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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GNA12-TTYH3 (FusionGDB2 ID:33532)

Fusion Gene Summary for GNA12-TTYH3

check button Fusion gene summary
Fusion gene informationFusion gene name: GNA12-TTYH3
Fusion gene ID: 33532
HgeneTgene
Gene symbol

GNA12

TTYH3

Gene ID

2768

80727

Gene nameG protein subunit alpha 12tweety family member 3
SynonymsNNX3|RMP|gep-
Cytomap

7p22.3-p22.2

7p22.3

Type of geneprotein-codingprotein-coding
Descriptionguanine nucleotide-binding protein subunit alpha-12WUGSC:H_GS165O14.2g alpha-12guanine nucleotide binding protein (G protein) alpha 12protein tweety homolog 3hTTY3tweety homolog 3
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000275364, ENST00000407904, 
ENST00000544127, ENST00000396960, 
ENST00000407653, ENST00000491117, 
ENST00000403167, ENST00000477439, 
ENST00000258796, ENST00000407643, 
Fusion gene scores* DoF score11 X 4 X 7=3082 X 4 X 2=16
# samples 144
** MAII scorelog2(14/308*10)=-1.13750352374993
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/16*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: GNA12 [Title/Abstract] AND TTYH3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGNA12(2834561)-TTYH3(2686486), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTTYH3

GO:0006821

chloride transport

16219661


check buttonFusion gene breakpoints across GNA12 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TTYH3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-D3-A3C3GNA12chr7

2834561

-TTYH3chr7

2686486

+


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Fusion Gene ORF analysis for GNA12-TTYH3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000275364ENST00000403167GNA12chr7

2834561

-TTYH3chr7

2686486

+
5CDS-intronENST00000275364ENST00000477439GNA12chr7

2834561

-TTYH3chr7

2686486

+
5CDS-intronENST00000407904ENST00000403167GNA12chr7

2834561

-TTYH3chr7

2686486

+
5CDS-intronENST00000407904ENST00000477439GNA12chr7

2834561

-TTYH3chr7

2686486

+
5CDS-intronENST00000544127ENST00000403167GNA12chr7

2834561

-TTYH3chr7

2686486

+
5CDS-intronENST00000544127ENST00000477439GNA12chr7

2834561

-TTYH3chr7

2686486

+
In-frameENST00000275364ENST00000258796GNA12chr7

2834561

-TTYH3chr7

2686486

+
In-frameENST00000275364ENST00000407643GNA12chr7

2834561

-TTYH3chr7

2686486

+
In-frameENST00000407904ENST00000258796GNA12chr7

2834561

-TTYH3chr7

2686486

+
In-frameENST00000407904ENST00000407643GNA12chr7

2834561

-TTYH3chr7

2686486

+
In-frameENST00000544127ENST00000258796GNA12chr7

2834561

-TTYH3chr7

2686486

+
In-frameENST00000544127ENST00000407643GNA12chr7

2834561

-TTYH3chr7

2686486

+
intron-3CDSENST00000396960ENST00000258796GNA12chr7

2834561

-TTYH3chr7

2686486

+
intron-3CDSENST00000396960ENST00000407643GNA12chr7

2834561

-TTYH3chr7

2686486

+
intron-3CDSENST00000407653ENST00000258796GNA12chr7

2834561

-TTYH3chr7

2686486

+
intron-3CDSENST00000407653ENST00000407643GNA12chr7

2834561

-TTYH3chr7

2686486

+
intron-3CDSENST00000491117ENST00000258796GNA12chr7

2834561

-TTYH3chr7

2686486

+
intron-3CDSENST00000491117ENST00000407643GNA12chr7

2834561

-TTYH3chr7

2686486

+
intron-intronENST00000396960ENST00000403167GNA12chr7

2834561

-TTYH3chr7

2686486

+
intron-intronENST00000396960ENST00000477439GNA12chr7

2834561

-TTYH3chr7

2686486

+
intron-intronENST00000407653ENST00000403167GNA12chr7

2834561

-TTYH3chr7

2686486

+
intron-intronENST00000407653ENST00000477439GNA12chr7

2834561

-TTYH3chr7

2686486

+
intron-intronENST00000491117ENST00000403167GNA12chr7

2834561

-TTYH3chr7

2686486

+
intron-intronENST00000491117ENST00000477439GNA12chr7

2834561

-TTYH3chr7

2686486

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000275364GNA12chr72834561-ENST00000258796TTYH3chr72686486+52006881632136657
ENST00000275364GNA12chr72834561-ENST00000407643TTYH3chr72686486+51026881632040625
ENST00000544127GNA12chr72834561-ENST00000258796TTYH3chr72686486+4892380231828601
ENST00000544127GNA12chr72834561-ENST00000407643TTYH3chr72686486+4794380231732569
ENST00000407904GNA12chr72834561-ENST00000258796TTYH3chr72686486+51896773292125598
ENST00000407904GNA12chr72834561-ENST00000407643TTYH3chr72686486+50916773292029566

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000275364ENST00000258796GNA12chr72834561-TTYH3chr72686486+0.0136708250.98632914
ENST00000275364ENST00000407643GNA12chr72834561-TTYH3chr72686486+0.0126031290.9873969
ENST00000544127ENST00000258796GNA12chr72834561-TTYH3chr72686486+0.0095601180.9904399
ENST00000544127ENST00000407643GNA12chr72834561-TTYH3chr72686486+0.0110632940.98893666
ENST00000407904ENST00000258796GNA12chr72834561-TTYH3chr72686486+0.0255281850.9744718
ENST00000407904ENST00000407643GNA12chr72834561-TTYH3chr72686486+0.0312886540.9687113

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Fusion Genomic Features for GNA12-TTYH3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
GNA12chr72834561-TTYH3chr72686486+4.24E-070.9999995
GNA12chr72834561-TTYH3chr72686486+4.24E-070.9999995

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for GNA12-TTYH3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:2834561/chr7:2686486)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGNA12chr7:2834561chr7:2686486ENST00000275364-2467_72175382.0Nucleotide bindingGTP
HgeneGNA12chr7:2834561chr7:2686486ENST00000275364-2459_72175382.0RegionG1 motif
TgeneTTYH3chr7:2834561chr7:2686486ENST00000258796014108_21141524.0Topological domainExtracellular
TgeneTTYH3chr7:2834561chr7:2686486ENST00000258796014233_23641524.0Topological domainCytoplasmic
TgeneTTYH3chr7:2834561chr7:2686486ENST00000258796014258_38641524.0Topological domainExtracellular
TgeneTTYH3chr7:2834561chr7:2686486ENST00000258796014408_52341524.0Topological domainCytoplasmic
TgeneTTYH3chr7:2834561chr7:2686486ENST0000025879601464_8641524.0Topological domainCytoplasmic
TgeneTTYH3chr7:2834561chr7:2686486ENST00000403167010108_2110353.0Topological domainExtracellular
TgeneTTYH3chr7:2834561chr7:2686486ENST000004031670101_420353.0Topological domainExtracellular
TgeneTTYH3chr7:2834561chr7:2686486ENST00000403167010233_2360353.0Topological domainCytoplasmic
TgeneTTYH3chr7:2834561chr7:2686486ENST00000403167010258_3860353.0Topological domainExtracellular
TgeneTTYH3chr7:2834561chr7:2686486ENST00000403167010408_5230353.0Topological domainCytoplasmic
TgeneTTYH3chr7:2834561chr7:2686486ENST0000040316701064_860353.0Topological domainCytoplasmic
TgeneTTYH3chr7:2834561chr7:2686486ENST00000407643013108_21141492.0Topological domainExtracellular
TgeneTTYH3chr7:2834561chr7:2686486ENST00000407643013233_23641492.0Topological domainCytoplasmic
TgeneTTYH3chr7:2834561chr7:2686486ENST00000407643013258_38641492.0Topological domainExtracellular
TgeneTTYH3chr7:2834561chr7:2686486ENST00000407643013408_52341492.0Topological domainCytoplasmic
TgeneTTYH3chr7:2834561chr7:2686486ENST0000040764301364_8641492.0Topological domainCytoplasmic
TgeneTTYH3chr7:2834561chr7:2686486ENST00000258796014212_23241524.0TransmembraneHelical%3B Name%3D3
TgeneTTYH3chr7:2834561chr7:2686486ENST00000258796014237_25741524.0TransmembraneHelical%3B Name%3D4
TgeneTTYH3chr7:2834561chr7:2686486ENST00000258796014387_40741524.0TransmembraneHelical%3B Name%3D5
TgeneTTYH3chr7:2834561chr7:2686486ENST0000025879601443_6341524.0TransmembraneHelical%3B Name%3D1
TgeneTTYH3chr7:2834561chr7:2686486ENST0000025879601487_10741524.0TransmembraneHelical%3B Name%3D2
TgeneTTYH3chr7:2834561chr7:2686486ENST00000403167010212_2320353.0TransmembraneHelical%3B Name%3D3
TgeneTTYH3chr7:2834561chr7:2686486ENST00000403167010237_2570353.0TransmembraneHelical%3B Name%3D4
TgeneTTYH3chr7:2834561chr7:2686486ENST00000403167010387_4070353.0TransmembraneHelical%3B Name%3D5
TgeneTTYH3chr7:2834561chr7:2686486ENST0000040316701043_630353.0TransmembraneHelical%3B Name%3D1
TgeneTTYH3chr7:2834561chr7:2686486ENST0000040316701087_1070353.0TransmembraneHelical%3B Name%3D2
TgeneTTYH3chr7:2834561chr7:2686486ENST00000407643013212_23241492.0TransmembraneHelical%3B Name%3D3
TgeneTTYH3chr7:2834561chr7:2686486ENST00000407643013237_25741492.0TransmembraneHelical%3B Name%3D4
TgeneTTYH3chr7:2834561chr7:2686486ENST00000407643013387_40741492.0TransmembraneHelical%3B Name%3D5
TgeneTTYH3chr7:2834561chr7:2686486ENST0000040764301343_6341492.0TransmembraneHelical%3B Name%3D1
TgeneTTYH3chr7:2834561chr7:2686486ENST0000040764301387_10741492.0TransmembraneHelical%3B Name%3D2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGNA12chr7:2834561chr7:2686486ENST00000275364-2456_381175382.0DomainG-alpha
HgeneGNA12chr7:2834561chr7:2686486ENST00000275364-24202_205175382.0Nucleotide bindingGTP
HgeneGNA12chr7:2834561chr7:2686486ENST00000275364-24296_299175382.0Nucleotide bindingGTP
HgeneGNA12chr7:2834561chr7:2686486ENST00000275364-24200_208175382.0RegionG2 motif
HgeneGNA12chr7:2834561chr7:2686486ENST00000275364-24223_232175382.0RegionG3 motif
HgeneGNA12chr7:2834561chr7:2686486ENST00000275364-24292_299175382.0RegionG4 motif
HgeneGNA12chr7:2834561chr7:2686486ENST00000275364-24351_356175382.0RegionG5 motif
TgeneTTYH3chr7:2834561chr7:2686486ENST000002587960141_4241524.0Topological domainExtracellular
TgeneTTYH3chr7:2834561chr7:2686486ENST000004076430131_4241492.0Topological domainExtracellular


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Fusion Gene Sequence for GNA12-TTYH3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>33532_33532_1_GNA12-TTYH3_GNA12_chr7_2834561_ENST00000275364_TTYH3_chr7_2686486_ENST00000258796_length(transcript)=5200nt_BP=688nt
GGCGACGAGTGCGGGCCTCGGAGCGACTGCAGCGGCGGCGGCGGACGCGGCCTGAGGCGAGCGGCGGGGCGTGGGGCGGTGCCTCGGCCC
GGGCTCGCCCTCGCCGGCGGGAGCGTCCATGGCCCCCGGGCGCCGGCGGGGCGCGGCCGCGGCCTGAGGGGCCATGTCCGGGGTGGTGCG
GACCCTCAGCCGCTGCCTGCTGCCGGCCGAGGCCGGCGGGGCCCGCGAGCGCAGGGCGGGCAGCGGCGCGCGCGACGCGGAGCGCGAGGC
CCGGAGGCGTAGCCGCGACATCGACGCGCTGCTGGCCCGCGAGCGGCGCGCGGTCCGGCGCCTGGTGAAGATCCTGCTGCTGGGCGCGGG
CGAGAGCGGCAAGTCCACGTTCCTCAAGCAGATGCGCATCATCCACGGCCGCGAGTTCGACCAGAAGGCGCTGCTGGAGTTCCGCGACAC
CATCTTCGACAACATCCTCAAGGGCTCAAGGGTTCTTGTTGATGCACGAGATAAGCTTGGCATTCCTTGGCAGTATTCTGAAAATGAGAA
GCATGGGATGTTCCTGATGGCCTTCGAGAACAAGGCGGGGCTGCCTGTGGAGCCGGCCACCTTCCAGCTGTACGTCCCGGCCCTGAGCGC
ACTCTGGAGGGATTCTGGCATCAGGGAGGCTTTCAGCCGGAGAAGCGAGTTTCAGCTGGCCCTGCTGCTCCTGGGGGCCGCCGCCCTGGC
CTGCCTCGCCCTGGACCTCCTCTTCCTGCTCTTCTACTCCTTCTGGCTGTGCTGCCGGCGGCGCAAGAGCGAGGAGCACCTGGACGCCGA
CTGCTGCTGCACGGCCTGGTGTGTCATCATCGCCACGCTGGTGTGCAGCGCCGGCATCGCAGTGGGATTCTACGGCAACGGGGAGACCAG
TGATGGCATCCATAGGGCCACCTACTCGCTCCGCCACGCCAACCGCACGGTGGCCGGGGTCCAGGACCGCGTGTGGGACACGGCGGTGGG
GCTGAACCACACGGCGGAGCCCAGCCTGCAGACCCTGGAGCGGCAGCTGGCCGGGCGGCCCGAGCCCCTGCGAGCCGTACAGAGGCTGCA
GGGCCTGCTGGAGACGCTGCTGGGCTACACGGCCGCCATCCCCTTTTGGAGGAACACGGCGGTGTCGCTGGAGGTGCTGGCGGAGCAGGT
GGATCTCTACGACTGGTACAGGTGGCTGGGCTACCTGGGCCTGCTGCTGCTGGACGTCATCATCTGCCTCCTGGTGCTGGTTGGCCTCAT
CCGCAGCTCCAAGGGCATCCTGGTGGGGGTCTGCCTGCTGGGAGTCCTGGCCCTGGTCATCAGCTGGGGCGCGCTGGGCTTGGAGCTGGC
TGTGTCCGTGGGCTCCAGCGACTTCTGTGTGGACCCTGACGCCTACGTGACCAAAATGGTGGAGGAGTACTCGGTGCTGAGTGGGGACAT
CCTGCAGTACTACCTGGCCTGCTCGCCCCGCGCCGCCAACCCCTTCCAGCAGAAGCTGTCGGGCAGCCACAAGGCACTGGTGGAGATGCA
GGATGTCGTGGCTGAGCTTCTGAGGACCGTCCCCTGGGAGCAGCCGGCCACTAAGGACCCCCTCCTCCGCGTCCAGGAGGTGCTGAATGG
CACGGAGGTGAACCTGCAGCACCTCACCGCCCTGGTGGACTGCCGCAGCCTGCATCTGGACTACGTGCAAGCGCTGACCGGCTTCTGCTA
TGACGGCGTGGAGGGCCTCATCTACCTGGCCCTCTTCTCCTTCGTCACAGCCCTCATGTTCAGCTCCATCGTCTGCAGCGTCCCGCACAC
CTGGCAGCAAAAGAGAGGCCCTGATGAGGACGGGGAGGAGGAGGCCGCTCCAGGGCCGCGGCAGGCGCACGACAGCCTCTACCGCGTCCA
CATGCCCAGCCTGTACAGCTGTGGCAGCAGCTACGGCAGTGAGACCAGCATCCCGGCCGCGGCCCACACCGTCAGCAACGCCCCGGTCAC
TGAGTACATGAGCCAGAACGCTAATTTCCAGAACCCCCGCTGTGAGAACACCCCACTCATTGGGCGCGAGTCCCCGCCGCCCTCATACAC
CTCCAGCATGAGAGCCAAATACCTCGCCACGAGCCAGCCTCGCCCTGACTCCAGCGGCAGCCACTAGACCGCGCCCGGCAGCCACCCACC
CCACGTGCCAACTTCCCCTCCCCGTGCCAGCACTGCCGCTTCCACCTGGGCCACCCACCGGACCCTCGCACGCCGTGCCAGGCCTGCCCC
AGACGCGTCTGCAGGCCGCTTGCCCTCCTGTCCCCTCCCCGCAGGGGCACAGTGGAGACGCAGGGGCTCTGGGCCCGTACCGCCAACTCG
GGTCACACCTGAACGCTGCTGCCAGCCGATGCCCCAGCCCTGCACGCCACCCACTATCCCGGCACGCTCCCTCTGCAGATGGTCGCCGCA
CCTACAAGCCCTGGCCGCACCCAACCTGTGTTGTTGCCGCCCGGCCCTTCCCTCCACAGCTCTCCTTCCTCCCGCCCGGCACTTCTGTGG
ACCCCTTCTTAGTTCACAGGCACGGCTGGGGCCGCTCTGTGCTGGCGCCTGCTGGCCACTGAGGGACAGGGACACGTGCCACCTGCTCAT
CTCTGCCCTGAGGTCACCCCGTGGTCCCTCCACGTGCCCATCTCTCTGCAGTGCCCTCCTCGCCTGTGCAGCCCGCCCACCCACAGGCTC
ACCCCTCCTGCCGGCTGCCAGAGGCCCCCTCCAGCAGGGCCTCTCTCCGTTGCCCCAGCTTCACTCTCTCCCTCAGCACCTGCCCTGCTG
GAGGCCCCAGCCCTCCGTGGACAGCAGGGGCCACGTGGAGCCCGGGCCGCTCACCCGCCACCCAGTGCTGGCCGCCTTCTTGGTGCCAAA
CCCCCTTCCCCCACCCAGAGACTGGGCAGCTGTGTCTGGTTCGTTCTTTGCACTAACCACATTTGTCATCTCTAGGGCAGGCTGGGGCTG
CGGGCTGAGGGGGACCGCTGGCACCCCCCTTCCCTCCCTTCTTGGTTCCATTTCCATCCATGACAGGTACAGCATCCCAGGAGCCCGGCC
TGAGGGGCTGGACCCGAGCCGGCTGTGAACATCCCTCAGCCCCTGCTGTCCCCCCTTGGGACTAACCACTAACCTCACCCCCAAACTCCA
CGGGTGCCCCTAGCTGGCCCAGAGCCGGCAGTGTGAGCCCAAGTCCGGGCTGGAGCCGAGGCCGGAGCAGCTGTCTGGGAGTCAAGGCTG
CAGTAGCGTTTCTTCATGGGGTGCTCCAGGGGGTGCCACAGACCGACAGGCAGCCCAAGGGCCTGGACACCCCTCCCCAGGCAGGTGCTG
CCCCAGGAGGACTGTCCTCGGGAATGAACCTCCCGCGGGCTTTGGACTGAGGTCCCTGTGGCCTCGGTCTCCTCCCCATGAAGTGGGAGC
GAGGCTCCCCAATGGTGCTTTTGGCTTTAGTGTACGATGTTTGCTGTGCTTCCCGCCGTGGAGGGCAGAGCCACCCCACATCAGGATCGG
ACGTGCTACCCCTCCCGGTCCCGGCCCTGGCCCAGCCAGCCCAGCCCTCGAGGCTCGATGCCTGTGCCAAGGCCAGGGGCAGCCAGAGGG
CAGCTGGATGGCCACGTGCAGGGGTCAAGGCTGGGCCCTGCAGTGGGGCGGGCCGCCAGCCCCAGCAGTTTACAGACGCATGGCTCTTCC
TCCCAGAGCAGCCGGCAGCTACCTGGACCGGAAATGTCCTCATCCCCTCCCTGGGGCCAGGCTCTGCCCTGGCCTTCCTCTGTGAACCCC
TCCTTTCTTTGTGCTGGTGTCTGGGACCAAAAAGGGGGAATATGGGAGGGCAGAGTGGGGAGGGGAGTCCATGGGCCTGGGGCCCCAAGC
CGGGGCGTCTGAGCTCCCCAGGCATGACCAAACCTCAGTGGAGGGGCCTCTGCTTCAGGCCCCGCCTGGCTGACATTCTGAGCCCCCCTC
GGAGGCCCCGCCACAGCCAACCTGCCCAGTCTTTCCTCTGGGCTTGACCCGCCAGGGGAGTTCTCCAGGCCTAGGGCCAGGAGAGAGGCC
CTGGCACCCTGGCGTGGGTGCCCGCCAAACGCCCTGCGACCGCTCAGAAGCACAAATGCTGTCCATGGCCGTGAGGCTGCCTGCCAGGTG
AATGGACATAGCGTGAGAGGCGGTGAGGCCAGGGCTTCCAGCCTCGTGCTGTCTCGGGACTCCTGACCGTGGTGTGCGTGTGTGCCCGTC
TGTGACTTTCTACTCACCAAGGTTGAAGAAAGGAAACGGGGAAAATCAAAAGGGGTTCAAACCCCACCTCAGTAGGTGGAGGGGAGCGCC
TGCCATTGGTTGTATTTTTGTTCTGAGTTTTCGGTGCCGTGTTCCTAACTACTCCATCCCATGACCTCGCCACACCTACTGGGGCATCTG
GCTGGTGCCTGCTGCCATGGCCAGCCCCCACTCTCACCCTGCACAGGGGGTCTTGCAGCCCCCAGGCCCACAGCCTCGTTGGGAGGACAG
GGTGGCCCTGGGGACAAGAGGGAGGAGCCCAGGGGCTTACCTCACTGAGAGTGCTCCCCAGCAGGCATCCACTACCCCAGGGCCCCCCAC
ATGTCATGGCAAGGTTGGTAGTGAATGGGCCTGGTTGGGAGCAGCCCCTGGCCCATTGCCCACCCACCCATCTCACTATGCAATTCGAGT
TCCAAGCAACATTTGCTCCTGCCCTGGGGCCAGCTCTGCCCCAGCCCTGAGAGGGGTGGTGAGGCAGCCCCCTGGACCCCAGAACCCCAG
ACAAGGGGGCAGGCGGGGGACCAGGGCCTCTCCTGTGGGATCTTTGTTTTGTGTTTAACCATAATGGTTGTGTACTGAACCACTTCATAT
TTGTTATATATAATATATATATATATAATCTCCTTAAGACTCAGCCTCCTGGTTTACCCCCCCGGCCTGGGCATCTGACCTCCCCCACCC
CAGTGTGATTTAACATCCAGGAACTGAGGCCTGAACCATTTTGCATTTCCCCCTCCTCCAGCCTCTGTAGGGCCATGGCTGTATGTACTG
TCGCTGTGTTTTTTTGTTTTTTTAGAACTGGGTTTGGGGGCTGATTTTTATTTCTTTGGGGGCTTTTTTTCTTGGCAAATACTAAAAATC

>33532_33532_1_GNA12-TTYH3_GNA12_chr7_2834561_ENST00000275364_TTYH3_chr7_2686486_ENST00000258796_length(amino acids)=657AA_BP=0
MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKAL
LEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLALLLL
GAAALACLALDLLFLLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGIHRATYSLRHANRTVAGVQDRV
WDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLGYTAAIPFWRNTAVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLL
VLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMVEEYSVLSGDILQYYLACSPRAANPFQQKLSGSHK
ALVEMQDVVAELLRTVPWEQPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIV
CSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSETSIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRES

--------------------------------------------------------------
>33532_33532_2_GNA12-TTYH3_GNA12_chr7_2834561_ENST00000275364_TTYH3_chr7_2686486_ENST00000407643_length(transcript)=5102nt_BP=688nt
GGCGACGAGTGCGGGCCTCGGAGCGACTGCAGCGGCGGCGGCGGACGCGGCCTGAGGCGAGCGGCGGGGCGTGGGGCGGTGCCTCGGCCC
GGGCTCGCCCTCGCCGGCGGGAGCGTCCATGGCCCCCGGGCGCCGGCGGGGCGCGGCCGCGGCCTGAGGGGCCATGTCCGGGGTGGTGCG
GACCCTCAGCCGCTGCCTGCTGCCGGCCGAGGCCGGCGGGGCCCGCGAGCGCAGGGCGGGCAGCGGCGCGCGCGACGCGGAGCGCGAGGC
CCGGAGGCGTAGCCGCGACATCGACGCGCTGCTGGCCCGCGAGCGGCGCGCGGTCCGGCGCCTGGTGAAGATCCTGCTGCTGGGCGCGGG
CGAGAGCGGCAAGTCCACGTTCCTCAAGCAGATGCGCATCATCCACGGCCGCGAGTTCGACCAGAAGGCGCTGCTGGAGTTCCGCGACAC
CATCTTCGACAACATCCTCAAGGGCTCAAGGGTTCTTGTTGATGCACGAGATAAGCTTGGCATTCCTTGGCAGTATTCTGAAAATGAGAA
GCATGGGATGTTCCTGATGGCCTTCGAGAACAAGGCGGGGCTGCCTGTGGAGCCGGCCACCTTCCAGCTGTACGTCCCGGCCCTGAGCGC
ACTCTGGAGGGATTCTGGCATCAGGGAGGCTTTCAGCCGGAGAAGCGAGTTTCAGCTGGCCCTGCTGCTCCTGGGGGCCGCCGCCCTGGC
CTGCCTCGCCCTGGACCTCCTCTTCCTGCTCTTCTACTCCTTCTGGCTGTGCTGCCGGCGGCGCAAGAGCGAGGAGCACCTGGACGCCGA
CTGCTGCTGCACGGCCTGGTGTGTCATCATCGCCACGCTGGTGTGCAGCGCCGGCATCGCAGTGGGATTCTACGGCAACGGGGAGACCAG
TGATGGCATCCATAGGGCCACCTACTCGCTCCGCCACGCCAACCGCACGGTGGCCGGGGTCCAGGACCGCGTGTGGGACACGGCGGTGGG
GCTGAACCACACGGCGGAGCCCAGCCTGCAGACCCTGGAGCGGCAGCTGGCCGGGCGGCCCGAGCCCCTGCGAGCCGTACAGAGGCTGCA
GGGCCTGCTGGAGACGCTGCTGGGCTACACGGCCGCCATCCCCTTTTGGAGGAACACGGCGGTGTCGCTGGAGGTGCTGGCGGAGCAGGT
GGATCTCTACGACTGGTACAGGGTCTGCCTGCTGGGAGTCCTGGCCCTGGTCATCAGCTGGGGCGCGCTGGGCTTGGAGCTGGCTGTGTC
CGTGGGCTCCAGCGACTTCTGTGTGGACCCTGACGCCTACGTGACCAAAATGGTGGAGGAGTACTCGGTGCTGAGTGGGGACATCCTGCA
GTACTACCTGGCCTGCTCGCCCCGCGCCGCCAACCCCTTCCAGCAGAAGCTGTCGGGCAGCCACAAGGCACTGGTGGAGATGCAGGATGT
CGTGGCTGAGCTTCTGAGGACCGTCCCCTGGGAGCAGCCGGCCACTAAGGACCCCCTCCTCCGCGTCCAGGAGGTGCTGAATGGCACGGA
GGTGAACCTGCAGCACCTCACCGCCCTGGTGGACTGCCGCAGCCTGCATCTGGACTACGTGCAAGCGCTGACCGGCTTCTGCTATGACGG
CGTGGAGGGCCTCATCTACCTGGCCCTCTTCTCCTTCGTCACAGCCCTCATGTTCAGCTCCATCGTCTGCAGCGTCCCGCACACCTGGCA
GCAAAAGAGAGGCCCTGATGAGGACGGGGAGGAGGAGGCCGCTCCAGGGCCGCGGCAGGCGCACGACAGCCTCTACCGCGTCCACATGCC
CAGCCTGTACAGCTGTGGCAGCAGCTACGGCAGTGAGACCAGCATCCCGGCCGCGGCCCACACCGTCAGCAACGCCCCGGTCACTGAGTA
CATGAGCCAGAACGCTAATTTCCAGAACCCCCGCTGTGAGAACACCCCACTCATTGGGCGCGAGTCCCCGCCGCCCTCATACACCTCCAG
CATGAGAGCCAAATACCTCGCCACGAGCCAGCCTCGCCCTGACTCCAGCGGCAGCCACTAGACCGCGCCCGGCAGCCACCCACCCCACGT
GCCAACTTCCCCTCCCCGTGCCAGCACTGCCGCTTCCACCTGGGCCACCCACCGGACCCTCGCACGCCGTGCCAGGCCTGCCCCAGACGC
GTCTGCAGGCCGCTTGCCCTCCTGTCCCCTCCCCGCAGGGGCACAGTGGAGACGCAGGGGCTCTGGGCCCGTACCGCCAACTCGGGTCAC
ACCTGAACGCTGCTGCCAGCCGATGCCCCAGCCCTGCACGCCACCCACTATCCCGGCACGCTCCCTCTGCAGATGGTCGCCGCACCTACA
AGCCCTGGCCGCACCCAACCTGTGTTGTTGCCGCCCGGCCCTTCCCTCCACAGCTCTCCTTCCTCCCGCCCGGCACTTCTGTGGACCCCT
TCTTAGTTCACAGGCACGGCTGGGGCCGCTCTGTGCTGGCGCCTGCTGGCCACTGAGGGACAGGGACACGTGCCACCTGCTCATCTCTGC
CCTGAGGTCACCCCGTGGTCCCTCCACGTGCCCATCTCTCTGCAGTGCCCTCCTCGCCTGTGCAGCCCGCCCACCCACAGGCTCACCCCT
CCTGCCGGCTGCCAGAGGCCCCCTCCAGCAGGGCCTCTCTCCGTTGCCCCAGCTTCACTCTCTCCCTCAGCACCTGCCCTGCTGGAGGCC
CCAGCCCTCCGTGGACAGCAGGGGCCACGTGGAGCCCGGGCCGCTCACCCGCCACCCAGTGCTGGCCGCCTTCTTGGTGCCAAACCCCCT
TCCCCCACCCAGAGACTGGGCAGCTGTGTCTGGTTCGTTCTTTGCACTAACCACATTTGTCATCTCTAGGGCAGGCTGGGGCTGCGGGCT
GAGGGGGACCGCTGGCACCCCCCTTCCCTCCCTTCTTGGTTCCATTTCCATCCATGACAGGTACAGCATCCCAGGAGCCCGGCCTGAGGG
GCTGGACCCGAGCCGGCTGTGAACATCCCTCAGCCCCTGCTGTCCCCCCTTGGGACTAACCACTAACCTCACCCCCAAACTCCACGGGTG
CCCCTAGCTGGCCCAGAGCCGGCAGTGTGAGCCCAAGTCCGGGCTGGAGCCGAGGCCGGAGCAGCTGTCTGGGAGTCAAGGCTGCAGTAG
CGTTTCTTCATGGGGTGCTCCAGGGGGTGCCACAGACCGACAGGCAGCCCAAGGGCCTGGACACCCCTCCCCAGGCAGGTGCTGCCCCAG
GAGGACTGTCCTCGGGAATGAACCTCCCGCGGGCTTTGGACTGAGGTCCCTGTGGCCTCGGTCTCCTCCCCATGAAGTGGGAGCGAGGCT
CCCCAATGGTGCTTTTGGCTTTAGTGTACGATGTTTGCTGTGCTTCCCGCCGTGGAGGGCAGAGCCACCCCACATCAGGATCGGACGTGC
TACCCCTCCCGGTCCCGGCCCTGGCCCAGCCAGCCCAGCCCTCGAGGCTCGATGCCTGTGCCAAGGCCAGGGGCAGCCAGAGGGCAGCTG
GATGGCCACGTGCAGGGGTCAAGGCTGGGCCCTGCAGTGGGGCGGGCCGCCAGCCCCAGCAGTTTACAGACGCATGGCTCTTCCTCCCAG
AGCAGCCGGCAGCTACCTGGACCGGAAATGTCCTCATCCCCTCCCTGGGGCCAGGCTCTGCCCTGGCCTTCCTCTGTGAACCCCTCCTTT
CTTTGTGCTGGTGTCTGGGACCAAAAAGGGGGAATATGGGAGGGCAGAGTGGGGAGGGGAGTCCATGGGCCTGGGGCCCCAAGCCGGGGC
GTCTGAGCTCCCCAGGCATGACCAAACCTCAGTGGAGGGGCCTCTGCTTCAGGCCCCGCCTGGCTGACATTCTGAGCCCCCCTCGGAGGC
CCCGCCACAGCCAACCTGCCCAGTCTTTCCTCTGGGCTTGACCCGCCAGGGGAGTTCTCCAGGCCTAGGGCCAGGAGAGAGGCCCTGGCA
CCCTGGCGTGGGTGCCCGCCAAACGCCCTGCGACCGCTCAGAAGCACAAATGCTGTCCATGGCCGTGAGGCTGCCTGCCAGGTGAATGGA
CATAGCGTGAGAGGCGGTGAGGCCAGGGCTTCCAGCCTCGTGCTGTCTCGGGACTCCTGACCGTGGTGTGCGTGTGTGCCCGTCTGTGAC
TTTCTACTCACCAAGGTTGAAGAAAGGAAACGGGGAAAATCAAAAGGGGTTCAAACCCCACCTCAGTAGGTGGAGGGGAGCGCCTGCCAT
TGGTTGTATTTTTGTTCTGAGTTTTCGGTGCCGTGTTCCTAACTACTCCATCCCATGACCTCGCCACACCTACTGGGGCATCTGGCTGGT
GCCTGCTGCCATGGCCAGCCCCCACTCTCACCCTGCACAGGGGGTCTTGCAGCCCCCAGGCCCACAGCCTCGTTGGGAGGACAGGGTGGC
CCTGGGGACAAGAGGGAGGAGCCCAGGGGCTTACCTCACTGAGAGTGCTCCCCAGCAGGCATCCACTACCCCAGGGCCCCCCACATGTCA
TGGCAAGGTTGGTAGTGAATGGGCCTGGTTGGGAGCAGCCCCTGGCCCATTGCCCACCCACCCATCTCACTATGCAATTCGAGTTCCAAG
CAACATTTGCTCCTGCCCTGGGGCCAGCTCTGCCCCAGCCCTGAGAGGGGTGGTGAGGCAGCCCCCTGGACCCCAGAACCCCAGACAAGG
GGGCAGGCGGGGGACCAGGGCCTCTCCTGTGGGATCTTTGTTTTGTGTTTAACCATAATGGTTGTGTACTGAACCACTTCATATTTGTTA
TATATAATATATATATATATAATCTCCTTAAGACTCAGCCTCCTGGTTTACCCCCCCGGCCTGGGCATCTGACCTCCCCCACCCCAGTGT
GATTTAACATCCAGGAACTGAGGCCTGAACCATTTTGCATTTCCCCCTCCTCCAGCCTCTGTAGGGCCATGGCTGTATGTACTGTCGCTG
TGTTTTTTTGTTTTTTTAGAACTGGGTTTGGGGGCTGATTTTTATTTCTTTGGGGGCTTTTTTTCTTGGCAAATACTAAAAATCTCGTCA

>33532_33532_2_GNA12-TTYH3_GNA12_chr7_2834561_ENST00000275364_TTYH3_chr7_2686486_ENST00000407643_length(amino acids)=625AA_BP=0
MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKAL
LEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLALLLL
GAAALACLALDLLFLLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGIHRATYSLRHANRTVAGVQDRV
WDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLGYTAAIPFWRNTAVSLEVLAEQVDLYDWYRVCLLGVLALVISWGALG
LELAVSVGSSDFCVDPDAYVTKMVEEYSVLSGDILQYYLACSPRAANPFQQKLSGSHKALVEMQDVVAELLRTVPWEQPATKDPLLRVQE
VLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSL

--------------------------------------------------------------
>33532_33532_3_GNA12-TTYH3_GNA12_chr7_2834561_ENST00000407904_TTYH3_chr7_2686486_ENST00000258796_length(transcript)=5189nt_BP=677nt
ATTTAAGCAGCCTCCTTGACTGTAGGTCCGCTGACTGGCTTCCTCCTTGAGAGCACACTCACAGTGCCGGACCGCAGGCACCTCGCCGAT
GTTCCTGTCCACTTGCTTTTTGTATTGCTCCTTCTCCAGTGAGCTTGGAAGCCTCATGCGGGCAAGGCCTTGTCTGTCTGGTTCTCTGTT
GTGTCCTCGGAGCCTGCCACAGTGGCGGCGCTTGGTGGCTTTGACAGGGGACTGGATTGGGTGGAAGGGGCGAGATTAGACCTGGATACA
GTGACGTCCTTGTCAGCCATGCCGAGTGCAGAGCGCCTACTGTATTGTAGGCATTTGAAATGAAACGGAGAATGTTTCCCAGGCCGTGCC
TAGCAAGGATGCCTGGCAGTCGTGGTTCGGGAAGCACACCAGATGGAAACCGAAAGTGCTGCCGTTTTGAGCACCTACTCATTGCACACC
CTGGGTCCAGGGGCTCAAGGGTTCTTGTTGATGCACGAGATAAGCTTGGCATTCCTTGGCAGTATTCTGAAAATGAGAAGCATGGGATGT
TCCTGATGGCCTTCGAGAACAAGGCGGGGCTGCCTGTGGAGCCGGCCACCTTCCAGCTGTACGTCCCGGCCCTGAGCGCACTCTGGAGGG
ATTCTGGCATCAGGGAGGCTTTCAGCCGGAGAAGCGAGTTTCAGCTGGCCCTGCTGCTCCTGGGGGCCGCCGCCCTGGCCTGCCTCGCCC
TGGACCTCCTCTTCCTGCTCTTCTACTCCTTCTGGCTGTGCTGCCGGCGGCGCAAGAGCGAGGAGCACCTGGACGCCGACTGCTGCTGCA
CGGCCTGGTGTGTCATCATCGCCACGCTGGTGTGCAGCGCCGGCATCGCAGTGGGATTCTACGGCAACGGGGAGACCAGTGATGGCATCC
ATAGGGCCACCTACTCGCTCCGCCACGCCAACCGCACGGTGGCCGGGGTCCAGGACCGCGTGTGGGACACGGCGGTGGGGCTGAACCACA
CGGCGGAGCCCAGCCTGCAGACCCTGGAGCGGCAGCTGGCCGGGCGGCCCGAGCCCCTGCGAGCCGTACAGAGGCTGCAGGGCCTGCTGG
AGACGCTGCTGGGCTACACGGCCGCCATCCCCTTTTGGAGGAACACGGCGGTGTCGCTGGAGGTGCTGGCGGAGCAGGTGGATCTCTACG
ACTGGTACAGGTGGCTGGGCTACCTGGGCCTGCTGCTGCTGGACGTCATCATCTGCCTCCTGGTGCTGGTTGGCCTCATCCGCAGCTCCA
AGGGCATCCTGGTGGGGGTCTGCCTGCTGGGAGTCCTGGCCCTGGTCATCAGCTGGGGCGCGCTGGGCTTGGAGCTGGCTGTGTCCGTGG
GCTCCAGCGACTTCTGTGTGGACCCTGACGCCTACGTGACCAAAATGGTGGAGGAGTACTCGGTGCTGAGTGGGGACATCCTGCAGTACT
ACCTGGCCTGCTCGCCCCGCGCCGCCAACCCCTTCCAGCAGAAGCTGTCGGGCAGCCACAAGGCACTGGTGGAGATGCAGGATGTCGTGG
CTGAGCTTCTGAGGACCGTCCCCTGGGAGCAGCCGGCCACTAAGGACCCCCTCCTCCGCGTCCAGGAGGTGCTGAATGGCACGGAGGTGA
ACCTGCAGCACCTCACCGCCCTGGTGGACTGCCGCAGCCTGCATCTGGACTACGTGCAAGCGCTGACCGGCTTCTGCTATGACGGCGTGG
AGGGCCTCATCTACCTGGCCCTCTTCTCCTTCGTCACAGCCCTCATGTTCAGCTCCATCGTCTGCAGCGTCCCGCACACCTGGCAGCAAA
AGAGAGGCCCTGATGAGGACGGGGAGGAGGAGGCCGCTCCAGGGCCGCGGCAGGCGCACGACAGCCTCTACCGCGTCCACATGCCCAGCC
TGTACAGCTGTGGCAGCAGCTACGGCAGTGAGACCAGCATCCCGGCCGCGGCCCACACCGTCAGCAACGCCCCGGTCACTGAGTACATGA
GCCAGAACGCTAATTTCCAGAACCCCCGCTGTGAGAACACCCCACTCATTGGGCGCGAGTCCCCGCCGCCCTCATACACCTCCAGCATGA
GAGCCAAATACCTCGCCACGAGCCAGCCTCGCCCTGACTCCAGCGGCAGCCACTAGACCGCGCCCGGCAGCCACCCACCCCACGTGCCAA
CTTCCCCTCCCCGTGCCAGCACTGCCGCTTCCACCTGGGCCACCCACCGGACCCTCGCACGCCGTGCCAGGCCTGCCCCAGACGCGTCTG
CAGGCCGCTTGCCCTCCTGTCCCCTCCCCGCAGGGGCACAGTGGAGACGCAGGGGCTCTGGGCCCGTACCGCCAACTCGGGTCACACCTG
AACGCTGCTGCCAGCCGATGCCCCAGCCCTGCACGCCACCCACTATCCCGGCACGCTCCCTCTGCAGATGGTCGCCGCACCTACAAGCCC
TGGCCGCACCCAACCTGTGTTGTTGCCGCCCGGCCCTTCCCTCCACAGCTCTCCTTCCTCCCGCCCGGCACTTCTGTGGACCCCTTCTTA
GTTCACAGGCACGGCTGGGGCCGCTCTGTGCTGGCGCCTGCTGGCCACTGAGGGACAGGGACACGTGCCACCTGCTCATCTCTGCCCTGA
GGTCACCCCGTGGTCCCTCCACGTGCCCATCTCTCTGCAGTGCCCTCCTCGCCTGTGCAGCCCGCCCACCCACAGGCTCACCCCTCCTGC
CGGCTGCCAGAGGCCCCCTCCAGCAGGGCCTCTCTCCGTTGCCCCAGCTTCACTCTCTCCCTCAGCACCTGCCCTGCTGGAGGCCCCAGC
CCTCCGTGGACAGCAGGGGCCACGTGGAGCCCGGGCCGCTCACCCGCCACCCAGTGCTGGCCGCCTTCTTGGTGCCAAACCCCCTTCCCC
CACCCAGAGACTGGGCAGCTGTGTCTGGTTCGTTCTTTGCACTAACCACATTTGTCATCTCTAGGGCAGGCTGGGGCTGCGGGCTGAGGG
GGACCGCTGGCACCCCCCTTCCCTCCCTTCTTGGTTCCATTTCCATCCATGACAGGTACAGCATCCCAGGAGCCCGGCCTGAGGGGCTGG
ACCCGAGCCGGCTGTGAACATCCCTCAGCCCCTGCTGTCCCCCCTTGGGACTAACCACTAACCTCACCCCCAAACTCCACGGGTGCCCCT
AGCTGGCCCAGAGCCGGCAGTGTGAGCCCAAGTCCGGGCTGGAGCCGAGGCCGGAGCAGCTGTCTGGGAGTCAAGGCTGCAGTAGCGTTT
CTTCATGGGGTGCTCCAGGGGGTGCCACAGACCGACAGGCAGCCCAAGGGCCTGGACACCCCTCCCCAGGCAGGTGCTGCCCCAGGAGGA
CTGTCCTCGGGAATGAACCTCCCGCGGGCTTTGGACTGAGGTCCCTGTGGCCTCGGTCTCCTCCCCATGAAGTGGGAGCGAGGCTCCCCA
ATGGTGCTTTTGGCTTTAGTGTACGATGTTTGCTGTGCTTCCCGCCGTGGAGGGCAGAGCCACCCCACATCAGGATCGGACGTGCTACCC
CTCCCGGTCCCGGCCCTGGCCCAGCCAGCCCAGCCCTCGAGGCTCGATGCCTGTGCCAAGGCCAGGGGCAGCCAGAGGGCAGCTGGATGG
CCACGTGCAGGGGTCAAGGCTGGGCCCTGCAGTGGGGCGGGCCGCCAGCCCCAGCAGTTTACAGACGCATGGCTCTTCCTCCCAGAGCAG
CCGGCAGCTACCTGGACCGGAAATGTCCTCATCCCCTCCCTGGGGCCAGGCTCTGCCCTGGCCTTCCTCTGTGAACCCCTCCTTTCTTTG
TGCTGGTGTCTGGGACCAAAAAGGGGGAATATGGGAGGGCAGAGTGGGGAGGGGAGTCCATGGGCCTGGGGCCCCAAGCCGGGGCGTCTG
AGCTCCCCAGGCATGACCAAACCTCAGTGGAGGGGCCTCTGCTTCAGGCCCCGCCTGGCTGACATTCTGAGCCCCCCTCGGAGGCCCCGC
CACAGCCAACCTGCCCAGTCTTTCCTCTGGGCTTGACCCGCCAGGGGAGTTCTCCAGGCCTAGGGCCAGGAGAGAGGCCCTGGCACCCTG
GCGTGGGTGCCCGCCAAACGCCCTGCGACCGCTCAGAAGCACAAATGCTGTCCATGGCCGTGAGGCTGCCTGCCAGGTGAATGGACATAG
CGTGAGAGGCGGTGAGGCCAGGGCTTCCAGCCTCGTGCTGTCTCGGGACTCCTGACCGTGGTGTGCGTGTGTGCCCGTCTGTGACTTTCT
ACTCACCAAGGTTGAAGAAAGGAAACGGGGAAAATCAAAAGGGGTTCAAACCCCACCTCAGTAGGTGGAGGGGAGCGCCTGCCATTGGTT
GTATTTTTGTTCTGAGTTTTCGGTGCCGTGTTCCTAACTACTCCATCCCATGACCTCGCCACACCTACTGGGGCATCTGGCTGGTGCCTG
CTGCCATGGCCAGCCCCCACTCTCACCCTGCACAGGGGGTCTTGCAGCCCCCAGGCCCACAGCCTCGTTGGGAGGACAGGGTGGCCCTGG
GGACAAGAGGGAGGAGCCCAGGGGCTTACCTCACTGAGAGTGCTCCCCAGCAGGCATCCACTACCCCAGGGCCCCCCACATGTCATGGCA
AGGTTGGTAGTGAATGGGCCTGGTTGGGAGCAGCCCCTGGCCCATTGCCCACCCACCCATCTCACTATGCAATTCGAGTTCCAAGCAACA
TTTGCTCCTGCCCTGGGGCCAGCTCTGCCCCAGCCCTGAGAGGGGTGGTGAGGCAGCCCCCTGGACCCCAGAACCCCAGACAAGGGGGCA
GGCGGGGGACCAGGGCCTCTCCTGTGGGATCTTTGTTTTGTGTTTAACCATAATGGTTGTGTACTGAACCACTTCATATTTGTTATATAT
AATATATATATATATAATCTCCTTAAGACTCAGCCTCCTGGTTTACCCCCCCGGCCTGGGCATCTGACCTCCCCCACCCCAGTGTGATTT
AACATCCAGGAACTGAGGCCTGAACCATTTTGCATTTCCCCCTCCTCCAGCCTCTGTAGGGCCATGGCTGTATGTACTGTCGCTGTGTTT
TTTTGTTTTTTTAGAACTGGGTTTGGGGGCTGATTTTTATTTCTTTGGGGGCTTTTTTTCTTGGCAAATACTAAAAATCTCGTCAATGTA

>33532_33532_3_GNA12-TTYH3_GNA12_chr7_2834561_ENST00000407904_TTYH3_chr7_2686486_ENST00000258796_length(amino acids)=598AA_BP=0
MKRRMFPRPCLARMPGSRGSGSTPDGNRKCCRFEHLLIAHPGSRGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQL
YVPALSALWRDSGIREAFSRRSEFQLALLLLGAAALACLALDLLFLLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIAVGF
YGNGETSDGIHRATYSLRHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLGYTAAIPFWRNTAVSL
EVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMVEEY
SVLSGDILQYYLACSPRAANPFQQKLSGSHKALVEMQDVVAELLRTVPWEQPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQ
ALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSETSIPAAAHT

--------------------------------------------------------------
>33532_33532_4_GNA12-TTYH3_GNA12_chr7_2834561_ENST00000407904_TTYH3_chr7_2686486_ENST00000407643_length(transcript)=5091nt_BP=677nt
ATTTAAGCAGCCTCCTTGACTGTAGGTCCGCTGACTGGCTTCCTCCTTGAGAGCACACTCACAGTGCCGGACCGCAGGCACCTCGCCGAT
GTTCCTGTCCACTTGCTTTTTGTATTGCTCCTTCTCCAGTGAGCTTGGAAGCCTCATGCGGGCAAGGCCTTGTCTGTCTGGTTCTCTGTT
GTGTCCTCGGAGCCTGCCACAGTGGCGGCGCTTGGTGGCTTTGACAGGGGACTGGATTGGGTGGAAGGGGCGAGATTAGACCTGGATACA
GTGACGTCCTTGTCAGCCATGCCGAGTGCAGAGCGCCTACTGTATTGTAGGCATTTGAAATGAAACGGAGAATGTTTCCCAGGCCGTGCC
TAGCAAGGATGCCTGGCAGTCGTGGTTCGGGAAGCACACCAGATGGAAACCGAAAGTGCTGCCGTTTTGAGCACCTACTCATTGCACACC
CTGGGTCCAGGGGCTCAAGGGTTCTTGTTGATGCACGAGATAAGCTTGGCATTCCTTGGCAGTATTCTGAAAATGAGAAGCATGGGATGT
TCCTGATGGCCTTCGAGAACAAGGCGGGGCTGCCTGTGGAGCCGGCCACCTTCCAGCTGTACGTCCCGGCCCTGAGCGCACTCTGGAGGG
ATTCTGGCATCAGGGAGGCTTTCAGCCGGAGAAGCGAGTTTCAGCTGGCCCTGCTGCTCCTGGGGGCCGCCGCCCTGGCCTGCCTCGCCC
TGGACCTCCTCTTCCTGCTCTTCTACTCCTTCTGGCTGTGCTGCCGGCGGCGCAAGAGCGAGGAGCACCTGGACGCCGACTGCTGCTGCA
CGGCCTGGTGTGTCATCATCGCCACGCTGGTGTGCAGCGCCGGCATCGCAGTGGGATTCTACGGCAACGGGGAGACCAGTGATGGCATCC
ATAGGGCCACCTACTCGCTCCGCCACGCCAACCGCACGGTGGCCGGGGTCCAGGACCGCGTGTGGGACACGGCGGTGGGGCTGAACCACA
CGGCGGAGCCCAGCCTGCAGACCCTGGAGCGGCAGCTGGCCGGGCGGCCCGAGCCCCTGCGAGCCGTACAGAGGCTGCAGGGCCTGCTGG
AGACGCTGCTGGGCTACACGGCCGCCATCCCCTTTTGGAGGAACACGGCGGTGTCGCTGGAGGTGCTGGCGGAGCAGGTGGATCTCTACG
ACTGGTACAGGGTCTGCCTGCTGGGAGTCCTGGCCCTGGTCATCAGCTGGGGCGCGCTGGGCTTGGAGCTGGCTGTGTCCGTGGGCTCCA
GCGACTTCTGTGTGGACCCTGACGCCTACGTGACCAAAATGGTGGAGGAGTACTCGGTGCTGAGTGGGGACATCCTGCAGTACTACCTGG
CCTGCTCGCCCCGCGCCGCCAACCCCTTCCAGCAGAAGCTGTCGGGCAGCCACAAGGCACTGGTGGAGATGCAGGATGTCGTGGCTGAGC
TTCTGAGGACCGTCCCCTGGGAGCAGCCGGCCACTAAGGACCCCCTCCTCCGCGTCCAGGAGGTGCTGAATGGCACGGAGGTGAACCTGC
AGCACCTCACCGCCCTGGTGGACTGCCGCAGCCTGCATCTGGACTACGTGCAAGCGCTGACCGGCTTCTGCTATGACGGCGTGGAGGGCC
TCATCTACCTGGCCCTCTTCTCCTTCGTCACAGCCCTCATGTTCAGCTCCATCGTCTGCAGCGTCCCGCACACCTGGCAGCAAAAGAGAG
GCCCTGATGAGGACGGGGAGGAGGAGGCCGCTCCAGGGCCGCGGCAGGCGCACGACAGCCTCTACCGCGTCCACATGCCCAGCCTGTACA
GCTGTGGCAGCAGCTACGGCAGTGAGACCAGCATCCCGGCCGCGGCCCACACCGTCAGCAACGCCCCGGTCACTGAGTACATGAGCCAGA
ACGCTAATTTCCAGAACCCCCGCTGTGAGAACACCCCACTCATTGGGCGCGAGTCCCCGCCGCCCTCATACACCTCCAGCATGAGAGCCA
AATACCTCGCCACGAGCCAGCCTCGCCCTGACTCCAGCGGCAGCCACTAGACCGCGCCCGGCAGCCACCCACCCCACGTGCCAACTTCCC
CTCCCCGTGCCAGCACTGCCGCTTCCACCTGGGCCACCCACCGGACCCTCGCACGCCGTGCCAGGCCTGCCCCAGACGCGTCTGCAGGCC
GCTTGCCCTCCTGTCCCCTCCCCGCAGGGGCACAGTGGAGACGCAGGGGCTCTGGGCCCGTACCGCCAACTCGGGTCACACCTGAACGCT
GCTGCCAGCCGATGCCCCAGCCCTGCACGCCACCCACTATCCCGGCACGCTCCCTCTGCAGATGGTCGCCGCACCTACAAGCCCTGGCCG
CACCCAACCTGTGTTGTTGCCGCCCGGCCCTTCCCTCCACAGCTCTCCTTCCTCCCGCCCGGCACTTCTGTGGACCCCTTCTTAGTTCAC
AGGCACGGCTGGGGCCGCTCTGTGCTGGCGCCTGCTGGCCACTGAGGGACAGGGACACGTGCCACCTGCTCATCTCTGCCCTGAGGTCAC
CCCGTGGTCCCTCCACGTGCCCATCTCTCTGCAGTGCCCTCCTCGCCTGTGCAGCCCGCCCACCCACAGGCTCACCCCTCCTGCCGGCTG
CCAGAGGCCCCCTCCAGCAGGGCCTCTCTCCGTTGCCCCAGCTTCACTCTCTCCCTCAGCACCTGCCCTGCTGGAGGCCCCAGCCCTCCG
TGGACAGCAGGGGCCACGTGGAGCCCGGGCCGCTCACCCGCCACCCAGTGCTGGCCGCCTTCTTGGTGCCAAACCCCCTTCCCCCACCCA
GAGACTGGGCAGCTGTGTCTGGTTCGTTCTTTGCACTAACCACATTTGTCATCTCTAGGGCAGGCTGGGGCTGCGGGCTGAGGGGGACCG
CTGGCACCCCCCTTCCCTCCCTTCTTGGTTCCATTTCCATCCATGACAGGTACAGCATCCCAGGAGCCCGGCCTGAGGGGCTGGACCCGA
GCCGGCTGTGAACATCCCTCAGCCCCTGCTGTCCCCCCTTGGGACTAACCACTAACCTCACCCCCAAACTCCACGGGTGCCCCTAGCTGG
CCCAGAGCCGGCAGTGTGAGCCCAAGTCCGGGCTGGAGCCGAGGCCGGAGCAGCTGTCTGGGAGTCAAGGCTGCAGTAGCGTTTCTTCAT
GGGGTGCTCCAGGGGGTGCCACAGACCGACAGGCAGCCCAAGGGCCTGGACACCCCTCCCCAGGCAGGTGCTGCCCCAGGAGGACTGTCC
TCGGGAATGAACCTCCCGCGGGCTTTGGACTGAGGTCCCTGTGGCCTCGGTCTCCTCCCCATGAAGTGGGAGCGAGGCTCCCCAATGGTG
CTTTTGGCTTTAGTGTACGATGTTTGCTGTGCTTCCCGCCGTGGAGGGCAGAGCCACCCCACATCAGGATCGGACGTGCTACCCCTCCCG
GTCCCGGCCCTGGCCCAGCCAGCCCAGCCCTCGAGGCTCGATGCCTGTGCCAAGGCCAGGGGCAGCCAGAGGGCAGCTGGATGGCCACGT
GCAGGGGTCAAGGCTGGGCCCTGCAGTGGGGCGGGCCGCCAGCCCCAGCAGTTTACAGACGCATGGCTCTTCCTCCCAGAGCAGCCGGCA
GCTACCTGGACCGGAAATGTCCTCATCCCCTCCCTGGGGCCAGGCTCTGCCCTGGCCTTCCTCTGTGAACCCCTCCTTTCTTTGTGCTGG
TGTCTGGGACCAAAAAGGGGGAATATGGGAGGGCAGAGTGGGGAGGGGAGTCCATGGGCCTGGGGCCCCAAGCCGGGGCGTCTGAGCTCC
CCAGGCATGACCAAACCTCAGTGGAGGGGCCTCTGCTTCAGGCCCCGCCTGGCTGACATTCTGAGCCCCCCTCGGAGGCCCCGCCACAGC
CAACCTGCCCAGTCTTTCCTCTGGGCTTGACCCGCCAGGGGAGTTCTCCAGGCCTAGGGCCAGGAGAGAGGCCCTGGCACCCTGGCGTGG
GTGCCCGCCAAACGCCCTGCGACCGCTCAGAAGCACAAATGCTGTCCATGGCCGTGAGGCTGCCTGCCAGGTGAATGGACATAGCGTGAG
AGGCGGTGAGGCCAGGGCTTCCAGCCTCGTGCTGTCTCGGGACTCCTGACCGTGGTGTGCGTGTGTGCCCGTCTGTGACTTTCTACTCAC
CAAGGTTGAAGAAAGGAAACGGGGAAAATCAAAAGGGGTTCAAACCCCACCTCAGTAGGTGGAGGGGAGCGCCTGCCATTGGTTGTATTT
TTGTTCTGAGTTTTCGGTGCCGTGTTCCTAACTACTCCATCCCATGACCTCGCCACACCTACTGGGGCATCTGGCTGGTGCCTGCTGCCA
TGGCCAGCCCCCACTCTCACCCTGCACAGGGGGTCTTGCAGCCCCCAGGCCCACAGCCTCGTTGGGAGGACAGGGTGGCCCTGGGGACAA
GAGGGAGGAGCCCAGGGGCTTACCTCACTGAGAGTGCTCCCCAGCAGGCATCCACTACCCCAGGGCCCCCCACATGTCATGGCAAGGTTG
GTAGTGAATGGGCCTGGTTGGGAGCAGCCCCTGGCCCATTGCCCACCCACCCATCTCACTATGCAATTCGAGTTCCAAGCAACATTTGCT
CCTGCCCTGGGGCCAGCTCTGCCCCAGCCCTGAGAGGGGTGGTGAGGCAGCCCCCTGGACCCCAGAACCCCAGACAAGGGGGCAGGCGGG
GGACCAGGGCCTCTCCTGTGGGATCTTTGTTTTGTGTTTAACCATAATGGTTGTGTACTGAACCACTTCATATTTGTTATATATAATATA
TATATATATAATCTCCTTAAGACTCAGCCTCCTGGTTTACCCCCCCGGCCTGGGCATCTGACCTCCCCCACCCCAGTGTGATTTAACATC
CAGGAACTGAGGCCTGAACCATTTTGCATTTCCCCCTCCTCCAGCCTCTGTAGGGCCATGGCTGTATGTACTGTCGCTGTGTTTTTTTGT
TTTTTTAGAACTGGGTTTGGGGGCTGATTTTTATTTCTTTGGGGGCTTTTTTTCTTGGCAAATACTAAAAATCTCGTCAATGTAATTTCT

>33532_33532_4_GNA12-TTYH3_GNA12_chr7_2834561_ENST00000407904_TTYH3_chr7_2686486_ENST00000407643_length(amino acids)=566AA_BP=0
MKRRMFPRPCLARMPGSRGSGSTPDGNRKCCRFEHLLIAHPGSRGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQL
YVPALSALWRDSGIREAFSRRSEFQLALLLLGAAALACLALDLLFLLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIAVGF
YGNGETSDGIHRATYSLRHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLGYTAAIPFWRNTAVSL
EVLAEQVDLYDWYRVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMVEEYSVLSGDILQYYLACSPRAANPFQQKLSGSHKA
LVEMQDVVAELLRTVPWEQPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVC
SVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSETSIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESP

--------------------------------------------------------------
>33532_33532_5_GNA12-TTYH3_GNA12_chr7_2834561_ENST00000544127_TTYH3_chr7_2686486_ENST00000258796_length(transcript)=4892nt_BP=380nt
GCGAGCGGCGCGCGGTCCGGCGCCTGGTGAAGATCCTGCTGCTGGGCGCGGGCGAGAGCGGCAAGTCCACGTTCCTCAAGCAGATGCGCA
TCATCCACGGCCGCGAGTTCGACCAGAAGGCGCTGCTGGAGTTCCGCGACACCATCTTCGACAACATCCTCAAGGGCTCAAGGGTTCTTG
TTGATGCACGAGATAAGCTTGGCATTCCTTGGCAGTATTCTGAAAATGAGAAGCATGGGATGTTCCTGATGGCCTTCGAGAACAAGGCGG
GGCTGCCTGTGGAGCCGGCCACCTTCCAGCTGTACGTCCCGGCCCTGAGCGCACTCTGGAGGGATTCTGGCATCAGGGAGGCTTTCAGCC
GGAGAAGCGAGTTTCAGCTGGCCCTGCTGCTCCTGGGGGCCGCCGCCCTGGCCTGCCTCGCCCTGGACCTCCTCTTCCTGCTCTTCTACT
CCTTCTGGCTGTGCTGCCGGCGGCGCAAGAGCGAGGAGCACCTGGACGCCGACTGCTGCTGCACGGCCTGGTGTGTCATCATCGCCACGC
TGGTGTGCAGCGCCGGCATCGCAGTGGGATTCTACGGCAACGGGGAGACCAGTGATGGCATCCATAGGGCCACCTACTCGCTCCGCCACG
CCAACCGCACGGTGGCCGGGGTCCAGGACCGCGTGTGGGACACGGCGGTGGGGCTGAACCACACGGCGGAGCCCAGCCTGCAGACCCTGG
AGCGGCAGCTGGCCGGGCGGCCCGAGCCCCTGCGAGCCGTACAGAGGCTGCAGGGCCTGCTGGAGACGCTGCTGGGCTACACGGCCGCCA
TCCCCTTTTGGAGGAACACGGCGGTGTCGCTGGAGGTGCTGGCGGAGCAGGTGGATCTCTACGACTGGTACAGGTGGCTGGGCTACCTGG
GCCTGCTGCTGCTGGACGTCATCATCTGCCTCCTGGTGCTGGTTGGCCTCATCCGCAGCTCCAAGGGCATCCTGGTGGGGGTCTGCCTGC
TGGGAGTCCTGGCCCTGGTCATCAGCTGGGGCGCGCTGGGCTTGGAGCTGGCTGTGTCCGTGGGCTCCAGCGACTTCTGTGTGGACCCTG
ACGCCTACGTGACCAAAATGGTGGAGGAGTACTCGGTGCTGAGTGGGGACATCCTGCAGTACTACCTGGCCTGCTCGCCCCGCGCCGCCA
ACCCCTTCCAGCAGAAGCTGTCGGGCAGCCACAAGGCACTGGTGGAGATGCAGGATGTCGTGGCTGAGCTTCTGAGGACCGTCCCCTGGG
AGCAGCCGGCCACTAAGGACCCCCTCCTCCGCGTCCAGGAGGTGCTGAATGGCACGGAGGTGAACCTGCAGCACCTCACCGCCCTGGTGG
ACTGCCGCAGCCTGCATCTGGACTACGTGCAAGCGCTGACCGGCTTCTGCTATGACGGCGTGGAGGGCCTCATCTACCTGGCCCTCTTCT
CCTTCGTCACAGCCCTCATGTTCAGCTCCATCGTCTGCAGCGTCCCGCACACCTGGCAGCAAAAGAGAGGCCCTGATGAGGACGGGGAGG
AGGAGGCCGCTCCAGGGCCGCGGCAGGCGCACGACAGCCTCTACCGCGTCCACATGCCCAGCCTGTACAGCTGTGGCAGCAGCTACGGCA
GTGAGACCAGCATCCCGGCCGCGGCCCACACCGTCAGCAACGCCCCGGTCACTGAGTACATGAGCCAGAACGCTAATTTCCAGAACCCCC
GCTGTGAGAACACCCCACTCATTGGGCGCGAGTCCCCGCCGCCCTCATACACCTCCAGCATGAGAGCCAAATACCTCGCCACGAGCCAGC
CTCGCCCTGACTCCAGCGGCAGCCACTAGACCGCGCCCGGCAGCCACCCACCCCACGTGCCAACTTCCCCTCCCCGTGCCAGCACTGCCG
CTTCCACCTGGGCCACCCACCGGACCCTCGCACGCCGTGCCAGGCCTGCCCCAGACGCGTCTGCAGGCCGCTTGCCCTCCTGTCCCCTCC
CCGCAGGGGCACAGTGGAGACGCAGGGGCTCTGGGCCCGTACCGCCAACTCGGGTCACACCTGAACGCTGCTGCCAGCCGATGCCCCAGC
CCTGCACGCCACCCACTATCCCGGCACGCTCCCTCTGCAGATGGTCGCCGCACCTACAAGCCCTGGCCGCACCCAACCTGTGTTGTTGCC
GCCCGGCCCTTCCCTCCACAGCTCTCCTTCCTCCCGCCCGGCACTTCTGTGGACCCCTTCTTAGTTCACAGGCACGGCTGGGGCCGCTCT
GTGCTGGCGCCTGCTGGCCACTGAGGGACAGGGACACGTGCCACCTGCTCATCTCTGCCCTGAGGTCACCCCGTGGTCCCTCCACGTGCC
CATCTCTCTGCAGTGCCCTCCTCGCCTGTGCAGCCCGCCCACCCACAGGCTCACCCCTCCTGCCGGCTGCCAGAGGCCCCCTCCAGCAGG
GCCTCTCTCCGTTGCCCCAGCTTCACTCTCTCCCTCAGCACCTGCCCTGCTGGAGGCCCCAGCCCTCCGTGGACAGCAGGGGCCACGTGG
AGCCCGGGCCGCTCACCCGCCACCCAGTGCTGGCCGCCTTCTTGGTGCCAAACCCCCTTCCCCCACCCAGAGACTGGGCAGCTGTGTCTG
GTTCGTTCTTTGCACTAACCACATTTGTCATCTCTAGGGCAGGCTGGGGCTGCGGGCTGAGGGGGACCGCTGGCACCCCCCTTCCCTCCC
TTCTTGGTTCCATTTCCATCCATGACAGGTACAGCATCCCAGGAGCCCGGCCTGAGGGGCTGGACCCGAGCCGGCTGTGAACATCCCTCA
GCCCCTGCTGTCCCCCCTTGGGACTAACCACTAACCTCACCCCCAAACTCCACGGGTGCCCCTAGCTGGCCCAGAGCCGGCAGTGTGAGC
CCAAGTCCGGGCTGGAGCCGAGGCCGGAGCAGCTGTCTGGGAGTCAAGGCTGCAGTAGCGTTTCTTCATGGGGTGCTCCAGGGGGTGCCA
CAGACCGACAGGCAGCCCAAGGGCCTGGACACCCCTCCCCAGGCAGGTGCTGCCCCAGGAGGACTGTCCTCGGGAATGAACCTCCCGCGG
GCTTTGGACTGAGGTCCCTGTGGCCTCGGTCTCCTCCCCATGAAGTGGGAGCGAGGCTCCCCAATGGTGCTTTTGGCTTTAGTGTACGAT
GTTTGCTGTGCTTCCCGCCGTGGAGGGCAGAGCCACCCCACATCAGGATCGGACGTGCTACCCCTCCCGGTCCCGGCCCTGGCCCAGCCA
GCCCAGCCCTCGAGGCTCGATGCCTGTGCCAAGGCCAGGGGCAGCCAGAGGGCAGCTGGATGGCCACGTGCAGGGGTCAAGGCTGGGCCC
TGCAGTGGGGCGGGCCGCCAGCCCCAGCAGTTTACAGACGCATGGCTCTTCCTCCCAGAGCAGCCGGCAGCTACCTGGACCGGAAATGTC
CTCATCCCCTCCCTGGGGCCAGGCTCTGCCCTGGCCTTCCTCTGTGAACCCCTCCTTTCTTTGTGCTGGTGTCTGGGACCAAAAAGGGGG
AATATGGGAGGGCAGAGTGGGGAGGGGAGTCCATGGGCCTGGGGCCCCAAGCCGGGGCGTCTGAGCTCCCCAGGCATGACCAAACCTCAG
TGGAGGGGCCTCTGCTTCAGGCCCCGCCTGGCTGACATTCTGAGCCCCCCTCGGAGGCCCCGCCACAGCCAACCTGCCCAGTCTTTCCTC
TGGGCTTGACCCGCCAGGGGAGTTCTCCAGGCCTAGGGCCAGGAGAGAGGCCCTGGCACCCTGGCGTGGGTGCCCGCCAAACGCCCTGCG
ACCGCTCAGAAGCACAAATGCTGTCCATGGCCGTGAGGCTGCCTGCCAGGTGAATGGACATAGCGTGAGAGGCGGTGAGGCCAGGGCTTC
CAGCCTCGTGCTGTCTCGGGACTCCTGACCGTGGTGTGCGTGTGTGCCCGTCTGTGACTTTCTACTCACCAAGGTTGAAGAAAGGAAACG
GGGAAAATCAAAAGGGGTTCAAACCCCACCTCAGTAGGTGGAGGGGAGCGCCTGCCATTGGTTGTATTTTTGTTCTGAGTTTTCGGTGCC
GTGTTCCTAACTACTCCATCCCATGACCTCGCCACACCTACTGGGGCATCTGGCTGGTGCCTGCTGCCATGGCCAGCCCCCACTCTCACC
CTGCACAGGGGGTCTTGCAGCCCCCAGGCCCACAGCCTCGTTGGGAGGACAGGGTGGCCCTGGGGACAAGAGGGAGGAGCCCAGGGGCTT
ACCTCACTGAGAGTGCTCCCCAGCAGGCATCCACTACCCCAGGGCCCCCCACATGTCATGGCAAGGTTGGTAGTGAATGGGCCTGGTTGG
GAGCAGCCCCTGGCCCATTGCCCACCCACCCATCTCACTATGCAATTCGAGTTCCAAGCAACATTTGCTCCTGCCCTGGGGCCAGCTCTG
CCCCAGCCCTGAGAGGGGTGGTGAGGCAGCCCCCTGGACCCCAGAACCCCAGACAAGGGGGCAGGCGGGGGACCAGGGCCTCTCCTGTGG
GATCTTTGTTTTGTGTTTAACCATAATGGTTGTGTACTGAACCACTTCATATTTGTTATATATAATATATATATATATAATCTCCTTAAG
ACTCAGCCTCCTGGTTTACCCCCCCGGCCTGGGCATCTGACCTCCCCCACCCCAGTGTGATTTAACATCCAGGAACTGAGGCCTGAACCA
TTTTGCATTTCCCCCTCCTCCAGCCTCTGTAGGGCCATGGCTGTATGTACTGTCGCTGTGTTTTTTTGTTTTTTTAGAACTGGGTTTGGG
GGCTGATTTTTATTTCTTTGGGGGCTTTTTTTCTTGGCAAATACTAAAAATCTCGTCAATGTAATTTCTGTGGTTTCTATTCAGCTTGGG

>33532_33532_5_GNA12-TTYH3_GNA12_chr7_2834561_ENST00000544127_TTYH3_chr7_2686486_ENST00000258796_length(amino acids)=601AA_BP=1
MVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPAT
FQLYVPALSALWRDSGIREAFSRRSEFQLALLLLGAAALACLALDLLFLLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIA
VGFYGNGETSDGIHRATYSLRHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLGYTAAIPFWRNTA
VSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMV
EEYSVLSGDILQYYLACSPRAANPFQQKLSGSHKALVEMQDVVAELLRTVPWEQPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLD
YVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSETSIPAA

--------------------------------------------------------------
>33532_33532_6_GNA12-TTYH3_GNA12_chr7_2834561_ENST00000544127_TTYH3_chr7_2686486_ENST00000407643_length(transcript)=4794nt_BP=380nt
GCGAGCGGCGCGCGGTCCGGCGCCTGGTGAAGATCCTGCTGCTGGGCGCGGGCGAGAGCGGCAAGTCCACGTTCCTCAAGCAGATGCGCA
TCATCCACGGCCGCGAGTTCGACCAGAAGGCGCTGCTGGAGTTCCGCGACACCATCTTCGACAACATCCTCAAGGGCTCAAGGGTTCTTG
TTGATGCACGAGATAAGCTTGGCATTCCTTGGCAGTATTCTGAAAATGAGAAGCATGGGATGTTCCTGATGGCCTTCGAGAACAAGGCGG
GGCTGCCTGTGGAGCCGGCCACCTTCCAGCTGTACGTCCCGGCCCTGAGCGCACTCTGGAGGGATTCTGGCATCAGGGAGGCTTTCAGCC
GGAGAAGCGAGTTTCAGCTGGCCCTGCTGCTCCTGGGGGCCGCCGCCCTGGCCTGCCTCGCCCTGGACCTCCTCTTCCTGCTCTTCTACT
CCTTCTGGCTGTGCTGCCGGCGGCGCAAGAGCGAGGAGCACCTGGACGCCGACTGCTGCTGCACGGCCTGGTGTGTCATCATCGCCACGC
TGGTGTGCAGCGCCGGCATCGCAGTGGGATTCTACGGCAACGGGGAGACCAGTGATGGCATCCATAGGGCCACCTACTCGCTCCGCCACG
CCAACCGCACGGTGGCCGGGGTCCAGGACCGCGTGTGGGACACGGCGGTGGGGCTGAACCACACGGCGGAGCCCAGCCTGCAGACCCTGG
AGCGGCAGCTGGCCGGGCGGCCCGAGCCCCTGCGAGCCGTACAGAGGCTGCAGGGCCTGCTGGAGACGCTGCTGGGCTACACGGCCGCCA
TCCCCTTTTGGAGGAACACGGCGGTGTCGCTGGAGGTGCTGGCGGAGCAGGTGGATCTCTACGACTGGTACAGGGTCTGCCTGCTGGGAG
TCCTGGCCCTGGTCATCAGCTGGGGCGCGCTGGGCTTGGAGCTGGCTGTGTCCGTGGGCTCCAGCGACTTCTGTGTGGACCCTGACGCCT
ACGTGACCAAAATGGTGGAGGAGTACTCGGTGCTGAGTGGGGACATCCTGCAGTACTACCTGGCCTGCTCGCCCCGCGCCGCCAACCCCT
TCCAGCAGAAGCTGTCGGGCAGCCACAAGGCACTGGTGGAGATGCAGGATGTCGTGGCTGAGCTTCTGAGGACCGTCCCCTGGGAGCAGC
CGGCCACTAAGGACCCCCTCCTCCGCGTCCAGGAGGTGCTGAATGGCACGGAGGTGAACCTGCAGCACCTCACCGCCCTGGTGGACTGCC
GCAGCCTGCATCTGGACTACGTGCAAGCGCTGACCGGCTTCTGCTATGACGGCGTGGAGGGCCTCATCTACCTGGCCCTCTTCTCCTTCG
TCACAGCCCTCATGTTCAGCTCCATCGTCTGCAGCGTCCCGCACACCTGGCAGCAAAAGAGAGGCCCTGATGAGGACGGGGAGGAGGAGG
CCGCTCCAGGGCCGCGGCAGGCGCACGACAGCCTCTACCGCGTCCACATGCCCAGCCTGTACAGCTGTGGCAGCAGCTACGGCAGTGAGA
CCAGCATCCCGGCCGCGGCCCACACCGTCAGCAACGCCCCGGTCACTGAGTACATGAGCCAGAACGCTAATTTCCAGAACCCCCGCTGTG
AGAACACCCCACTCATTGGGCGCGAGTCCCCGCCGCCCTCATACACCTCCAGCATGAGAGCCAAATACCTCGCCACGAGCCAGCCTCGCC
CTGACTCCAGCGGCAGCCACTAGACCGCGCCCGGCAGCCACCCACCCCACGTGCCAACTTCCCCTCCCCGTGCCAGCACTGCCGCTTCCA
CCTGGGCCACCCACCGGACCCTCGCACGCCGTGCCAGGCCTGCCCCAGACGCGTCTGCAGGCCGCTTGCCCTCCTGTCCCCTCCCCGCAG
GGGCACAGTGGAGACGCAGGGGCTCTGGGCCCGTACCGCCAACTCGGGTCACACCTGAACGCTGCTGCCAGCCGATGCCCCAGCCCTGCA
CGCCACCCACTATCCCGGCACGCTCCCTCTGCAGATGGTCGCCGCACCTACAAGCCCTGGCCGCACCCAACCTGTGTTGTTGCCGCCCGG
CCCTTCCCTCCACAGCTCTCCTTCCTCCCGCCCGGCACTTCTGTGGACCCCTTCTTAGTTCACAGGCACGGCTGGGGCCGCTCTGTGCTG
GCGCCTGCTGGCCACTGAGGGACAGGGACACGTGCCACCTGCTCATCTCTGCCCTGAGGTCACCCCGTGGTCCCTCCACGTGCCCATCTC
TCTGCAGTGCCCTCCTCGCCTGTGCAGCCCGCCCACCCACAGGCTCACCCCTCCTGCCGGCTGCCAGAGGCCCCCTCCAGCAGGGCCTCT
CTCCGTTGCCCCAGCTTCACTCTCTCCCTCAGCACCTGCCCTGCTGGAGGCCCCAGCCCTCCGTGGACAGCAGGGGCCACGTGGAGCCCG
GGCCGCTCACCCGCCACCCAGTGCTGGCCGCCTTCTTGGTGCCAAACCCCCTTCCCCCACCCAGAGACTGGGCAGCTGTGTCTGGTTCGT
TCTTTGCACTAACCACATTTGTCATCTCTAGGGCAGGCTGGGGCTGCGGGCTGAGGGGGACCGCTGGCACCCCCCTTCCCTCCCTTCTTG
GTTCCATTTCCATCCATGACAGGTACAGCATCCCAGGAGCCCGGCCTGAGGGGCTGGACCCGAGCCGGCTGTGAACATCCCTCAGCCCCT
GCTGTCCCCCCTTGGGACTAACCACTAACCTCACCCCCAAACTCCACGGGTGCCCCTAGCTGGCCCAGAGCCGGCAGTGTGAGCCCAAGT
CCGGGCTGGAGCCGAGGCCGGAGCAGCTGTCTGGGAGTCAAGGCTGCAGTAGCGTTTCTTCATGGGGTGCTCCAGGGGGTGCCACAGACC
GACAGGCAGCCCAAGGGCCTGGACACCCCTCCCCAGGCAGGTGCTGCCCCAGGAGGACTGTCCTCGGGAATGAACCTCCCGCGGGCTTTG
GACTGAGGTCCCTGTGGCCTCGGTCTCCTCCCCATGAAGTGGGAGCGAGGCTCCCCAATGGTGCTTTTGGCTTTAGTGTACGATGTTTGC
TGTGCTTCCCGCCGTGGAGGGCAGAGCCACCCCACATCAGGATCGGACGTGCTACCCCTCCCGGTCCCGGCCCTGGCCCAGCCAGCCCAG
CCCTCGAGGCTCGATGCCTGTGCCAAGGCCAGGGGCAGCCAGAGGGCAGCTGGATGGCCACGTGCAGGGGTCAAGGCTGGGCCCTGCAGT
GGGGCGGGCCGCCAGCCCCAGCAGTTTACAGACGCATGGCTCTTCCTCCCAGAGCAGCCGGCAGCTACCTGGACCGGAAATGTCCTCATC
CCCTCCCTGGGGCCAGGCTCTGCCCTGGCCTTCCTCTGTGAACCCCTCCTTTCTTTGTGCTGGTGTCTGGGACCAAAAAGGGGGAATATG
GGAGGGCAGAGTGGGGAGGGGAGTCCATGGGCCTGGGGCCCCAAGCCGGGGCGTCTGAGCTCCCCAGGCATGACCAAACCTCAGTGGAGG
GGCCTCTGCTTCAGGCCCCGCCTGGCTGACATTCTGAGCCCCCCTCGGAGGCCCCGCCACAGCCAACCTGCCCAGTCTTTCCTCTGGGCT
TGACCCGCCAGGGGAGTTCTCCAGGCCTAGGGCCAGGAGAGAGGCCCTGGCACCCTGGCGTGGGTGCCCGCCAAACGCCCTGCGACCGCT
CAGAAGCACAAATGCTGTCCATGGCCGTGAGGCTGCCTGCCAGGTGAATGGACATAGCGTGAGAGGCGGTGAGGCCAGGGCTTCCAGCCT
CGTGCTGTCTCGGGACTCCTGACCGTGGTGTGCGTGTGTGCCCGTCTGTGACTTTCTACTCACCAAGGTTGAAGAAAGGAAACGGGGAAA
ATCAAAAGGGGTTCAAACCCCACCTCAGTAGGTGGAGGGGAGCGCCTGCCATTGGTTGTATTTTTGTTCTGAGTTTTCGGTGCCGTGTTC
CTAACTACTCCATCCCATGACCTCGCCACACCTACTGGGGCATCTGGCTGGTGCCTGCTGCCATGGCCAGCCCCCACTCTCACCCTGCAC
AGGGGGTCTTGCAGCCCCCAGGCCCACAGCCTCGTTGGGAGGACAGGGTGGCCCTGGGGACAAGAGGGAGGAGCCCAGGGGCTTACCTCA
CTGAGAGTGCTCCCCAGCAGGCATCCACTACCCCAGGGCCCCCCACATGTCATGGCAAGGTTGGTAGTGAATGGGCCTGGTTGGGAGCAG
CCCCTGGCCCATTGCCCACCCACCCATCTCACTATGCAATTCGAGTTCCAAGCAACATTTGCTCCTGCCCTGGGGCCAGCTCTGCCCCAG
CCCTGAGAGGGGTGGTGAGGCAGCCCCCTGGACCCCAGAACCCCAGACAAGGGGGCAGGCGGGGGACCAGGGCCTCTCCTGTGGGATCTT
TGTTTTGTGTTTAACCATAATGGTTGTGTACTGAACCACTTCATATTTGTTATATATAATATATATATATATAATCTCCTTAAGACTCAG
CCTCCTGGTTTACCCCCCCGGCCTGGGCATCTGACCTCCCCCACCCCAGTGTGATTTAACATCCAGGAACTGAGGCCTGAACCATTTTGC
ATTTCCCCCTCCTCCAGCCTCTGTAGGGCCATGGCTGTATGTACTGTCGCTGTGTTTTTTTGTTTTTTTAGAACTGGGTTTGGGGGCTGA
TTTTTATTTCTTTGGGGGCTTTTTTTCTTGGCAAATACTAAAAATCTCGTCAATGTAATTTCTGTGGTTTCTATTCAGCTTGGGTTTCAT

>33532_33532_6_GNA12-TTYH3_GNA12_chr7_2834561_ENST00000544127_TTYH3_chr7_2686486_ENST00000407643_length(amino acids)=569AA_BP=1
MVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPAT
FQLYVPALSALWRDSGIREAFSRRSEFQLALLLLGAAALACLALDLLFLLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIA
VGFYGNGETSDGIHRATYSLRHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLGYTAAIPFWRNTA
VSLEVLAEQVDLYDWYRVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMVEEYSVLSGDILQYYLACSPRAANPFQQKLSGS
HKALVEMQDVVAELLRTVPWEQPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSS
IVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSETSIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for GNA12-TTYH3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GNA12-TTYH3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GNA12-TTYH3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource