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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GMEB1-TRNAU1AP (FusionGDB2 ID:33481)

Fusion Gene Summary for GMEB1-TRNAU1AP

check button Fusion gene summary
Fusion gene informationFusion gene name: GMEB1-TRNAU1AP
Fusion gene ID: 33481
HgeneTgene
Gene symbol

GMEB1

TRNAU1AP

Gene ID

10691

54952

Gene nameglucocorticoid modulatory element binding protein 1tRNA selenocysteine 1 associated protein 1
SynonymsP96PIF|PIF96PRO1902|SECP43|TRSPAP1
Cytomap

1p35.3

1p35.3

Type of geneprotein-codingprotein-coding
Descriptionglucocorticoid modulatory element-binding protein 1DNA-binding protein p96PIFPIF p96parvovirus initiation factor p96tRNA selenocysteine 1-associated protein 1tRNA selenocysteine associated protein (SECP43)tRNA selenocysteine-associated protein 1
Modification date2020032020200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000480454, ENST00000294409, 
ENST00000361872, ENST00000373816, 
ENST00000373830, ENST00000495995, 
Fusion gene scores* DoF score7 X 7 X 6=2948 X 13 X 7=728
# samples 1215
** MAII scorelog2(12/294*10)=-1.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/728*10)=-2.27897594970282
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GMEB1 [Title/Abstract] AND TRNAU1AP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGMEB1(28995351)-TRNAU1AP(28897687), # samples:3
GMEB1(28995351)-TRNAU1AP(28897688), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across GMEB1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TRNAU1AP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-DK-A6B2-01AGMEB1chr1

29019557

-TRNAU1APchr1

28887145

+
ChimerDB4BLCATCGA-DK-A6B2-01AGMEB1chr1

29019557

+TRNAU1APchr1

28887145

+
ChimerDB4BLCATCGA-DK-A6B2GMEB1chr1

29019557

+TRNAU1APchr1

28887144

+
ChimerDB4BRCATCGA-A7-A26G-01AGMEB1chr1

28995351

+TRNAU1APchr1

28897688

+
ChimerDB4BRCATCGA-A7-A26GGMEB1chr1

28995351

+TRNAU1APchr1

28897687

+
ChimerDB4OVTCGA-24-2023-01AGMEB1chr1

28995351

-TRNAU1APchr1

28897688

+
ChimerDB4OVTCGA-24-2023-01AGMEB1chr1

28995351

+TRNAU1APchr1

28897688

+
ChimerDB4OVTCGA-24-2023-01AGMEB1chr1

28995351

+TRNAU1APchr1

28898379

+
ChimerDB4OVTCGA-24-2023GMEB1chr1

28995351

+TRNAU1APchr1

28897687

+
ChimerDB4OVTCGA-24-2023GMEB1chr1

28995351

+TRNAU1APchr1

28898378

+
ChimerDB4READTCGA-AG-A036GMEB1chr1

28995351

+TRNAU1APchr1

28897687

+
ChimerDB4READTCGA-AG-A036GMEB1chr1

28995351

+TRNAU1APchr1

28898378

+


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Fusion Gene ORF analysis for GMEB1-TRNAU1AP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000480454ENST00000373830GMEB1chr1

29019557

+TRNAU1APchr1

28887145

+
3UTR-3CDSENST00000480454ENST00000373830GMEB1chr1

29019557

+TRNAU1APchr1

28887144

+
3UTR-3UTRENST00000480454ENST00000495995GMEB1chr1

29019557

+TRNAU1APchr1

28887145

+
3UTR-3UTRENST00000480454ENST00000495995GMEB1chr1

29019557

+TRNAU1APchr1

28887144

+
5CDS-3UTRENST00000294409ENST00000495995GMEB1chr1

29019557

+TRNAU1APchr1

28887145

+
5CDS-3UTRENST00000294409ENST00000495995GMEB1chr1

29019557

+TRNAU1APchr1

28887144

+
5CDS-3UTRENST00000361872ENST00000495995GMEB1chr1

29019557

+TRNAU1APchr1

28887145

+
5CDS-3UTRENST00000361872ENST00000495995GMEB1chr1

29019557

+TRNAU1APchr1

28887144

+
5CDS-3UTRENST00000373816ENST00000495995GMEB1chr1

29019557

+TRNAU1APchr1

28887145

+
5CDS-3UTRENST00000373816ENST00000495995GMEB1chr1

29019557

+TRNAU1APchr1

28887144

+
5UTR-3CDSENST00000294409ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28897688

+
5UTR-3CDSENST00000294409ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28897687

+
5UTR-3CDSENST00000294409ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28898379

+
5UTR-3CDSENST00000294409ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28898378

+
5UTR-3CDSENST00000361872ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28897688

+
5UTR-3CDSENST00000361872ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28897687

+
5UTR-3CDSENST00000361872ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28898379

+
5UTR-3CDSENST00000361872ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28898378

+
5UTR-3CDSENST00000373816ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28897688

+
5UTR-3CDSENST00000373816ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28897687

+
5UTR-3CDSENST00000373816ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28898379

+
5UTR-3CDSENST00000373816ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28898378

+
5UTR-intronENST00000294409ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28897688

+
5UTR-intronENST00000294409ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28897687

+
5UTR-intronENST00000294409ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28898379

+
5UTR-intronENST00000294409ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28898378

+
5UTR-intronENST00000361872ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28897688

+
5UTR-intronENST00000361872ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28897687

+
5UTR-intronENST00000361872ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28898379

+
5UTR-intronENST00000361872ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28898378

+
5UTR-intronENST00000373816ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28897688

+
5UTR-intronENST00000373816ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28897687

+
5UTR-intronENST00000373816ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28898379

+
5UTR-intronENST00000373816ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28898378

+
In-frameENST00000294409ENST00000373830GMEB1chr1

29019557

+TRNAU1APchr1

28887145

+
In-frameENST00000294409ENST00000373830GMEB1chr1

29019557

+TRNAU1APchr1

28887144

+
In-frameENST00000361872ENST00000373830GMEB1chr1

29019557

+TRNAU1APchr1

28887145

+
In-frameENST00000361872ENST00000373830GMEB1chr1

29019557

+TRNAU1APchr1

28887144

+
In-frameENST00000373816ENST00000373830GMEB1chr1

29019557

+TRNAU1APchr1

28887145

+
In-frameENST00000373816ENST00000373830GMEB1chr1

29019557

+TRNAU1APchr1

28887144

+
intron-3CDSENST00000480454ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28897688

+
intron-3CDSENST00000480454ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28897687

+
intron-3CDSENST00000480454ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28898379

+
intron-3CDSENST00000480454ENST00000373830GMEB1chr1

28995351

+TRNAU1APchr1

28898378

+
intron-intronENST00000480454ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28897688

+
intron-intronENST00000480454ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28897687

+
intron-intronENST00000480454ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28898379

+
intron-intronENST00000480454ENST00000495995GMEB1chr1

28995351

+TRNAU1APchr1

28898378

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000373816GMEB1chr129019557+ENST00000373830TRNAU1APchr128887144+22205781381316392
ENST00000361872GMEB1chr129019557+ENST00000373830TRNAU1APchr128887144+2171529891267392
ENST00000294409GMEB1chr129019557+ENST00000373830TRNAU1APchr128887144+2202560901298402
ENST00000373816GMEB1chr129019557+ENST00000373830TRNAU1APchr128887145+22205781381316392
ENST00000361872GMEB1chr129019557+ENST00000373830TRNAU1APchr128887145+2171529891267392
ENST00000294409GMEB1chr129019557+ENST00000373830TRNAU1APchr128887145+2202560901298402

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000373816ENST00000373830GMEB1chr129019557+TRNAU1APchr128887144+0.0014094050.9985905
ENST00000361872ENST00000373830GMEB1chr129019557+TRNAU1APchr128887144+0.0013924060.9986076
ENST00000294409ENST00000373830GMEB1chr129019557+TRNAU1APchr128887144+0.0015877280.99841225
ENST00000373816ENST00000373830GMEB1chr129019557+TRNAU1APchr128887145+0.0014094050.9985905
ENST00000361872ENST00000373830GMEB1chr129019557+TRNAU1APchr128887145+0.0013924060.9986076
ENST00000294409ENST00000373830GMEB1chr129019557+TRNAU1APchr128887145+0.0015877280.99841225

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Fusion Genomic Features for GMEB1-TRNAU1AP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
GMEB1chr128995351+TRNAU1APchr128898378+7.00E-080.9999999
GMEB1chr128995351+TRNAU1APchr128898378+7.00E-080.9999999
GMEB1chr129019557+TRNAU1APchr128887144+5.06E-131
GMEB1chr128995351+TRNAU1APchr128897687+3.29E-101
GMEB1chr128995351+TRNAU1APchr128897687+3.29E-101
GMEB1chr129019557+TRNAU1APchr128887144+5.06E-131
GMEB1chr128995351+TRNAU1APchr128897687+3.29E-101
GMEB1chr128995351+TRNAU1APchr128898378+7.00E-080.9999999
GMEB1chr128995351+TRNAU1APchr128898378+7.00E-080.9999999
GMEB1chr129019557+TRNAU1APchr128887144+5.06E-131
GMEB1chr128995351+TRNAU1APchr128897687+3.29E-101
GMEB1chr128995351+TRNAU1APchr128897687+3.29E-101
GMEB1chr129019557+TRNAU1APchr128887144+5.06E-131
GMEB1chr128995351+TRNAU1APchr128897687+3.29E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for GMEB1-TRNAU1AP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:28995351/chr1:28897687)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTRNAU1APchr1:29019557chr1:28887144ENST0000037383019185_22541288.0Compositional biasNote=Tyr-rich
TgeneTRNAU1APchr1:29019557chr1:28887145ENST0000037383019185_22541288.0Compositional biasNote=Tyr-rich
TgeneTRNAU1APchr1:29019557chr1:28887144ENST000003738301996_17541288.0DomainRRM 2
TgeneTRNAU1APchr1:29019557chr1:28887145ENST000003738301996_17541288.0DomainRRM 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGMEB1chr1:29019557chr1:28887144ENST00000294409+510321_367156574.0Coiled coilOntology_term=ECO:0000255
HgeneGMEB1chr1:29019557chr1:28887144ENST00000361872+510321_367146564.0Coiled coilOntology_term=ECO:0000255
HgeneGMEB1chr1:29019557chr1:28887144ENST00000373816+510321_367146564.0Coiled coilOntology_term=ECO:0000255
HgeneGMEB1chr1:29019557chr1:28887145ENST00000294409+510321_367156574.0Coiled coilOntology_term=ECO:0000255
HgeneGMEB1chr1:29019557chr1:28887145ENST00000361872+510321_367146564.0Coiled coilOntology_term=ECO:0000255
HgeneGMEB1chr1:29019557chr1:28887145ENST00000373816+510321_367146564.0Coiled coilOntology_term=ECO:0000255
HgeneGMEB1chr1:29019557chr1:28887144ENST00000294409+51082_166156574.0DomainSAND
HgeneGMEB1chr1:29019557chr1:28887144ENST00000361872+51082_166146564.0DomainSAND
HgeneGMEB1chr1:29019557chr1:28887144ENST00000373816+51082_166146564.0DomainSAND
HgeneGMEB1chr1:29019557chr1:28887145ENST00000294409+51082_166156574.0DomainSAND
HgeneGMEB1chr1:29019557chr1:28887145ENST00000361872+51082_166146564.0DomainSAND
HgeneGMEB1chr1:29019557chr1:28887145ENST00000373816+51082_166146564.0DomainSAND
TgeneTRNAU1APchr1:29019557chr1:28887144ENST00000373830193_8641288.0DomainRRM 1
TgeneTRNAU1APchr1:29019557chr1:28887145ENST00000373830193_8641288.0DomainRRM 1


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Fusion Gene Sequence for GMEB1-TRNAU1AP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>33481_33481_1_GMEB1-TRNAU1AP_GMEB1_chr1_29019557_ENST00000294409_TRNAU1AP_chr1_28887144_ENST00000373830_length(transcript)=2202nt_BP=560nt
GCGCATGCTCCGTCGCCTGCCCGCCCTGGCCGCTCGCCGCCCGCCCGCCCGACGGAGACGCAGTCCCAGCTATCTGACTTCATGTGAAAG
ATGGCTAATGCAGAAGTGAGTGTCCCAGTGGGGGATGTGGTTGTGGTACCTACTGAAGGAAATGAAGGGGAGAATCCTGAAGACACTAAA
ACCCAAGTGATTTTGCAGTTACAGCCTGTGCAACAAGGTTTGTTTATCGATGGACACTTTTACAACAGGATTTATGAAGCTGGGTCGGAG
AACAACACGGCAGTTGTAGCAGTAGAAACTCACACGATACACAAAATTGAAGAAGGGATTGATACAGGCACTATAGAAGCAAATGAGGAT
ATGGAAATTGCTTACCCCATAACTTGTGGGGAGAGCAAAGCCATCCTCCTCTGGAAGAAGTTTGTATGTCCAGGAATAAACGTGAAGTGT
GTCAAGTTCAATGATCAGTTGATCAGCCCCAAGCACTTTGTTCATCTGGCTGGCAAGTCCACTCTGAAGGACTGGAAGAGAGCTATTCGT
CTGGGTGGGATCATGCTCAGGATCCCAGCTGGCTACTGCTTTGTAGAATTTGCAGATTTGGCCACAGCTGAGAAGTGTTTGCATAAAATT
AATGGGAAACCCCTTCCAGGAGCCACACCTGCGAAACGTTTTAAACTGAACTATGCCACTTACGGGAAACAACCAGATAACAGCCCTGAG
TATTCCCTCTTTGTGGGGGACCTGACCCCGGACGTGGATGATGGCATGCTGTATGAATTCTTCGTCAAAGTCTACCCCTCCTGTCGGGGA
GGCAAGGTGGTTTTGGACCAGACAGGCGTGTCTAAGGGTTATGGTTTTGTGAAATTCACAGATGAACTGGAACAGAAGCGAGCCCTGACG
GAGTGCCAGGGAGCAGTGGGACTGGGGTCTAAGCCTGTGCGGCTGAGCGTGGCAATCCCTAAAGCGAGCCGTGTAAAGCCAGTGGAATAT
AGTCAGATGTACAGTTATAGCTACAACCAGTATTATCAGCAGTACCAGAACTACTATGCTCAGTGGGGCTATGACCAGAACACAGGCAGC
TACAGCTACAGTTACCCCCAGTATGGCTATACCCAGAGCACCATGCAGACATATGAAGAAGTTGGAGATGATGCATTGGAAGACCCCATG
CCACAGCTGGATGTGACTGAGGCCAACAAGGAGTTCATGGAACAGAGTGAGGAGCTGTATGACGCTCTGATGGACTGTCACTGGCAGCCC
CTGGACACAGTGTCTTCAGAGATCCCTGCCATGATGTAGCCAGGCCAAAGGACAAGCCAGGTTGCATGATGTGAGGGAGATGAGAGACTC
CTTTTTAAAAATTGTGAAACCTTTTTGGAAATATGATTTGTAAGATTTTAATAATGACTGTTTTTGGAGATCATGAATGTTTCTACAACA
CTGCTGCATTCATTTGACCATTTGAGTTTGAAGACCAAGGGAACAACTTTTAAACAAGGTTCAAATTGGTTTCCTTCACAGGAATCCTTT
GTCCAGGTAGTTATCCACATAGGACAGTTTGGGATTATCCAAAACTGGGATGAGCAGCTTGGGATAATTCACACACTAAAGCCTGAGTTC
AAGGTTTCTCAGTTGACAGGTAGGTATGTAAATCAGGGTTCTCTGGAGTATTTGTAGGACCTGCCATATTTGAGTCCTAACTTGGTGCAA
GTCTGGCAGCTAGGTAGAAAAGGCACTCTAGCAGGTGTGGTAGGAGCACGCCCCAGAAGGTAGAATGTGGTGGGGTGTGATGGAACAGGC
CAGTTGGCCTAAGAATTAGTACTTGCTCTAATAATGGGTTTCATCTATTTTCATGAGTTGCAGCATCTGCATATACAAGGCCTGGATCAC
TTTAGGATCAATATTTTGACACGGGAGAAGGCAGCTCAGAAAGGATTAAGGAAGATAGCTCAAAGCCAAAGCAGACCCTCCGTGTGAACT
TTATACTGCTCACTTCCGTGTTTCCCAAGTAAATGGGGAAACTGTCCAACCTTGTCATGTGTTGGGACTTACTGCTTGAGGCAAAGCATT
CATCCTACATCATAAAAAATCTCCAAAGATCTCTTTAAGGGCTGGGCATGGTGGCTCACTTTGGGAGATGGATTGCTTGAGCTCGGGAAG

>33481_33481_1_GMEB1-TRNAU1AP_GMEB1_chr1_29019557_ENST00000294409_TRNAU1AP_chr1_28887144_ENST00000373830_length(amino acids)=402AA_BP=156
MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGLFIDGHFYNRIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANED
MEIAYPITCGESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRIPAGYCFVEFADLATAEKCLHKI
NGKPLPGATPAKRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDQTGVSKGYGFVKFTDELEQKRALT
ECQGAVGLGSKPVRLSVAIPKASRVKPVEYSQMYSYSYNQYYQQYQNYYAQWGYDQNTGSYSYSYPQYGYTQSTMQTYEEVGDDALEDPM

--------------------------------------------------------------
>33481_33481_2_GMEB1-TRNAU1AP_GMEB1_chr1_29019557_ENST00000294409_TRNAU1AP_chr1_28887145_ENST00000373830_length(transcript)=2202nt_BP=560nt
GCGCATGCTCCGTCGCCTGCCCGCCCTGGCCGCTCGCCGCCCGCCCGCCCGACGGAGACGCAGTCCCAGCTATCTGACTTCATGTGAAAG
ATGGCTAATGCAGAAGTGAGTGTCCCAGTGGGGGATGTGGTTGTGGTACCTACTGAAGGAAATGAAGGGGAGAATCCTGAAGACACTAAA
ACCCAAGTGATTTTGCAGTTACAGCCTGTGCAACAAGGTTTGTTTATCGATGGACACTTTTACAACAGGATTTATGAAGCTGGGTCGGAG
AACAACACGGCAGTTGTAGCAGTAGAAACTCACACGATACACAAAATTGAAGAAGGGATTGATACAGGCACTATAGAAGCAAATGAGGAT
ATGGAAATTGCTTACCCCATAACTTGTGGGGAGAGCAAAGCCATCCTCCTCTGGAAGAAGTTTGTATGTCCAGGAATAAACGTGAAGTGT
GTCAAGTTCAATGATCAGTTGATCAGCCCCAAGCACTTTGTTCATCTGGCTGGCAAGTCCACTCTGAAGGACTGGAAGAGAGCTATTCGT
CTGGGTGGGATCATGCTCAGGATCCCAGCTGGCTACTGCTTTGTAGAATTTGCAGATTTGGCCACAGCTGAGAAGTGTTTGCATAAAATT
AATGGGAAACCCCTTCCAGGAGCCACACCTGCGAAACGTTTTAAACTGAACTATGCCACTTACGGGAAACAACCAGATAACAGCCCTGAG
TATTCCCTCTTTGTGGGGGACCTGACCCCGGACGTGGATGATGGCATGCTGTATGAATTCTTCGTCAAAGTCTACCCCTCCTGTCGGGGA
GGCAAGGTGGTTTTGGACCAGACAGGCGTGTCTAAGGGTTATGGTTTTGTGAAATTCACAGATGAACTGGAACAGAAGCGAGCCCTGACG
GAGTGCCAGGGAGCAGTGGGACTGGGGTCTAAGCCTGTGCGGCTGAGCGTGGCAATCCCTAAAGCGAGCCGTGTAAAGCCAGTGGAATAT
AGTCAGATGTACAGTTATAGCTACAACCAGTATTATCAGCAGTACCAGAACTACTATGCTCAGTGGGGCTATGACCAGAACACAGGCAGC
TACAGCTACAGTTACCCCCAGTATGGCTATACCCAGAGCACCATGCAGACATATGAAGAAGTTGGAGATGATGCATTGGAAGACCCCATG
CCACAGCTGGATGTGACTGAGGCCAACAAGGAGTTCATGGAACAGAGTGAGGAGCTGTATGACGCTCTGATGGACTGTCACTGGCAGCCC
CTGGACACAGTGTCTTCAGAGATCCCTGCCATGATGTAGCCAGGCCAAAGGACAAGCCAGGTTGCATGATGTGAGGGAGATGAGAGACTC
CTTTTTAAAAATTGTGAAACCTTTTTGGAAATATGATTTGTAAGATTTTAATAATGACTGTTTTTGGAGATCATGAATGTTTCTACAACA
CTGCTGCATTCATTTGACCATTTGAGTTTGAAGACCAAGGGAACAACTTTTAAACAAGGTTCAAATTGGTTTCCTTCACAGGAATCCTTT
GTCCAGGTAGTTATCCACATAGGACAGTTTGGGATTATCCAAAACTGGGATGAGCAGCTTGGGATAATTCACACACTAAAGCCTGAGTTC
AAGGTTTCTCAGTTGACAGGTAGGTATGTAAATCAGGGTTCTCTGGAGTATTTGTAGGACCTGCCATATTTGAGTCCTAACTTGGTGCAA
GTCTGGCAGCTAGGTAGAAAAGGCACTCTAGCAGGTGTGGTAGGAGCACGCCCCAGAAGGTAGAATGTGGTGGGGTGTGATGGAACAGGC
CAGTTGGCCTAAGAATTAGTACTTGCTCTAATAATGGGTTTCATCTATTTTCATGAGTTGCAGCATCTGCATATACAAGGCCTGGATCAC
TTTAGGATCAATATTTTGACACGGGAGAAGGCAGCTCAGAAAGGATTAAGGAAGATAGCTCAAAGCCAAAGCAGACCCTCCGTGTGAACT
TTATACTGCTCACTTCCGTGTTTCCCAAGTAAATGGGGAAACTGTCCAACCTTGTCATGTGTTGGGACTTACTGCTTGAGGCAAAGCATT
CATCCTACATCATAAAAAATCTCCAAAGATCTCTTTAAGGGCTGGGCATGGTGGCTCACTTTGGGAGATGGATTGCTTGAGCTCGGGAAG

>33481_33481_2_GMEB1-TRNAU1AP_GMEB1_chr1_29019557_ENST00000294409_TRNAU1AP_chr1_28887145_ENST00000373830_length(amino acids)=402AA_BP=156
MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGLFIDGHFYNRIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANED
MEIAYPITCGESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRIPAGYCFVEFADLATAEKCLHKI
NGKPLPGATPAKRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDQTGVSKGYGFVKFTDELEQKRALT
ECQGAVGLGSKPVRLSVAIPKASRVKPVEYSQMYSYSYNQYYQQYQNYYAQWGYDQNTGSYSYSYPQYGYTQSTMQTYEEVGDDALEDPM

--------------------------------------------------------------
>33481_33481_3_GMEB1-TRNAU1AP_GMEB1_chr1_29019557_ENST00000361872_TRNAU1AP_chr1_28887144_ENST00000373830_length(transcript)=2171nt_BP=529nt
CTGCGCATGCTCCGTCGCCTGCCCGCCCTGGCCGCTCGCCGCCCGCCCGCCCGACGGAGACGTCCCAGCTATCTGACTTCATGTGAAAGA
TGGCTAATGCAGAAGTGAGTGTCCCAGTGGGGGATGTGGTTGTGGTACCTACTGAAGGAAATGAAGGGGAGAATCCTGAAGACACTAAAA
CCCAAGTGATTTTGCAGTTACAGCCTGTGCAACAAGGGATTTATGAAGCTGGGTCGGAGAACAACACGGCAGTTGTAGCAGTAGAAACTC
ACACGATACACAAAATTGAAGAAGGGATTGATACAGGCACTATAGAAGCAAATGAGGATATGGAAATTGCTTACCCCATAACTTGTGGGG
AGAGCAAAGCCATCCTCCTCTGGAAGAAGTTTGTATGTCCAGGAATAAACGTGAAGTGTGTCAAGTTCAATGATCAGTTGATCAGCCCCA
AGCACTTTGTTCATCTGGCTGGCAAGTCCACTCTGAAGGACTGGAAGAGAGCTATTCGTCTGGGTGGGATCATGCTCAGGATCCCAGCTG
GCTACTGCTTTGTAGAATTTGCAGATTTGGCCACAGCTGAGAAGTGTTTGCATAAAATTAATGGGAAACCCCTTCCAGGAGCCACACCTG
CGAAACGTTTTAAACTGAACTATGCCACTTACGGGAAACAACCAGATAACAGCCCTGAGTATTCCCTCTTTGTGGGGGACCTGACCCCGG
ACGTGGATGATGGCATGCTGTATGAATTCTTCGTCAAAGTCTACCCCTCCTGTCGGGGAGGCAAGGTGGTTTTGGACCAGACAGGCGTGT
CTAAGGGTTATGGTTTTGTGAAATTCACAGATGAACTGGAACAGAAGCGAGCCCTGACGGAGTGCCAGGGAGCAGTGGGACTGGGGTCTA
AGCCTGTGCGGCTGAGCGTGGCAATCCCTAAAGCGAGCCGTGTAAAGCCAGTGGAATATAGTCAGATGTACAGTTATAGCTACAACCAGT
ATTATCAGCAGTACCAGAACTACTATGCTCAGTGGGGCTATGACCAGAACACAGGCAGCTACAGCTACAGTTACCCCCAGTATGGCTATA
CCCAGAGCACCATGCAGACATATGAAGAAGTTGGAGATGATGCATTGGAAGACCCCATGCCACAGCTGGATGTGACTGAGGCCAACAAGG
AGTTCATGGAACAGAGTGAGGAGCTGTATGACGCTCTGATGGACTGTCACTGGCAGCCCCTGGACACAGTGTCTTCAGAGATCCCTGCCA
TGATGTAGCCAGGCCAAAGGACAAGCCAGGTTGCATGATGTGAGGGAGATGAGAGACTCCTTTTTAAAAATTGTGAAACCTTTTTGGAAA
TATGATTTGTAAGATTTTAATAATGACTGTTTTTGGAGATCATGAATGTTTCTACAACACTGCTGCATTCATTTGACCATTTGAGTTTGA
AGACCAAGGGAACAACTTTTAAACAAGGTTCAAATTGGTTTCCTTCACAGGAATCCTTTGTCCAGGTAGTTATCCACATAGGACAGTTTG
GGATTATCCAAAACTGGGATGAGCAGCTTGGGATAATTCACACACTAAAGCCTGAGTTCAAGGTTTCTCAGTTGACAGGTAGGTATGTAA
ATCAGGGTTCTCTGGAGTATTTGTAGGACCTGCCATATTTGAGTCCTAACTTGGTGCAAGTCTGGCAGCTAGGTAGAAAAGGCACTCTAG
CAGGTGTGGTAGGAGCACGCCCCAGAAGGTAGAATGTGGTGGGGTGTGATGGAACAGGCCAGTTGGCCTAAGAATTAGTACTTGCTCTAA
TAATGGGTTTCATCTATTTTCATGAGTTGCAGCATCTGCATATACAAGGCCTGGATCACTTTAGGATCAATATTTTGACACGGGAGAAGG
CAGCTCAGAAAGGATTAAGGAAGATAGCTCAAAGCCAAAGCAGACCCTCCGTGTGAACTTTATACTGCTCACTTCCGTGTTTCCCAAGTA
AATGGGGAAACTGTCCAACCTTGTCATGTGTTGGGACTTACTGCTTGAGGCAAAGCATTCATCCTACATCATAAAAAATCTCCAAAGATC
TCTTTAAGGGCTGGGCATGGTGGCTCACTTTGGGAGATGGATTGCTTGAGCTCGGGAAGAGACCAGTTCGGTCTCTACAAAAAAATACAA

>33481_33481_3_GMEB1-TRNAU1AP_GMEB1_chr1_29019557_ENST00000361872_TRNAU1AP_chr1_28887144_ENST00000373830_length(amino acids)=392AA_BP=146
MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANEDMEIAYPITCG
ESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRIPAGYCFVEFADLATAEKCLHKINGKPLPGATP
AKRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDQTGVSKGYGFVKFTDELEQKRALTECQGAVGLGS
KPVRLSVAIPKASRVKPVEYSQMYSYSYNQYYQQYQNYYAQWGYDQNTGSYSYSYPQYGYTQSTMQTYEEVGDDALEDPMPQLDVTEANK

--------------------------------------------------------------
>33481_33481_4_GMEB1-TRNAU1AP_GMEB1_chr1_29019557_ENST00000361872_TRNAU1AP_chr1_28887145_ENST00000373830_length(transcript)=2171nt_BP=529nt
CTGCGCATGCTCCGTCGCCTGCCCGCCCTGGCCGCTCGCCGCCCGCCCGCCCGACGGAGACGTCCCAGCTATCTGACTTCATGTGAAAGA
TGGCTAATGCAGAAGTGAGTGTCCCAGTGGGGGATGTGGTTGTGGTACCTACTGAAGGAAATGAAGGGGAGAATCCTGAAGACACTAAAA
CCCAAGTGATTTTGCAGTTACAGCCTGTGCAACAAGGGATTTATGAAGCTGGGTCGGAGAACAACACGGCAGTTGTAGCAGTAGAAACTC
ACACGATACACAAAATTGAAGAAGGGATTGATACAGGCACTATAGAAGCAAATGAGGATATGGAAATTGCTTACCCCATAACTTGTGGGG
AGAGCAAAGCCATCCTCCTCTGGAAGAAGTTTGTATGTCCAGGAATAAACGTGAAGTGTGTCAAGTTCAATGATCAGTTGATCAGCCCCA
AGCACTTTGTTCATCTGGCTGGCAAGTCCACTCTGAAGGACTGGAAGAGAGCTATTCGTCTGGGTGGGATCATGCTCAGGATCCCAGCTG
GCTACTGCTTTGTAGAATTTGCAGATTTGGCCACAGCTGAGAAGTGTTTGCATAAAATTAATGGGAAACCCCTTCCAGGAGCCACACCTG
CGAAACGTTTTAAACTGAACTATGCCACTTACGGGAAACAACCAGATAACAGCCCTGAGTATTCCCTCTTTGTGGGGGACCTGACCCCGG
ACGTGGATGATGGCATGCTGTATGAATTCTTCGTCAAAGTCTACCCCTCCTGTCGGGGAGGCAAGGTGGTTTTGGACCAGACAGGCGTGT
CTAAGGGTTATGGTTTTGTGAAATTCACAGATGAACTGGAACAGAAGCGAGCCCTGACGGAGTGCCAGGGAGCAGTGGGACTGGGGTCTA
AGCCTGTGCGGCTGAGCGTGGCAATCCCTAAAGCGAGCCGTGTAAAGCCAGTGGAATATAGTCAGATGTACAGTTATAGCTACAACCAGT
ATTATCAGCAGTACCAGAACTACTATGCTCAGTGGGGCTATGACCAGAACACAGGCAGCTACAGCTACAGTTACCCCCAGTATGGCTATA
CCCAGAGCACCATGCAGACATATGAAGAAGTTGGAGATGATGCATTGGAAGACCCCATGCCACAGCTGGATGTGACTGAGGCCAACAAGG
AGTTCATGGAACAGAGTGAGGAGCTGTATGACGCTCTGATGGACTGTCACTGGCAGCCCCTGGACACAGTGTCTTCAGAGATCCCTGCCA
TGATGTAGCCAGGCCAAAGGACAAGCCAGGTTGCATGATGTGAGGGAGATGAGAGACTCCTTTTTAAAAATTGTGAAACCTTTTTGGAAA
TATGATTTGTAAGATTTTAATAATGACTGTTTTTGGAGATCATGAATGTTTCTACAACACTGCTGCATTCATTTGACCATTTGAGTTTGA
AGACCAAGGGAACAACTTTTAAACAAGGTTCAAATTGGTTTCCTTCACAGGAATCCTTTGTCCAGGTAGTTATCCACATAGGACAGTTTG
GGATTATCCAAAACTGGGATGAGCAGCTTGGGATAATTCACACACTAAAGCCTGAGTTCAAGGTTTCTCAGTTGACAGGTAGGTATGTAA
ATCAGGGTTCTCTGGAGTATTTGTAGGACCTGCCATATTTGAGTCCTAACTTGGTGCAAGTCTGGCAGCTAGGTAGAAAAGGCACTCTAG
CAGGTGTGGTAGGAGCACGCCCCAGAAGGTAGAATGTGGTGGGGTGTGATGGAACAGGCCAGTTGGCCTAAGAATTAGTACTTGCTCTAA
TAATGGGTTTCATCTATTTTCATGAGTTGCAGCATCTGCATATACAAGGCCTGGATCACTTTAGGATCAATATTTTGACACGGGAGAAGG
CAGCTCAGAAAGGATTAAGGAAGATAGCTCAAAGCCAAAGCAGACCCTCCGTGTGAACTTTATACTGCTCACTTCCGTGTTTCCCAAGTA
AATGGGGAAACTGTCCAACCTTGTCATGTGTTGGGACTTACTGCTTGAGGCAAAGCATTCATCCTACATCATAAAAAATCTCCAAAGATC
TCTTTAAGGGCTGGGCATGGTGGCTCACTTTGGGAGATGGATTGCTTGAGCTCGGGAAGAGACCAGTTCGGTCTCTACAAAAAAATACAA

>33481_33481_4_GMEB1-TRNAU1AP_GMEB1_chr1_29019557_ENST00000361872_TRNAU1AP_chr1_28887145_ENST00000373830_length(amino acids)=392AA_BP=146
MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANEDMEIAYPITCG
ESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRIPAGYCFVEFADLATAEKCLHKINGKPLPGATP
AKRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDQTGVSKGYGFVKFTDELEQKRALTECQGAVGLGS
KPVRLSVAIPKASRVKPVEYSQMYSYSYNQYYQQYQNYYAQWGYDQNTGSYSYSYPQYGYTQSTMQTYEEVGDDALEDPMPQLDVTEANK

--------------------------------------------------------------
>33481_33481_5_GMEB1-TRNAU1AP_GMEB1_chr1_29019557_ENST00000373816_TRNAU1AP_chr1_28887144_ENST00000373830_length(transcript)=2220nt_BP=578nt
AAGCCCGGCCTGGCGGCGGCGGTGGCGGTAGCTGCCGTGGCGGCCTCTGCGCATGCTCCGTCGCCTGCCCGCCCTGGCCGCTCGCCGCCC
GCCCGCCCGACGGAGACGCAGTCCCAGCTATCTGACTTCATGTGAAAGATGGCTAATGCAGAAGTGAGTGTCCCAGTGGGGGATGTGGTT
GTGGTACCTACTGAAGGAAATGAAGGGGAGAATCCTGAAGACACTAAAACCCAAGTGATTTTGCAGTTACAGCCTGTGCAACAAGGGATT
TATGAAGCTGGGTCGGAGAACAACACGGCAGTTGTAGCAGTAGAAACTCACACGATACACAAAATTGAAGAAGGGATTGATACAGGCACT
ATAGAAGCAAATGAGGATATGGAAATTGCTTACCCCATAACTTGTGGGGAGAGCAAAGCCATCCTCCTCTGGAAGAAGTTTGTATGTCCA
GGAATAAACGTGAAGTGTGTCAAGTTCAATGATCAGTTGATCAGCCCCAAGCACTTTGTTCATCTGGCTGGCAAGTCCACTCTGAAGGAC
TGGAAGAGAGCTATTCGTCTGGGTGGGATCATGCTCAGGATCCCAGCTGGCTACTGCTTTGTAGAATTTGCAGATTTGGCCACAGCTGAG
AAGTGTTTGCATAAAATTAATGGGAAACCCCTTCCAGGAGCCACACCTGCGAAACGTTTTAAACTGAACTATGCCACTTACGGGAAACAA
CCAGATAACAGCCCTGAGTATTCCCTCTTTGTGGGGGACCTGACCCCGGACGTGGATGATGGCATGCTGTATGAATTCTTCGTCAAAGTC
TACCCCTCCTGTCGGGGAGGCAAGGTGGTTTTGGACCAGACAGGCGTGTCTAAGGGTTATGGTTTTGTGAAATTCACAGATGAACTGGAA
CAGAAGCGAGCCCTGACGGAGTGCCAGGGAGCAGTGGGACTGGGGTCTAAGCCTGTGCGGCTGAGCGTGGCAATCCCTAAAGCGAGCCGT
GTAAAGCCAGTGGAATATAGTCAGATGTACAGTTATAGCTACAACCAGTATTATCAGCAGTACCAGAACTACTATGCTCAGTGGGGCTAT
GACCAGAACACAGGCAGCTACAGCTACAGTTACCCCCAGTATGGCTATACCCAGAGCACCATGCAGACATATGAAGAAGTTGGAGATGAT
GCATTGGAAGACCCCATGCCACAGCTGGATGTGACTGAGGCCAACAAGGAGTTCATGGAACAGAGTGAGGAGCTGTATGACGCTCTGATG
GACTGTCACTGGCAGCCCCTGGACACAGTGTCTTCAGAGATCCCTGCCATGATGTAGCCAGGCCAAAGGACAAGCCAGGTTGCATGATGT
GAGGGAGATGAGAGACTCCTTTTTAAAAATTGTGAAACCTTTTTGGAAATATGATTTGTAAGATTTTAATAATGACTGTTTTTGGAGATC
ATGAATGTTTCTACAACACTGCTGCATTCATTTGACCATTTGAGTTTGAAGACCAAGGGAACAACTTTTAAACAAGGTTCAAATTGGTTT
CCTTCACAGGAATCCTTTGTCCAGGTAGTTATCCACATAGGACAGTTTGGGATTATCCAAAACTGGGATGAGCAGCTTGGGATAATTCAC
ACACTAAAGCCTGAGTTCAAGGTTTCTCAGTTGACAGGTAGGTATGTAAATCAGGGTTCTCTGGAGTATTTGTAGGACCTGCCATATTTG
AGTCCTAACTTGGTGCAAGTCTGGCAGCTAGGTAGAAAAGGCACTCTAGCAGGTGTGGTAGGAGCACGCCCCAGAAGGTAGAATGTGGTG
GGGTGTGATGGAACAGGCCAGTTGGCCTAAGAATTAGTACTTGCTCTAATAATGGGTTTCATCTATTTTCATGAGTTGCAGCATCTGCAT
ATACAAGGCCTGGATCACTTTAGGATCAATATTTTGACACGGGAGAAGGCAGCTCAGAAAGGATTAAGGAAGATAGCTCAAAGCCAAAGC
AGACCCTCCGTGTGAACTTTATACTGCTCACTTCCGTGTTTCCCAAGTAAATGGGGAAACTGTCCAACCTTGTCATGTGTTGGGACTTAC
TGCTTGAGGCAAAGCATTCATCCTACATCATAAAAAATCTCCAAAGATCTCTTTAAGGGCTGGGCATGGTGGCTCACTTTGGGAGATGGA

>33481_33481_5_GMEB1-TRNAU1AP_GMEB1_chr1_29019557_ENST00000373816_TRNAU1AP_chr1_28887144_ENST00000373830_length(amino acids)=392AA_BP=146
MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANEDMEIAYPITCG
ESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRIPAGYCFVEFADLATAEKCLHKINGKPLPGATP
AKRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDQTGVSKGYGFVKFTDELEQKRALTECQGAVGLGS
KPVRLSVAIPKASRVKPVEYSQMYSYSYNQYYQQYQNYYAQWGYDQNTGSYSYSYPQYGYTQSTMQTYEEVGDDALEDPMPQLDVTEANK

--------------------------------------------------------------
>33481_33481_6_GMEB1-TRNAU1AP_GMEB1_chr1_29019557_ENST00000373816_TRNAU1AP_chr1_28887145_ENST00000373830_length(transcript)=2220nt_BP=578nt
AAGCCCGGCCTGGCGGCGGCGGTGGCGGTAGCTGCCGTGGCGGCCTCTGCGCATGCTCCGTCGCCTGCCCGCCCTGGCCGCTCGCCGCCC
GCCCGCCCGACGGAGACGCAGTCCCAGCTATCTGACTTCATGTGAAAGATGGCTAATGCAGAAGTGAGTGTCCCAGTGGGGGATGTGGTT
GTGGTACCTACTGAAGGAAATGAAGGGGAGAATCCTGAAGACACTAAAACCCAAGTGATTTTGCAGTTACAGCCTGTGCAACAAGGGATT
TATGAAGCTGGGTCGGAGAACAACACGGCAGTTGTAGCAGTAGAAACTCACACGATACACAAAATTGAAGAAGGGATTGATACAGGCACT
ATAGAAGCAAATGAGGATATGGAAATTGCTTACCCCATAACTTGTGGGGAGAGCAAAGCCATCCTCCTCTGGAAGAAGTTTGTATGTCCA
GGAATAAACGTGAAGTGTGTCAAGTTCAATGATCAGTTGATCAGCCCCAAGCACTTTGTTCATCTGGCTGGCAAGTCCACTCTGAAGGAC
TGGAAGAGAGCTATTCGTCTGGGTGGGATCATGCTCAGGATCCCAGCTGGCTACTGCTTTGTAGAATTTGCAGATTTGGCCACAGCTGAG
AAGTGTTTGCATAAAATTAATGGGAAACCCCTTCCAGGAGCCACACCTGCGAAACGTTTTAAACTGAACTATGCCACTTACGGGAAACAA
CCAGATAACAGCCCTGAGTATTCCCTCTTTGTGGGGGACCTGACCCCGGACGTGGATGATGGCATGCTGTATGAATTCTTCGTCAAAGTC
TACCCCTCCTGTCGGGGAGGCAAGGTGGTTTTGGACCAGACAGGCGTGTCTAAGGGTTATGGTTTTGTGAAATTCACAGATGAACTGGAA
CAGAAGCGAGCCCTGACGGAGTGCCAGGGAGCAGTGGGACTGGGGTCTAAGCCTGTGCGGCTGAGCGTGGCAATCCCTAAAGCGAGCCGT
GTAAAGCCAGTGGAATATAGTCAGATGTACAGTTATAGCTACAACCAGTATTATCAGCAGTACCAGAACTACTATGCTCAGTGGGGCTAT
GACCAGAACACAGGCAGCTACAGCTACAGTTACCCCCAGTATGGCTATACCCAGAGCACCATGCAGACATATGAAGAAGTTGGAGATGAT
GCATTGGAAGACCCCATGCCACAGCTGGATGTGACTGAGGCCAACAAGGAGTTCATGGAACAGAGTGAGGAGCTGTATGACGCTCTGATG
GACTGTCACTGGCAGCCCCTGGACACAGTGTCTTCAGAGATCCCTGCCATGATGTAGCCAGGCCAAAGGACAAGCCAGGTTGCATGATGT
GAGGGAGATGAGAGACTCCTTTTTAAAAATTGTGAAACCTTTTTGGAAATATGATTTGTAAGATTTTAATAATGACTGTTTTTGGAGATC
ATGAATGTTTCTACAACACTGCTGCATTCATTTGACCATTTGAGTTTGAAGACCAAGGGAACAACTTTTAAACAAGGTTCAAATTGGTTT
CCTTCACAGGAATCCTTTGTCCAGGTAGTTATCCACATAGGACAGTTTGGGATTATCCAAAACTGGGATGAGCAGCTTGGGATAATTCAC
ACACTAAAGCCTGAGTTCAAGGTTTCTCAGTTGACAGGTAGGTATGTAAATCAGGGTTCTCTGGAGTATTTGTAGGACCTGCCATATTTG
AGTCCTAACTTGGTGCAAGTCTGGCAGCTAGGTAGAAAAGGCACTCTAGCAGGTGTGGTAGGAGCACGCCCCAGAAGGTAGAATGTGGTG
GGGTGTGATGGAACAGGCCAGTTGGCCTAAGAATTAGTACTTGCTCTAATAATGGGTTTCATCTATTTTCATGAGTTGCAGCATCTGCAT
ATACAAGGCCTGGATCACTTTAGGATCAATATTTTGACACGGGAGAAGGCAGCTCAGAAAGGATTAAGGAAGATAGCTCAAAGCCAAAGC
AGACCCTCCGTGTGAACTTTATACTGCTCACTTCCGTGTTTCCCAAGTAAATGGGGAAACTGTCCAACCTTGTCATGTGTTGGGACTTAC
TGCTTGAGGCAAAGCATTCATCCTACATCATAAAAAATCTCCAAAGATCTCTTTAAGGGCTGGGCATGGTGGCTCACTTTGGGAGATGGA

>33481_33481_6_GMEB1-TRNAU1AP_GMEB1_chr1_29019557_ENST00000373816_TRNAU1AP_chr1_28887145_ENST00000373830_length(amino acids)=392AA_BP=146
MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANEDMEIAYPITCG
ESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRIPAGYCFVEFADLATAEKCLHKINGKPLPGATP
AKRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDQTGVSKGYGFVKFTDELEQKRALTECQGAVGLGS
KPVRLSVAIPKASRVKPVEYSQMYSYSYNQYYQQYQNYYAQWGYDQNTGSYSYSYPQYGYTQSTMQTYEEVGDDALEDPMPQLDVTEANK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for GMEB1-TRNAU1AP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GMEB1-TRNAU1AP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GMEB1-TRNAU1AP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource