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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GLUD1-MLPH (FusionGDB2 ID:33394)

Fusion Gene Summary for GLUD1-MLPH

check button Fusion gene summary
Fusion gene informationFusion gene name: GLUD1-MLPH
Fusion gene ID: 33394
HgeneTgene
Gene symbol

GLUD1

MLPH

Gene ID

2746

79083

Gene nameglutamate dehydrogenase 1melanophilin
SynonymsGDH|GDH1|GLUDSLAC2-A
Cytomap

10q23.2

2q37.3

Type of geneprotein-codingprotein-coding
Descriptionglutamate dehydrogenase 1, mitochondrialepididymis secretory sperm binding proteinepididymis tissue sperm binding protein Li 18mPglutamate dehydrogenase (NAD(P)+)melanophilinexophilin-3slp homolog lacking C2 domains asynaptotagmin-like protein 2a
Modification date2020032920200320
UniProtAcc

P00367

Q9BV36

Ensembl transtripts involved in fusion geneENST00000277865, ENST00000537649, 
ENST00000544149, ENST00000465164, 
ENST00000338530, ENST00000409373, 
ENST00000468178, ENST00000264605, 
ENST00000410032, ENST00000445024, 
Fusion gene scores* DoF score3 X 3 X 2=1812 X 13 X 9=1404
# samples 314
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(14/1404*10)=-3.32604420335959
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GLUD1 [Title/Abstract] AND MLPH [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGLUD1(88834308)-MLPH(238427182), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneGLUD1

GO:0006537

glutamate biosynthetic process

11032875

HgeneGLUD1

GO:0006538

glutamate catabolic process

6121377|11032875


check buttonFusion gene breakpoints across GLUD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MLPH (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-FP-8210-01AGLUD1chr10

88834308

-MLPHchr2

238427182

+


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Fusion Gene ORF analysis for GLUD1-MLPH

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000277865ENST00000338530GLUD1chr10

88834308

-MLPHchr2

238427182

+
5CDS-3UTRENST00000277865ENST00000409373GLUD1chr10

88834308

-MLPHchr2

238427182

+
5CDS-3UTRENST00000277865ENST00000468178GLUD1chr10

88834308

-MLPHchr2

238427182

+
5CDS-3UTRENST00000537649ENST00000338530GLUD1chr10

88834308

-MLPHchr2

238427182

+
5CDS-3UTRENST00000537649ENST00000409373GLUD1chr10

88834308

-MLPHchr2

238427182

+
5CDS-3UTRENST00000537649ENST00000468178GLUD1chr10

88834308

-MLPHchr2

238427182

+
5CDS-3UTRENST00000544149ENST00000338530GLUD1chr10

88834308

-MLPHchr2

238427182

+
5CDS-3UTRENST00000544149ENST00000409373GLUD1chr10

88834308

-MLPHchr2

238427182

+
5CDS-3UTRENST00000544149ENST00000468178GLUD1chr10

88834308

-MLPHchr2

238427182

+
In-frameENST00000277865ENST00000264605GLUD1chr10

88834308

-MLPHchr2

238427182

+
In-frameENST00000277865ENST00000410032GLUD1chr10

88834308

-MLPHchr2

238427182

+
In-frameENST00000277865ENST00000445024GLUD1chr10

88834308

-MLPHchr2

238427182

+
In-frameENST00000537649ENST00000264605GLUD1chr10

88834308

-MLPHchr2

238427182

+
In-frameENST00000537649ENST00000410032GLUD1chr10

88834308

-MLPHchr2

238427182

+
In-frameENST00000537649ENST00000445024GLUD1chr10

88834308

-MLPHchr2

238427182

+
In-frameENST00000544149ENST00000264605GLUD1chr10

88834308

-MLPHchr2

238427182

+
In-frameENST00000544149ENST00000410032GLUD1chr10

88834308

-MLPHchr2

238427182

+
In-frameENST00000544149ENST00000445024GLUD1chr10

88834308

-MLPHchr2

238427182

+
intron-3CDSENST00000465164ENST00000264605GLUD1chr10

88834308

-MLPHchr2

238427182

+
intron-3CDSENST00000465164ENST00000410032GLUD1chr10

88834308

-MLPHchr2

238427182

+
intron-3CDSENST00000465164ENST00000445024GLUD1chr10

88834308

-MLPHchr2

238427182

+
intron-3UTRENST00000465164ENST00000338530GLUD1chr10

88834308

-MLPHchr2

238427182

+
intron-3UTRENST00000465164ENST00000409373GLUD1chr10

88834308

-MLPHchr2

238427182

+
intron-3UTRENST00000465164ENST00000468178GLUD1chr10

88834308

-MLPHchr2

238427182

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000277865GLUD1chr1088834308-ENST00000410032MLPHchr2238427182+2076743971671524
ENST00000277865GLUD1chr1088834308-ENST00000264605MLPHchr2238427182+3827743972100667
ENST00000277865GLUD1chr1088834308-ENST00000445024MLPHchr2238427182+2360743971953618
ENST00000537649GLUD1chr1088834308-ENST00000410032MLPHchr2238427182+20256924571620387
ENST00000537649GLUD1chr1088834308-ENST00000264605MLPHchr2238427182+37766924572049530
ENST00000537649GLUD1chr1088834308-ENST00000445024MLPHchr2238427182+23096924571902481
ENST00000544149GLUD1chr1088834308-ENST00000410032MLPHchr2238427182+1689356311284417
ENST00000544149GLUD1chr1088834308-ENST00000264605MLPHchr2238427182+3440356311713560
ENST00000544149GLUD1chr1088834308-ENST00000445024MLPHchr2238427182+1973356311566511

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000277865ENST00000410032GLUD1chr1088834308-MLPHchr2238427182+0.0044196010.9955804
ENST00000277865ENST00000264605GLUD1chr1088834308-MLPHchr2238427182+0.005484320.9945156
ENST00000277865ENST00000445024GLUD1chr1088834308-MLPHchr2238427182+0.012930030.98706996
ENST00000537649ENST00000410032GLUD1chr1088834308-MLPHchr2238427182+0.0013796170.9986204
ENST00000537649ENST00000264605GLUD1chr1088834308-MLPHchr2238427182+0.0016565860.99834335
ENST00000537649ENST00000445024GLUD1chr1088834308-MLPHchr2238427182+0.003593790.99640614
ENST00000544149ENST00000410032GLUD1chr1088834308-MLPHchr2238427182+0.00697870.9930213
ENST00000544149ENST00000264605GLUD1chr1088834308-MLPHchr2238427182+0.004828040.99517196
ENST00000544149ENST00000445024GLUD1chr1088834308-MLPHchr2238427182+0.0095108170.9904891

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Fusion Genomic Features for GLUD1-MLPH


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
GLUD1chr1088834307-MLPHchr2238427181+5.30E-070.9999995
GLUD1chr1088834307-MLPHchr2238427181+5.30E-070.9999995

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for GLUD1-MLPH


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:88834308/chr2:238427182)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GLUD1

P00367

MLPH

Q9BV36

FUNCTION: Mitochondrial glutamate dehydrogenase that catalyzes the conversion of L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle (PubMed:11032875, PubMed:16959573, PubMed:11254391, PubMed:16023112). Plays a role in insulin homeostasis (PubMed:9571255, PubMed:11297618). May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity). {ECO:0000250|UniProtKB:P10860, ECO:0000269|PubMed:11032875, ECO:0000269|PubMed:11254391, ECO:0000269|PubMed:11297618, ECO:0000269|PubMed:16023112, ECO:0000269|PubMed:16959573, ECO:0000269|PubMed:9571255}.FUNCTION: Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor protein MYO5A. {ECO:0000269|PubMed:12062444}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGLUD1chr10:88834308chr2:238427182ENST00000277865-413141_143215559.0Nucleotide bindingNAD
TgeneMLPHchr10:88834308chr2:238427182ENST00000264605316373_496148601.0Coiled coilOntology_term=ECO:0000255
TgeneMLPHchr10:88834308chr2:238427182ENST00000338530315373_496148573.0Coiled coilOntology_term=ECO:0000255
TgeneMLPHchr10:88834308chr2:238427182ENST00000409373313373_496148481.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMLPHchr10:88834308chr2:238427182ENST000002646053164_124148601.0DomainRabBD
TgeneMLPHchr10:88834308chr2:238427182ENST000003385303154_124148573.0DomainRabBD
TgeneMLPHchr10:88834308chr2:238427182ENST000004093733134_124148481.0DomainRabBD
TgeneMLPHchr10:88834308chr2:238427182ENST0000026460531664_107148601.0Zinc fingerNote=FYVE-type
TgeneMLPHchr10:88834308chr2:238427182ENST0000033853031564_107148573.0Zinc fingerNote=FYVE-type
TgeneMLPHchr10:88834308chr2:238427182ENST0000040937331364_107148481.0Zinc fingerNote=FYVE-type


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Fusion Gene Sequence for GLUD1-MLPH


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>33394_33394_1_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000277865_MLPH_chr2_238427182_ENST00000264605_length(transcript)=3827nt_BP=743nt
GGGCAACCCGCGCGGGACCCTTCCTCCCTAGTCGCGGGGAGTCTGAGAAAGCGCGCCTGTTTCGCGACCATCACGCACCTCCCCTCCGCT
TGTGGCCATGTACCGCTACCTGGGCGAAGCGCTGTTGCTGTCCCGGGCCGGGCCCGCTGCCCTGGGCTCGGCGTCCGCCGACTCGGCCGC
GTTGCTGGGCTGGGCCCGGGGACAGCCCGCCGCCGCCCCGCAGCCGGGGCTGGCATTGGCCGCCCGGCGCCACTACAGCGAGGCGGTGGC
CGACCGCGAGGACGACCCCAACTTCTTCAAGATGGTGGAGGGCTTCTTCGATCGCGGCGCCAGCATCGTGGAGGACAAGCTGGTGGAGGA
CCTGAGGACCCGGGAGAGCGAGGAGCAGAAGCGGAACCGGGTGCGCGGCATCCTGCGGATCATCAAGCCCTGCAACCATGTGCTGAGTCT
CTCCTTCCCCATCCGGCGCGACGACGGCTCCTGGGAGGTCATCGAAGGCTACCGGGCCCAGCACAGCCAGCACCGCACGCCCTGCAAGGG
AGGTATCCGTTACAGCACTGATGTGAGTGTAGATGAAGTAAAAGCTTTGGCTTCTCTGATGACATACAAGTGTGCAGTGGTTGATGTGCC
GTTTGGGGGTGCTAAAGCTGGTGTTAAGATCAATCCCAAGAACTATACTGATAATGAATTGGAAAAGATCACAAGGAGGTTCACCATGGA
GCTAGCAAAAAAGGGCTTTATTGCTGGGCCTGAACTGATATCTGAAGAGAGAAGTGGAGACAGCGACCAGACAGATGAGGATGGAGAACC
TGGCTCAGAGGCCCAGGCCCAGGCCCAGCCCTTTGGCAGCAAAAAAAAGCGCCTCCTCTCCGTCCACGACTTCGACTTCGAGGGAGACTC
AGATGACTCCACTCAGCCTCAAGGTCACTCCCTGCACCTGTCCTCAGTCCCTGAGGCCAGGGACAGCCCACAGTCCCTCACAGATGAGTC
CTGCTCAGAGAAGGCAGCCCCTCACAAGGCTGAGGGCCTGGAGGAGGCTGATACTGGGGCCTCTGGGTGCCACTCCCATCCGGAAGAGCA
GCCGACCAGCATCTCACCTTCCAGACACGGCGCCCTGGCTGAGCTCTGCCCGCCTGGAGGCTCCCACAGGATGGCCCTGGGGACTGCTGC
TGCACTCGGGTCGAATGTCATCAGGAATGAGCAGCTGCCCCTGCAGTACTTGGCCGATGTGGACACCTCTGATGAGGAAAGCATCCGGGC
TCACGTGATGGCCTCCCACCATTCCAAGCGGAGAGGCCGGGCGTCTTCTGAGAGTCAGATCTTTGAGCTGAATAAGCATATTTCAGCTGT
GGAATGCCTGCTGACCTACCTGGAGAACACAGTTGTGCCTCCCTTGGCCAAGGGTCTAGGTGCTGGAGTGCGCACGGAGGCCGATGTAGA
GGAGGAGGCCCTGAGGAGGAAGCTGGAGGAGCTGACCAGCAACGTCAGTGACCAGGAGACCTCGTCCGAGGAGGAGGAAGCCAAGGACGA
AAAGGCAGAGCCCAACAGGGACAAATCAGTTGGGCCTCTCCCCCAGGCGGACCCGGAGGTGGGCACGGCTGCCCATCAAACCAACAGACA
GGAAAAAAGCCCCCAGGACCCTGGGGACCCCGTCCAGTACAACAGGACCACAGATGAGGAGCTGTCAGAGCTGGAGGACAGAGTGGCAGT
GACGGCCTCAGAAGTCCAGCAGGCAGAGAGCGAGGTTTCAGACATTGAATCCAGGATTGCAGCCCTGAGGGCCGCAGGGCTCACGGTGAA
GCCCTCGGGAAAGCCCCGGAGGAAGTCAAACCTCCCGATATTTCTCCCTCGAGTGGCTGGGAAACTTGGCAAGAGACCAGAGGACCCAAA
TGCAGACCCTTCAAGTGAGGCCAAGGCAATGGCTGTGCCCTATCTTCTGAGAAGAAAGTTCAGTAATTCCCTGAAAAGTCAAGGTAAAGA
TGATGATTCTTTTGATCGGAAATCAGTGTACCGAGGCTCGCTGACACAGAGAAACCCCAACGCGAGGAAAGGAATGGCCAGCCACACCTT
CGCGAAACCTGTGGTGGCCCACCAGTCCTAACGGGACAGGACAGAGAGACAGAGCAGCCCTGCACTGTTTTCCCTCCACCACAGCCATCC
TGTCCCTCATTGGCTCTGTGCTTTCCACTATACACAGTCACCGTCCCAATGAGAAACAAGAAGGAGCACCCTCCACATGGACTCCCACCT
GCAAGTGGACAGCGACATTCAGTCCTGCACTGCTCACCTGGGTTTACTGATGACTCCTGGCTGCCCCACCATCCTCTCTGATCTGTGAGA
AACAGCTAAGCTGCTGTGACTTCCCTTTAGGACAATGTTGTGTAAATCTTTGAAGGACACACCGAAGACCTTTATACTGTGATCTTTTAC
CCCTTTCACTCTTGGCTTTCTTATGTTGCTTTCATGAATGGAATGGAAAAAAGATGACTCAGTTAAGGCACCAGCCATATGTGTATTCTT
GATGGTCTATATCGGGGTGTGAGCAGATGTTTGCGTATTTCTTGTGGGTGTGACTGGATATTAGACATCCGGACAAGTGACTGAACTAAT
GATCTGCTGAATAATGAAGGAGGAATAGACACCCCAGTCCCCACCCTACGTGCACCCGCTCTGCAAGTTCCCATGTGATCTGTAGACCAG
GGGAAATTACACTGCGGTCAAGGGCAGAGCCTGCACATGACAGCAAGTGAGCATTTGATAGATGCTCAGATGCTAGTGCAGAGAGCCTGC
TGGGAGACGAAGAGACAGCAGGCAGAGCTCCAGATGGGCAAGGAAGAGGCTTGGTTCTAGCCTGGCTCTGCCCCTCACTGCAGTGGATCC
AGTGGGGCAGAGGACAGAGGGTCACAACCAATGAGGGATGTCTGCCAAGGATGGGGGTGCAGAGGCCACAGGAGTCAGCTTGCCACTCGC
CCATTGGTTACATAGATGATCTCTCAGACAGGCTGGGACTCAGAGTTATTTCCTAGTATCGGTGTGCCCCATCCAGTTTTAAGTGGAGCC
CTCCAAGACTCTCCAGAGCTGCCTTTGAACATCCTAACAGTAATCACATCTCACCCTCCCTGAGGTTCACTTTAGACAGGACCCAATGGC
TGCACTGCCTTTGTCAGAGGGGGTGCTGAGAGGAGTGGCTTCTTTTAGAATCAAACAGTAGAGACAAGAGTCAAGCCTTGTGTCTTCAAG
CATTGACCAAGTTAAGTGTTTCCTTCCCTCTCTCAATAAGACACTTCCAGGAGCTTTCCAATCTCTCACTTAAAACTAAGGTTTGAATCT
CAAAGTGTTGCTGGGAGGCTGATACTCCTGCAACTTCAGGAGACCTGTGAGCACACATTAGCAGCTGTTTCTCTGACTCCTTGTGGCATC
AGATAAAAACGTGGGAGTTTTTCCATATAATTCCCAGCCTTACTTATAAATTCTATTCTTTGAAAAAATTATTCAGGCTAGGTAAGGTGG
CTCATACCTATAATCCCAGCCCTTTGAGAGGCCAAGGTGGGAGAATTGCTTGAGGCCAGGAGTTTGAGACCTCCTGGGCAACATAGTGAG
ATCCCATCTCTACAAAAAACAAAACAAAAAAATTACCCAAGCATGATGGTATATGCCTGTAGTCGTACCTACTTACTTAGGAGGCTGAGG
CAGGAGGATCACTTGAGCCCTGGAGGTTGGGGCTGCAGTGAGCCATGATCGCATCACTATACTCGAGCCTGGGCAACAGAGTGAGACCTT

>33394_33394_1_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000277865_MLPH_chr2_238427182_ENST00000264605_length(amino acids)=667AA_BP=215
MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLR
TRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG
GAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIAGPELISEERSGDSDQTDEDGEPGSEAQAQAQPFGSKKKRLLSVHDFDFEGDSDD
STQPQGHSLHLSSVPEARDSPQSLTDESCSEKAAPHKAEGLEEADTGASGCHSHPEEQPTSISPSRHGALAELCPPGGSHRMALGTAAAL
GSNVIRNEQLPLQYLADVDTSDEESIRAHVMASHHSKRRGRASSESQIFELNKHISAVECLLTYLENTVVPPLAKGLGAGVRTEADVEEE
ALRRKLEELTSNVSDQETSSEEEEAKDEKAEPNRDKSVGPLPQADPEVGTAAHQTNRQEKSPQDPGDPVQYNRTTDEELSELEDRVAVTA
SEVQQAESEVSDIESRIAALRAAGLTVKPSGKPRRKSNLPIFLPRVAGKLGKRPEDPNADPSSEAKAMAVPYLLRRKFSNSLKSQGKDDD

--------------------------------------------------------------
>33394_33394_2_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000277865_MLPH_chr2_238427182_ENST00000410032_length(transcript)=2076nt_BP=743nt
GGGCAACCCGCGCGGGACCCTTCCTCCCTAGTCGCGGGGAGTCTGAGAAAGCGCGCCTGTTTCGCGACCATCACGCACCTCCCCTCCGCT
TGTGGCCATGTACCGCTACCTGGGCGAAGCGCTGTTGCTGTCCCGGGCCGGGCCCGCTGCCCTGGGCTCGGCGTCCGCCGACTCGGCCGC
GTTGCTGGGCTGGGCCCGGGGACAGCCCGCCGCCGCCCCGCAGCCGGGGCTGGCATTGGCCGCCCGGCGCCACTACAGCGAGGCGGTGGC
CGACCGCGAGGACGACCCCAACTTCTTCAAGATGGTGGAGGGCTTCTTCGATCGCGGCGCCAGCATCGTGGAGGACAAGCTGGTGGAGGA
CCTGAGGACCCGGGAGAGCGAGGAGCAGAAGCGGAACCGGGTGCGCGGCATCCTGCGGATCATCAAGCCCTGCAACCATGTGCTGAGTCT
CTCCTTCCCCATCCGGCGCGACGACGGCTCCTGGGAGGTCATCGAAGGCTACCGGGCCCAGCACAGCCAGCACCGCACGCCCTGCAAGGG
AGGTATCCGTTACAGCACTGATGTGAGTGTAGATGAAGTAAAAGCTTTGGCTTCTCTGATGACATACAAGTGTGCAGTGGTTGATGTGCC
GTTTGGGGGTGCTAAAGCTGGTGTTAAGATCAATCCCAAGAACTATACTGATAATGAATTGGAAAAGATCACAAGGAGGTTCACCATGGA
GCTAGCAAAAAAGGGCTTTATTGCTGGGCCTGAACTGATATCTGAAGAGAGAAGTGGAGACAGCGACCAGACAGATGAGGATGGAGAACC
TGGCTCAGAGGCCCAGGCCCAGGCCCAGCCCTTTGGCAGCAAAAAAAAGCGCCTCCTCTCCGTCCACGACTTCGACTTCGAGGGAGACTC
AGATGACTCCACTCAGCCTCAAGGTCACTCCCTGCACCTGTCCTCAGTCCCTGAGGCCAGGGACAGCCCACAGGGTCTAGGTGCTGGAGT
GCGCACGGAGGCCGATGTAGAGGAGGAGGCCCTGAGGAGGAAGCTGGAGGAGCTGACCAGCAACGTCAGTGACCAGGAGACCTCGTCCGA
GGAGGAGGAAGCCAAGGACGAAAAGGCAGAGCCCAACAGGGACAAATCAGTTGGGCCTCTCCCCCAGGCGGACCCGGAGGTGGGCACGGC
TGCCCATCAAACCAACAGACAGGAAAAAAGCCCCCAGGACCCTGGGGACCCCGTCCAGTACAACAGGACCACAGATGAGGAGCTGTCAGA
GCTGGAGGACAGAGTGGCAGTGACGGCCTCAGAAGTCCAGCAGGCAGAGAGCGAGGTTTCAGACATTGAATCCAGGATTGCAGCCCTGAG
GGCCGCAGGGCTCACGGTGAAGCCCTCGGGAAAGCCCCGGAGGAAGTCAAACCTCCCGATATTTCTCCCTCGAGTGGCTGGGAAACTTGG
CAAGAGACCAGAGGACCCAAATGCAGACCCTTCAAGTGAGGCCAAGGCAATGGCTGTGCCCTATCTTCTGAGAAGAAAGTTCAGTAATTC
CCTGAAAAGTCAAGGTAAAGATGATGATTCTTTTGATCGGAAATCAGTGTACCGAGGCTCGCTGACACAGAGAAACCCCAACGCGAGGAA
AGGAATGGCCAGCCACACCTTCGCGAAACCTGTGGTGGCCCACCAGTCCTAACGGGACAGGACAGAGAGACAGAGCAGCCCTGCACTGTT
TTCCCTCCACCACAGCCATCCTGTCCCTCATTGGCTCTGTGCTTTCCACTATACACAGTCACCGTCCCAATGAGAAACAAGAAGGAGCAC
CCTCCACATGGACTCCCACCTGCAAGTGGACAGCGACATTCAGTCCTGCACTGCTCACCTGGGTTTACTGATGACTCCTGGCTGCCCCAC
CATCCTCTCTGATCTGTGAGAAACAGCTAAGCTGCTGTGACTTCCCTTTAGGACAATGTTGTGTAAATCTTTGAAGGACACACCGAAGAC
CTTTATACTGTGATCTTTTACCCCTTTCACTCTTGGCTTTCTTATGTTGCTTTCATGAATGGAATGGAAAAAAGATGACTCAGTTAAGGC

>33394_33394_2_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000277865_MLPH_chr2_238427182_ENST00000410032_length(amino acids)=524AA_BP=215
MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLR
TRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG
GAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIAGPELISEERSGDSDQTDEDGEPGSEAQAQAQPFGSKKKRLLSVHDFDFEGDSDD
STQPQGHSLHLSSVPEARDSPQGLGAGVRTEADVEEEALRRKLEELTSNVSDQETSSEEEEAKDEKAEPNRDKSVGPLPQADPEVGTAAH
QTNRQEKSPQDPGDPVQYNRTTDEELSELEDRVAVTASEVQQAESEVSDIESRIAALRAAGLTVKPSGKPRRKSNLPIFLPRVAGKLGKR

--------------------------------------------------------------
>33394_33394_3_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000277865_MLPH_chr2_238427182_ENST00000445024_length(transcript)=2360nt_BP=743nt
GGGCAACCCGCGCGGGACCCTTCCTCCCTAGTCGCGGGGAGTCTGAGAAAGCGCGCCTGTTTCGCGACCATCACGCACCTCCCCTCCGCT
TGTGGCCATGTACCGCTACCTGGGCGAAGCGCTGTTGCTGTCCCGGGCCGGGCCCGCTGCCCTGGGCTCGGCGTCCGCCGACTCGGCCGC
GTTGCTGGGCTGGGCCCGGGGACAGCCCGCCGCCGCCCCGCAGCCGGGGCTGGCATTGGCCGCCCGGCGCCACTACAGCGAGGCGGTGGC
CGACCGCGAGGACGACCCCAACTTCTTCAAGATGGTGGAGGGCTTCTTCGATCGCGGCGCCAGCATCGTGGAGGACAAGCTGGTGGAGGA
CCTGAGGACCCGGGAGAGCGAGGAGCAGAAGCGGAACCGGGTGCGCGGCATCCTGCGGATCATCAAGCCCTGCAACCATGTGCTGAGTCT
CTCCTTCCCCATCCGGCGCGACGACGGCTCCTGGGAGGTCATCGAAGGCTACCGGGCCCAGCACAGCCAGCACCGCACGCCCTGCAAGGG
AGGTATCCGTTACAGCACTGATGTGAGTGTAGATGAAGTAAAAGCTTTGGCTTCTCTGATGACATACAAGTGTGCAGTGGTTGATGTGCC
GTTTGGGGGTGCTAAAGCTGGTGTTAAGATCAATCCCAAGAACTATACTGATAATGAATTGGAAAAGATCACAAGGAGGTTCACCATGGA
GCTAGCAAAAAAGGGCTTTATTGCTGGGCCTGAACTGATATCTGAAGAGAGAAGTGGAGACAGCGACCAGACAGATGAGGATGGAGAACC
TGGCTCAGAGGCCCAGGCCCAGGCCCAGCCCTTTGGCAGCAAAAAAAAGCGCCTCCTCTCCGTCCACGACTTCGACTTCGAGGGAGACTC
AGATGACTCCACTCAGCCTCAAGGTCACTCCCTGCACCTGTCCTCAGTCCCTGAGGCCAGGGACAGCCCACAGTCCCTCACAGATGAGTC
CTGCTCAGAGAAGGCAGCCCCTCACAAGGCTGAGGGCCTGGAGGAGGCTGATACTGGGGCCTCTGGGTGCCACTCCCATCCGGAAGAGCA
GCCGACCAGCATCTCACCTTCCAGACACGGCGCCCTGGCTGAGCTCTGCCCGCCTGGAGGCTCCCACAGGATGGCCCTGGGGACTGCTGC
TGCACTCGGGTCGAATGTCATCAGGAATGAGCAGCTGCCCCTGCAGTACTTGGCCGATGTGGACACCTCTGATGAGGAAAGCATCCGGGC
TCACGTGATGGCCTCCCACCATTCCAAGCGGAGAGGCCGGGCGTCTTCTGAGAGTCAGATCTTTGAGCTGAATAAGCATATTTCAGCTGT
GGAATGCCTGCTGACCTACCTGGAGAACACAGTTGTGCCTCCCTTGGCCAAGGGTCTAGGTGCTGGAGTGCGCACGGAGGCCGATGTAGA
GGAGGAGGCCCTGAGGAGGAAGCTGGAGGAGCTGACCAGCAACGTCAGTGACCAGGAGACCTCGTCCGAGGAGGAGGAAGCCAAGGACGA
AAAGGCAGAGCCCAACAGGGACAAATCAGTTGGGCCTCTCCCCCAGGCGGACCCGGAGGTGGGCACGGCTGCCCATCAAACCAACAGACA
GGAAAAAAGCCCCCAGGACCCTGGGGACCCCGTCCAGTACAACAGGACCACAGATGAGGAGCTGTCAGAGCTGGAGGACAGAGTGGCAGT
GACGGCCTCAGAAGTCCAGCAGGCAGAGAGCGAGGTTTCAGACATTGAATCCAGGATTGCAGCCCTGAGGGCCGCAGGGCTCACGGTGAA
GCCCTCGGGAAAGCCCCGGAGGAAGTCAAACCTCCCGGCTCTTTATGAGGGGACTCTGAGCCTCTGCTCTGAGGATCTGAAACACACACA
CCCTGACAGTGTAAAATCCAAAAGGAGCCGCCTGAATCATGTTGCCTCATGTGGAAATCCTTAGTCCGCCGCCACGTGAAGATGGATGTG
ACTAGAACGGAGGGCGCGGGAGGCTCACATCAGAGGAGCTGCTCACATATTTCTCCCTCGAGTGGCTGGGAAACTTGGCAAGAGACCAGA
GGACCCAAATGCAGACCCTTCAAGTGAGGCCAAGGCAATGGCTGTGCCCTATCTTCTGAGAAGAAAGTTCAGTAATTCCCTGAAAAGTCA
AGGTAAAGATGATGATTCTTTTGATCGGAAATCAGTGTACCGAGGCTCGCTGACACAGAGAAACCCCAACGCGAGGAAAGGAATGGCCAG
CCACACCTTCGCGAAACCTGTGGTGGCCCACCAGTCCTAACGGGACAGGACAGAGAGACAGAGCAGCCCTGCACTGTTTTCCCTCCACCA

>33394_33394_3_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000277865_MLPH_chr2_238427182_ENST00000445024_length(amino acids)=618AA_BP=215
MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLR
TRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG
GAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIAGPELISEERSGDSDQTDEDGEPGSEAQAQAQPFGSKKKRLLSVHDFDFEGDSDD
STQPQGHSLHLSSVPEARDSPQSLTDESCSEKAAPHKAEGLEEADTGASGCHSHPEEQPTSISPSRHGALAELCPPGGSHRMALGTAAAL
GSNVIRNEQLPLQYLADVDTSDEESIRAHVMASHHSKRRGRASSESQIFELNKHISAVECLLTYLENTVVPPLAKGLGAGVRTEADVEEE
ALRRKLEELTSNVSDQETSSEEEEAKDEKAEPNRDKSVGPLPQADPEVGTAAHQTNRQEKSPQDPGDPVQYNRTTDEELSELEDRVAVTA

--------------------------------------------------------------
>33394_33394_4_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000537649_MLPH_chr2_238427182_ENST00000264605_length(transcript)=3776nt_BP=692nt
ATGCAGAGTAGACGCTGCACCGGTCTCCTTTTGGTCCCGGTGTCTGTGTCACACACGGCGGGTCCTGCCGAAATGCACTTCTAGGAAAGG
GAATGACCTGCCCGTGTGATAATGCCTCGTCAGTGTTCTTGGGCTTTTATGCCCAGCTCTCTCCTGTTTTTATAAGTCGCAGCTCCGCAA
ACTCACTGAAGCAACTCGTTTACCATAGTTTTTACTACATGTACCTGAGGCCGTTAGATTTGTCTGTGTTAAGGATTTGAAAGGAGGCAG
AAATTAATACAGATTCAAGTGTTCACTATCAAGTCGGAATTGTTAATATGTGAAATACTACTGTTAAAGGCAGGAAAGGCTTTATTAAGG
ACAAGAAGACAAACTAGGAGAAGGAGCTACTCAAGACCTTCCGATTATCTTTACAAAAAGGCAACTACACCTAGAAGATTCTGCAGCCAC
ACACATTCTGCCTTCACTTGAGGTCAACTGCCTTCACCAAGGTATCCGTTACAGCACTGATGTGAGTGTAGATGAAGTAAAAGCTTTGGC
TTCTCTGATGACATACAAGTGTGCAGTGGTTGATGTGCCGTTTGGGGGTGCTAAAGCTGGTGTTAAGATCAATCCCAAGAACTATACTGA
TAATGAATTGGAAAAGATCACAAGGAGGTTCACCATGGAGCTAGCAAAAAAGGGCTTTATTGCTGGGCCTGAACTGATATCTGAAGAGAG
AAGTGGAGACAGCGACCAGACAGATGAGGATGGAGAACCTGGCTCAGAGGCCCAGGCCCAGGCCCAGCCCTTTGGCAGCAAAAAAAAGCG
CCTCCTCTCCGTCCACGACTTCGACTTCGAGGGAGACTCAGATGACTCCACTCAGCCTCAAGGTCACTCCCTGCACCTGTCCTCAGTCCC
TGAGGCCAGGGACAGCCCACAGTCCCTCACAGATGAGTCCTGCTCAGAGAAGGCAGCCCCTCACAAGGCTGAGGGCCTGGAGGAGGCTGA
TACTGGGGCCTCTGGGTGCCACTCCCATCCGGAAGAGCAGCCGACCAGCATCTCACCTTCCAGACACGGCGCCCTGGCTGAGCTCTGCCC
GCCTGGAGGCTCCCACAGGATGGCCCTGGGGACTGCTGCTGCACTCGGGTCGAATGTCATCAGGAATGAGCAGCTGCCCCTGCAGTACTT
GGCCGATGTGGACACCTCTGATGAGGAAAGCATCCGGGCTCACGTGATGGCCTCCCACCATTCCAAGCGGAGAGGCCGGGCGTCTTCTGA
GAGTCAGATCTTTGAGCTGAATAAGCATATTTCAGCTGTGGAATGCCTGCTGACCTACCTGGAGAACACAGTTGTGCCTCCCTTGGCCAA
GGGTCTAGGTGCTGGAGTGCGCACGGAGGCCGATGTAGAGGAGGAGGCCCTGAGGAGGAAGCTGGAGGAGCTGACCAGCAACGTCAGTGA
CCAGGAGACCTCGTCCGAGGAGGAGGAAGCCAAGGACGAAAAGGCAGAGCCCAACAGGGACAAATCAGTTGGGCCTCTCCCCCAGGCGGA
CCCGGAGGTGGGCACGGCTGCCCATCAAACCAACAGACAGGAAAAAAGCCCCCAGGACCCTGGGGACCCCGTCCAGTACAACAGGACCAC
AGATGAGGAGCTGTCAGAGCTGGAGGACAGAGTGGCAGTGACGGCCTCAGAAGTCCAGCAGGCAGAGAGCGAGGTTTCAGACATTGAATC
CAGGATTGCAGCCCTGAGGGCCGCAGGGCTCACGGTGAAGCCCTCGGGAAAGCCCCGGAGGAAGTCAAACCTCCCGATATTTCTCCCTCG
AGTGGCTGGGAAACTTGGCAAGAGACCAGAGGACCCAAATGCAGACCCTTCAAGTGAGGCCAAGGCAATGGCTGTGCCCTATCTTCTGAG
AAGAAAGTTCAGTAATTCCCTGAAAAGTCAAGGTAAAGATGATGATTCTTTTGATCGGAAATCAGTGTACCGAGGCTCGCTGACACAGAG
AAACCCCAACGCGAGGAAAGGAATGGCCAGCCACACCTTCGCGAAACCTGTGGTGGCCCACCAGTCCTAACGGGACAGGACAGAGAGACA
GAGCAGCCCTGCACTGTTTTCCCTCCACCACAGCCATCCTGTCCCTCATTGGCTCTGTGCTTTCCACTATACACAGTCACCGTCCCAATG
AGAAACAAGAAGGAGCACCCTCCACATGGACTCCCACCTGCAAGTGGACAGCGACATTCAGTCCTGCACTGCTCACCTGGGTTTACTGAT
GACTCCTGGCTGCCCCACCATCCTCTCTGATCTGTGAGAAACAGCTAAGCTGCTGTGACTTCCCTTTAGGACAATGTTGTGTAAATCTTT
GAAGGACACACCGAAGACCTTTATACTGTGATCTTTTACCCCTTTCACTCTTGGCTTTCTTATGTTGCTTTCATGAATGGAATGGAAAAA
AGATGACTCAGTTAAGGCACCAGCCATATGTGTATTCTTGATGGTCTATATCGGGGTGTGAGCAGATGTTTGCGTATTTCTTGTGGGTGT
GACTGGATATTAGACATCCGGACAAGTGACTGAACTAATGATCTGCTGAATAATGAAGGAGGAATAGACACCCCAGTCCCCACCCTACGT
GCACCCGCTCTGCAAGTTCCCATGTGATCTGTAGACCAGGGGAAATTACACTGCGGTCAAGGGCAGAGCCTGCACATGACAGCAAGTGAG
CATTTGATAGATGCTCAGATGCTAGTGCAGAGAGCCTGCTGGGAGACGAAGAGACAGCAGGCAGAGCTCCAGATGGGCAAGGAAGAGGCT
TGGTTCTAGCCTGGCTCTGCCCCTCACTGCAGTGGATCCAGTGGGGCAGAGGACAGAGGGTCACAACCAATGAGGGATGTCTGCCAAGGA
TGGGGGTGCAGAGGCCACAGGAGTCAGCTTGCCACTCGCCCATTGGTTACATAGATGATCTCTCAGACAGGCTGGGACTCAGAGTTATTT
CCTAGTATCGGTGTGCCCCATCCAGTTTTAAGTGGAGCCCTCCAAGACTCTCCAGAGCTGCCTTTGAACATCCTAACAGTAATCACATCT
CACCCTCCCTGAGGTTCACTTTAGACAGGACCCAATGGCTGCACTGCCTTTGTCAGAGGGGGTGCTGAGAGGAGTGGCTTCTTTTAGAAT
CAAACAGTAGAGACAAGAGTCAAGCCTTGTGTCTTCAAGCATTGACCAAGTTAAGTGTTTCCTTCCCTCTCTCAATAAGACACTTCCAGG
AGCTTTCCAATCTCTCACTTAAAACTAAGGTTTGAATCTCAAAGTGTTGCTGGGAGGCTGATACTCCTGCAACTTCAGGAGACCTGTGAG
CACACATTAGCAGCTGTTTCTCTGACTCCTTGTGGCATCAGATAAAAACGTGGGAGTTTTTCCATATAATTCCCAGCCTTACTTATAAAT
TCTATTCTTTGAAAAAATTATTCAGGCTAGGTAAGGTGGCTCATACCTATAATCCCAGCCCTTTGAGAGGCCAAGGTGGGAGAATTGCTT
GAGGCCAGGAGTTTGAGACCTCCTGGGCAACATAGTGAGATCCCATCTCTACAAAAAACAAAACAAAAAAATTACCCAAGCATGATGGTA
TATGCCTGTAGTCGTACCTACTTACTTAGGAGGCTGAGGCAGGAGGATCACTTGAGCCCTGGAGGTTGGGGCTGCAGTGAGCCATGATCG

>33394_33394_4_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000537649_MLPH_chr2_238427182_ENST00000264605_length(amino acids)=530AA_BP=78
MPSLEVNCLHQGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIAGPELISEERSG
DSDQTDEDGEPGSEAQAQAQPFGSKKKRLLSVHDFDFEGDSDDSTQPQGHSLHLSSVPEARDSPQSLTDESCSEKAAPHKAEGLEEADTG
ASGCHSHPEEQPTSISPSRHGALAELCPPGGSHRMALGTAAALGSNVIRNEQLPLQYLADVDTSDEESIRAHVMASHHSKRRGRASSESQ
IFELNKHISAVECLLTYLENTVVPPLAKGLGAGVRTEADVEEEALRRKLEELTSNVSDQETSSEEEEAKDEKAEPNRDKSVGPLPQADPE
VGTAAHQTNRQEKSPQDPGDPVQYNRTTDEELSELEDRVAVTASEVQQAESEVSDIESRIAALRAAGLTVKPSGKPRRKSNLPIFLPRVA

--------------------------------------------------------------
>33394_33394_5_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000537649_MLPH_chr2_238427182_ENST00000410032_length(transcript)=2025nt_BP=692nt
ATGCAGAGTAGACGCTGCACCGGTCTCCTTTTGGTCCCGGTGTCTGTGTCACACACGGCGGGTCCTGCCGAAATGCACTTCTAGGAAAGG
GAATGACCTGCCCGTGTGATAATGCCTCGTCAGTGTTCTTGGGCTTTTATGCCCAGCTCTCTCCTGTTTTTATAAGTCGCAGCTCCGCAA
ACTCACTGAAGCAACTCGTTTACCATAGTTTTTACTACATGTACCTGAGGCCGTTAGATTTGTCTGTGTTAAGGATTTGAAAGGAGGCAG
AAATTAATACAGATTCAAGTGTTCACTATCAAGTCGGAATTGTTAATATGTGAAATACTACTGTTAAAGGCAGGAAAGGCTTTATTAAGG
ACAAGAAGACAAACTAGGAGAAGGAGCTACTCAAGACCTTCCGATTATCTTTACAAAAAGGCAACTACACCTAGAAGATTCTGCAGCCAC
ACACATTCTGCCTTCACTTGAGGTCAACTGCCTTCACCAAGGTATCCGTTACAGCACTGATGTGAGTGTAGATGAAGTAAAAGCTTTGGC
TTCTCTGATGACATACAAGTGTGCAGTGGTTGATGTGCCGTTTGGGGGTGCTAAAGCTGGTGTTAAGATCAATCCCAAGAACTATACTGA
TAATGAATTGGAAAAGATCACAAGGAGGTTCACCATGGAGCTAGCAAAAAAGGGCTTTATTGCTGGGCCTGAACTGATATCTGAAGAGAG
AAGTGGAGACAGCGACCAGACAGATGAGGATGGAGAACCTGGCTCAGAGGCCCAGGCCCAGGCCCAGCCCTTTGGCAGCAAAAAAAAGCG
CCTCCTCTCCGTCCACGACTTCGACTTCGAGGGAGACTCAGATGACTCCACTCAGCCTCAAGGTCACTCCCTGCACCTGTCCTCAGTCCC
TGAGGCCAGGGACAGCCCACAGGGTCTAGGTGCTGGAGTGCGCACGGAGGCCGATGTAGAGGAGGAGGCCCTGAGGAGGAAGCTGGAGGA
GCTGACCAGCAACGTCAGTGACCAGGAGACCTCGTCCGAGGAGGAGGAAGCCAAGGACGAAAAGGCAGAGCCCAACAGGGACAAATCAGT
TGGGCCTCTCCCCCAGGCGGACCCGGAGGTGGGCACGGCTGCCCATCAAACCAACAGACAGGAAAAAAGCCCCCAGGACCCTGGGGACCC
CGTCCAGTACAACAGGACCACAGATGAGGAGCTGTCAGAGCTGGAGGACAGAGTGGCAGTGACGGCCTCAGAAGTCCAGCAGGCAGAGAG
CGAGGTTTCAGACATTGAATCCAGGATTGCAGCCCTGAGGGCCGCAGGGCTCACGGTGAAGCCCTCGGGAAAGCCCCGGAGGAAGTCAAA
CCTCCCGATATTTCTCCCTCGAGTGGCTGGGAAACTTGGCAAGAGACCAGAGGACCCAAATGCAGACCCTTCAAGTGAGGCCAAGGCAAT
GGCTGTGCCCTATCTTCTGAGAAGAAAGTTCAGTAATTCCCTGAAAAGTCAAGGTAAAGATGATGATTCTTTTGATCGGAAATCAGTGTA
CCGAGGCTCGCTGACACAGAGAAACCCCAACGCGAGGAAAGGAATGGCCAGCCACACCTTCGCGAAACCTGTGGTGGCCCACCAGTCCTA
ACGGGACAGGACAGAGAGACAGAGCAGCCCTGCACTGTTTTCCCTCCACCACAGCCATCCTGTCCCTCATTGGCTCTGTGCTTTCCACTA
TACACAGTCACCGTCCCAATGAGAAACAAGAAGGAGCACCCTCCACATGGACTCCCACCTGCAAGTGGACAGCGACATTCAGTCCTGCAC
TGCTCACCTGGGTTTACTGATGACTCCTGGCTGCCCCACCATCCTCTCTGATCTGTGAGAAACAGCTAAGCTGCTGTGACTTCCCTTTAG
GACAATGTTGTGTAAATCTTTGAAGGACACACCGAAGACCTTTATACTGTGATCTTTTACCCCTTTCACTCTTGGCTTTCTTATGTTGCT

>33394_33394_5_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000537649_MLPH_chr2_238427182_ENST00000410032_length(amino acids)=387AA_BP=78
MPSLEVNCLHQGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIAGPELISEERSG
DSDQTDEDGEPGSEAQAQAQPFGSKKKRLLSVHDFDFEGDSDDSTQPQGHSLHLSSVPEARDSPQGLGAGVRTEADVEEEALRRKLEELT
SNVSDQETSSEEEEAKDEKAEPNRDKSVGPLPQADPEVGTAAHQTNRQEKSPQDPGDPVQYNRTTDEELSELEDRVAVTASEVQQAESEV
SDIESRIAALRAAGLTVKPSGKPRRKSNLPIFLPRVAGKLGKRPEDPNADPSSEAKAMAVPYLLRRKFSNSLKSQGKDDDSFDRKSVYRG

--------------------------------------------------------------
>33394_33394_6_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000537649_MLPH_chr2_238427182_ENST00000445024_length(transcript)=2309nt_BP=692nt
ATGCAGAGTAGACGCTGCACCGGTCTCCTTTTGGTCCCGGTGTCTGTGTCACACACGGCGGGTCCTGCCGAAATGCACTTCTAGGAAAGG
GAATGACCTGCCCGTGTGATAATGCCTCGTCAGTGTTCTTGGGCTTTTATGCCCAGCTCTCTCCTGTTTTTATAAGTCGCAGCTCCGCAA
ACTCACTGAAGCAACTCGTTTACCATAGTTTTTACTACATGTACCTGAGGCCGTTAGATTTGTCTGTGTTAAGGATTTGAAAGGAGGCAG
AAATTAATACAGATTCAAGTGTTCACTATCAAGTCGGAATTGTTAATATGTGAAATACTACTGTTAAAGGCAGGAAAGGCTTTATTAAGG
ACAAGAAGACAAACTAGGAGAAGGAGCTACTCAAGACCTTCCGATTATCTTTACAAAAAGGCAACTACACCTAGAAGATTCTGCAGCCAC
ACACATTCTGCCTTCACTTGAGGTCAACTGCCTTCACCAAGGTATCCGTTACAGCACTGATGTGAGTGTAGATGAAGTAAAAGCTTTGGC
TTCTCTGATGACATACAAGTGTGCAGTGGTTGATGTGCCGTTTGGGGGTGCTAAAGCTGGTGTTAAGATCAATCCCAAGAACTATACTGA
TAATGAATTGGAAAAGATCACAAGGAGGTTCACCATGGAGCTAGCAAAAAAGGGCTTTATTGCTGGGCCTGAACTGATATCTGAAGAGAG
AAGTGGAGACAGCGACCAGACAGATGAGGATGGAGAACCTGGCTCAGAGGCCCAGGCCCAGGCCCAGCCCTTTGGCAGCAAAAAAAAGCG
CCTCCTCTCCGTCCACGACTTCGACTTCGAGGGAGACTCAGATGACTCCACTCAGCCTCAAGGTCACTCCCTGCACCTGTCCTCAGTCCC
TGAGGCCAGGGACAGCCCACAGTCCCTCACAGATGAGTCCTGCTCAGAGAAGGCAGCCCCTCACAAGGCTGAGGGCCTGGAGGAGGCTGA
TACTGGGGCCTCTGGGTGCCACTCCCATCCGGAAGAGCAGCCGACCAGCATCTCACCTTCCAGACACGGCGCCCTGGCTGAGCTCTGCCC
GCCTGGAGGCTCCCACAGGATGGCCCTGGGGACTGCTGCTGCACTCGGGTCGAATGTCATCAGGAATGAGCAGCTGCCCCTGCAGTACTT
GGCCGATGTGGACACCTCTGATGAGGAAAGCATCCGGGCTCACGTGATGGCCTCCCACCATTCCAAGCGGAGAGGCCGGGCGTCTTCTGA
GAGTCAGATCTTTGAGCTGAATAAGCATATTTCAGCTGTGGAATGCCTGCTGACCTACCTGGAGAACACAGTTGTGCCTCCCTTGGCCAA
GGGTCTAGGTGCTGGAGTGCGCACGGAGGCCGATGTAGAGGAGGAGGCCCTGAGGAGGAAGCTGGAGGAGCTGACCAGCAACGTCAGTGA
CCAGGAGACCTCGTCCGAGGAGGAGGAAGCCAAGGACGAAAAGGCAGAGCCCAACAGGGACAAATCAGTTGGGCCTCTCCCCCAGGCGGA
CCCGGAGGTGGGCACGGCTGCCCATCAAACCAACAGACAGGAAAAAAGCCCCCAGGACCCTGGGGACCCCGTCCAGTACAACAGGACCAC
AGATGAGGAGCTGTCAGAGCTGGAGGACAGAGTGGCAGTGACGGCCTCAGAAGTCCAGCAGGCAGAGAGCGAGGTTTCAGACATTGAATC
CAGGATTGCAGCCCTGAGGGCCGCAGGGCTCACGGTGAAGCCCTCGGGAAAGCCCCGGAGGAAGTCAAACCTCCCGGCTCTTTATGAGGG
GACTCTGAGCCTCTGCTCTGAGGATCTGAAACACACACACCCTGACAGTGTAAAATCCAAAAGGAGCCGCCTGAATCATGTTGCCTCATG
TGGAAATCCTTAGTCCGCCGCCACGTGAAGATGGATGTGACTAGAACGGAGGGCGCGGGAGGCTCACATCAGAGGAGCTGCTCACATATT
TCTCCCTCGAGTGGCTGGGAAACTTGGCAAGAGACCAGAGGACCCAAATGCAGACCCTTCAAGTGAGGCCAAGGCAATGGCTGTGCCCTA
TCTTCTGAGAAGAAAGTTCAGTAATTCCCTGAAAAGTCAAGGTAAAGATGATGATTCTTTTGATCGGAAATCAGTGTACCGAGGCTCGCT
GACACAGAGAAACCCCAACGCGAGGAAAGGAATGGCCAGCCACACCTTCGCGAAACCTGTGGTGGCCCACCAGTCCTAACGGGACAGGAC

>33394_33394_6_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000537649_MLPH_chr2_238427182_ENST00000445024_length(amino acids)=481AA_BP=78
MPSLEVNCLHQGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIAGPELISEERSG
DSDQTDEDGEPGSEAQAQAQPFGSKKKRLLSVHDFDFEGDSDDSTQPQGHSLHLSSVPEARDSPQSLTDESCSEKAAPHKAEGLEEADTG
ASGCHSHPEEQPTSISPSRHGALAELCPPGGSHRMALGTAAALGSNVIRNEQLPLQYLADVDTSDEESIRAHVMASHHSKRRGRASSESQ
IFELNKHISAVECLLTYLENTVVPPLAKGLGAGVRTEADVEEEALRRKLEELTSNVSDQETSSEEEEAKDEKAEPNRDKSVGPLPQADPE
VGTAAHQTNRQEKSPQDPGDPVQYNRTTDEELSELEDRVAVTASEVQQAESEVSDIESRIAALRAAGLTVKPSGKPRRKSNLPALYEGTL

--------------------------------------------------------------
>33394_33394_7_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000544149_MLPH_chr2_238427182_ENST00000264605_length(transcript)=3440nt_BP=356nt
GTATATGCTGATCTTGCATGCAGAGTAGACGCTGCACCGGTCTCCTTTTGGTCCCGGTGTCTGTGTCACACACGGCGGGTCCTGCCGAAA
TGCACTTCTAGGAAAGGGAATGACCTGCCCGTGTGATAATGCCTCGTCAGTGTTCTTGGGCTTTTGTATCCGTTACAGCACTGATGTGAG
TGTAGATGAAGTAAAAGCTTTGGCTTCTCTGATGACATACAAGTGTGCAGTGGTTGATGTGCCGTTTGGGGGTGCTAAAGCTGGTGTTAA
GATCAATCCCAAGAACTATACTGATAATGAATTGGAAAAGATCACAAGGAGGTTCACCATGGAGCTAGCAAAAAAGGGCTTTATTGCTGG
GCCTGAACTGATATCTGAAGAGAGAAGTGGAGACAGCGACCAGACAGATGAGGATGGAGAACCTGGCTCAGAGGCCCAGGCCCAGGCCCA
GCCCTTTGGCAGCAAAAAAAAGCGCCTCCTCTCCGTCCACGACTTCGACTTCGAGGGAGACTCAGATGACTCCACTCAGCCTCAAGGTCA
CTCCCTGCACCTGTCCTCAGTCCCTGAGGCCAGGGACAGCCCACAGTCCCTCACAGATGAGTCCTGCTCAGAGAAGGCAGCCCCTCACAA
GGCTGAGGGCCTGGAGGAGGCTGATACTGGGGCCTCTGGGTGCCACTCCCATCCGGAAGAGCAGCCGACCAGCATCTCACCTTCCAGACA
CGGCGCCCTGGCTGAGCTCTGCCCGCCTGGAGGCTCCCACAGGATGGCCCTGGGGACTGCTGCTGCACTCGGGTCGAATGTCATCAGGAA
TGAGCAGCTGCCCCTGCAGTACTTGGCCGATGTGGACACCTCTGATGAGGAAAGCATCCGGGCTCACGTGATGGCCTCCCACCATTCCAA
GCGGAGAGGCCGGGCGTCTTCTGAGAGTCAGATCTTTGAGCTGAATAAGCATATTTCAGCTGTGGAATGCCTGCTGACCTACCTGGAGAA
CACAGTTGTGCCTCCCTTGGCCAAGGGTCTAGGTGCTGGAGTGCGCACGGAGGCCGATGTAGAGGAGGAGGCCCTGAGGAGGAAGCTGGA
GGAGCTGACCAGCAACGTCAGTGACCAGGAGACCTCGTCCGAGGAGGAGGAAGCCAAGGACGAAAAGGCAGAGCCCAACAGGGACAAATC
AGTTGGGCCTCTCCCCCAGGCGGACCCGGAGGTGGGCACGGCTGCCCATCAAACCAACAGACAGGAAAAAAGCCCCCAGGACCCTGGGGA
CCCCGTCCAGTACAACAGGACCACAGATGAGGAGCTGTCAGAGCTGGAGGACAGAGTGGCAGTGACGGCCTCAGAAGTCCAGCAGGCAGA
GAGCGAGGTTTCAGACATTGAATCCAGGATTGCAGCCCTGAGGGCCGCAGGGCTCACGGTGAAGCCCTCGGGAAAGCCCCGGAGGAAGTC
AAACCTCCCGATATTTCTCCCTCGAGTGGCTGGGAAACTTGGCAAGAGACCAGAGGACCCAAATGCAGACCCTTCAAGTGAGGCCAAGGC
AATGGCTGTGCCCTATCTTCTGAGAAGAAAGTTCAGTAATTCCCTGAAAAGTCAAGGTAAAGATGATGATTCTTTTGATCGGAAATCAGT
GTACCGAGGCTCGCTGACACAGAGAAACCCCAACGCGAGGAAAGGAATGGCCAGCCACACCTTCGCGAAACCTGTGGTGGCCCACCAGTC
CTAACGGGACAGGACAGAGAGACAGAGCAGCCCTGCACTGTTTTCCCTCCACCACAGCCATCCTGTCCCTCATTGGCTCTGTGCTTTCCA
CTATACACAGTCACCGTCCCAATGAGAAACAAGAAGGAGCACCCTCCACATGGACTCCCACCTGCAAGTGGACAGCGACATTCAGTCCTG
CACTGCTCACCTGGGTTTACTGATGACTCCTGGCTGCCCCACCATCCTCTCTGATCTGTGAGAAACAGCTAAGCTGCTGTGACTTCCCTT
TAGGACAATGTTGTGTAAATCTTTGAAGGACACACCGAAGACCTTTATACTGTGATCTTTTACCCCTTTCACTCTTGGCTTTCTTATGTT
GCTTTCATGAATGGAATGGAAAAAAGATGACTCAGTTAAGGCACCAGCCATATGTGTATTCTTGATGGTCTATATCGGGGTGTGAGCAGA
TGTTTGCGTATTTCTTGTGGGTGTGACTGGATATTAGACATCCGGACAAGTGACTGAACTAATGATCTGCTGAATAATGAAGGAGGAATA
GACACCCCAGTCCCCACCCTACGTGCACCCGCTCTGCAAGTTCCCATGTGATCTGTAGACCAGGGGAAATTACACTGCGGTCAAGGGCAG
AGCCTGCACATGACAGCAAGTGAGCATTTGATAGATGCTCAGATGCTAGTGCAGAGAGCCTGCTGGGAGACGAAGAGACAGCAGGCAGAG
CTCCAGATGGGCAAGGAAGAGGCTTGGTTCTAGCCTGGCTCTGCCCCTCACTGCAGTGGATCCAGTGGGGCAGAGGACAGAGGGTCACAA
CCAATGAGGGATGTCTGCCAAGGATGGGGGTGCAGAGGCCACAGGAGTCAGCTTGCCACTCGCCCATTGGTTACATAGATGATCTCTCAG
ACAGGCTGGGACTCAGAGTTATTTCCTAGTATCGGTGTGCCCCATCCAGTTTTAAGTGGAGCCCTCCAAGACTCTCCAGAGCTGCCTTTG
AACATCCTAACAGTAATCACATCTCACCCTCCCTGAGGTTCACTTTAGACAGGACCCAATGGCTGCACTGCCTTTGTCAGAGGGGGTGCT
GAGAGGAGTGGCTTCTTTTAGAATCAAACAGTAGAGACAAGAGTCAAGCCTTGTGTCTTCAAGCATTGACCAAGTTAAGTGTTTCCTTCC
CTCTCTCAATAAGACACTTCCAGGAGCTTTCCAATCTCTCACTTAAAACTAAGGTTTGAATCTCAAAGTGTTGCTGGGAGGCTGATACTC
CTGCAACTTCAGGAGACCTGTGAGCACACATTAGCAGCTGTTTCTCTGACTCCTTGTGGCATCAGATAAAAACGTGGGAGTTTTTCCATA
TAATTCCCAGCCTTACTTATAAATTCTATTCTTTGAAAAAATTATTCAGGCTAGGTAAGGTGGCTCATACCTATAATCCCAGCCCTTTGA
GAGGCCAAGGTGGGAGAATTGCTTGAGGCCAGGAGTTTGAGACCTCCTGGGCAACATAGTGAGATCCCATCTCTACAAAAAACAAAACAA
AAAAATTACCCAAGCATGATGGTATATGCCTGTAGTCGTACCTACTTACTTAGGAGGCTGAGGCAGGAGGATCACTTGAGCCCTGGAGGT
TGGGGCTGCAGTGAGCCATGATCGCATCACTATACTCGAGCCTGGGCAACAGAGTGAGACCTTGTCTCTTAAAAAAATTAATAATAAATA

>33394_33394_7_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000544149_MLPH_chr2_238427182_ENST00000264605_length(amino acids)=560AA_BP=108
MHRSPFGPGVCVTHGGSCRNALLGKGMTCPCDNASSVFLGFCIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNE
LEKITRRFTMELAKKGFIAGPELISEERSGDSDQTDEDGEPGSEAQAQAQPFGSKKKRLLSVHDFDFEGDSDDSTQPQGHSLHLSSVPEA
RDSPQSLTDESCSEKAAPHKAEGLEEADTGASGCHSHPEEQPTSISPSRHGALAELCPPGGSHRMALGTAAALGSNVIRNEQLPLQYLAD
VDTSDEESIRAHVMASHHSKRRGRASSESQIFELNKHISAVECLLTYLENTVVPPLAKGLGAGVRTEADVEEEALRRKLEELTSNVSDQE
TSSEEEEAKDEKAEPNRDKSVGPLPQADPEVGTAAHQTNRQEKSPQDPGDPVQYNRTTDEELSELEDRVAVTASEVQQAESEVSDIESRI
AALRAAGLTVKPSGKPRRKSNLPIFLPRVAGKLGKRPEDPNADPSSEAKAMAVPYLLRRKFSNSLKSQGKDDDSFDRKSVYRGSLTQRNP

--------------------------------------------------------------
>33394_33394_8_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000544149_MLPH_chr2_238427182_ENST00000410032_length(transcript)=1689nt_BP=356nt
GTATATGCTGATCTTGCATGCAGAGTAGACGCTGCACCGGTCTCCTTTTGGTCCCGGTGTCTGTGTCACACACGGCGGGTCCTGCCGAAA
TGCACTTCTAGGAAAGGGAATGACCTGCCCGTGTGATAATGCCTCGTCAGTGTTCTTGGGCTTTTGTATCCGTTACAGCACTGATGTGAG
TGTAGATGAAGTAAAAGCTTTGGCTTCTCTGATGACATACAAGTGTGCAGTGGTTGATGTGCCGTTTGGGGGTGCTAAAGCTGGTGTTAA
GATCAATCCCAAGAACTATACTGATAATGAATTGGAAAAGATCACAAGGAGGTTCACCATGGAGCTAGCAAAAAAGGGCTTTATTGCTGG
GCCTGAACTGATATCTGAAGAGAGAAGTGGAGACAGCGACCAGACAGATGAGGATGGAGAACCTGGCTCAGAGGCCCAGGCCCAGGCCCA
GCCCTTTGGCAGCAAAAAAAAGCGCCTCCTCTCCGTCCACGACTTCGACTTCGAGGGAGACTCAGATGACTCCACTCAGCCTCAAGGTCA
CTCCCTGCACCTGTCCTCAGTCCCTGAGGCCAGGGACAGCCCACAGGGTCTAGGTGCTGGAGTGCGCACGGAGGCCGATGTAGAGGAGGA
GGCCCTGAGGAGGAAGCTGGAGGAGCTGACCAGCAACGTCAGTGACCAGGAGACCTCGTCCGAGGAGGAGGAAGCCAAGGACGAAAAGGC
AGAGCCCAACAGGGACAAATCAGTTGGGCCTCTCCCCCAGGCGGACCCGGAGGTGGGCACGGCTGCCCATCAAACCAACAGACAGGAAAA
AAGCCCCCAGGACCCTGGGGACCCCGTCCAGTACAACAGGACCACAGATGAGGAGCTGTCAGAGCTGGAGGACAGAGTGGCAGTGACGGC
CTCAGAAGTCCAGCAGGCAGAGAGCGAGGTTTCAGACATTGAATCCAGGATTGCAGCCCTGAGGGCCGCAGGGCTCACGGTGAAGCCCTC
GGGAAAGCCCCGGAGGAAGTCAAACCTCCCGATATTTCTCCCTCGAGTGGCTGGGAAACTTGGCAAGAGACCAGAGGACCCAAATGCAGA
CCCTTCAAGTGAGGCCAAGGCAATGGCTGTGCCCTATCTTCTGAGAAGAAAGTTCAGTAATTCCCTGAAAAGTCAAGGTAAAGATGATGA
TTCTTTTGATCGGAAATCAGTGTACCGAGGCTCGCTGACACAGAGAAACCCCAACGCGAGGAAAGGAATGGCCAGCCACACCTTCGCGAA
ACCTGTGGTGGCCCACCAGTCCTAACGGGACAGGACAGAGAGACAGAGCAGCCCTGCACTGTTTTCCCTCCACCACAGCCATCCTGTCCC
TCATTGGCTCTGTGCTTTCCACTATACACAGTCACCGTCCCAATGAGAAACAAGAAGGAGCACCCTCCACATGGACTCCCACCTGCAAGT
GGACAGCGACATTCAGTCCTGCACTGCTCACCTGGGTTTACTGATGACTCCTGGCTGCCCCACCATCCTCTCTGATCTGTGAGAAACAGC
TAAGCTGCTGTGACTTCCCTTTAGGACAATGTTGTGTAAATCTTTGAAGGACACACCGAAGACCTTTATACTGTGATCTTTTACCCCTTT

>33394_33394_8_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000544149_MLPH_chr2_238427182_ENST00000410032_length(amino acids)=417AA_BP=108
MHRSPFGPGVCVTHGGSCRNALLGKGMTCPCDNASSVFLGFCIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNE
LEKITRRFTMELAKKGFIAGPELISEERSGDSDQTDEDGEPGSEAQAQAQPFGSKKKRLLSVHDFDFEGDSDDSTQPQGHSLHLSSVPEA
RDSPQGLGAGVRTEADVEEEALRRKLEELTSNVSDQETSSEEEEAKDEKAEPNRDKSVGPLPQADPEVGTAAHQTNRQEKSPQDPGDPVQ
YNRTTDEELSELEDRVAVTASEVQQAESEVSDIESRIAALRAAGLTVKPSGKPRRKSNLPIFLPRVAGKLGKRPEDPNADPSSEAKAMAV

--------------------------------------------------------------
>33394_33394_9_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000544149_MLPH_chr2_238427182_ENST00000445024_length(transcript)=1973nt_BP=356nt
GTATATGCTGATCTTGCATGCAGAGTAGACGCTGCACCGGTCTCCTTTTGGTCCCGGTGTCTGTGTCACACACGGCGGGTCCTGCCGAAA
TGCACTTCTAGGAAAGGGAATGACCTGCCCGTGTGATAATGCCTCGTCAGTGTTCTTGGGCTTTTGTATCCGTTACAGCACTGATGTGAG
TGTAGATGAAGTAAAAGCTTTGGCTTCTCTGATGACATACAAGTGTGCAGTGGTTGATGTGCCGTTTGGGGGTGCTAAAGCTGGTGTTAA
GATCAATCCCAAGAACTATACTGATAATGAATTGGAAAAGATCACAAGGAGGTTCACCATGGAGCTAGCAAAAAAGGGCTTTATTGCTGG
GCCTGAACTGATATCTGAAGAGAGAAGTGGAGACAGCGACCAGACAGATGAGGATGGAGAACCTGGCTCAGAGGCCCAGGCCCAGGCCCA
GCCCTTTGGCAGCAAAAAAAAGCGCCTCCTCTCCGTCCACGACTTCGACTTCGAGGGAGACTCAGATGACTCCACTCAGCCTCAAGGTCA
CTCCCTGCACCTGTCCTCAGTCCCTGAGGCCAGGGACAGCCCACAGTCCCTCACAGATGAGTCCTGCTCAGAGAAGGCAGCCCCTCACAA
GGCTGAGGGCCTGGAGGAGGCTGATACTGGGGCCTCTGGGTGCCACTCCCATCCGGAAGAGCAGCCGACCAGCATCTCACCTTCCAGACA
CGGCGCCCTGGCTGAGCTCTGCCCGCCTGGAGGCTCCCACAGGATGGCCCTGGGGACTGCTGCTGCACTCGGGTCGAATGTCATCAGGAA
TGAGCAGCTGCCCCTGCAGTACTTGGCCGATGTGGACACCTCTGATGAGGAAAGCATCCGGGCTCACGTGATGGCCTCCCACCATTCCAA
GCGGAGAGGCCGGGCGTCTTCTGAGAGTCAGATCTTTGAGCTGAATAAGCATATTTCAGCTGTGGAATGCCTGCTGACCTACCTGGAGAA
CACAGTTGTGCCTCCCTTGGCCAAGGGTCTAGGTGCTGGAGTGCGCACGGAGGCCGATGTAGAGGAGGAGGCCCTGAGGAGGAAGCTGGA
GGAGCTGACCAGCAACGTCAGTGACCAGGAGACCTCGTCCGAGGAGGAGGAAGCCAAGGACGAAAAGGCAGAGCCCAACAGGGACAAATC
AGTTGGGCCTCTCCCCCAGGCGGACCCGGAGGTGGGCACGGCTGCCCATCAAACCAACAGACAGGAAAAAAGCCCCCAGGACCCTGGGGA
CCCCGTCCAGTACAACAGGACCACAGATGAGGAGCTGTCAGAGCTGGAGGACAGAGTGGCAGTGACGGCCTCAGAAGTCCAGCAGGCAGA
GAGCGAGGTTTCAGACATTGAATCCAGGATTGCAGCCCTGAGGGCCGCAGGGCTCACGGTGAAGCCCTCGGGAAAGCCCCGGAGGAAGTC
AAACCTCCCGGCTCTTTATGAGGGGACTCTGAGCCTCTGCTCTGAGGATCTGAAACACACACACCCTGACAGTGTAAAATCCAAAAGGAG
CCGCCTGAATCATGTTGCCTCATGTGGAAATCCTTAGTCCGCCGCCACGTGAAGATGGATGTGACTAGAACGGAGGGCGCGGGAGGCTCA
CATCAGAGGAGCTGCTCACATATTTCTCCCTCGAGTGGCTGGGAAACTTGGCAAGAGACCAGAGGACCCAAATGCAGACCCTTCAAGTGA
GGCCAAGGCAATGGCTGTGCCCTATCTTCTGAGAAGAAAGTTCAGTAATTCCCTGAAAAGTCAAGGTAAAGATGATGATTCTTTTGATCG
GAAATCAGTGTACCGAGGCTCGCTGACACAGAGAAACCCCAACGCGAGGAAAGGAATGGCCAGCCACACCTTCGCGAAACCTGTGGTGGC

>33394_33394_9_GLUD1-MLPH_GLUD1_chr10_88834308_ENST00000544149_MLPH_chr2_238427182_ENST00000445024_length(amino acids)=511AA_BP=108
MHRSPFGPGVCVTHGGSCRNALLGKGMTCPCDNASSVFLGFCIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNE
LEKITRRFTMELAKKGFIAGPELISEERSGDSDQTDEDGEPGSEAQAQAQPFGSKKKRLLSVHDFDFEGDSDDSTQPQGHSLHLSSVPEA
RDSPQSLTDESCSEKAAPHKAEGLEEADTGASGCHSHPEEQPTSISPSRHGALAELCPPGGSHRMALGTAAALGSNVIRNEQLPLQYLAD
VDTSDEESIRAHVMASHHSKRRGRASSESQIFELNKHISAVECLLTYLENTVVPPLAKGLGAGVRTEADVEEEALRRKLEELTSNVSDQE
TSSEEEEAKDEKAEPNRDKSVGPLPQADPEVGTAAHQTNRQEKSPQDPGDPVQYNRTTDEELSELEDRVAVTASEVQQAESEVSDIESRI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for GLUD1-MLPH


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GLUD1-MLPH


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GLUD1-MLPH


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource