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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GNAS-PLXNC1 (FusionGDB2 ID:33639)

Fusion Gene Summary for GNAS-PLXNC1

check button Fusion gene summary
Fusion gene informationFusion gene name: GNAS-PLXNC1
Fusion gene ID: 33639
HgeneTgene
Gene symbol

GNAS

PLXNC1

Gene ID

2778

10154

Gene nameGNAS complex locusplexin C1
SynonymsAHO|C20orf45|GNAS1|GPSA|GSA|GSP|NESP|PITA3|POH|SCG6|SgVICD232|PLXN-C1|VESPR
Cytomap

20q13.32

12q22

Type of geneprotein-codingprotein-coding
Descriptionprotein ALEXprotein GNASprotein SCG6 (secretogranin VI)G protein subunit alpha Sadenylate cyclase-stimulating G alpha proteinalternative gene product encoded by XL-exonextra large alphas proteinguanine nucleotide binding protein (G protein), alpha plexin-C1plexin (semaphorin receptor)receptor for viral semaphorin proteinreceptor for virally-encoded semaphorinvirus-encoded semaphorin protein receptor
Modification date2020032920200313
UniProtAcc

P63092

.
Ensembl transtripts involved in fusion geneENST00000265620, ENST00000306090, 
ENST00000313949, ENST00000354359, 
ENST00000371075, ENST00000371085, 
ENST00000371095, ENST00000371100, 
ENST00000371102, ENST00000464624, 
ENST00000306120, ENST00000371081, 
ENST00000371098, ENST00000371099, 
ENST00000545312, ENST00000547057, 
ENST00000551495, ENST00000258526, 
Fusion gene scores* DoF score44 X 25 X 16=176003 X 3 X 2=18
# samples 513
** MAII scorelog2(51/17600*10)=-5.10893437155316
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: GNAS [Title/Abstract] AND PLXNC1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGNAS(57486241)-PLXNC1(94642003), # samples:1
Anticipated loss of major functional domain due to fusion event.GNAS-PLXNC1 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
GNAS-PLXNC1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
GNAS-PLXNC1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
GNAS-PLXNC1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across GNAS (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PLXNC1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PCPGTCGA-RW-A686-06AGNASchr20

57486241

-PLXNC1chr12

94642003

+


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Fusion Gene ORF analysis for GNAS-PLXNC1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000265620ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000265620ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000265620ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000306090ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000306090ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000306090ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000313949ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000313949ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000313949ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000354359ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000354359ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000354359ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371075ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371075ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371075ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371085ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371085ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371085ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371095ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371095ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371095ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371100ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371100ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371100ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371102ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371102ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000371102ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000464624ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000464624ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
5CDS-intronENST00000464624ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+
Frame-shiftENST00000313949ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
Frame-shiftENST00000371075ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
Frame-shiftENST00000464624ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
In-frameENST00000265620ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
In-frameENST00000306090ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
In-frameENST00000354359ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
In-frameENST00000371085ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
In-frameENST00000371095ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
In-frameENST00000371100ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
In-frameENST00000371102ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-3CDSENST00000306120ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-3CDSENST00000371081ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-3CDSENST00000371098ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-3CDSENST00000371099ENST00000258526GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-intronENST00000306120ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-intronENST00000306120ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-intronENST00000306120ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-intronENST00000371081ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-intronENST00000371081ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-intronENST00000371081ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-intronENST00000371098ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-intronENST00000371098ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-intronENST00000371098ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-intronENST00000371099ENST00000545312GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-intronENST00000371099ENST00000547057GNASchr20

57486241

-PLXNC1chr12

94642003

+
intron-intronENST00000371099ENST00000551495GNASchr20

57486241

-PLXNC1chr12

94642003

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000371100GNASchr2057486241-ENST00000258526PLXNC1chr1294642003+8534402953136651044
ENST00000371102GNASchr2057486241-ENST00000258526PLXNC1chr1294642003+79433438330741023
ENST00000371095GNASchr2057486241-ENST00000258526PLXNC1chr1294642003+6436193121234045640
ENST00000371085GNASchr2057486241-ENST00000258526PLXNC1chr1294642003+6477197221644086640
ENST00000354359GNASchr2057486241-ENST00000258526PLXNC1chr1294642003+6480197521674089640
ENST00000265620GNASchr2057486241-ENST00000258526PLXNC1chr1294642003+6371186620583980640
ENST00000306090GNASchr2057486241-ENST00000258526PLXNC1chr1294642003+6147164218343756640

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000371100ENST00000258526GNASchr2057486241-PLXNC1chr1294642003+0.0014484390.99855155
ENST00000371102ENST00000258526GNASchr2057486241-PLXNC1chr1294642003+0.0006858730.9993142
ENST00000371095ENST00000258526GNASchr2057486241-PLXNC1chr1294642003+0.0025772960.9974227
ENST00000371085ENST00000258526GNASchr2057486241-PLXNC1chr1294642003+0.0026826980.99731725
ENST00000354359ENST00000258526GNASchr2057486241-PLXNC1chr1294642003+0.0027236780.99727637
ENST00000265620ENST00000258526GNASchr2057486241-PLXNC1chr1294642003+0.0024826640.99751735
ENST00000306090ENST00000258526GNASchr2057486241-PLXNC1chr1294642003+0.0022458970.99775416

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Fusion Genomic Features for GNAS-PLXNC1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GNAS-PLXNC1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:57486241/chr12:94642003)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GNAS

P63092

.
FUNCTION: Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) (PubMed:17110384). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP (PubMed:26206488, PubMed:8702665). GNAS functions downstream of several GPCRs, including beta-adrenergic receptors (PubMed:21488135). Stimulates the Ras signaling pathway via RAPGEF2 (PubMed:12391161). {ECO:0000269|PubMed:12391161, ECO:0000269|PubMed:17110384, ECO:0000269|PubMed:21488135, ECO:0000269|PubMed:26206488, ECO:0000269|PubMed:8702665}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGNASchr20:57486241chr12:94642003ENST00000371100-1313641_66711591038.0Coiled coilOntology_term=ECO:0000255
HgeneGNASchr20:57486241chr12:94642003ENST00000371100-1313730_75611591038.0Coiled coilOntology_term=ECO:0000255
HgeneGNASchr20:57486241chr12:94642003ENST00000371102-1212641_66711451024.0Coiled coilOntology_term=ECO:0000255
HgeneGNASchr20:57486241chr12:94642003ENST00000371102-1212730_75611451024.0Coiled coilOntology_term=ECO:0000255
HgeneGNASchr20:57486241chr12:94642003ENST00000313949-131378_14272926.333333333333332Compositional biasGlu-rich
HgeneGNASchr20:57486241chr12:94642003ENST00000371075-131378_14273036.333333333333336Compositional biasGlu-rich
HgeneGNASchr20:57486241chr12:94642003ENST00000371100-1313358_52211591038.0Compositional biasAla-rich
HgeneGNASchr20:57486241chr12:94642003ENST00000371102-1212358_52211451024.0Compositional biasAla-rich
HgeneGNASchr20:57486241chr12:94642003ENST00000265620-121239_394501380.0DomainG-alpha
HgeneGNASchr20:57486241chr12:94642003ENST00000306090-131339_394500381.0DomainG-alpha
HgeneGNASchr20:57486241chr12:94642003ENST00000354359-131339_394517396.0DomainG-alpha
HgeneGNASchr20:57486241chr12:94642003ENST00000371085-131339_394516395.0DomainG-alpha
HgeneGNASchr20:57486241chr12:94642003ENST00000371095-121239_394502381.0DomainG-alpha
HgeneGNASchr20:57486241chr12:94642003ENST00000371100-1313682_103711591038.0DomainG-alpha
HgeneGNASchr20:57486241chr12:94642003ENST00000371102-1212682_103711451024.0DomainG-alpha
HgeneGNASchr20:57486241chr12:94642003ENST00000265620-1212197_204501380.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000265620-1212223_227501380.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000265620-1212292_295501380.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000265620-121247_55501380.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000306090-1313197_204500381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000306090-1313223_227500381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000306090-1313292_295500381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000306090-131347_55500381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000354359-1313197_204517396.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000354359-1313223_227517396.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000354359-1313292_295517396.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000354359-131347_55517396.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371085-1313197_204516395.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371085-1313223_227516395.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371085-1313292_295516395.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371085-131347_55516395.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371095-1212197_204502381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371095-1212223_227502381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371095-1212292_295502381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371095-121247_55502381.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371100-1313690_69811591038.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371100-1313840_84711591038.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371100-1313866_87011591038.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371100-1313935_93811591038.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371102-1212690_69811451024.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371102-1212840_84711451024.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371102-1212866_87011451024.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000371102-1212935_93811451024.0Nucleotide bindingGTP
HgeneGNASchr20:57486241chr12:94642003ENST00000265620-1212196_204501380.0RegionG2 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000265620-1212219_228501380.0RegionG3 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000265620-1212288_295501380.0RegionG4 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000265620-1212364_369501380.0RegionG5 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000265620-121242_55501380.0RegionG1 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000306090-1313196_204500381.0RegionG2 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000306090-1313219_228500381.0RegionG3 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000306090-1313288_295500381.0RegionG4 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000306090-1313364_369500381.0RegionG5 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000306090-131342_55500381.0RegionG1 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000354359-1313196_204517396.0RegionG2 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000354359-1313219_228517396.0RegionG3 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000354359-1313288_295517396.0RegionG4 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000354359-1313364_369517396.0RegionG5 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000354359-131342_55517396.0RegionG1 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371085-1313196_204516395.0RegionG2 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371085-1313219_228516395.0RegionG3 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371085-1313288_295516395.0RegionG4 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371085-1313364_369516395.0RegionG5 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371085-131342_55516395.0RegionG1 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371095-1212196_204502381.0RegionG2 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371095-1212219_228502381.0RegionG3 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371095-1212288_295502381.0RegionG4 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371095-1212364_369502381.0RegionG5 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371095-121242_55502381.0RegionG1 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371100-13131007_101211591038.0RegionG5 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371100-1313685_69811591038.0RegionG1 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371100-1313839_84711591038.0RegionG2 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371100-1313862_87111591038.0RegionG3 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371100-1313931_93811591038.0RegionG4 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371102-12121007_101211451024.0RegionG5 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371102-1212685_69811451024.0RegionG1 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371102-1212839_84711451024.0RegionG2 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371102-1212862_87111451024.0RegionG3 motif
HgeneGNASchr20:57486241chr12:94642003ENST00000371102-1212931_93811451024.0RegionG4 motif
TgenePLXNC1chr20:57486241chr12:94642003ENST000002585261231966_15688641569.0Topological domainCytoplasmic
TgenePLXNC1chr20:57486241chr12:94642003ENST000002585261231945_9658641569.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGNASchr20:57486241chr12:94642003ENST00000306120-11238_4760626.0Compositional biasPro-rich
HgeneGNASchr20:57486241chr12:94642003ENST00000371098-1478_142020.333333333333332Compositional biasGlu-rich
TgenePLXNC1chr20:57486241chr12:94642003ENST00000258526123135_4528641569.0DomainSema
TgenePLXNC1chr20:57486241chr12:94642003ENST00000258526123135_9448641569.0Topological domainExtracellular


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Fusion Gene Sequence for GNAS-PLXNC1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>33639_33639_1_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000265620_PLXNC1_chr12_94642003_ENST00000258526_length(transcript)=6371nt_BP=1866nt
GGGCGGCGGCGGGGGCCCGGCCGAGGCAATAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCT
CGGCCCGGCGGCGGCCATCAGCCCCCTCGGCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTT
CCCGCCCGTCCGCGCGCCCCGCGGCCCGCGGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCG
CCCGGCGCTGCCCCGGCCCTCCCGGCCCGCGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCC
GCCATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAG
CTGCAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAG
ATGAGGATCCTGCATGTTAATGGGTTTAATGGAGATGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAA
ACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTG
ATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAA
CGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGAT
CAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTG
GGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAAC
ATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACC
ATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAA
TTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAG
TTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGT
GTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAG
CCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCT
TCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAG
GAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAA
TGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAATGACAACTTCAACATT
TCCAAAAAAGACATTGAAATTACTCTCTTCCATGGGGAAAATGGGCAATTAAATTGCAGTTTTGAAAATATTACTAGAAATCAAGATCTT
ACCACCATCCTTTGCAAAATTAAAGGCATCAAGACTGCAAGCACCATTGCCAACTCTTCTAAGAAAGTTCGGGTCAAGCTGGGAAACCTG
GAGCTCTACGTCGAGCAGGAGTCAGTTCCTTCCACATGGTATTTTCTGATTGTGCTCCCTGTCTTGCTAGTGATTGTCATTTTTGCGGCC
GTGGGGGTGACCAGGCACAAATCGAAGGAGCTGAGTCGCAAACAGAGTCAACAACTAGAATTGCTGGAAAGCGAGCTCCGGAAAGAGATA
CGTGACGGCTTTGCTGAGCTGCAGATGGATAAATTGGATGTGGTTGATAGTTTTGGAACTGTTCCCTTCCTTGACTACAAACATTTTGCT
CTGAGAACTTTCTTCCCTGAGTCAGGTGGCTTCACCCACATCTTCACTGAAGATATGCATAACAGAGACGCCAACGACAAGAATGAAAGT
CTCACAGCTTTGGATGCCCTAATCTGTAATAAAAGCTTTCTTGTTACTGTCATCCACACCCTTGAAAAGCAGAAGAACTTTTCTGTGAAG
GACAGGTGTCTGTTTGCCTCCTTCCTAACCATTGCACTGCAAACCAAGCTGGTCTACCTGACCAGCATCCTAGAGGTGCTGACCAGGGAC
TTGATGGAACAGTGTAGTAACATGCAGCCGAAACTCATGCTGAGACGCACGGAGTCCGTCGTCGAAAAACTCCTCACAAACTGGATGTCC
GTCTGCCTTTCTGGATTTCTCCGGGAGACTGTCGGAGAGCCCTTCTATTTGCTGGTGACGACTCTGAACCAGAAAATTAACAAGGGTCCC
GTGGATGTAATCACTTGCAAAGCCCTGTACACACTTAATGAAGACTGGCTGTTGTGGCAGGTTCCGGAATTCAGTACTGTGGCATTAAAC
GTCGTCTTTGAAAAAATCCCGGAAAACGAGAGTGCAGATGTCTGTCGGAATATTTCAGTCAATGTTCTCGACTGTGACACCATTGGCCAA
GCCAAAGAAAAGATTTTCCAAGCATTCTTAAGCAAAAATGGCTCTCCTTATGGACTTCAGCTTAATGAAATTGGTCTTGAGCTTCAAATG
GGCACACGACAGAAAGAACTTCTGGACATCGACAGTTCCTCCGTGATTCTTGAAGATGGAATCACCAAGCTAAACACCATTGGCCACTAT
GAGATATCAAATGGATCCACTATAAAAGTCTTTAAGAAGATAGCAAATTTTACTTCAGATGTGGAGTACTCGGATGACCACTGCCATTTG
ATTTTACCAGATTCGGAAGCATTCCAAGATGTGCAAGGAAAGAGACATCGAGGGAAGCACAAGTTCAAAGTAAAAGAAATGTATCTGACA
AAGCTGCTGTCGACCAAGGTGGCAATTCATTCTGTGCTTGAAAAACTTTTTAGAAGCATTTGGAGTTTACCCAACAGCAGAGCTCCATTT
GCTATAAAATACTTTTTTGACTTTTTGGACGCCCAGGCTGAAAACAAAAAAATCACAGATCCTGACGTCGTACATATTTGGAAAACAAAC
AGCCTTCCTCTTCGCTTCTGGGTAAACATCCTGAAGAACCCTCAGTTTGTCTTTGACATTAAGAAGACACCACATATAGACGGCTGTTTG
TCAGTGATTGCCCAGGCATTCATGGATGCATTTTCTCTCACAGAGCAGCAACTAGGGAAGGAAGCACCAACTAATAAGCTTCTCTATGCC
AAGGATATCCCAACCTACAAAGAAGAAGTAAAATCTTATTACAAAGCAATCAGGGATTTGCCTCCATTGTCATCCTCAGAAATGGAAGAA
TTTTTAACTCAGGAATCTAAGAAACATGAAAATGAATTTAATGAAGAAGTGGCCTTGACAGAAATTTACAAATACATCGTAAAATATTTT
GATGAGATTCTAAATAAACTAGAAAGAGAACGAGGGCTGGAAGAAGCTCAGAAACAACTCTTGCATGTAAAAGTCTTATTTGATGAAAAG
AAGAAATGCAAGTGGATGTAAGCACTCTGGGGCCTGGCTTAATCTGGCAAAGTTCTTCAGACGACTTGGGAGCAAAATGGCTGCTTGAGC
TACTCTGTGTCGTTAATTTGTTGTTTGCACATAGGTTCCACTTTGGGCACTGTCTTTTTAAGAGACCAAGGCACATGCACAGCTTTTAGA
AAGCATACCAACCCTTGTGCCTGTGTGTATACCGTGGGAACCCTTCTGTAAATAGAGTTGAAGTGGTTGTTGCAAACAGCCTCCTTGTTT
ACAGAGAATACAAGGCCAGTAAGCGAATGTCAGTATTGTAACTACAGTCTCCACTTAAGCACAATGATATAAGTGGTTTTGTTTGAAAAC
TACAGCTATGTAGCACTTGTGCTACACTGCACCTCTGCATTGTAAAGGGATACTGCCAGTGCTCAAAACAAAATGTGAAATGAGTCATTT
GGAAACAAGGTGGGGGTGTTAGGGCAACCTCGAGGATTTGCAGCATTGAAACTTTCCCCAGTAGTTCTTGGAAAAGCTGACCGCAGAATT
TGGTAGTGTACACTTAGCATTTGTGAGTGTGTGTGTGTGTTTAAACCAAAAACTAACAGTGTTGCAACATTGTTGAAAGGGCTCGTGTTT
TTCAGTGGTCATCAACTGCACTCCATCAAACTCACCTCCATTTCACCAAGGAGCTCTAAAGTAAGGAGAGTGGGCTTTATTTAAATGAAC
AGCATTTTAACCAGATACTTTGTCCTAATGTATGTTCCTTTTCTTCATCTGTTTTTTCATACTAAATGTATTTGATAGTGGACATGTTGG
ATATTATACAAAAAAATCATTAATTCATTTCTGTTCCAAAACCTTTGATCAGAACGATCTGTGGAAGAGTAACTCCATTTCTATATGAGT
GAGTGTCTCCTTGCTTTAGATTTCTGGTGAACCCTGTGGTTATGAATACTTGTGTGTGATTTAAAAAAAAAAAGATACATTTTACATTTT
ATCGAATTGCTGTTCACACTGGAGTATTATATATAAATATATATATTTGAGGCCCAAGGCCTGAAAAATATTAGTATACAACTTGGTATC
TTAGTCTTACTATGTACTTTTTGAAAGTATTCCTCGCAGGAGAAAGAATTTAAAATACCCATTTTATTCATGCCTTTCTTTTTAAAGAAT
TCTCTATCCAGTTATACTGTAGTCTTTTTAGTGCTGATTTTTTAATTCCTGAATTTTTGCTGCTCATGACCAGTTTTAATACCACTGTGT
TTTCCTTCTATTAAACCAGAAGAAGTAAACAGCATAATTGGCAACTCTTGAGCTTTTCTTGTGGCAGGCACCTTTTACCCTTGGTGCTCC
AAATCCCCCATCTAGGAAAGAAAATTTTTTCAAGTCAAATAACATTGATCACATATTCCTTGAAATCATTTACCAACACTGTATGGAGCA
TTAGGATTTAAATATGAATTTGTCTTAAAGGCAATTCCTTTTTGCTTCTGTATTATCTGGAAAAGCATGAGAGAGGTGACACCTCAACAA
ACTGATCAGAGAAAATAAGCAGTTACTACCCTGATAGGCACCTTCCCAATCCTGTTGCTTTTGACCATTGTCTGTCCAACGGACACACCT
CAAACAAACAAAACTACCAAATAGATGACAGATCAGAATAAAGGTGAGAGGTCTGGTCCCCATTGAAGGCTGCTACAGTCTTCAAAGAGG
TGAAGGAGTTCATAAGAGAACAACAGTAGGAAAGTTGAGAGCCAAGGGTAGGAGAGTTGCCCAAAAGACTTCCCCTACTACTTTAGGGTA
CTGAAAACTCAAAGGATCAGCTACAGCTTTATCTAAGTATTTACTAAATGCTACATGAGGGTGTCCCTGTCCAGCTTTCTGGCACATGAG
TCCTGTGTGGAGAGTTACCTCCTCTTCCAGGGACTGTGCTGTTGGGAACTTTGGGCAAGTCACTTACCTCTTTGTGCCTCAATTTCTGTA
TAATATTTCTAAGCTACCTCACTGAGGTGGTATGAAGATTCACTAATGTATGTAGCGTGTTTGTCAATCCTCCAGTGAAAAGCACTATCT
AGATCACATTTTGGATCACATTAGCCAAATGCAGTAAATGGCCAAATTAGATGTGTGCTGAAGACAATCAGTCACTGGGTCTATATTAAA
CAGCAACCAGAGCAACAAATGGCAAACAATTTCTATTTTCAAGTTTCTTTGCATATTTTTTTGGTGCAAAACCATTTATAAACTTTTTTT
TCTAACACTAGTGTCTACAGCAGCATTCAAAAAAATTCTGTTACCTTTTCTGTATTAGGATTTAAAGTCTATTTCTTATTGTATACCTGA

>33639_33639_1_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000265620_PLXNC1_chr12_94642003_ENST00000258526_length(amino acids)=640AA_BP=
MGNLELYVEQESVPSTWYFLIVLPVLLVIVIFAAVGVTRHKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDY
KHFALRTFFPESGGFTHIFTEDMHNRDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEV
LTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFST
VALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDGITKLNT
IGHYEISNGSTIKVFKKIANFTSDVEYSDDHCHLILPDSEAFQDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNS
RAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNK
LLYAKDIPTYKEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVL

--------------------------------------------------------------
>33639_33639_2_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000306090_PLXNC1_chr12_94642003_ENST00000258526_length(transcript)=6147nt_BP=1642nt
CAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCGGCCTCGGCTCGAGGGGCG
GGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCCCATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCG
CAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCT
GCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGACAGTGA
GAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGT
GGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTA
TGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTA
CTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAAT
CTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTG
CTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCA
GGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCT
CGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGA
GCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCA
CTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCA
CCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTA
CAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCA
GCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAA
AAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATC
AAAATAAAAATTAAATGTGAGCAAAGAAAATGACAACTTCAACATTTCCAAAAAAGACATTGAAATTACTCTCTTCCATGGGGAAAATGG
GCAATTAAATTGCAGTTTTGAAAATATTACTAGAAATCAAGATCTTACCACCATCCTTTGCAAAATTAAAGGCATCAAGACTGCAAGCAC
CATTGCCAACTCTTCTAAGAAAGTTCGGGTCAAGCTGGGAAACCTGGAGCTCTACGTCGAGCAGGAGTCAGTTCCTTCCACATGGTATTT
TCTGATTGTGCTCCCTGTCTTGCTAGTGATTGTCATTTTTGCGGCCGTGGGGGTGACCAGGCACAAATCGAAGGAGCTGAGTCGCAAACA
GAGTCAACAACTAGAATTGCTGGAAAGCGAGCTCCGGAAAGAGATACGTGACGGCTTTGCTGAGCTGCAGATGGATAAATTGGATGTGGT
TGATAGTTTTGGAACTGTTCCCTTCCTTGACTACAAACATTTTGCTCTGAGAACTTTCTTCCCTGAGTCAGGTGGCTTCACCCACATCTT
CACTGAAGATATGCATAACAGAGACGCCAACGACAAGAATGAAAGTCTCACAGCTTTGGATGCCCTAATCTGTAATAAAAGCTTTCTTGT
TACTGTCATCCACACCCTTGAAAAGCAGAAGAACTTTTCTGTGAAGGACAGGTGTCTGTTTGCCTCCTTCCTAACCATTGCACTGCAAAC
CAAGCTGGTCTACCTGACCAGCATCCTAGAGGTGCTGACCAGGGACTTGATGGAACAGTGTAGTAACATGCAGCCGAAACTCATGCTGAG
ACGCACGGAGTCCGTCGTCGAAAAACTCCTCACAAACTGGATGTCCGTCTGCCTTTCTGGATTTCTCCGGGAGACTGTCGGAGAGCCCTT
CTATTTGCTGGTGACGACTCTGAACCAGAAAATTAACAAGGGTCCCGTGGATGTAATCACTTGCAAAGCCCTGTACACACTTAATGAAGA
CTGGCTGTTGTGGCAGGTTCCGGAATTCAGTACTGTGGCATTAAACGTCGTCTTTGAAAAAATCCCGGAAAACGAGAGTGCAGATGTCTG
TCGGAATATTTCAGTCAATGTTCTCGACTGTGACACCATTGGCCAAGCCAAAGAAAAGATTTTCCAAGCATTCTTAAGCAAAAATGGCTC
TCCTTATGGACTTCAGCTTAATGAAATTGGTCTTGAGCTTCAAATGGGCACACGACAGAAAGAACTTCTGGACATCGACAGTTCCTCCGT
GATTCTTGAAGATGGAATCACCAAGCTAAACACCATTGGCCACTATGAGATATCAAATGGATCCACTATAAAAGTCTTTAAGAAGATAGC
AAATTTTACTTCAGATGTGGAGTACTCGGATGACCACTGCCATTTGATTTTACCAGATTCGGAAGCATTCCAAGATGTGCAAGGAAAGAG
ACATCGAGGGAAGCACAAGTTCAAAGTAAAAGAAATGTATCTGACAAAGCTGCTGTCGACCAAGGTGGCAATTCATTCTGTGCTTGAAAA
ACTTTTTAGAAGCATTTGGAGTTTACCCAACAGCAGAGCTCCATTTGCTATAAAATACTTTTTTGACTTTTTGGACGCCCAGGCTGAAAA
CAAAAAAATCACAGATCCTGACGTCGTACATATTTGGAAAACAAACAGCCTTCCTCTTCGCTTCTGGGTAAACATCCTGAAGAACCCTCA
GTTTGTCTTTGACATTAAGAAGACACCACATATAGACGGCTGTTTGTCAGTGATTGCCCAGGCATTCATGGATGCATTTTCTCTCACAGA
GCAGCAACTAGGGAAGGAAGCACCAACTAATAAGCTTCTCTATGCCAAGGATATCCCAACCTACAAAGAAGAAGTAAAATCTTATTACAA
AGCAATCAGGGATTTGCCTCCATTGTCATCCTCAGAAATGGAAGAATTTTTAACTCAGGAATCTAAGAAACATGAAAATGAATTTAATGA
AGAAGTGGCCTTGACAGAAATTTACAAATACATCGTAAAATATTTTGATGAGATTCTAAATAAACTAGAAAGAGAACGAGGGCTGGAAGA
AGCTCAGAAACAACTCTTGCATGTAAAAGTCTTATTTGATGAAAAGAAGAAATGCAAGTGGATGTAAGCACTCTGGGGCCTGGCTTAATC
TGGCAAAGTTCTTCAGACGACTTGGGAGCAAAATGGCTGCTTGAGCTACTCTGTGTCGTTAATTTGTTGTTTGCACATAGGTTCCACTTT
GGGCACTGTCTTTTTAAGAGACCAAGGCACATGCACAGCTTTTAGAAAGCATACCAACCCTTGTGCCTGTGTGTATACCGTGGGAACCCT
TCTGTAAATAGAGTTGAAGTGGTTGTTGCAAACAGCCTCCTTGTTTACAGAGAATACAAGGCCAGTAAGCGAATGTCAGTATTGTAACTA
CAGTCTCCACTTAAGCACAATGATATAAGTGGTTTTGTTTGAAAACTACAGCTATGTAGCACTTGTGCTACACTGCACCTCTGCATTGTA
AAGGGATACTGCCAGTGCTCAAAACAAAATGTGAAATGAGTCATTTGGAAACAAGGTGGGGGTGTTAGGGCAACCTCGAGGATTTGCAGC
ATTGAAACTTTCCCCAGTAGTTCTTGGAAAAGCTGACCGCAGAATTTGGTAGTGTACACTTAGCATTTGTGAGTGTGTGTGTGTGTTTAA
ACCAAAAACTAACAGTGTTGCAACATTGTTGAAAGGGCTCGTGTTTTTCAGTGGTCATCAACTGCACTCCATCAAACTCACCTCCATTTC
ACCAAGGAGCTCTAAAGTAAGGAGAGTGGGCTTTATTTAAATGAACAGCATTTTAACCAGATACTTTGTCCTAATGTATGTTCCTTTTCT
TCATCTGTTTTTTCATACTAAATGTATTTGATAGTGGACATGTTGGATATTATACAAAAAAATCATTAATTCATTTCTGTTCCAAAACCT
TTGATCAGAACGATCTGTGGAAGAGTAACTCCATTTCTATATGAGTGAGTGTCTCCTTGCTTTAGATTTCTGGTGAACCCTGTGGTTATG
AATACTTGTGTGTGATTTAAAAAAAAAAAGATACATTTTACATTTTATCGAATTGCTGTTCACACTGGAGTATTATATATAAATATATAT
ATTTGAGGCCCAAGGCCTGAAAAATATTAGTATACAACTTGGTATCTTAGTCTTACTATGTACTTTTTGAAAGTATTCCTCGCAGGAGAA
AGAATTTAAAATACCCATTTTATTCATGCCTTTCTTTTTAAAGAATTCTCTATCCAGTTATACTGTAGTCTTTTTAGTGCTGATTTTTTA
ATTCCTGAATTTTTGCTGCTCATGACCAGTTTTAATACCACTGTGTTTTCCTTCTATTAAACCAGAAGAAGTAAACAGCATAATTGGCAA
CTCTTGAGCTTTTCTTGTGGCAGGCACCTTTTACCCTTGGTGCTCCAAATCCCCCATCTAGGAAAGAAAATTTTTTCAAGTCAAATAACA
TTGATCACATATTCCTTGAAATCATTTACCAACACTGTATGGAGCATTAGGATTTAAATATGAATTTGTCTTAAAGGCAATTCCTTTTTG
CTTCTGTATTATCTGGAAAAGCATGAGAGAGGTGACACCTCAACAAACTGATCAGAGAAAATAAGCAGTTACTACCCTGATAGGCACCTT
CCCAATCCTGTTGCTTTTGACCATTGTCTGTCCAACGGACACACCTCAAACAAACAAAACTACCAAATAGATGACAGATCAGAATAAAGG
TGAGAGGTCTGGTCCCCATTGAAGGCTGCTACAGTCTTCAAAGAGGTGAAGGAGTTCATAAGAGAACAACAGTAGGAAAGTTGAGAGCCA
AGGGTAGGAGAGTTGCCCAAAAGACTTCCCCTACTACTTTAGGGTACTGAAAACTCAAAGGATCAGCTACAGCTTTATCTAAGTATTTAC
TAAATGCTACATGAGGGTGTCCCTGTCCAGCTTTCTGGCACATGAGTCCTGTGTGGAGAGTTACCTCCTCTTCCAGGGACTGTGCTGTTG
GGAACTTTGGGCAAGTCACTTACCTCTTTGTGCCTCAATTTCTGTATAATATTTCTAAGCTACCTCACTGAGGTGGTATGAAGATTCACT
AATGTATGTAGCGTGTTTGTCAATCCTCCAGTGAAAAGCACTATCTAGATCACATTTTGGATCACATTAGCCAAATGCAGTAAATGGCCA
AATTAGATGTGTGCTGAAGACAATCAGTCACTGGGTCTATATTAAACAGCAACCAGAGCAACAAATGGCAAACAATTTCTATTTTCAAGT
TTCTTTGCATATTTTTTTGGTGCAAAACCATTTATAAACTTTTTTTTCTAACACTAGTGTCTACAGCAGCATTCAAAAAAATTCTGTTAC
CTTTTCTGTATTAGGATTTAAAGTCTATTTCTTATTGTATACCTGATTGAAGCTGTTCTTGGAGATGAATGTTTTAAATGTCTATATCCA

>33639_33639_2_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000306090_PLXNC1_chr12_94642003_ENST00000258526_length(amino acids)=640AA_BP=
MGNLELYVEQESVPSTWYFLIVLPVLLVIVIFAAVGVTRHKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDY
KHFALRTFFPESGGFTHIFTEDMHNRDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEV
LTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFST
VALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDGITKLNT
IGHYEISNGSTIKVFKKIANFTSDVEYSDDHCHLILPDSEAFQDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNS
RAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNK
LLYAKDIPTYKEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVL

--------------------------------------------------------------
>33639_33639_3_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000354359_PLXNC1_chr12_94642003_ENST00000258526_length(transcript)=6480nt_BP=1975nt
TCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCAA
TAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCG
GCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCGC
GGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCCG
CGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGAC
CGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGC
CACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAA
TGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCAGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAA
CCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGT
GGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGG
AGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGC
TGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAA
CTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGT
GGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAA
CAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGAT
TGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAA
GTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGA
CACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAA
CCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATT
AACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTA
AGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAA
ATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGA
AAATGACAACTTCAACATTTCCAAAAAAGACATTGAAATTACTCTCTTCCATGGGGAAAATGGGCAATTAAATTGCAGTTTTGAAAATAT
TACTAGAAATCAAGATCTTACCACCATCCTTTGCAAAATTAAAGGCATCAAGACTGCAAGCACCATTGCCAACTCTTCTAAGAAAGTTCG
GGTCAAGCTGGGAAACCTGGAGCTCTACGTCGAGCAGGAGTCAGTTCCTTCCACATGGTATTTTCTGATTGTGCTCCCTGTCTTGCTAGT
GATTGTCATTTTTGCGGCCGTGGGGGTGACCAGGCACAAATCGAAGGAGCTGAGTCGCAAACAGAGTCAACAACTAGAATTGCTGGAAAG
CGAGCTCCGGAAAGAGATACGTGACGGCTTTGCTGAGCTGCAGATGGATAAATTGGATGTGGTTGATAGTTTTGGAACTGTTCCCTTCCT
TGACTACAAACATTTTGCTCTGAGAACTTTCTTCCCTGAGTCAGGTGGCTTCACCCACATCTTCACTGAAGATATGCATAACAGAGACGC
CAACGACAAGAATGAAAGTCTCACAGCTTTGGATGCCCTAATCTGTAATAAAAGCTTTCTTGTTACTGTCATCCACACCCTTGAAAAGCA
GAAGAACTTTTCTGTGAAGGACAGGTGTCTGTTTGCCTCCTTCCTAACCATTGCACTGCAAACCAAGCTGGTCTACCTGACCAGCATCCT
AGAGGTGCTGACCAGGGACTTGATGGAACAGTGTAGTAACATGCAGCCGAAACTCATGCTGAGACGCACGGAGTCCGTCGTCGAAAAACT
CCTCACAAACTGGATGTCCGTCTGCCTTTCTGGATTTCTCCGGGAGACTGTCGGAGAGCCCTTCTATTTGCTGGTGACGACTCTGAACCA
GAAAATTAACAAGGGTCCCGTGGATGTAATCACTTGCAAAGCCCTGTACACACTTAATGAAGACTGGCTGTTGTGGCAGGTTCCGGAATT
CAGTACTGTGGCATTAAACGTCGTCTTTGAAAAAATCCCGGAAAACGAGAGTGCAGATGTCTGTCGGAATATTTCAGTCAATGTTCTCGA
CTGTGACACCATTGGCCAAGCCAAAGAAAAGATTTTCCAAGCATTCTTAAGCAAAAATGGCTCTCCTTATGGACTTCAGCTTAATGAAAT
TGGTCTTGAGCTTCAAATGGGCACACGACAGAAAGAACTTCTGGACATCGACAGTTCCTCCGTGATTCTTGAAGATGGAATCACCAAGCT
AAACACCATTGGCCACTATGAGATATCAAATGGATCCACTATAAAAGTCTTTAAGAAGATAGCAAATTTTACTTCAGATGTGGAGTACTC
GGATGACCACTGCCATTTGATTTTACCAGATTCGGAAGCATTCCAAGATGTGCAAGGAAAGAGACATCGAGGGAAGCACAAGTTCAAAGT
AAAAGAAATGTATCTGACAAAGCTGCTGTCGACCAAGGTGGCAATTCATTCTGTGCTTGAAAAACTTTTTAGAAGCATTTGGAGTTTACC
CAACAGCAGAGCTCCATTTGCTATAAAATACTTTTTTGACTTTTTGGACGCCCAGGCTGAAAACAAAAAAATCACAGATCCTGACGTCGT
ACATATTTGGAAAACAAACAGCCTTCCTCTTCGCTTCTGGGTAAACATCCTGAAGAACCCTCAGTTTGTCTTTGACATTAAGAAGACACC
ACATATAGACGGCTGTTTGTCAGTGATTGCCCAGGCATTCATGGATGCATTTTCTCTCACAGAGCAGCAACTAGGGAAGGAAGCACCAAC
TAATAAGCTTCTCTATGCCAAGGATATCCCAACCTACAAAGAAGAAGTAAAATCTTATTACAAAGCAATCAGGGATTTGCCTCCATTGTC
ATCCTCAGAAATGGAAGAATTTTTAACTCAGGAATCTAAGAAACATGAAAATGAATTTAATGAAGAAGTGGCCTTGACAGAAATTTACAA
ATACATCGTAAAATATTTTGATGAGATTCTAAATAAACTAGAAAGAGAACGAGGGCTGGAAGAAGCTCAGAAACAACTCTTGCATGTAAA
AGTCTTATTTGATGAAAAGAAGAAATGCAAGTGGATGTAAGCACTCTGGGGCCTGGCTTAATCTGGCAAAGTTCTTCAGACGACTTGGGA
GCAAAATGGCTGCTTGAGCTACTCTGTGTCGTTAATTTGTTGTTTGCACATAGGTTCCACTTTGGGCACTGTCTTTTTAAGAGACCAAGG
CACATGCACAGCTTTTAGAAAGCATACCAACCCTTGTGCCTGTGTGTATACCGTGGGAACCCTTCTGTAAATAGAGTTGAAGTGGTTGTT
GCAAACAGCCTCCTTGTTTACAGAGAATACAAGGCCAGTAAGCGAATGTCAGTATTGTAACTACAGTCTCCACTTAAGCACAATGATATA
AGTGGTTTTGTTTGAAAACTACAGCTATGTAGCACTTGTGCTACACTGCACCTCTGCATTGTAAAGGGATACTGCCAGTGCTCAAAACAA
AATGTGAAATGAGTCATTTGGAAACAAGGTGGGGGTGTTAGGGCAACCTCGAGGATTTGCAGCATTGAAACTTTCCCCAGTAGTTCTTGG
AAAAGCTGACCGCAGAATTTGGTAGTGTACACTTAGCATTTGTGAGTGTGTGTGTGTGTTTAAACCAAAAACTAACAGTGTTGCAACATT
GTTGAAAGGGCTCGTGTTTTTCAGTGGTCATCAACTGCACTCCATCAAACTCACCTCCATTTCACCAAGGAGCTCTAAAGTAAGGAGAGT
GGGCTTTATTTAAATGAACAGCATTTTAACCAGATACTTTGTCCTAATGTATGTTCCTTTTCTTCATCTGTTTTTTCATACTAAATGTAT
TTGATAGTGGACATGTTGGATATTATACAAAAAAATCATTAATTCATTTCTGTTCCAAAACCTTTGATCAGAACGATCTGTGGAAGAGTA
ACTCCATTTCTATATGAGTGAGTGTCTCCTTGCTTTAGATTTCTGGTGAACCCTGTGGTTATGAATACTTGTGTGTGATTTAAAAAAAAA
AAGATACATTTTACATTTTATCGAATTGCTGTTCACACTGGAGTATTATATATAAATATATATATTTGAGGCCCAAGGCCTGAAAAATAT
TAGTATACAACTTGGTATCTTAGTCTTACTATGTACTTTTTGAAAGTATTCCTCGCAGGAGAAAGAATTTAAAATACCCATTTTATTCAT
GCCTTTCTTTTTAAAGAATTCTCTATCCAGTTATACTGTAGTCTTTTTAGTGCTGATTTTTTAATTCCTGAATTTTTGCTGCTCATGACC
AGTTTTAATACCACTGTGTTTTCCTTCTATTAAACCAGAAGAAGTAAACAGCATAATTGGCAACTCTTGAGCTTTTCTTGTGGCAGGCAC
CTTTTACCCTTGGTGCTCCAAATCCCCCATCTAGGAAAGAAAATTTTTTCAAGTCAAATAACATTGATCACATATTCCTTGAAATCATTT
ACCAACACTGTATGGAGCATTAGGATTTAAATATGAATTTGTCTTAAAGGCAATTCCTTTTTGCTTCTGTATTATCTGGAAAAGCATGAG
AGAGGTGACACCTCAACAAACTGATCAGAGAAAATAAGCAGTTACTACCCTGATAGGCACCTTCCCAATCCTGTTGCTTTTGACCATTGT
CTGTCCAACGGACACACCTCAAACAAACAAAACTACCAAATAGATGACAGATCAGAATAAAGGTGAGAGGTCTGGTCCCCATTGAAGGCT
GCTACAGTCTTCAAAGAGGTGAAGGAGTTCATAAGAGAACAACAGTAGGAAAGTTGAGAGCCAAGGGTAGGAGAGTTGCCCAAAAGACTT
CCCCTACTACTTTAGGGTACTGAAAACTCAAAGGATCAGCTACAGCTTTATCTAAGTATTTACTAAATGCTACATGAGGGTGTCCCTGTC
CAGCTTTCTGGCACATGAGTCCTGTGTGGAGAGTTACCTCCTCTTCCAGGGACTGTGCTGTTGGGAACTTTGGGCAAGTCACTTACCTCT
TTGTGCCTCAATTTCTGTATAATATTTCTAAGCTACCTCACTGAGGTGGTATGAAGATTCACTAATGTATGTAGCGTGTTTGTCAATCCT
CCAGTGAAAAGCACTATCTAGATCACATTTTGGATCACATTAGCCAAATGCAGTAAATGGCCAAATTAGATGTGTGCTGAAGACAATCAG
TCACTGGGTCTATATTAAACAGCAACCAGAGCAACAAATGGCAAACAATTTCTATTTTCAAGTTTCTTTGCATATTTTTTTGGTGCAAAA
CCATTTATAAACTTTTTTTTCTAACACTAGTGTCTACAGCAGCATTCAAAAAAATTCTGTTACCTTTTCTGTATTAGGATTTAAAGTCTA
TTTCTTATTGTATACCTGATTGAAGCTGTTCTTGGAGATGAATGTTTTAAATGTCTATATCCAAAAAATAAACATTTTGATGTAACTGTG

>33639_33639_3_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000354359_PLXNC1_chr12_94642003_ENST00000258526_length(amino acids)=640AA_BP=
MGNLELYVEQESVPSTWYFLIVLPVLLVIVIFAAVGVTRHKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDY
KHFALRTFFPESGGFTHIFTEDMHNRDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEV
LTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFST
VALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDGITKLNT
IGHYEISNGSTIKVFKKIANFTSDVEYSDDHCHLILPDSEAFQDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNS
RAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNK
LLYAKDIPTYKEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVL

--------------------------------------------------------------
>33639_33639_4_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000371085_PLXNC1_chr12_94642003_ENST00000258526_length(transcript)=6477nt_BP=1972nt
TCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCAA
TAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCG
GCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCGC
GGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCCG
CGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGAC
CGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGC
CACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAA
TGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCT
GAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGA
CTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGT
GCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGA
CTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTT
CCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGC
CAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAA
CAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGA
GGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTA
CTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACAC
TGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCC
CCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAAC
AAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGG
CGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATG
AAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAA
TGACAACTTCAACATTTCCAAAAAAGACATTGAAATTACTCTCTTCCATGGGGAAAATGGGCAATTAAATTGCAGTTTTGAAAATATTAC
TAGAAATCAAGATCTTACCACCATCCTTTGCAAAATTAAAGGCATCAAGACTGCAAGCACCATTGCCAACTCTTCTAAGAAAGTTCGGGT
CAAGCTGGGAAACCTGGAGCTCTACGTCGAGCAGGAGTCAGTTCCTTCCACATGGTATTTTCTGATTGTGCTCCCTGTCTTGCTAGTGAT
TGTCATTTTTGCGGCCGTGGGGGTGACCAGGCACAAATCGAAGGAGCTGAGTCGCAAACAGAGTCAACAACTAGAATTGCTGGAAAGCGA
GCTCCGGAAAGAGATACGTGACGGCTTTGCTGAGCTGCAGATGGATAAATTGGATGTGGTTGATAGTTTTGGAACTGTTCCCTTCCTTGA
CTACAAACATTTTGCTCTGAGAACTTTCTTCCCTGAGTCAGGTGGCTTCACCCACATCTTCACTGAAGATATGCATAACAGAGACGCCAA
CGACAAGAATGAAAGTCTCACAGCTTTGGATGCCCTAATCTGTAATAAAAGCTTTCTTGTTACTGTCATCCACACCCTTGAAAAGCAGAA
GAACTTTTCTGTGAAGGACAGGTGTCTGTTTGCCTCCTTCCTAACCATTGCACTGCAAACCAAGCTGGTCTACCTGACCAGCATCCTAGA
GGTGCTGACCAGGGACTTGATGGAACAGTGTAGTAACATGCAGCCGAAACTCATGCTGAGACGCACGGAGTCCGTCGTCGAAAAACTCCT
CACAAACTGGATGTCCGTCTGCCTTTCTGGATTTCTCCGGGAGACTGTCGGAGAGCCCTTCTATTTGCTGGTGACGACTCTGAACCAGAA
AATTAACAAGGGTCCCGTGGATGTAATCACTTGCAAAGCCCTGTACACACTTAATGAAGACTGGCTGTTGTGGCAGGTTCCGGAATTCAG
TACTGTGGCATTAAACGTCGTCTTTGAAAAAATCCCGGAAAACGAGAGTGCAGATGTCTGTCGGAATATTTCAGTCAATGTTCTCGACTG
TGACACCATTGGCCAAGCCAAAGAAAAGATTTTCCAAGCATTCTTAAGCAAAAATGGCTCTCCTTATGGACTTCAGCTTAATGAAATTGG
TCTTGAGCTTCAAATGGGCACACGACAGAAAGAACTTCTGGACATCGACAGTTCCTCCGTGATTCTTGAAGATGGAATCACCAAGCTAAA
CACCATTGGCCACTATGAGATATCAAATGGATCCACTATAAAAGTCTTTAAGAAGATAGCAAATTTTACTTCAGATGTGGAGTACTCGGA
TGACCACTGCCATTTGATTTTACCAGATTCGGAAGCATTCCAAGATGTGCAAGGAAAGAGACATCGAGGGAAGCACAAGTTCAAAGTAAA
AGAAATGTATCTGACAAAGCTGCTGTCGACCAAGGTGGCAATTCATTCTGTGCTTGAAAAACTTTTTAGAAGCATTTGGAGTTTACCCAA
CAGCAGAGCTCCATTTGCTATAAAATACTTTTTTGACTTTTTGGACGCCCAGGCTGAAAACAAAAAAATCACAGATCCTGACGTCGTACA
TATTTGGAAAACAAACAGCCTTCCTCTTCGCTTCTGGGTAAACATCCTGAAGAACCCTCAGTTTGTCTTTGACATTAAGAAGACACCACA
TATAGACGGCTGTTTGTCAGTGATTGCCCAGGCATTCATGGATGCATTTTCTCTCACAGAGCAGCAACTAGGGAAGGAAGCACCAACTAA
TAAGCTTCTCTATGCCAAGGATATCCCAACCTACAAAGAAGAAGTAAAATCTTATTACAAAGCAATCAGGGATTTGCCTCCATTGTCATC
CTCAGAAATGGAAGAATTTTTAACTCAGGAATCTAAGAAACATGAAAATGAATTTAATGAAGAAGTGGCCTTGACAGAAATTTACAAATA
CATCGTAAAATATTTTGATGAGATTCTAAATAAACTAGAAAGAGAACGAGGGCTGGAAGAAGCTCAGAAACAACTCTTGCATGTAAAAGT
CTTATTTGATGAAAAGAAGAAATGCAAGTGGATGTAAGCACTCTGGGGCCTGGCTTAATCTGGCAAAGTTCTTCAGACGACTTGGGAGCA
AAATGGCTGCTTGAGCTACTCTGTGTCGTTAATTTGTTGTTTGCACATAGGTTCCACTTTGGGCACTGTCTTTTTAAGAGACCAAGGCAC
ATGCACAGCTTTTAGAAAGCATACCAACCCTTGTGCCTGTGTGTATACCGTGGGAACCCTTCTGTAAATAGAGTTGAAGTGGTTGTTGCA
AACAGCCTCCTTGTTTACAGAGAATACAAGGCCAGTAAGCGAATGTCAGTATTGTAACTACAGTCTCCACTTAAGCACAATGATATAAGT
GGTTTTGTTTGAAAACTACAGCTATGTAGCACTTGTGCTACACTGCACCTCTGCATTGTAAAGGGATACTGCCAGTGCTCAAAACAAAAT
GTGAAATGAGTCATTTGGAAACAAGGTGGGGGTGTTAGGGCAACCTCGAGGATTTGCAGCATTGAAACTTTCCCCAGTAGTTCTTGGAAA
AGCTGACCGCAGAATTTGGTAGTGTACACTTAGCATTTGTGAGTGTGTGTGTGTGTTTAAACCAAAAACTAACAGTGTTGCAACATTGTT
GAAAGGGCTCGTGTTTTTCAGTGGTCATCAACTGCACTCCATCAAACTCACCTCCATTTCACCAAGGAGCTCTAAAGTAAGGAGAGTGGG
CTTTATTTAAATGAACAGCATTTTAACCAGATACTTTGTCCTAATGTATGTTCCTTTTCTTCATCTGTTTTTTCATACTAAATGTATTTG
ATAGTGGACATGTTGGATATTATACAAAAAAATCATTAATTCATTTCTGTTCCAAAACCTTTGATCAGAACGATCTGTGGAAGAGTAACT
CCATTTCTATATGAGTGAGTGTCTCCTTGCTTTAGATTTCTGGTGAACCCTGTGGTTATGAATACTTGTGTGTGATTTAAAAAAAAAAAG
ATACATTTTACATTTTATCGAATTGCTGTTCACACTGGAGTATTATATATAAATATATATATTTGAGGCCCAAGGCCTGAAAAATATTAG
TATACAACTTGGTATCTTAGTCTTACTATGTACTTTTTGAAAGTATTCCTCGCAGGAGAAAGAATTTAAAATACCCATTTTATTCATGCC
TTTCTTTTTAAAGAATTCTCTATCCAGTTATACTGTAGTCTTTTTAGTGCTGATTTTTTAATTCCTGAATTTTTGCTGCTCATGACCAGT
TTTAATACCACTGTGTTTTCCTTCTATTAAACCAGAAGAAGTAAACAGCATAATTGGCAACTCTTGAGCTTTTCTTGTGGCAGGCACCTT
TTACCCTTGGTGCTCCAAATCCCCCATCTAGGAAAGAAAATTTTTTCAAGTCAAATAACATTGATCACATATTCCTTGAAATCATTTACC
AACACTGTATGGAGCATTAGGATTTAAATATGAATTTGTCTTAAAGGCAATTCCTTTTTGCTTCTGTATTATCTGGAAAAGCATGAGAGA
GGTGACACCTCAACAAACTGATCAGAGAAAATAAGCAGTTACTACCCTGATAGGCACCTTCCCAATCCTGTTGCTTTTGACCATTGTCTG
TCCAACGGACACACCTCAAACAAACAAAACTACCAAATAGATGACAGATCAGAATAAAGGTGAGAGGTCTGGTCCCCATTGAAGGCTGCT
ACAGTCTTCAAAGAGGTGAAGGAGTTCATAAGAGAACAACAGTAGGAAAGTTGAGAGCCAAGGGTAGGAGAGTTGCCCAAAAGACTTCCC
CTACTACTTTAGGGTACTGAAAACTCAAAGGATCAGCTACAGCTTTATCTAAGTATTTACTAAATGCTACATGAGGGTGTCCCTGTCCAG
CTTTCTGGCACATGAGTCCTGTGTGGAGAGTTACCTCCTCTTCCAGGGACTGTGCTGTTGGGAACTTTGGGCAAGTCACTTACCTCTTTG
TGCCTCAATTTCTGTATAATATTTCTAAGCTACCTCACTGAGGTGGTATGAAGATTCACTAATGTATGTAGCGTGTTTGTCAATCCTCCA
GTGAAAAGCACTATCTAGATCACATTTTGGATCACATTAGCCAAATGCAGTAAATGGCCAAATTAGATGTGTGCTGAAGACAATCAGTCA
CTGGGTCTATATTAAACAGCAACCAGAGCAACAAATGGCAAACAATTTCTATTTTCAAGTTTCTTTGCATATTTTTTTGGTGCAAAACCA
TTTATAAACTTTTTTTTCTAACACTAGTGTCTACAGCAGCATTCAAAAAAATTCTGTTACCTTTTCTGTATTAGGATTTAAAGTCTATTT

>33639_33639_4_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000371085_PLXNC1_chr12_94642003_ENST00000258526_length(amino acids)=640AA_BP=
MGNLELYVEQESVPSTWYFLIVLPVLLVIVIFAAVGVTRHKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDY
KHFALRTFFPESGGFTHIFTEDMHNRDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEV
LTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFST
VALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDGITKLNT
IGHYEISNGSTIKVFKKIANFTSDVEYSDDHCHLILPDSEAFQDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNS
RAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNK
LLYAKDIPTYKEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVL

--------------------------------------------------------------
>33639_33639_5_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000371095_PLXNC1_chr12_94642003_ENST00000258526_length(transcript)=6436nt_BP=1931nt
CTCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCA
ATAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTC
GGCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCG
CGGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCC
GCGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGA
CCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGG
CCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTA
ATGGAGACAGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACC
TGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCC
CTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTG
ACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCC
TGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCA
AGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGA
CCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACA
AGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGG
ATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTG
GAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCA
TTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTG
AAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCC
CCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTC
TCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGC
ATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAATGACAACTTCAACATTTCCAAAAAAGACATTGAAATTACTC
TCTTCCATGGGGAAAATGGGCAATTAAATTGCAGTTTTGAAAATATTACTAGAAATCAAGATCTTACCACCATCCTTTGCAAAATTAAAG
GCATCAAGACTGCAAGCACCATTGCCAACTCTTCTAAGAAAGTTCGGGTCAAGCTGGGAAACCTGGAGCTCTACGTCGAGCAGGAGTCAG
TTCCTTCCACATGGTATTTTCTGATTGTGCTCCCTGTCTTGCTAGTGATTGTCATTTTTGCGGCCGTGGGGGTGACCAGGCACAAATCGA
AGGAGCTGAGTCGCAAACAGAGTCAACAACTAGAATTGCTGGAAAGCGAGCTCCGGAAAGAGATACGTGACGGCTTTGCTGAGCTGCAGA
TGGATAAATTGGATGTGGTTGATAGTTTTGGAACTGTTCCCTTCCTTGACTACAAACATTTTGCTCTGAGAACTTTCTTCCCTGAGTCAG
GTGGCTTCACCCACATCTTCACTGAAGATATGCATAACAGAGACGCCAACGACAAGAATGAAAGTCTCACAGCTTTGGATGCCCTAATCT
GTAATAAAAGCTTTCTTGTTACTGTCATCCACACCCTTGAAAAGCAGAAGAACTTTTCTGTGAAGGACAGGTGTCTGTTTGCCTCCTTCC
TAACCATTGCACTGCAAACCAAGCTGGTCTACCTGACCAGCATCCTAGAGGTGCTGACCAGGGACTTGATGGAACAGTGTAGTAACATGC
AGCCGAAACTCATGCTGAGACGCACGGAGTCCGTCGTCGAAAAACTCCTCACAAACTGGATGTCCGTCTGCCTTTCTGGATTTCTCCGGG
AGACTGTCGGAGAGCCCTTCTATTTGCTGGTGACGACTCTGAACCAGAAAATTAACAAGGGTCCCGTGGATGTAATCACTTGCAAAGCCC
TGTACACACTTAATGAAGACTGGCTGTTGTGGCAGGTTCCGGAATTCAGTACTGTGGCATTAAACGTCGTCTTTGAAAAAATCCCGGAAA
ACGAGAGTGCAGATGTCTGTCGGAATATTTCAGTCAATGTTCTCGACTGTGACACCATTGGCCAAGCCAAAGAAAAGATTTTCCAAGCAT
TCTTAAGCAAAAATGGCTCTCCTTATGGACTTCAGCTTAATGAAATTGGTCTTGAGCTTCAAATGGGCACACGACAGAAAGAACTTCTGG
ACATCGACAGTTCCTCCGTGATTCTTGAAGATGGAATCACCAAGCTAAACACCATTGGCCACTATGAGATATCAAATGGATCCACTATAA
AAGTCTTTAAGAAGATAGCAAATTTTACTTCAGATGTGGAGTACTCGGATGACCACTGCCATTTGATTTTACCAGATTCGGAAGCATTCC
AAGATGTGCAAGGAAAGAGACATCGAGGGAAGCACAAGTTCAAAGTAAAAGAAATGTATCTGACAAAGCTGCTGTCGACCAAGGTGGCAA
TTCATTCTGTGCTTGAAAAACTTTTTAGAAGCATTTGGAGTTTACCCAACAGCAGAGCTCCATTTGCTATAAAATACTTTTTTGACTTTT
TGGACGCCCAGGCTGAAAACAAAAAAATCACAGATCCTGACGTCGTACATATTTGGAAAACAAACAGCCTTCCTCTTCGCTTCTGGGTAA
ACATCCTGAAGAACCCTCAGTTTGTCTTTGACATTAAGAAGACACCACATATAGACGGCTGTTTGTCAGTGATTGCCCAGGCATTCATGG
ATGCATTTTCTCTCACAGAGCAGCAACTAGGGAAGGAAGCACCAACTAATAAGCTTCTCTATGCCAAGGATATCCCAACCTACAAAGAAG
AAGTAAAATCTTATTACAAAGCAATCAGGGATTTGCCTCCATTGTCATCCTCAGAAATGGAAGAATTTTTAACTCAGGAATCTAAGAAAC
ATGAAAATGAATTTAATGAAGAAGTGGCCTTGACAGAAATTTACAAATACATCGTAAAATATTTTGATGAGATTCTAAATAAACTAGAAA
GAGAACGAGGGCTGGAAGAAGCTCAGAAACAACTCTTGCATGTAAAAGTCTTATTTGATGAAAAGAAGAAATGCAAGTGGATGTAAGCAC
TCTGGGGCCTGGCTTAATCTGGCAAAGTTCTTCAGACGACTTGGGAGCAAAATGGCTGCTTGAGCTACTCTGTGTCGTTAATTTGTTGTT
TGCACATAGGTTCCACTTTGGGCACTGTCTTTTTAAGAGACCAAGGCACATGCACAGCTTTTAGAAAGCATACCAACCCTTGTGCCTGTG
TGTATACCGTGGGAACCCTTCTGTAAATAGAGTTGAAGTGGTTGTTGCAAACAGCCTCCTTGTTTACAGAGAATACAAGGCCAGTAAGCG
AATGTCAGTATTGTAACTACAGTCTCCACTTAAGCACAATGATATAAGTGGTTTTGTTTGAAAACTACAGCTATGTAGCACTTGTGCTAC
ACTGCACCTCTGCATTGTAAAGGGATACTGCCAGTGCTCAAAACAAAATGTGAAATGAGTCATTTGGAAACAAGGTGGGGGTGTTAGGGC
AACCTCGAGGATTTGCAGCATTGAAACTTTCCCCAGTAGTTCTTGGAAAAGCTGACCGCAGAATTTGGTAGTGTACACTTAGCATTTGTG
AGTGTGTGTGTGTGTTTAAACCAAAAACTAACAGTGTTGCAACATTGTTGAAAGGGCTCGTGTTTTTCAGTGGTCATCAACTGCACTCCA
TCAAACTCACCTCCATTTCACCAAGGAGCTCTAAAGTAAGGAGAGTGGGCTTTATTTAAATGAACAGCATTTTAACCAGATACTTTGTCC
TAATGTATGTTCCTTTTCTTCATCTGTTTTTTCATACTAAATGTATTTGATAGTGGACATGTTGGATATTATACAAAAAAATCATTAATT
CATTTCTGTTCCAAAACCTTTGATCAGAACGATCTGTGGAAGAGTAACTCCATTTCTATATGAGTGAGTGTCTCCTTGCTTTAGATTTCT
GGTGAACCCTGTGGTTATGAATACTTGTGTGTGATTTAAAAAAAAAAAGATACATTTTACATTTTATCGAATTGCTGTTCACACTGGAGT
ATTATATATAAATATATATATTTGAGGCCCAAGGCCTGAAAAATATTAGTATACAACTTGGTATCTTAGTCTTACTATGTACTTTTTGAA
AGTATTCCTCGCAGGAGAAAGAATTTAAAATACCCATTTTATTCATGCCTTTCTTTTTAAAGAATTCTCTATCCAGTTATACTGTAGTCT
TTTTAGTGCTGATTTTTTAATTCCTGAATTTTTGCTGCTCATGACCAGTTTTAATACCACTGTGTTTTCCTTCTATTAAACCAGAAGAAG
TAAACAGCATAATTGGCAACTCTTGAGCTTTTCTTGTGGCAGGCACCTTTTACCCTTGGTGCTCCAAATCCCCCATCTAGGAAAGAAAAT
TTTTTCAAGTCAAATAACATTGATCACATATTCCTTGAAATCATTTACCAACACTGTATGGAGCATTAGGATTTAAATATGAATTTGTCT
TAAAGGCAATTCCTTTTTGCTTCTGTATTATCTGGAAAAGCATGAGAGAGGTGACACCTCAACAAACTGATCAGAGAAAATAAGCAGTTA
CTACCCTGATAGGCACCTTCCCAATCCTGTTGCTTTTGACCATTGTCTGTCCAACGGACACACCTCAAACAAACAAAACTACCAAATAGA
TGACAGATCAGAATAAAGGTGAGAGGTCTGGTCCCCATTGAAGGCTGCTACAGTCTTCAAAGAGGTGAAGGAGTTCATAAGAGAACAACA
GTAGGAAAGTTGAGAGCCAAGGGTAGGAGAGTTGCCCAAAAGACTTCCCCTACTACTTTAGGGTACTGAAAACTCAAAGGATCAGCTACA
GCTTTATCTAAGTATTTACTAAATGCTACATGAGGGTGTCCCTGTCCAGCTTTCTGGCACATGAGTCCTGTGTGGAGAGTTACCTCCTCT
TCCAGGGACTGTGCTGTTGGGAACTTTGGGCAAGTCACTTACCTCTTTGTGCCTCAATTTCTGTATAATATTTCTAAGCTACCTCACTGA
GGTGGTATGAAGATTCACTAATGTATGTAGCGTGTTTGTCAATCCTCCAGTGAAAAGCACTATCTAGATCACATTTTGGATCACATTAGC
CAAATGCAGTAAATGGCCAAATTAGATGTGTGCTGAAGACAATCAGTCACTGGGTCTATATTAAACAGCAACCAGAGCAACAAATGGCAA
ACAATTTCTATTTTCAAGTTTCTTTGCATATTTTTTTGGTGCAAAACCATTTATAAACTTTTTTTTCTAACACTAGTGTCTACAGCAGCA
TTCAAAAAAATTCTGTTACCTTTTCTGTATTAGGATTTAAAGTCTATTTCTTATTGTATACCTGATTGAAGCTGTTCTTGGAGATGAATG

>33639_33639_5_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000371095_PLXNC1_chr12_94642003_ENST00000258526_length(amino acids)=640AA_BP=
MGNLELYVEQESVPSTWYFLIVLPVLLVIVIFAAVGVTRHKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDY
KHFALRTFFPESGGFTHIFTEDMHNRDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEV
LTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFST
VALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDGITKLNT
IGHYEISNGSTIKVFKKIANFTSDVEYSDDHCHLILPDSEAFQDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNS
RAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNK
LLYAKDIPTYKEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVL

--------------------------------------------------------------
>33639_33639_6_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000371100_PLXNC1_chr12_94642003_ENST00000258526_length(transcript)=8534nt_BP=4029nt
AAAGACTCCAAATCAGTCAGGGAGAGGAGTGGAAGGAGCCAAAACGTCCCTGCGAGGCCTGCGCTCACCAGCCCCCTTACCCAAAGTCCC
GGGCCCCTGGCGCCAGGAGCAGGCTCCTGGAGCCGGAGCCAGCTCGGCACTGGAACCGGCGTCCTCTGGTGGCAGAGAGAGAGCGCTACT
GGCGATTTTCGGACCGAATCGGCACGCTCGTCAGATCCAAGCAGGCGGGACTGGCCTGGAGCAAAAAGAAAGAGAGAGGAGGGCGTAAGG
ATAGACCAAGGAAGAGGGGCTGGGGGGCAGCCTGGGGGCATGAAAAGTGGCCAGGAAGGAGCCAAGACTCCACCAGCAACAATTGAGTTG
CTTCAGCCTCAGTCTAGGGTTCCTTCCAGGCCTTGAACCCCCCAACCTCACAAGGGTTGGAAAGTGAGGCCGGTGAACTTTCCAGCTGGT
ACTTTGATTTTAAAATAATAATAATAATTTTTTCACCCTAGTTCGGTTGGGTGCTCCATCTTACGGAGCCCCAAACTTATTTTGAGAGGC
CGCCACCGTGTTATGGGCGTGCGCAACTGCCTCTACGGCAATAATATGTCAGGACAACGCGATATCCCCCCTGAAATCGGGGAACAGCCC
GAGCAACCACCTTTGGAGGCCCCAGGGGCAGCTGCCCCCGGTGCTGGGCCTAGCCCAGCCGAAGAGATGGAGACCGAACCGCCTCACAAC
GAGCCCATCCCCGTCGAGAATGATGGCGAGGCCTGTGGACCCCCAGAGGTCTCCAGACCCAACTTTCAGGTCCTCAACCCGGCATTCAGG
GAAGCTGGAGCCCATGGAAGCTACAGCCCACCTCCTGAGGAAGCAATGCCCTTCGAGGCTGAACAGCCCAGCTTGGGAGGCTTCTGGCCT
ACACTGGAGCAGCCTGGATTCCCCAGTGGGGTCCATGCAGGCCTTGAGGCCTTCGGCCCAGCACTCATGGAGCCCGGAGCCTTCAGTGGT
GCCAGACCAGGCCTGGGAGGATACAGCCCTCCACCAGAAGAAGCTATGCCCTTTGAGTTTGACCAGCCTGCCCAGAGAGGCTGCAGTCAA
CTTCTCTTACAGGTCCCAGACCTTGCTCCAGGAGGCCCAGGTGCTGCAGGGGTCCCCGGAGCTCCTCCCGAGGAGCCCCAAGCCCTCAGG
CCTGCAAAGGCTGGCTCCAGAGGAGGCTACAGCCCTCCCCCTGAGGAGACTATGCCATTTGAGCTTGATGGAGAAGGATTTGGGGACGAC
AGCCCACCCCCGGGGCTTTCCCGAGTTATCGCACAAGTCGACGGCAGCAGCCAGTTCGCGGCAGTCGCGGCCTCGAGTGCGGTCCGCCTC
ACTCCCGCCGCGAACGCGCCTCCCCTCTGGGTCCCAGGCGCCATCGGCAGCCCATCCCAAGAGGCTGTCAGACCTCCTTCTAACTTCACG
GGCAGCAGCCCCTGGATGGAGATCTCCGGACCCCCGTTCGAGATTGGCAGCGCCCCCGCTGGGGTCGACGACACTCCCGTCAACATGGAC
AGCCCCCCAATCGCGCTTGACGGCCCGCCCATCAAGGTCTCCGGAGCCCCAGATAAGAGAGAGCGAGCAGAGAGACCCCCAGTTGAGGAG
GAAGCAGCAGAGATGGAAGGAGCCGCTGATGCCGCGGAGGGAGGAAAAGTACCCTCTCCGGGGTACGGATCCCCTGCCGCCGGGGCAGCC
TCAGCGGATACCGCTGCCAGGGCAGCCCCTGCAGCCCCAGCCGATCCTGACTCCGGGGCAACCCCAGAAGATCCCGACTCCGGGACAGCA
CCAGCCGATCCTGACTCCGGGGCATTCGCAGCCGATCCCGACTCCGGGGCAGCCCCTGCCGCCCCAGCCGATCCCGACTCCGGGGCGGCC
CCTGACGCCCCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCAGCCGATCCAGATGCCGGGGCGGCCCCTGAGGCTCCCGCCGCC
CCTGCGGCTGCTGAGACCCGGGCAGCCCATGTCGCCCCAGCTGCGCCAGACGCAGGGGCTCCCACTGCCCCAGCCGCTTCTGCCACCCGG
GCAGCCCAAGTCCGCCGGGCGGCCTCTGCAGCCCCTGCCTCCGGGGCCAGACGCAAGATCCATCTCAGACCCCCCAGCCCCGAGATCCAG
GCTGCCGATCCGCCTACTCCGCGGCCTACTCGCGCGTCTGCCTGGCGGGGCAAGTCCGAGAGCAGCCGCGGCCGCCGCGTGTACTACGAT
GAAGGGGTGGCCAGCAGCGACGATGACTCCAGCGGAGACGAGTCCGACGATGGGACCTCCGGATGCCTCCGCTGGTTTCAGCATCGGCGA
AATCGCCGCCGCCGAAAGCCCCAGCGCAACTTACTCCGCAACTTTCTCGTGCAAGCCTTCGGGGGCTGCTTCGGTCGATCTGAGAGTCCC
CAGCCCAAAGCCTCGCGCTCTCTCAAGGTCAAGAAGGTACCCCTGGCGGAGAAGCGCAGACAGATGCGCAAAGAAGCCCTGGAGAAGCGG
GCCCAGAAGCGCGCAGAGAAGAAACGCAGTAAGCTCATCGACAAACAACTCCAGGACGAAAAGATGGGCTACATGTGTACGCACCGCCTG
CTGCTTCTAGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGC
GAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGTGAGAAGGCAACCAAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATT
GAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCCAACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGT
GTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCCAAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTAC
GAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGACAAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGC
GATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACCAAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGAC
GTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGATGTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTAC
AACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTGAACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGC
ACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAAGTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCA
GAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAGGACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGAT
GAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTACCCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGC
CGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAGTACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTA
AAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTAATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTC
CCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAGATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAA
AAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAAAACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAAC
AAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAATTAAATGTGAGCAAAGAAAAAGAAAATGACAACTTCAAC
ATTTCCAAAAAAGACATTGAAATTACTCTCTTCCATGGGGAAAATGGGCAATTAAATTGCAGTTTTGAAAATATTACTAGAAATCAAGAT
CTTACCACCATCCTTTGCAAAATTAAAGGCATCAAGACTGCAAGCACCATTGCCAACTCTTCTAAGAAAGTTCGGGTCAAGCTGGGAAAC
CTGGAGCTCTACGTCGAGCAGGAGTCAGTTCCTTCCACATGGTATTTTCTGATTGTGCTCCCTGTCTTGCTAGTGATTGTCATTTTTGCG
GCCGTGGGGGTGACCAGGCACAAATCGAAGGAGCTGAGTCGCAAACAGAGTCAACAACTAGAATTGCTGGAAAGCGAGCTCCGGAAAGAG
ATACGTGACGGCTTTGCTGAGCTGCAGATGGATAAATTGGATGTGGTTGATAGTTTTGGAACTGTTCCCTTCCTTGACTACAAACATTTT
GCTCTGAGAACTTTCTTCCCTGAGTCAGGTGGCTTCACCCACATCTTCACTGAAGATATGCATAACAGAGACGCCAACGACAAGAATGAA
AGTCTCACAGCTTTGGATGCCCTAATCTGTAATAAAAGCTTTCTTGTTACTGTCATCCACACCCTTGAAAAGCAGAAGAACTTTTCTGTG
AAGGACAGGTGTCTGTTTGCCTCCTTCCTAACCATTGCACTGCAAACCAAGCTGGTCTACCTGACCAGCATCCTAGAGGTGCTGACCAGG
GACTTGATGGAACAGTGTAGTAACATGCAGCCGAAACTCATGCTGAGACGCACGGAGTCCGTCGTCGAAAAACTCCTCACAAACTGGATG
TCCGTCTGCCTTTCTGGATTTCTCCGGGAGACTGTCGGAGAGCCCTTCTATTTGCTGGTGACGACTCTGAACCAGAAAATTAACAAGGGT
CCCGTGGATGTAATCACTTGCAAAGCCCTGTACACACTTAATGAAGACTGGCTGTTGTGGCAGGTTCCGGAATTCAGTACTGTGGCATTA
AACGTCGTCTTTGAAAAAATCCCGGAAAACGAGAGTGCAGATGTCTGTCGGAATATTTCAGTCAATGTTCTCGACTGTGACACCATTGGC
CAAGCCAAAGAAAAGATTTTCCAAGCATTCTTAAGCAAAAATGGCTCTCCTTATGGACTTCAGCTTAATGAAATTGGTCTTGAGCTTCAA
ATGGGCACACGACAGAAAGAACTTCTGGACATCGACAGTTCCTCCGTGATTCTTGAAGATGGAATCACCAAGCTAAACACCATTGGCCAC
TATGAGATATCAAATGGATCCACTATAAAAGTCTTTAAGAAGATAGCAAATTTTACTTCAGATGTGGAGTACTCGGATGACCACTGCCAT
TTGATTTTACCAGATTCGGAAGCATTCCAAGATGTGCAAGGAAAGAGACATCGAGGGAAGCACAAGTTCAAAGTAAAAGAAATGTATCTG
ACAAAGCTGCTGTCGACCAAGGTGGCAATTCATTCTGTGCTTGAAAAACTTTTTAGAAGCATTTGGAGTTTACCCAACAGCAGAGCTCCA
TTTGCTATAAAATACTTTTTTGACTTTTTGGACGCCCAGGCTGAAAACAAAAAAATCACAGATCCTGACGTCGTACATATTTGGAAAACA
AACAGCCTTCCTCTTCGCTTCTGGGTAAACATCCTGAAGAACCCTCAGTTTGTCTTTGACATTAAGAAGACACCACATATAGACGGCTGT
TTGTCAGTGATTGCCCAGGCATTCATGGATGCATTTTCTCTCACAGAGCAGCAACTAGGGAAGGAAGCACCAACTAATAAGCTTCTCTAT
GCCAAGGATATCCCAACCTACAAAGAAGAAGTAAAATCTTATTACAAAGCAATCAGGGATTTGCCTCCATTGTCATCCTCAGAAATGGAA
GAATTTTTAACTCAGGAATCTAAGAAACATGAAAATGAATTTAATGAAGAAGTGGCCTTGACAGAAATTTACAAATACATCGTAAAATAT
TTTGATGAGATTCTAAATAAACTAGAAAGAGAACGAGGGCTGGAAGAAGCTCAGAAACAACTCTTGCATGTAAAAGTCTTATTTGATGAA
AAGAAGAAATGCAAGTGGATGTAAGCACTCTGGGGCCTGGCTTAATCTGGCAAAGTTCTTCAGACGACTTGGGAGCAAAATGGCTGCTTG
AGCTACTCTGTGTCGTTAATTTGTTGTTTGCACATAGGTTCCACTTTGGGCACTGTCTTTTTAAGAGACCAAGGCACATGCACAGCTTTT
AGAAAGCATACCAACCCTTGTGCCTGTGTGTATACCGTGGGAACCCTTCTGTAAATAGAGTTGAAGTGGTTGTTGCAAACAGCCTCCTTG
TTTACAGAGAATACAAGGCCAGTAAGCGAATGTCAGTATTGTAACTACAGTCTCCACTTAAGCACAATGATATAAGTGGTTTTGTTTGAA
AACTACAGCTATGTAGCACTTGTGCTACACTGCACCTCTGCATTGTAAAGGGATACTGCCAGTGCTCAAAACAAAATGTGAAATGAGTCA
TTTGGAAACAAGGTGGGGGTGTTAGGGCAACCTCGAGGATTTGCAGCATTGAAACTTTCCCCAGTAGTTCTTGGAAAAGCTGACCGCAGA
ATTTGGTAGTGTACACTTAGCATTTGTGAGTGTGTGTGTGTGTTTAAACCAAAAACTAACAGTGTTGCAACATTGTTGAAAGGGCTCGTG
TTTTTCAGTGGTCATCAACTGCACTCCATCAAACTCACCTCCATTTCACCAAGGAGCTCTAAAGTAAGGAGAGTGGGCTTTATTTAAATG
AACAGCATTTTAACCAGATACTTTGTCCTAATGTATGTTCCTTTTCTTCATCTGTTTTTTCATACTAAATGTATTTGATAGTGGACATGT
TGGATATTATACAAAAAAATCATTAATTCATTTCTGTTCCAAAACCTTTGATCAGAACGATCTGTGGAAGAGTAACTCCATTTCTATATG
AGTGAGTGTCTCCTTGCTTTAGATTTCTGGTGAACCCTGTGGTTATGAATACTTGTGTGTGATTTAAAAAAAAAAAGATACATTTTACAT
TTTATCGAATTGCTGTTCACACTGGAGTATTATATATAAATATATATATTTGAGGCCCAAGGCCTGAAAAATATTAGTATACAACTTGGT
ATCTTAGTCTTACTATGTACTTTTTGAAAGTATTCCTCGCAGGAGAAAGAATTTAAAATACCCATTTTATTCATGCCTTTCTTTTTAAAG
AATTCTCTATCCAGTTATACTGTAGTCTTTTTAGTGCTGATTTTTTAATTCCTGAATTTTTGCTGCTCATGACCAGTTTTAATACCACTG
TGTTTTCCTTCTATTAAACCAGAAGAAGTAAACAGCATAATTGGCAACTCTTGAGCTTTTCTTGTGGCAGGCACCTTTTACCCTTGGTGC
TCCAAATCCCCCATCTAGGAAAGAAAATTTTTTCAAGTCAAATAACATTGATCACATATTCCTTGAAATCATTTACCAACACTGTATGGA
GCATTAGGATTTAAATATGAATTTGTCTTAAAGGCAATTCCTTTTTGCTTCTGTATTATCTGGAAAAGCATGAGAGAGGTGACACCTCAA
CAAACTGATCAGAGAAAATAAGCAGTTACTACCCTGATAGGCACCTTCCCAATCCTGTTGCTTTTGACCATTGTCTGTCCAACGGACACA
CCTCAAACAAACAAAACTACCAAATAGATGACAGATCAGAATAAAGGTGAGAGGTCTGGTCCCCATTGAAGGCTGCTACAGTCTTCAAAG
AGGTGAAGGAGTTCATAAGAGAACAACAGTAGGAAAGTTGAGAGCCAAGGGTAGGAGAGTTGCCCAAAAGACTTCCCCTACTACTTTAGG
GTACTGAAAACTCAAAGGATCAGCTACAGCTTTATCTAAGTATTTACTAAATGCTACATGAGGGTGTCCCTGTCCAGCTTTCTGGCACAT
GAGTCCTGTGTGGAGAGTTACCTCCTCTTCCAGGGACTGTGCTGTTGGGAACTTTGGGCAAGTCACTTACCTCTTTGTGCCTCAATTTCT
GTATAATATTTCTAAGCTACCTCACTGAGGTGGTATGAAGATTCACTAATGTATGTAGCGTGTTTGTCAATCCTCCAGTGAAAAGCACTA
TCTAGATCACATTTTGGATCACATTAGCCAAATGCAGTAAATGGCCAAATTAGATGTGTGCTGAAGACAATCAGTCACTGGGTCTATATT
AAACAGCAACCAGAGCAACAAATGGCAAACAATTTCTATTTTCAAGTTTCTTTGCATATTTTTTTGGTGCAAAACCATTTATAAACTTTT
TTTTCTAACACTAGTGTCTACAGCAGCATTCAAAAAAATTCTGTTACCTTTTCTGTATTAGGATTTAAAGTCTATTTCTTATTGTATACC

>33639_33639_6_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000371100_PLXNC1_chr12_94642003_ENST00000258526_length(amino acids)=1044AA_BP=
MRGRHRVMGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNP
AFREAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRG
CSQLLLQVPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSA
VRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPP
VEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDS
GAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSP
EIQAADPPTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRS
ESPQPKASRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNG
EGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR
ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVAS
SSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYF

--------------------------------------------------------------
>33639_33639_7_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000371102_PLXNC1_chr12_94642003_ENST00000258526_length(transcript)=7943nt_BP=3438nt
GTTATGGGCGTGCGCAACTGCCTCTACGGCAATAATATGTCAGGACAACGCGATATCCCCCCTGAAATCGGGGAACAGCCCGAGCAACCA
CCTTTGGAGGCCCCAGGGGCAGCTGCCCCCGGTGCTGGGCCTAGCCCAGCCGAAGAGATGGAGACCGAACCGCCTCACAACGAGCCCATC
CCCGTCGAGAATGATGGCGAGGCCTGTGGACCCCCAGAGGTCTCCAGACCCAACTTTCAGGTCCTCAACCCGGCATTCAGGGAAGCTGGA
GCCCATGGAAGCTACAGCCCACCTCCTGAGGAAGCAATGCCCTTCGAGGCTGAACAGCCCAGCTTGGGAGGCTTCTGGCCTACACTGGAG
CAGCCTGGATTCCCCAGTGGGGTCCATGCAGGCCTTGAGGCCTTCGGCCCAGCACTCATGGAGCCCGGAGCCTTCAGTGGTGCCAGACCA
GGCCTGGGAGGATACAGCCCTCCACCAGAAGAAGCTATGCCCTTTGAGTTTGACCAGCCTGCCCAGAGAGGCTGCAGTCAACTTCTCTTA
CAGGTCCCAGACCTTGCTCCAGGAGGCCCAGGTGCTGCAGGGGTCCCCGGAGCTCCTCCCGAGGAGCCCCAAGCCCTCAGGCCTGCAAAG
GCTGGCTCCAGAGGAGGCTACAGCCCTCCCCCTGAGGAGACTATGCCATTTGAGCTTGATGGAGAAGGATTTGGGGACGACAGCCCACCC
CCGGGGCTTTCCCGAGTTATCGCACAAGTCGACGGCAGCAGCCAGTTCGCGGCAGTCGCGGCCTCGAGTGCGGTCCGCCTCACTCCCGCC
GCGAACGCGCCTCCCCTCTGGGTCCCAGGCGCCATCGGCAGCCCATCCCAAGAGGCTGTCAGACCTCCTTCTAACTTCACGGGCAGCAGC
CCCTGGATGGAGATCTCCGGACCCCCGTTCGAGATTGGCAGCGCCCCCGCTGGGGTCGACGACACTCCCGTCAACATGGACAGCCCCCCA
ATCGCGCTTGACGGCCCGCCCATCAAGGTCTCCGGAGCCCCAGATAAGAGAGAGCGAGCAGAGAGACCCCCAGTTGAGGAGGAAGCAGCA
GAGATGGAAGGAGCCGCTGATGCCGCGGAGGGAGGAAAAGTACCCTCTCCGGGGTACGGATCCCCTGCCGCCGGGGCAGCCTCAGCGGAT
ACCGCTGCCAGGGCAGCCCCTGCAGCCCCAGCCGATCCTGACTCCGGGGCAACCCCAGAAGATCCCGACTCCGGGACAGCACCAGCCGAT
CCTGACTCCGGGGCATTCGCAGCCGATCCCGACTCCGGGGCAGCCCCTGCCGCCCCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCC
CCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCAGCCGATCCAGATGCCGGGGCGGCCCCTGAGGCTCCCGCCGCCCCTGCGGCT
GCTGAGACCCGGGCAGCCCATGTCGCCCCAGCTGCGCCAGACGCAGGGGCTCCCACTGCCCCAGCCGCTTCTGCCACCCGGGCAGCCCAA
GTCCGCCGGGCGGCCTCTGCAGCCCCTGCCTCCGGGGCCAGACGCAAGATCCATCTCAGACCCCCCAGCCCCGAGATCCAGGCTGCCGAT
CCGCCTACTCCGCGGCCTACTCGCGCGTCTGCCTGGCGGGGCAAGTCCGAGAGCAGCCGCGGCCGCCGCGTGTACTACGATGAAGGGGTG
GCCAGCAGCGACGATGACTCCAGCGGAGACGAGTCCGACGATGGGACCTCCGGATGCCTCCGCTGGTTTCAGCATCGGCGAAATCGCCGC
CGCCGAAAGCCCCAGCGCAACTTACTCCGCAACTTTCTCGTGCAAGCCTTCGGGGGCTGCTTCGGTCGATCTGAGAGTCCCCAGCCCAAA
GCCTCGCGCTCTCTCAAGGTCAAGAAGGTACCCCTGGCGGAGAAGCGCAGACAGATGCGCAAAGAAGCCCTGGAGAAGCGGGCCCAGAAG
CGCGCAGAGAAGAAACGCAGTAAGCTCATCGACAAACAACTCCAGGACGAAAAGATGGGCTACATGTGTACGCACCGCCTGCTGCTTCTA
GGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGACAGTGAGAAGGCAACC
AAAGTGCAGGACATCAAAAACAACCTGAAAGAGGCGATTGAAACCATTGTGGCCGCCATGAGCAACCTGGTGCCCCCCGTGGAGCTGGCC
AACCCCGAGAACCAGTTCAGAGTGGACTACATCCTGAGTGTGATGAACGTGCCTGACTTTGACTTCCCTCCCGAATTCTATGAGCATGCC
AAGGCTCTGTGGGAGGATGAAGGAGTGCGTGCCTGCTACGAACGCTCCAACGAGTACCAGCTGATTGACTGTGCCCAGTACTTCCTGGAC
AAGATCGACGTGATCAAGCAGGCTGACTATGTGCCGAGCGATCAGGACCTGCTTCGCTGCCGTGTCCTGACTTCTGGAATCTTTGAGACC
AAGTTCCAGGTGGACAAAGTCAACTTCCACATGTTTGACGTGGGTGGCCAGCGCGATGAACGCCGCAAGTGGATCCAGTGCTTCAACGAT
GTGACTGCCATCATCTTCGTGGTGGCCAGCAGCAGCTACAACATGGTCATCCGGGAGGACAACCAGACCAACCGCCTGCAGGAGGCTCTG
AACCTCTTCAAGAGCATCTGGAACAACAGATGGCTGCGCACCATCTCTGTGATCCTGTTCCTCAACAAGCAAGATCTGCTCGCTGAGAAA
GTCCTTGCTGGGAAATCGAAGATTGAGGACTACTTTCCAGAATTTGCTCGCTACACTACTCCTGAGGATGCTACTCCCGAGCCCGGAGAG
GACCCACGCGTGACCCGGGCCAAGTACTTCATTCGAGATGAGTTTCTGAGGATCAGCACTGCCAGTGGAGATGGGCGTCACTACTGCTAC
CCTCATTTCACCTGCGCTGTGGACACTGAGAACATCCGCCGTGTGTTCAACGACTGCCGTGACATCATTCAGCGCATGCACCTTCGTCAG
TACGAGCTGCTCTAAGAAGGGAACCCCCAAATTTAATTAAAGCCTTAAGCACAATTAATTAAAAGTGAAACGTAATTGTACAAGCAGTTA
ATCACCCACCATAGGGCATGATTAACAAAGCAACCTTTCCCTTCCCCCGAGTGATTTTGCGAAACCCCCTTTTCCCTTCAGCTTGCTTAG
ATGTTCCAAATTTAGAAAGCTTAAGGCGGCCTACAGAAAAAGGAAAAAAGGCCACAAAAGTTCCCTCTCACTTTCAGTAAAAATAAATAA
AACAGCAGCAGCAAACAAATAAAATGAAATAAAAGAAACAAATGAAATAAATATTGTGTTGTGCAGCATTAAAAAAAATCAAAATAAAAA
TTAAATGTGAGCAAAGAAAAAGAAAATGACAACTTCAACATTTCCAAAAAAGACATTGAAATTACTCTCTTCCATGGGGAAAATGGGCAA
TTAAATTGCAGTTTTGAAAATATTACTAGAAATCAAGATCTTACCACCATCCTTTGCAAAATTAAAGGCATCAAGACTGCAAGCACCATT
GCCAACTCTTCTAAGAAAGTTCGGGTCAAGCTGGGAAACCTGGAGCTCTACGTCGAGCAGGAGTCAGTTCCTTCCACATGGTATTTTCTG
ATTGTGCTCCCTGTCTTGCTAGTGATTGTCATTTTTGCGGCCGTGGGGGTGACCAGGCACAAATCGAAGGAGCTGAGTCGCAAACAGAGT
CAACAACTAGAATTGCTGGAAAGCGAGCTCCGGAAAGAGATACGTGACGGCTTTGCTGAGCTGCAGATGGATAAATTGGATGTGGTTGAT
AGTTTTGGAACTGTTCCCTTCCTTGACTACAAACATTTTGCTCTGAGAACTTTCTTCCCTGAGTCAGGTGGCTTCACCCACATCTTCACT
GAAGATATGCATAACAGAGACGCCAACGACAAGAATGAAAGTCTCACAGCTTTGGATGCCCTAATCTGTAATAAAAGCTTTCTTGTTACT
GTCATCCACACCCTTGAAAAGCAGAAGAACTTTTCTGTGAAGGACAGGTGTCTGTTTGCCTCCTTCCTAACCATTGCACTGCAAACCAAG
CTGGTCTACCTGACCAGCATCCTAGAGGTGCTGACCAGGGACTTGATGGAACAGTGTAGTAACATGCAGCCGAAACTCATGCTGAGACGC
ACGGAGTCCGTCGTCGAAAAACTCCTCACAAACTGGATGTCCGTCTGCCTTTCTGGATTTCTCCGGGAGACTGTCGGAGAGCCCTTCTAT
TTGCTGGTGACGACTCTGAACCAGAAAATTAACAAGGGTCCCGTGGATGTAATCACTTGCAAAGCCCTGTACACACTTAATGAAGACTGG
CTGTTGTGGCAGGTTCCGGAATTCAGTACTGTGGCATTAAACGTCGTCTTTGAAAAAATCCCGGAAAACGAGAGTGCAGATGTCTGTCGG
AATATTTCAGTCAATGTTCTCGACTGTGACACCATTGGCCAAGCCAAAGAAAAGATTTTCCAAGCATTCTTAAGCAAAAATGGCTCTCCT
TATGGACTTCAGCTTAATGAAATTGGTCTTGAGCTTCAAATGGGCACACGACAGAAAGAACTTCTGGACATCGACAGTTCCTCCGTGATT
CTTGAAGATGGAATCACCAAGCTAAACACCATTGGCCACTATGAGATATCAAATGGATCCACTATAAAAGTCTTTAAGAAGATAGCAAAT
TTTACTTCAGATGTGGAGTACTCGGATGACCACTGCCATTTGATTTTACCAGATTCGGAAGCATTCCAAGATGTGCAAGGAAAGAGACAT
CGAGGGAAGCACAAGTTCAAAGTAAAAGAAATGTATCTGACAAAGCTGCTGTCGACCAAGGTGGCAATTCATTCTGTGCTTGAAAAACTT
TTTAGAAGCATTTGGAGTTTACCCAACAGCAGAGCTCCATTTGCTATAAAATACTTTTTTGACTTTTTGGACGCCCAGGCTGAAAACAAA
AAAATCACAGATCCTGACGTCGTACATATTTGGAAAACAAACAGCCTTCCTCTTCGCTTCTGGGTAAACATCCTGAAGAACCCTCAGTTT
GTCTTTGACATTAAGAAGACACCACATATAGACGGCTGTTTGTCAGTGATTGCCCAGGCATTCATGGATGCATTTTCTCTCACAGAGCAG
CAACTAGGGAAGGAAGCACCAACTAATAAGCTTCTCTATGCCAAGGATATCCCAACCTACAAAGAAGAAGTAAAATCTTATTACAAAGCA
ATCAGGGATTTGCCTCCATTGTCATCCTCAGAAATGGAAGAATTTTTAACTCAGGAATCTAAGAAACATGAAAATGAATTTAATGAAGAA
GTGGCCTTGACAGAAATTTACAAATACATCGTAAAATATTTTGATGAGATTCTAAATAAACTAGAAAGAGAACGAGGGCTGGAAGAAGCT
CAGAAACAACTCTTGCATGTAAAAGTCTTATTTGATGAAAAGAAGAAATGCAAGTGGATGTAAGCACTCTGGGGCCTGGCTTAATCTGGC
AAAGTTCTTCAGACGACTTGGGAGCAAAATGGCTGCTTGAGCTACTCTGTGTCGTTAATTTGTTGTTTGCACATAGGTTCCACTTTGGGC
ACTGTCTTTTTAAGAGACCAAGGCACATGCACAGCTTTTAGAAAGCATACCAACCCTTGTGCCTGTGTGTATACCGTGGGAACCCTTCTG
TAAATAGAGTTGAAGTGGTTGTTGCAAACAGCCTCCTTGTTTACAGAGAATACAAGGCCAGTAAGCGAATGTCAGTATTGTAACTACAGT
CTCCACTTAAGCACAATGATATAAGTGGTTTTGTTTGAAAACTACAGCTATGTAGCACTTGTGCTACACTGCACCTCTGCATTGTAAAGG
GATACTGCCAGTGCTCAAAACAAAATGTGAAATGAGTCATTTGGAAACAAGGTGGGGGTGTTAGGGCAACCTCGAGGATTTGCAGCATTG
AAACTTTCCCCAGTAGTTCTTGGAAAAGCTGACCGCAGAATTTGGTAGTGTACACTTAGCATTTGTGAGTGTGTGTGTGTGTTTAAACCA
AAAACTAACAGTGTTGCAACATTGTTGAAAGGGCTCGTGTTTTTCAGTGGTCATCAACTGCACTCCATCAAACTCACCTCCATTTCACCA
AGGAGCTCTAAAGTAAGGAGAGTGGGCTTTATTTAAATGAACAGCATTTTAACCAGATACTTTGTCCTAATGTATGTTCCTTTTCTTCAT
CTGTTTTTTCATACTAAATGTATTTGATAGTGGACATGTTGGATATTATACAAAAAAATCATTAATTCATTTCTGTTCCAAAACCTTTGA
TCAGAACGATCTGTGGAAGAGTAACTCCATTTCTATATGAGTGAGTGTCTCCTTGCTTTAGATTTCTGGTGAACCCTGTGGTTATGAATA
CTTGTGTGTGATTTAAAAAAAAAAAGATACATTTTACATTTTATCGAATTGCTGTTCACACTGGAGTATTATATATAAATATATATATTT
GAGGCCCAAGGCCTGAAAAATATTAGTATACAACTTGGTATCTTAGTCTTACTATGTACTTTTTGAAAGTATTCCTCGCAGGAGAAAGAA
TTTAAAATACCCATTTTATTCATGCCTTTCTTTTTAAAGAATTCTCTATCCAGTTATACTGTAGTCTTTTTAGTGCTGATTTTTTAATTC
CTGAATTTTTGCTGCTCATGACCAGTTTTAATACCACTGTGTTTTCCTTCTATTAAACCAGAAGAAGTAAACAGCATAATTGGCAACTCT
TGAGCTTTTCTTGTGGCAGGCACCTTTTACCCTTGGTGCTCCAAATCCCCCATCTAGGAAAGAAAATTTTTTCAAGTCAAATAACATTGA
TCACATATTCCTTGAAATCATTTACCAACACTGTATGGAGCATTAGGATTTAAATATGAATTTGTCTTAAAGGCAATTCCTTTTTGCTTC
TGTATTATCTGGAAAAGCATGAGAGAGGTGACACCTCAACAAACTGATCAGAGAAAATAAGCAGTTACTACCCTGATAGGCACCTTCCCA
ATCCTGTTGCTTTTGACCATTGTCTGTCCAACGGACACACCTCAAACAAACAAAACTACCAAATAGATGACAGATCAGAATAAAGGTGAG
AGGTCTGGTCCCCATTGAAGGCTGCTACAGTCTTCAAAGAGGTGAAGGAGTTCATAAGAGAACAACAGTAGGAAAGTTGAGAGCCAAGGG
TAGGAGAGTTGCCCAAAAGACTTCCCCTACTACTTTAGGGTACTGAAAACTCAAAGGATCAGCTACAGCTTTATCTAAGTATTTACTAAA
TGCTACATGAGGGTGTCCCTGTCCAGCTTTCTGGCACATGAGTCCTGTGTGGAGAGTTACCTCCTCTTCCAGGGACTGTGCTGTTGGGAA
CTTTGGGCAAGTCACTTACCTCTTTGTGCCTCAATTTCTGTATAATATTTCTAAGCTACCTCACTGAGGTGGTATGAAGATTCACTAATG
TATGTAGCGTGTTTGTCAATCCTCCAGTGAAAAGCACTATCTAGATCACATTTTGGATCACATTAGCCAAATGCAGTAAATGGCCAAATT
AGATGTGTGCTGAAGACAATCAGTCACTGGGTCTATATTAAACAGCAACCAGAGCAACAAATGGCAAACAATTTCTATTTTCAAGTTTCT
TTGCATATTTTTTTGGTGCAAAACCATTTATAAACTTTTTTTTCTAACACTAGTGTCTACAGCAGCATTCAAAAAAATTCTGTTACCTTT
TCTGTATTAGGATTTAAAGTCTATTTCTTATTGTATACCTGATTGAAGCTGTTCTTGGAGATGAATGTTTTAAATGTCTATATCCAAAAA

>33639_33639_7_GNAS-PLXNC1_GNAS_chr20_57486241_ENST00000371102_PLXNC1_chr12_94642003_ENST00000258526_length(amino acids)=1023AA_BP=
MGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAGA
HGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQ
VPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAVRLTPAA
NAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAE
MEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAP
ADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADP
PTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRSESPQPKA
SRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKATK
VQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDK
IDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALN
LFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYP

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Fusion Gene PPI Analysis for GNAS-PLXNC1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GNAS-PLXNC1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GNAS-PLXNC1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource