGGCCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTTCCTGTCTGCCTCCTCCACCATCCCTGACCTCAGTTGA
GCTGCCTCTGGCCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGCCTCTCCTAGGCCACTACAAACTGACCCCTCAGCAGGG
CTGGCTGCCACAGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCTGCTGCAGGGGGGTCTTGGGGAGAGTGGTGACTCCATT

>33366_33366_1_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000266014_PLXNB1_chr3_48445997_ENST00000296440_length(amino acids)=375AA_BP=308
MSFRKVNIIILVLAVALFLLVLHHNFLSLSSLLRNEVTDSGIVGPQPIDFVPNALRHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHN
TRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDI
LALYNTALKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNV
EEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLDHHCPGGGWHGPEDAAGLSAPADCSCCGKQGHRSIGTQEPRPAVASAWPGQP

--------------------------------------------------------------
>33366_33366_2_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000266014_PLXNB1_chr3_48445997_ENST00000358459_length(transcript)=2283nt_BP=1547nt
GCGCTTTTGCCGCGCCGTGCTGCCCGCGAGGGCAGCTGAGGTGGTGGTGGCGGCCGCCTTGTCGAGGCATCGCGCGCCCGTGAAGTGTTC
GCCGTCAGTGCTGTTGGGTGCCTGGAGCCGCGTCCCCCGTCCCGAAAACTGTCCTTGACAGTACTTGCGCGGCCCAACGGCCGCCGGCGC
CCCCGCGTCTCCATGGCGACGGCCTTTTTCCCTGCGAGGACCCCGGCGGCAGGGCTGCCCCGCGGCGCCTGCTTGGCGCGACGCTCTAGC
GGTTACCGCTGCGGGCTGGCTGGGCGTAGTGGGGCTGCGCGGCTGCCACGGAGCTAGAGGGCAAGTGTGCTCGGCCCAGCGTGCAGGGAA
CGCGGGCGGCCAGACAACGGGCTGGGCTCCGGGGCCTGCGGCGCGGGCGCTGAGCTGGCAGGGCGGGTCGGGGCGCGGGCTGCATCCGCA
TCTCCTCCATCGCCTGCAGTAAGGGCGGCCGCGGCGAGCCTTTGAGGGGAACGACTTGTCGGAGCCCTAACCAGGGGTATCTCTGAGCCT
GGTGGGATCCCCGGAGCGTCACATCACTTTCCGATCACTTCAAAGTGGTTAAAAACTAATATTTATATGACAGAAGAAAAAGATGTCATT
CCGTAAAGTAAACATCATCATCTTGGTCCTGGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAACTTCCTCAGCTTGAGCAGTTTGTT
AAGGAATGAGGTTACAGATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACA
AGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGCTC
CAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGGTCCTGGCTCAACAGTGATTCCCTGAAAAGCATCAGATA
CAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGACCAGGGGGAATCCATGAAACCTTTAACCTTTGC
AAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTGATATTCTTGCCCT
TTACAATACAGCACTGAAGCCAGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGG
AAACCAGTACAATTACATTGGCTATCTTGACTATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCC
TGGAGTTTTTGTTGCAAACCTGACGGAATGGAAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAAGAGGG
ACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTCCTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTG
GAATGTCCGCCACCTTGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGCAG
CTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTGCTGTTGCTTCAGCCTGGCCTGGGCAGCCCTGGAAGCT
CGGAGGAGAGGCCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAGTGGAAGGTGACTCCCAGTCTCCTGGTGGCTCTGGCCT
CGGCCCTGCTGGATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAGTACCCAGCCTGCTCCCCGAGTCCAGCGACCCTGTGAC
ACCGGTCTGCAGGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAGACTCCAGGCCCCTGGGGAGACTGTACTGTTCCTGAAC
ACTGGCCTTGGCCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTTCCTGTCTGCCTCCTCCACCATCCCTGACCTCAGTTGA
GCTGCCTCTGGCCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGCCTCTCCTAGGCCACTACAAACTGACCCCTCAGCAGGG
CTGGCTGCCACAGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCTGCTGCAGGGGGGTCTTGGGGAGAGTGGTGACTCCATT

>33366_33366_2_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000266014_PLXNB1_chr3_48445997_ENST00000358459_length(amino acids)=375AA_BP=308
MSFRKVNIIILVLAVALFLLVLHHNFLSLSSLLRNEVTDSGIVGPQPIDFVPNALRHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHN
TRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDI
LALYNTALKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNV
EEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLDHHCPGGGWHGPEDAAGLSAPADCSCCGKQGHRSIGTQEPRPAVASAWPGQP

--------------------------------------------------------------
>33366_33366_3_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000266014_PLXNB1_chr3_48445997_ENST00000358536_length(transcript)=2282nt_BP=1547nt
GCGCTTTTGCCGCGCCGTGCTGCCCGCGAGGGCAGCTGAGGTGGTGGTGGCGGCCGCCTTGTCGAGGCATCGCGCGCCCGTGAAGTGTTC
GCCGTCAGTGCTGTTGGGTGCCTGGAGCCGCGTCCCCCGTCCCGAAAACTGTCCTTGACAGTACTTGCGCGGCCCAACGGCCGCCGGCGC
CCCCGCGTCTCCATGGCGACGGCCTTTTTCCCTGCGAGGACCCCGGCGGCAGGGCTGCCCCGCGGCGCCTGCTTGGCGCGACGCTCTAGC
GGTTACCGCTGCGGGCTGGCTGGGCGTAGTGGGGCTGCGCGGCTGCCACGGAGCTAGAGGGCAAGTGTGCTCGGCCCAGCGTGCAGGGAA
CGCGGGCGGCCAGACAACGGGCTGGGCTCCGGGGCCTGCGGCGCGGGCGCTGAGCTGGCAGGGCGGGTCGGGGCGCGGGCTGCATCCGCA
TCTCCTCCATCGCCTGCAGTAAGGGCGGCCGCGGCGAGCCTTTGAGGGGAACGACTTGTCGGAGCCCTAACCAGGGGTATCTCTGAGCCT
GGTGGGATCCCCGGAGCGTCACATCACTTTCCGATCACTTCAAAGTGGTTAAAAACTAATATTTATATGACAGAAGAAAAAGATGTCATT
CCGTAAAGTAAACATCATCATCTTGGTCCTGGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAACTTCCTCAGCTTGAGCAGTTTGTT
AAGGAATGAGGTTACAGATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACA
AGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGCTC
CAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGGTCCTGGCTCAACAGTGATTCCCTGAAAAGCATCAGATA
CAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGACCAGGGGGAATCCATGAAACCTTTAACCTTTGC
AAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTGATATTCTTGCCCT
TTACAATACAGCACTGAAGCCAGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGG
AAACCAGTACAATTACATTGGCTATCTTGACTATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCC
TGGAGTTTTTGTTGCAAACCTGACGGAATGGAAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAAGAGGG
ACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTCCTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTG
GAATGTCCGCCACCTTGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGCAG
CTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTGCTGTTGCTTCAGCCTGGCCTGGGCAGCCCTGGAAGCT
CGGAGGAGAGGCCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAGTGGAAGGTGACTCCCAGTCTCCTGGTGGCTCTGGCCT
CGGCCCTGCTGGATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAGTACCCAGCCTGCTCCCCGAGTCCAGCGACCCTGTGAC
ACCGGTCTGCAGGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAGACTCCAGGCCCCTGGGGAGACTGTACTGTTCCTGAAC
ACTGGCCTTGGCCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTTCCTGTCTGCCTCCTCCACCATCCCTGACCTCAGTTGA
GCTGCCTCTGGCCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGCCTCTCCTAGGCCACTACAAACTGACCCCTCAGCAGGG
CTGGCTGCCACAGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCTGCTGCAGGGGGGTCTTGGGGAGAGTGGTGACTCCATT

>33366_33366_3_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000266014_PLXNB1_chr3_48445997_ENST00000358536_length(amino acids)=375AA_BP=308
MSFRKVNIIILVLAVALFLLVLHHNFLSLSSLLRNEVTDSGIVGPQPIDFVPNALRHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHN
TRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDI
LALYNTALKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNV
EEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLDHHCPGGGWHGPEDAAGLSAPADCSCCGKQGHRSIGTQEPRPAVASAWPGQP

--------------------------------------------------------------
>33366_33366_4_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000407584_PLXNB1_chr3_48445997_ENST00000448774_length(transcript)=1922nt_BP=1776nt
GCGCTTTTGCCGCGCCGTGCTGCCCGCGAGGGCAGCTGAGGTGGTGGTGGCGGCCGCCTTGTCGAGGCATCGCGCGCCCGTGAAGTGTTC
GCCGTCAGTGCTGTTGGGTGCCTGGAGCCGCGTCCCCCGTCCCGAAAACTGTCCTTGACAGTACTTGCGCGGCCCAACGGCCGCCGGCGC
CCCCGCGTCTCCATGGCGACGGCCTTTTTCCCTGCGAGGACCCCGGCGGCAGGGCTGCCCCGCGGCGCCTGCTTGGCGCGACGCTCTAGC
GGTTACCGCTGCGGGCTGGCTGGGCGTAGTGGGGCTGCGCGGCTGCCACGGAGCTAGAGGGCAAGTGTGCTCGGCCCAGCGTGCAGGGAA
CGCGGGCGGCCAGACAACGGGCTGGGCTCCGGGGCCTGCGGCGCGGGCGCTGAGCTGGCAGGGCGGGTCGGGGCGCGGGCTGCATCCGCA
TCTCCTCCATCGCCTGCAGTAAGGGCGGCCGCGGCGAGCCTTTGAGGGGAACGACTTGTCGGAGCCCTAACCAGGGGTATCTCTGAGCCT
GGTGGGATCCCCGGAGCGTCACATCACTTTCCGATCACTTCAAAGTACAGCAGACCGAGGACACGGTTGTTACCAAGACCAGGCTGTTGC
CTTGGAAGAGCCCAGAGCGTGTCAAGGGAGACAGCCACATCACGCCAGAAATACATGACAGCTGGATTAGCCCTGGGAGAGGGAGGCCCA
GATGTGGGAGCTCAGGGGAGGTGCAGCTCAACGTGGAGTTTGGAGGAGGCTACCTTGACCTTTGAATGCCAAGTGGGAGCCAGCCAGATG
AAAGGGGTTAAAAACTAATATTTATATGACAGAAGAAAAAGATGTCATTCCGTAAAGTAAACATCATCATCTTGGTCCTGGCTGTTGCTC
TCTTCTTACTGGTTTTGCACCATAACTTCCTCAGCTTGAGCAGTTTGTTAAGGAATGAGGTTACAGATTCAGGAATTGTAGGGCCTCAAC
CTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACAAGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGC
TTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGCTCCAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAG
ACCATCTCCGGTCCTGGCTCAACAGTGATTCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAG
TAAAGGAGGATCCTGACCAGGGGGAATCCATGAAACCTTTAACCTTTGCAAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGG
CCATATACATGGATGATGATGTAATTGTGCAAGGTGATATTCTTGCCCTTTACAATACAGCACTGAAGCCAGGACATGCAGCTGCATTTT
CAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTACAATTACATTGGCTATCTTGACTATAAAAAGG
AAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAACCTGACGGAATGGAAACGACAGA
ATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTC
CTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGATCATCACTGCCCTGGAGGAGGAT
GGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGCAGCTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGG

>33366_33366_4_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000407584_PLXNB1_chr3_48445997_ENST00000448774_length(amino acids)=357AA_BP=308
MSFRKVNIIILVLAVALFLLVLHHNFLSLSSLLRNEVTDSGIVGPQPIDFVPNALRHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHN
TRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDI
LALYNTALKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNV

--------------------------------------------------------------
>33366_33366_5_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000407584_PLXNB1_chr3_48445997_ENST00000456774_length(transcript)=1881nt_BP=1776nt
GCGCTTTTGCCGCGCCGTGCTGCCCGCGAGGGCAGCTGAGGTGGTGGTGGCGGCCGCCTTGTCGAGGCATCGCGCGCCCGTGAAGTGTTC
GCCGTCAGTGCTGTTGGGTGCCTGGAGCCGCGTCCCCCGTCCCGAAAACTGTCCTTGACAGTACTTGCGCGGCCCAACGGCCGCCGGCGC
CCCCGCGTCTCCATGGCGACGGCCTTTTTCCCTGCGAGGACCCCGGCGGCAGGGCTGCCCCGCGGCGCCTGCTTGGCGCGACGCTCTAGC
GGTTACCGCTGCGGGCTGGCTGGGCGTAGTGGGGCTGCGCGGCTGCCACGGAGCTAGAGGGCAAGTGTGCTCGGCCCAGCGTGCAGGGAA
CGCGGGCGGCCAGACAACGGGCTGGGCTCCGGGGCCTGCGGCGCGGGCGCTGAGCTGGCAGGGCGGGTCGGGGCGCGGGCTGCATCCGCA
TCTCCTCCATCGCCTGCAGTAAGGGCGGCCGCGGCGAGCCTTTGAGGGGAACGACTTGTCGGAGCCCTAACCAGGGGTATCTCTGAGCCT
GGTGGGATCCCCGGAGCGTCACATCACTTTCCGATCACTTCAAAGTACAGCAGACCGAGGACACGGTTGTTACCAAGACCAGGCTGTTGC
CTTGGAAGAGCCCAGAGCGTGTCAAGGGAGACAGCCACATCACGCCAGAAATACATGACAGCTGGATTAGCCCTGGGAGAGGGAGGCCCA
GATGTGGGAGCTCAGGGGAGGTGCAGCTCAACGTGGAGTTTGGAGGAGGCTACCTTGACCTTTGAATGCCAAGTGGGAGCCAGCCAGATG
AAAGGGGTTAAAAACTAATATTTATATGACAGAAGAAAAAGATGTCATTCCGTAAAGTAAACATCATCATCTTGGTCCTGGCTGTTGCTC
TCTTCTTACTGGTTTTGCACCATAACTTCCTCAGCTTGAGCAGTTTGTTAAGGAATGAGGTTACAGATTCAGGAATTGTAGGGCCTCAAC
CTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACAAGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGC
TTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGCTCCAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAG
ACCATCTCCGGTCCTGGCTCAACAGTGATTCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAG
TAAAGGAGGATCCTGACCAGGGGGAATCCATGAAACCTTTAACCTTTGCAAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGG
CCATATACATGGATGATGATGTAATTGTGCAAGGTGATATTCTTGCCCTTTACAATACAGCACTGAAGCCAGGACATGCAGCTGCATTTT
CAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTACAATTACATTGGCTATCTTGACTATAAAAAGG
AAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAACCTGACGGAATGGAAACGACAGA
ATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTC
CTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGATCATCACTGCCCTGGAGGAGGAT

>33366_33366_5_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000407584_PLXNB1_chr3_48445997_ENST00000456774_length(amino acids)=343AA_BP=308
MSFRKVNIIILVLAVALFLLVLHHNFLSLSSLLRNEVTDSGIVGPQPIDFVPNALRHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHN
TRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDI
LALYNTALKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNV

--------------------------------------------------------------
>33366_33366_6_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000478968_PLXNB1_chr3_48445997_ENST00000296440_length(transcript)=2016nt_BP=1279nt
GCGGCGCCTGCTTGGCGCGACGCTCTAGCGGTTACCGCTGCGGGCTGGCTGGGCGTAGTGGGGCTGCGCGGCTGCCACGGAGCTAGAGGA
CAGCAGACCGAGGACACGGTTGTTACCAAGACCAGGCTGTTGCCTTGGAAGAGCCCAGAGCGTGTCAAGGGAGACAGCCACATCACGCCA
GAAATACATGACAGCTGGATTAGCCCTGGGAGAGGGAGGCCCAGATGTGGGAGCTCAGGGGAGGTGCAGCTCAACGTGGAGTTTGGAGGA
GGCTACCTTGACCTTTGAATGCCAAGTGGGAGCCAGCCAGATGAAAGGGGTTAAAAACTAATATTTATATGACAGAAGAAAAAGATGTCA
TTCCGTAAAGTAAACATCATCATCTTGGTCCTGGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAACTTCCTCAGCTTGAGCAGTTTG
TTAAGGAATGAGGTTACAGATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGA
CAAGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGC
TCCAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGGTCCTGGCTCAACAGTGATTCCCTGAAAAGCATCAGA
TACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGACCAGGGGGAATCCATGAAACCTTTAACCTTT
GCAAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTGATATTCTTGCC
CTTTACAATACAGCACTGAAGCCAGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCA
GGAAACCAGTACAATTACATTGGCTATCTTGACTATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAAT
CCTGGAGTTTTTGTTGCAAACCTGACGGAATGGAAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAAGAG
GGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTCCTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATG
TGGAATGTCCGCCACCTTGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGC
AGCTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTGCTGTTGCTTCAGCCTGGCCTGGGCAGCCCTGGAAG
CTCGGAGGAGAGGCCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAGTGGAAGGTGACTCCCAGTCTCCTGGTGGCTCTGGC
CTCGGCCCTGCTGGATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAGTACCCAGCCTGCTCCCCGAGTCCAGCGACCCTGTG
ACACCGGTCTGCAGGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAGACTCCAGGCCCCTGGGGAGACTGTACTGTTCCTGA
ACACTGGCCTTGGCCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTTCCTGTCTGCCTCCTCCACCATCCCTGACCTCAGTT
GAGCTGCCTCTGGCCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGCCTCTCCTAGGCCACTACAAACTGACCCCTCAGCAG
GGCTGGCTGCCACAGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCTGCTGCAGGGGGGTCTTGGGGAGAGTGGTGACTCCA

>33366_33366_6_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000478968_PLXNB1_chr3_48445997_ENST00000296440_length(amino acids)=375AA_BP=308
MSFRKVNIIILVLAVALFLLVLHHNFLSLSSLLRNEVTDSGIVGPQPIDFVPNALRHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHN
TRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDI
LALYNTALKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNV
EEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLDHHCPGGGWHGPEDAAGLSAPADCSCCGKQGHRSIGTQEPRPAVASAWPGQP

--------------------------------------------------------------
>33366_33366_7_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000478968_PLXNB1_chr3_48445997_ENST00000358459_length(transcript)=2015nt_BP=1279nt
GCGGCGCCTGCTTGGCGCGACGCTCTAGCGGTTACCGCTGCGGGCTGGCTGGGCGTAGTGGGGCTGCGCGGCTGCCACGGAGCTAGAGGA
CAGCAGACCGAGGACACGGTTGTTACCAAGACCAGGCTGTTGCCTTGGAAGAGCCCAGAGCGTGTCAAGGGAGACAGCCACATCACGCCA
GAAATACATGACAGCTGGATTAGCCCTGGGAGAGGGAGGCCCAGATGTGGGAGCTCAGGGGAGGTGCAGCTCAACGTGGAGTTTGGAGGA
GGCTACCTTGACCTTTGAATGCCAAGTGGGAGCCAGCCAGATGAAAGGGGTTAAAAACTAATATTTATATGACAGAAGAAAAAGATGTCA
TTCCGTAAAGTAAACATCATCATCTTGGTCCTGGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAACTTCCTCAGCTTGAGCAGTTTG
TTAAGGAATGAGGTTACAGATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGA
CAAGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGC
TCCAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGGTCCTGGCTCAACAGTGATTCCCTGAAAAGCATCAGA
TACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGACCAGGGGGAATCCATGAAACCTTTAACCTTT
GCAAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTGATATTCTTGCC
CTTTACAATACAGCACTGAAGCCAGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCA
GGAAACCAGTACAATTACATTGGCTATCTTGACTATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAAT
CCTGGAGTTTTTGTTGCAAACCTGACGGAATGGAAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAAGAG
GGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTCCTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATG
TGGAATGTCCGCCACCTTGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGC
AGCTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTGCTGTTGCTTCAGCCTGGCCTGGGCAGCCCTGGAAG
CTCGGAGGAGAGGCCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAGTGGAAGGTGACTCCCAGTCTCCTGGTGGCTCTGGC
CTCGGCCCTGCTGGATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAGTACCCAGCCTGCTCCCCGAGTCCAGCGACCCTGTG
ACACCGGTCTGCAGGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAGACTCCAGGCCCCTGGGGAGACTGTACTGTTCCTGA
ACACTGGCCTTGGCCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTTCCTGTCTGCCTCCTCCACCATCCCTGACCTCAGTT
GAGCTGCCTCTGGCCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGCCTCTCCTAGGCCACTACAAACTGACCCCTCAGCAG
GGCTGGCTGCCACAGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCTGCTGCAGGGGGGTCTTGGGGAGAGTGGTGACTCCA

>33366_33366_7_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000478968_PLXNB1_chr3_48445997_ENST00000358459_length(amino acids)=375AA_BP=308
MSFRKVNIIILVLAVALFLLVLHHNFLSLSSLLRNEVTDSGIVGPQPIDFVPNALRHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHN
TRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDI
LALYNTALKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNV
EEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLDHHCPGGGWHGPEDAAGLSAPADCSCCGKQGHRSIGTQEPRPAVASAWPGQP

--------------------------------------------------------------
>33366_33366_8_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000478968_PLXNB1_chr3_48445997_ENST00000358536_length(transcript)=2014nt_BP=1279nt
GCGGCGCCTGCTTGGCGCGACGCTCTAGCGGTTACCGCTGCGGGCTGGCTGGGCGTAGTGGGGCTGCGCGGCTGCCACGGAGCTAGAGGA
CAGCAGACCGAGGACACGGTTGTTACCAAGACCAGGCTGTTGCCTTGGAAGAGCCCAGAGCGTGTCAAGGGAGACAGCCACATCACGCCA
GAAATACATGACAGCTGGATTAGCCCTGGGAGAGGGAGGCCCAGATGTGGGAGCTCAGGGGAGGTGCAGCTCAACGTGGAGTTTGGAGGA
GGCTACCTTGACCTTTGAATGCCAAGTGGGAGCCAGCCAGATGAAAGGGGTTAAAAACTAATATTTATATGACAGAAGAAAAAGATGTCA
TTCCGTAAAGTAAACATCATCATCTTGGTCCTGGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAACTTCCTCAGCTTGAGCAGTTTG
TTAAGGAATGAGGTTACAGATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGA
CAAGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGC
TCCAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGGTCCTGGCTCAACAGTGATTCCCTGAAAAGCATCAGA
TACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGACCAGGGGGAATCCATGAAACCTTTAACCTTT
GCAAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTGATATTCTTGCC
CTTTACAATACAGCACTGAAGCCAGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCA
GGAAACCAGTACAATTACATTGGCTATCTTGACTATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAAT
CCTGGAGTTTTTGTTGCAAACCTGACGGAATGGAAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAAGAG
GGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTCCTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATG
TGGAATGTCCGCCACCTTGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGC
AGCTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTGCTGTTGCTTCAGCCTGGCCTGGGCAGCCCTGGAAG
CTCGGAGGAGAGGCCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAGTGGAAGGTGACTCCCAGTCTCCTGGTGGCTCTGGC
CTCGGCCCTGCTGGATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAGTACCCAGCCTGCTCCCCGAGTCCAGCGACCCTGTG
ACACCGGTCTGCAGGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAGACTCCAGGCCCCTGGGGAGACTGTACTGTTCCTGA
ACACTGGCCTTGGCCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTTCCTGTCTGCCTCCTCCACCATCCCTGACCTCAGTT
GAGCTGCCTCTGGCCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGCCTCTCCTAGGCCACTACAAACTGACCCCTCAGCAG
GGCTGGCTGCCACAGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCTGCTGCAGGGGGGTCTTGGGGAGAGTGGTGACTCCA

>33366_33366_8_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000478968_PLXNB1_chr3_48445997_ENST00000358536_length(amino acids)=375AA_BP=308
MSFRKVNIIILVLAVALFLLVLHHNFLSLSSLLRNEVTDSGIVGPQPIDFVPNALRHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHN
TRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDI
LALYNTALKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNV
EEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLDHHCPGGGWHGPEDAAGLSAPADCSCCGKQGHRSIGTQEPRPAVASAWPGQP

--------------------------------------------------------------
>33366_33366_9_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000491606_PLXNB1_chr3_48445997_ENST00000296440_length(transcript)=1781nt_BP=1044nt
CTTGGCGCGACGCTCTAGCGGTTACCGCTGCGGGCTGGCTGGGCGTAGTGGGGCTGCGCGGCTGCCACGGAGCTAGAGGGCAAGGTTAAA
AACTAATATTTATATGACAGAAGAAAAAGATGTCATTCCGTAAAGTAAACATCATCATCTTGGTCCTGGCTGTTGCTCTCTTCTTACTGG
TTTTGCACCATAACTTCCTCAGCTTGAGCAGTTTGTTAAGGAATGAGGTTACAGATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTG
TCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACAAGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCA
TTGCAGCTATAAACAGCATTCAGCACAACACTCGCTCCAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGGT
CCTGGCTCAACAGTGATTCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATC
CTGACCAGGGGGAATCCATGAAACCTTTAACCTTTGCAAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGG
ATGATGATGTAATTGTGCAAGGTGATATTCTTGCCCTTTACAATACAGCACTGAAGCCAGGACATGCAGCTGCATTTTCAGAAGATTGTG
ATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTACAATTACATTGGCTATCTTGACTATAAAAAGGAAAGAATTCGTA
AGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAACCTGACGGAATGGAAACGACAGAATATAACTAACC
AACTGGAAAAATGGATGAAACTCAATGTAGAAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTCCTCTGCTTATCG
TATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAG
AAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGCAGCTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTG
CTGTTGCTTCAGCCTGGCCTGGGCAGCCCTGGAAGCTCGGAGGAGAGGCCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAG
TGGAAGGTGACTCCCAGTCTCCTGGTGGCTCTGGCCTCGGCCCTGCTGGATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAG
TACCCAGCCTGCTCCCCGAGTCCAGCGACCCTGTGACACCGGTCTGCAGGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAG
ACTCCAGGCCCCTGGGGAGACTGTACTGTTCCTGAACACTGGCCTTGGCCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTT
CCTGTCTGCCTCCTCCACCATCCCTGACCTCAGTTGAGCTGCCTCTGGCCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGC
CTCTCCTAGGCCACTACAAACTGACCCCTCAGCAGGGCTGGCTGCCACAGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCT

>33366_33366_9_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000491606_PLXNB1_chr3_48445997_ENST00000296440_length(amino acids)=375AA_BP=308
MSFRKVNIIILVLAVALFLLVLHHNFLSLSSLLRNEVTDSGIVGPQPIDFVPNALRHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHN
TRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDI
LALYNTALKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNV
EEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLDHHCPGGGWHGPEDAAGLSAPADCSCCGKQGHRSIGTQEPRPAVASAWPGQP

--------------------------------------------------------------
>33366_33366_10_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000491606_PLXNB1_chr3_48445997_ENST00000358459_length(transcript)=1780nt_BP=1044nt
CTTGGCGCGACGCTCTAGCGGTTACCGCTGCGGGCTGGCTGGGCGTAGTGGGGCTGCGCGGCTGCCACGGAGCTAGAGGGCAAGGTTAAA
AACTAATATTTATATGACAGAAGAAAAAGATGTCATTCCGTAAAGTAAACATCATCATCTTGGTCCTGGCTGTTGCTCTCTTCTTACTGG
TTTTGCACCATAACTTCCTCAGCTTGAGCAGTTTGTTAAGGAATGAGGTTACAGATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTG
TCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACAAGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCA
TTGCAGCTATAAACAGCATTCAGCACAACACTCGCTCCAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGGT
CCTGGCTCAACAGTGATTCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATC
CTGACCAGGGGGAATCCATGAAACCTTTAACCTTTGCAAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGG
ATGATGATGTAATTGTGCAAGGTGATATTCTTGCCCTTTACAATACAGCACTGAAGCCAGGACATGCAGCTGCATTTTCAGAAGATTGTG
ATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTACAATTACATTGGCTATCTTGACTATAAAAAGGAAAGAATTCGTA
AGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAACCTGACGGAATGGAAACGACAGAATATAACTAACC
AACTGGAAAAATGGATGAAACTCAATGTAGAAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTCCTCTGCTTATCG
TATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAG
AAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGCAGCTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTG
CTGTTGCTTCAGCCTGGCCTGGGCAGCCCTGGAAGCTCGGAGGAGAGGCCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAG
TGGAAGGTGACTCCCAGTCTCCTGGTGGCTCTGGCCTCGGCCCTGCTGGATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAG
TACCCAGCCTGCTCCCCGAGTCCAGCGACCCTGTGACACCGGTCTGCAGGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAG
ACTCCAGGCCCCTGGGGAGACTGTACTGTTCCTGAACACTGGCCTTGGCCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTT
CCTGTCTGCCTCCTCCACCATCCCTGACCTCAGTTGAGCTGCCTCTGGCCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGC
CTCTCCTAGGCCACTACAAACTGACCCCTCAGCAGGGCTGGCTGCCACAGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCT

>33366_33366_10_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000491606_PLXNB1_chr3_48445997_ENST00000358459_length(amino acids)=375AA_BP=308
MSFRKVNIIILVLAVALFLLVLHHNFLSLSSLLRNEVTDSGIVGPQPIDFVPNALRHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHN
TRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDI
LALYNTALKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNV
EEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLDHHCPGGGWHGPEDAAGLSAPADCSCCGKQGHRSIGTQEPRPAVASAWPGQP

--------------------------------------------------------------
>33366_33366_11_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000491606_PLXNB1_chr3_48445997_ENST00000358536_length(transcript)=1779nt_BP=1044nt
CTTGGCGCGACGCTCTAGCGGTTACCGCTGCGGGCTGGCTGGGCGTAGTGGGGCTGCGCGGCTGCCACGGAGCTAGAGGGCAAGGTTAAA
AACTAATATTTATATGACAGAAGAAAAAGATGTCATTCCGTAAAGTAAACATCATCATCTTGGTCCTGGCTGTTGCTCTCTTCTTACTGG
TTTTGCACCATAACTTCCTCAGCTTGAGCAGTTTGTTAAGGAATGAGGTTACAGATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTG
TCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACAAGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCA
TTGCAGCTATAAACAGCATTCAGCACAACACTCGCTCCAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGGT
CCTGGCTCAACAGTGATTCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATC
CTGACCAGGGGGAATCCATGAAACCTTTAACCTTTGCAAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGG
ATGATGATGTAATTGTGCAAGGTGATATTCTTGCCCTTTACAATACAGCACTGAAGCCAGGACATGCAGCTGCATTTTCAGAAGATTGTG
ATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTACAATTACATTGGCTATCTTGACTATAAAAAGGAAAGAATTCGTA
AGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAACCTGACGGAATGGAAACGACAGAATATAACTAACC
AACTGGAAAAATGGATGAAACTCAATGTAGAAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTCCTCTGCTTATCG
TATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAG
AAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGCAGCTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTG
CTGTTGCTTCAGCCTGGCCTGGGCAGCCCTGGAAGCTCGGAGGAGAGGCCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAG
TGGAAGGTGACTCCCAGTCTCCTGGTGGCTCTGGCCTCGGCCCTGCTGGATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAG
TACCCAGCCTGCTCCCCGAGTCCAGCGACCCTGTGACACCGGTCTGCAGGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAG
ACTCCAGGCCCCTGGGGAGACTGTACTGTTCCTGAACACTGGCCTTGGCCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTT
CCTGTCTGCCTCCTCCACCATCCCTGACCTCAGTTGAGCTGCCTCTGGCCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGC
CTCTCCTAGGCCACTACAAACTGACCCCTCAGCAGGGCTGGCTGCCACAGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCT

>33366_33366_11_GLT8D1-PLXNB1_GLT8D1_chr3_52729206_ENST00000491606_PLXNB1_chr3_48445997_ENST00000358536_length(amino acids)=375AA_BP=308
MSFRKVNIIILVLAVALFLLVLHHNFLSLSSLLRNEVTDSGIVGPQPIDFVPNALRHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHN
TRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDI
LALYNTALKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNV
EEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLDHHCPGGGWHGPEDAAGLSAPADCSCCGKQGHRSIGTQEPRPAVASAWPGQP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for GLT8D1-PLXNB1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GLT8D1-PLXNB1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GLT8D1-PLXNB1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource