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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GNE-ROCK1 (FusionGDB2 ID:33729)

Fusion Gene Summary for GNE-ROCK1

check button Fusion gene summary
Fusion gene informationFusion gene name: GNE-ROCK1
Fusion gene ID: 33729
HgeneTgene
Gene symbol

GNE

ROCK1

Gene ID

10020

6093

Gene nameglucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinaseRho associated coiled-coil containing protein kinase 1
SynonymsDMRV|GLCNE|IBM2|NM|Uae1P160ROCK|ROCK-I
Cytomap

9p13.3

18q11.1

Type of geneprotein-codingprotein-coding
Descriptionbifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinaseN-acylmannosamine kinaseUDP-GlcNAc-2-epimerase/ManAc kinaseUDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinaserho-associated protein kinase 1p160 ROCK-1renal carcinoma antigen NY-REN-35
Modification date2020032820200322
UniProtAcc

Q9Y223

.
Ensembl transtripts involved in fusion geneENST00000396594, ENST00000539815, 
ENST00000543356, ENST00000377902, 
ENST00000447283, ENST00000539208, 
ENST00000399799, 
Fusion gene scores* DoF score7 X 9 X 6=3784 X 4 X 3=48
# samples 105
** MAII scorelog2(10/378*10)=-1.91838623444635
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/48*10)=0.0588936890535686
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: GNE [Title/Abstract] AND ROCK1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGNE(36236829)-ROCK1(18650574), # samples:3
Anticipated loss of major functional domain due to fusion event.GNE-ROCK1 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
GNE-ROCK1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
GNE-ROCK1 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneROCK1

GO:0006468

protein phosphorylation

23093407

TgeneROCK1

GO:0007159

leukocyte cell-cell adhesion

12082081

TgeneROCK1

GO:0018105

peptidyl-serine phosphorylation

18573880

TgeneROCK1

GO:0022614

membrane to membrane docking

12082081

TgeneROCK1

GO:0030334

regulation of cell migration

23093407

TgeneROCK1

GO:0032091

negative regulation of protein binding

18573880

TgeneROCK1

GO:0032956

regulation of actin cytoskeleton organization

25911094

TgeneROCK1

GO:0050900

leukocyte migration

12082081

TgeneROCK1

GO:0050901

leukocyte tethering or rolling

12082081

TgeneROCK1

GO:0070507

regulation of microtubule cytoskeleton organization

23093407


check buttonFusion gene breakpoints across GNE (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ROCK1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-56-A49D-01AGNEchr9

36236829

-ROCK1chr18

18650574

-
ChimerDB4LUSCTCGA-56-A49DGNEchr9

36236828

-ROCK1chr18

18650574

-
ChimerDB4LUSCTCGA-56-A49DGNEchr9

36236829

-ROCK1chr18

18650574

-


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Fusion Gene ORF analysis for GNE-ROCK1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000396594ENST00000399799GNEchr9

36236829

-ROCK1chr18

18650574

-
Frame-shiftENST00000396594ENST00000399799GNEchr9

36236828

-ROCK1chr18

18650574

-
Frame-shiftENST00000539815ENST00000399799GNEchr9

36236829

-ROCK1chr18

18650574

-
Frame-shiftENST00000539815ENST00000399799GNEchr9

36236828

-ROCK1chr18

18650574

-
Frame-shiftENST00000543356ENST00000399799GNEchr9

36236829

-ROCK1chr18

18650574

-
Frame-shiftENST00000543356ENST00000399799GNEchr9

36236828

-ROCK1chr18

18650574

-
In-frameENST00000377902ENST00000399799GNEchr9

36236829

-ROCK1chr18

18650574

-
In-frameENST00000377902ENST00000399799GNEchr9

36236828

-ROCK1chr18

18650574

-
In-frameENST00000447283ENST00000399799GNEchr9

36236829

-ROCK1chr18

18650574

-
In-frameENST00000447283ENST00000399799GNEchr9

36236828

-ROCK1chr18

18650574

-
intron-3CDSENST00000539208ENST00000399799GNEchr9

36236829

-ROCK1chr18

18650574

-
intron-3CDSENST00000539208ENST00000399799GNEchr9

36236828

-ROCK1chr18

18650574

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000447283GNEchr936236829-ENST00000399799ROCK1chr1818650574-927082081147911326
ENST00000377902GNEchr936236829-ENST00000399799ROCK1chr1818650574-944099098149611326
ENST00000447283GNEchr936236828-ENST00000399799ROCK1chr1818650574-927082081147911326
ENST00000377902GNEchr936236828-ENST00000399799ROCK1chr1818650574-944099098149611326

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000447283ENST00000399799GNEchr936236829-ROCK1chr1818650574-0.0001294960.99987054
ENST00000377902ENST00000399799GNEchr936236829-ROCK1chr1818650574-0.0001442210.99985576
ENST00000447283ENST00000399799GNEchr936236828-ROCK1chr1818650574-0.0001294960.99987054
ENST00000377902ENST00000399799GNEchr936236828-ROCK1chr1818650574-0.0001442210.99985576

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Fusion Genomic Features for GNE-ROCK1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GNE-ROCK1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:36236829/chr18:18650574)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GNE

Q9Y223

.
FUNCTION: Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development (By similarity). Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. {ECO:0000250, ECO:0000269|PubMed:10334995}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneROCK1chr9:36236828chr18:18650574ENST000003997990331011_1102311355.0Coiled coilOntology_term=ECO:0000255
TgeneROCK1chr9:36236828chr18:18650574ENST00000399799033422_692311355.0Coiled coilOntology_term=ECO:0000255
TgeneROCK1chr9:36236829chr18:18650574ENST000003997990331011_1102311355.0Coiled coilOntology_term=ECO:0000255
TgeneROCK1chr9:36236829chr18:18650574ENST00000399799033422_692311355.0Coiled coilOntology_term=ECO:0000255
TgeneROCK1chr9:36236828chr18:18650574ENST00000399799033636_980311355.0Compositional biasNote=Glu-rich
TgeneROCK1chr9:36236829chr18:18650574ENST00000399799033636_980311355.0Compositional biasNote=Glu-rich
TgeneROCK1chr9:36236828chr18:18650574ENST000003997990331118_1317311355.0DomainPH
TgeneROCK1chr9:36236828chr18:18650574ENST00000399799033341_409311355.0DomainAGC-kinase C-terminal
TgeneROCK1chr9:36236828chr18:18650574ENST00000399799033479_556311355.0DomainREM-1
TgeneROCK1chr9:36236828chr18:18650574ENST0000039979903376_338311355.0DomainProtein kinase
TgeneROCK1chr9:36236828chr18:18650574ENST00000399799033949_1015311355.0DomainRhoBD
TgeneROCK1chr9:36236829chr18:18650574ENST000003997990331118_1317311355.0DomainPH
TgeneROCK1chr9:36236829chr18:18650574ENST00000399799033341_409311355.0DomainAGC-kinase C-terminal
TgeneROCK1chr9:36236829chr18:18650574ENST00000399799033479_556311355.0DomainREM-1
TgeneROCK1chr9:36236829chr18:18650574ENST0000039979903376_338311355.0DomainProtein kinase
TgeneROCK1chr9:36236829chr18:18650574ENST00000399799033949_1015311355.0DomainRhoBD
TgeneROCK1chr9:36236828chr18:18650574ENST0000039979903382_90311355.0Nucleotide bindingATP
TgeneROCK1chr9:36236829chr18:18650574ENST0000039979903382_90311355.0Nucleotide bindingATP
TgeneROCK1chr9:36236828chr18:18650574ENST000003997990331115_1354311355.0RegionNote=Auto-inhibitory
TgeneROCK1chr9:36236828chr18:18650574ENST00000399799033707_946311355.0RegionSHROOM3 binding
TgeneROCK1chr9:36236828chr18:18650574ENST00000399799033998_1010311355.0RegionNote=RHOA binding
TgeneROCK1chr9:36236829chr18:18650574ENST000003997990331115_1354311355.0RegionNote=Auto-inhibitory
TgeneROCK1chr9:36236829chr18:18650574ENST00000399799033707_946311355.0RegionSHROOM3 binding
TgeneROCK1chr9:36236829chr18:18650574ENST00000399799033998_1010311355.0RegionNote=RHOA binding
TgeneROCK1chr9:36236828chr18:18650574ENST000003997990331228_1281311355.0Zinc fingerPhorbol-ester/DAG-type
TgeneROCK1chr9:36236829chr18:18650574ENST000003997990331228_1281311355.0Zinc fingerPhorbol-ester/DAG-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGNEchr9:36236828chr18:18650574ENST00000377902-412411_420256723.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236828chr18:18650574ENST00000377902-412543_552256723.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236828chr18:18650574ENST00000396594-412411_420287754.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236828chr18:18650574ENST00000396594-412543_552287754.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236828chr18:18650574ENST00000447283-411411_420256649.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236828chr18:18650574ENST00000447283-411543_552256649.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236828chr18:18650574ENST00000539208-110411_4200613.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236828chr18:18650574ENST00000539208-110543_5520613.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236828chr18:18650574ENST00000539815-312411_4202561065.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236828chr18:18650574ENST00000539815-312543_5522561065.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236829chr18:18650574ENST00000377902-412411_420256723.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236829chr18:18650574ENST00000377902-412543_552256723.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236829chr18:18650574ENST00000396594-412411_420287754.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236829chr18:18650574ENST00000396594-412543_552287754.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236829chr18:18650574ENST00000447283-411411_420256649.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236829chr18:18650574ENST00000447283-411543_552256649.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236829chr18:18650574ENST00000539208-110411_4200613.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236829chr18:18650574ENST00000539208-110543_5520613.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236829chr18:18650574ENST00000539815-312411_4202561065.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236829chr18:18650574ENST00000539815-312543_5522561065.0Nucleotide bindingNote=ATP
HgeneGNEchr9:36236828chr18:18650574ENST00000377902-412406_722256723.0RegionNote=N-acetylmannosamine kinase
HgeneGNEchr9:36236828chr18:18650574ENST00000396594-412406_722287754.0RegionNote=N-acetylmannosamine kinase
HgeneGNEchr9:36236828chr18:18650574ENST00000447283-411406_722256649.0RegionNote=N-acetylmannosamine kinase
HgeneGNEchr9:36236828chr18:18650574ENST00000539208-110406_7220613.0RegionNote=N-acetylmannosamine kinase
HgeneGNEchr9:36236828chr18:18650574ENST00000539815-312406_7222561065.0RegionNote=N-acetylmannosamine kinase
HgeneGNEchr9:36236829chr18:18650574ENST00000377902-412406_722256723.0RegionNote=N-acetylmannosamine kinase
HgeneGNEchr9:36236829chr18:18650574ENST00000396594-412406_722287754.0RegionNote=N-acetylmannosamine kinase
HgeneGNEchr9:36236829chr18:18650574ENST00000447283-411406_722256649.0RegionNote=N-acetylmannosamine kinase
HgeneGNEchr9:36236829chr18:18650574ENST00000539208-110406_7220613.0RegionNote=N-acetylmannosamine kinase
HgeneGNEchr9:36236829chr18:18650574ENST00000539815-312406_7222561065.0RegionNote=N-acetylmannosamine kinase


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Fusion Gene Sequence for GNE-ROCK1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>33729_33729_1_GNE-ROCK1_GNE_chr9_36236828_ENST00000377902_ROCK1_chr18_18650574_ENST00000399799_length(transcript)=9440nt_BP=990nt
GTGGGCGTGGCTGGGCGAGCGAGGAGTGGGGACAAGGTCGAGCGACGAGTCGTCTACCCGCGCGCCCGAGCGCGGAAACCGAGGGGCAGG
CTCGCGCTCTGCCTGCTTCGTGGCGCTTGGTTCGTCCCTCGCCCGAGGAGCGCGGTGGCGGCGTGGGAGGGAGCCTCTGACGGCGTCTGG
AACTCTATTTTAAGAACCTCTCAAAACGAAACAAGCAAATCATGGAGAAGAATGGAAATAACCGAAAGCTGCGGGTTTGTGTTGCTACTT
GTAACCGTGCAGATTATTCTAAACTTGCCCCGATCATGTTTGGCATTAAAACCGAACCTGAGTTCTTTGAACTTGATGTTGTGGTACTTG
GCTCTCACCTGATAGATGACTATGGAAATACATATCGAATGATTGAACAAGATGACTTTGACATTAACACCAGGCTACACACAATTGTGA
GGGGAGAAGATGAGGCAGCCATGGTGGAGTCAGTAGGCCTGGCCCTAGTGAAGCTGCCAGATGTCCTTAATCGCCTGAAGCCTGATATCA
TGATTGTTCATGGAGACAGGTTTGATGCCCTGGCTCTGGCCACATCTGCTGCCTTGATGAACATCCGAATCCTTCACATTGAAGGTGGGG
AAGTCAGTGGGACCATTGATGACTCTATCAGACATGCCATAACAAAACTGGCTCATTATCATGTGTGCTGCACCCGCAGTGCAGAGCAGC
ACCTGATATCCATGTGTGAGGACCATGATCGCATCCTTTTGGCAGGCTGCCCTTCCTATGACAAACTTCTCTCAGCCAAGAACAAAGACT
ACATGAGCATCATTCGCATGTGGCTAGGTGATGATGTAAAATCTAAAGATTACATTGTTGCACTACAGCACCCTGTGACCACTGACATTA
AGCATTCCATAAAAATGTTTGAATTAACATTGGATGCACTTATCTCATTTAACAAGCGGACCCTAGTCCTGTTTCCAAATATTGACGCAG
GATGGATTGGATGCTTTGGTATATGATTTGGATTTTCCTGCCTTAAGAAAAAACAAAAATATTGACAACTTTTTAAGCAGATATAAAGAC
ACAATAAATAAAATCAGAGATTTACGAATGAAAGCTGAAGATTATGAAGTAGTGAAGGTGATTGGTAGAGGTGCATTTGGAGAAGTTCAA
TTGGTAAGGCATAAATCCACCAGGAAGGTATATGCTATGAAGCTTCTCAGCAAATTTGAAATGATAAAGAGATCTGATTCTGCTTTTTTC
TGGGAAGAAAGGGACATCATGGCTTTTGCCAACAGTCCTTGGGTTGTTCAGCTTTTTTATGCATTCCAAGATGATCGTTATCTCTACATG
GTGATGGAATACATGCCTGGTGGAGATCTTGTAAACTTAATGAGCAACTATGATGTGCCTGAAAAATGGGCACGATTCTATACTGCAGAA
GTAGTTCTTGCATTGGATGCAATCCATTCCATGGGTTTTATTCACAGAGATGTGAAGCCTGATAACATGCTGCTGGATAAATCTGGACAT
TTGAAGTTAGCAGATTTTGGTACTTGTATGAAGATGAATAAGGAAGGCATGGTACGATGTGATACAGCGGTTGGAACACCTGATTATATT
TCCCCTGAAGTATTAAAATCCCAAGGTGGTGATGGTTATTATGGAAGAGAATGTGACTGGTGGTCGGTTGGGGTATTTTTATACGAAATG
CTTGTAGGTGATACACCTTTTTATGCAGATTCTTTGGTTGGAACTTACAGTAAAATTATGAACCATAAAAATTCACTTACCTTTCCTGAT
GATAATGACATATCAAAAGAAGCAAAAAACCTTATTTGTGCCTTCCTTACTGACAGGGAAGTGAGGTTAGGGCGAAATGGTGTAGAAGAA
ATCAAACGACATCTCTTCTTCAAAAATGACCAGTGGGCTTGGGAAACGCTCCGAGACACTGTAGCACCAGTTGTACCCGATTTAAGTAGT
GACATTGATACTAGTAATTTTGATGACTTGGAAGAAGATAAAGGAGAGGAAGAAACATTCCCTATTCCTAAAGCTTTCGTTGGCAATCAA
CTACCTTTTGTAGGATTTACATATTATAGCAATCGTAGATACTTATCTTCAGCAAATCCTAATGATAACAGAACTAGCTCCAATGCAGAT
AAAAGCTTGCAGGAAAGTTTGCAAAAAACAATCTATAAGCTGGAAGAACAGCTGCATAATGAAATGCAGTTAAAAGATGAAATGGAGCAG
AAGTGCAGAACCTCAAACATAAAACTAGACAAGATAATGAAAGAATTGGATGAAGAGGGAAATCAAAGAAGAAATCTAGAATCTACAGTG
TCTCAGATTGAGAAGGAGAAAATGTTGCTACAGCATAGAATTAATGAGTACCAAAGAAAAGCTGAACAGGAAAATGAGAAGAGAAGAAAT
GTAGAAAATGAAGTTTCTACATTAAAGGATCAGTTGGAAGACTTAAAGAAAGTCAGTCAGAATTCACAGCTTGCTAATGAGAAGCTGTCC
CAGTTACAAAAGCAGCTAGAAGAAGCCAATGACTTACTTAGGACAGAATCGGACACAGCTGTAAGATTGAGGAAGAGTCACACAGAGATG
AGCAAGTCAATTAGTCAGTTAGAGTCCCTGAACAGAGAGTTGCAAGAGAGAAATCGAATTTTAGAGAATTCTAAGTCACAAACAGACAAA
GATTATTACCAGCTGCAAGCTATATTAGAAGCTGAACGAAGAGACAGAGGTCATGATTCTGAGATGATTGGAGACCTTCAAGCTCGAATT
ACATCTTTACAAGAGGAGGTGAAGCATCTCAAACATAATCTCGAAAAAGTGGAAGGAGAAAGAAAAGAGGCTCAAGACATGCTTAATCAC
TCAGAAAAGGAAAAGAATAATTTAGAGATAGATTTAAACTACAAACTTAAATCATTACAACAACGGTTAGAACAAGAGGTAAATGAACAC
AAAGTAACCAAAGCTCGTTTAACTGACAAACATCAATCTATTGAAGAGGCAAAGTCTGTGGCAATGTGTGAGATGGAAAAAAAGCTGAAA
GAAGAAAGAGAAGCTCGAGAGAAGGCTGAAAATCGGGTTGTTCAGATTGAGAAACAGTGTTCCATGCTAGACGTTGATCTGAAGCAATCT
CAGCAGAAACTAGAACATTTGACTGGAAATAAAGAAAGGATGGAGGATGAAGTTAAGAATCTAACCCTGCAACTGGAGCAGGAATCAAAT
AAGCGGCTGTTGTTACAAAATGAATTGAAGACTCAAGCATTTGAGGCAGACAATTTAAAAGGTTTAGAAAAGCAGATGAAACAGGAAATA
AATACTTTATTGGAAGCAAAGAGATTATTAGAATTTGAGTTAGCTCAGCTTACGAAACAGTATAGAGGAAATGAAGGACAGATGCGGGAG
CTACAAGATCAGCTTGAAGCTGAGCAATATTTCTCGACACTTTATAAAACCCAGGTAAAGGAACTTAAAGAAGAAATTGAAGAAAAAAAC
AGAGAAAATTTAAAGAAAATACAGGAACTACAAAATGAAAAAGAAACTCTTGCTACTCAGTTGGATCTAGCAGAAACAAAAGCTGAGTCT
GAGCAGTTGGCGCGAGGCCTTCTGGAAGAACAGTATTTTGAATTGACGCAAGAAAGCAAGAAAGCTGCTTCAAGAAATAGACAAGAGATT
ACAGATAAAGATCACACTGTTAGTCGGCTTGAAGAAGCAAACAGCATGCTAACCAAAGATATTGAAATATTAAGAAGAGAGAATGAAGAG
CTAACAGAGAAAATGAAGAAGGCAGAGGAAGAATATAAACTGGAGAAGGAGGAGGAGATCAGTAATCTTAAGGCTGCCTTTGAAAAGAAT
ATCAACACTGAACGAACCCTTAAAACACAGGCTGTTAACAAATTGGCAGAAATAATGAATCGAAAAGATTTTAAAATTGATAGAAAGAAA
GCTAATACACAAGATTTGAGAAAGAAAGAAAAGGAAAATCGAAAGCTGCAACTGGAACTCAACCAAGAAAGAGAGAAATTCAACCAGATG
GTAGTGAAACATCAGAAGGAACTGAATGACATGCAAGCGCAATTGGTAGAAGAATGTGCACATAGGAATGAGCTTCAGATGCAGTTGGCC
AGCAAAGAGAGTGATATTGAGCAATTGCGTGCTAAACTTTTGGACCTCTCGGATTCTACAAGTGTTGCTAGTTTTCCTAGTGCTGATGAA
ACTGATGGTAACCTCCCAGAGTCAAGAATTGAAGGTTGGCTTTCAGTACCAAATAGAGGAAATATCAAACGATATGGCTGGAAGAAACAG
TATGTTGTGGTAAGCAGCAAAAAAATTTTGTTCTATAATGACGAACAAGATAAGGAGCAATCCAATCCATCTATGGTATTGGACATAGAT
AAACTGTTTCACGTTAGACCTGTAACCCAAGGAGATGTGTATAGAGCTGAAACTGAAGAAATTCCTAAAATATTCCAGATACTATATGCA
AATGAAGGTGAATGTAGAAAAGATGTAGAGATGGAACCAGTACAACAAGCTGAAAAAACTAATTTCCAAAATCACAAAGGCCATGAGTTT
ATTCCTACACTCTACCACTTTCCTGCCAATTGTGATGCCTGTGCCAAACCTCTCTGGCATGTTTTTAAGCCACCCCCTGCCCTAGAGTGT
CGAAGATGCCATGTTAAGTGCCACAGAGATCACTTAGATAAGAAAGAGGACTTAATTTGTCCATGTAAAGTAAGTTATGATGTAACATCA
GCAAGAGATATGCTGCTGTTAGCATGTTCTCAGGATGAACAAAAAAAATGGGTAACTCATTTAGTAAAGAAAATCCCTAAGAATCCACCA
TCTGGTTTTGTTCGTGCTTCCCCTCGAACGCTTTCTACAAGATCCACTGCAAATCAGTCTTTCCGGAAAGTGGTCAAAAATACATCTGGA
AAAACTAGTTAACCATGTGACTGAGTGCCCTGTGGAATCGTGTGGGATGCTACCTGATAAACCAGGCTTCTTTAACCATGCAGAGCAGAC
AGGCTGTTTCTTTGACACAAATATCACAGGCTTCAGGGTTAAGATTGCTGTTTTTCTGTCCTTGCTTTGGCACAACACACTGAGGGTTTT
TTTTATTGCGGGTTTGCCTACAGGTAGATTAGATTAATTATTACTATGTAATGCAAGTACAGTTGGGGGAAAGCTTAGGTAGATATATTT
TTTTTAAAAGGTGCTGCCTTTTTGGATTTATAAGAAAATGCCTGTCAGTCGTGATAGAACAGAGTTTTCCTCATATGAGTAAGAGGAAGG
GACTTTCACTTTCAAGTGGAACAGCCATCACTATCAAGATCAGCTCATGGAAGGAGTAAAGAAAATATCTCAAAATGAGACAAACTGAAG
TTTTGTTTTTTTTTTAATGACTTAAGTTTTTGTGCTCTTGCAAGACTATACAAAACTATTTTAAGAAAGCAGTGATATCACTTGAACTTC
AGTGCCCTCACTGTAGAATTTAAAAGCCTTACTGTTGATTGCCCATGTTGGACTTGATGGAGAAATTAAATATCTTTCATTATGCTTTAC
AAAATACTGTATATGTTTCAGCAAGTTTGGGGAATGGGAGAGGACAAAAAAAAGTTACATTTAATCTATGCATTTTTGCCAAGCCATATT
GAGTTATTTTACTACTAGAGACATTAGGAAACTAACTGTACAAAAGAACCAAGTTTAAAAGCATTTTGTGGGGTACATCATTTCTATAAT
TGTATAATGTATTTCTTTGTGGTTTTAAATGATAAAGACATTAAGTTAACAAACATATAAGAAATGTATGCACTGTTTGAAATGTAAATT
ATTCTTAGAACACTTTCAATGGGGGTTGCATTGTCCTTTTAGTGCCTTAATTTGAGATAATTATTTTACTGCCATGAGTAAGTATAGAAA
TTTCAAAAAATGTATTTTCAAAAAATTATGTGTGTCAGTGAGTTTTTCATTGATAATTGGTTTAATTTAAAATATTTAGAGGTTTGTTGG
ACTTTCATAAATTGAGTACAATCTTTGCATCAAACTACCTGCTACAATAATGACTTTATAAAACTGCAAAAAATGTAGAAGGTTGCACCA
ACATAAAAAGGAAATATGGCAATACATCCATGATGTTTTCCAGTTAACATAGGAATTACCAGATAAATACTGTTAAACTCTTGTCCAGTA
ACAAGAGTTGATTCATATGGACAGTATGATTTATTGTTTATTTTTTTAACCAAATACCTCCTCAGTAATTTATAATGGCTTTGCAGTAAT
GTGTATCAGATAAGAAGCACTGGAAAACCGATCGTCTCTAGGATGATATGCATGTTTCAAGTGGTATTGAAAGCCGCACTGATGGATATG
TAATAATAAACATATCTGTTATTAATATACTAATGACTCTGTGCTCATTTAATGAGAAATAAAAGTAATTTATGGATGGGTATCTTTAAT
TTTTACTGCAATGTGTTTTCTCATGGCTGAAATGAATGGAAAACATACTTCAAATTAGTCTCTGATTGTATATAAATGTTTGTGAAATTC
CATGGTTAGATTAAAGTGTATTTTTAAAAGATAAAACGTGGTCTTGGGCTCTAAAACAAGAGTGGGAATAGTTCACATGAAAAGCTGGCT
AAAGTGTGTTGGAAAACAATTCTCCATGGGTCTCTTGCATTTCTACACATCAGGGAAGCAGAGGCTCTGACAACCTTTCTTTTGACTATC
TTTTCCAAGGATATTTATGTAGTAAACAGCCTTGGAAGATAGAGTTCTCCCTTGTGAGGATGTCGGGTTCTTTTACTGTCCAGTATAATA
AAGATAACGTCTCCCACCTATGATGCAAACCCACTGTGTGCTCAGCACCCACCTGGGCCACTCTGCATTGCCCACATGGGGCTTGGAGGG
CAAAGGGAACTGATGGAACGTGAAACTTATGCTGCTTTTGCTGTGCTGTGAATGAAGTCATCTGACTCTGACCCAGGGGTCTCATCTCTT
TTGTCAGGATCCATGAAACTGTGACTGGCAGCATGCAAACAGGATAAAATCTCAGCACAGTTCCTGACGGTGTCCTTACTACCTTCTCAG
ACTCATCACCATTACCTAATATTTTAAGGTCCAGTTGCAGAGAACAGAGTTAATTCTAATTAGTTTAAGCAAGAGAAGACTTTCCAAATG
ACATACTAATCTGAACTTAGAATTGTTGAGAACTGAGAGAGCTTTGAGGAATCACTCCCAATGCCACATTACAGAACTGGGTCAACCAGG
AGAGCTGCTTCCTCTTCTAAGTTCAGGAAACCACTCACTCCCAAGTATACCAATATTGAGAGGGTCCAGATAGTGCCATAATCAGGAATC
CACACTACCACTGCTGGTTCTCTGCAACACTTGTCAGGCTTGCTACAATCTACCTCCAGTTAGATGTTTTGTACCATTCCTCTTGCCACT
TAAGAACCTCATGTCTGCACACTGCCTCAGAAAAGGCACTTCCATGACCCTGCTTGCTGGCATTTAGCACAGCCTGCATCTCACGTCTGC
CTTCTCTAGGTGCATCTACGTGGCCAAAATTAAATCACATCCAGACCCCTAGCTGCAAGAAAGTCTGAGAAATATAGCCTCTAGCTTTCT
CTCTAATTTGTTACAGGAGGACACACTAGGAGTGTGGAATGAAGGTTCAGCATTGAGTTAGCCCATGCACCCACACCTGTAAGCTTCTCT
GAGATCAGGAACTCCAGCTTTGGGCAACAAAGAAAACATAGCCACTGTCATTATTCACAGGTTCACTCATGACCTGTCATTTGGGGTTTC
AGCTTAAATTAACCCATTCACCCTTCATTTAAAGTAAAAAAAATAAGTAAAAGAACTTAAATGACAAACTCATAGTTACTTGAGTTTGTA
ATTCATAGTTAACTTTCACAGTTCTATAATCAATCTGGAATTCAGAGTGAGGTAGAGATCAAGCAGTATTTCTCCCATATGGATATTCAG
TTGATACTGCAGTATTCATTGAAAATACTTCTTTCCTGCATCGTAATTCAGGTGAACAATCCATTGGTGTTATTTCTGTGTCCTTGCCAA
TATCACACTTTTAATTACTGTAACTTTATAATAAGATTTTATATCTGTAGTAGAAGTCCAACTTTGTAATCCCTCCCAATTGGCTTGGCT
ATTCTTGGCCTTTTGCATTTCCATATAATTTTTTATTTTTGTTTTGAAACGAAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCAGTGGCG
CGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATCCTCCTGCCTCAGACTCCCGAGTAGCTGGGATTACAGGTGCCCACC
ACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGCCTGGTCTTGAACTCCTGACCTCAGGTGATC
CACACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCTGGTTGCATTCCCATATAAATTTAAAAACAATCTA
CTGAAAGATGTATACGACCTCCACCAAGAAAATTGTAAGACATTTGGAGAAGTTTAAAAAGACATGAATAAACGGAAATGGTTTTTTTAA
ATAAACAAATGATTTTTAAAGTTGATCATTAGGTTAATAAATAGTCATATAATGACAATCCGATGAGATTATGTTGCCCAGGGTGGTCTC
TAACTCCTAGCCTCAAGCAGTTTTACTCTCTCATTACAGGTGTAGGCCACCGTGCCTGGCCTGACACTTGGAAATCTTAATCACAATTAT
TCTTTGTTTTTATAATGTTTACTGTTCAAATCAATTTCTGGTTGGATAGTATGTATATATAAAGCCATGCTCAATGGCCTAGATATATTT
ACTGCCAAATCTTTTATGCTTTTAGTGTTTTTTTTCTGGACAAGATCTATGCTTATTGCAATAAATTAAATGCAAAGAATATTCTAGTAG
AAAGTCAGTCTGCACTTCCTAAACCCCACCCCACCCCACCAATTCCTTCATAACTGTTATTAACAGTTAGCTGTGTTTTCTAATGGATTA
TCTCCAAAGTATATGTAACTCAGATTTTTGTGAGGTAGGAAAAGAATAACATTAATTCCACTTCACATATTGAAAGTCTAACATACAAAG
AGATTAAATATCTCCTTTCTTTTGCCAAATGTTAATGAATTGTCTTATGAGAATTAAGATATGATACTTTCTCCCAAGCTATACTGTTTC
CCATAAAGTATTTGAGATGTTGGAGATTCAAGGGAAAAAATATAAATGCTTAGAAATAAAGTGTATAATGCAAAGATTGTGAATAAAGTG

>33729_33729_1_GNE-ROCK1_GNE_chr9_36236828_ENST00000377902_ROCK1_chr18_18650574_ENST00000399799_length(amino acids)=1326AA_BP=3
MTQDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDS
AFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDK
SGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLT
FPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIPKAFV
GNQLPFVGFTYYSNRRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLE
STVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSH
TEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDM
LNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDL
KQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQ
MRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNR
QEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKID
RKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKLLDLSDSTSVASFPS
ADETDGNLPESRIEGWLSVPNRGNIKRYGWKKQYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQI
LYANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCDACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLICPCKVSYD

--------------------------------------------------------------
>33729_33729_2_GNE-ROCK1_GNE_chr9_36236828_ENST00000447283_ROCK1_chr18_18650574_ENST00000399799_length(transcript)=9270nt_BP=820nt
CGGCGTCTGGAACTCTATTTTAAGAACCTCTCAAAACGAAACAAGCAAATCATGGAGAAGAATGGAAATAACCGAAAGCTGCGGGTTTGT
GTTGCTACTTGTAACCGTGCAGATTATTCTAAACTTGCCCCGATCATGTTTGGCATTAAAACCGAACCTGAGTTCTTTGAACTTGATGTT
GTGGTACTTGGCTCTCACCTGATAGATGACTATGGAAATACATATCGAATGATTGAACAAGATGACTTTGACATTAACACCAGGCTACAC
ACAATTGTGAGGGGAGAAGATGAGGCAGCCATGGTGGAGTCAGTAGGCCTGGCCCTAGTGAAGCTGCCAGATGTCCTTAATCGCCTGAAG
CCTGATATCATGATTGTTCATGGAGACAGGTTTGATGCCCTGGCTCTGGCCACATCTGCTGCCTTGATGAACATCCGAATCCTTCACATT
GAAGGTGGGGAAGTCAGTGGGACCATTGATGACTCTATCAGACATGCCATAACAAAACTGGCTCATTATCATGTGTGCTGCACCCGCAGT
GCAGAGCAGCACCTGATATCCATGTGTGAGGACCATGATCGCATCCTTTTGGCAGGCTGCCCTTCCTATGACAAACTTCTCTCAGCCAAG
AACAAAGACTACATGAGCATCATTCGCATGTGGCTAGGTGATGATGTAAAATCTAAAGATTACATTGTTGCACTACAGCACCCTGTGACC
ACTGACATTAAGCATTCCATAAAAATGTTTGAATTAACATTGGATGCACTTATCTCATTTAACAAGCGGACCCTAGTCCTGTTTCCAAAT
ATTGACGCAGGATGGATTGGATGCTTTGGTATATGATTTGGATTTTCCTGCCTTAAGAAAAAACAAAAATATTGACAACTTTTTAAGCAG
ATATAAAGACACAATAAATAAAATCAGAGATTTACGAATGAAAGCTGAAGATTATGAAGTAGTGAAGGTGATTGGTAGAGGTGCATTTGG
AGAAGTTCAATTGGTAAGGCATAAATCCACCAGGAAGGTATATGCTATGAAGCTTCTCAGCAAATTTGAAATGATAAAGAGATCTGATTC
TGCTTTTTTCTGGGAAGAAAGGGACATCATGGCTTTTGCCAACAGTCCTTGGGTTGTTCAGCTTTTTTATGCATTCCAAGATGATCGTTA
TCTCTACATGGTGATGGAATACATGCCTGGTGGAGATCTTGTAAACTTAATGAGCAACTATGATGTGCCTGAAAAATGGGCACGATTCTA
TACTGCAGAAGTAGTTCTTGCATTGGATGCAATCCATTCCATGGGTTTTATTCACAGAGATGTGAAGCCTGATAACATGCTGCTGGATAA
ATCTGGACATTTGAAGTTAGCAGATTTTGGTACTTGTATGAAGATGAATAAGGAAGGCATGGTACGATGTGATACAGCGGTTGGAACACC
TGATTATATTTCCCCTGAAGTATTAAAATCCCAAGGTGGTGATGGTTATTATGGAAGAGAATGTGACTGGTGGTCGGTTGGGGTATTTTT
ATACGAAATGCTTGTAGGTGATACACCTTTTTATGCAGATTCTTTGGTTGGAACTTACAGTAAAATTATGAACCATAAAAATTCACTTAC
CTTTCCTGATGATAATGACATATCAAAAGAAGCAAAAAACCTTATTTGTGCCTTCCTTACTGACAGGGAAGTGAGGTTAGGGCGAAATGG
TGTAGAAGAAATCAAACGACATCTCTTCTTCAAAAATGACCAGTGGGCTTGGGAAACGCTCCGAGACACTGTAGCACCAGTTGTACCCGA
TTTAAGTAGTGACATTGATACTAGTAATTTTGATGACTTGGAAGAAGATAAAGGAGAGGAAGAAACATTCCCTATTCCTAAAGCTTTCGT
TGGCAATCAACTACCTTTTGTAGGATTTACATATTATAGCAATCGTAGATACTTATCTTCAGCAAATCCTAATGATAACAGAACTAGCTC
CAATGCAGATAAAAGCTTGCAGGAAAGTTTGCAAAAAACAATCTATAAGCTGGAAGAACAGCTGCATAATGAAATGCAGTTAAAAGATGA
AATGGAGCAGAAGTGCAGAACCTCAAACATAAAACTAGACAAGATAATGAAAGAATTGGATGAAGAGGGAAATCAAAGAAGAAATCTAGA
ATCTACAGTGTCTCAGATTGAGAAGGAGAAAATGTTGCTACAGCATAGAATTAATGAGTACCAAAGAAAAGCTGAACAGGAAAATGAGAA
GAGAAGAAATGTAGAAAATGAAGTTTCTACATTAAAGGATCAGTTGGAAGACTTAAAGAAAGTCAGTCAGAATTCACAGCTTGCTAATGA
GAAGCTGTCCCAGTTACAAAAGCAGCTAGAAGAAGCCAATGACTTACTTAGGACAGAATCGGACACAGCTGTAAGATTGAGGAAGAGTCA
CACAGAGATGAGCAAGTCAATTAGTCAGTTAGAGTCCCTGAACAGAGAGTTGCAAGAGAGAAATCGAATTTTAGAGAATTCTAAGTCACA
AACAGACAAAGATTATTACCAGCTGCAAGCTATATTAGAAGCTGAACGAAGAGACAGAGGTCATGATTCTGAGATGATTGGAGACCTTCA
AGCTCGAATTACATCTTTACAAGAGGAGGTGAAGCATCTCAAACATAATCTCGAAAAAGTGGAAGGAGAAAGAAAAGAGGCTCAAGACAT
GCTTAATCACTCAGAAAAGGAAAAGAATAATTTAGAGATAGATTTAAACTACAAACTTAAATCATTACAACAACGGTTAGAACAAGAGGT
AAATGAACACAAAGTAACCAAAGCTCGTTTAACTGACAAACATCAATCTATTGAAGAGGCAAAGTCTGTGGCAATGTGTGAGATGGAAAA
AAAGCTGAAAGAAGAAAGAGAAGCTCGAGAGAAGGCTGAAAATCGGGTTGTTCAGATTGAGAAACAGTGTTCCATGCTAGACGTTGATCT
GAAGCAATCTCAGCAGAAACTAGAACATTTGACTGGAAATAAAGAAAGGATGGAGGATGAAGTTAAGAATCTAACCCTGCAACTGGAGCA
GGAATCAAATAAGCGGCTGTTGTTACAAAATGAATTGAAGACTCAAGCATTTGAGGCAGACAATTTAAAAGGTTTAGAAAAGCAGATGAA
ACAGGAAATAAATACTTTATTGGAAGCAAAGAGATTATTAGAATTTGAGTTAGCTCAGCTTACGAAACAGTATAGAGGAAATGAAGGACA
GATGCGGGAGCTACAAGATCAGCTTGAAGCTGAGCAATATTTCTCGACACTTTATAAAACCCAGGTAAAGGAACTTAAAGAAGAAATTGA
AGAAAAAAACAGAGAAAATTTAAAGAAAATACAGGAACTACAAAATGAAAAAGAAACTCTTGCTACTCAGTTGGATCTAGCAGAAACAAA
AGCTGAGTCTGAGCAGTTGGCGCGAGGCCTTCTGGAAGAACAGTATTTTGAATTGACGCAAGAAAGCAAGAAAGCTGCTTCAAGAAATAG
ACAAGAGATTACAGATAAAGATCACACTGTTAGTCGGCTTGAAGAAGCAAACAGCATGCTAACCAAAGATATTGAAATATTAAGAAGAGA
GAATGAAGAGCTAACAGAGAAAATGAAGAAGGCAGAGGAAGAATATAAACTGGAGAAGGAGGAGGAGATCAGTAATCTTAAGGCTGCCTT
TGAAAAGAATATCAACACTGAACGAACCCTTAAAACACAGGCTGTTAACAAATTGGCAGAAATAATGAATCGAAAAGATTTTAAAATTGA
TAGAAAGAAAGCTAATACACAAGATTTGAGAAAGAAAGAAAAGGAAAATCGAAAGCTGCAACTGGAACTCAACCAAGAAAGAGAGAAATT
CAACCAGATGGTAGTGAAACATCAGAAGGAACTGAATGACATGCAAGCGCAATTGGTAGAAGAATGTGCACATAGGAATGAGCTTCAGAT
GCAGTTGGCCAGCAAAGAGAGTGATATTGAGCAATTGCGTGCTAAACTTTTGGACCTCTCGGATTCTACAAGTGTTGCTAGTTTTCCTAG
TGCTGATGAAACTGATGGTAACCTCCCAGAGTCAAGAATTGAAGGTTGGCTTTCAGTACCAAATAGAGGAAATATCAAACGATATGGCTG
GAAGAAACAGTATGTTGTGGTAAGCAGCAAAAAAATTTTGTTCTATAATGACGAACAAGATAAGGAGCAATCCAATCCATCTATGGTATT
GGACATAGATAAACTGTTTCACGTTAGACCTGTAACCCAAGGAGATGTGTATAGAGCTGAAACTGAAGAAATTCCTAAAATATTCCAGAT
ACTATATGCAAATGAAGGTGAATGTAGAAAAGATGTAGAGATGGAACCAGTACAACAAGCTGAAAAAACTAATTTCCAAAATCACAAAGG
CCATGAGTTTATTCCTACACTCTACCACTTTCCTGCCAATTGTGATGCCTGTGCCAAACCTCTCTGGCATGTTTTTAAGCCACCCCCTGC
CCTAGAGTGTCGAAGATGCCATGTTAAGTGCCACAGAGATCACTTAGATAAGAAAGAGGACTTAATTTGTCCATGTAAAGTAAGTTATGA
TGTAACATCAGCAAGAGATATGCTGCTGTTAGCATGTTCTCAGGATGAACAAAAAAAATGGGTAACTCATTTAGTAAAGAAAATCCCTAA
GAATCCACCATCTGGTTTTGTTCGTGCTTCCCCTCGAACGCTTTCTACAAGATCCACTGCAAATCAGTCTTTCCGGAAAGTGGTCAAAAA
TACATCTGGAAAAACTAGTTAACCATGTGACTGAGTGCCCTGTGGAATCGTGTGGGATGCTACCTGATAAACCAGGCTTCTTTAACCATG
CAGAGCAGACAGGCTGTTTCTTTGACACAAATATCACAGGCTTCAGGGTTAAGATTGCTGTTTTTCTGTCCTTGCTTTGGCACAACACAC
TGAGGGTTTTTTTTATTGCGGGTTTGCCTACAGGTAGATTAGATTAATTATTACTATGTAATGCAAGTACAGTTGGGGGAAAGCTTAGGT
AGATATATTTTTTTTAAAAGGTGCTGCCTTTTTGGATTTATAAGAAAATGCCTGTCAGTCGTGATAGAACAGAGTTTTCCTCATATGAGT
AAGAGGAAGGGACTTTCACTTTCAAGTGGAACAGCCATCACTATCAAGATCAGCTCATGGAAGGAGTAAAGAAAATATCTCAAAATGAGA
CAAACTGAAGTTTTGTTTTTTTTTTAATGACTTAAGTTTTTGTGCTCTTGCAAGACTATACAAAACTATTTTAAGAAAGCAGTGATATCA
CTTGAACTTCAGTGCCCTCACTGTAGAATTTAAAAGCCTTACTGTTGATTGCCCATGTTGGACTTGATGGAGAAATTAAATATCTTTCAT
TATGCTTTACAAAATACTGTATATGTTTCAGCAAGTTTGGGGAATGGGAGAGGACAAAAAAAAGTTACATTTAATCTATGCATTTTTGCC
AAGCCATATTGAGTTATTTTACTACTAGAGACATTAGGAAACTAACTGTACAAAAGAACCAAGTTTAAAAGCATTTTGTGGGGTACATCA
TTTCTATAATTGTATAATGTATTTCTTTGTGGTTTTAAATGATAAAGACATTAAGTTAACAAACATATAAGAAATGTATGCACTGTTTGA
AATGTAAATTATTCTTAGAACACTTTCAATGGGGGTTGCATTGTCCTTTTAGTGCCTTAATTTGAGATAATTATTTTACTGCCATGAGTA
AGTATAGAAATTTCAAAAAATGTATTTTCAAAAAATTATGTGTGTCAGTGAGTTTTTCATTGATAATTGGTTTAATTTAAAATATTTAGA
GGTTTGTTGGACTTTCATAAATTGAGTACAATCTTTGCATCAAACTACCTGCTACAATAATGACTTTATAAAACTGCAAAAAATGTAGAA
GGTTGCACCAACATAAAAAGGAAATATGGCAATACATCCATGATGTTTTCCAGTTAACATAGGAATTACCAGATAAATACTGTTAAACTC
TTGTCCAGTAACAAGAGTTGATTCATATGGACAGTATGATTTATTGTTTATTTTTTTAACCAAATACCTCCTCAGTAATTTATAATGGCT
TTGCAGTAATGTGTATCAGATAAGAAGCACTGGAAAACCGATCGTCTCTAGGATGATATGCATGTTTCAAGTGGTATTGAAAGCCGCACT
GATGGATATGTAATAATAAACATATCTGTTATTAATATACTAATGACTCTGTGCTCATTTAATGAGAAATAAAAGTAATTTATGGATGGG
TATCTTTAATTTTTACTGCAATGTGTTTTCTCATGGCTGAAATGAATGGAAAACATACTTCAAATTAGTCTCTGATTGTATATAAATGTT
TGTGAAATTCCATGGTTAGATTAAAGTGTATTTTTAAAAGATAAAACGTGGTCTTGGGCTCTAAAACAAGAGTGGGAATAGTTCACATGA
AAAGCTGGCTAAAGTGTGTTGGAAAACAATTCTCCATGGGTCTCTTGCATTTCTACACATCAGGGAAGCAGAGGCTCTGACAACCTTTCT
TTTGACTATCTTTTCCAAGGATATTTATGTAGTAAACAGCCTTGGAAGATAGAGTTCTCCCTTGTGAGGATGTCGGGTTCTTTTACTGTC
CAGTATAATAAAGATAACGTCTCCCACCTATGATGCAAACCCACTGTGTGCTCAGCACCCACCTGGGCCACTCTGCATTGCCCACATGGG
GCTTGGAGGGCAAAGGGAACTGATGGAACGTGAAACTTATGCTGCTTTTGCTGTGCTGTGAATGAAGTCATCTGACTCTGACCCAGGGGT
CTCATCTCTTTTGTCAGGATCCATGAAACTGTGACTGGCAGCATGCAAACAGGATAAAATCTCAGCACAGTTCCTGACGGTGTCCTTACT
ACCTTCTCAGACTCATCACCATTACCTAATATTTTAAGGTCCAGTTGCAGAGAACAGAGTTAATTCTAATTAGTTTAAGCAAGAGAAGAC
TTTCCAAATGACATACTAATCTGAACTTAGAATTGTTGAGAACTGAGAGAGCTTTGAGGAATCACTCCCAATGCCACATTACAGAACTGG
GTCAACCAGGAGAGCTGCTTCCTCTTCTAAGTTCAGGAAACCACTCACTCCCAAGTATACCAATATTGAGAGGGTCCAGATAGTGCCATA
ATCAGGAATCCACACTACCACTGCTGGTTCTCTGCAACACTTGTCAGGCTTGCTACAATCTACCTCCAGTTAGATGTTTTGTACCATTCC
TCTTGCCACTTAAGAACCTCATGTCTGCACACTGCCTCAGAAAAGGCACTTCCATGACCCTGCTTGCTGGCATTTAGCACAGCCTGCATC
TCACGTCTGCCTTCTCTAGGTGCATCTACGTGGCCAAAATTAAATCACATCCAGACCCCTAGCTGCAAGAAAGTCTGAGAAATATAGCCT
CTAGCTTTCTCTCTAATTTGTTACAGGAGGACACACTAGGAGTGTGGAATGAAGGTTCAGCATTGAGTTAGCCCATGCACCCACACCTGT
AAGCTTCTCTGAGATCAGGAACTCCAGCTTTGGGCAACAAAGAAAACATAGCCACTGTCATTATTCACAGGTTCACTCATGACCTGTCAT
TTGGGGTTTCAGCTTAAATTAACCCATTCACCCTTCATTTAAAGTAAAAAAAATAAGTAAAAGAACTTAAATGACAAACTCATAGTTACT
TGAGTTTGTAATTCATAGTTAACTTTCACAGTTCTATAATCAATCTGGAATTCAGAGTGAGGTAGAGATCAAGCAGTATTTCTCCCATAT
GGATATTCAGTTGATACTGCAGTATTCATTGAAAATACTTCTTTCCTGCATCGTAATTCAGGTGAACAATCCATTGGTGTTATTTCTGTG
TCCTTGCCAATATCACACTTTTAATTACTGTAACTTTATAATAAGATTTTATATCTGTAGTAGAAGTCCAACTTTGTAATCCCTCCCAAT
TGGCTTGGCTATTCTTGGCCTTTTGCATTTCCATATAATTTTTTATTTTTGTTTTGAAACGAAGTTTCGCTCTTGTTGCCCAGGCTGGAG
TGCAGTGGCGCGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATCCTCCTGCCTCAGACTCCCGAGTAGCTGGGATTACA
GGTGCCCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGCCTGGTCTTGAACTCCTGACC
TCAGGTGATCCACACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCTGGTTGCATTCCCATATAAATTTAA
AAACAATCTACTGAAAGATGTATACGACCTCCACCAAGAAAATTGTAAGACATTTGGAGAAGTTTAAAAAGACATGAATAAACGGAAATG
GTTTTTTTAAATAAACAAATGATTTTTAAAGTTGATCATTAGGTTAATAAATAGTCATATAATGACAATCCGATGAGATTATGTTGCCCA
GGGTGGTCTCTAACTCCTAGCCTCAAGCAGTTTTACTCTCTCATTACAGGTGTAGGCCACCGTGCCTGGCCTGACACTTGGAAATCTTAA
TCACAATTATTCTTTGTTTTTATAATGTTTACTGTTCAAATCAATTTCTGGTTGGATAGTATGTATATATAAAGCCATGCTCAATGGCCT
AGATATATTTACTGCCAAATCTTTTATGCTTTTAGTGTTTTTTTTCTGGACAAGATCTATGCTTATTGCAATAAATTAAATGCAAAGAAT
ATTCTAGTAGAAAGTCAGTCTGCACTTCCTAAACCCCACCCCACCCCACCAATTCCTTCATAACTGTTATTAACAGTTAGCTGTGTTTTC
TAATGGATTATCTCCAAAGTATATGTAACTCAGATTTTTGTGAGGTAGGAAAAGAATAACATTAATTCCACTTCACATATTGAAAGTCTA
ACATACAAAGAGATTAAATATCTCCTTTCTTTTGCCAAATGTTAATGAATTGTCTTATGAGAATTAAGATATGATACTTTCTCCCAAGCT
ATACTGTTTCCCATAAAGTATTTGAGATGTTGGAGATTCAAGGGAAAAAATATAAATGCTTAGAAATAAAGTGTATAATGCAAAGATTGT
GAATAAAGTGACACTTGTATGTTAATCCTATAAATTGGTTTCTTGTACCATGTAGGATGGTTTGGCTATTAAATTGAATTAAGTGGTTCA

>33729_33729_2_GNE-ROCK1_GNE_chr9_36236828_ENST00000447283_ROCK1_chr18_18650574_ENST00000399799_length(amino acids)=1326AA_BP=3
MTQDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDS
AFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDK
SGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLT
FPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIPKAFV
GNQLPFVGFTYYSNRRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLE
STVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSH
TEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDM
LNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDL
KQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQ
MRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNR
QEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKID
RKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKLLDLSDSTSVASFPS
ADETDGNLPESRIEGWLSVPNRGNIKRYGWKKQYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQI
LYANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCDACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLICPCKVSYD

--------------------------------------------------------------
>33729_33729_3_GNE-ROCK1_GNE_chr9_36236829_ENST00000377902_ROCK1_chr18_18650574_ENST00000399799_length(transcript)=9440nt_BP=990nt
GTGGGCGTGGCTGGGCGAGCGAGGAGTGGGGACAAGGTCGAGCGACGAGTCGTCTACCCGCGCGCCCGAGCGCGGAAACCGAGGGGCAGG
CTCGCGCTCTGCCTGCTTCGTGGCGCTTGGTTCGTCCCTCGCCCGAGGAGCGCGGTGGCGGCGTGGGAGGGAGCCTCTGACGGCGTCTGG
AACTCTATTTTAAGAACCTCTCAAAACGAAACAAGCAAATCATGGAGAAGAATGGAAATAACCGAAAGCTGCGGGTTTGTGTTGCTACTT
GTAACCGTGCAGATTATTCTAAACTTGCCCCGATCATGTTTGGCATTAAAACCGAACCTGAGTTCTTTGAACTTGATGTTGTGGTACTTG
GCTCTCACCTGATAGATGACTATGGAAATACATATCGAATGATTGAACAAGATGACTTTGACATTAACACCAGGCTACACACAATTGTGA
GGGGAGAAGATGAGGCAGCCATGGTGGAGTCAGTAGGCCTGGCCCTAGTGAAGCTGCCAGATGTCCTTAATCGCCTGAAGCCTGATATCA
TGATTGTTCATGGAGACAGGTTTGATGCCCTGGCTCTGGCCACATCTGCTGCCTTGATGAACATCCGAATCCTTCACATTGAAGGTGGGG
AAGTCAGTGGGACCATTGATGACTCTATCAGACATGCCATAACAAAACTGGCTCATTATCATGTGTGCTGCACCCGCAGTGCAGAGCAGC
ACCTGATATCCATGTGTGAGGACCATGATCGCATCCTTTTGGCAGGCTGCCCTTCCTATGACAAACTTCTCTCAGCCAAGAACAAAGACT
ACATGAGCATCATTCGCATGTGGCTAGGTGATGATGTAAAATCTAAAGATTACATTGTTGCACTACAGCACCCTGTGACCACTGACATTA
AGCATTCCATAAAAATGTTTGAATTAACATTGGATGCACTTATCTCATTTAACAAGCGGACCCTAGTCCTGTTTCCAAATATTGACGCAG
GATGGATTGGATGCTTTGGTATATGATTTGGATTTTCCTGCCTTAAGAAAAAACAAAAATATTGACAACTTTTTAAGCAGATATAAAGAC
ACAATAAATAAAATCAGAGATTTACGAATGAAAGCTGAAGATTATGAAGTAGTGAAGGTGATTGGTAGAGGTGCATTTGGAGAAGTTCAA
TTGGTAAGGCATAAATCCACCAGGAAGGTATATGCTATGAAGCTTCTCAGCAAATTTGAAATGATAAAGAGATCTGATTCTGCTTTTTTC
TGGGAAGAAAGGGACATCATGGCTTTTGCCAACAGTCCTTGGGTTGTTCAGCTTTTTTATGCATTCCAAGATGATCGTTATCTCTACATG
GTGATGGAATACATGCCTGGTGGAGATCTTGTAAACTTAATGAGCAACTATGATGTGCCTGAAAAATGGGCACGATTCTATACTGCAGAA
GTAGTTCTTGCATTGGATGCAATCCATTCCATGGGTTTTATTCACAGAGATGTGAAGCCTGATAACATGCTGCTGGATAAATCTGGACAT
TTGAAGTTAGCAGATTTTGGTACTTGTATGAAGATGAATAAGGAAGGCATGGTACGATGTGATACAGCGGTTGGAACACCTGATTATATT
TCCCCTGAAGTATTAAAATCCCAAGGTGGTGATGGTTATTATGGAAGAGAATGTGACTGGTGGTCGGTTGGGGTATTTTTATACGAAATG
CTTGTAGGTGATACACCTTTTTATGCAGATTCTTTGGTTGGAACTTACAGTAAAATTATGAACCATAAAAATTCACTTACCTTTCCTGAT
GATAATGACATATCAAAAGAAGCAAAAAACCTTATTTGTGCCTTCCTTACTGACAGGGAAGTGAGGTTAGGGCGAAATGGTGTAGAAGAA
ATCAAACGACATCTCTTCTTCAAAAATGACCAGTGGGCTTGGGAAACGCTCCGAGACACTGTAGCACCAGTTGTACCCGATTTAAGTAGT
GACATTGATACTAGTAATTTTGATGACTTGGAAGAAGATAAAGGAGAGGAAGAAACATTCCCTATTCCTAAAGCTTTCGTTGGCAATCAA
CTACCTTTTGTAGGATTTACATATTATAGCAATCGTAGATACTTATCTTCAGCAAATCCTAATGATAACAGAACTAGCTCCAATGCAGAT
AAAAGCTTGCAGGAAAGTTTGCAAAAAACAATCTATAAGCTGGAAGAACAGCTGCATAATGAAATGCAGTTAAAAGATGAAATGGAGCAG
AAGTGCAGAACCTCAAACATAAAACTAGACAAGATAATGAAAGAATTGGATGAAGAGGGAAATCAAAGAAGAAATCTAGAATCTACAGTG
TCTCAGATTGAGAAGGAGAAAATGTTGCTACAGCATAGAATTAATGAGTACCAAAGAAAAGCTGAACAGGAAAATGAGAAGAGAAGAAAT
GTAGAAAATGAAGTTTCTACATTAAAGGATCAGTTGGAAGACTTAAAGAAAGTCAGTCAGAATTCACAGCTTGCTAATGAGAAGCTGTCC
CAGTTACAAAAGCAGCTAGAAGAAGCCAATGACTTACTTAGGACAGAATCGGACACAGCTGTAAGATTGAGGAAGAGTCACACAGAGATG
AGCAAGTCAATTAGTCAGTTAGAGTCCCTGAACAGAGAGTTGCAAGAGAGAAATCGAATTTTAGAGAATTCTAAGTCACAAACAGACAAA
GATTATTACCAGCTGCAAGCTATATTAGAAGCTGAACGAAGAGACAGAGGTCATGATTCTGAGATGATTGGAGACCTTCAAGCTCGAATT
ACATCTTTACAAGAGGAGGTGAAGCATCTCAAACATAATCTCGAAAAAGTGGAAGGAGAAAGAAAAGAGGCTCAAGACATGCTTAATCAC
TCAGAAAAGGAAAAGAATAATTTAGAGATAGATTTAAACTACAAACTTAAATCATTACAACAACGGTTAGAACAAGAGGTAAATGAACAC
AAAGTAACCAAAGCTCGTTTAACTGACAAACATCAATCTATTGAAGAGGCAAAGTCTGTGGCAATGTGTGAGATGGAAAAAAAGCTGAAA
GAAGAAAGAGAAGCTCGAGAGAAGGCTGAAAATCGGGTTGTTCAGATTGAGAAACAGTGTTCCATGCTAGACGTTGATCTGAAGCAATCT
CAGCAGAAACTAGAACATTTGACTGGAAATAAAGAAAGGATGGAGGATGAAGTTAAGAATCTAACCCTGCAACTGGAGCAGGAATCAAAT
AAGCGGCTGTTGTTACAAAATGAATTGAAGACTCAAGCATTTGAGGCAGACAATTTAAAAGGTTTAGAAAAGCAGATGAAACAGGAAATA
AATACTTTATTGGAAGCAAAGAGATTATTAGAATTTGAGTTAGCTCAGCTTACGAAACAGTATAGAGGAAATGAAGGACAGATGCGGGAG
CTACAAGATCAGCTTGAAGCTGAGCAATATTTCTCGACACTTTATAAAACCCAGGTAAAGGAACTTAAAGAAGAAATTGAAGAAAAAAAC
AGAGAAAATTTAAAGAAAATACAGGAACTACAAAATGAAAAAGAAACTCTTGCTACTCAGTTGGATCTAGCAGAAACAAAAGCTGAGTCT
GAGCAGTTGGCGCGAGGCCTTCTGGAAGAACAGTATTTTGAATTGACGCAAGAAAGCAAGAAAGCTGCTTCAAGAAATAGACAAGAGATT
ACAGATAAAGATCACACTGTTAGTCGGCTTGAAGAAGCAAACAGCATGCTAACCAAAGATATTGAAATATTAAGAAGAGAGAATGAAGAG
CTAACAGAGAAAATGAAGAAGGCAGAGGAAGAATATAAACTGGAGAAGGAGGAGGAGATCAGTAATCTTAAGGCTGCCTTTGAAAAGAAT
ATCAACACTGAACGAACCCTTAAAACACAGGCTGTTAACAAATTGGCAGAAATAATGAATCGAAAAGATTTTAAAATTGATAGAAAGAAA
GCTAATACACAAGATTTGAGAAAGAAAGAAAAGGAAAATCGAAAGCTGCAACTGGAACTCAACCAAGAAAGAGAGAAATTCAACCAGATG
GTAGTGAAACATCAGAAGGAACTGAATGACATGCAAGCGCAATTGGTAGAAGAATGTGCACATAGGAATGAGCTTCAGATGCAGTTGGCC
AGCAAAGAGAGTGATATTGAGCAATTGCGTGCTAAACTTTTGGACCTCTCGGATTCTACAAGTGTTGCTAGTTTTCCTAGTGCTGATGAA
ACTGATGGTAACCTCCCAGAGTCAAGAATTGAAGGTTGGCTTTCAGTACCAAATAGAGGAAATATCAAACGATATGGCTGGAAGAAACAG
TATGTTGTGGTAAGCAGCAAAAAAATTTTGTTCTATAATGACGAACAAGATAAGGAGCAATCCAATCCATCTATGGTATTGGACATAGAT
AAACTGTTTCACGTTAGACCTGTAACCCAAGGAGATGTGTATAGAGCTGAAACTGAAGAAATTCCTAAAATATTCCAGATACTATATGCA
AATGAAGGTGAATGTAGAAAAGATGTAGAGATGGAACCAGTACAACAAGCTGAAAAAACTAATTTCCAAAATCACAAAGGCCATGAGTTT
ATTCCTACACTCTACCACTTTCCTGCCAATTGTGATGCCTGTGCCAAACCTCTCTGGCATGTTTTTAAGCCACCCCCTGCCCTAGAGTGT
CGAAGATGCCATGTTAAGTGCCACAGAGATCACTTAGATAAGAAAGAGGACTTAATTTGTCCATGTAAAGTAAGTTATGATGTAACATCA
GCAAGAGATATGCTGCTGTTAGCATGTTCTCAGGATGAACAAAAAAAATGGGTAACTCATTTAGTAAAGAAAATCCCTAAGAATCCACCA
TCTGGTTTTGTTCGTGCTTCCCCTCGAACGCTTTCTACAAGATCCACTGCAAATCAGTCTTTCCGGAAAGTGGTCAAAAATACATCTGGA
AAAACTAGTTAACCATGTGACTGAGTGCCCTGTGGAATCGTGTGGGATGCTACCTGATAAACCAGGCTTCTTTAACCATGCAGAGCAGAC
AGGCTGTTTCTTTGACACAAATATCACAGGCTTCAGGGTTAAGATTGCTGTTTTTCTGTCCTTGCTTTGGCACAACACACTGAGGGTTTT
TTTTATTGCGGGTTTGCCTACAGGTAGATTAGATTAATTATTACTATGTAATGCAAGTACAGTTGGGGGAAAGCTTAGGTAGATATATTT
TTTTTAAAAGGTGCTGCCTTTTTGGATTTATAAGAAAATGCCTGTCAGTCGTGATAGAACAGAGTTTTCCTCATATGAGTAAGAGGAAGG
GACTTTCACTTTCAAGTGGAACAGCCATCACTATCAAGATCAGCTCATGGAAGGAGTAAAGAAAATATCTCAAAATGAGACAAACTGAAG
TTTTGTTTTTTTTTTAATGACTTAAGTTTTTGTGCTCTTGCAAGACTATACAAAACTATTTTAAGAAAGCAGTGATATCACTTGAACTTC
AGTGCCCTCACTGTAGAATTTAAAAGCCTTACTGTTGATTGCCCATGTTGGACTTGATGGAGAAATTAAATATCTTTCATTATGCTTTAC
AAAATACTGTATATGTTTCAGCAAGTTTGGGGAATGGGAGAGGACAAAAAAAAGTTACATTTAATCTATGCATTTTTGCCAAGCCATATT
GAGTTATTTTACTACTAGAGACATTAGGAAACTAACTGTACAAAAGAACCAAGTTTAAAAGCATTTTGTGGGGTACATCATTTCTATAAT
TGTATAATGTATTTCTTTGTGGTTTTAAATGATAAAGACATTAAGTTAACAAACATATAAGAAATGTATGCACTGTTTGAAATGTAAATT
ATTCTTAGAACACTTTCAATGGGGGTTGCATTGTCCTTTTAGTGCCTTAATTTGAGATAATTATTTTACTGCCATGAGTAAGTATAGAAA
TTTCAAAAAATGTATTTTCAAAAAATTATGTGTGTCAGTGAGTTTTTCATTGATAATTGGTTTAATTTAAAATATTTAGAGGTTTGTTGG
ACTTTCATAAATTGAGTACAATCTTTGCATCAAACTACCTGCTACAATAATGACTTTATAAAACTGCAAAAAATGTAGAAGGTTGCACCA
ACATAAAAAGGAAATATGGCAATACATCCATGATGTTTTCCAGTTAACATAGGAATTACCAGATAAATACTGTTAAACTCTTGTCCAGTA
ACAAGAGTTGATTCATATGGACAGTATGATTTATTGTTTATTTTTTTAACCAAATACCTCCTCAGTAATTTATAATGGCTTTGCAGTAAT
GTGTATCAGATAAGAAGCACTGGAAAACCGATCGTCTCTAGGATGATATGCATGTTTCAAGTGGTATTGAAAGCCGCACTGATGGATATG
TAATAATAAACATATCTGTTATTAATATACTAATGACTCTGTGCTCATTTAATGAGAAATAAAAGTAATTTATGGATGGGTATCTTTAAT
TTTTACTGCAATGTGTTTTCTCATGGCTGAAATGAATGGAAAACATACTTCAAATTAGTCTCTGATTGTATATAAATGTTTGTGAAATTC
CATGGTTAGATTAAAGTGTATTTTTAAAAGATAAAACGTGGTCTTGGGCTCTAAAACAAGAGTGGGAATAGTTCACATGAAAAGCTGGCT
AAAGTGTGTTGGAAAACAATTCTCCATGGGTCTCTTGCATTTCTACACATCAGGGAAGCAGAGGCTCTGACAACCTTTCTTTTGACTATC
TTTTCCAAGGATATTTATGTAGTAAACAGCCTTGGAAGATAGAGTTCTCCCTTGTGAGGATGTCGGGTTCTTTTACTGTCCAGTATAATA
AAGATAACGTCTCCCACCTATGATGCAAACCCACTGTGTGCTCAGCACCCACCTGGGCCACTCTGCATTGCCCACATGGGGCTTGGAGGG
CAAAGGGAACTGATGGAACGTGAAACTTATGCTGCTTTTGCTGTGCTGTGAATGAAGTCATCTGACTCTGACCCAGGGGTCTCATCTCTT
TTGTCAGGATCCATGAAACTGTGACTGGCAGCATGCAAACAGGATAAAATCTCAGCACAGTTCCTGACGGTGTCCTTACTACCTTCTCAG
ACTCATCACCATTACCTAATATTTTAAGGTCCAGTTGCAGAGAACAGAGTTAATTCTAATTAGTTTAAGCAAGAGAAGACTTTCCAAATG
ACATACTAATCTGAACTTAGAATTGTTGAGAACTGAGAGAGCTTTGAGGAATCACTCCCAATGCCACATTACAGAACTGGGTCAACCAGG
AGAGCTGCTTCCTCTTCTAAGTTCAGGAAACCACTCACTCCCAAGTATACCAATATTGAGAGGGTCCAGATAGTGCCATAATCAGGAATC
CACACTACCACTGCTGGTTCTCTGCAACACTTGTCAGGCTTGCTACAATCTACCTCCAGTTAGATGTTTTGTACCATTCCTCTTGCCACT
TAAGAACCTCATGTCTGCACACTGCCTCAGAAAAGGCACTTCCATGACCCTGCTTGCTGGCATTTAGCACAGCCTGCATCTCACGTCTGC
CTTCTCTAGGTGCATCTACGTGGCCAAAATTAAATCACATCCAGACCCCTAGCTGCAAGAAAGTCTGAGAAATATAGCCTCTAGCTTTCT
CTCTAATTTGTTACAGGAGGACACACTAGGAGTGTGGAATGAAGGTTCAGCATTGAGTTAGCCCATGCACCCACACCTGTAAGCTTCTCT
GAGATCAGGAACTCCAGCTTTGGGCAACAAAGAAAACATAGCCACTGTCATTATTCACAGGTTCACTCATGACCTGTCATTTGGGGTTTC
AGCTTAAATTAACCCATTCACCCTTCATTTAAAGTAAAAAAAATAAGTAAAAGAACTTAAATGACAAACTCATAGTTACTTGAGTTTGTA
ATTCATAGTTAACTTTCACAGTTCTATAATCAATCTGGAATTCAGAGTGAGGTAGAGATCAAGCAGTATTTCTCCCATATGGATATTCAG
TTGATACTGCAGTATTCATTGAAAATACTTCTTTCCTGCATCGTAATTCAGGTGAACAATCCATTGGTGTTATTTCTGTGTCCTTGCCAA
TATCACACTTTTAATTACTGTAACTTTATAATAAGATTTTATATCTGTAGTAGAAGTCCAACTTTGTAATCCCTCCCAATTGGCTTGGCT
ATTCTTGGCCTTTTGCATTTCCATATAATTTTTTATTTTTGTTTTGAAACGAAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCAGTGGCG
CGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATCCTCCTGCCTCAGACTCCCGAGTAGCTGGGATTACAGGTGCCCACC
ACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGCCTGGTCTTGAACTCCTGACCTCAGGTGATC
CACACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCTGGTTGCATTCCCATATAAATTTAAAAACAATCTA
CTGAAAGATGTATACGACCTCCACCAAGAAAATTGTAAGACATTTGGAGAAGTTTAAAAAGACATGAATAAACGGAAATGGTTTTTTTAA
ATAAACAAATGATTTTTAAAGTTGATCATTAGGTTAATAAATAGTCATATAATGACAATCCGATGAGATTATGTTGCCCAGGGTGGTCTC
TAACTCCTAGCCTCAAGCAGTTTTACTCTCTCATTACAGGTGTAGGCCACCGTGCCTGGCCTGACACTTGGAAATCTTAATCACAATTAT
TCTTTGTTTTTATAATGTTTACTGTTCAAATCAATTTCTGGTTGGATAGTATGTATATATAAAGCCATGCTCAATGGCCTAGATATATTT
ACTGCCAAATCTTTTATGCTTTTAGTGTTTTTTTTCTGGACAAGATCTATGCTTATTGCAATAAATTAAATGCAAAGAATATTCTAGTAG
AAAGTCAGTCTGCACTTCCTAAACCCCACCCCACCCCACCAATTCCTTCATAACTGTTATTAACAGTTAGCTGTGTTTTCTAATGGATTA
TCTCCAAAGTATATGTAACTCAGATTTTTGTGAGGTAGGAAAAGAATAACATTAATTCCACTTCACATATTGAAAGTCTAACATACAAAG
AGATTAAATATCTCCTTTCTTTTGCCAAATGTTAATGAATTGTCTTATGAGAATTAAGATATGATACTTTCTCCCAAGCTATACTGTTTC
CCATAAAGTATTTGAGATGTTGGAGATTCAAGGGAAAAAATATAAATGCTTAGAAATAAAGTGTATAATGCAAAGATTGTGAATAAAGTG

>33729_33729_3_GNE-ROCK1_GNE_chr9_36236829_ENST00000377902_ROCK1_chr18_18650574_ENST00000399799_length(amino acids)=1326AA_BP=3
MTQDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDS
AFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDK
SGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLT
FPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIPKAFV
GNQLPFVGFTYYSNRRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLE
STVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSH
TEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDM
LNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDL
KQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQ
MRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNR
QEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKID
RKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKLLDLSDSTSVASFPS
ADETDGNLPESRIEGWLSVPNRGNIKRYGWKKQYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQI
LYANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCDACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLICPCKVSYD

--------------------------------------------------------------
>33729_33729_4_GNE-ROCK1_GNE_chr9_36236829_ENST00000447283_ROCK1_chr18_18650574_ENST00000399799_length(transcript)=9270nt_BP=820nt
CGGCGTCTGGAACTCTATTTTAAGAACCTCTCAAAACGAAACAAGCAAATCATGGAGAAGAATGGAAATAACCGAAAGCTGCGGGTTTGT
GTTGCTACTTGTAACCGTGCAGATTATTCTAAACTTGCCCCGATCATGTTTGGCATTAAAACCGAACCTGAGTTCTTTGAACTTGATGTT
GTGGTACTTGGCTCTCACCTGATAGATGACTATGGAAATACATATCGAATGATTGAACAAGATGACTTTGACATTAACACCAGGCTACAC
ACAATTGTGAGGGGAGAAGATGAGGCAGCCATGGTGGAGTCAGTAGGCCTGGCCCTAGTGAAGCTGCCAGATGTCCTTAATCGCCTGAAG
CCTGATATCATGATTGTTCATGGAGACAGGTTTGATGCCCTGGCTCTGGCCACATCTGCTGCCTTGATGAACATCCGAATCCTTCACATT
GAAGGTGGGGAAGTCAGTGGGACCATTGATGACTCTATCAGACATGCCATAACAAAACTGGCTCATTATCATGTGTGCTGCACCCGCAGT
GCAGAGCAGCACCTGATATCCATGTGTGAGGACCATGATCGCATCCTTTTGGCAGGCTGCCCTTCCTATGACAAACTTCTCTCAGCCAAG
AACAAAGACTACATGAGCATCATTCGCATGTGGCTAGGTGATGATGTAAAATCTAAAGATTACATTGTTGCACTACAGCACCCTGTGACC
ACTGACATTAAGCATTCCATAAAAATGTTTGAATTAACATTGGATGCACTTATCTCATTTAACAAGCGGACCCTAGTCCTGTTTCCAAAT
ATTGACGCAGGATGGATTGGATGCTTTGGTATATGATTTGGATTTTCCTGCCTTAAGAAAAAACAAAAATATTGACAACTTTTTAAGCAG
ATATAAAGACACAATAAATAAAATCAGAGATTTACGAATGAAAGCTGAAGATTATGAAGTAGTGAAGGTGATTGGTAGAGGTGCATTTGG
AGAAGTTCAATTGGTAAGGCATAAATCCACCAGGAAGGTATATGCTATGAAGCTTCTCAGCAAATTTGAAATGATAAAGAGATCTGATTC
TGCTTTTTTCTGGGAAGAAAGGGACATCATGGCTTTTGCCAACAGTCCTTGGGTTGTTCAGCTTTTTTATGCATTCCAAGATGATCGTTA
TCTCTACATGGTGATGGAATACATGCCTGGTGGAGATCTTGTAAACTTAATGAGCAACTATGATGTGCCTGAAAAATGGGCACGATTCTA
TACTGCAGAAGTAGTTCTTGCATTGGATGCAATCCATTCCATGGGTTTTATTCACAGAGATGTGAAGCCTGATAACATGCTGCTGGATAA
ATCTGGACATTTGAAGTTAGCAGATTTTGGTACTTGTATGAAGATGAATAAGGAAGGCATGGTACGATGTGATACAGCGGTTGGAACACC
TGATTATATTTCCCCTGAAGTATTAAAATCCCAAGGTGGTGATGGTTATTATGGAAGAGAATGTGACTGGTGGTCGGTTGGGGTATTTTT
ATACGAAATGCTTGTAGGTGATACACCTTTTTATGCAGATTCTTTGGTTGGAACTTACAGTAAAATTATGAACCATAAAAATTCACTTAC
CTTTCCTGATGATAATGACATATCAAAAGAAGCAAAAAACCTTATTTGTGCCTTCCTTACTGACAGGGAAGTGAGGTTAGGGCGAAATGG
TGTAGAAGAAATCAAACGACATCTCTTCTTCAAAAATGACCAGTGGGCTTGGGAAACGCTCCGAGACACTGTAGCACCAGTTGTACCCGA
TTTAAGTAGTGACATTGATACTAGTAATTTTGATGACTTGGAAGAAGATAAAGGAGAGGAAGAAACATTCCCTATTCCTAAAGCTTTCGT
TGGCAATCAACTACCTTTTGTAGGATTTACATATTATAGCAATCGTAGATACTTATCTTCAGCAAATCCTAATGATAACAGAACTAGCTC
CAATGCAGATAAAAGCTTGCAGGAAAGTTTGCAAAAAACAATCTATAAGCTGGAAGAACAGCTGCATAATGAAATGCAGTTAAAAGATGA
AATGGAGCAGAAGTGCAGAACCTCAAACATAAAACTAGACAAGATAATGAAAGAATTGGATGAAGAGGGAAATCAAAGAAGAAATCTAGA
ATCTACAGTGTCTCAGATTGAGAAGGAGAAAATGTTGCTACAGCATAGAATTAATGAGTACCAAAGAAAAGCTGAACAGGAAAATGAGAA
GAGAAGAAATGTAGAAAATGAAGTTTCTACATTAAAGGATCAGTTGGAAGACTTAAAGAAAGTCAGTCAGAATTCACAGCTTGCTAATGA
GAAGCTGTCCCAGTTACAAAAGCAGCTAGAAGAAGCCAATGACTTACTTAGGACAGAATCGGACACAGCTGTAAGATTGAGGAAGAGTCA
CACAGAGATGAGCAAGTCAATTAGTCAGTTAGAGTCCCTGAACAGAGAGTTGCAAGAGAGAAATCGAATTTTAGAGAATTCTAAGTCACA
AACAGACAAAGATTATTACCAGCTGCAAGCTATATTAGAAGCTGAACGAAGAGACAGAGGTCATGATTCTGAGATGATTGGAGACCTTCA
AGCTCGAATTACATCTTTACAAGAGGAGGTGAAGCATCTCAAACATAATCTCGAAAAAGTGGAAGGAGAAAGAAAAGAGGCTCAAGACAT
GCTTAATCACTCAGAAAAGGAAAAGAATAATTTAGAGATAGATTTAAACTACAAACTTAAATCATTACAACAACGGTTAGAACAAGAGGT
AAATGAACACAAAGTAACCAAAGCTCGTTTAACTGACAAACATCAATCTATTGAAGAGGCAAAGTCTGTGGCAATGTGTGAGATGGAAAA
AAAGCTGAAAGAAGAAAGAGAAGCTCGAGAGAAGGCTGAAAATCGGGTTGTTCAGATTGAGAAACAGTGTTCCATGCTAGACGTTGATCT
GAAGCAATCTCAGCAGAAACTAGAACATTTGACTGGAAATAAAGAAAGGATGGAGGATGAAGTTAAGAATCTAACCCTGCAACTGGAGCA
GGAATCAAATAAGCGGCTGTTGTTACAAAATGAATTGAAGACTCAAGCATTTGAGGCAGACAATTTAAAAGGTTTAGAAAAGCAGATGAA
ACAGGAAATAAATACTTTATTGGAAGCAAAGAGATTATTAGAATTTGAGTTAGCTCAGCTTACGAAACAGTATAGAGGAAATGAAGGACA
GATGCGGGAGCTACAAGATCAGCTTGAAGCTGAGCAATATTTCTCGACACTTTATAAAACCCAGGTAAAGGAACTTAAAGAAGAAATTGA
AGAAAAAAACAGAGAAAATTTAAAGAAAATACAGGAACTACAAAATGAAAAAGAAACTCTTGCTACTCAGTTGGATCTAGCAGAAACAAA
AGCTGAGTCTGAGCAGTTGGCGCGAGGCCTTCTGGAAGAACAGTATTTTGAATTGACGCAAGAAAGCAAGAAAGCTGCTTCAAGAAATAG
ACAAGAGATTACAGATAAAGATCACACTGTTAGTCGGCTTGAAGAAGCAAACAGCATGCTAACCAAAGATATTGAAATATTAAGAAGAGA
GAATGAAGAGCTAACAGAGAAAATGAAGAAGGCAGAGGAAGAATATAAACTGGAGAAGGAGGAGGAGATCAGTAATCTTAAGGCTGCCTT
TGAAAAGAATATCAACACTGAACGAACCCTTAAAACACAGGCTGTTAACAAATTGGCAGAAATAATGAATCGAAAAGATTTTAAAATTGA
TAGAAAGAAAGCTAATACACAAGATTTGAGAAAGAAAGAAAAGGAAAATCGAAAGCTGCAACTGGAACTCAACCAAGAAAGAGAGAAATT
CAACCAGATGGTAGTGAAACATCAGAAGGAACTGAATGACATGCAAGCGCAATTGGTAGAAGAATGTGCACATAGGAATGAGCTTCAGAT
GCAGTTGGCCAGCAAAGAGAGTGATATTGAGCAATTGCGTGCTAAACTTTTGGACCTCTCGGATTCTACAAGTGTTGCTAGTTTTCCTAG
TGCTGATGAAACTGATGGTAACCTCCCAGAGTCAAGAATTGAAGGTTGGCTTTCAGTACCAAATAGAGGAAATATCAAACGATATGGCTG
GAAGAAACAGTATGTTGTGGTAAGCAGCAAAAAAATTTTGTTCTATAATGACGAACAAGATAAGGAGCAATCCAATCCATCTATGGTATT
GGACATAGATAAACTGTTTCACGTTAGACCTGTAACCCAAGGAGATGTGTATAGAGCTGAAACTGAAGAAATTCCTAAAATATTCCAGAT
ACTATATGCAAATGAAGGTGAATGTAGAAAAGATGTAGAGATGGAACCAGTACAACAAGCTGAAAAAACTAATTTCCAAAATCACAAAGG
CCATGAGTTTATTCCTACACTCTACCACTTTCCTGCCAATTGTGATGCCTGTGCCAAACCTCTCTGGCATGTTTTTAAGCCACCCCCTGC
CCTAGAGTGTCGAAGATGCCATGTTAAGTGCCACAGAGATCACTTAGATAAGAAAGAGGACTTAATTTGTCCATGTAAAGTAAGTTATGA
TGTAACATCAGCAAGAGATATGCTGCTGTTAGCATGTTCTCAGGATGAACAAAAAAAATGGGTAACTCATTTAGTAAAGAAAATCCCTAA
GAATCCACCATCTGGTTTTGTTCGTGCTTCCCCTCGAACGCTTTCTACAAGATCCACTGCAAATCAGTCTTTCCGGAAAGTGGTCAAAAA
TACATCTGGAAAAACTAGTTAACCATGTGACTGAGTGCCCTGTGGAATCGTGTGGGATGCTACCTGATAAACCAGGCTTCTTTAACCATG
CAGAGCAGACAGGCTGTTTCTTTGACACAAATATCACAGGCTTCAGGGTTAAGATTGCTGTTTTTCTGTCCTTGCTTTGGCACAACACAC
TGAGGGTTTTTTTTATTGCGGGTTTGCCTACAGGTAGATTAGATTAATTATTACTATGTAATGCAAGTACAGTTGGGGGAAAGCTTAGGT
AGATATATTTTTTTTAAAAGGTGCTGCCTTTTTGGATTTATAAGAAAATGCCTGTCAGTCGTGATAGAACAGAGTTTTCCTCATATGAGT
AAGAGGAAGGGACTTTCACTTTCAAGTGGAACAGCCATCACTATCAAGATCAGCTCATGGAAGGAGTAAAGAAAATATCTCAAAATGAGA
CAAACTGAAGTTTTGTTTTTTTTTTAATGACTTAAGTTTTTGTGCTCTTGCAAGACTATACAAAACTATTTTAAGAAAGCAGTGATATCA
CTTGAACTTCAGTGCCCTCACTGTAGAATTTAAAAGCCTTACTGTTGATTGCCCATGTTGGACTTGATGGAGAAATTAAATATCTTTCAT
TATGCTTTACAAAATACTGTATATGTTTCAGCAAGTTTGGGGAATGGGAGAGGACAAAAAAAAGTTACATTTAATCTATGCATTTTTGCC
AAGCCATATTGAGTTATTTTACTACTAGAGACATTAGGAAACTAACTGTACAAAAGAACCAAGTTTAAAAGCATTTTGTGGGGTACATCA
TTTCTATAATTGTATAATGTATTTCTTTGTGGTTTTAAATGATAAAGACATTAAGTTAACAAACATATAAGAAATGTATGCACTGTTTGA
AATGTAAATTATTCTTAGAACACTTTCAATGGGGGTTGCATTGTCCTTTTAGTGCCTTAATTTGAGATAATTATTTTACTGCCATGAGTA
AGTATAGAAATTTCAAAAAATGTATTTTCAAAAAATTATGTGTGTCAGTGAGTTTTTCATTGATAATTGGTTTAATTTAAAATATTTAGA
GGTTTGTTGGACTTTCATAAATTGAGTACAATCTTTGCATCAAACTACCTGCTACAATAATGACTTTATAAAACTGCAAAAAATGTAGAA
GGTTGCACCAACATAAAAAGGAAATATGGCAATACATCCATGATGTTTTCCAGTTAACATAGGAATTACCAGATAAATACTGTTAAACTC
TTGTCCAGTAACAAGAGTTGATTCATATGGACAGTATGATTTATTGTTTATTTTTTTAACCAAATACCTCCTCAGTAATTTATAATGGCT
TTGCAGTAATGTGTATCAGATAAGAAGCACTGGAAAACCGATCGTCTCTAGGATGATATGCATGTTTCAAGTGGTATTGAAAGCCGCACT
GATGGATATGTAATAATAAACATATCTGTTATTAATATACTAATGACTCTGTGCTCATTTAATGAGAAATAAAAGTAATTTATGGATGGG
TATCTTTAATTTTTACTGCAATGTGTTTTCTCATGGCTGAAATGAATGGAAAACATACTTCAAATTAGTCTCTGATTGTATATAAATGTT
TGTGAAATTCCATGGTTAGATTAAAGTGTATTTTTAAAAGATAAAACGTGGTCTTGGGCTCTAAAACAAGAGTGGGAATAGTTCACATGA
AAAGCTGGCTAAAGTGTGTTGGAAAACAATTCTCCATGGGTCTCTTGCATTTCTACACATCAGGGAAGCAGAGGCTCTGACAACCTTTCT
TTTGACTATCTTTTCCAAGGATATTTATGTAGTAAACAGCCTTGGAAGATAGAGTTCTCCCTTGTGAGGATGTCGGGTTCTTTTACTGTC
CAGTATAATAAAGATAACGTCTCCCACCTATGATGCAAACCCACTGTGTGCTCAGCACCCACCTGGGCCACTCTGCATTGCCCACATGGG
GCTTGGAGGGCAAAGGGAACTGATGGAACGTGAAACTTATGCTGCTTTTGCTGTGCTGTGAATGAAGTCATCTGACTCTGACCCAGGGGT
CTCATCTCTTTTGTCAGGATCCATGAAACTGTGACTGGCAGCATGCAAACAGGATAAAATCTCAGCACAGTTCCTGACGGTGTCCTTACT
ACCTTCTCAGACTCATCACCATTACCTAATATTTTAAGGTCCAGTTGCAGAGAACAGAGTTAATTCTAATTAGTTTAAGCAAGAGAAGAC
TTTCCAAATGACATACTAATCTGAACTTAGAATTGTTGAGAACTGAGAGAGCTTTGAGGAATCACTCCCAATGCCACATTACAGAACTGG
GTCAACCAGGAGAGCTGCTTCCTCTTCTAAGTTCAGGAAACCACTCACTCCCAAGTATACCAATATTGAGAGGGTCCAGATAGTGCCATA
ATCAGGAATCCACACTACCACTGCTGGTTCTCTGCAACACTTGTCAGGCTTGCTACAATCTACCTCCAGTTAGATGTTTTGTACCATTCC
TCTTGCCACTTAAGAACCTCATGTCTGCACACTGCCTCAGAAAAGGCACTTCCATGACCCTGCTTGCTGGCATTTAGCACAGCCTGCATC
TCACGTCTGCCTTCTCTAGGTGCATCTACGTGGCCAAAATTAAATCACATCCAGACCCCTAGCTGCAAGAAAGTCTGAGAAATATAGCCT
CTAGCTTTCTCTCTAATTTGTTACAGGAGGACACACTAGGAGTGTGGAATGAAGGTTCAGCATTGAGTTAGCCCATGCACCCACACCTGT
AAGCTTCTCTGAGATCAGGAACTCCAGCTTTGGGCAACAAAGAAAACATAGCCACTGTCATTATTCACAGGTTCACTCATGACCTGTCAT
TTGGGGTTTCAGCTTAAATTAACCCATTCACCCTTCATTTAAAGTAAAAAAAATAAGTAAAAGAACTTAAATGACAAACTCATAGTTACT
TGAGTTTGTAATTCATAGTTAACTTTCACAGTTCTATAATCAATCTGGAATTCAGAGTGAGGTAGAGATCAAGCAGTATTTCTCCCATAT
GGATATTCAGTTGATACTGCAGTATTCATTGAAAATACTTCTTTCCTGCATCGTAATTCAGGTGAACAATCCATTGGTGTTATTTCTGTG
TCCTTGCCAATATCACACTTTTAATTACTGTAACTTTATAATAAGATTTTATATCTGTAGTAGAAGTCCAACTTTGTAATCCCTCCCAAT
TGGCTTGGCTATTCTTGGCCTTTTGCATTTCCATATAATTTTTTATTTTTGTTTTGAAACGAAGTTTCGCTCTTGTTGCCCAGGCTGGAG
TGCAGTGGCGCGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATCCTCCTGCCTCAGACTCCCGAGTAGCTGGGATTACA
GGTGCCCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGCCTGGTCTTGAACTCCTGACC
TCAGGTGATCCACACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCTGGTTGCATTCCCATATAAATTTAA
AAACAATCTACTGAAAGATGTATACGACCTCCACCAAGAAAATTGTAAGACATTTGGAGAAGTTTAAAAAGACATGAATAAACGGAAATG
GTTTTTTTAAATAAACAAATGATTTTTAAAGTTGATCATTAGGTTAATAAATAGTCATATAATGACAATCCGATGAGATTATGTTGCCCA
GGGTGGTCTCTAACTCCTAGCCTCAAGCAGTTTTACTCTCTCATTACAGGTGTAGGCCACCGTGCCTGGCCTGACACTTGGAAATCTTAA
TCACAATTATTCTTTGTTTTTATAATGTTTACTGTTCAAATCAATTTCTGGTTGGATAGTATGTATATATAAAGCCATGCTCAATGGCCT
AGATATATTTACTGCCAAATCTTTTATGCTTTTAGTGTTTTTTTTCTGGACAAGATCTATGCTTATTGCAATAAATTAAATGCAAAGAAT
ATTCTAGTAGAAAGTCAGTCTGCACTTCCTAAACCCCACCCCACCCCACCAATTCCTTCATAACTGTTATTAACAGTTAGCTGTGTTTTC
TAATGGATTATCTCCAAAGTATATGTAACTCAGATTTTTGTGAGGTAGGAAAAGAATAACATTAATTCCACTTCACATATTGAAAGTCTA
ACATACAAAGAGATTAAATATCTCCTTTCTTTTGCCAAATGTTAATGAATTGTCTTATGAGAATTAAGATATGATACTTTCTCCCAAGCT
ATACTGTTTCCCATAAAGTATTTGAGATGTTGGAGATTCAAGGGAAAAAATATAAATGCTTAGAAATAAAGTGTATAATGCAAAGATTGT
GAATAAAGTGACACTTGTATGTTAATCCTATAAATTGGTTTCTTGTACCATGTAGGATGGTTTGGCTATTAAATTGAATTAAGTGGTTCA

>33729_33729_4_GNE-ROCK1_GNE_chr9_36236829_ENST00000447283_ROCK1_chr18_18650574_ENST00000399799_length(amino acids)=1326AA_BP=3
MTQDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDS
AFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDK
SGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLT
FPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIPKAFV
GNQLPFVGFTYYSNRRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLE
STVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSH
TEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDM
LNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDL
KQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQ
MRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNR
QEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKID
RKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKLLDLSDSTSVASFPS
ADETDGNLPESRIEGWLSVPNRGNIKRYGWKKQYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQI
LYANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCDACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLICPCKVSYD

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Fusion Gene PPI Analysis for GNE-ROCK1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneROCK1chr9:36236828chr18:18650574ENST00000399799033368_72731.01355.0FHOD1
TgeneROCK1chr9:36236829chr18:18650574ENST00000399799033368_72731.01355.0FHOD1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GNE-ROCK1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GNE-ROCK1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource