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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GOLIM4-SLC40A1 (FusionGDB2 ID:33955)

Fusion Gene Summary for GOLIM4-SLC40A1

check button Fusion gene summary
Fusion gene informationFusion gene name: GOLIM4-SLC40A1
Fusion gene ID: 33955
HgeneTgene
Gene symbol

GOLIM4

SLC40A1

Gene ID

27333

30061

Gene namegolgi integral membrane protein 4solute carrier family 40 member 1
SynonymsGIMPC|GOLPH4|GPP130|P138FPN1|HFE4|IREG1|MST079|MSTP079|MTP1|SLC11A3
Cytomap

3q26.2

2q32.2

Type of geneprotein-codingprotein-coding
DescriptionGolgi integral membrane protein 4130 kDa golgi-localized phosphoproteincis Golgi-localized calcium-binding proteingolgi integral membrane protein, cisgolgi phosphoprotein 4golgi phosphoprotein of 130 kDagolgi-localized phosphoprotein of 130 kDatypesolute carrier family 40 member 1iron regulated gene 1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3solute carrier family 40 (iron-regulated transporter), member 1
Modification date2020031320200313
UniProtAcc

O00461

.
Ensembl transtripts involved in fusion geneENST00000309027, ENST00000470487, 
ENST00000418714, ENST00000261024, 
Fusion gene scores* DoF score14 X 11 X 10=15404 X 3 X 3=36
# samples 185
** MAII scorelog2(18/1540*10)=-3.09686153925259
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(5/36*10)=0.473931188332412
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: GOLIM4 [Title/Abstract] AND SLC40A1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGOLIM4(167742314)-SLC40A1(190440046), # samples:2
GOLIM4(167742313)-SLC40A1(190440046), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across GOLIM4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLC40A1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CV-7261-01AGOLIM4chr3

167742314

-SLC40A1chr2

190440046

-
ChimerDB4HNSCTCGA-CV-7261GOLIM4chr3

167742313

-SLC40A1chr2

190440046

-


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Fusion Gene ORF analysis for GOLIM4-SLC40A1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000309027ENST00000418714GOLIM4chr3

167742314

-SLC40A1chr2

190440046

-
5CDS-5UTRENST00000309027ENST00000418714GOLIM4chr3

167742313

-SLC40A1chr2

190440046

-
5CDS-5UTRENST00000470487ENST00000418714GOLIM4chr3

167742314

-SLC40A1chr2

190440046

-
5CDS-5UTRENST00000470487ENST00000418714GOLIM4chr3

167742313

-SLC40A1chr2

190440046

-
In-frameENST00000309027ENST00000261024GOLIM4chr3

167742314

-SLC40A1chr2

190440046

-
In-frameENST00000309027ENST00000261024GOLIM4chr3

167742313

-SLC40A1chr2

190440046

-
In-frameENST00000470487ENST00000261024GOLIM4chr3

167742314

-SLC40A1chr2

190440046

-
In-frameENST00000470487ENST00000261024GOLIM4chr3

167742313

-SLC40A1chr2

190440046

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000470487GOLIM4chr3167742314-ENST00000261024SLC40A1chr2190440046-5454255067241541160
ENST00000309027GOLIM4chr3167742314-ENST00000261024SLC40A1chr2190440046-473918354134391132
ENST00000470487GOLIM4chr3167742313-ENST00000261024SLC40A1chr2190440046-5454255067241541160
ENST00000309027GOLIM4chr3167742313-ENST00000261024SLC40A1chr2190440046-473918354134391132

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000470487ENST00000261024GOLIM4chr3167742314-SLC40A1chr2190440046-0.0029277380.9970722
ENST00000309027ENST00000261024GOLIM4chr3167742314-SLC40A1chr2190440046-0.0013895680.9986104
ENST00000470487ENST00000261024GOLIM4chr3167742313-SLC40A1chr2190440046-0.0029277380.9970722
ENST00000309027ENST00000261024GOLIM4chr3167742313-SLC40A1chr2190440046-0.0013895680.9986104

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Fusion Genomic Features for GOLIM4-SLC40A1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GOLIM4-SLC40A1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:167742314/chr2:190440046)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GOLIM4

O00461

.
FUNCTION: Plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi. {ECO:0000269|PubMed:15331763}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGOLIM4chr3:167742313chr2:190440046ENST00000470487-141635_244620697.0Coiled coilOntology_term=ECO:0000255
HgeneGOLIM4chr3:167742314chr2:190440046ENST00000470487-141635_244620697.0Coiled coilOntology_term=ECO:0000255
HgeneGOLIM4chr3:167742313chr2:190440046ENST00000470487-1416404_513620697.0Compositional biasNote=Gln-rich
HgeneGOLIM4chr3:167742314chr2:190440046ENST00000470487-1416404_513620697.0Compositional biasNote=Gln-rich
HgeneGOLIM4chr3:167742313chr2:190440046ENST00000470487-1416176_248620697.0RegionNote=Golgi targeting
HgeneGOLIM4chr3:167742313chr2:190440046ENST00000470487-141638_107620697.0RegionNote=Golgi targeting
HgeneGOLIM4chr3:167742313chr2:190440046ENST00000470487-141680_175620697.0RegionNote=Endosome targeting
HgeneGOLIM4chr3:167742314chr2:190440046ENST00000470487-1416176_248620697.0RegionNote=Golgi targeting
HgeneGOLIM4chr3:167742314chr2:190440046ENST00000470487-141638_107620697.0RegionNote=Golgi targeting
HgeneGOLIM4chr3:167742314chr2:190440046ENST00000470487-141680_175620697.0RegionNote=Endosome targeting
HgeneGOLIM4chr3:167742313chr2:190440046ENST00000470487-14162_12620697.0Topological domainCytoplasmic
HgeneGOLIM4chr3:167742314chr2:190440046ENST00000470487-14162_12620697.0Topological domainCytoplasmic
HgeneGOLIM4chr3:167742313chr2:190440046ENST00000470487-141613_33620697.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneGOLIM4chr3:167742314chr2:190440046ENST00000470487-141613_33620697.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneSLC40A1chr3:167742313chr2:190440046ENST0000026102418125_14737572.0TransmembraneHelical
TgeneSLC40A1chr3:167742313chr2:190440046ENST0000026102418299_32137572.0TransmembraneHelical
TgeneSLC40A1chr3:167742313chr2:190440046ENST0000026102418341_36337572.0TransmembraneHelical
TgeneSLC40A1chr3:167742313chr2:190440046ENST0000026102418370_39237572.0TransmembraneHelical
TgeneSLC40A1chr3:167742313chr2:190440046ENST0000026102418450_47237572.0TransmembraneHelical
TgeneSLC40A1chr3:167742313chr2:190440046ENST0000026102418492_51437572.0TransmembraneHelical
TgeneSLC40A1chr3:167742313chr2:190440046ENST0000026102418519_54137572.0TransmembraneHelical
TgeneSLC40A1chr3:167742313chr2:190440046ENST000002610241858_8037572.0TransmembraneHelical
TgeneSLC40A1chr3:167742313chr2:190440046ENST000002610241893_11537572.0TransmembraneHelical
TgeneSLC40A1chr3:167742314chr2:190440046ENST0000026102418125_14737572.0TransmembraneHelical
TgeneSLC40A1chr3:167742314chr2:190440046ENST0000026102418299_32137572.0TransmembraneHelical
TgeneSLC40A1chr3:167742314chr2:190440046ENST0000026102418341_36337572.0TransmembraneHelical
TgeneSLC40A1chr3:167742314chr2:190440046ENST0000026102418370_39237572.0TransmembraneHelical
TgeneSLC40A1chr3:167742314chr2:190440046ENST0000026102418450_47237572.0TransmembraneHelical
TgeneSLC40A1chr3:167742314chr2:190440046ENST0000026102418492_51437572.0TransmembraneHelical
TgeneSLC40A1chr3:167742314chr2:190440046ENST0000026102418519_54137572.0TransmembraneHelical
TgeneSLC40A1chr3:167742314chr2:190440046ENST000002610241858_8037572.0TransmembraneHelical
TgeneSLC40A1chr3:167742314chr2:190440046ENST000002610241893_11537572.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGOLIM4chr3:167742313chr2:190440046ENST00000470487-1416311_681620697.0Compositional biasNote=Glu-rich
HgeneGOLIM4chr3:167742314chr2:190440046ENST00000470487-1416311_681620697.0Compositional biasNote=Glu-rich
HgeneGOLIM4chr3:167742313chr2:190440046ENST00000470487-141634_696620697.0Topological domainLumenal
HgeneGOLIM4chr3:167742314chr2:190440046ENST00000470487-141634_696620697.0Topological domainLumenal
TgeneSLC40A1chr3:167742313chr2:190440046ENST000002610241812_3437572.0TransmembraneHelical
TgeneSLC40A1chr3:167742314chr2:190440046ENST000002610241812_3437572.0TransmembraneHelical


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Fusion Gene Sequence for GOLIM4-SLC40A1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>33955_33955_1_GOLIM4-SLC40A1_GOLIM4_chr3_167742313_ENST00000309027_SLC40A1_chr2_190440046_ENST00000261024_length(transcript)=4739nt_BP=1835nt
GCTCGGACCAAGGGGAGGAGACGGCGGGGGCGGCCGCGGCTTTGGGTCCAGGCGGGACTATGGGAAACGGGATGTGCTCCCGAAAGCAGA
AGCGGATTTTCCAGACGCTGCTGCTGCTGACCGTCGTGTTCGGCTTTCTCTACGGCGCGATGCTCTACTACGAGCTGCAGACGCAGCTGC
GGAAAGCCGAGGCGGTGGCGCTCAAGTACCAGCAGCACCAGGAGTCCCTCTCCGCCCAGTTACAAGTTGTATATGAACACAGATCAAGAT
TAGAGAAATCCTTGCAAAAAGAAAGACTTGAACATAAAAAAGCAAAGGAAGATTTTCTTGTTTATAAGTTAGAAGCACAAGAAACATTAA
ATAAAGGAAGGCAAGATTCCAATAGCAGATACAGTGCACTGAATGTCCAACATCAGATGTTGAAAAGCCAACACGAGGAGCTAAAGAAAC
AGCACAGTGACTTGGAAGAGGAACATCGCAAACAAGGGGAAGACTTCAGTAGAACATTTAATGACCATAAGCAAAAATACTTGCAGCTCC
AGCAAGAAAAAGAACAAGAACTTTCTAAGCTAAAAGAGACTGTATACAATTTGAGAGAAGAGAATAGACAACTAAGGAAAGCACACCAAG
ACATACATACACAGCTTCAAGATGTCAAGACTCAAGTTGCAGAATATAAACAACTGAAAGATACTCTGAATAGGATTCCAAGCCTTCGAA
AACCTGATCCAGCAGAACAGCAAAATGTGACCCAGGTGGCACATTCTCCACAAGGTTACAACACAGCAAGGGAGAAGCCAACCCGAGAGG
TGCAGGAGGTGTCTCGAAATAATGATGTGTGGCAGAACCATGAAGCAGTTCCTGGAAGAGCAGAAGACACAAAACTCTATGCTCCCACCC
ATAAGGAGGCAGAATTTCAGGCTCCCCCAGAGCCAATCCAACAAGAAGTGGAACGCAGAGAACCTGAGGAGCATCAGGTGGAAGAGGAGC
ACAGAAAGGCCCTGGAGGAGGAAGAAATGGAGCAGGTCGGGCAAGCAGAACATCTTGAGGAGGAACACGATCCATCACCAGAGGAGCAGG
ATCGGGAGTGGAAAGAGCAGCATGAGCAACGAGAAGCAGCCAACCTCCTGGAAGGGCACGCGCGTGCTGAGGTGTACCCTTCAGCCAAGC
CAATGATCAAATTCCAATCACCCTATGAGGAACAGTTGGAACAGCAGAGACTGGCAGTGCAGCAGGTGGAGGAGGCCCAGCAGCTGCGGG
AACACCAGGAAGCTTTGCACCAGCAGAGGCTGCAGGGGCACTTACTACGGCAGCAGGAACAGCAGCAGCAGCAGGTGGCAAGAGAGATGG
CCCTGCAGAGGCAGGCTGAGCTTGAGGAGGGCCGGCCGCAGCACCAGGAGCAGCTCCGGCAGCAAGCTCATTATGATGCTATGGATAATG
ATATCGTTCAGGGAGCAGAGGACCAGGGAATCCAAGGAGAGGAAGGAGCCTATGAAAGAGACAACCAGCACCAAGATGAAGCAGAAGGAG
ATCCAGGTAATAGACATGAGCCTCGTGAACAAGGACCCCGAGAAGCCGACCCAGAATCTGAGGCAGATAGGGCAGCTGTAGAAGATATAA
ACCCAGCAGATGACCCTAATAATCAAGGTGAGGATGAATTTGAAGAAGCCGAGCAAGTGAGAGAAGAAAATTTGCCAGATGAAAATGAAG
AGCAAAAACAAAGTAATCAAAAGCAAGAGAATACAGAAGTGGAGGAACATTTGGTGATGGCAGGAAATCCAGACCAGCAGGAGGACAATG
TTGATGAACAGTACCAGGAAGAGGCAGAAGAGGAGGGAGATCGGATGTGGCACTTTGCGGTGTCTGTGTTTCTGGTAGAGCTCTATGGAA
ACAGCCTCCTTTTGACAGCAGTCTACGGGCTGGTGGTGGCAGGGTCTGTTCTGGTCCTGGGAGCCATCATCGGTGACTGGGTGGACAAGA
ATGCTAGACTTAAAGTGGCCCAGACCTCGCTGGTGGTACAGAATGTTTCAGTCATCCTGTGTGGAATCATCCTGATGATGGTTTTCTTAC
ATAAACATGAGCTTCTGACCATGTACCATGGATGGGTTCTCACTTCCTGCTATATCCTGATCATCACTATTGCAAATATTGCAAATTTGG
CCAGTACTGCTACTGCAATCACAATCCAAAGGGATTGGATTGTTGTTGTTGCAGGAGAAGACAGAAGCAAACTAGCAAATATGAATGCCA
CAATACGAAGGATTGACCAGTTAACCAACATCTTAGCCCCCATGGCTGTTGGCCAGATTATGACATTTGGCTCCCCAGTCATCGGCTGTG
GCTTTATTTCGGGATGGAACTTGGTATCCATGTGCGTGGAGTACGTTCTGCTCTGGAAGGTTTACCAGAAAACCCCAGCTCTAGCTGTGA
AAGCTGGTCTTAAAGAAGAGGAAACTGAATTGAAACAGCTGAATTTACACAAAGATACTGAGCCAAAACCCCTGGAGGGAACTCATCTAA
TGGGTGTGAAAGACTCTAACATCCATGAGCTTGAACATGAGCAAGAGCCTACTTGTGCCTCCCAGATGGCTGAGCCCTTCCGTACCTTCC
GAGATGGATGGGTCTCCTACTACAACCAGCCTGTGTTTCTGGCTGGCATGGGTCTTGCTTTCCTTTATATGACTGTCCTGGGCTTTGACT
GCATCACCACAGGGTACGCCTACACTCAGGGACTGAGTGGTTCCATCCTCAGTATTTTGATGGGAGCATCAGCTATAACTGGAATAATGG
GAACTGTAGCTTTTACTTGGCTACGTCGAAAATGTGGTTTGGTTCGGACAGGTCTGATCTCAGGATTGGCACAGCTTTCCTGTTTGATCT
TGTGTGTGATCTCTGTATTCATGCCTGGAAGCCCCCTGGACTTGTCCGTTTCTCCTTTTGAAGATATCCGATCAAGGTTCATTCAAGGAG
AGTCAATTACACCTACCAAGATACCTGAAATTACAACTGAAATATACATGTCTAATGGGTCTAATTCTGCTAATATTGTCCCGGAGACAA
GTCCTGAATCTGTGCCCATAATCTCTGTCAGTCTGCTGTTTGCAGGCGTCATTGCTGCTAGAATCGGTCTTTGGTCCTTTGATTTAACTG
TGACACAGTTGCTGCAAGAAAATGTAATTGAATCTGAAAGAGGCATTATAAATGGTGTACAGAACTCCATGAACTATCTTCTTGATCTTC
TGCATTTCATCATGGTCATCCTGGCTCCAAATCCTGAAGCTTTTGGCTTGCTCGTATTGATTTCAGTCTCCTTTGTGGCAATGGGCCACA
TTATGTATTTCCGATTTGCCCAAAATACTCTGGGAAACAAGCTCTTTGCTTGCGGTCCTGATGCAAAAGAAGTTAGGAAGGAAAATCAAG
CAAATACATCTGTTGTTTGAGACAGTTTAACTGTTGCTATCCTGTTACTAGATTATATAGAGCACATGTGCTTATTTTGTACTGCAGAAT
TCCAATAAATGGCTGGGTGTTTTGCTCTGTTTTTACCACAGCTGTGCCTTGAGAACTAAAAGCTGTTTAGGAAACCTAAGTCAGCAGAAA
TTAACTGATTAATTTCCCTTATGTTGAGGCATGGAAAAAAAATTGGAAAAGAAAAACTCAGTTTAAATACGGAGACTATAATGATAACAC
TGAATTCCCCTATTTCTCATGAGTAGATACAATCTTACGTAAAAGAGTGGTTAGTCACGTGAATTCAGTTATCATTTGACAGATTCTTAT
CTGTACTAGAATTCAGATATGTCAGTTTTCTGCAAAACTCACTCTTGTTCAAGACTAGCTAATTTATTTTTTTGCATCTTAGTTATTTTT
AAAAACAAATTCTTCAAGTATGAAGACTAAATTTTGATAACTAATATTATCCTTATTGATCCTATTGATCTTAAGGTATTTACATGTATG
TGGAAAAACAAAACACTTAACTAGAATTCTCTAATAAGGTTTATGGTTTAGCTTAAAGAGCACCTTTGTATTTTTATTATCAGATGGGGC
AACATATTGTATGAAGCATATGTAGCACTTCACAGCATGGTTATCATGTAAGCTGCAGGTAGAAGCAAAGCTGTAAAGTAGATTTATCAC
ACAATGACTGCATACAGACTTCAAATATGTCAATAGTTTGGTCATAGAACCTAGAAGCCAAAAGCCACACAGAAGGGCAAGAATCCCAAT
TTAACTCATGTTATCATCATTAGTGATCTGTGTTGTAGAACATGAGGGTGTAAGCCTTCAGCCTGGCAAGTTACATGTAGAAAGCCCACA
CTTGTGAAGGTTTTGTTTTACAAATCACTTGATTTAACACACTCAGGTAGAATATTTTTATTTTTACTGTTTTATACCCAGAAGTTATTT
CTACATTGTTCTACAGCAAGAATATTCATAAAAGTATCCCTTTCAAATGCCTTTGAGAAGAATAGAAGAAAAAAAGTTTGTATATATTTT
AAAAAATTGTTTTAAAAGTCAGTTTGCAACATGTCTGTACCAAGATGGTACTTTGCCTTAACCGTTTATATGCACTTTCATGGAGACTGC
AATACGTTGCTATGAGCACTTTCTTTATCCTTGGAGTTTAATCCTTTGCTTCATCTTTCTACAGTATGACATAATGATTTGCTATGTTGT

>33955_33955_1_GOLIM4-SLC40A1_GOLIM4_chr3_167742313_ENST00000309027_SLC40A1_chr2_190440046_ENST00000261024_length(amino acids)=1132AA_BP=598
MGPGGTMGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQLQVVYEHRSRLEKSLQKERLEHKK
AKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKET
VYNLREENRQLRKAHQDIHTQLQDVKTQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNH
EAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAA
NLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQ
HQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEF
EEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVA
GSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWI
VVVAGEDRSKLANMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLKEEETELKQL
NLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSG
SILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITPTKIPEITTE
IYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEA

--------------------------------------------------------------
>33955_33955_2_GOLIM4-SLC40A1_GOLIM4_chr3_167742313_ENST00000470487_SLC40A1_chr2_190440046_ENST00000261024_length(transcript)=5454nt_BP=2550nt
AATGAGCAAGGAGGCCGAGTGGGACTTCCTCCCGGAATCCCGTTGGCCAGAATAGCCGGGCCGTGGGTGACACGTAAGTTGGGCAGGAGG
TGGCGGGGCGGCAGAGGCACCAGCCGACCCGTCAGTGACACCGCTGTGCCGTCCCCAAAACCAGCCGAGACAGCTGGCCCCCACCCTTCC
ACCCATTGGGCAGGCCGCACGGGGGCGCGGCCCGGAGTCCTGGTCCCTTTGTTGGGCGCGCACCCCCTCCCTTAGGTGGCAACAAAGTCG
TGCAGTGGGAGCCGCCGCGATAGGGCGGGGAGTGGCCAGGGCGGGACTCCAAGAACTGCCCGGGGGCAGCGGGGCCAAAAAGTGGGAAGA
AGGAAAAAAGGCAGGAGGCATCTGGGGACAGGCGCGAGGGCAGCCGGCTCTGAAGTATGCGGAGGGCCTCCTCCCGGCCCCGGGCATTCG
CGGAGAACGAGCCTCGCAGAAGTTTGGCTGCAGCTGCCCGGGCGGCGTCGATGGCTGCGCGCCCCGCGCCGCGCGGGGGCTGAGCGGGCG
CCACTTCCCCTCCGGGCCGGCTTTTGTGTCTGGCATCTCCTCCTCATGCTGCGTCTGGCCACCTACTGCGGCGGCCGCTGCTGAGACGCT
CGCTCGGACCAAGGGGAGGAGACGGCGGGGGCGGCCGCGGCTTTGGGTCCAGGCGGGACTATGGGAAACGGGATGTGCTCCCGAAAGCAG
AAGCGGATTTTCCAGACGCTGCTGCTGCTGACCGTCGTGTTCGGCTTTCTCTACGGCGCGATGCTCTACTACGAGCTGCAGACGCAGCTG
CGGAAAGCCGAGGCGGTGGCGCTCAAGTACCAGCAGCACCAGGAGTCCCTCTCCGCCCAGTTACAAGTTGTATATGAACACAGATCAAGA
TTAGAGAAATCCTTGCAAAAAGAAAGACTTGAACATAAAAAAGCAAAGGAAGATTTTCTTGTTTATAAGTTAGAAGCACAAGAAACATTA
AATAAAGGAAGGCAAGATTCCAATAGCAGATACAGTGCACTGAATGTCCAACATCAGATGTTGAAAAGCCAACACGAGGAGCTAAAGAAA
CAGCACAGTGACTTGGAAGAGGAACATCGCAAACAAGGGGAAGACTTCAGTAGAACATTTAATGACCATAAGCAAAAATACTTGCAGCTC
CAGCAAGAAAAAGAACAAGAACTTTCTAAGCTAAAAGAGACTGTATACAATTTGAGAGAAGAGAATAGACAACTAAGGAAAGCACACCAA
GACATACATACACAGCTTCAAGATGTCAAGCAACAGCATAAGAATTTACTCTCCGAGCATGAACAACTTGTAGTGACTTTGGAAGACCAC
AAGAGTGCACTAGCTGCTGCACAGACTCAAGTTGCAGAATATAAACAACTGAAAGATACTCTGAATAGGATTCCAAGCCTTCGAAAACCT
GATCCAGCAGAACAGCAAAATGTGACCCAGGTGGCACATTCTCCACAAGGTTACAACACAGCAAGGGAGAAGCCAACCCGAGAGGTGCAG
GAGGTGTCTCGAAATAATGATGTGTGGCAGAACCATGAAGCAGTTCCTGGAAGAGCAGAAGACACAAAACTCTATGCTCCCACCCATAAG
GAGGCAGAATTTCAGGCTCCCCCAGAGCCAATCCAACAAGAAGTGGAACGCAGAGAACCTGAGGAGCATCAGGTGGAAGAGGAGCACAGA
AAGGCCCTGGAGGAGGAAGAAATGGAGCAGGTCGGGCAAGCAGAACATCTTGAGGAGGAACACGATCCATCACCAGAGGAGCAGGATCGG
GAGTGGAAAGAGCAGCATGAGCAACGAGAAGCAGCCAACCTCCTGGAAGGGCACGCGCGTGCTGAGGTGTACCCTTCAGCCAAGCCAATG
ATCAAATTCCAATCACCCTATGAGGAACAGTTGGAACAGCAGAGACTGGCAGTGCAGCAGGTGGAGGAGGCCCAGCAGCTGCGGGAACAC
CAGGAAGCTTTGCACCAGCAGAGGCTGCAGGGGCACTTACTACGGCAGCAGGAACAGCAGCAGCAGCAGGTGGCAAGAGAGATGGCCCTG
CAGAGGCAGGCTGAGCTTGAGGAGGGCCGGCCGCAGCACCAGGAGCAGCTCCGGCAGCAAGCTCATTATGATGCTATGGATAATGATATC
GTTCAGGGAGCAGAGGACCAGGGAATCCAAGGAGAGGAAGGAGCCTATGAAAGAGACAACCAGCACCAAGATGAAGCAGAAGGAGATCCA
GGTAATAGACATGAGCCTCGTGAACAAGGACCCCGAGAAGCCGACCCAGAATCTGAGGCAGATAGGGCAGCTGTAGAAGATATAAACCCA
GCAGATGACCCTAATAATCAAGGTGAGGATGAATTTGAAGAAGCCGAGCAAGTGAGAGAAGAAAATTTGCCAGATGAAAATGAAGAGCAA
AAACAAAGTAATCAAAAGCAAGAGAATACAGAAGTGGAGGAACATTTGGTGATGGCAGGAAATCCAGACCAGCAGGAGGACAATGTTGAT
GAACAGTACCAGGAAGAGGCAGAAGAGGAGGGAGATCGGATGTGGCACTTTGCGGTGTCTGTGTTTCTGGTAGAGCTCTATGGAAACAGC
CTCCTTTTGACAGCAGTCTACGGGCTGGTGGTGGCAGGGTCTGTTCTGGTCCTGGGAGCCATCATCGGTGACTGGGTGGACAAGAATGCT
AGACTTAAAGTGGCCCAGACCTCGCTGGTGGTACAGAATGTTTCAGTCATCCTGTGTGGAATCATCCTGATGATGGTTTTCTTACATAAA
CATGAGCTTCTGACCATGTACCATGGATGGGTTCTCACTTCCTGCTATATCCTGATCATCACTATTGCAAATATTGCAAATTTGGCCAGT
ACTGCTACTGCAATCACAATCCAAAGGGATTGGATTGTTGTTGTTGCAGGAGAAGACAGAAGCAAACTAGCAAATATGAATGCCACAATA
CGAAGGATTGACCAGTTAACCAACATCTTAGCCCCCATGGCTGTTGGCCAGATTATGACATTTGGCTCCCCAGTCATCGGCTGTGGCTTT
ATTTCGGGATGGAACTTGGTATCCATGTGCGTGGAGTACGTTCTGCTCTGGAAGGTTTACCAGAAAACCCCAGCTCTAGCTGTGAAAGCT
GGTCTTAAAGAAGAGGAAACTGAATTGAAACAGCTGAATTTACACAAAGATACTGAGCCAAAACCCCTGGAGGGAACTCATCTAATGGGT
GTGAAAGACTCTAACATCCATGAGCTTGAACATGAGCAAGAGCCTACTTGTGCCTCCCAGATGGCTGAGCCCTTCCGTACCTTCCGAGAT
GGATGGGTCTCCTACTACAACCAGCCTGTGTTTCTGGCTGGCATGGGTCTTGCTTTCCTTTATATGACTGTCCTGGGCTTTGACTGCATC
ACCACAGGGTACGCCTACACTCAGGGACTGAGTGGTTCCATCCTCAGTATTTTGATGGGAGCATCAGCTATAACTGGAATAATGGGAACT
GTAGCTTTTACTTGGCTACGTCGAAAATGTGGTTTGGTTCGGACAGGTCTGATCTCAGGATTGGCACAGCTTTCCTGTTTGATCTTGTGT
GTGATCTCTGTATTCATGCCTGGAAGCCCCCTGGACTTGTCCGTTTCTCCTTTTGAAGATATCCGATCAAGGTTCATTCAAGGAGAGTCA
ATTACACCTACCAAGATACCTGAAATTACAACTGAAATATACATGTCTAATGGGTCTAATTCTGCTAATATTGTCCCGGAGACAAGTCCT
GAATCTGTGCCCATAATCTCTGTCAGTCTGCTGTTTGCAGGCGTCATTGCTGCTAGAATCGGTCTTTGGTCCTTTGATTTAACTGTGACA
CAGTTGCTGCAAGAAAATGTAATTGAATCTGAAAGAGGCATTATAAATGGTGTACAGAACTCCATGAACTATCTTCTTGATCTTCTGCAT
TTCATCATGGTCATCCTGGCTCCAAATCCTGAAGCTTTTGGCTTGCTCGTATTGATTTCAGTCTCCTTTGTGGCAATGGGCCACATTATG
TATTTCCGATTTGCCCAAAATACTCTGGGAAACAAGCTCTTTGCTTGCGGTCCTGATGCAAAAGAAGTTAGGAAGGAAAATCAAGCAAAT
ACATCTGTTGTTTGAGACAGTTTAACTGTTGCTATCCTGTTACTAGATTATATAGAGCACATGTGCTTATTTTGTACTGCAGAATTCCAA
TAAATGGCTGGGTGTTTTGCTCTGTTTTTACCACAGCTGTGCCTTGAGAACTAAAAGCTGTTTAGGAAACCTAAGTCAGCAGAAATTAAC
TGATTAATTTCCCTTATGTTGAGGCATGGAAAAAAAATTGGAAAAGAAAAACTCAGTTTAAATACGGAGACTATAATGATAACACTGAAT
TCCCCTATTTCTCATGAGTAGATACAATCTTACGTAAAAGAGTGGTTAGTCACGTGAATTCAGTTATCATTTGACAGATTCTTATCTGTA
CTAGAATTCAGATATGTCAGTTTTCTGCAAAACTCACTCTTGTTCAAGACTAGCTAATTTATTTTTTTGCATCTTAGTTATTTTTAAAAA
CAAATTCTTCAAGTATGAAGACTAAATTTTGATAACTAATATTATCCTTATTGATCCTATTGATCTTAAGGTATTTACATGTATGTGGAA
AAACAAAACACTTAACTAGAATTCTCTAATAAGGTTTATGGTTTAGCTTAAAGAGCACCTTTGTATTTTTATTATCAGATGGGGCAACAT
ATTGTATGAAGCATATGTAGCACTTCACAGCATGGTTATCATGTAAGCTGCAGGTAGAAGCAAAGCTGTAAAGTAGATTTATCACACAAT
GACTGCATACAGACTTCAAATATGTCAATAGTTTGGTCATAGAACCTAGAAGCCAAAAGCCACACAGAAGGGCAAGAATCCCAATTTAAC
TCATGTTATCATCATTAGTGATCTGTGTTGTAGAACATGAGGGTGTAAGCCTTCAGCCTGGCAAGTTACATGTAGAAAGCCCACACTTGT
GAAGGTTTTGTTTTACAAATCACTTGATTTAACACACTCAGGTAGAATATTTTTATTTTTACTGTTTTATACCCAGAAGTTATTTCTACA
TTGTTCTACAGCAAGAATATTCATAAAAGTATCCCTTTCAAATGCCTTTGAGAAGAATAGAAGAAAAAAAGTTTGTATATATTTTAAAAA
ATTGTTTTAAAAGTCAGTTTGCAACATGTCTGTACCAAGATGGTACTTTGCCTTAACCGTTTATATGCACTTTCATGGAGACTGCAATAC
GTTGCTATGAGCACTTTCTTTATCCTTGGAGTTTAATCCTTTGCTTCATCTTTCTACAGTATGACATAATGATTTGCTATGTTGTAAAAT

>33955_33955_2_GOLIM4-SLC40A1_GOLIM4_chr3_167742313_ENST00000470487_SLC40A1_chr2_190440046_ENST00000261024_length(amino acids)=1160AA_BP=626
MGPGGTMGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQLQVVYEHRSRLEKSLQKERLEHKK
AKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKET
VYNLREENRQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHS
PQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQA
EHLEEEHDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLL
RQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREA
DPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEGDRM
WHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLTS
CYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYV
LLWKVYQKTPALAVKAGLKEEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLAG
MGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLS
VSPFEDIRSRFIQGESITPTKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGI

--------------------------------------------------------------
>33955_33955_3_GOLIM4-SLC40A1_GOLIM4_chr3_167742314_ENST00000309027_SLC40A1_chr2_190440046_ENST00000261024_length(transcript)=4739nt_BP=1835nt
GCTCGGACCAAGGGGAGGAGACGGCGGGGGCGGCCGCGGCTTTGGGTCCAGGCGGGACTATGGGAAACGGGATGTGCTCCCGAAAGCAGA
AGCGGATTTTCCAGACGCTGCTGCTGCTGACCGTCGTGTTCGGCTTTCTCTACGGCGCGATGCTCTACTACGAGCTGCAGACGCAGCTGC
GGAAAGCCGAGGCGGTGGCGCTCAAGTACCAGCAGCACCAGGAGTCCCTCTCCGCCCAGTTACAAGTTGTATATGAACACAGATCAAGAT
TAGAGAAATCCTTGCAAAAAGAAAGACTTGAACATAAAAAAGCAAAGGAAGATTTTCTTGTTTATAAGTTAGAAGCACAAGAAACATTAA
ATAAAGGAAGGCAAGATTCCAATAGCAGATACAGTGCACTGAATGTCCAACATCAGATGTTGAAAAGCCAACACGAGGAGCTAAAGAAAC
AGCACAGTGACTTGGAAGAGGAACATCGCAAACAAGGGGAAGACTTCAGTAGAACATTTAATGACCATAAGCAAAAATACTTGCAGCTCC
AGCAAGAAAAAGAACAAGAACTTTCTAAGCTAAAAGAGACTGTATACAATTTGAGAGAAGAGAATAGACAACTAAGGAAAGCACACCAAG
ACATACATACACAGCTTCAAGATGTCAAGACTCAAGTTGCAGAATATAAACAACTGAAAGATACTCTGAATAGGATTCCAAGCCTTCGAA
AACCTGATCCAGCAGAACAGCAAAATGTGACCCAGGTGGCACATTCTCCACAAGGTTACAACACAGCAAGGGAGAAGCCAACCCGAGAGG
TGCAGGAGGTGTCTCGAAATAATGATGTGTGGCAGAACCATGAAGCAGTTCCTGGAAGAGCAGAAGACACAAAACTCTATGCTCCCACCC
ATAAGGAGGCAGAATTTCAGGCTCCCCCAGAGCCAATCCAACAAGAAGTGGAACGCAGAGAACCTGAGGAGCATCAGGTGGAAGAGGAGC
ACAGAAAGGCCCTGGAGGAGGAAGAAATGGAGCAGGTCGGGCAAGCAGAACATCTTGAGGAGGAACACGATCCATCACCAGAGGAGCAGG
ATCGGGAGTGGAAAGAGCAGCATGAGCAACGAGAAGCAGCCAACCTCCTGGAAGGGCACGCGCGTGCTGAGGTGTACCCTTCAGCCAAGC
CAATGATCAAATTCCAATCACCCTATGAGGAACAGTTGGAACAGCAGAGACTGGCAGTGCAGCAGGTGGAGGAGGCCCAGCAGCTGCGGG
AACACCAGGAAGCTTTGCACCAGCAGAGGCTGCAGGGGCACTTACTACGGCAGCAGGAACAGCAGCAGCAGCAGGTGGCAAGAGAGATGG
CCCTGCAGAGGCAGGCTGAGCTTGAGGAGGGCCGGCCGCAGCACCAGGAGCAGCTCCGGCAGCAAGCTCATTATGATGCTATGGATAATG
ATATCGTTCAGGGAGCAGAGGACCAGGGAATCCAAGGAGAGGAAGGAGCCTATGAAAGAGACAACCAGCACCAAGATGAAGCAGAAGGAG
ATCCAGGTAATAGACATGAGCCTCGTGAACAAGGACCCCGAGAAGCCGACCCAGAATCTGAGGCAGATAGGGCAGCTGTAGAAGATATAA
ACCCAGCAGATGACCCTAATAATCAAGGTGAGGATGAATTTGAAGAAGCCGAGCAAGTGAGAGAAGAAAATTTGCCAGATGAAAATGAAG
AGCAAAAACAAAGTAATCAAAAGCAAGAGAATACAGAAGTGGAGGAACATTTGGTGATGGCAGGAAATCCAGACCAGCAGGAGGACAATG
TTGATGAACAGTACCAGGAAGAGGCAGAAGAGGAGGGAGATCGGATGTGGCACTTTGCGGTGTCTGTGTTTCTGGTAGAGCTCTATGGAA
ACAGCCTCCTTTTGACAGCAGTCTACGGGCTGGTGGTGGCAGGGTCTGTTCTGGTCCTGGGAGCCATCATCGGTGACTGGGTGGACAAGA
ATGCTAGACTTAAAGTGGCCCAGACCTCGCTGGTGGTACAGAATGTTTCAGTCATCCTGTGTGGAATCATCCTGATGATGGTTTTCTTAC
ATAAACATGAGCTTCTGACCATGTACCATGGATGGGTTCTCACTTCCTGCTATATCCTGATCATCACTATTGCAAATATTGCAAATTTGG
CCAGTACTGCTACTGCAATCACAATCCAAAGGGATTGGATTGTTGTTGTTGCAGGAGAAGACAGAAGCAAACTAGCAAATATGAATGCCA
CAATACGAAGGATTGACCAGTTAACCAACATCTTAGCCCCCATGGCTGTTGGCCAGATTATGACATTTGGCTCCCCAGTCATCGGCTGTG
GCTTTATTTCGGGATGGAACTTGGTATCCATGTGCGTGGAGTACGTTCTGCTCTGGAAGGTTTACCAGAAAACCCCAGCTCTAGCTGTGA
AAGCTGGTCTTAAAGAAGAGGAAACTGAATTGAAACAGCTGAATTTACACAAAGATACTGAGCCAAAACCCCTGGAGGGAACTCATCTAA
TGGGTGTGAAAGACTCTAACATCCATGAGCTTGAACATGAGCAAGAGCCTACTTGTGCCTCCCAGATGGCTGAGCCCTTCCGTACCTTCC
GAGATGGATGGGTCTCCTACTACAACCAGCCTGTGTTTCTGGCTGGCATGGGTCTTGCTTTCCTTTATATGACTGTCCTGGGCTTTGACT
GCATCACCACAGGGTACGCCTACACTCAGGGACTGAGTGGTTCCATCCTCAGTATTTTGATGGGAGCATCAGCTATAACTGGAATAATGG
GAACTGTAGCTTTTACTTGGCTACGTCGAAAATGTGGTTTGGTTCGGACAGGTCTGATCTCAGGATTGGCACAGCTTTCCTGTTTGATCT
TGTGTGTGATCTCTGTATTCATGCCTGGAAGCCCCCTGGACTTGTCCGTTTCTCCTTTTGAAGATATCCGATCAAGGTTCATTCAAGGAG
AGTCAATTACACCTACCAAGATACCTGAAATTACAACTGAAATATACATGTCTAATGGGTCTAATTCTGCTAATATTGTCCCGGAGACAA
GTCCTGAATCTGTGCCCATAATCTCTGTCAGTCTGCTGTTTGCAGGCGTCATTGCTGCTAGAATCGGTCTTTGGTCCTTTGATTTAACTG
TGACACAGTTGCTGCAAGAAAATGTAATTGAATCTGAAAGAGGCATTATAAATGGTGTACAGAACTCCATGAACTATCTTCTTGATCTTC
TGCATTTCATCATGGTCATCCTGGCTCCAAATCCTGAAGCTTTTGGCTTGCTCGTATTGATTTCAGTCTCCTTTGTGGCAATGGGCCACA
TTATGTATTTCCGATTTGCCCAAAATACTCTGGGAAACAAGCTCTTTGCTTGCGGTCCTGATGCAAAAGAAGTTAGGAAGGAAAATCAAG
CAAATACATCTGTTGTTTGAGACAGTTTAACTGTTGCTATCCTGTTACTAGATTATATAGAGCACATGTGCTTATTTTGTACTGCAGAAT
TCCAATAAATGGCTGGGTGTTTTGCTCTGTTTTTACCACAGCTGTGCCTTGAGAACTAAAAGCTGTTTAGGAAACCTAAGTCAGCAGAAA
TTAACTGATTAATTTCCCTTATGTTGAGGCATGGAAAAAAAATTGGAAAAGAAAAACTCAGTTTAAATACGGAGACTATAATGATAACAC
TGAATTCCCCTATTTCTCATGAGTAGATACAATCTTACGTAAAAGAGTGGTTAGTCACGTGAATTCAGTTATCATTTGACAGATTCTTAT
CTGTACTAGAATTCAGATATGTCAGTTTTCTGCAAAACTCACTCTTGTTCAAGACTAGCTAATTTATTTTTTTGCATCTTAGTTATTTTT
AAAAACAAATTCTTCAAGTATGAAGACTAAATTTTGATAACTAATATTATCCTTATTGATCCTATTGATCTTAAGGTATTTACATGTATG
TGGAAAAACAAAACACTTAACTAGAATTCTCTAATAAGGTTTATGGTTTAGCTTAAAGAGCACCTTTGTATTTTTATTATCAGATGGGGC
AACATATTGTATGAAGCATATGTAGCACTTCACAGCATGGTTATCATGTAAGCTGCAGGTAGAAGCAAAGCTGTAAAGTAGATTTATCAC
ACAATGACTGCATACAGACTTCAAATATGTCAATAGTTTGGTCATAGAACCTAGAAGCCAAAAGCCACACAGAAGGGCAAGAATCCCAAT
TTAACTCATGTTATCATCATTAGTGATCTGTGTTGTAGAACATGAGGGTGTAAGCCTTCAGCCTGGCAAGTTACATGTAGAAAGCCCACA
CTTGTGAAGGTTTTGTTTTACAAATCACTTGATTTAACACACTCAGGTAGAATATTTTTATTTTTACTGTTTTATACCCAGAAGTTATTT
CTACATTGTTCTACAGCAAGAATATTCATAAAAGTATCCCTTTCAAATGCCTTTGAGAAGAATAGAAGAAAAAAAGTTTGTATATATTTT
AAAAAATTGTTTTAAAAGTCAGTTTGCAACATGTCTGTACCAAGATGGTACTTTGCCTTAACCGTTTATATGCACTTTCATGGAGACTGC
AATACGTTGCTATGAGCACTTTCTTTATCCTTGGAGTTTAATCCTTTGCTTCATCTTTCTACAGTATGACATAATGATTTGCTATGTTGT

>33955_33955_3_GOLIM4-SLC40A1_GOLIM4_chr3_167742314_ENST00000309027_SLC40A1_chr2_190440046_ENST00000261024_length(amino acids)=1132AA_BP=598
MGPGGTMGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQLQVVYEHRSRLEKSLQKERLEHKK
AKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKET
VYNLREENRQLRKAHQDIHTQLQDVKTQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNH
EAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAA
NLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQ
HQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEF
EEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVA
GSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWI
VVVAGEDRSKLANMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLKEEETELKQL
NLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSG
SILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITPTKIPEITTE
IYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEA

--------------------------------------------------------------
>33955_33955_4_GOLIM4-SLC40A1_GOLIM4_chr3_167742314_ENST00000470487_SLC40A1_chr2_190440046_ENST00000261024_length(transcript)=5454nt_BP=2550nt
AATGAGCAAGGAGGCCGAGTGGGACTTCCTCCCGGAATCCCGTTGGCCAGAATAGCCGGGCCGTGGGTGACACGTAAGTTGGGCAGGAGG
TGGCGGGGCGGCAGAGGCACCAGCCGACCCGTCAGTGACACCGCTGTGCCGTCCCCAAAACCAGCCGAGACAGCTGGCCCCCACCCTTCC
ACCCATTGGGCAGGCCGCACGGGGGCGCGGCCCGGAGTCCTGGTCCCTTTGTTGGGCGCGCACCCCCTCCCTTAGGTGGCAACAAAGTCG
TGCAGTGGGAGCCGCCGCGATAGGGCGGGGAGTGGCCAGGGCGGGACTCCAAGAACTGCCCGGGGGCAGCGGGGCCAAAAAGTGGGAAGA
AGGAAAAAAGGCAGGAGGCATCTGGGGACAGGCGCGAGGGCAGCCGGCTCTGAAGTATGCGGAGGGCCTCCTCCCGGCCCCGGGCATTCG
CGGAGAACGAGCCTCGCAGAAGTTTGGCTGCAGCTGCCCGGGCGGCGTCGATGGCTGCGCGCCCCGCGCCGCGCGGGGGCTGAGCGGGCG
CCACTTCCCCTCCGGGCCGGCTTTTGTGTCTGGCATCTCCTCCTCATGCTGCGTCTGGCCACCTACTGCGGCGGCCGCTGCTGAGACGCT
CGCTCGGACCAAGGGGAGGAGACGGCGGGGGCGGCCGCGGCTTTGGGTCCAGGCGGGACTATGGGAAACGGGATGTGCTCCCGAAAGCAG
AAGCGGATTTTCCAGACGCTGCTGCTGCTGACCGTCGTGTTCGGCTTTCTCTACGGCGCGATGCTCTACTACGAGCTGCAGACGCAGCTG
CGGAAAGCCGAGGCGGTGGCGCTCAAGTACCAGCAGCACCAGGAGTCCCTCTCCGCCCAGTTACAAGTTGTATATGAACACAGATCAAGA
TTAGAGAAATCCTTGCAAAAAGAAAGACTTGAACATAAAAAAGCAAAGGAAGATTTTCTTGTTTATAAGTTAGAAGCACAAGAAACATTA
AATAAAGGAAGGCAAGATTCCAATAGCAGATACAGTGCACTGAATGTCCAACATCAGATGTTGAAAAGCCAACACGAGGAGCTAAAGAAA
CAGCACAGTGACTTGGAAGAGGAACATCGCAAACAAGGGGAAGACTTCAGTAGAACATTTAATGACCATAAGCAAAAATACTTGCAGCTC
CAGCAAGAAAAAGAACAAGAACTTTCTAAGCTAAAAGAGACTGTATACAATTTGAGAGAAGAGAATAGACAACTAAGGAAAGCACACCAA
GACATACATACACAGCTTCAAGATGTCAAGCAACAGCATAAGAATTTACTCTCCGAGCATGAACAACTTGTAGTGACTTTGGAAGACCAC
AAGAGTGCACTAGCTGCTGCACAGACTCAAGTTGCAGAATATAAACAACTGAAAGATACTCTGAATAGGATTCCAAGCCTTCGAAAACCT
GATCCAGCAGAACAGCAAAATGTGACCCAGGTGGCACATTCTCCACAAGGTTACAACACAGCAAGGGAGAAGCCAACCCGAGAGGTGCAG
GAGGTGTCTCGAAATAATGATGTGTGGCAGAACCATGAAGCAGTTCCTGGAAGAGCAGAAGACACAAAACTCTATGCTCCCACCCATAAG
GAGGCAGAATTTCAGGCTCCCCCAGAGCCAATCCAACAAGAAGTGGAACGCAGAGAACCTGAGGAGCATCAGGTGGAAGAGGAGCACAGA
AAGGCCCTGGAGGAGGAAGAAATGGAGCAGGTCGGGCAAGCAGAACATCTTGAGGAGGAACACGATCCATCACCAGAGGAGCAGGATCGG
GAGTGGAAAGAGCAGCATGAGCAACGAGAAGCAGCCAACCTCCTGGAAGGGCACGCGCGTGCTGAGGTGTACCCTTCAGCCAAGCCAATG
ATCAAATTCCAATCACCCTATGAGGAACAGTTGGAACAGCAGAGACTGGCAGTGCAGCAGGTGGAGGAGGCCCAGCAGCTGCGGGAACAC
CAGGAAGCTTTGCACCAGCAGAGGCTGCAGGGGCACTTACTACGGCAGCAGGAACAGCAGCAGCAGCAGGTGGCAAGAGAGATGGCCCTG
CAGAGGCAGGCTGAGCTTGAGGAGGGCCGGCCGCAGCACCAGGAGCAGCTCCGGCAGCAAGCTCATTATGATGCTATGGATAATGATATC
GTTCAGGGAGCAGAGGACCAGGGAATCCAAGGAGAGGAAGGAGCCTATGAAAGAGACAACCAGCACCAAGATGAAGCAGAAGGAGATCCA
GGTAATAGACATGAGCCTCGTGAACAAGGACCCCGAGAAGCCGACCCAGAATCTGAGGCAGATAGGGCAGCTGTAGAAGATATAAACCCA
GCAGATGACCCTAATAATCAAGGTGAGGATGAATTTGAAGAAGCCGAGCAAGTGAGAGAAGAAAATTTGCCAGATGAAAATGAAGAGCAA
AAACAAAGTAATCAAAAGCAAGAGAATACAGAAGTGGAGGAACATTTGGTGATGGCAGGAAATCCAGACCAGCAGGAGGACAATGTTGAT
GAACAGTACCAGGAAGAGGCAGAAGAGGAGGGAGATCGGATGTGGCACTTTGCGGTGTCTGTGTTTCTGGTAGAGCTCTATGGAAACAGC
CTCCTTTTGACAGCAGTCTACGGGCTGGTGGTGGCAGGGTCTGTTCTGGTCCTGGGAGCCATCATCGGTGACTGGGTGGACAAGAATGCT
AGACTTAAAGTGGCCCAGACCTCGCTGGTGGTACAGAATGTTTCAGTCATCCTGTGTGGAATCATCCTGATGATGGTTTTCTTACATAAA
CATGAGCTTCTGACCATGTACCATGGATGGGTTCTCACTTCCTGCTATATCCTGATCATCACTATTGCAAATATTGCAAATTTGGCCAGT
ACTGCTACTGCAATCACAATCCAAAGGGATTGGATTGTTGTTGTTGCAGGAGAAGACAGAAGCAAACTAGCAAATATGAATGCCACAATA
CGAAGGATTGACCAGTTAACCAACATCTTAGCCCCCATGGCTGTTGGCCAGATTATGACATTTGGCTCCCCAGTCATCGGCTGTGGCTTT
ATTTCGGGATGGAACTTGGTATCCATGTGCGTGGAGTACGTTCTGCTCTGGAAGGTTTACCAGAAAACCCCAGCTCTAGCTGTGAAAGCT
GGTCTTAAAGAAGAGGAAACTGAATTGAAACAGCTGAATTTACACAAAGATACTGAGCCAAAACCCCTGGAGGGAACTCATCTAATGGGT
GTGAAAGACTCTAACATCCATGAGCTTGAACATGAGCAAGAGCCTACTTGTGCCTCCCAGATGGCTGAGCCCTTCCGTACCTTCCGAGAT
GGATGGGTCTCCTACTACAACCAGCCTGTGTTTCTGGCTGGCATGGGTCTTGCTTTCCTTTATATGACTGTCCTGGGCTTTGACTGCATC
ACCACAGGGTACGCCTACACTCAGGGACTGAGTGGTTCCATCCTCAGTATTTTGATGGGAGCATCAGCTATAACTGGAATAATGGGAACT
GTAGCTTTTACTTGGCTACGTCGAAAATGTGGTTTGGTTCGGACAGGTCTGATCTCAGGATTGGCACAGCTTTCCTGTTTGATCTTGTGT
GTGATCTCTGTATTCATGCCTGGAAGCCCCCTGGACTTGTCCGTTTCTCCTTTTGAAGATATCCGATCAAGGTTCATTCAAGGAGAGTCA
ATTACACCTACCAAGATACCTGAAATTACAACTGAAATATACATGTCTAATGGGTCTAATTCTGCTAATATTGTCCCGGAGACAAGTCCT
GAATCTGTGCCCATAATCTCTGTCAGTCTGCTGTTTGCAGGCGTCATTGCTGCTAGAATCGGTCTTTGGTCCTTTGATTTAACTGTGACA
CAGTTGCTGCAAGAAAATGTAATTGAATCTGAAAGAGGCATTATAAATGGTGTACAGAACTCCATGAACTATCTTCTTGATCTTCTGCAT
TTCATCATGGTCATCCTGGCTCCAAATCCTGAAGCTTTTGGCTTGCTCGTATTGATTTCAGTCTCCTTTGTGGCAATGGGCCACATTATG
TATTTCCGATTTGCCCAAAATACTCTGGGAAACAAGCTCTTTGCTTGCGGTCCTGATGCAAAAGAAGTTAGGAAGGAAAATCAAGCAAAT
ACATCTGTTGTTTGAGACAGTTTAACTGTTGCTATCCTGTTACTAGATTATATAGAGCACATGTGCTTATTTTGTACTGCAGAATTCCAA
TAAATGGCTGGGTGTTTTGCTCTGTTTTTACCACAGCTGTGCCTTGAGAACTAAAAGCTGTTTAGGAAACCTAAGTCAGCAGAAATTAAC
TGATTAATTTCCCTTATGTTGAGGCATGGAAAAAAAATTGGAAAAGAAAAACTCAGTTTAAATACGGAGACTATAATGATAACACTGAAT
TCCCCTATTTCTCATGAGTAGATACAATCTTACGTAAAAGAGTGGTTAGTCACGTGAATTCAGTTATCATTTGACAGATTCTTATCTGTA
CTAGAATTCAGATATGTCAGTTTTCTGCAAAACTCACTCTTGTTCAAGACTAGCTAATTTATTTTTTTGCATCTTAGTTATTTTTAAAAA
CAAATTCTTCAAGTATGAAGACTAAATTTTGATAACTAATATTATCCTTATTGATCCTATTGATCTTAAGGTATTTACATGTATGTGGAA
AAACAAAACACTTAACTAGAATTCTCTAATAAGGTTTATGGTTTAGCTTAAAGAGCACCTTTGTATTTTTATTATCAGATGGGGCAACAT
ATTGTATGAAGCATATGTAGCACTTCACAGCATGGTTATCATGTAAGCTGCAGGTAGAAGCAAAGCTGTAAAGTAGATTTATCACACAAT
GACTGCATACAGACTTCAAATATGTCAATAGTTTGGTCATAGAACCTAGAAGCCAAAAGCCACACAGAAGGGCAAGAATCCCAATTTAAC
TCATGTTATCATCATTAGTGATCTGTGTTGTAGAACATGAGGGTGTAAGCCTTCAGCCTGGCAAGTTACATGTAGAAAGCCCACACTTGT
GAAGGTTTTGTTTTACAAATCACTTGATTTAACACACTCAGGTAGAATATTTTTATTTTTACTGTTTTATACCCAGAAGTTATTTCTACA
TTGTTCTACAGCAAGAATATTCATAAAAGTATCCCTTTCAAATGCCTTTGAGAAGAATAGAAGAAAAAAAGTTTGTATATATTTTAAAAA
ATTGTTTTAAAAGTCAGTTTGCAACATGTCTGTACCAAGATGGTACTTTGCCTTAACCGTTTATATGCACTTTCATGGAGACTGCAATAC
GTTGCTATGAGCACTTTCTTTATCCTTGGAGTTTAATCCTTTGCTTCATCTTTCTACAGTATGACATAATGATTTGCTATGTTGTAAAAT

>33955_33955_4_GOLIM4-SLC40A1_GOLIM4_chr3_167742314_ENST00000470487_SLC40A1_chr2_190440046_ENST00000261024_length(amino acids)=1160AA_BP=626
MGPGGTMGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQLQVVYEHRSRLEKSLQKERLEHKK
AKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKET
VYNLREENRQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHS
PQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQA
EHLEEEHDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLL
RQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREA
DPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEGDRM
WHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLTS
CYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYV
LLWKVYQKTPALAVKAGLKEEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLAG
MGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLS
VSPFEDIRSRFIQGESITPTKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGI

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Fusion Gene PPI Analysis for GOLIM4-SLC40A1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GOLIM4-SLC40A1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GOLIM4-SLC40A1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource