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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:GNPTAB-CNOT2 (FusionGDB2 ID:33821) |
Fusion Gene Summary for GNPTAB-CNOT2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GNPTAB-CNOT2 | Fusion gene ID: 33821 | Hgene | Tgene | Gene symbol | GNPTAB | CNOT2 | Gene ID | 79158 | 4848 |
| Gene name | N-acetylglucosamine-1-phosphate transferase subunits alpha and beta | CCR4-NOT transcription complex subunit 2 | |
| Synonyms | GNPTA|ICD | CDC36|HSPC131|IDNADFS|NOT2|NOT2H | |
| Cytomap | 12q23.2 | 12q15 | |
| Type of gene | protein-coding | protein-coding | |
| Description | N-acetylglucosamine-1-phosphotransferase subunits alpha/betaGlcNAc phosphotransferaseN-acetylglucosamine-1-phosphate transferase alpha and beta subunitsUDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/betaUDP-N-acetylglucosamine-lysosomal-e | CCR4-NOT transcription complex subunit 2CCR4-associated factor 2negative regulator of transcription 2 | |
| Modification date | 20200328 | 20200313 | |
| UniProtAcc | Q3T906 | Q9NZN8 | |
| Ensembl transtripts involved in fusion gene | ENST00000299314, ENST00000549940, ENST00000392919, ENST00000549165, | ENST00000548230, ENST00000551483, ENST00000229195, ENST00000418359, | |
| Fusion gene scores | * DoF score | 12 X 9 X 7=756 | 27 X 20 X 10=5400 |
| # samples | 12 | 29 | |
| ** MAII score | log2(12/756*10)=-2.65535182861255 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(29/5400*10)=-4.21883460192326 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: GNPTAB [Title/Abstract] AND CNOT2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | GNPTAB(102173930)-CNOT2(70704675), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | GNPTAB | GO:0046835 | carbohydrate phosphorylation | 19955174|23733939 |
| Tgene | CNOT2 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 14707134|16712523 |
| Fusion gene breakpoints across GNPTAB (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across CNOT2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BLCA | TCGA-GC-A3RD-01A | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
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Fusion Gene ORF analysis for GNPTAB-CNOT2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000299314 | ENST00000548230 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| 5CDS-intron | ENST00000299314 | ENST00000551483 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| 5CDS-intron | ENST00000549940 | ENST00000548230 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| 5CDS-intron | ENST00000549940 | ENST00000551483 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| In-frame | ENST00000299314 | ENST00000229195 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| In-frame | ENST00000299314 | ENST00000418359 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| In-frame | ENST00000549940 | ENST00000229195 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| In-frame | ENST00000549940 | ENST00000418359 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| intron-3CDS | ENST00000392919 | ENST00000229195 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| intron-3CDS | ENST00000392919 | ENST00000418359 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| intron-3CDS | ENST00000549165 | ENST00000229195 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| intron-3CDS | ENST00000549165 | ENST00000418359 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| intron-intron | ENST00000392919 | ENST00000548230 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| intron-intron | ENST00000392919 | ENST00000551483 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| intron-intron | ENST00000549165 | ENST00000548230 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| intron-intron | ENST00000549165 | ENST00000551483 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000299314 | GNPTAB | chr12 | 102173930 | - | ENST00000229195 | CNOT2 | chr12 | 70704675 | + | 3687 | 1034 | 155 | 2608 | 817 |
| ENST00000299314 | GNPTAB | chr12 | 102173930 | - | ENST00000418359 | CNOT2 | chr12 | 70704675 | + | 3687 | 1034 | 155 | 2608 | 817 |
| ENST00000549940 | GNPTAB | chr12 | 102173930 | - | ENST00000229195 | CNOT2 | chr12 | 70704675 | + | 3567 | 914 | 35 | 2488 | 817 |
| ENST00000549940 | GNPTAB | chr12 | 102173930 | - | ENST00000418359 | CNOT2 | chr12 | 70704675 | + | 3567 | 914 | 35 | 2488 | 817 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000299314 | ENST00000229195 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + | 0.001200261 | 0.9987997 |
| ENST00000299314 | ENST00000418359 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + | 0.001200261 | 0.9987997 |
| ENST00000549940 | ENST00000229195 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + | 0.001137548 | 0.9988625 |
| ENST00000549940 | ENST00000418359 | GNPTAB | chr12 | 102173930 | - | CNOT2 | chr12 | 70704675 | + | 0.001137548 | 0.9988625 |
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Fusion Genomic Features for GNPTAB-CNOT2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| GNPTAB | chr12 | 102173929 | - | CNOT2 | chr12 | 70704674 | + | 1.64E-05 | 0.99998355 |
| GNPTAB | chr12 | 102173929 | - | CNOT2 | chr12 | 70704674 | + | 1.64E-05 | 0.99998355 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for GNPTAB-CNOT2 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:102173930/chr12:70704675) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GNPTAB | CNOT2 |
| FUNCTION: Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. M6P residues are required to bind to the M6P receptors (MPR), which mediate the vesicular transport of lysosomal enzymes to the endosomal/prelysosomal compartment. {ECO:0000269|PubMed:19955174, ECO:0000269|PubMed:23733939, ECO:0000269|PubMed:28918368}. | FUNCTION: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specifically involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of embryonic stem (ES) cell identity. {ECO:0000269|PubMed:14707134, ECO:0000269|PubMed:16712523, ECO:0000269|PubMed:21299754, ECO:0000269|PubMed:22367759}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000299314 | - | 7 | 21 | 22_42 | 257 | 1257.0 | Transmembrane | Helical |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000549940 | - | 7 | 11 | 22_42 | 257 | 491.0 | Transmembrane | Helical |
| Tgene | CNOT2 | chr12:102173930 | chr12:70704675 | ENST00000229195 | 1 | 16 | 437_540 | 16 | 541.0 | Region | Note=Repressor domain | |
| Tgene | CNOT2 | chr12:102173930 | chr12:70704675 | ENST00000418359 | 2 | 17 | 437_540 | 16 | 541.0 | Region | Note=Repressor domain | |
| Tgene | CNOT2 | chr12:102173930 | chr12:70704675 | ENST00000551483 | 0 | 7 | 437_540 | 0 | 192.0 | Region | Note=Repressor domain |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000299314 | - | 7 | 21 | 1018_1029 | 257 | 1257.0 | Calcium binding | Ontology_term=ECO:0000255 |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000549940 | - | 7 | 11 | 1018_1029 | 257 | 491.0 | Calcium binding | Ontology_term=ECO:0000255 |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000299314 | - | 7 | 21 | 465_498 | 257 | 1257.0 | Compositional bias | Note=Gly-rich |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000549940 | - | 7 | 11 | 465_498 | 257 | 491.0 | Compositional bias | Note=Gly-rich |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000299314 | - | 7 | 21 | 1005_1040 | 257 | 1257.0 | Domain | EF-hand |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000299314 | - | 7 | 21 | 699_798 | 257 | 1257.0 | Domain | DMAP1-binding |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000549940 | - | 7 | 11 | 1005_1040 | 257 | 491.0 | Domain | EF-hand |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000549940 | - | 7 | 11 | 699_798 | 257 | 491.0 | Domain | DMAP1-binding |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000299314 | - | 7 | 21 | 438_473 | 257 | 1257.0 | Repeat | Note=LNR 1 |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000299314 | - | 7 | 21 | 505_545 | 257 | 1257.0 | Repeat | Note=LNR 2 |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000549940 | - | 7 | 11 | 438_473 | 257 | 491.0 | Repeat | Note=LNR 1 |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000549940 | - | 7 | 11 | 505_545 | 257 | 491.0 | Repeat | Note=LNR 2 |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000299314 | - | 7 | 21 | 1215_1235 | 257 | 1257.0 | Transmembrane | Helical |
| Hgene | GNPTAB | chr12:102173930 | chr12:70704675 | ENST00000549940 | - | 7 | 11 | 1215_1235 | 257 | 491.0 | Transmembrane | Helical |
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Fusion Gene Sequence for GNPTAB-CNOT2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >33821_33821_1_GNPTAB-CNOT2_GNPTAB_chr12_102173930_ENST00000299314_CNOT2_chr12_70704675_ENST00000229195_length(transcript)=3687nt_BP=1034nt AGACCCGGGCGGCGCCGGCCGCCTCGCCGGCCGCAGGTCCGCCTCCGCCGCGCCGAGGGCGTGGGCTCCCGGCTCCCGGAAGCGGCGGCC GCGGCGCGGAGCCGAGCGGGCGTCCGTCGCCGGAGCTGCAATGAGCGGCGCCCGGAGGCTGTGACCTGCGCGCGGCGGCCCGACCGGGGC CCCTGAATGGCGGCTCGCTGAGGCGGCGGCGGCGGCGGCGGCGGCTCAGGCTCCTCGGGGCGTGGCGTGGCGGTGAAGGGGTGATGCTGT TCAAGCTCCTGCAGAGACAGACCTATACCTGCCTGTCCCACAGGTATGGGCTCTACGTGTGCTTCTTGGGCGTCGTTGTCACCATCGTCT CCGCCTTCCAGTTCGGAGAGGTGGTTCTGGAATGGAGCCGAGATCAATACCATGTTTTGTTTGATTCCTATAGAGACAATATTGCTGGAA AGTCCTTTCAGAATCGGCTTTGTCTGCCCATGCCGATTGACGTTGTTTACACCTGGGTGAATGGCACAGATCTTGAACTACTGAAGGAAC TACAGCAGGTCAGAGAACAGATGGAGGAGGAGCAGAAAGCAATGAGAGAAATCCTTGGGAAAAACACAACGGAACCTACTAAGAAGAGTG AGAAGCAGTTAGAGTGTTTGCTAACACACTGCATTAAGGTGCCAATGCTTGTCCTGGACCCAGCCCTGCCAGCCAACATCACCCTGAAGG ACCTGCCATCTCTTTATCCTTCTTTTCATTCTGCCAGTGACATTTTCAATGTTGCAAAACCAAAAAACCCTTCTACCAATGTCTCAGTTG TTGTTTTTGACAGTACTAAGGATGTTGAAGATGCCCACTCTGGACTGCTTAAAGGAAATAGCAGACAGACAGTATGGAGGGGCTACTTGA CAACAGATAAAGAAGTCCCTGGATTAGTGCTAATGCAAGATTTGGCTTTCCTGAGTGGATTTCCACCAACATTCAAGGAAACAAATCAAC TAAAAACAAAATTGCCAGAAAATCTTTCCTCTAAAGTCAAACTGGTGACAAACAGCATGTTTGGTGCTTCAAGAAAGAAGTTTGTAGAGG GGGTCGACAGTGACTACCATGACGAAAACATGTACTACAGCCAGTCTTCTATGTTTCCACATCGGTCAGAAAAAGATATGCTGGCATCAC CATCTACATCAGGTCAGCTGTCTCAGTTTGGGGCAAGTTTATACGGGCAACAAAGTGCACTAGGCCTTCCAATGAGGGGGATGAGCAACA ATACCCCTCAGTTAAATCGCAGCTTATCACAAGGCACTCAGTTACCGAGCCACGTCACGCCAACAACAGGGGTACCAACAATGTCACTTC ACACGCCTCCATCTCCAAGCAGGGGTATTTTGCCTATGAATCCTAGGAATATGATGAACCACTCCCAGGTTGGTCAGGGCATTGGAATTC CTAGCAGGACAAATAGCATGAGCAGTTCAGGGTTAGGTAGCCCCAACAGAAGCTCGCCAAGCATAATATGTATGCCAAAGCAGCAGCCTT CTCGACAGCCTTTTACTGTGAACAGTATGTCTGGATTTGGAATGAACAGGAATCAGGCATTTGGAATGAATAACTCCTTATCAAGTAACA TTTTTAATGGAACAGACGGAAGTGAAAATGTGACAGGATTGGACCTTTCAGATTTCCCAGCATTAGCAGACCGAAACAGGAGGGAAGGAA GTGGTAACCCAACTCCATTAATAAACCCCTTGGCTGGAAGAGCTCCTTATGTTGGAATGGTAACAAAACCAGCAAATGAACAATCCCAGG ACTTCTCAATACACAATGAAGATTTTCCAGCATTACCAGGCTCCAGCTATAAAGATCCAACATCAAGTAATGATGACAGTAAATCTAATT TGAATACATCTGGCAAGACAACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACAACACAAAATAATAACCAGCAGA AAAAAGGGATCCAGGTGTTACCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAATTTGGAATGATTGGCCTGTTAA CATTTATCAGGGCAGCAGAGACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACATTAGGCCTCAATCTGAACTCTC CTGAAAATCTCTACCCCAAATTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGACTTCCATGTTCCATCTGAGTACT TAACGAACATTCACATTAGGGATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTCTTCTATCTCTATTACATGAATG GAGGAGACGTATTACAACTTTTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAAGAACGAGTATGGATTACCAGGG CACCAGGCATGGAGCCAACAATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGTCTTAACTGGAGGAAAGTAGCTA AGGAGTTCCATCTGGAATATGACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAACCCTGCTCAGCAAGCCTTCTAAA AAAAAAAAAAAAAAAAAAAAAAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAACATAACTGCAGAACTGATGTGGC TCAGGCACCCTGGTTTTAATTCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGGTCCTGCCTTACTAATTATGTGC TGCCCAACAACTAAATTTGTAATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATTTCCTTTTTTGCCAGCAGACAGA CTTGAGTCTGTAAAGACAAGCAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGAAAACCCCCAAAAGACTCAAGAA AATTAGACCACAAATTTTGCATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCATTTTTATGTGAAGATCCTTCTC GTATTTCATTTGGAAAGATGAGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAAGGCAGTTTCGCCAAGCTTAATG CAAGAATATCTGACTGTTTAGAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTTATTACTGAGCTTCATCTTTCCA GAATGAGCAAAACACTGTCCAGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTTTTGGACATCACATGAATAAAGG TATGTATGTACGAATGTGTATATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTACCTCATTTTTAGGAGGTGTGCA TGGATGCAATATATGAAAATGGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACTAAAAGGGCCAGATTTTCAGCAG CCAAGGACATCCATACCCAAGTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTGGCTGTTTGAACAGCAGCGTTTC >33821_33821_1_GNPTAB-CNOT2_GNPTAB_chr12_102173930_ENST00000299314_CNOT2_chr12_70704675_ENST00000229195_length(amino acids)=817AA_BP=293 MRAAARPGPLNGGSLRRRRRRRRLRLLGAWRGGEGVMLFKLLQRQTYTCLSHRYGLYVCFLGVVVTIVSAFQFGEVVLEWSRDQYHVLFD SYRDNIAGKSFQNRLCLPMPIDVVYTWVNGTDLELLKELQQVREQMEEEQKAMREILGKNTTEPTKKSEKQLECLLTHCIKVPMLVLDPA LPANITLKDLPSLYPSFHSASDIFNVAKPKNPSTNVSVVVFDSTKDVEDAHSGLLKGNSRQTVWRGYLTTDKEVPGLVLMQDLAFLSGFP PTFKETNQLKTKLPENLSSKVKLVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLASPSTSGQLSQFGASLYGQQSALG LPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMSLHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSI ICMPKQQPSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRREGSGNPTPLINPLAGRAPYVGMVT KPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKSNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTD QFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDL LFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNY -------------------------------------------------------------- >33821_33821_2_GNPTAB-CNOT2_GNPTAB_chr12_102173930_ENST00000299314_CNOT2_chr12_70704675_ENST00000418359_length(transcript)=3687nt_BP=1034nt AGACCCGGGCGGCGCCGGCCGCCTCGCCGGCCGCAGGTCCGCCTCCGCCGCGCCGAGGGCGTGGGCTCCCGGCTCCCGGAAGCGGCGGCC GCGGCGCGGAGCCGAGCGGGCGTCCGTCGCCGGAGCTGCAATGAGCGGCGCCCGGAGGCTGTGACCTGCGCGCGGCGGCCCGACCGGGGC CCCTGAATGGCGGCTCGCTGAGGCGGCGGCGGCGGCGGCGGCGGCTCAGGCTCCTCGGGGCGTGGCGTGGCGGTGAAGGGGTGATGCTGT TCAAGCTCCTGCAGAGACAGACCTATACCTGCCTGTCCCACAGGTATGGGCTCTACGTGTGCTTCTTGGGCGTCGTTGTCACCATCGTCT CCGCCTTCCAGTTCGGAGAGGTGGTTCTGGAATGGAGCCGAGATCAATACCATGTTTTGTTTGATTCCTATAGAGACAATATTGCTGGAA AGTCCTTTCAGAATCGGCTTTGTCTGCCCATGCCGATTGACGTTGTTTACACCTGGGTGAATGGCACAGATCTTGAACTACTGAAGGAAC TACAGCAGGTCAGAGAACAGATGGAGGAGGAGCAGAAAGCAATGAGAGAAATCCTTGGGAAAAACACAACGGAACCTACTAAGAAGAGTG AGAAGCAGTTAGAGTGTTTGCTAACACACTGCATTAAGGTGCCAATGCTTGTCCTGGACCCAGCCCTGCCAGCCAACATCACCCTGAAGG ACCTGCCATCTCTTTATCCTTCTTTTCATTCTGCCAGTGACATTTTCAATGTTGCAAAACCAAAAAACCCTTCTACCAATGTCTCAGTTG TTGTTTTTGACAGTACTAAGGATGTTGAAGATGCCCACTCTGGACTGCTTAAAGGAAATAGCAGACAGACAGTATGGAGGGGCTACTTGA CAACAGATAAAGAAGTCCCTGGATTAGTGCTAATGCAAGATTTGGCTTTCCTGAGTGGATTTCCACCAACATTCAAGGAAACAAATCAAC TAAAAACAAAATTGCCAGAAAATCTTTCCTCTAAAGTCAAACTGGTGACAAACAGCATGTTTGGTGCTTCAAGAAAGAAGTTTGTAGAGG GGGTCGACAGTGACTACCATGACGAAAACATGTACTACAGCCAGTCTTCTATGTTTCCACATCGGTCAGAAAAAGATATGCTGGCATCAC CATCTACATCAGGTCAGCTGTCTCAGTTTGGGGCAAGTTTATACGGGCAACAAAGTGCACTAGGCCTTCCAATGAGGGGGATGAGCAACA ATACCCCTCAGTTAAATCGCAGCTTATCACAAGGCACTCAGTTACCGAGCCACGTCACGCCAACAACAGGGGTACCAACAATGTCACTTC ACACGCCTCCATCTCCAAGCAGGGGTATTTTGCCTATGAATCCTAGGAATATGATGAACCACTCCCAGGTTGGTCAGGGCATTGGAATTC CTAGCAGGACAAATAGCATGAGCAGTTCAGGGTTAGGTAGCCCCAACAGAAGCTCGCCAAGCATAATATGTATGCCAAAGCAGCAGCCTT CTCGACAGCCTTTTACTGTGAACAGTATGTCTGGATTTGGAATGAACAGGAATCAGGCATTTGGAATGAATAACTCCTTATCAAGTAACA TTTTTAATGGAACAGACGGAAGTGAAAATGTGACAGGATTGGACCTTTCAGATTTCCCAGCATTAGCAGACCGAAACAGGAGGGAAGGAA GTGGTAACCCAACTCCATTAATAAACCCCTTGGCTGGAAGAGCTCCTTATGTTGGAATGGTAACAAAACCAGCAAATGAACAATCCCAGG ACTTCTCAATACACAATGAAGATTTTCCAGCATTACCAGGCTCCAGCTATAAAGATCCAACATCAAGTAATGATGACAGTAAATCTAATT TGAATACATCTGGCAAGACAACTTCAAGTACAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACAACACAAAATAATAACCAGCAGA AAAAAGGGATCCAGGTGTTACCTGATGGTCGGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAATTTGGAATGATTGGCCTGTTAA CATTTATCAGGGCAGCAGAGACAGACCCAGGAATGGTACATCTTGCATTAGGAAGTGACTTAACAACATTAGGCCTCAATCTGAACTCTC CTGAAAATCTCTACCCCAAATTTGCGTCACCCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGACTTCCATGTTCCATCTGAGTACT TAACGAACATTCACATTAGGGATAAGCTGGCTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTCTTCTATCTCTATTACATGAATG GAGGAGACGTATTACAACTTTTAGCTGCAGTGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAAGAACGAGTATGGATTACCAGGG CACCAGGCATGGAGCCAACAATGAAAACCAATACCTATGAGAGGGGAACATATTACTTCTTTGACTGTCTTAACTGGAGGAAAGTAGCTA AGGAGTTCCATCTGGAATATGACAAATTAGAAGAACGGCCTCACCTGCCATCCACCTTCAACTACAACCCTGCTCAGCAAGCCTTCTAAA AAAAAAAAAAAAAAAAAAAAAAGACTTCCCTTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAACATAACTGCAGAACTGATGTGGC TCAGGCACCCTGGTTTTAATTCCTTGAGGATCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGGTCCTGCCTTACTAATTATGTGC TGCCCAACAACTAAATTTGTAATTTGTTTTTCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATTTCCTTTTTTGCCAGCAGACAGA CTTGAGTCTGTAAAGACAAGCAAATACACTGACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGAAAACCCCCAAAAGACTCAAGAA AATTAGACCACAAATTTTGCATTGTTCATTGTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCATTTTTATGTGAAGATCCTTCTC GTATTTCATTTGGAAAGATGAGCAAGAGGTCTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAAGGCAGTTTCGCCAAGCTTAATG CAAGAATATCTGACTGTTTAGAAGAAAGATATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTTATTACTGAGCTTCATCTTTCCA GAATGAGCAAAACACTGTCCAGTCTTTGTTACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTTTTGGACATCACATGAATAAAGG TATGTATGTACGAATGTGTATATATTATATATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTACCTCATTTTTAGGAGGTGTGCA TGGATGCAATATATGAAAATGGGACATTCTGGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACTAAAAGGGCCAGATTTTCAGCAG CCAAGGACATCCATACCCAAGTGAATGTGATGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTGGCTGTTTGAACAGCAGCGTTTC >33821_33821_2_GNPTAB-CNOT2_GNPTAB_chr12_102173930_ENST00000299314_CNOT2_chr12_70704675_ENST00000418359_length(amino acids)=817AA_BP=293 MRAAARPGPLNGGSLRRRRRRRRLRLLGAWRGGEGVMLFKLLQRQTYTCLSHRYGLYVCFLGVVVTIVSAFQFGEVVLEWSRDQYHVLFD SYRDNIAGKSFQNRLCLPMPIDVVYTWVNGTDLELLKELQQVREQMEEEQKAMREILGKNTTEPTKKSEKQLECLLTHCIKVPMLVLDPA LPANITLKDLPSLYPSFHSASDIFNVAKPKNPSTNVSVVVFDSTKDVEDAHSGLLKGNSRQTVWRGYLTTDKEVPGLVLMQDLAFLSGFP PTFKETNQLKTKLPENLSSKVKLVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLASPSTSGQLSQFGASLYGQQSALG LPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMSLHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSI ICMPKQQPSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRREGSGNPTPLINPLAGRAPYVGMVT KPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKSNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTD QFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDL LFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNY -------------------------------------------------------------- >33821_33821_3_GNPTAB-CNOT2_GNPTAB_chr12_102173930_ENST00000549940_CNOT2_chr12_70704675_ENST00000229195_length(transcript)=3567nt_BP=914nt CGGAGCTGCAATGAGCGGCGCCCGGAGGCTGTGACCTGCGCGCGGCGGCCCGACCGGGGCCCCTGAATGGCGGCTCGCTGAGGCGGCGGC GGCGGCGGCGGCGGCTCAGGCTCCTCGGGGCGTGGCGTGGCGGTGAAGGGGTGATGCTGTTCAAGCTCCTGCAGAGACAGACCTATACCT GCCTGTCCCACAGGTATGGGCTCTACGTGTGCTTCTTGGGCGTCGTTGTCACCATCGTCTCCGCCTTCCAGTTCGGAGAGGTGGTTCTGG AATGGAGCCGAGATCAATACCATGTTTTGTTTGATTCCTATAGAGACAATATTGCTGGAAAGTCCTTTCAGAATCGGCTTTGTCTGCCCA TGCCGATTGACGTTGTTTACACCTGGGTGAATGGCACAGATCTTGAACTACTGAAGGAACTACAGCAGGTCAGAGAACAGATGGAGGAGG AGCAGAAAGCAATGAGAGAAATCCTTGGGAAAAACACAACGGAACCTACTAAGAAGAGTGAGAAGCAGTTAGAGTGTTTGCTAACACACT GCATTAAGGTGCCAATGCTTGTCCTGGACCCAGCCCTGCCAGCCAACATCACCCTGAAGGACCTGCCATCTCTTTATCCTTCTTTTCATT CTGCCAGTGACATTTTCAATGTTGCAAAACCAAAAAACCCTTCTACCAATGTCTCAGTTGTTGTTTTTGACAGTACTAAGGATGTTGAAG ATGCCCACTCTGGACTGCTTAAAGGAAATAGCAGACAGACAGTATGGAGGGGCTACTTGACAACAGATAAAGAAGTCCCTGGATTAGTGC TAATGCAAGATTTGGCTTTCCTGAGTGGATTTCCACCAACATTCAAGGAAACAAATCAACTAAAAACAAAATTGCCAGAAAATCTTTCCT CTAAAGTCAAACTGGTGACAAACAGCATGTTTGGTGCTTCAAGAAAGAAGTTTGTAGAGGGGGTCGACAGTGACTACCATGACGAAAACA TGTACTACAGCCAGTCTTCTATGTTTCCACATCGGTCAGAAAAAGATATGCTGGCATCACCATCTACATCAGGTCAGCTGTCTCAGTTTG GGGCAAGTTTATACGGGCAACAAAGTGCACTAGGCCTTCCAATGAGGGGGATGAGCAACAATACCCCTCAGTTAAATCGCAGCTTATCAC AAGGCACTCAGTTACCGAGCCACGTCACGCCAACAACAGGGGTACCAACAATGTCACTTCACACGCCTCCATCTCCAAGCAGGGGTATTT TGCCTATGAATCCTAGGAATATGATGAACCACTCCCAGGTTGGTCAGGGCATTGGAATTCCTAGCAGGACAAATAGCATGAGCAGTTCAG GGTTAGGTAGCCCCAACAGAAGCTCGCCAAGCATAATATGTATGCCAAAGCAGCAGCCTTCTCGACAGCCTTTTACTGTGAACAGTATGT CTGGATTTGGAATGAACAGGAATCAGGCATTTGGAATGAATAACTCCTTATCAAGTAACATTTTTAATGGAACAGACGGAAGTGAAAATG TGACAGGATTGGACCTTTCAGATTTCCCAGCATTAGCAGACCGAAACAGGAGGGAAGGAAGTGGTAACCCAACTCCATTAATAAACCCCT TGGCTGGAAGAGCTCCTTATGTTGGAATGGTAACAAAACCAGCAAATGAACAATCCCAGGACTTCTCAATACACAATGAAGATTTTCCAG CATTACCAGGCTCCAGCTATAAAGATCCAACATCAAGTAATGATGACAGTAAATCTAATTTGAATACATCTGGCAAGACAACTTCAAGTA CAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACAACACAAAATAATAACCAGCAGAAAAAAGGGATCCAGGTGTTACCTGATGGTC GGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAATTTGGAATGATTGGCCTGTTAACATTTATCAGGGCAGCAGAGACAGACCCAG GAATGGTACATCTTGCATTAGGAAGTGACTTAACAACATTAGGCCTCAATCTGAACTCTCCTGAAAATCTCTACCCCAAATTTGCGTCAC CCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGACTTCCATGTTCCATCTGAGTACTTAACGAACATTCACATTAGGGATAAGCTGG CTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTCTTCTATCTCTATTACATGAATGGAGGAGACGTATTACAACTTTTAGCTGCAG TGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAAGAACGAGTATGGATTACCAGGGCACCAGGCATGGAGCCAACAATGAAAACCA ATACCTATGAGAGGGGAACATATTACTTCTTTGACTGTCTTAACTGGAGGAAAGTAGCTAAGGAGTTCCATCTGGAATATGACAAATTAG AAGAACGGCCTCACCTGCCATCCACCTTCAACTACAACCCTGCTCAGCAAGCCTTCTAAAAAAAAAAAAAAAAAAAAAAAAAGACTTCCC TTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAACATAACTGCAGAACTGATGTGGCTCAGGCACCCTGGTTTTAATTCCTTGAGGA TCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGGTCCTGCCTTACTAATTATGTGCTGCCCAACAACTAAATTTGTAATTTGTTTT TCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATTTCCTTTTTTGCCAGCAGACAGACTTGAGTCTGTAAAGACAAGCAAATACACT GACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGAAAACCCCCAAAAGACTCAAGAAAATTAGACCACAAATTTTGCATTGTTCATT GTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCATTTTTATGTGAAGATCCTTCTCGTATTTCATTTGGAAAGATGAGCAAGAGGT CTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAAGGCAGTTTCGCCAAGCTTAATGCAAGAATATCTGACTGTTTAGAAGAAAGAT ATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTTATTACTGAGCTTCATCTTTCCAGAATGAGCAAAACACTGTCCAGTCTTTGTT ACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTTTTGGACATCACATGAATAAAGGTATGTATGTACGAATGTGTATATATTATAT ATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTACCTCATTTTTAGGAGGTGTGCATGGATGCAATATATGAAAATGGGACATTCT GGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACTAAAAGGGCCAGATTTTCAGCAGCCAAGGACATCCATACCCAAGTGAATGTGA TGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTGGCTGTTTGAACAGCAGCGTTTCATAGGAAGAGAAAAAAAGATCAATCTTGTA >33821_33821_3_GNPTAB-CNOT2_GNPTAB_chr12_102173930_ENST00000549940_CNOT2_chr12_70704675_ENST00000229195_length(amino acids)=817AA_BP=293 MRAAARPGPLNGGSLRRRRRRRRLRLLGAWRGGEGVMLFKLLQRQTYTCLSHRYGLYVCFLGVVVTIVSAFQFGEVVLEWSRDQYHVLFD SYRDNIAGKSFQNRLCLPMPIDVVYTWVNGTDLELLKELQQVREQMEEEQKAMREILGKNTTEPTKKSEKQLECLLTHCIKVPMLVLDPA LPANITLKDLPSLYPSFHSASDIFNVAKPKNPSTNVSVVVFDSTKDVEDAHSGLLKGNSRQTVWRGYLTTDKEVPGLVLMQDLAFLSGFP PTFKETNQLKTKLPENLSSKVKLVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLASPSTSGQLSQFGASLYGQQSALG LPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMSLHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSI ICMPKQQPSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRREGSGNPTPLINPLAGRAPYVGMVT KPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKSNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTD QFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDL LFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNY -------------------------------------------------------------- >33821_33821_4_GNPTAB-CNOT2_GNPTAB_chr12_102173930_ENST00000549940_CNOT2_chr12_70704675_ENST00000418359_length(transcript)=3567nt_BP=914nt CGGAGCTGCAATGAGCGGCGCCCGGAGGCTGTGACCTGCGCGCGGCGGCCCGACCGGGGCCCCTGAATGGCGGCTCGCTGAGGCGGCGGC GGCGGCGGCGGCGGCTCAGGCTCCTCGGGGCGTGGCGTGGCGGTGAAGGGGTGATGCTGTTCAAGCTCCTGCAGAGACAGACCTATACCT GCCTGTCCCACAGGTATGGGCTCTACGTGTGCTTCTTGGGCGTCGTTGTCACCATCGTCTCCGCCTTCCAGTTCGGAGAGGTGGTTCTGG AATGGAGCCGAGATCAATACCATGTTTTGTTTGATTCCTATAGAGACAATATTGCTGGAAAGTCCTTTCAGAATCGGCTTTGTCTGCCCA TGCCGATTGACGTTGTTTACACCTGGGTGAATGGCACAGATCTTGAACTACTGAAGGAACTACAGCAGGTCAGAGAACAGATGGAGGAGG AGCAGAAAGCAATGAGAGAAATCCTTGGGAAAAACACAACGGAACCTACTAAGAAGAGTGAGAAGCAGTTAGAGTGTTTGCTAACACACT GCATTAAGGTGCCAATGCTTGTCCTGGACCCAGCCCTGCCAGCCAACATCACCCTGAAGGACCTGCCATCTCTTTATCCTTCTTTTCATT CTGCCAGTGACATTTTCAATGTTGCAAAACCAAAAAACCCTTCTACCAATGTCTCAGTTGTTGTTTTTGACAGTACTAAGGATGTTGAAG ATGCCCACTCTGGACTGCTTAAAGGAAATAGCAGACAGACAGTATGGAGGGGCTACTTGACAACAGATAAAGAAGTCCCTGGATTAGTGC TAATGCAAGATTTGGCTTTCCTGAGTGGATTTCCACCAACATTCAAGGAAACAAATCAACTAAAAACAAAATTGCCAGAAAATCTTTCCT CTAAAGTCAAACTGGTGACAAACAGCATGTTTGGTGCTTCAAGAAAGAAGTTTGTAGAGGGGGTCGACAGTGACTACCATGACGAAAACA TGTACTACAGCCAGTCTTCTATGTTTCCACATCGGTCAGAAAAAGATATGCTGGCATCACCATCTACATCAGGTCAGCTGTCTCAGTTTG GGGCAAGTTTATACGGGCAACAAAGTGCACTAGGCCTTCCAATGAGGGGGATGAGCAACAATACCCCTCAGTTAAATCGCAGCTTATCAC AAGGCACTCAGTTACCGAGCCACGTCACGCCAACAACAGGGGTACCAACAATGTCACTTCACACGCCTCCATCTCCAAGCAGGGGTATTT TGCCTATGAATCCTAGGAATATGATGAACCACTCCCAGGTTGGTCAGGGCATTGGAATTCCTAGCAGGACAAATAGCATGAGCAGTTCAG GGTTAGGTAGCCCCAACAGAAGCTCGCCAAGCATAATATGTATGCCAAAGCAGCAGCCTTCTCGACAGCCTTTTACTGTGAACAGTATGT CTGGATTTGGAATGAACAGGAATCAGGCATTTGGAATGAATAACTCCTTATCAAGTAACATTTTTAATGGAACAGACGGAAGTGAAAATG TGACAGGATTGGACCTTTCAGATTTCCCAGCATTAGCAGACCGAAACAGGAGGGAAGGAAGTGGTAACCCAACTCCATTAATAAACCCCT TGGCTGGAAGAGCTCCTTATGTTGGAATGGTAACAAAACCAGCAAATGAACAATCCCAGGACTTCTCAATACACAATGAAGATTTTCCAG CATTACCAGGCTCCAGCTATAAAGATCCAACATCAAGTAATGATGACAGTAAATCTAATTTGAATACATCTGGCAAGACAACTTCAAGTA CAGATGGACCCAAATTCCCTGGAGATAAAAGTTCAACAACACAAAATAATAACCAGCAGAAAAAAGGGATCCAGGTGTTACCTGATGGTC GGGTTACTAACATTCCTCAAGGGATGGTGACGGACCAATTTGGAATGATTGGCCTGTTAACATTTATCAGGGCAGCAGAGACAGACCCAG GAATGGTACATCTTGCATTAGGAAGTGACTTAACAACATTAGGCCTCAATCTGAACTCTCCTGAAAATCTCTACCCCAAATTTGCGTCAC CCTGGGCATCTTCACCTTGTCGACCTCAAGACATAGACTTCCATGTTCCATCTGAGTACTTAACGAACATTCACATTAGGGATAAGCTGG CTGCAATAAAACTTGGCCGATATGGTGAAGACCTTCTCTTCTATCTCTATTACATGAATGGAGGAGACGTATTACAACTTTTAGCTGCAG TGGAGCTTTTTAACCGTGATTGGAGATACCACAAAGAAGAACGAGTATGGATTACCAGGGCACCAGGCATGGAGCCAACAATGAAAACCA ATACCTATGAGAGGGGAACATATTACTTCTTTGACTGTCTTAACTGGAGGAAAGTAGCTAAGGAGTTCCATCTGGAATATGACAAATTAG AAGAACGGCCTCACCTGCCATCCACCTTCAACTACAACCCTGCTCAGCAAGCCTTCTAAAAAAAAAAAAAAAAAAAAAAAAAGACTTCCC TTTTCTTGGGGTATGGCTGTCTCAGCACAATACTCAACATAACTGCAGAACTGATGTGGCTCAGGCACCCTGGTTTTAATTCCTTGAGGA TCTGGCAATTGGCTTACGCAAAAGGTCACCATTTGAGGTCCTGCCTTACTAATTATGTGCTGCCCAACAACTAAATTTGTAATTTGTTTT TCTCTAGTTTGAGCAGGGTCTGAATTTTTTCATTTATTTCCTTTTTTGCCAGCAGACAGACTTGAGTCTGTAAAGACAAGCAAATACACT GACAGAAGTTTACCATAGTTTCTAAAATGTAAAAAAGAAAACCCCCAAAAGACTCAAGAAAATTAGACCACAAATTTTGCATTGTTCATT GTAGCACTATTGGTAATAAAATAACAAATGTTTGTGCATTTTTATGTGAAGATCCTTCTCGTATTTCATTTGGAAAGATGAGCAAGAGGT CTGCTTCCTTCATTTTACTTCCCCTTCTGTTTTTGAAAGGCAGTTTCGCCAAGCTTAATGCAAGAATATCTGACTGTTTAGAAGAAAGAT ATTGCCACAATCTCTGGATGGTTTTCCAGGGTTGTGTTATTACTGAGCTTCATCTTTCCAGAATGAGCAAAACACTGTCCAGTCTTTGTT ACGATTTTGTAATAAATGTGTACATTTTTTTTAAATTTTTGGACATCACATGAATAAAGGTATGTATGTACGAATGTGTATATATTATAT ATATGACATCTATTTTGGAAAATGTTTGCCCTGCTGTACCTCATTTTTAGGAGGTGTGCATGGATGCAATATATGAAAATGGGACATTCT GGAACTGCTGGTCAGGGGACTTTGTCGCCCTGTGCACTAAAAGGGCCAGATTTTCAGCAGCCAAGGACATCCATACCCAAGTGAATGTGA TGGGACTTAAAAGAAGTGAACTGAGACAATTCACTCTGGCTGTTTGAACAGCAGCGTTTCATAGGAAGAGAAAAAAAGATCAATCTTGTA >33821_33821_4_GNPTAB-CNOT2_GNPTAB_chr12_102173930_ENST00000549940_CNOT2_chr12_70704675_ENST00000418359_length(amino acids)=817AA_BP=293 MRAAARPGPLNGGSLRRRRRRRRLRLLGAWRGGEGVMLFKLLQRQTYTCLSHRYGLYVCFLGVVVTIVSAFQFGEVVLEWSRDQYHVLFD SYRDNIAGKSFQNRLCLPMPIDVVYTWVNGTDLELLKELQQVREQMEEEQKAMREILGKNTTEPTKKSEKQLECLLTHCIKVPMLVLDPA LPANITLKDLPSLYPSFHSASDIFNVAKPKNPSTNVSVVVFDSTKDVEDAHSGLLKGNSRQTVWRGYLTTDKEVPGLVLMQDLAFLSGFP PTFKETNQLKTKLPENLSSKVKLVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLASPSTSGQLSQFGASLYGQQSALG LPMRGMSNNTPQLNRSLSQGTQLPSHVTPTTGVPTMSLHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSI ICMPKQQPSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTGLDLSDFPALADRNRREGSGNPTPLINPLAGRAPYVGMVT KPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKSNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKGIQVLPDGRVTNIPQGMVTD QFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDL LFYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEERPHLPSTFNY -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for GNPTAB-CNOT2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for GNPTAB-CNOT2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for GNPTAB-CNOT2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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