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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GNAS-ITGAV (FusionGDB2 ID:33630)

Fusion Gene Summary for GNAS-ITGAV

check button Fusion gene summary
Fusion gene informationFusion gene name: GNAS-ITGAV
Fusion gene ID: 33630
HgeneTgene
Gene symbol

GNAS

ITGAV

Gene ID

2778

3685

Gene nameGNAS complex locusintegrin subunit alpha V
SynonymsAHO|C20orf45|GNAS1|GPSA|GSA|GSP|NESP|PITA3|POH|SCG6|SgVICD51|MSK8|VNRA|VTNR
Cytomap

20q13.32

2q32.1

Type of geneprotein-codingprotein-coding
Descriptionprotein ALEXprotein GNASprotein SCG6 (secretogranin VI)G protein subunit alpha Sadenylate cyclase-stimulating G alpha proteinalternative gene product encoded by XL-exonextra large alphas proteinguanine nucleotide binding protein (G protein), alpha integrin alpha-Vantigen identified by monoclonal antibody L230integrin alphaVbeta3integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)vitronectin receptor subunit alpha
Modification date2020032920200313
UniProtAcc

P63092

P06756

Ensembl transtripts involved in fusion geneENST00000265620, ENST00000306090, 
ENST00000313949, ENST00000354359, 
ENST00000371075, ENST00000371085, 
ENST00000371095, ENST00000371100, 
ENST00000371102, ENST00000464624, 
ENST00000306120, ENST00000371081, 
ENST00000371098, ENST00000371099, 
ENST00000474571, ENST00000261023, 
ENST00000374907, ENST00000433736, 
Fusion gene scores* DoF score44 X 25 X 16=176009 X 8 X 6=432
# samples 519
** MAII scorelog2(51/17600*10)=-5.10893437155316
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/432*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GNAS [Title/Abstract] AND ITGAV [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGNAS(57486241)-ITGAV(187540547), # samples:1
Anticipated loss of major functional domain due to fusion event.GNAS-ITGAV seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
GNAS-ITGAV seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
GNAS-ITGAV seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
GNAS-ITGAV seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
GNAS-ITGAV seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneITGAV

GO:0007155

cell adhesion

10218736

TgeneITGAV

GO:0008284

positive regulation of cell proliferation

19578119

TgeneITGAV

GO:0033627

cell adhesion mediated by integrin

12807887|17158881

TgeneITGAV

GO:0034446

substrate adhesion-dependent cell spreading

24658351

TgeneITGAV

GO:0045785

positive regulation of cell adhesion

10708943

TgeneITGAV

GO:0050764

regulation of phagocytosis

10570297

TgeneITGAV

GO:0070588

calcium ion transmembrane transport

18395422

TgeneITGAV

GO:1901388

regulation of transforming growth factor beta activation

22278742

TgeneITGAV

GO:2000536

negative regulation of entry of bacterium into host cell

10570297


check buttonFusion gene breakpoints across GNAS (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ITGAV (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CV-5978-01AGNASchr20

57486241

-ITGAVchr2

187540547

+


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Fusion Gene ORF analysis for GNAS-ITGAV

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000265620ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+
5CDS-intronENST00000306090ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+
5CDS-intronENST00000313949ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+
5CDS-intronENST00000354359ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+
5CDS-intronENST00000371075ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+
5CDS-intronENST00000371085ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+
5CDS-intronENST00000371095ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+
5CDS-intronENST00000371100ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+
5CDS-intronENST00000371102ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+
5CDS-intronENST00000464624ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+
Frame-shiftENST00000313949ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
Frame-shiftENST00000313949ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
Frame-shiftENST00000313949ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
Frame-shiftENST00000371075ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
Frame-shiftENST00000371075ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
Frame-shiftENST00000371075ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
Frame-shiftENST00000464624ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
Frame-shiftENST00000464624ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
Frame-shiftENST00000464624ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000265620ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000265620ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000265620ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000306090ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000306090ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000306090ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000354359ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000354359ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000354359ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000371085ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000371085ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000371085ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000371095ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000371095ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000371095ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000371100ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000371100ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000371100ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000371102ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000371102ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
In-frameENST00000371102ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-3CDSENST00000306120ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-3CDSENST00000306120ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-3CDSENST00000306120ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-3CDSENST00000371081ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-3CDSENST00000371081ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-3CDSENST00000371081ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-3CDSENST00000371098ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-3CDSENST00000371098ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-3CDSENST00000371098ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-3CDSENST00000371099ENST00000261023GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-3CDSENST00000371099ENST00000374907GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-3CDSENST00000371099ENST00000433736GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-intronENST00000306120ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-intronENST00000371081ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-intronENST00000371098ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+
intron-intronENST00000371099ENST00000474571GNASchr20

57486241

-ITGAVchr2

187540547

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000371100GNASchr2057486241-ENST00000261023ITGAVchr2187540547+7965402953136651044
ENST00000371100GNASchr2057486241-ENST00000374907ITGAVchr2187540547+7961402953136651044
ENST00000371100GNASchr2057486241-ENST00000433736ITGAVchr2187540547+4505402953136651044
ENST00000371102GNASchr2057486241-ENST00000261023ITGAVchr2187540547+73743438330741023
ENST00000371102GNASchr2057486241-ENST00000374907ITGAVchr2187540547+73703438330741023
ENST00000371102GNASchr2057486241-ENST00000433736ITGAVchr2187540547+39143438330741023
ENST00000371095GNASchr2057486241-ENST00000261023ITGAVchr2187540547+5867193115822527
ENST00000371095GNASchr2057486241-ENST00000374907ITGAVchr2187540547+586319314251567380
ENST00000371095GNASchr2057486241-ENST00000433736ITGAVchr2187540547+240719314251567380
ENST00000371085GNASchr2057486241-ENST00000261023ITGAVchr2187540547+5908197216231541
ENST00000371085GNASchr2057486241-ENST00000374907ITGAVchr2187540547+590419724241608394
ENST00000371085GNASchr2057486241-ENST00000433736ITGAVchr2187540547+244819724241608394
ENST00000354359GNASchr2057486241-ENST00000261023ITGAVchr2187540547+5911197516261542
ENST00000354359GNASchr2057486241-ENST00000374907ITGAVchr2187540547+590719754241611395
ENST00000354359GNASchr2057486241-ENST00000433736ITGAVchr2187540547+245119754241611395
ENST00000265620GNASchr2057486241-ENST00000261023ITGAVchr2187540547+5802186615170506
ENST00000265620GNASchr2057486241-ENST00000374907ITGAVchr2187540547+579818663631502379
ENST00000265620GNASchr2057486241-ENST00000433736ITGAVchr2187540547+234218663631502379
ENST00000306090GNASchr2057486241-ENST00000261023ITGAVchr2187540547+5578164212991433
ENST00000306090GNASchr2057486241-ENST00000374907ITGAVchr2187540547+557416421421284380
ENST00000306090GNASchr2057486241-ENST00000433736ITGAVchr2187540547+211816421421284380

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000371100ENST00000261023GNASchr2057486241-ITGAVchr2187540547+0.0006243830.99937564
ENST00000371100ENST00000374907GNASchr2057486241-ITGAVchr2187540547+0.0006242260.99937576
ENST00000371100ENST00000433736GNASchr2057486241-ITGAVchr2187540547+0.0052110320.994789
ENST00000371102ENST00000261023GNASchr2057486241-ITGAVchr2187540547+0.0002554580.9997446
ENST00000371102ENST00000374907GNASchr2057486241-ITGAVchr2187540547+0.0002554880.9997445
ENST00000371102ENST00000433736GNASchr2057486241-ITGAVchr2187540547+0.0032753260.99672467
ENST00000371095ENST00000261023GNASchr2057486241-ITGAVchr2187540547+0.0002261620.9997738
ENST00000371095ENST00000374907GNASchr2057486241-ITGAVchr2187540547+0.0002214090.99977857
ENST00000371095ENST00000433736GNASchr2057486241-ITGAVchr2187540547+0.0035418740.9964581
ENST00000371085ENST00000261023GNASchr2057486241-ITGAVchr2187540547+0.0002298990.9997701
ENST00000371085ENST00000374907GNASchr2057486241-ITGAVchr2187540547+0.0002260840.9997739
ENST00000371085ENST00000433736GNASchr2057486241-ITGAVchr2187540547+0.0036014380.99639857
ENST00000354359ENST00000261023GNASchr2057486241-ITGAVchr2187540547+0.000186480.9998135
ENST00000354359ENST00000374907GNASchr2057486241-ITGAVchr2187540547+0.0001834630.9998166
ENST00000354359ENST00000433736GNASchr2057486241-ITGAVchr2187540547+0.0027453620.99725467
ENST00000265620ENST00000261023GNASchr2057486241-ITGAVchr2187540547+0.0001323080.9998677
ENST00000265620ENST00000374907GNASchr2057486241-ITGAVchr2187540547+0.0001294530.99987054
ENST00000265620ENST00000433736GNASchr2057486241-ITGAVchr2187540547+0.002216310.9977837
ENST00000306090ENST00000261023GNASchr2057486241-ITGAVchr2187540547+0.0002143710.9997856
ENST00000306090ENST00000374907GNASchr2057486241-ITGAVchr2187540547+0.0002094720.9997905
ENST00000306090ENST00000433736GNASchr2057486241-ITGAVchr2187540547+0.0032844330.99671555

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Fusion Genomic Features for GNAS-ITGAV


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GNAS-ITGAV


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:57486241/chr2:187540547)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GNAS

P63092

ITGAV

P06756

FUNCTION: Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) (PubMed:17110384). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP (PubMed:26206488, PubMed:8702665). GNAS functions downstream of several GPCRs, including beta-adrenergic receptors (PubMed:21488135). Stimulates the Ras signaling pathway via RAPGEF2 (PubMed:12391161). {ECO:0000269|PubMed:12391161, ECO:0000269|PubMed:17110384, ECO:0000269|PubMed:21488135, ECO:0000269|PubMed:26206488, ECO:0000269|PubMed:8702665}.FUNCTION: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed:23125415). ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling (PubMed:18441324). ITGAV:ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling (PubMed:28302677). ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:19578119). ITGAV:ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464). ITGAV:ITGB3 binds to IL1B and this binding is essential for IL1B signaling (PubMed:29030430). ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGAV:ITGB3 and ITGAV:ITGB6 act as a receptor for fibrillin-1 (FBN1) and mediate R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881). Integrin alpha-V/beta-6 or alpha-V/beta-8 (ITGAV:ITGB6 or ITGAV:ITGB8) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (PubMed:15184403, PubMed:22278742, PubMed:28117447). ITGAV:ITGB3 act as a receptor for CD40LG (PubMed:31331973). {ECO:0000269|PubMed:12807887, ECO:0000269|PubMed:15184403, ECO:0000269|PubMed:17158881, ECO:0000269|PubMed:18441324, ECO:0000269|PubMed:18635536, ECO:0000269|PubMed:19578119, ECO:0000269|PubMed:20682778, ECO:0000269|PubMed:22278742, ECO:0000269|PubMed:23125415, ECO:0000269|PubMed:25398877, ECO:0000269|PubMed:28117447, ECO:0000269|PubMed:28302677, ECO:0000269|PubMed:28873464, ECO:0000269|PubMed:29030430, ECO:0000269|PubMed:31331973}.; FUNCTION: (Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for Adenovirus type C. {ECO:0000269|PubMed:20615244}.; FUNCTION: (Microbial infection) Integrin ITGAV:ITGB5 and ITGAV:ITGB3 act as receptors for Coxsackievirus A9 and B1. {ECO:0000269|PubMed:15194773, ECO:0000269|PubMed:7519807, ECO:0000269|PubMed:9426447}.; FUNCTION: (Microbial infection) Integrin ITGAV:ITGB3 acts as a receptor for Herpes virus 8/HHV-8. {ECO:0000269|PubMed:18045938}.; FUNCTION: (Microbial infection) Integrin ITGAV:ITGB6 acts as a receptor for herpes simplex 1/HHV-1. {ECO:0000269|PubMed:24367260}.; FUNCTION: (Microbial infection) Integrin ITGAV:ITGB3 acts as a receptor for Human parechovirus 1. {ECO:0000269|PubMed:11160695}.; FUNCTION: (Microbial infection) Integrin ITGAV:ITGB3 acts as a receptor for West nile virus. {ECO:0000269|PubMed:23658209}.; FUNCTION: (Microbial infection) In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. {ECO:0000269|PubMed:10397733}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGNASchr20:57486241chr2:187540547ENST00000371100-1313641_66711591038.0Coiled coilOntology_term=ECO:0000255
HgeneGNASchr20:57486241chr2:187540547ENST00000371100-1313730_75611591038.0Coiled coilOntology_term=ECO:0000255
HgeneGNASchr20:57486241chr2:187540547ENST00000371102-1212641_66711451024.0Coiled coilOntology_term=ECO:0000255
HgeneGNASchr20:57486241chr2:187540547ENST00000371102-1212730_75611451024.0Coiled coilOntology_term=ECO:0000255
HgeneGNASchr20:57486241chr2:187540547ENST00000313949-131378_14272926.333333333333332Compositional biasGlu-rich
HgeneGNASchr20:57486241chr2:187540547ENST00000371075-131378_14273036.333333333333336Compositional biasGlu-rich
HgeneGNASchr20:57486241chr2:187540547ENST00000371100-1313358_52211591038.0Compositional biasAla-rich
HgeneGNASchr20:57486241chr2:187540547ENST00000371102-1212358_52211451024.0Compositional biasAla-rich
HgeneGNASchr20:57486241chr2:187540547ENST00000265620-121239_394501380.0DomainG-alpha
HgeneGNASchr20:57486241chr2:187540547ENST00000306090-131339_394500381.0DomainG-alpha
HgeneGNASchr20:57486241chr2:187540547ENST00000354359-131339_394517396.0DomainG-alpha
HgeneGNASchr20:57486241chr2:187540547ENST00000371085-131339_394516395.0DomainG-alpha
HgeneGNASchr20:57486241chr2:187540547ENST00000371095-121239_394502381.0DomainG-alpha
HgeneGNASchr20:57486241chr2:187540547ENST00000371100-1313682_103711591038.0DomainG-alpha
HgeneGNASchr20:57486241chr2:187540547ENST00000371102-1212682_103711451024.0DomainG-alpha
HgeneGNASchr20:57486241chr2:187540547ENST00000265620-1212197_204501380.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000265620-1212223_227501380.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000265620-1212292_295501380.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000265620-121247_55501380.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000306090-1313197_204500381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000306090-1313223_227500381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000306090-1313292_295500381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000306090-131347_55500381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000354359-1313197_204517396.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000354359-1313223_227517396.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000354359-1313292_295517396.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000354359-131347_55517396.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371085-1313197_204516395.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371085-1313223_227516395.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371085-1313292_295516395.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371085-131347_55516395.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371095-1212197_204502381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371095-1212223_227502381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371095-1212292_295502381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371095-121247_55502381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371100-1313690_69811591038.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371100-1313840_84711591038.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371100-1313866_87011591038.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371100-1313935_93811591038.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371102-1212690_69811451024.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371102-1212840_84711451024.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371102-1212866_87011451024.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000371102-1212935_93811451024.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr2:187540547ENST00000265620-1212196_204501380.0RegionG2 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000265620-1212219_228501380.0RegionG3 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000265620-1212288_295501380.0RegionG4 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000265620-1212364_369501380.0RegionG5 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000265620-121242_55501380.0RegionG1 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000306090-1313196_204500381.0RegionG2 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000306090-1313219_228500381.0RegionG3 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000306090-1313288_295500381.0RegionG4 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000306090-1313364_369500381.0RegionG5 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000306090-131342_55500381.0RegionG1 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000354359-1313196_204517396.0RegionG2 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000354359-1313219_228517396.0RegionG3 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000354359-1313288_295517396.0RegionG4 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000354359-1313364_369517396.0RegionG5 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000354359-131342_55517396.0RegionG1 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371085-1313196_204516395.0RegionG2 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371085-1313219_228516395.0RegionG3 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371085-1313288_295516395.0RegionG4 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371085-1313364_369516395.0RegionG5 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371085-131342_55516395.0RegionG1 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371095-1212196_204502381.0RegionG2 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371095-1212219_228502381.0RegionG3 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371095-1212288_295502381.0RegionG4 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371095-1212364_369502381.0RegionG5 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371095-121242_55502381.0RegionG1 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371100-13131007_101211591038.0RegionG5 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371100-1313685_69811591038.0RegionG1 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371100-1313839_84711591038.0RegionG2 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371100-1313862_87111591038.0RegionG3 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371100-1313931_93811591038.0RegionG4 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371102-12121007_101211451024.0RegionG5 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371102-1212685_69811451024.0RegionG1 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371102-1212839_84711451024.0RegionG2 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371102-1212862_87111451024.0RegionG3 motif
HgeneGNASchr20:57486241chr2:187540547ENST00000371102-1212931_93811451024.0RegionG4 motif
TgeneITGAVchr20:57486241chr2:187540547ENST0000026102326301019_10239401049.0MotifNote=GFFKR motif
TgeneITGAVchr20:57486241chr2:187540547ENST0000037490724281019_10239041013.0MotifNote=GFFKR motif
TgeneITGAVchr20:57486241chr2:187540547ENST0000043373626301019_10238941003.0MotifNote=GFFKR motif
TgeneITGAVchr20:57486241chr2:187540547ENST0000026102326301017_10489401049.0Topological domainCytoplasmic
TgeneITGAVchr20:57486241chr2:187540547ENST0000037490724281017_10489041013.0Topological domainCytoplasmic
TgeneITGAVchr20:57486241chr2:187540547ENST0000043373626301017_10488941003.0Topological domainCytoplasmic
TgeneITGAVchr20:57486241chr2:187540547ENST000002610232630993_10169401049.0TransmembraneHelical
TgeneITGAVchr20:57486241chr2:187540547ENST000003749072428993_10169041013.0TransmembraneHelical
TgeneITGAVchr20:57486241chr2:187540547ENST000004337362630993_10168941003.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGNASchr20:57486241chr2:187540547ENST00000306120-11238_4760626.0Compositional biasPro-rich
HgeneGNASchr20:57486241chr2:187540547ENST00000371098-1478_142020.333333333333332Compositional biasGlu-rich
TgeneITGAVchr20:57486241chr2:187540547ENST000002610232630260_2689401049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr20:57486241chr2:187540547ENST000002610232630314_3229401049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr20:57486241chr2:187540547ENST000002610232630379_3879401049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr20:57486241chr2:187540547ENST000002610232630443_4519401049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr20:57486241chr2:187540547ENST000003749072428260_2689041013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr20:57486241chr2:187540547ENST000003749072428314_3229041013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr20:57486241chr2:187540547ENST000003749072428379_3879041013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr20:57486241chr2:187540547ENST000003749072428443_4519041013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr20:57486241chr2:187540547ENST000004337362630260_2688941003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr20:57486241chr2:187540547ENST000004337362630314_3228941003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr20:57486241chr2:187540547ENST000004337362630379_3878941003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr20:57486241chr2:187540547ENST000004337362630443_4518941003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr20:57486241chr2:187540547ENST000002610232630109_1709401049.0RepeatFG-GAP 2
TgeneITGAVchr20:57486241chr2:187540547ENST000002610232630173_2259401049.0RepeatFG-GAP 3
TgeneITGAVchr20:57486241chr2:187540547ENST000002610232630237_2919401049.0RepeatFG-GAP 4
TgeneITGAVchr20:57486241chr2:187540547ENST000002610232630292_3579401049.0RepeatFG-GAP 5
TgeneITGAVchr20:57486241chr2:187540547ENST00000261023263032_989401049.0RepeatFG-GAP 1
TgeneITGAVchr20:57486241chr2:187540547ENST000002610232630358_4159401049.0RepeatFG-GAP 6
TgeneITGAVchr20:57486241chr2:187540547ENST000002610232630419_4829401049.0RepeatFG-GAP 7
TgeneITGAVchr20:57486241chr2:187540547ENST000003749072428109_1709041013.0RepeatFG-GAP 2
TgeneITGAVchr20:57486241chr2:187540547ENST000003749072428173_2259041013.0RepeatFG-GAP 3
TgeneITGAVchr20:57486241chr2:187540547ENST000003749072428237_2919041013.0RepeatFG-GAP 4
TgeneITGAVchr20:57486241chr2:187540547ENST000003749072428292_3579041013.0RepeatFG-GAP 5
TgeneITGAVchr20:57486241chr2:187540547ENST00000374907242832_989041013.0RepeatFG-GAP 1
TgeneITGAVchr20:57486241chr2:187540547ENST000003749072428358_4159041013.0RepeatFG-GAP 6
TgeneITGAVchr20:57486241chr2:187540547ENST000003749072428419_4829041013.0RepeatFG-GAP 7
TgeneITGAVchr20:57486241chr2:187540547ENST000004337362630109_1708941003.0RepeatFG-GAP 2
TgeneITGAVchr20:57486241chr2:187540547ENST000004337362630173_2258941003.0RepeatFG-GAP 3
TgeneITGAVchr20:57486241chr2:187540547ENST000004337362630237_2918941003.0RepeatFG-GAP 4
TgeneITGAVchr20:57486241chr2:187540547ENST000004337362630292_3578941003.0RepeatFG-GAP 5
TgeneITGAVchr20:57486241chr2:187540547ENST00000433736263032_988941003.0RepeatFG-GAP 1
TgeneITGAVchr20:57486241chr2:187540547ENST000004337362630358_4158941003.0RepeatFG-GAP 6
TgeneITGAVchr20:57486241chr2:187540547ENST000004337362630419_4828941003.0RepeatFG-GAP 7
TgeneITGAVchr20:57486241chr2:187540547ENST00000261023263031_9929401049.0Topological domainExtracellular
TgeneITGAVchr20:57486241chr2:187540547ENST00000374907242831_9929041013.0Topological domainExtracellular
TgeneITGAVchr20:57486241chr2:187540547ENST00000433736263031_9928941003.0Topological domainExtracellular


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Fusion Gene Sequence for GNAS-ITGAV


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>33630_33630_1_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000265620_ITGAV_chr2_187540547_ENST00000261023_length(transcript)=5802nt_BP=1866nt
GGGCGGCGGCGGGGGCCCGGCCGAGGCAATAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCT
CGGCCCGGCGGCGGCCATCAGCCCCCTCGGCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTT
CCCGCCCGTCCGCGCGCCCCGCGGCCCGCGGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCG
CCCGGCGCTGCCCCGGCCCTCCCGGCCCGCGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCC
GCCATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAG
CTGCAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAG
ATGAGGATCCTGCATGTTAATGGGTTTAATGGAGATGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAA
ACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTG
ATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAA
CGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGAT
CAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTG
GGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAAC
ATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACC
ATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAA
TTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAG
TTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGT
GTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAG
CCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCT
TCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAG
GAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAA
TGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAATCAGAATCATTCCTAT
TCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACC
ACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTG
GCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCT
CATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATA
GATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCACAAAATGAGAATTATATTT
GTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAACATAGGGTGACTTGTGTTTTTAGGTATTTAAATAATAAAATTTCAA
GGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGATTTACTACTTTATATAAAATAGTACCTCCTTCAGTTACTGTTTCTGA
TTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTTTAAAGCAGTCCAAATTTGGACCTTAGCAATCATGTCT
TTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTACTTTTCAGAATACTAAAGACTTTATAACTGCATGAACTTGGATTTT
TTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATACCATCCAAATTCTTGCTTTTAATAACAAAGGTACAATATTTTGTTT
TAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATTAAATCCACAATATTTTATTACATTTTTAACTTGTATAAATTTTAGG
TCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAATCACAAATGGCTCTTTTGTGTAATTGTTTAATTTCACCTGAATATCA
TAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCATATTTATTCCATTGTTTTAGTCTGGCTATTTACAGTATAAAAAAAGC
ATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTATGCATATAGTAAGTATTACATTCTTAGAGTAGAGCAGAGTTTTTAGT
TAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATATTTCCAAAACTGTTACTGAGAATGGGTCAAGATCAGTGAGAAATCTT
TACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGTAATGCTTGGAATAAAAACTCTTAAGGCAACTCACTGATTTACTTCT
AGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAAGGTAATGTGTAAAATCAGTCTCGGCTGTCAGAATAACTTCTAAAAG
GTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCTTTCTGAAGTTCGTTAGTATAAATTACTTTTCTAGGATTATTAATAA
AAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGAGTGGTGAACCTTCTAGAGGAATATATGATTTATTCACAGTTCCTCA
AGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTACATCATGTTGTACATTAGAAATGGAGAGTTTAATAGCTCTTTAACT
GCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTGACTATTTTGCTGTGTTTTAAAAATGATTGAAATTTATCTTGCCATA
TCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAATATATTCGTAAAATAGGAGCACATTTAGTTGAGGTATACAAGGTAGG
ACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAAGTAATGGGTCTTGGAGTATAGATTTTTATTAGTAGCTTGAAAGAGC
TTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAATTTTTTAAGAAAAATATTTTTATCCTAGGGCCAAGTGTTGCCTGCC
ACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTTTTACCACCTAGTAACAGTCATTTCTGAAAATATGTTGGATAGAAAG
TCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTATTCCTTTTATGGCATCTATCTTGAAAGTAATCTTGTATTGGAGATT
GAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTACCTTTATGAAATATAGTTTTGTATAATAGCATAGATTTTCCTTCAAA
AAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATTTGAAAGCCTACTTTCTGAAGAAAATGGTGGGATTTTTTTTTATCAT
GATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTAAAACATTTGAAATACTACCATATTTGTGATTTATTGAGAATAAAAA
TCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAAGAAAACATGAATGAACTAGAAGATATTAAAAACATTTGACATTGGT
AAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATTTCAGAATTGATATTTTGAGAAAAATACATGTGAGTCATTTTTTCTG
TTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGAAAGGTAAAACAATTAGTCAAAATATTATTGCCATCATTCTACCTGT
GTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTACATTTCCATAAAGAAAACTCAAGTATTAATAAAAGAGACTTTACTGG
CTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCTAAGGGAGAGATTTGTGTGATAAAAGTATTGTATATAATAGATCAGC
GATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCCTAAGTTGCAAAATGTAATGATGAGCTTGGTGGAGAAGAATGAGTCG
TTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCACCTTGTTTGCATTCTTGGATAGCTTGTATATGTAGTAGTTTGATGAA
TAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGATCAAAAAAGGCAGATGAAATTACTTAATACTCAGTGTTTTGGAGAG
TATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAATATGCAGCATGCAATATATGCTTATATTTCATTTTAATTTCTGATAT
ATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTTGTCATTGTTCTCAAGTGCAATATAACAATGTAACCAAATCTAGATA
ATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAATATTTGTATTATTTTTGTTAGCAGGAAAGAGTGATTAAGTGAGGTTA
TTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAAATGAATTATTCTTTACCAGTTTTGAAACACTTTGAAATATCCTAAG
GTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTAATAACATAGAAAGTAAATATCTTTGTGGTCACCCACATTGGGTGAG
ACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGATTTGAGTTAGTGAAAACTGGTACAGTGTTCTGCTTGATTTACAACA

>33630_33630_1_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000265620_ITGAV_chr2_187540547_ENST00000261023_length(amino acids)=506AA_BP=
MGVPFLEQLVLTKVHALNDVTAVVEHTADVLSVHSAGEMRVAVVTPISTGSADPQKLISNEVLGPGHAWVLSGLGSSILRSSVASKFWKV
VLNLRFPSKDFLSEQILLVEEQDHRDGAQPSVVPDALEEVQSLLQAVGLVVLPDDHVVAAAGHHEDDGSHIVEALDPLAAFIALATHVKH
VEVDFVHLELGLKDSRSQDTAAKQVLIARHIVSLLDHVDLVQEVLGTVNQLVLVGAFVAGTHSFILPQSLGMLIEFGREVKVRHVHHTQD
VVHSELVLGVGQLHGGHQVAHGGHNGFNRLFQVVFDVLHFGCLLISIKPINMQDPHLLHNGAFTRFSSTQQQQAVRGPVDLLVLLQLLLD
LFVGLTLRLLLVALVLGLTVPEAAHGGGGGGGARPGCGGGGRGRPHAGREGRGSAGRAGRARARLLGKERAGRTAGRGPRGARTGGKGRV

--------------------------------------------------------------
>33630_33630_2_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000265620_ITGAV_chr2_187540547_ENST00000374907_length(transcript)=5798nt_BP=1866nt
GGGCGGCGGCGGGGGCCCGGCCGAGGCAATAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCT
CGGCCCGGCGGCGGCCATCAGCCCCCTCGGCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTT
CCCGCCCGTCCGCGCGCCCCGCGGCCCGCGGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCG
CCCGGCGCTGCCCCGGCCCTCCCGGCCCGCGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCC
GCCATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAG
CTGCAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAG
ATGAGGATCCTGCATGTTAATGGGTTTAATGGAGATGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAA
ACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTG
ATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAA
CGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGAT
CAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTG
GGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAAC
ATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACC
ATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAA
TTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAG
TTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGT
GTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAG
CCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCT
TCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAG
GAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAA
TGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAATCAGAATCATTCCTAT
TCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACC
ACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTG
GCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCT
CATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATA
GATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCACAAAATGAGAATTATATTT
GTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAACATAGGGTGACTTGTGTTTTTAGGTATTTAAATAATAAAATTTCAA
GGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGATTTACTACTTTATATAAAATAGTACCTCCTTCAGTTACTGTTTCTGA
TTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTTTAAAGCAGTCCAAATTTGGACCTTAGCAATCATGTCT
TTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTACTTTTCAGAATACTAAAGACTTTATAACTGCATGAACTTGGATTTT
TTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATACCATCCAAATTCTTGCTTTTAATAACAAAGGTACAATATTTTGTTT
TAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATTAAATCCACAATATTTTATTACATTTTTAACTTGTATAAATTTTAGG
TCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAATCACAAATGGCTCTTTTGTGTAATTGTTTAATTTCACCTGAATATCA
TAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCATATTTATTCCATTGTTTTAGTCTGGCTATTTACAGTATAAAAAAAGC
ATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTATGCATATAGTAAGTATTACATTCTTAGAGTAGAGCAGAGTTTTTAGT
TAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATATTTCCAAAACTGTTACTGAGAATGGGTCAAGATCAGTGAGAAATCTT
TACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGTAATGCTTGGAATAAAAACTCTTAAGGCAACTCACTGATTTACTTCT
AGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAAGGTAATGTGTAAAATCAGTCTCGGCTGTCAGAATAACTTCTAAAAG
GTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCTTTCTGAAGTTCGTTAGTATAAATTACTTTTCTAGGATTATTAATAA
AAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGAGTGGTGAACCTTCTAGAGGAATATATGATTTATTCACAGTTCCTCA
AGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTACATCATGTTGTACATTAGAAATGGAGAGTTTAATAGCTCTTTAACT
GCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTGACTATTTTGCTGTGTTTTAAAAATGATTGAAATTTATCTTGCCATA
TCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAATATATTCGTAAAATAGGAGCACATTTAGTTGAGGTATACAAGGTAGG
ACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAAGTAATGGGTCTTGGAGTATAGATTTTTATTAGTAGCTTGAAAGAGC
TTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAATTTTTTAAGAAAAATATTTTTATCCTAGGGCCAAGTGTTGCCTGCC
ACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTTTTACCACCTAGTAACAGTCATTTCTGAAAATATGTTGGATAGAAAG
TCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTATTCCTTTTATGGCATCTATCTTGAAAGTAATCTTGTATTGGAGATT
GAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTACCTTTATGAAATATAGTTTTGTATAATAGCATAGATTTTCCTTCAAA
AAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATTTGAAAGCCTACTTTCTGAAGAAAATGGTGGGATTTTTTTTTATCAT
GATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTAAAACATTTGAAATACTACCATATTTGTGATTTATTGAGAATAAAAA
TCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAAGAAAACATGAATGAACTAGAAGATATTAAAAACATTTGACATTGGT
AAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATTTCAGAATTGATATTTTGAGAAAAATACATGTGAGTCATTTTTTCTG
TTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGAAAGGTAAAACAATTAGTCAAAATATTATTGCCATCATTCTACCTGT
GTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTACATTTCCATAAAGAAAACTCAAGTATTAATAAAAGAGACTTTACTGG
CTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCTAAGGGAGAGATTTGTGTGATAAAAGTATTGTATATAATAGATCAGC
GATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCCTAAGTTGCAAAATGTAATGATGAGCTTGGTGGAGAAGAATGAGTCG
TTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCACCTTGTTTGCATTCTTGGATAGCTTGTATATGTAGTAGTTTGATGAA
TAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGATCAAAAAAGGCAGATGAAATTACTTAATACTCAGTGTTTTGGAGAG
TATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAATATGCAGCATGCAATATATGCTTATATTTCATTTTAATTTCTGATAT
ATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTTGTCATTGTTCTCAAGTGCAATATAACAATGTAACCAAATCTAGATA
ATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAATATTTGTATTATTTTTGTTAGCAGGAAAGAGTGATTAAGTGAGGTTA
TTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAAATGAATTATTCTTTACCAGTTTTGAAACACTTTGAAATATCCTAAG
GTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTAATAACATAGAAAGTAAATATCTTTGTGGTCACCCACATTGGGTGAG
ACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGATTTGAGTTAGTGAAAACTGGTACAGTGTTCTGCTTGATTTACAACA

>33630_33630_2_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000265620_ITGAV_chr2_187540547_ENST00000374907_length(amino acids)=379AA_BP=
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDEKATKVQDIKNNLKEAIET
IVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQ
DLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTI
SVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRV

--------------------------------------------------------------
>33630_33630_3_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000265620_ITGAV_chr2_187540547_ENST00000433736_length(transcript)=2342nt_BP=1866nt
GGGCGGCGGCGGGGGCCCGGCCGAGGCAATAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCT
CGGCCCGGCGGCGGCCATCAGCCCCCTCGGCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTT
CCCGCCCGTCCGCGCGCCCCGCGGCCCGCGGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCG
CCCGGCGCTGCCCCGGCCCTCCCGGCCCGCGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCC
GCCATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAG
CTGCAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAG
ATGAGGATCCTGCATGTTAATGGGTTTAATGGAGATGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAA
ACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTG
ATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAA
CGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGAT
CAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTG
GGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAAC
ATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACC
ATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAA
TTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAG
TTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGT
GTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAG
CCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCT
TCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAG
GAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAA
TGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAATCAGAATCATTCCTAT
TCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACC
ACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTG
GCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCT
CATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATA
GATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCACAAAATGAGAATTATATTT

>33630_33630_3_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000265620_ITGAV_chr2_187540547_ENST00000433736_length(amino acids)=379AA_BP=
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDEKATKVQDIKNNLKEAIET
IVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQ
DLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTI
SVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRV

--------------------------------------------------------------
>33630_33630_4_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000306090_ITGAV_chr2_187540547_ENST00000261023_length(transcript)=5578nt_BP=1642nt
CAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCGGCCTCGGCTCGAGGGGCG
GGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCCCATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCG
CAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCT
GCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGACAGTGA
GAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGT
GGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTA
TGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTA
CTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAAT
CTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTG
CTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCA
GGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCT
CGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGA
GCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCA
CTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCA
CCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTA
CAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCA
GCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAA
AAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATC
AAAATAAAAATTAAATGTGAGCAAAGAAAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTA
TAAGAATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCC
TGTGTGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACG
GGTCCGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTT
AAGTTATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACT
GCTGATAGTGCTAATTGGCATTAACCACAAAATGAGAATTATATTTGTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAA
CATAGGGTGACTTGTGTTTTTAGGTATTTAAATAATAAAATTTCAAGGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGAT
TTACTACTTTATATAAAATAGTACCTCCTTCAGTTACTGTTTCTGATTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTG
TTGTTGTTTTAAAGCAGTCCAAATTTGGACCTTAGCAATCATGTCTTTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTA
CTTTTCAGAATACTAAAGACTTTATAACTGCATGAACTTGGATTTTTTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATA
CCATCCAAATTCTTGCTTTTAATAACAAAGGTACAATATTTTGTTTTAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATT
AAATCCACAATATTTTATTACATTTTTAACTTGTATAAATTTTAGGTCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAAT
CACAAATGGCTCTTTTGTGTAATTGTTTAATTTCACCTGAATATCATAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCAT
ATTTATTCCATTGTTTTAGTCTGGCTATTTACAGTATAAAAAAAGCATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTAT
GCATATAGTAAGTATTACATTCTTAGAGTAGAGCAGAGTTTTTAGTTAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATAT
TTCCAAAACTGTTACTGAGAATGGGTCAAGATCAGTGAGAAATCTTTACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGT
AATGCTTGGAATAAAAACTCTTAAGGCAACTCACTGATTTACTTCTAGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAA
GGTAATGTGTAAAATCAGTCTCGGCTGTCAGAATAACTTCTAAAAGGTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCT
TTCTGAAGTTCGTTAGTATAAATTACTTTTCTAGGATTATTAATAAAAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGA
GTGGTGAACCTTCTAGAGGAATATATGATTTATTCACAGTTCCTCAAGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTA
CATCATGTTGTACATTAGAAATGGAGAGTTTAATAGCTCTTTAACTGCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTG
ACTATTTTGCTGTGTTTTAAAAATGATTGAAATTTATCTTGCCATATCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAAT
ATATTCGTAAAATAGGAGCACATTTAGTTGAGGTATACAAGGTAGGACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAA
GTAATGGGTCTTGGAGTATAGATTTTTATTAGTAGCTTGAAAGAGCTTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAA
TTTTTTAAGAAAAATATTTTTATCCTAGGGCCAAGTGTTGCCTGCCACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTT
TTACCACCTAGTAACAGTCATTTCTGAAAATATGTTGGATAGAAAGTCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTA
TTCCTTTTATGGCATCTATCTTGAAAGTAATCTTGTATTGGAGATTGAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTAC
CTTTATGAAATATAGTTTTGTATAATAGCATAGATTTTCCTTCAAAAAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATT
TGAAAGCCTACTTTCTGAAGAAAATGGTGGGATTTTTTTTTATCATGATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTA
AAACATTTGAAATACTACCATATTTGTGATTTATTGAGAATAAAAATCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAA
GAAAACATGAATGAACTAGAAGATATTAAAAACATTTGACATTGGTAAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATT
TCAGAATTGATATTTTGAGAAAAATACATGTGAGTCATTTTTTCTGTTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGA
AAGGTAAAACAATTAGTCAAAATATTATTGCCATCATTCTACCTGTGTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTAC
ATTTCCATAAAGAAAACTCAAGTATTAATAAAAGAGACTTTACTGGCTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCT
AAGGGAGAGATTTGTGTGATAAAAGTATTGTATATAATAGATCAGCGATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCC
TAAGTTGCAAAATGTAATGATGAGCTTGGTGGAGAAGAATGAGTCGTTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCAC
CTTGTTTGCATTCTTGGATAGCTTGTATATGTAGTAGTTTGATGAATAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGA
TCAAAAAAGGCAGATGAAATTACTTAATACTCAGTGTTTTGGAGAGTATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAAT
ATGCAGCATGCAATATATGCTTATATTTCATTTTAATTTCTGATATATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTT
GTCATTGTTCTCAAGTGCAATATAACAATGTAACCAAATCTAGATAATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAAT
ATTTGTATTATTTTTGTTAGCAGGAAAGAGTGATTAAGTGAGGTTATTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAA
ATGAATTATTCTTTACCAGTTTTGAAACACTTTGAAATATCCTAAGGTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTA
ATAACATAGAAAGTAAATATCTTTGTGGTCACCCACATTGGGTGAGACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGA

>33630_33630_4_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000306090_ITGAV_chr2_187540547_ENST00000261023_length(amino acids)=433AA_BP=
MGVPFLEQLVLTKVHALNDVTAVVEHTADVLSVHSAGEMRVAVVTPISTGSADPQKLISNEVLGPGHAWVLSGLGSSILRSSVASKFWKV
VLNLRFPSKDFLSEQILLVEEQDHRDGAQPSVVPDALEEVQSLLQAVGLVVLPDDHVVAAAGHHEDDGSHIVEALDPLAAFIALATHVKH
VEVDFVHLELGLKDSRSQDTAAKQVLIARHIVSLLDHVDLVQEVLGTVNQLVLVGAFVAGTHSFILPQSLGMLIEFGREVKVRHVHHTQD
VVHSELVLGVGQLHGGHQVAHGGHNGFNRLFQVVFDVLHFGCLLTVSIKPINMQDPHLLHNGAFTRFSSTQQQQAVRGPVDLLVLLQLLL

--------------------------------------------------------------
>33630_33630_5_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000306090_ITGAV_chr2_187540547_ENST00000374907_length(transcript)=5574nt_BP=1642nt
CAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCGGCCTCGGCTCGAGGGGCG
GGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCCCATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCG
CAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCT
GCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGACAGTGA
GAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGT
GGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTA
TGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTA
CTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAAT
CTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTG
CTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCA
GGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCT
CGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGA
GCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCA
CTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCA
CCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTA
CAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCA
GCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAA
AAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATC
AAAATAAAAATTAAATGTGAGCAAAGAAAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTA
TAAGAATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCC
TGTGTGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACG
GGTCCGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTT
AAGTTATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACT
GCTGATAGTGCTAATTGGCATTAACCACAAAATGAGAATTATATTTGTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAA
CATAGGGTGACTTGTGTTTTTAGGTATTTAAATAATAAAATTTCAAGGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGAT
TTACTACTTTATATAAAATAGTACCTCCTTCAGTTACTGTTTCTGATTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTG
TTGTTGTTTTAAAGCAGTCCAAATTTGGACCTTAGCAATCATGTCTTTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTA
CTTTTCAGAATACTAAAGACTTTATAACTGCATGAACTTGGATTTTTTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATA
CCATCCAAATTCTTGCTTTTAATAACAAAGGTACAATATTTTGTTTTAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATT
AAATCCACAATATTTTATTACATTTTTAACTTGTATAAATTTTAGGTCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAAT
CACAAATGGCTCTTTTGTGTAATTGTTTAATTTCACCTGAATATCATAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCAT
ATTTATTCCATTGTTTTAGTCTGGCTATTTACAGTATAAAAAAAGCATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTAT
GCATATAGTAAGTATTACATTCTTAGAGTAGAGCAGAGTTTTTAGTTAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATAT
TTCCAAAACTGTTACTGAGAATGGGTCAAGATCAGTGAGAAATCTTTACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGT
AATGCTTGGAATAAAAACTCTTAAGGCAACTCACTGATTTACTTCTAGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAA
GGTAATGTGTAAAATCAGTCTCGGCTGTCAGAATAACTTCTAAAAGGTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCT
TTCTGAAGTTCGTTAGTATAAATTACTTTTCTAGGATTATTAATAAAAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGA
GTGGTGAACCTTCTAGAGGAATATATGATTTATTCACAGTTCCTCAAGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTA
CATCATGTTGTACATTAGAAATGGAGAGTTTAATAGCTCTTTAACTGCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTG
ACTATTTTGCTGTGTTTTAAAAATGATTGAAATTTATCTTGCCATATCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAAT
ATATTCGTAAAATAGGAGCACATTTAGTTGAGGTATACAAGGTAGGACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAA
GTAATGGGTCTTGGAGTATAGATTTTTATTAGTAGCTTGAAAGAGCTTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAA
TTTTTTAAGAAAAATATTTTTATCCTAGGGCCAAGTGTTGCCTGCCACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTT
TTACCACCTAGTAACAGTCATTTCTGAAAATATGTTGGATAGAAAGTCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTA
TTCCTTTTATGGCATCTATCTTGAAAGTAATCTTGTATTGGAGATTGAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTAC
CTTTATGAAATATAGTTTTGTATAATAGCATAGATTTTCCTTCAAAAAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATT
TGAAAGCCTACTTTCTGAAGAAAATGGTGGGATTTTTTTTTATCATGATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTA
AAACATTTGAAATACTACCATATTTGTGATTTATTGAGAATAAAAATCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAA
GAAAACATGAATGAACTAGAAGATATTAAAAACATTTGACATTGGTAAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATT
TCAGAATTGATATTTTGAGAAAAATACATGTGAGTCATTTTTTCTGTTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGA
AAGGTAAAACAATTAGTCAAAATATTATTGCCATCATTCTACCTGTGTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTAC
ATTTCCATAAAGAAAACTCAAGTATTAATAAAAGAGACTTTACTGGCTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCT
AAGGGAGAGATTTGTGTGATAAAAGTATTGTATATAATAGATCAGCGATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCC
TAAGTTGCAAAATGTAATGATGAGCTTGGTGGAGAAGAATGAGTCGTTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCAC
CTTGTTTGCATTCTTGGATAGCTTGTATATGTAGTAGTTTGATGAATAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGA
TCAAAAAAGGCAGATGAAATTACTTAATACTCAGTGTTTTGGAGAGTATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAAT
ATGCAGCATGCAATATATGCTTATATTTCATTTTAATTTCTGATATATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTT
GTCATTGTTCTCAAGTGCAATATAACAATGTAACCAAATCTAGATAATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAAT
ATTTGTATTATTTTTGTTAGCAGGAAAGAGTGATTAAGTGAGGTTATTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAA
ATGAATTATTCTTTACCAGTTTTGAAACACTTTGAAATATCCTAAGGTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTA
ATAACATAGAAAGTAAATATCTTTGTGGTCACCCACATTGGGTGAGACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGA

>33630_33630_5_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000306090_ITGAV_chr2_187540547_ENST00000374907_length(amino acids)=380AA_BP=
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKATKVQDIKNNLKEAIE
TIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSD
QDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRT
ISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRR

--------------------------------------------------------------
>33630_33630_6_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000306090_ITGAV_chr2_187540547_ENST00000433736_length(transcript)=2118nt_BP=1642nt
CAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCGGCCTCGGCTCGAGGGGCG
GGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCCCATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCG
CAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCT
GCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGACAGTGA
GAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGT
GGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTA
TGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTA
CTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAAT
CTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTG
CTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCA
GGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCT
CGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGA
GCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCA
CTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCA
CCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTA
CAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCA
GCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAA
AAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATC
AAAATAAAAATTAAATGTGAGCAAAGAAAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTA
TAAGAATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCC
TGTGTGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACG
GGTCCGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTT
AAGTTATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACT

>33630_33630_6_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000306090_ITGAV_chr2_187540547_ENST00000433736_length(amino acids)=380AA_BP=
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKATKVQDIKNNLKEAIE
TIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSD
QDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRT
ISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRR

--------------------------------------------------------------
>33630_33630_7_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000354359_ITGAV_chr2_187540547_ENST00000261023_length(transcript)=5911nt_BP=1975nt
TCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCAA
TAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCG
GCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCGC
GGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCCG
CGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGAC
CGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGC
CACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAA
TGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCAGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAA
CCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGT
GGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGG
AGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGC
TGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAA
CTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGT
GGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAA
CAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGAT
TGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAA
GTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGA
CACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAA
CCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATT
AACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTA
AGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAA
ATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGA
AAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCAC
CAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCT
AGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGA
AAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAG
AATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCA
CAAAATGAGAATTATATTTGTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAACATAGGGTGACTTGTGTTTTTAGGTAT
TTAAATAATAAAATTTCAAGGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGATTTACTACTTTATATAAAATAGTACCTC
CTTCAGTTACTGTTTCTGATTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTTTAAAGCAGTCCAAATTTG
GACCTTAGCAATCATGTCTTTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTACTTTTCAGAATACTAAAGACTTTATAA
CTGCATGAACTTGGATTTTTTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATACCATCCAAATTCTTGCTTTTAATAACA
AAGGTACAATATTTTGTTTTAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATTAAATCCACAATATTTTATTACATTTTT
AACTTGTATAAATTTTAGGTCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAATCACAAATGGCTCTTTTGTGTAATTGTT
TAATTTCACCTGAATATCATAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCATATTTATTCCATTGTTTTAGTCTGGCTA
TTTACAGTATAAAAAAAGCATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTATGCATATAGTAAGTATTACATTCTTAGA
GTAGAGCAGAGTTTTTAGTTAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATATTTCCAAAACTGTTACTGAGAATGGGTC
AAGATCAGTGAGAAATCTTTACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGTAATGCTTGGAATAAAAACTCTTAAGGC
AACTCACTGATTTACTTCTAGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAAGGTAATGTGTAAAATCAGTCTCGGCTG
TCAGAATAACTTCTAAAAGGTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCTTTCTGAAGTTCGTTAGTATAAATTACT
TTTCTAGGATTATTAATAAAAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGAGTGGTGAACCTTCTAGAGGAATATATG
ATTTATTCACAGTTCCTCAAGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTACATCATGTTGTACATTAGAAATGGAGA
GTTTAATAGCTCTTTAACTGCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTGACTATTTTGCTGTGTTTTAAAAATGAT
TGAAATTTATCTTGCCATATCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAATATATTCGTAAAATAGGAGCACATTTAG
TTGAGGTATACAAGGTAGGACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAAGTAATGGGTCTTGGAGTATAGATTTTT
ATTAGTAGCTTGAAAGAGCTTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAATTTTTTAAGAAAAATATTTTTATCCTA
GGGCCAAGTGTTGCCTGCCACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTTTTACCACCTAGTAACAGTCATTTCTGA
AAATATGTTGGATAGAAAGTCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTATTCCTTTTATGGCATCTATCTTGAAAG
TAATCTTGTATTGGAGATTGAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTACCTTTATGAAATATAGTTTTGTATAATA
GCATAGATTTTCCTTCAAAAAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATTTGAAAGCCTACTTTCTGAAGAAAATGG
TGGGATTTTTTTTTATCATGATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTAAAACATTTGAAATACTACCATATTTGT
GATTTATTGAGAATAAAAATCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAAGAAAACATGAATGAACTAGAAGATATT
AAAAACATTTGACATTGGTAAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATTTCAGAATTGATATTTTGAGAAAAATAC
ATGTGAGTCATTTTTTCTGTTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGAAAGGTAAAACAATTAGTCAAAATATTA
TTGCCATCATTCTACCTGTGTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTACATTTCCATAAAGAAAACTCAAGTATTA
ATAAAAGAGACTTTACTGGCTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCTAAGGGAGAGATTTGTGTGATAAAAGTA
TTGTATATAATAGATCAGCGATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCCTAAGTTGCAAAATGTAATGATGAGCTT
GGTGGAGAAGAATGAGTCGTTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCACCTTGTTTGCATTCTTGGATAGCTTGTA
TATGTAGTAGTTTGATGAATAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGATCAAAAAAGGCAGATGAAATTACTTAA
TACTCAGTGTTTTGGAGAGTATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAATATGCAGCATGCAATATATGCTTATATT
TCATTTTAATTTCTGATATATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTTGTCATTGTTCTCAAGTGCAATATAACA
ATGTAACCAAATCTAGATAATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAATATTTGTATTATTTTTGTTAGCAGGAAA
GAGTGATTAAGTGAGGTTATTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAAATGAATTATTCTTTACCAGTTTTGAAA
CACTTTGAAATATCCTAAGGTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTAATAACATAGAAAGTAAATATCTTTGTG
GTCACCCACATTGGGTGAGACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGATTTGAGTTAGTGAAAACTGGTACAGTG

>33630_33630_7_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000354359_ITGAV_chr2_187540547_ENST00000261023_length(amino acids)=542AA_BP=
MGVPFLEQLVLTKVHALNDVTAVVEHTADVLSVHSAGEMRVAVVTPISTGSADPQKLISNEVLGPGHAWVLSGLGSSILRSSVASKFWKV
VLNLRFPSKDFLSEQILLVEEQDHRDGAQPSVVPDALEEVQSLLQAVGLVVLPDDHVVAAAGHHEDDGSHIVEALDPLAAFIALATHVKH
VEVDFVHLELGLKDSRSQDTAAKQVLIARHIVSLLDHVDLVQEVLGTVNQLVLVGAFVAGTHSFILPQSLGMLIEFGREVKVRHVHHTQD
VVHSELVLGVGQLHGGHQVAHGGHNGFNRLFQVVFDVLHFGCLLTAIAVAPCSLRVLFAALSIKPINMQDPHLLHNGAFTRFSSTQQQQA
VRGPVDLLVLLQLLLDLFVGLTLRLLLVALVLGLTVPEAAHGGGGGGGARPGCGGGGRGRPHAGREGRGSAGRAGRARARLLGKERAGRT
AGRGPRGARTGGKGRVSVGPRGARSSPPLEPRPRGLMAAAGPRRTRAGAAGAAAAAAAAAALIASAGPPPPPRAKSAAAGGGRRGEEEAA

--------------------------------------------------------------
>33630_33630_8_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000354359_ITGAV_chr2_187540547_ENST00000374907_length(transcript)=5907nt_BP=1975nt
TCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCAA
TAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCG
GCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCGC
GGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCCG
CGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGAC
CGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGC
CACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAA
TGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCAGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAA
CCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGT
GGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGG
AGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGC
TGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAA
CTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGT
GGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAA
CAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGAT
TGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAA
GTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGA
CACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAA
CCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATT
AACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTA
AGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAA
ATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGA
AAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCAC
CAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCT
AGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGA
AAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAG
AATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCA
CAAAATGAGAATTATATTTGTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAACATAGGGTGACTTGTGTTTTTAGGTAT
TTAAATAATAAAATTTCAAGGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGATTTACTACTTTATATAAAATAGTACCTC
CTTCAGTTACTGTTTCTGATTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTTTAAAGCAGTCCAAATTTG
GACCTTAGCAATCATGTCTTTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTACTTTTCAGAATACTAAAGACTTTATAA
CTGCATGAACTTGGATTTTTTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATACCATCCAAATTCTTGCTTTTAATAACA
AAGGTACAATATTTTGTTTTAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATTAAATCCACAATATTTTATTACATTTTT
AACTTGTATAAATTTTAGGTCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAATCACAAATGGCTCTTTTGTGTAATTGTT
TAATTTCACCTGAATATCATAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCATATTTATTCCATTGTTTTAGTCTGGCTA
TTTACAGTATAAAAAAAGCATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTATGCATATAGTAAGTATTACATTCTTAGA
GTAGAGCAGAGTTTTTAGTTAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATATTTCCAAAACTGTTACTGAGAATGGGTC
AAGATCAGTGAGAAATCTTTACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGTAATGCTTGGAATAAAAACTCTTAAGGC
AACTCACTGATTTACTTCTAGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAAGGTAATGTGTAAAATCAGTCTCGGCTG
TCAGAATAACTTCTAAAAGGTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCTTTCTGAAGTTCGTTAGTATAAATTACT
TTTCTAGGATTATTAATAAAAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGAGTGGTGAACCTTCTAGAGGAATATATG
ATTTATTCACAGTTCCTCAAGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTACATCATGTTGTACATTAGAAATGGAGA
GTTTAATAGCTCTTTAACTGCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTGACTATTTTGCTGTGTTTTAAAAATGAT
TGAAATTTATCTTGCCATATCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAATATATTCGTAAAATAGGAGCACATTTAG
TTGAGGTATACAAGGTAGGACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAAGTAATGGGTCTTGGAGTATAGATTTTT
ATTAGTAGCTTGAAAGAGCTTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAATTTTTTAAGAAAAATATTTTTATCCTA
GGGCCAAGTGTTGCCTGCCACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTTTTACCACCTAGTAACAGTCATTTCTGA
AAATATGTTGGATAGAAAGTCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTATTCCTTTTATGGCATCTATCTTGAAAG
TAATCTTGTATTGGAGATTGAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTACCTTTATGAAATATAGTTTTGTATAATA
GCATAGATTTTCCTTCAAAAAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATTTGAAAGCCTACTTTCTGAAGAAAATGG
TGGGATTTTTTTTTATCATGATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTAAAACATTTGAAATACTACCATATTTGT
GATTTATTGAGAATAAAAATCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAAGAAAACATGAATGAACTAGAAGATATT
AAAAACATTTGACATTGGTAAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATTTCAGAATTGATATTTTGAGAAAAATAC
ATGTGAGTCATTTTTTCTGTTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGAAAGGTAAAACAATTAGTCAAAATATTA
TTGCCATCATTCTACCTGTGTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTACATTTCCATAAAGAAAACTCAAGTATTA
ATAAAAGAGACTTTACTGGCTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCTAAGGGAGAGATTTGTGTGATAAAAGTA
TTGTATATAATAGATCAGCGATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCCTAAGTTGCAAAATGTAATGATGAGCTT
GGTGGAGAAGAATGAGTCGTTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCACCTTGTTTGCATTCTTGGATAGCTTGTA
TATGTAGTAGTTTGATGAATAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGATCAAAAAAGGCAGATGAAATTACTTAA
TACTCAGTGTTTTGGAGAGTATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAATATGCAGCATGCAATATATGCTTATATT
TCATTTTAATTTCTGATATATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTTGTCATTGTTCTCAAGTGCAATATAACA
ATGTAACCAAATCTAGATAATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAATATTTGTATTATTTTTGTTAGCAGGAAA
GAGTGATTAAGTGAGGTTATTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAAATGAATTATTCTTTACCAGTTTTGAAA
CACTTTGAAATATCCTAAGGTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTAATAACATAGAAAGTAAATATCTTTGTG
GTCACCCACATTGGGTGAGACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGATTTGAGTTAGTGAAAACTGGTACAGTG

>33630_33630_8_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000354359_ITGAV_chr2_187540547_ENST00000374907_length(amino acids)=395AA_BP=
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGSEKA
TKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFL
DKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEA
LNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYC

--------------------------------------------------------------
>33630_33630_9_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000354359_ITGAV_chr2_187540547_ENST00000433736_length(transcript)=2451nt_BP=1975nt
TCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCAA
TAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCG
GCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCGC
GGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCCG
CGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGAC
CGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGC
CACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAA
TGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCAGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAA
CCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGT
GGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGG
AGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGC
TGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAA
CTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGT
GGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAA
CAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGAT
TGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAA
GTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGA
CACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAA
CCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATT
AACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTA
AGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAA
ATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGA
AAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCAC
CAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCT
AGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGA
AAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAG
AATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCA

>33630_33630_9_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000354359_ITGAV_chr2_187540547_ENST00000433736_length(amino acids)=395AA_BP=
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGSEKA
TKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFL
DKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEA
LNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYC

--------------------------------------------------------------
>33630_33630_10_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371085_ITGAV_chr2_187540547_ENST00000261023_length(transcript)=5908nt_BP=1972nt
TCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCAA
TAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCG
GCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCGC
GGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCCG
CGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGAC
CGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGC
CACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAA
TGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCT
GAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGA
CTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGT
GCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGA
CTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTT
CCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGC
CAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAA
CAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGA
GGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTA
CTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACAC
TGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCC
CCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAAC
AAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGG
CGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATG
AAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAA
TCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCACCAA
CTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCTAGC
AGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGAAAG
GGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAGAAT
TAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCACAA
AATGAGAATTATATTTGTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAACATAGGGTGACTTGTGTTTTTAGGTATTTA
AATAATAAAATTTCAAGGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGATTTACTACTTTATATAAAATAGTACCTCCTT
CAGTTACTGTTTCTGATTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTTTAAAGCAGTCCAAATTTGGAC
CTTAGCAATCATGTCTTTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTACTTTTCAGAATACTAAAGACTTTATAACTG
CATGAACTTGGATTTTTTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATACCATCCAAATTCTTGCTTTTAATAACAAAG
GTACAATATTTTGTTTTAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATTAAATCCACAATATTTTATTACATTTTTAAC
TTGTATAAATTTTAGGTCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAATCACAAATGGCTCTTTTGTGTAATTGTTTAA
TTTCACCTGAATATCATAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCATATTTATTCCATTGTTTTAGTCTGGCTATTT
ACAGTATAAAAAAAGCATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTATGCATATAGTAAGTATTACATTCTTAGAGTA
GAGCAGAGTTTTTAGTTAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATATTTCCAAAACTGTTACTGAGAATGGGTCAAG
ATCAGTGAGAAATCTTTACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGTAATGCTTGGAATAAAAACTCTTAAGGCAAC
TCACTGATTTACTTCTAGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAAGGTAATGTGTAAAATCAGTCTCGGCTGTCA
GAATAACTTCTAAAAGGTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCTTTCTGAAGTTCGTTAGTATAAATTACTTTT
CTAGGATTATTAATAAAAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGAGTGGTGAACCTTCTAGAGGAATATATGATT
TATTCACAGTTCCTCAAGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTACATCATGTTGTACATTAGAAATGGAGAGTT
TAATAGCTCTTTAACTGCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTGACTATTTTGCTGTGTTTTAAAAATGATTGA
AATTTATCTTGCCATATCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAATATATTCGTAAAATAGGAGCACATTTAGTTG
AGGTATACAAGGTAGGACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAAGTAATGGGTCTTGGAGTATAGATTTTTATT
AGTAGCTTGAAAGAGCTTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAATTTTTTAAGAAAAATATTTTTATCCTAGGG
CCAAGTGTTGCCTGCCACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTTTTACCACCTAGTAACAGTCATTTCTGAAAA
TATGTTGGATAGAAAGTCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTATTCCTTTTATGGCATCTATCTTGAAAGTAA
TCTTGTATTGGAGATTGAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTACCTTTATGAAATATAGTTTTGTATAATAGCA
TAGATTTTCCTTCAAAAAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATTTGAAAGCCTACTTTCTGAAGAAAATGGTGG
GATTTTTTTTTATCATGATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTAAAACATTTGAAATACTACCATATTTGTGAT
TTATTGAGAATAAAAATCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAAGAAAACATGAATGAACTAGAAGATATTAAA
AACATTTGACATTGGTAAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATTTCAGAATTGATATTTTGAGAAAAATACATG
TGAGTCATTTTTTCTGTTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGAAAGGTAAAACAATTAGTCAAAATATTATTG
CCATCATTCTACCTGTGTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTACATTTCCATAAAGAAAACTCAAGTATTAATA
AAAGAGACTTTACTGGCTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCTAAGGGAGAGATTTGTGTGATAAAAGTATTG
TATATAATAGATCAGCGATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCCTAAGTTGCAAAATGTAATGATGAGCTTGGT
GGAGAAGAATGAGTCGTTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCACCTTGTTTGCATTCTTGGATAGCTTGTATAT
GTAGTAGTTTGATGAATAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGATCAAAAAAGGCAGATGAAATTACTTAATAC
TCAGTGTTTTGGAGAGTATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAATATGCAGCATGCAATATATGCTTATATTTCA
TTTTAATTTCTGATATATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTTGTCATTGTTCTCAAGTGCAATATAACAATG
TAACCAAATCTAGATAATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAATATTTGTATTATTTTTGTTAGCAGGAAAGAG
TGATTAAGTGAGGTTATTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAAATGAATTATTCTTTACCAGTTTTGAAACAC
TTTGAAATATCCTAAGGTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTAATAACATAGAAAGTAAATATCTTTGTGGTC
ACCCACATTGGGTGAGACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGATTTGAGTTAGTGAAAACTGGTACAGTGTTC

>33630_33630_10_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371085_ITGAV_chr2_187540547_ENST00000261023_length(amino acids)=541AA_BP=
MGVPFLEQLVLTKVHALNDVTAVVEHTADVLSVHSAGEMRVAVVTPISTGSADPQKLISNEVLGPGHAWVLSGLGSSILRSSVASKFWKV
VLNLRFPSKDFLSEQILLVEEQDHRDGAQPSVVPDALEEVQSLLQAVGLVVLPDDHVVAAAGHHEDDGSHIVEALDPLAAFIALATHVKH
VEVDFVHLELGLKDSRSQDTAAKQVLIARHIVSLLDHVDLVQEVLGTVNQLVLVGAFVAGTHSFILPQSLGMLIEFGREVKVRHVHHTQD
VVHSELVLGVGQLHGGHQVAHGGHNGFNRLFQVVFDVLHFGCLLTIAVAPCSLRVLFAALSIKPINMQDPHLLHNGAFTRFSSTQQQQAV
RGPVDLLVLLQLLLDLFVGLTLRLLLVALVLGLTVPEAAHGGGGGGGARPGCGGGGRGRPHAGREGRGSAGRAGRARARLLGKERAGRTA
GRGPRGARTGGKGRVSVGPRGARSSPPLEPRPRGLMAAAGPRRTRAGAAGAAAAAAAAAALIASAGPPPPPRAKSAAAGGGRRGEEEAAA

--------------------------------------------------------------
>33630_33630_11_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371085_ITGAV_chr2_187540547_ENST00000374907_length(transcript)=5904nt_BP=1972nt
TCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCAA
TAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCG
GCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCGC
GGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCCG
CGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGAC
CGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGC
CACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAA
TGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCT
GAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGA
CTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGT
GCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGA
CTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTT
CCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGC
CAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAA
CAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGA
GGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTA
CTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACAC
TGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCC
CCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAAC
AAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGG
CGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATG
AAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAA
TCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCACCAA
CTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCTAGC
AGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGAAAG
GGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAGAAT
TAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCACAA
AATGAGAATTATATTTGTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAACATAGGGTGACTTGTGTTTTTAGGTATTTA
AATAATAAAATTTCAAGGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGATTTACTACTTTATATAAAATAGTACCTCCTT
CAGTTACTGTTTCTGATTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTTTAAAGCAGTCCAAATTTGGAC
CTTAGCAATCATGTCTTTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTACTTTTCAGAATACTAAAGACTTTATAACTG
CATGAACTTGGATTTTTTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATACCATCCAAATTCTTGCTTTTAATAACAAAG
GTACAATATTTTGTTTTAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATTAAATCCACAATATTTTATTACATTTTTAAC
TTGTATAAATTTTAGGTCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAATCACAAATGGCTCTTTTGTGTAATTGTTTAA
TTTCACCTGAATATCATAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCATATTTATTCCATTGTTTTAGTCTGGCTATTT
ACAGTATAAAAAAAGCATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTATGCATATAGTAAGTATTACATTCTTAGAGTA
GAGCAGAGTTTTTAGTTAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATATTTCCAAAACTGTTACTGAGAATGGGTCAAG
ATCAGTGAGAAATCTTTACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGTAATGCTTGGAATAAAAACTCTTAAGGCAAC
TCACTGATTTACTTCTAGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAAGGTAATGTGTAAAATCAGTCTCGGCTGTCA
GAATAACTTCTAAAAGGTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCTTTCTGAAGTTCGTTAGTATAAATTACTTTT
CTAGGATTATTAATAAAAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGAGTGGTGAACCTTCTAGAGGAATATATGATT
TATTCACAGTTCCTCAAGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTACATCATGTTGTACATTAGAAATGGAGAGTT
TAATAGCTCTTTAACTGCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTGACTATTTTGCTGTGTTTTAAAAATGATTGA
AATTTATCTTGCCATATCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAATATATTCGTAAAATAGGAGCACATTTAGTTG
AGGTATACAAGGTAGGACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAAGTAATGGGTCTTGGAGTATAGATTTTTATT
AGTAGCTTGAAAGAGCTTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAATTTTTTAAGAAAAATATTTTTATCCTAGGG
CCAAGTGTTGCCTGCCACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTTTTACCACCTAGTAACAGTCATTTCTGAAAA
TATGTTGGATAGAAAGTCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTATTCCTTTTATGGCATCTATCTTGAAAGTAA
TCTTGTATTGGAGATTGAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTACCTTTATGAAATATAGTTTTGTATAATAGCA
TAGATTTTCCTTCAAAAAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATTTGAAAGCCTACTTTCTGAAGAAAATGGTGG
GATTTTTTTTTATCATGATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTAAAACATTTGAAATACTACCATATTTGTGAT
TTATTGAGAATAAAAATCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAAGAAAACATGAATGAACTAGAAGATATTAAA
AACATTTGACATTGGTAAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATTTCAGAATTGATATTTTGAGAAAAATACATG
TGAGTCATTTTTTCTGTTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGAAAGGTAAAACAATTAGTCAAAATATTATTG
CCATCATTCTACCTGTGTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTACATTTCCATAAAGAAAACTCAAGTATTAATA
AAAGAGACTTTACTGGCTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCTAAGGGAGAGATTTGTGTGATAAAAGTATTG
TATATAATAGATCAGCGATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCCTAAGTTGCAAAATGTAATGATGAGCTTGGT
GGAGAAGAATGAGTCGTTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCACCTTGTTTGCATTCTTGGATAGCTTGTATAT
GTAGTAGTTTGATGAATAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGATCAAAAAAGGCAGATGAAATTACTTAATAC
TCAGTGTTTTGGAGAGTATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAATATGCAGCATGCAATATATGCTTATATTTCA
TTTTAATTTCTGATATATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTTGTCATTGTTCTCAAGTGCAATATAACAATG
TAACCAAATCTAGATAATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAATATTTGTATTATTTTTGTTAGCAGGAAAGAG
TGATTAAGTGAGGTTATTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAAATGAATTATTCTTTACCAGTTTTGAAACAC
TTTGAAATATCCTAAGGTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTAATAACATAGAAAGTAAATATCTTTGTGGTC
ACCCACATTGGGTGAGACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGATTTGAGTTAGTGAAAACTGGTACAGTGTTC

>33630_33630_11_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371085_ITGAV_chr2_187540547_ENST00000374907_length(amino acids)=394AA_BP=
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKAT
KVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLD
KIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEAL
NLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCY

--------------------------------------------------------------
>33630_33630_12_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371085_ITGAV_chr2_187540547_ENST00000433736_length(transcript)=2448nt_BP=1972nt
TCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCAA
TAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCG
GCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCGC
GGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCCG
CGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGAC
CGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGC
CACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAA
TGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCT
GAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGA
CTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGT
GCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGA
CTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTT
CCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGC
CAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAA
CAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGA
GGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTA
CTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACAC
TGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCC
CCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAAC
AAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGG
CGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATG
AAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAA
TCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCACCAA
CTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCTAGC
AGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGAAAG
GGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAGAAT
TAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCACAA

>33630_33630_12_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371085_ITGAV_chr2_187540547_ENST00000433736_length(amino acids)=394AA_BP=
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKAT
KVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLD
KIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEAL
NLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCY

--------------------------------------------------------------
>33630_33630_13_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371095_ITGAV_chr2_187540547_ENST00000261023_length(transcript)=5867nt_BP=1931nt
CTCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCA
ATAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTC
GGCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCG
CGGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCC
GCGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGA
CCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGG
CCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTA
ATGGAGACAGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACC
TGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCC
CTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTG
ACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCC
TGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCA
AGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGA
CCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACA
AGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGG
ATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTG
GAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCA
TTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTG
AAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCC
CCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTC
TCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGC
ATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTA
ATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGC
CAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACA
GGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAG
AAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGT
AAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCACAAAATGAGAATTATATTTGTCAACCTTCTCCTTATAAATAAGT
TCAGACATACATTTAATAACATAGGGTGACTTGTGTTTTTAGGTATTTAAATAATAAAATTTCAAGGGATAGTTTTTATTCAATGTATAT
AAGACAGGTAGTGCCTGATTTACTACTTTATATAAAATAGTACCTCCTTCAGTTACTGTTTCTGATTTAATGTACGGAACTTTATTTGTT
GTTGTTGTTGTTGTTGTTGTTGTTGTTTTAAAGCAGTCCAAATTTGGACCTTAGCAATCATGTCTTTTGTATAGGTACTTAATGTTAATA
CATATTACACTACAGTTTACTTTTCAGAATACTAAAGACTTTATAACTGCATGAACTTGGATTTTTTTAATCACTCATATGGTAGAATTT
TATAAACACATACATGATACCATCCAAATTCTTGCTTTTAATAACAAAGGTACAATATTTTGTTTTAGTATGAAAATCTGGTAGATCCTA
TTACACTTCTGTTTATATTAAATCCACAATATTTTATTACATTTTTAACTTGTATAAATTTTAGGTCAAATCCTTCAAGCCAACCTATAC
TAAAAATTAGTTCCATAATCACAAATGGCTCTTTTGTGTAATTGTTTAATTTCACCTGAATATCATAATGCTTAAAGCCATATGGAGTTG
GAAATTATTTCCAAAGCATATTTATTCCATTGTTTTAGTCTGGCTATTTACAGTATAAAAAAAGCATTTTTATTAAAATACTGTGTAGTT
CTTTGAGATAGTTGCTTATGCATATAGTAAGTATTACATTCTTAGAGTAGAGCAGAGTTTTTAGTTAGTATTAATTTATTTTCCTCCATT
CATGTACTTTTCCTTATATTTCCAAAACTGTTACTGAGAATGGGTCAAGATCAGTGAGAAATCTTTACAGTTGACAGGAACCTGGACCCC
TTACCCCAACTTTATGAGTAATGCTTGGAATAAAAACTCTTAAGGCAACTCACTGATTTACTTCTAGCAATAGCATGATGTTACAGGAAT
ATTACCTCTGTTTAAGCAAGGTAATGTGTAAAATCAGTCTCGGCTGTCAGAATAACTTCTAAAAGGTATTTTTATAAGCAGTTCAAGTTA
CTGAAAACCTTTTAAACCTTTCTGAAGTTCGTTAGTATAAATTACTTTTCTAGGATTATTAATAAAAGCCACATAGGTGGCAAGTTGTAG
TTTTATATGGCTCTGTAGAGTGGTGAACCTTCTAGAGGAATATATGATTTATTCACAGTTCCTCAAGGCCTGGGGATGATGATCAGTTAT
ACCTATTTTTGTGCAATTACATCATGTTGTACATTAGAAATGGAGAGTTTAATAGCTCTTTAACTGCTGTCCTCATTAGGTAATGATAAA
TATTTCCCTTAAATAATTGACTATTTTGCTGTGTTTTAAAAATGATTGAAATTTATCTTGCCATATCTCATAATTTCATGCACAAGTTGA
CTGAGCTAATCTTGAGAATATATTCGTAAAATAGGAGCACATTTAGTTGAGGTATACAAGGTAGGACTCTAGACAAAACCTTCTATTTTA
GCTTTAGTGAATTTCAAAAGTAATGGGTCTTGGAGTATAGATTTTTATTAGTAGCTTGAAAGAGCTTAATCATATGCAGTAAGTATTTTT
ATTACCAATAAATTTAAAATTTTTTAAGAAAAATATTTTTATCCTAGGGCCAAGTGTTGCCTGCCACCAATCAGTAAGTTAGTCTATAAC
AAATTTTACCCTAACAGTTTTACCACCTAGTAACAGTCATTTCTGAAAATATGTTGGATAGAAAGTCACTCTTTGGCAAAAGTGTTAGAA
TTTGCTTTTGTGCCATCTATTCCTTTTATGGCATCTATCTTGAAAGTAATCTTGTATTGGAGATTGAAAGATGCTGTAATTTAGAAATTA
ACATGATATCTTAAATTACCTTTATGAAATATAGTTTTGTATAATAGCATAGATTTTCCTTCAAAAAATGAACATTTATATATCTACAAA
AATATGGAGAAGAGTAATTTGAAAGCCTACTTTCTGAAGAAAATGGTGGGATTTTTTTTTATCATGATTAAATATCAAAAAATTGCCCTA
TGAAAACTTTAAATCTCTAAAACATTTGAAATACTACCATATTTGTGATTTATTGAGAATAAAAATCCATTTTGAAATGTAAAATTTTTA
TGATCTGATTCAGTTTTAAGAAAACATGAATGAACTAGAAGATATTAAAAACATTTGACATTGGTAAGAAATATTGATACTGATATTGAT
TTTTATATAGGTATTTATTTCAGAATTGATATTTTGAGAAAAATACATGTGAGTCATTTTTTCTGTTTCTCTTTTCTCTTAACGATTATC
ACTGTAATTCTGAATCTGAAAGGTAAAACAATTAGTCAAAATATTATTGCCATCATTCTACCTGTGTTATGAAACTACTTATTCATAGTT
AATTCTCATTAACACTTACATTTCCATAAAGAAAACTCAAGTATTAATAAAAGAGACTTTACTGGCTTAAGAGGGCTGTGAAAGATTTTT
GATAGTGAATCATGACCCTAAGGGAGAGATTTGTGTGATAAAAGTATTGTATATAATAGATCAGCGATTTTTGTAAGGCAAACAGAATTT
GTAAGTTGGCAGATCTTCCTAAGTTGCAAAATGTAATGATGAGCTTGGTGGAGAAGAATGAGTCGTTCTTGGAATACCTATGTGCAGCCA
CTACCCATCTCAATGTCACCTTGTTTGCATTCTTGGATAGCTTGTATATGTAGTAGTTTGATGAATAATTTAAAGAAAAACACCTAAAAT
TTGAAAAATGATTGTAGGATCAAAAAAGGCAGATGAAATTACTTAATACTCAGTGTTTTGGAGAGTATTCCTTTTAGTTTGTTGGTTGGC
TGGTTTGAACGATAGAAATATGCAGCATGCAATATATGCTTATATTTCATTTTAATTTCTGATATATAATGAACTTCTTGGGAGAGGTAC
TGAATCTTTGATGTTTTTTGTCATTGTTCTCAAGTGCAATATAACAATGTAACCAAATCTAGATAATTTCAAAGTTGTCATTAATTTAGT
AAGCCTAATATAAACAAATATTTGTATTATTTTTGTTAGCAGGAAAGAGTGATTAAGTGAGGTTATTTACCCCTAAATGGTCCATTCTGC
ATTGTATTTCAGGCTGGAAATGAATTATTCTTTACCAGTTTTGAAACACTTTGAAATATCCTAAGGTAACTTGGAAGCTGTGTAGTATAT
CAAATTAATTTGCTACCTAATAACATAGAAAGTAAATATCTTTGTGGTCACCCACATTGGGTGAGACAGAAAATGAATCTGTTCTAAAAT
TTGTAATTTGCTAACTTGATTTGAGTTAGTGAAAACTGGTACAGTGTTCTGCTTGATTTACAACATGTAACTTGTGACTGTACAATAAAC

>33630_33630_13_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371095_ITGAV_chr2_187540547_ENST00000261023_length(amino acids)=527AA_BP=
MGVPFLEQLVLTKVHALNDVTAVVEHTADVLSVHSAGEMRVAVVTPISTGSADPQKLISNEVLGPGHAWVLSGLGSSILRSSVASKFWKV
VLNLRFPSKDFLSEQILLVEEQDHRDGAQPSVVPDALEEVQSLLQAVGLVVLPDDHVVAAAGHHEDDGSHIVEALDPLAAFIALATHVKH
VEVDFVHLELGLKDSRSQDTAAKQVLIARHIVSLLDHVDLVQEVLGTVNQLVLVGAFVAGTHSFILPQSLGMLIEFGREVKVRHVHHTQD
VVHSELVLGVGQLHGGHQVAHGGHNGFNRLFQVVFDVLHFGCLLTVSIKPINMQDPHLLHNGAFTRFSSTQQQQAVRGPVDLLVLLQLLL
DLFVGLTLRLLLVALVLGLTVPEAAHGGGGGGGARPGCGGGGRGRPHAGREGRGSAGRAGRARARLLGKERAGRTAGRGPRGARTGGKGR

--------------------------------------------------------------
>33630_33630_14_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371095_ITGAV_chr2_187540547_ENST00000374907_length(transcript)=5863nt_BP=1931nt
CTCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCA
ATAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTC
GGCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCG
CGGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCC
GCGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGA
CCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGG
CCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTA
ATGGAGACAGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACC
TGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCC
CTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTG
ACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCC
TGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCA
AGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGA
CCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACA
AGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGG
ATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTG
GAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCA
TTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTG
AAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCC
CCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTC
TCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGC
ATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTA
ATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGC
CAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACA
GGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAG
AAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGT
AAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCACAAAATGAGAATTATATTTGTCAACCTTCTCCTTATAAATAAGT
TCAGACATACATTTAATAACATAGGGTGACTTGTGTTTTTAGGTATTTAAATAATAAAATTTCAAGGGATAGTTTTTATTCAATGTATAT
AAGACAGGTAGTGCCTGATTTACTACTTTATATAAAATAGTACCTCCTTCAGTTACTGTTTCTGATTTAATGTACGGAACTTTATTTGTT
GTTGTTGTTGTTGTTGTTGTTGTTGTTTTAAAGCAGTCCAAATTTGGACCTTAGCAATCATGTCTTTTGTATAGGTACTTAATGTTAATA
CATATTACACTACAGTTTACTTTTCAGAATACTAAAGACTTTATAACTGCATGAACTTGGATTTTTTTAATCACTCATATGGTAGAATTT
TATAAACACATACATGATACCATCCAAATTCTTGCTTTTAATAACAAAGGTACAATATTTTGTTTTAGTATGAAAATCTGGTAGATCCTA
TTACACTTCTGTTTATATTAAATCCACAATATTTTATTACATTTTTAACTTGTATAAATTTTAGGTCAAATCCTTCAAGCCAACCTATAC
TAAAAATTAGTTCCATAATCACAAATGGCTCTTTTGTGTAATTGTTTAATTTCACCTGAATATCATAATGCTTAAAGCCATATGGAGTTG
GAAATTATTTCCAAAGCATATTTATTCCATTGTTTTAGTCTGGCTATTTACAGTATAAAAAAAGCATTTTTATTAAAATACTGTGTAGTT
CTTTGAGATAGTTGCTTATGCATATAGTAAGTATTACATTCTTAGAGTAGAGCAGAGTTTTTAGTTAGTATTAATTTATTTTCCTCCATT
CATGTACTTTTCCTTATATTTCCAAAACTGTTACTGAGAATGGGTCAAGATCAGTGAGAAATCTTTACAGTTGACAGGAACCTGGACCCC
TTACCCCAACTTTATGAGTAATGCTTGGAATAAAAACTCTTAAGGCAACTCACTGATTTACTTCTAGCAATAGCATGATGTTACAGGAAT
ATTACCTCTGTTTAAGCAAGGTAATGTGTAAAATCAGTCTCGGCTGTCAGAATAACTTCTAAAAGGTATTTTTATAAGCAGTTCAAGTTA
CTGAAAACCTTTTAAACCTTTCTGAAGTTCGTTAGTATAAATTACTTTTCTAGGATTATTAATAAAAGCCACATAGGTGGCAAGTTGTAG
TTTTATATGGCTCTGTAGAGTGGTGAACCTTCTAGAGGAATATATGATTTATTCACAGTTCCTCAAGGCCTGGGGATGATGATCAGTTAT
ACCTATTTTTGTGCAATTACATCATGTTGTACATTAGAAATGGAGAGTTTAATAGCTCTTTAACTGCTGTCCTCATTAGGTAATGATAAA
TATTTCCCTTAAATAATTGACTATTTTGCTGTGTTTTAAAAATGATTGAAATTTATCTTGCCATATCTCATAATTTCATGCACAAGTTGA
CTGAGCTAATCTTGAGAATATATTCGTAAAATAGGAGCACATTTAGTTGAGGTATACAAGGTAGGACTCTAGACAAAACCTTCTATTTTA
GCTTTAGTGAATTTCAAAAGTAATGGGTCTTGGAGTATAGATTTTTATTAGTAGCTTGAAAGAGCTTAATCATATGCAGTAAGTATTTTT
ATTACCAATAAATTTAAAATTTTTTAAGAAAAATATTTTTATCCTAGGGCCAAGTGTTGCCTGCCACCAATCAGTAAGTTAGTCTATAAC
AAATTTTACCCTAACAGTTTTACCACCTAGTAACAGTCATTTCTGAAAATATGTTGGATAGAAAGTCACTCTTTGGCAAAAGTGTTAGAA
TTTGCTTTTGTGCCATCTATTCCTTTTATGGCATCTATCTTGAAAGTAATCTTGTATTGGAGATTGAAAGATGCTGTAATTTAGAAATTA
ACATGATATCTTAAATTACCTTTATGAAATATAGTTTTGTATAATAGCATAGATTTTCCTTCAAAAAATGAACATTTATATATCTACAAA
AATATGGAGAAGAGTAATTTGAAAGCCTACTTTCTGAAGAAAATGGTGGGATTTTTTTTTATCATGATTAAATATCAAAAAATTGCCCTA
TGAAAACTTTAAATCTCTAAAACATTTGAAATACTACCATATTTGTGATTTATTGAGAATAAAAATCCATTTTGAAATGTAAAATTTTTA
TGATCTGATTCAGTTTTAAGAAAACATGAATGAACTAGAAGATATTAAAAACATTTGACATTGGTAAGAAATATTGATACTGATATTGAT
TTTTATATAGGTATTTATTTCAGAATTGATATTTTGAGAAAAATACATGTGAGTCATTTTTTCTGTTTCTCTTTTCTCTTAACGATTATC
ACTGTAATTCTGAATCTGAAAGGTAAAACAATTAGTCAAAATATTATTGCCATCATTCTACCTGTGTTATGAAACTACTTATTCATAGTT
AATTCTCATTAACACTTACATTTCCATAAAGAAAACTCAAGTATTAATAAAAGAGACTTTACTGGCTTAAGAGGGCTGTGAAAGATTTTT
GATAGTGAATCATGACCCTAAGGGAGAGATTTGTGTGATAAAAGTATTGTATATAATAGATCAGCGATTTTTGTAAGGCAAACAGAATTT
GTAAGTTGGCAGATCTTCCTAAGTTGCAAAATGTAATGATGAGCTTGGTGGAGAAGAATGAGTCGTTCTTGGAATACCTATGTGCAGCCA
CTACCCATCTCAATGTCACCTTGTTTGCATTCTTGGATAGCTTGTATATGTAGTAGTTTGATGAATAATTTAAAGAAAAACACCTAAAAT
TTGAAAAATGATTGTAGGATCAAAAAAGGCAGATGAAATTACTTAATACTCAGTGTTTTGGAGAGTATTCCTTTTAGTTTGTTGGTTGGC
TGGTTTGAACGATAGAAATATGCAGCATGCAATATATGCTTATATTTCATTTTAATTTCTGATATATAATGAACTTCTTGGGAGAGGTAC
TGAATCTTTGATGTTTTTTGTCATTGTTCTCAAGTGCAATATAACAATGTAACCAAATCTAGATAATTTCAAAGTTGTCATTAATTTAGT
AAGCCTAATATAAACAAATATTTGTATTATTTTTGTTAGCAGGAAAGAGTGATTAAGTGAGGTTATTTACCCCTAAATGGTCCATTCTGC
ATTGTATTTCAGGCTGGAAATGAATTATTCTTTACCAGTTTTGAAACACTTTGAAATATCCTAAGGTAACTTGGAAGCTGTGTAGTATAT
CAAATTAATTTGCTACCTAATAACATAGAAAGTAAATATCTTTGTGGTCACCCACATTGGGTGAGACAGAAAATGAATCTGTTCTAAAAT
TTGTAATTTGCTAACTTGATTTGAGTTAGTGAAAACTGGTACAGTGTTCTGCTTGATTTACAACATGTAACTTGTGACTGTACAATAAAC

>33630_33630_14_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371095_ITGAV_chr2_187540547_ENST00000374907_length(amino acids)=380AA_BP=
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKATKVQDIKNNLKEAIE
TIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSD
QDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRT
ISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRR

--------------------------------------------------------------
>33630_33630_15_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371095_ITGAV_chr2_187540547_ENST00000433736_length(transcript)=2407nt_BP=1931nt
CTCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCA
ATAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTC
GGCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCG
CGGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCC
GCGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGA
CCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGG
CCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTA
ATGGAGACAGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACC
TGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCC
CTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTG
ACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCC
TGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCA
AGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGA
CCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACA
AGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGG
ATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTG
GAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCA
TTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTG
AAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCC
CCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTC
TCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGC
ATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTA
ATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGC
CAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACA
GGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAG
AAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGT

>33630_33630_15_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371095_ITGAV_chr2_187540547_ENST00000433736_length(amino acids)=380AA_BP=
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKATKVQDIKNNLKEAIE
TIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSD
QDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRT
ISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRR

--------------------------------------------------------------
>33630_33630_16_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371100_ITGAV_chr2_187540547_ENST00000261023_length(transcript)=7965nt_BP=4029nt
AAAGACTCCAAATCAGTCAGGGAGAGGAGTGGAAGGAGCCAAAACGTCCCTGCGAGGCCTGCGCTCACCAGCCCCCTTACCCAAAGTCCC
GGGCCCCTGGCGCCAGGAGCAGGCTCCTGGAGCCGGAGCCAGCTCGGCACTGGAACCGGCGTCCTCTGGTGGCAGAGAGAGAGCGCTACT
GGCGATTTTCGGACCGAATCGGCACGCTCGTCAGATCCAAGCAGGCGGGACTGGCCTGGAGCAAAAAGAAAGAGAGAGGAGGGCGTAAGG
ATAGACCAAGGAAGAGGGGCTGGGGGGCAGCCTGGGGGCATGAAAAGTGGCCAGGAAGGAGCCAAGACTCCACCAGCAACAATTGAGTTG
CTTCAGCCTCAGTCTAGGGTTCCTTCCAGGCCTTGAACCCCCCAACCTCACAAGGGTTGGAAAGTGAGGCCGGTGAACTTTCCAGCTGGT
ACTTTGATTTTAAAATAATAATAATAATTTTTTCACCCTAGTTCGGTTGGGTGCTCCATCTTACGGAGCCCCAAACTTATTTTGAGAGGC
CGCCACCGTGTTATGGGCGTGCGCAACTGCCTCTACGGCAATAATATGTCAGGACAACGCGATATCCCCCCTGAAATCGGGGAACAGCCC
GAGCAACCACCTTTGGAGGCCCCAGGGGCAGCTGCCCCCGGTGCTGGGCCTAGCCCAGCCGAAGAGATGGAGACCGAACCGCCTCACAAC
GAGCCCATCCCCGTCGAGAATGATGGCGAGGCCTGTGGACCCCCAGAGGTCTCCAGACCCAACTTTCAGGTCCTCAACCCGGCATTCAGG
GAAGCTGGAGCCCATGGAAGCTACAGCCCACCTCCTGAGGAAGCAATGCCCTTCGAGGCTGAACAGCCCAGCTTGGGAGGCTTCTGGCCT
ACACTGGAGCAGCCTGGATTCCCCAGTGGGGTCCATGCAGGCCTTGAGGCCTTCGGCCCAGCACTCATGGAGCCCGGAGCCTTCAGTGGT
GCCAGACCAGGCCTGGGAGGATACAGCCCTCCACCAGAAGAAGCTATGCCCTTTGAGTTTGACCAGCCTGCCCAGAGAGGCTGCAGTCAA
CTTCTCTTACAGGTCCCAGACCTTGCTCCAGGAGGCCCAGGTGCTGCAGGGGTCCCCGGAGCTCCTCCCGAGGAGCCCCAAGCCCTCAGG
CCTGCAAAGGCTGGCTCCAGAGGAGGCTACAGCCCTCCCCCTGAGGAGACTATGCCATTTGAGCTTGATGGAGAAGGATTTGGGGACGAC
AGCCCACCCCCGGGGCTTTCCCGAGTTATCGCACAAGTCGACGGCAGCAGCCAGTTCGCGGCAGTCGCGGCCTCGAGTGCGGTCCGCCTC
ACTCCCGCCGCGAACGCGCCTCCCCTCTGGGTCCCAGGCGCCATCGGCAGCCCATCCCAAGAGGCTGTCAGACCTCCTTCTAACTTCACG
GGCAGCAGCCCCTGGATGGAGATCTCCGGACCCCCGTTCGAGATTGGCAGCGCCCCCGCTGGGGTCGACGACACTCCCGTCAACATGGAC
AGCCCCCCAATCGCGCTTGACGGCCCGCCCATCAAGGTCTCCGGAGCCCCAGATAAGAGAGAGCGAGCAGAGAGACCCCCAGTTGAGGAG
GAAGCAGCAGAGATGGAAGGAGCCGCTGATGCCGCGGAGGGAGGAAAAGTACCCTCTCCGGGGTACGGATCCCCTGCCGCCGGGGCAGCC
TCAGCGGATACCGCTGCCAGGGCAGCCCCTGCAGCCCCAGCCGATCCTGACTCCGGGGCAACCCCAGAAGATCCCGACTCCGGGACAGCA
CCAGCCGATCCTGACTCCGGGGCATTCGCAGCCGATCCCGACTCCGGGGCAGCCCCTGCCGCCCCAGCCGATCCCGACTCCGGGGCGGCC
CCTGACGCCCCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCAGCCGATCCAGATGCCGGGGCGGCCCCTGAGGCTCCCGCCGCC
CCTGCGGCTGCTGAGACCCGGGCAGCCCATGTCGCCCCAGCTGCGCCAGACGCAGGGGCTCCCACTGCCCCAGCCGCTTCTGCCACCCGG
GCAGCCCAAGTCCGCCGGGCGGCCTCTGCAGCCCCTGCCTCCGGGGCCAGACGCAAGATCCATCTCAGACCCCCCAGCCCCGAGATCCAG
GCTGCCGATCCGCCTACTCCGCGGCCTACTCGCGCGTCTGCCTGGCGGGGCAAGTCCGAGAGCAGCCGCGGCCGCCGCGTGTACTACGAT
GAAGGGGTGGCCAGCAGCGACGATGACTCCAGCGGAGACGAGTCCGACGATGGGACCTCCGGATGCCTCCGCTGGTTTCAGCATCGGCGA
AATCGCCGCCGCCGAAAGCCCCAGCGCAACTTACTCCGCAACTTTCTCGTGCAAGCCTTCGGGGGCTGCTTCGGTCGATCTGAGAGTCCC
CAGCCCAAAGCCTCGCGCTCTCTCAAGGTCAAGAAGGTACCCCTGGCGGAGAAGCGCAGACAGATGCGCAAAGAAGCCCTGGAGAAGCGG
GCCCAGAAGCGCGCAGAGAAGAAACGCAGTAAGCTCATCGACAAACAACTCCAGGACGAAAAGATGGGCTACATGTGTACGCACCGCCTG
CTGCTTCTAGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGC
GAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATT
GAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGT
GTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTAC
GAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGC
GATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGAC
GTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTAC
AACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGC
ACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCA
GAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGAT
GAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGC
CGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTA
AAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTC
CCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAA
AAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAAC
AAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAATCAGAATCATTCC
TATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCACCAACTCCACATTGGTT
ACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTA
CTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAA
CCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAGAATTAGCAACTTTATT
ATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCACAAAATGAGAATTATA
TTTGTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAACATAGGGTGACTTGTGTTTTTAGGTATTTAAATAATAAAATTT
CAAGGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGATTTACTACTTTATATAAAATAGTACCTCCTTCAGTTACTGTTTC
TGATTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTTTAAAGCAGTCCAAATTTGGACCTTAGCAATCATG
TCTTTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTACTTTTCAGAATACTAAAGACTTTATAACTGCATGAACTTGGAT
TTTTTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATACCATCCAAATTCTTGCTTTTAATAACAAAGGTACAATATTTTG
TTTTAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATTAAATCCACAATATTTTATTACATTTTTAACTTGTATAAATTTT
AGGTCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAATCACAAATGGCTCTTTTGTGTAATTGTTTAATTTCACCTGAATA
TCATAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCATATTTATTCCATTGTTTTAGTCTGGCTATTTACAGTATAAAAAA
AGCATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTATGCATATAGTAAGTATTACATTCTTAGAGTAGAGCAGAGTTTTT
AGTTAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATATTTCCAAAACTGTTACTGAGAATGGGTCAAGATCAGTGAGAAAT
CTTTACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGTAATGCTTGGAATAAAAACTCTTAAGGCAACTCACTGATTTACT
TCTAGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAAGGTAATGTGTAAAATCAGTCTCGGCTGTCAGAATAACTTCTAA
AAGGTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCTTTCTGAAGTTCGTTAGTATAAATTACTTTTCTAGGATTATTAA
TAAAAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGAGTGGTGAACCTTCTAGAGGAATATATGATTTATTCACAGTTCC
TCAAGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTACATCATGTTGTACATTAGAAATGGAGAGTTTAATAGCTCTTTA
ACTGCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTGACTATTTTGCTGTGTTTTAAAAATGATTGAAATTTATCTTGCC
ATATCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAATATATTCGTAAAATAGGAGCACATTTAGTTGAGGTATACAAGGT
AGGACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAAGTAATGGGTCTTGGAGTATAGATTTTTATTAGTAGCTTGAAAG
AGCTTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAATTTTTTAAGAAAAATATTTTTATCCTAGGGCCAAGTGTTGCCT
GCCACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTTTTACCACCTAGTAACAGTCATTTCTGAAAATATGTTGGATAGA
AAGTCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTATTCCTTTTATGGCATCTATCTTGAAAGTAATCTTGTATTGGAG
ATTGAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTACCTTTATGAAATATAGTTTTGTATAATAGCATAGATTTTCCTTC
AAAAAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATTTGAAAGCCTACTTTCTGAAGAAAATGGTGGGATTTTTTTTTAT
CATGATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTAAAACATTTGAAATACTACCATATTTGTGATTTATTGAGAATAA
AAATCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAAGAAAACATGAATGAACTAGAAGATATTAAAAACATTTGACATT
GGTAAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATTTCAGAATTGATATTTTGAGAAAAATACATGTGAGTCATTTTTT
CTGTTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGAAAGGTAAAACAATTAGTCAAAATATTATTGCCATCATTCTACC
TGTGTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTACATTTCCATAAAGAAAACTCAAGTATTAATAAAAGAGACTTTAC
TGGCTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCTAAGGGAGAGATTTGTGTGATAAAAGTATTGTATATAATAGATC
AGCGATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCCTAAGTTGCAAAATGTAATGATGAGCTTGGTGGAGAAGAATGAG
TCGTTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCACCTTGTTTGCATTCTTGGATAGCTTGTATATGTAGTAGTTTGAT
GAATAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGATCAAAAAAGGCAGATGAAATTACTTAATACTCAGTGTTTTGGA
GAGTATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAATATGCAGCATGCAATATATGCTTATATTTCATTTTAATTTCTGA
TATATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTTGTCATTGTTCTCAAGTGCAATATAACAATGTAACCAAATCTAG
ATAATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAATATTTGTATTATTTTTGTTAGCAGGAAAGAGTGATTAAGTGAGG
TTATTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAAATGAATTATTCTTTACCAGTTTTGAAACACTTTGAAATATCCT
AAGGTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTAATAACATAGAAAGTAAATATCTTTGTGGTCACCCACATTGGGT
GAGACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGATTTGAGTTAGTGAAAACTGGTACAGTGTTCTGCTTGATTTACA

>33630_33630_16_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371100_ITGAV_chr2_187540547_ENST00000261023_length(amino acids)=1044AA_BP=
MRGRHRVMGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNP
AFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRG
CSQLLLQVPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSA
VRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPP
VEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDS
GAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSP
EIQAADPPTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRS
ESPQPKASRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNG
EGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR
ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS
SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYF

--------------------------------------------------------------
>33630_33630_17_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371100_ITGAV_chr2_187540547_ENST00000374907_length(transcript)=7961nt_BP=4029nt
AAAGACTCCAAATCAGTCAGGGAGAGGAGTGGAAGGAGCCAAAACGTCCCTGCGAGGCCTGCGCTCACCAGCCCCCTTACCCAAAGTCCC
GGGCCCCTGGCGCCAGGAGCAGGCTCCTGGAGCCGGAGCCAGCTCGGCACTGGAACCGGCGTCCTCTGGTGGCAGAGAGAGAGCGCTACT
GGCGATTTTCGGACCGAATCGGCACGCTCGTCAGATCCAAGCAGGCGGGACTGGCCTGGAGCAAAAAGAAAGAGAGAGGAGGGCGTAAGG
ATAGACCAAGGAAGAGGGGCTGGGGGGCAGCCTGGGGGCATGAAAAGTGGCCAGGAAGGAGCCAAGACTCCACCAGCAACAATTGAGTTG
CTTCAGCCTCAGTCTAGGGTTCCTTCCAGGCCTTGAACCCCCCAACCTCACAAGGGTTGGAAAGTGAGGCCGGTGAACTTTCCAGCTGGT
ACTTTGATTTTAAAATAATAATAATAATTTTTTCACCCTAGTTCGGTTGGGTGCTCCATCTTACGGAGCCCCAAACTTATTTTGAGAGGC
CGCCACCGTGTTATGGGCGTGCGCAACTGCCTCTACGGCAATAATATGTCAGGACAACGCGATATCCCCCCTGAAATCGGGGAACAGCCC
GAGCAACCACCTTTGGAGGCCCCAGGGGCAGCTGCCCCCGGTGCTGGGCCTAGCCCAGCCGAAGAGATGGAGACCGAACCGCCTCACAAC
GAGCCCATCCCCGTCGAGAATGATGGCGAGGCCTGTGGACCCCCAGAGGTCTCCAGACCCAACTTTCAGGTCCTCAACCCGGCATTCAGG
GAAGCTGGAGCCCATGGAAGCTACAGCCCACCTCCTGAGGAAGCAATGCCCTTCGAGGCTGAACAGCCCAGCTTGGGAGGCTTCTGGCCT
ACACTGGAGCAGCCTGGATTCCCCAGTGGGGTCCATGCAGGCCTTGAGGCCTTCGGCCCAGCACTCATGGAGCCCGGAGCCTTCAGTGGT
GCCAGACCAGGCCTGGGAGGATACAGCCCTCCACCAGAAGAAGCTATGCCCTTTGAGTTTGACCAGCCTGCCCAGAGAGGCTGCAGTCAA
CTTCTCTTACAGGTCCCAGACCTTGCTCCAGGAGGCCCAGGTGCTGCAGGGGTCCCCGGAGCTCCTCCCGAGGAGCCCCAAGCCCTCAGG
CCTGCAAAGGCTGGCTCCAGAGGAGGCTACAGCCCTCCCCCTGAGGAGACTATGCCATTTGAGCTTGATGGAGAAGGATTTGGGGACGAC
AGCCCACCCCCGGGGCTTTCCCGAGTTATCGCACAAGTCGACGGCAGCAGCCAGTTCGCGGCAGTCGCGGCCTCGAGTGCGGTCCGCCTC
ACTCCCGCCGCGAACGCGCCTCCCCTCTGGGTCCCAGGCGCCATCGGCAGCCCATCCCAAGAGGCTGTCAGACCTCCTTCTAACTTCACG
GGCAGCAGCCCCTGGATGGAGATCTCCGGACCCCCGTTCGAGATTGGCAGCGCCCCCGCTGGGGTCGACGACACTCCCGTCAACATGGAC
AGCCCCCCAATCGCGCTTGACGGCCCGCCCATCAAGGTCTCCGGAGCCCCAGATAAGAGAGAGCGAGCAGAGAGACCCCCAGTTGAGGAG
GAAGCAGCAGAGATGGAAGGAGCCGCTGATGCCGCGGAGGGAGGAAAAGTACCCTCTCCGGGGTACGGATCCCCTGCCGCCGGGGCAGCC
TCAGCGGATACCGCTGCCAGGGCAGCCCCTGCAGCCCCAGCCGATCCTGACTCCGGGGCAACCCCAGAAGATCCCGACTCCGGGACAGCA
CCAGCCGATCCTGACTCCGGGGCATTCGCAGCCGATCCCGACTCCGGGGCAGCCCCTGCCGCCCCAGCCGATCCCGACTCCGGGGCGGCC
CCTGACGCCCCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCAGCCGATCCAGATGCCGGGGCGGCCCCTGAGGCTCCCGCCGCC
CCTGCGGCTGCTGAGACCCGGGCAGCCCATGTCGCCCCAGCTGCGCCAGACGCAGGGGCTCCCACTGCCCCAGCCGCTTCTGCCACCCGG
GCAGCCCAAGTCCGCCGGGCGGCCTCTGCAGCCCCTGCCTCCGGGGCCAGACGCAAGATCCATCTCAGACCCCCCAGCCCCGAGATCCAG
GCTGCCGATCCGCCTACTCCGCGGCCTACTCGCGCGTCTGCCTGGCGGGGCAAGTCCGAGAGCAGCCGCGGCCGCCGCGTGTACTACGAT
GAAGGGGTGGCCAGCAGCGACGATGACTCCAGCGGAGACGAGTCCGACGATGGGACCTCCGGATGCCTCCGCTGGTTTCAGCATCGGCGA
AATCGCCGCCGCCGAAAGCCCCAGCGCAACTTACTCCGCAACTTTCTCGTGCAAGCCTTCGGGGGCTGCTTCGGTCGATCTGAGAGTCCC
CAGCCCAAAGCCTCGCGCTCTCTCAAGGTCAAGAAGGTACCCCTGGCGGAGAAGCGCAGACAGATGCGCAAAGAAGCCCTGGAGAAGCGG
GCCCAGAAGCGCGCAGAGAAGAAACGCAGTAAGCTCATCGACAAACAACTCCAGGACGAAAAGATGGGCTACATGTGTACGCACCGCCTG
CTGCTTCTAGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGC
GAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATT
GAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGT
GTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTAC
GAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGC
GATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGAC
GTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTAC
AACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGC
ACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCA
GAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGAT
GAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGC
CGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTA
AAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTC
CCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAA
AAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAAC
AAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAATCAGAATCATTCC
TATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCACCAACTCCACATTGGTT
ACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTA
CTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAA
CCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAGAATTAGCAACTTTATT
ATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCACAAAATGAGAATTATA
TTTGTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAACATAGGGTGACTTGTGTTTTTAGGTATTTAAATAATAAAATTT
CAAGGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGATTTACTACTTTATATAAAATAGTACCTCCTTCAGTTACTGTTTC
TGATTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTTTAAAGCAGTCCAAATTTGGACCTTAGCAATCATG
TCTTTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTACTTTTCAGAATACTAAAGACTTTATAACTGCATGAACTTGGAT
TTTTTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATACCATCCAAATTCTTGCTTTTAATAACAAAGGTACAATATTTTG
TTTTAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATTAAATCCACAATATTTTATTACATTTTTAACTTGTATAAATTTT
AGGTCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAATCACAAATGGCTCTTTTGTGTAATTGTTTAATTTCACCTGAATA
TCATAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCATATTTATTCCATTGTTTTAGTCTGGCTATTTACAGTATAAAAAA
AGCATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTATGCATATAGTAAGTATTACATTCTTAGAGTAGAGCAGAGTTTTT
AGTTAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATATTTCCAAAACTGTTACTGAGAATGGGTCAAGATCAGTGAGAAAT
CTTTACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGTAATGCTTGGAATAAAAACTCTTAAGGCAACTCACTGATTTACT
TCTAGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAAGGTAATGTGTAAAATCAGTCTCGGCTGTCAGAATAACTTCTAA
AAGGTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCTTTCTGAAGTTCGTTAGTATAAATTACTTTTCTAGGATTATTAA
TAAAAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGAGTGGTGAACCTTCTAGAGGAATATATGATTTATTCACAGTTCC
TCAAGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTACATCATGTTGTACATTAGAAATGGAGAGTTTAATAGCTCTTTA
ACTGCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTGACTATTTTGCTGTGTTTTAAAAATGATTGAAATTTATCTTGCC
ATATCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAATATATTCGTAAAATAGGAGCACATTTAGTTGAGGTATACAAGGT
AGGACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAAGTAATGGGTCTTGGAGTATAGATTTTTATTAGTAGCTTGAAAG
AGCTTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAATTTTTTAAGAAAAATATTTTTATCCTAGGGCCAAGTGTTGCCT
GCCACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTTTTACCACCTAGTAACAGTCATTTCTGAAAATATGTTGGATAGA
AAGTCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTATTCCTTTTATGGCATCTATCTTGAAAGTAATCTTGTATTGGAG
ATTGAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTACCTTTATGAAATATAGTTTTGTATAATAGCATAGATTTTCCTTC
AAAAAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATTTGAAAGCCTACTTTCTGAAGAAAATGGTGGGATTTTTTTTTAT
CATGATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTAAAACATTTGAAATACTACCATATTTGTGATTTATTGAGAATAA
AAATCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAAGAAAACATGAATGAACTAGAAGATATTAAAAACATTTGACATT
GGTAAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATTTCAGAATTGATATTTTGAGAAAAATACATGTGAGTCATTTTTT
CTGTTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGAAAGGTAAAACAATTAGTCAAAATATTATTGCCATCATTCTACC
TGTGTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTACATTTCCATAAAGAAAACTCAAGTATTAATAAAAGAGACTTTAC
TGGCTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCTAAGGGAGAGATTTGTGTGATAAAAGTATTGTATATAATAGATC
AGCGATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCCTAAGTTGCAAAATGTAATGATGAGCTTGGTGGAGAAGAATGAG
TCGTTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCACCTTGTTTGCATTCTTGGATAGCTTGTATATGTAGTAGTTTGAT
GAATAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGATCAAAAAAGGCAGATGAAATTACTTAATACTCAGTGTTTTGGA
GAGTATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAATATGCAGCATGCAATATATGCTTATATTTCATTTTAATTTCTGA
TATATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTTGTCATTGTTCTCAAGTGCAATATAACAATGTAACCAAATCTAG
ATAATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAATATTTGTATTATTTTTGTTAGCAGGAAAGAGTGATTAAGTGAGG
TTATTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAAATGAATTATTCTTTACCAGTTTTGAAACACTTTGAAATATCCT
AAGGTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTAATAACATAGAAAGTAAATATCTTTGTGGTCACCCACATTGGGT
GAGACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGATTTGAGTTAGTGAAAACTGGTACAGTGTTCTGCTTGATTTACA

>33630_33630_17_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371100_ITGAV_chr2_187540547_ENST00000374907_length(amino acids)=1044AA_BP=
MRGRHRVMGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNP
AFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRG
CSQLLLQVPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSA
VRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPP
VEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDS
GAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSP
EIQAADPPTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRS
ESPQPKASRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNG
EGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR
ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS
SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYF

--------------------------------------------------------------
>33630_33630_18_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371100_ITGAV_chr2_187540547_ENST00000433736_length(transcript)=4505nt_BP=4029nt
AAAGACTCCAAATCAGTCAGGGAGAGGAGTGGAAGGAGCCAAAACGTCCCTGCGAGGCCTGCGCTCACCAGCCCCCTTACCCAAAGTCCC
GGGCCCCTGGCGCCAGGAGCAGGCTCCTGGAGCCGGAGCCAGCTCGGCACTGGAACCGGCGTCCTCTGGTGGCAGAGAGAGAGCGCTACT
GGCGATTTTCGGACCGAATCGGCACGCTCGTCAGATCCAAGCAGGCGGGACTGGCCTGGAGCAAAAAGAAAGAGAGAGGAGGGCGTAAGG
ATAGACCAAGGAAGAGGGGCTGGGGGGCAGCCTGGGGGCATGAAAAGTGGCCAGGAAGGAGCCAAGACTCCACCAGCAACAATTGAGTTG
CTTCAGCCTCAGTCTAGGGTTCCTTCCAGGCCTTGAACCCCCCAACCTCACAAGGGTTGGAAAGTGAGGCCGGTGAACTTTCCAGCTGGT
ACTTTGATTTTAAAATAATAATAATAATTTTTTCACCCTAGTTCGGTTGGGTGCTCCATCTTACGGAGCCCCAAACTTATTTTGAGAGGC
CGCCACCGTGTTATGGGCGTGCGCAACTGCCTCTACGGCAATAATATGTCAGGACAACGCGATATCCCCCCTGAAATCGGGGAACAGCCC
GAGCAACCACCTTTGGAGGCCCCAGGGGCAGCTGCCCCCGGTGCTGGGCCTAGCCCAGCCGAAGAGATGGAGACCGAACCGCCTCACAAC
GAGCCCATCCCCGTCGAGAATGATGGCGAGGCCTGTGGACCCCCAGAGGTCTCCAGACCCAACTTTCAGGTCCTCAACCCGGCATTCAGG
GAAGCTGGAGCCCATGGAAGCTACAGCCCACCTCCTGAGGAAGCAATGCCCTTCGAGGCTGAACAGCCCAGCTTGGGAGGCTTCTGGCCT
ACACTGGAGCAGCCTGGATTCCCCAGTGGGGTCCATGCAGGCCTTGAGGCCTTCGGCCCAGCACTCATGGAGCCCGGAGCCTTCAGTGGT
GCCAGACCAGGCCTGGGAGGATACAGCCCTCCACCAGAAGAAGCTATGCCCTTTGAGTTTGACCAGCCTGCCCAGAGAGGCTGCAGTCAA
CTTCTCTTACAGGTCCCAGACCTTGCTCCAGGAGGCCCAGGTGCTGCAGGGGTCCCCGGAGCTCCTCCCGAGGAGCCCCAAGCCCTCAGG
CCTGCAAAGGCTGGCTCCAGAGGAGGCTACAGCCCTCCCCCTGAGGAGACTATGCCATTTGAGCTTGATGGAGAAGGATTTGGGGACGAC
AGCCCACCCCCGGGGCTTTCCCGAGTTATCGCACAAGTCGACGGCAGCAGCCAGTTCGCGGCAGTCGCGGCCTCGAGTGCGGTCCGCCTC
ACTCCCGCCGCGAACGCGCCTCCCCTCTGGGTCCCAGGCGCCATCGGCAGCCCATCCCAAGAGGCTGTCAGACCTCCTTCTAACTTCACG
GGCAGCAGCCCCTGGATGGAGATCTCCGGACCCCCGTTCGAGATTGGCAGCGCCCCCGCTGGGGTCGACGACACTCCCGTCAACATGGAC
AGCCCCCCAATCGCGCTTGACGGCCCGCCCATCAAGGTCTCCGGAGCCCCAGATAAGAGAGAGCGAGCAGAGAGACCCCCAGTTGAGGAG
GAAGCAGCAGAGATGGAAGGAGCCGCTGATGCCGCGGAGGGAGGAAAAGTACCCTCTCCGGGGTACGGATCCCCTGCCGCCGGGGCAGCC
TCAGCGGATACCGCTGCCAGGGCAGCCCCTGCAGCCCCAGCCGATCCTGACTCCGGGGCAACCCCAGAAGATCCCGACTCCGGGACAGCA
CCAGCCGATCCTGACTCCGGGGCATTCGCAGCCGATCCCGACTCCGGGGCAGCCCCTGCCGCCCCAGCCGATCCCGACTCCGGGGCGGCC
CCTGACGCCCCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCAGCCGATCCAGATGCCGGGGCGGCCCCTGAGGCTCCCGCCGCC
CCTGCGGCTGCTGAGACCCGGGCAGCCCATGTCGCCCCAGCTGCGCCAGACGCAGGGGCTCCCACTGCCCCAGCCGCTTCTGCCACCCGG
GCAGCCCAAGTCCGCCGGGCGGCCTCTGCAGCCCCTGCCTCCGGGGCCAGACGCAAGATCCATCTCAGACCCCCCAGCCCCGAGATCCAG
GCTGCCGATCCGCCTACTCCGCGGCCTACTCGCGCGTCTGCCTGGCGGGGCAAGTCCGAGAGCAGCCGCGGCCGCCGCGTGTACTACGAT
GAAGGGGTGGCCAGCAGCGACGATGACTCCAGCGGAGACGAGTCCGACGATGGGACCTCCGGATGCCTCCGCTGGTTTCAGCATCGGCGA
AATCGCCGCCGCCGAAAGCCCCAGCGCAACTTACTCCGCAACTTTCTCGTGCAAGCCTTCGGGGGCTGCTTCGGTCGATCTGAGAGTCCC
CAGCCCAAAGCCTCGCGCTCTCTCAAGGTCAAGAAGGTACCCCTGGCGGAGAAGCGCAGACAGATGCGCAAAGAAGCCCTGGAGAAGCGG
GCCCAGAAGCGCGCAGAGAAGAAACGCAGTAAGCTCATCGACAAACAACTCCAGGACGAAAAGATGGGCTACATGTGTACGCACCGCCTG
CTGCTTCTAGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGC
GAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATT
GAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGT
GTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTAC
GAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGC
GATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGAC
GTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTAC
AACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGC
ACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCA
GAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGAT
GAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGC
CGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTA
AAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTC
CCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAA
AAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAAC
AAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAATCAGAATCATTCC
TATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCACCAACTCCACATTGGTT
ACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTA
CTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAA
CCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCCACTAGAATTAGCAACTTTATT
ATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATTAACCACAAAATGAGAATTATA

>33630_33630_18_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371100_ITGAV_chr2_187540547_ENST00000433736_length(amino acids)=1044AA_BP=
MRGRHRVMGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNP
AFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRG
CSQLLLQVPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSA
VRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPP
VEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDS
GAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSP
EIQAADPPTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRS
ESPQPKASRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNG
EGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR
ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS
SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYF

--------------------------------------------------------------
>33630_33630_19_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371102_ITGAV_chr2_187540547_ENST00000261023_length(transcript)=7374nt_BP=3438nt
GTTATGGGCGTGCGCAACTGCCTCTACGGCAATAATATGTCAGGACAACGCGATATCCCCCCTGAAATCGGGGAACAGCCCGAGCAACCA
CCTTTGGAGGCCCCAGGGGCAGCTGCCCCCGGTGCTGGGCCTAGCCCAGCCGAAGAGATGGAGACCGAACCGCCTCACAACGAGCCCATC
CCCGTCGAGAATGATGGCGAGGCCTGTGGACCCCCAGAGGTCTCCAGACCCAACTTTCAGGTCCTCAACCCGGCATTCAGGGAAGCTGGA
GCCCATGGAAGCTACAGCCCACCTCCTGAGGAAGCAATGCCCTTCGAGGCTGAACAGCCCAGCTTGGGAGGCTTCTGGCCTACACTGGAG
CAGCCTGGATTCCCCAGTGGGGTCCATGCAGGCCTTGAGGCCTTCGGCCCAGCACTCATGGAGCCCGGAGCCTTCAGTGGTGCCAGACCA
GGCCTGGGAGGATACAGCCCTCCACCAGAAGAAGCTATGCCCTTTGAGTTTGACCAGCCTGCCCAGAGAGGCTGCAGTCAACTTCTCTTA
CAGGTCCCAGACCTTGCTCCAGGAGGCCCAGGTGCTGCAGGGGTCCCCGGAGCTCCTCCCGAGGAGCCCCAAGCCCTCAGGCCTGCAAAG
GCTGGCTCCAGAGGAGGCTACAGCCCTCCCCCTGAGGAGACTATGCCATTTGAGCTTGATGGAGAAGGATTTGGGGACGACAGCCCACCC
CCGGGGCTTTCCCGAGTTATCGCACAAGTCGACGGCAGCAGCCAGTTCGCGGCAGTCGCGGCCTCGAGTGCGGTCCGCCTCACTCCCGCC
GCGAACGCGCCTCCCCTCTGGGTCCCAGGCGCCATCGGCAGCCCATCCCAAGAGGCTGTCAGACCTCCTTCTAACTTCACGGGCAGCAGC
CCCTGGATGGAGATCTCCGGACCCCCGTTCGAGATTGGCAGCGCCCCCGCTGGGGTCGACGACACTCCCGTCAACATGGACAGCCCCCCA
ATCGCGCTTGACGGCCCGCCCATCAAGGTCTCCGGAGCCCCAGATAAGAGAGAGCGAGCAGAGAGACCCCCAGTTGAGGAGGAAGCAGCA
GAGATGGAAGGAGCCGCTGATGCCGCGGAGGGAGGAAAAGTACCCTCTCCGGGGTACGGATCCCCTGCCGCCGGGGCAGCCTCAGCGGAT
ACCGCTGCCAGGGCAGCCCCTGCAGCCCCAGCCGATCCTGACTCCGGGGCAACCCCAGAAGATCCCGACTCCGGGACAGCACCAGCCGAT
CCTGACTCCGGGGCATTCGCAGCCGATCCCGACTCCGGGGCAGCCCCTGCCGCCCCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCC
CCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCAGCCGATCCAGATGCCGGGGCGGCCCCTGAGGCTCCCGCCGCCCCTGCGGCT
GCTGAGACCCGGGCAGCCCATGTCGCCCCAGCTGCGCCAGACGCAGGGGCTCCCACTGCCCCAGCCGCTTCTGCCACCCGGGCAGCCCAA
GTCCGCCGGGCGGCCTCTGCAGCCCCTGCCTCCGGGGCCAGACGCAAGATCCATCTCAGACCCCCCAGCCCCGAGATCCAGGCTGCCGAT
CCGCCTACTCCGCGGCCTACTCGCGCGTCTGCCTGGCGGGGCAAGTCCGAGAGCAGCCGCGGCCGCCGCGTGTACTACGATGAAGGGGTG
GCCAGCAGCGACGATGACTCCAGCGGAGACGAGTCCGACGATGGGACCTCCGGATGCCTCCGCTGGTTTCAGCATCGGCGAAATCGCCGC
CGCCGAAAGCCCCAGCGCAACTTACTCCGCAACTTTCTCGTGCAAGCCTTCGGGGGCTGCTTCGGTCGATCTGAGAGTCCCCAGCCCAAA
GCCTCGCGCTCTCTCAAGGTCAAGAAGGTACCCCTGGCGGAGAAGCGCAGACAGATGCGCAAAGAAGCCCTGGAGAAGCGGGCCCAGAAG
CGCGCAGAGAAGAAACGCAGTAAGCTCATCGACAAACAACTCCAGGACGAAAAGATGGGCTACATGTGTACGCACCGCCTGCTGCTTCTA
GGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGACAGTGAGAAGGCAACC
AAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCC
AACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCC
AAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGAC
AAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACC
AAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGAT
GTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTG
AACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAA
GTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAG
GACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTAC
CCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAG
TACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTA
ATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAG
ATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAA
AACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAA
TTAAATGTGAGCAAAGAAAAAGAAAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAG
AATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTG
TGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTC
CGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGT
TATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTG
ATAGTGCTAATTGGCATTAACCACAAAATGAGAATTATATTTGTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAACATA
GGGTGACTTGTGTTTTTAGGTATTTAAATAATAAAATTTCAAGGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGATTTAC
TACTTTATATAAAATAGTACCTCCTTCAGTTACTGTTTCTGATTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTGTTGT
TGTTTTAAAGCAGTCCAAATTTGGACCTTAGCAATCATGTCTTTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTACTTT
TCAGAATACTAAAGACTTTATAACTGCATGAACTTGGATTTTTTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATACCAT
CCAAATTCTTGCTTTTAATAACAAAGGTACAATATTTTGTTTTAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATTAAAT
CCACAATATTTTATTACATTTTTAACTTGTATAAATTTTAGGTCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAATCACA
AATGGCTCTTTTGTGTAATTGTTTAATTTCACCTGAATATCATAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCATATTT
ATTCCATTGTTTTAGTCTGGCTATTTACAGTATAAAAAAAGCATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTATGCAT
ATAGTAAGTATTACATTCTTAGAGTAGAGCAGAGTTTTTAGTTAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATATTTCC
AAAACTGTTACTGAGAATGGGTCAAGATCAGTGAGAAATCTTTACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGTAATG
CTTGGAATAAAAACTCTTAAGGCAACTCACTGATTTACTTCTAGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAAGGTA
ATGTGTAAAATCAGTCTCGGCTGTCAGAATAACTTCTAAAAGGTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCTTTCT
GAAGTTCGTTAGTATAAATTACTTTTCTAGGATTATTAATAAAAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGAGTGG
TGAACCTTCTAGAGGAATATATGATTTATTCACAGTTCCTCAAGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTACATC
ATGTTGTACATTAGAAATGGAGAGTTTAATAGCTCTTTAACTGCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTGACTA
TTTTGCTGTGTTTTAAAAATGATTGAAATTTATCTTGCCATATCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAATATAT
TCGTAAAATAGGAGCACATTTAGTTGAGGTATACAAGGTAGGACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAAGTAA
TGGGTCTTGGAGTATAGATTTTTATTAGTAGCTTGAAAGAGCTTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAATTTT
TTAAGAAAAATATTTTTATCCTAGGGCCAAGTGTTGCCTGCCACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTTTTAC
CACCTAGTAACAGTCATTTCTGAAAATATGTTGGATAGAAAGTCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTATTCC
TTTTATGGCATCTATCTTGAAAGTAATCTTGTATTGGAGATTGAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTACCTTT
ATGAAATATAGTTTTGTATAATAGCATAGATTTTCCTTCAAAAAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATTTGAA
AGCCTACTTTCTGAAGAAAATGGTGGGATTTTTTTTTATCATGATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTAAAAC
ATTTGAAATACTACCATATTTGTGATTTATTGAGAATAAAAATCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAAGAAA
ACATGAATGAACTAGAAGATATTAAAAACATTTGACATTGGTAAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATTTCAG
AATTGATATTTTGAGAAAAATACATGTGAGTCATTTTTTCTGTTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGAAAGG
TAAAACAATTAGTCAAAATATTATTGCCATCATTCTACCTGTGTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTACATTT
CCATAAAGAAAACTCAAGTATTAATAAAAGAGACTTTACTGGCTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCTAAGG
GAGAGATTTGTGTGATAAAAGTATTGTATATAATAGATCAGCGATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCCTAAG
TTGCAAAATGTAATGATGAGCTTGGTGGAGAAGAATGAGTCGTTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCACCTTG
TTTGCATTCTTGGATAGCTTGTATATGTAGTAGTTTGATGAATAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGATCAA
AAAAGGCAGATGAAATTACTTAATACTCAGTGTTTTGGAGAGTATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAATATGC
AGCATGCAATATATGCTTATATTTCATTTTAATTTCTGATATATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTTGTCA
TTGTTCTCAAGTGCAATATAACAATGTAACCAAATCTAGATAATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAATATTT
GTATTATTTTTGTTAGCAGGAAAGAGTGATTAAGTGAGGTTATTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAAATGA
ATTATTCTTTACCAGTTTTGAAACACTTTGAAATATCCTAAGGTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTAATAA
CATAGAAAGTAAATATCTTTGTGGTCACCCACATTGGGTGAGACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGATTTG

>33630_33630_19_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371102_ITGAV_chr2_187540547_ENST00000261023_length(amino acids)=1023AA_BP=
MGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAGA
HGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQ
VPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAVRLTPAA
NAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAE
MEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAP
ADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADP
PTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRSESPQPKA
SRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKATK
VQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDK
IDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALN
LFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYP

--------------------------------------------------------------
>33630_33630_20_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371102_ITGAV_chr2_187540547_ENST00000374907_length(transcript)=7370nt_BP=3438nt
GTTATGGGCGTGCGCAACTGCCTCTACGGCAATAATATGTCAGGACAACGCGATATCCCCCCTGAAATCGGGGAACAGCCCGAGCAACCA
CCTTTGGAGGCCCCAGGGGCAGCTGCCCCCGGTGCTGGGCCTAGCCCAGCCGAAGAGATGGAGACCGAACCGCCTCACAACGAGCCCATC
CCCGTCGAGAATGATGGCGAGGCCTGTGGACCCCCAGAGGTCTCCAGACCCAACTTTCAGGTCCTCAACCCGGCATTCAGGGAAGCTGGA
GCCCATGGAAGCTACAGCCCACCTCCTGAGGAAGCAATGCCCTTCGAGGCTGAACAGCCCAGCTTGGGAGGCTTCTGGCCTACACTGGAG
CAGCCTGGATTCCCCAGTGGGGTCCATGCAGGCCTTGAGGCCTTCGGCCCAGCACTCATGGAGCCCGGAGCCTTCAGTGGTGCCAGACCA
GGCCTGGGAGGATACAGCCCTCCACCAGAAGAAGCTATGCCCTTTGAGTTTGACCAGCCTGCCCAGAGAGGCTGCAGTCAACTTCTCTTA
CAGGTCCCAGACCTTGCTCCAGGAGGCCCAGGTGCTGCAGGGGTCCCCGGAGCTCCTCCCGAGGAGCCCCAAGCCCTCAGGCCTGCAAAG
GCTGGCTCCAGAGGAGGCTACAGCCCTCCCCCTGAGGAGACTATGCCATTTGAGCTTGATGGAGAAGGATTTGGGGACGACAGCCCACCC
CCGGGGCTTTCCCGAGTTATCGCACAAGTCGACGGCAGCAGCCAGTTCGCGGCAGTCGCGGCCTCGAGTGCGGTCCGCCTCACTCCCGCC
GCGAACGCGCCTCCCCTCTGGGTCCCAGGCGCCATCGGCAGCCCATCCCAAGAGGCTGTCAGACCTCCTTCTAACTTCACGGGCAGCAGC
CCCTGGATGGAGATCTCCGGACCCCCGTTCGAGATTGGCAGCGCCCCCGCTGGGGTCGACGACACTCCCGTCAACATGGACAGCCCCCCA
ATCGCGCTTGACGGCCCGCCCATCAAGGTCTCCGGAGCCCCAGATAAGAGAGAGCGAGCAGAGAGACCCCCAGTTGAGGAGGAAGCAGCA
GAGATGGAAGGAGCCGCTGATGCCGCGGAGGGAGGAAAAGTACCCTCTCCGGGGTACGGATCCCCTGCCGCCGGGGCAGCCTCAGCGGAT
ACCGCTGCCAGGGCAGCCCCTGCAGCCCCAGCCGATCCTGACTCCGGGGCAACCCCAGAAGATCCCGACTCCGGGACAGCACCAGCCGAT
CCTGACTCCGGGGCATTCGCAGCCGATCCCGACTCCGGGGCAGCCCCTGCCGCCCCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCC
CCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCAGCCGATCCAGATGCCGGGGCGGCCCCTGAGGCTCCCGCCGCCCCTGCGGCT
GCTGAGACCCGGGCAGCCCATGTCGCCCCAGCTGCGCCAGACGCAGGGGCTCCCACTGCCCCAGCCGCTTCTGCCACCCGGGCAGCCCAA
GTCCGCCGGGCGGCCTCTGCAGCCCCTGCCTCCGGGGCCAGACGCAAGATCCATCTCAGACCCCCCAGCCCCGAGATCCAGGCTGCCGAT
CCGCCTACTCCGCGGCCTACTCGCGCGTCTGCCTGGCGGGGCAAGTCCGAGAGCAGCCGCGGCCGCCGCGTGTACTACGATGAAGGGGTG
GCCAGCAGCGACGATGACTCCAGCGGAGACGAGTCCGACGATGGGACCTCCGGATGCCTCCGCTGGTTTCAGCATCGGCGAAATCGCCGC
CGCCGAAAGCCCCAGCGCAACTTACTCCGCAACTTTCTCGTGCAAGCCTTCGGGGGCTGCTTCGGTCGATCTGAGAGTCCCCAGCCCAAA
GCCTCGCGCTCTCTCAAGGTCAAGAAGGTACCCCTGGCGGAGAAGCGCAGACAGATGCGCAAAGAAGCCCTGGAGAAGCGGGCCCAGAAG
CGCGCAGAGAAGAAACGCAGTAAGCTCATCGACAAACAACTCCAGGACGAAAAGATGGGCTACATGTGTACGCACCGCCTGCTGCTTCTA
GGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGACAGTGAGAAGGCAACC
AAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCC
AACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCC
AAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGAC
AAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACC
AAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGAT
GTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTG
AACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAA
GTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAG
GACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTAC
CCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAG
TACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTA
ATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAG
ATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAA
AACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAA
TTAAATGTGAGCAAAGAAAAAGAAAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAG
AATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTG
TGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTC
CGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGT
TATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTG
ATAGTGCTAATTGGCATTAACCACAAAATGAGAATTATATTTGTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAACATA
GGGTGACTTGTGTTTTTAGGTATTTAAATAATAAAATTTCAAGGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGATTTAC
TACTTTATATAAAATAGTACCTCCTTCAGTTACTGTTTCTGATTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTGTTGT
TGTTTTAAAGCAGTCCAAATTTGGACCTTAGCAATCATGTCTTTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTACTTT
TCAGAATACTAAAGACTTTATAACTGCATGAACTTGGATTTTTTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATACCAT
CCAAATTCTTGCTTTTAATAACAAAGGTACAATATTTTGTTTTAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATTAAAT
CCACAATATTTTATTACATTTTTAACTTGTATAAATTTTAGGTCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAATCACA
AATGGCTCTTTTGTGTAATTGTTTAATTTCACCTGAATATCATAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCATATTT
ATTCCATTGTTTTAGTCTGGCTATTTACAGTATAAAAAAAGCATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTATGCAT
ATAGTAAGTATTACATTCTTAGAGTAGAGCAGAGTTTTTAGTTAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATATTTCC
AAAACTGTTACTGAGAATGGGTCAAGATCAGTGAGAAATCTTTACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGTAATG
CTTGGAATAAAAACTCTTAAGGCAACTCACTGATTTACTTCTAGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAAGGTA
ATGTGTAAAATCAGTCTCGGCTGTCAGAATAACTTCTAAAAGGTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCTTTCT
GAAGTTCGTTAGTATAAATTACTTTTCTAGGATTATTAATAAAAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGAGTGG
TGAACCTTCTAGAGGAATATATGATTTATTCACAGTTCCTCAAGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTACATC
ATGTTGTACATTAGAAATGGAGAGTTTAATAGCTCTTTAACTGCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTGACTA
TTTTGCTGTGTTTTAAAAATGATTGAAATTTATCTTGCCATATCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAATATAT
TCGTAAAATAGGAGCACATTTAGTTGAGGTATACAAGGTAGGACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAAGTAA
TGGGTCTTGGAGTATAGATTTTTATTAGTAGCTTGAAAGAGCTTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAATTTT
TTAAGAAAAATATTTTTATCCTAGGGCCAAGTGTTGCCTGCCACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTTTTAC
CACCTAGTAACAGTCATTTCTGAAAATATGTTGGATAGAAAGTCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTATTCC
TTTTATGGCATCTATCTTGAAAGTAATCTTGTATTGGAGATTGAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTACCTTT
ATGAAATATAGTTTTGTATAATAGCATAGATTTTCCTTCAAAAAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATTTGAA
AGCCTACTTTCTGAAGAAAATGGTGGGATTTTTTTTTATCATGATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTAAAAC
ATTTGAAATACTACCATATTTGTGATTTATTGAGAATAAAAATCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAAGAAA
ACATGAATGAACTAGAAGATATTAAAAACATTTGACATTGGTAAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATTTCAG
AATTGATATTTTGAGAAAAATACATGTGAGTCATTTTTTCTGTTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGAAAGG
TAAAACAATTAGTCAAAATATTATTGCCATCATTCTACCTGTGTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTACATTT
CCATAAAGAAAACTCAAGTATTAATAAAAGAGACTTTACTGGCTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCTAAGG
GAGAGATTTGTGTGATAAAAGTATTGTATATAATAGATCAGCGATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCCTAAG
TTGCAAAATGTAATGATGAGCTTGGTGGAGAAGAATGAGTCGTTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCACCTTG
TTTGCATTCTTGGATAGCTTGTATATGTAGTAGTTTGATGAATAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGATCAA
AAAAGGCAGATGAAATTACTTAATACTCAGTGTTTTGGAGAGTATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAATATGC
AGCATGCAATATATGCTTATATTTCATTTTAATTTCTGATATATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTTGTCA
TTGTTCTCAAGTGCAATATAACAATGTAACCAAATCTAGATAATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAATATTT
GTATTATTTTTGTTAGCAGGAAAGAGTGATTAAGTGAGGTTATTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAAATGA
ATTATTCTTTACCAGTTTTGAAACACTTTGAAATATCCTAAGGTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTAATAA
CATAGAAAGTAAATATCTTTGTGGTCACCCACATTGGGTGAGACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGATTTG

>33630_33630_20_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371102_ITGAV_chr2_187540547_ENST00000374907_length(amino acids)=1023AA_BP=
MGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAGA
HGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQ
VPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAVRLTPAA
NAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAE
MEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAP
ADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADP
PTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRSESPQPKA
SRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKATK
VQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDK
IDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALN
LFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYP

--------------------------------------------------------------
>33630_33630_21_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371102_ITGAV_chr2_187540547_ENST00000433736_length(transcript)=3914nt_BP=3438nt
GTTATGGGCGTGCGCAACTGCCTCTACGGCAATAATATGTCAGGACAACGCGATATCCCCCCTGAAATCGGGGAACAGCCCGAGCAACCA
CCTTTGGAGGCCCCAGGGGCAGCTGCCCCCGGTGCTGGGCCTAGCCCAGCCGAAGAGATGGAGACCGAACCGCCTCACAACGAGCCCATC
CCCGTCGAGAATGATGGCGAGGCCTGTGGACCCCCAGAGGTCTCCAGACCCAACTTTCAGGTCCTCAACCCGGCATTCAGGGAAGCTGGA
GCCCATGGAAGCTACAGCCCACCTCCTGAGGAAGCAATGCCCTTCGAGGCTGAACAGCCCAGCTTGGGAGGCTTCTGGCCTACACTGGAG
CAGCCTGGATTCCCCAGTGGGGTCCATGCAGGCCTTGAGGCCTTCGGCCCAGCACTCATGGAGCCCGGAGCCTTCAGTGGTGCCAGACCA
GGCCTGGGAGGATACAGCCCTCCACCAGAAGAAGCTATGCCCTTTGAGTTTGACCAGCCTGCCCAGAGAGGCTGCAGTCAACTTCTCTTA
CAGGTCCCAGACCTTGCTCCAGGAGGCCCAGGTGCTGCAGGGGTCCCCGGAGCTCCTCCCGAGGAGCCCCAAGCCCTCAGGCCTGCAAAG
GCTGGCTCCAGAGGAGGCTACAGCCCTCCCCCTGAGGAGACTATGCCATTTGAGCTTGATGGAGAAGGATTTGGGGACGACAGCCCACCC
CCGGGGCTTTCCCGAGTTATCGCACAAGTCGACGGCAGCAGCCAGTTCGCGGCAGTCGCGGCCTCGAGTGCGGTCCGCCTCACTCCCGCC
GCGAACGCGCCTCCCCTCTGGGTCCCAGGCGCCATCGGCAGCCCATCCCAAGAGGCTGTCAGACCTCCTTCTAACTTCACGGGCAGCAGC
CCCTGGATGGAGATCTCCGGACCCCCGTTCGAGATTGGCAGCGCCCCCGCTGGGGTCGACGACACTCCCGTCAACATGGACAGCCCCCCA
ATCGCGCTTGACGGCCCGCCCATCAAGGTCTCCGGAGCCCCAGATAAGAGAGAGCGAGCAGAGAGACCCCCAGTTGAGGAGGAAGCAGCA
GAGATGGAAGGAGCCGCTGATGCCGCGGAGGGAGGAAAAGTACCCTCTCCGGGGTACGGATCCCCTGCCGCCGGGGCAGCCTCAGCGGAT
ACCGCTGCCAGGGCAGCCCCTGCAGCCCCAGCCGATCCTGACTCCGGGGCAACCCCAGAAGATCCCGACTCCGGGACAGCACCAGCCGAT
CCTGACTCCGGGGCATTCGCAGCCGATCCCGACTCCGGGGCAGCCCCTGCCGCCCCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCC
CCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCAGCCGATCCAGATGCCGGGGCGGCCCCTGAGGCTCCCGCCGCCCCTGCGGCT
GCTGAGACCCGGGCAGCCCATGTCGCCCCAGCTGCGCCAGACGCAGGGGCTCCCACTGCCCCAGCCGCTTCTGCCACCCGGGCAGCCCAA
GTCCGCCGGGCGGCCTCTGCAGCCCCTGCCTCCGGGGCCAGACGCAAGATCCATCTCAGACCCCCCAGCCCCGAGATCCAGGCTGCCGAT
CCGCCTACTCCGCGGCCTACTCGCGCGTCTGCCTGGCGGGGCAAGTCCGAGAGCAGCCGCGGCCGCCGCGTGTACTACGATGAAGGGGTG
GCCAGCAGCGACGATGACTCCAGCGGAGACGAGTCCGACGATGGGACCTCCGGATGCCTCCGCTGGTTTCAGCATCGGCGAAATCGCCGC
CGCCGAAAGCCCCAGCGCAACTTACTCCGCAACTTTCTCGTGCAAGCCTTCGGGGGCTGCTTCGGTCGATCTGAGAGTCCCCAGCCCAAA
GCCTCGCGCTCTCTCAAGGTCAAGAAGGTACCCCTGGCGGAGAAGCGCAGACAGATGCGCAAAGAAGCCCTGGAGAAGCGGGCCCAGAAG
CGCGCAGAGAAGAAACGCAGTAAGCTCATCGACAAACAACTCCAGGACGAAAAGATGGGCTACATGTGTACGCACCGCCTGCTGCTTCTA
GGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGACAGTGAGAAGGCAACC
AAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCC
AACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCC
AAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGAC
AAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACC
AAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGAT
GTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTG
AACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAA
GTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAG
GACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTAC
CCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAG
TACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTA
ATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAG
ATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAA
AACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAA
TTAAATGTGAGCAAAGAAAAAGAAAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAG
AATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTG
TGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTC
CGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGT
TATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTG

>33630_33630_21_GNAS-ITGAV_GNAS_chr20_57486241_ENST00000371102_ITGAV_chr2_187540547_ENST00000433736_length(amino acids)=1023AA_BP=
MGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAGA
HGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQ
VPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAVRLTPAA
NAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAE
MEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAP
ADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADP
PTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRSESPQPKA
SRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKATK
VQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDK
IDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALN
LFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYP

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Fusion Gene PPI Analysis for GNAS-ITGAV


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GNAS-ITGAV


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GNAS-ITGAV


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource