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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GOLPH3-IKZF3 (FusionGDB2 ID:33968)

Fusion Gene Summary for GOLPH3-IKZF3

check button Fusion gene summary
Fusion gene informationFusion gene name: GOLPH3-IKZF3
Fusion gene ID: 33968
HgeneTgene
Gene symbol

GOLPH3

IKZF3

Gene ID

64083

22806

Gene namegolgi phosphoprotein 3IKAROS family zinc finger 3
SynonymsGOPP1|GPP34|MIDAS|Vps74AIO|AIOLOS|ZNFN1A3
Cytomap

5p13.3

17q12-q21.1

Type of geneprotein-codingprotein-coding
DescriptionGolgi phosphoprotein 3coat protein GPP34coat-proteingolgi peripheral membrane protein 1, 34 kDagolgi proteingolgi-associated proteinmitochondrial DNA absence factorzinc finger protein Aioloszinc finger DNA binding protein Aioloszinc finger protein, subfamily 1A, 3 (Aiolos)
Modification date2020032920200327
UniProtAcc

Q9H4A6

Q9UKT9

Ensembl transtripts involved in fusion geneENST00000265070, ENST00000512668, 
ENST00000583368, ENST00000346243, 
ENST00000350532, ENST00000351680, 
ENST00000377944, ENST00000377945, 
ENST00000377952, ENST00000377958, 
ENST00000394189, ENST00000439016, 
ENST00000439167, ENST00000467757, 
ENST00000535189, ENST00000346872, 
Fusion gene scores* DoF score11 X 10 X 7=77034 X 12 X 14=5712
# samples 1649
** MAII scorelog2(16/770*10)=-2.2667865406949
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(49/5712*10)=-3.54314232502653
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GOLPH3 [Title/Abstract] AND IKZF3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGOLPH3(32173916)-IKZF3(37944627), # samples:3
Anticipated loss of major functional domain due to fusion event.GOLPH3-IKZF3 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
GOLPH3-IKZF3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
GOLPH3-IKZF3 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
GOLPH3-IKZF3 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneGOLPH3

GO:0010821

regulation of mitochondrion organization

16263763


check buttonFusion gene breakpoints across GOLPH3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across IKZF3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-L5-A8NI-01AGOLPH3chr5

32173916

-IKZF3chr17

37944627

-
ChimerDB4ESCATCGA-L5-A8NIGOLPH3chr5

32173915

-IKZF3chr17

37922746

-
ChimerDB4ESCATCGA-L5-A8NIGOLPH3chr5

32173915

-IKZF3chr17

37934020

-
ChimerDB4ESCATCGA-L5-A8NIGOLPH3chr5

32173916

-IKZF3chr17

37922746

-
ChimerDB4ESCATCGA-L5-A8NIGOLPH3chr5

32173916

-IKZF3chr17

37934020

-
ChimerDB4ESCATCGA-L5-A8NIGOLPH3chr5

32173916

-IKZF3chr17

37944627

-


Top

Fusion Gene ORF analysis for GOLPH3-IKZF3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000265070ENST00000583368GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5CDS-5UTRENST00000265070ENST00000583368GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000346243GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5CDS-intronENST00000265070ENST00000346243GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000346243GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000350532GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5CDS-intronENST00000265070ENST00000350532GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000350532GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000351680GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5CDS-intronENST00000265070ENST00000351680GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000351680GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000377944GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5CDS-intronENST00000265070ENST00000377945GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5CDS-intronENST00000265070ENST00000377945GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000377945GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000377952GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5CDS-intronENST00000265070ENST00000377952GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000377952GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000377958GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5CDS-intronENST00000265070ENST00000377958GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000377958GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000394189GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5CDS-intronENST00000265070ENST00000439016GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5CDS-intronENST00000265070ENST00000439016GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000439016GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000439167GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5CDS-intronENST00000265070ENST00000467757GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5CDS-intronENST00000265070ENST00000467757GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000467757GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5CDS-intronENST00000265070ENST00000535189GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5CDS-intronENST00000265070ENST00000583368GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-3CDSENST00000512668ENST00000346243GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000346243GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000346872GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-3CDSENST00000512668ENST00000346872GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000346872GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-3CDSENST00000512668ENST00000346872GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000346872GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-3CDSENST00000512668ENST00000350532GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000350532GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000351680GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000351680GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000377944GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000377944GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-3CDSENST00000512668ENST00000377944GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000377944GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-3CDSENST00000512668ENST00000377945GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000377945GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000377952GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000377952GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000377958GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000377958GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000394189GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000394189GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-3CDSENST00000512668ENST00000394189GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000394189GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-3CDSENST00000512668ENST00000439016GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000439016GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000439167GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000439167GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-3CDSENST00000512668ENST00000439167GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000439167GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-3CDSENST00000512668ENST00000467757GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000467757GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000535189GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000535189GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-3CDSENST00000512668ENST00000535189GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000535189GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-3CDSENST00000512668ENST00000583368GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
5UTR-3CDSENST00000512668ENST00000583368GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
5UTR-5UTRENST00000512668ENST00000583368GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-5UTRENST00000512668ENST00000583368GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000346243GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-intronENST00000512668ENST00000346243GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000346243GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000350532GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-intronENST00000512668ENST00000350532GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000350532GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000351680GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-intronENST00000512668ENST00000351680GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000351680GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000377944GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-intronENST00000512668ENST00000377945GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-intronENST00000512668ENST00000377945GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000377945GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000377952GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-intronENST00000512668ENST00000377952GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000377952GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000377958GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-intronENST00000512668ENST00000377958GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000377958GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000394189GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-intronENST00000512668ENST00000439016GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-intronENST00000512668ENST00000439016GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000439016GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000439167GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-intronENST00000512668ENST00000467757GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-intronENST00000512668ENST00000467757GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000467757GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
5UTR-intronENST00000512668ENST00000535189GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
5UTR-intronENST00000512668ENST00000583368GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
Frame-shiftENST00000265070ENST00000346872GOLPH3chr5

32173916

-IKZF3chr17

37944627

-
Frame-shiftENST00000265070ENST00000346872GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000346872GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
Frame-shiftENST00000265070ENST00000346872GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000346872GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
Frame-shiftENST00000265070ENST00000377944GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000377944GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
Frame-shiftENST00000265070ENST00000377944GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000377944GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
Frame-shiftENST00000265070ENST00000377945GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000377945GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000377952GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000377952GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000377958GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000377958GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000394189GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000394189GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
Frame-shiftENST00000265070ENST00000394189GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000394189GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
Frame-shiftENST00000265070ENST00000439016GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000439016GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000439167GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000439167GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
Frame-shiftENST00000265070ENST00000439167GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000439167GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
Frame-shiftENST00000265070ENST00000535189GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000535189GOLPH3chr5

32173915

-IKZF3chr17

37934020

-
Frame-shiftENST00000265070ENST00000535189GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000535189GOLPH3chr5

32173916

-IKZF3chr17

37934020

-
Frame-shiftENST00000265070ENST00000583368GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
Frame-shiftENST00000265070ENST00000583368GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
In-frameENST00000265070ENST00000346243GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
In-frameENST00000265070ENST00000346243GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
In-frameENST00000265070ENST00000350532GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
In-frameENST00000265070ENST00000350532GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
In-frameENST00000265070ENST00000351680GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
In-frameENST00000265070ENST00000351680GOLPH3chr5

32173916

-IKZF3chr17

37922746

-
In-frameENST00000265070ENST00000467757GOLPH3chr5

32173915

-IKZF3chr17

37922746

-
In-frameENST00000265070ENST00000467757GOLPH3chr5

32173916

-IKZF3chr17

37922746

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000265070GOLPH3chr532173915-ENST00000346243IKZF3chr1737922746-12455411171244375
ENST00000265070GOLPH3chr532173915-ENST00000350532IKZF3chr1737922746-12455411171244375
ENST00000265070GOLPH3chr532173915-ENST00000351680IKZF3chr1737922746-12455411171244375
ENST00000265070GOLPH3chr532173915-ENST00000467757IKZF3chr1737922746-12455411171244375
ENST00000265070GOLPH3chr532173916-ENST00000346243IKZF3chr1737922746-12455411171244375
ENST00000265070GOLPH3chr532173916-ENST00000350532IKZF3chr1737922746-12455411171244375
ENST00000265070GOLPH3chr532173916-ENST00000351680IKZF3chr1737922746-12455411171244375
ENST00000265070GOLPH3chr532173916-ENST00000467757IKZF3chr1737922746-12455411171244375

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000265070ENST00000346243GOLPH3chr532173915-IKZF3chr1737922746-0.0015420170.998458
ENST00000265070ENST00000350532GOLPH3chr532173915-IKZF3chr1737922746-0.0015420170.998458
ENST00000265070ENST00000351680GOLPH3chr532173915-IKZF3chr1737922746-0.0015420170.998458
ENST00000265070ENST00000467757GOLPH3chr532173915-IKZF3chr1737922746-0.0015420170.998458
ENST00000265070ENST00000346243GOLPH3chr532173916-IKZF3chr1737922746-0.0015420170.998458
ENST00000265070ENST00000350532GOLPH3chr532173916-IKZF3chr1737922746-0.0015420170.998458
ENST00000265070ENST00000351680GOLPH3chr532173916-IKZF3chr1737922746-0.0015420170.998458
ENST00000265070ENST00000467757GOLPH3chr532173916-IKZF3chr1737922746-0.0015420170.998458

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Fusion Genomic Features for GOLPH3-IKZF3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GOLPH3-IKZF3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:32173916/chr17:37944627)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GOLPH3

Q9H4A6

IKZF3

Q9UKT9

FUNCTION: Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Has also been involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part. May play an indirect role in cell migration. Has also been involved in the modulation of mTOR signaling. May also be involved in the regulation of mitochondrial lipids biosynthesis. {ECO:0000269|PubMed:16263763, ECO:0000269|PubMed:19553991, ECO:0000269|PubMed:19837035, ECO:0000269|PubMed:22745132, ECO:0000269|PubMed:23027862, ECO:0000269|PubMed:23345592, ECO:0000269|PubMed:23500462}.FUNCTION: Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner. {ECO:0000269|PubMed:10369681}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGOLPH3chr5:32173915chr17:37922746ENST00000265070-1448_5175299.0Compositional biasNote=Poly-Asp
HgeneGOLPH3chr5:32173916chr17:37922746ENST00000265070-1448_5175299.0Compositional biasNote=Poly-Asp
TgeneIKZF3chr5:32173915chr17:37922746ENST0000034624346202_224197432.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000034624346452_474197432.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173915chr17:37922746ENST0000034624346480_504197432.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000034687268452_474275510.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173915chr17:37922746ENST0000034687268480_504275510.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000035053257452_474236471.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173915chr17:37922746ENST0000035053257480_504236471.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000035168057452_474236471.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173915chr17:37922746ENST0000035168057480_504236471.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037794446146_168132367.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037794446174_196132367.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037794446202_224132367.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037794446452_474132367.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037794446480_504132367.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037794535146_168141376.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037794535174_196141376.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037794535202_224141376.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037794535452_474141376.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037794535480_504141376.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037795224118_14054289.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037795224146_16854289.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037795224174_19654289.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037795224202_22454289.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037795224452_47454289.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037795224480_50454289.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037795857202_224188423.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037795857452_474188423.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037795857480_504188423.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000039418935118_14093328.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173915chr17:37922746ENST0000039418935146_16893328.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173915chr17:37922746ENST0000039418935174_19693328.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173915chr17:37922746ENST0000039418935202_22493328.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000039418935452_47493328.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173915chr17:37922746ENST0000039418935480_50493328.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000043901646202_224180415.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000043901646452_474180415.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173915chr17:37922746ENST0000043901646480_504180415.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000043916746202_224202437.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000043916746452_474202437.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173915chr17:37922746ENST0000043916746480_504202437.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000046775757452_474219454.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173915chr17:37922746ENST0000046775757480_504219454.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000053518957452_474241476.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173915chr17:37922746ENST0000053518957480_504241476.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000034624346202_224197432.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000034624346452_474197432.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173916chr17:37922746ENST0000034624346480_504197432.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000034687268452_474275510.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173916chr17:37922746ENST0000034687268480_504275510.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000035053257452_474236471.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173916chr17:37922746ENST0000035053257480_504236471.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000035168057452_474236471.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173916chr17:37922746ENST0000035168057480_504236471.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037794446146_168132367.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037794446174_196132367.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037794446202_224132367.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037794446452_474132367.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037794446480_504132367.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037794535146_168141376.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037794535174_196141376.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037794535202_224141376.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037794535452_474141376.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037794535480_504141376.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037795224118_14054289.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037795224146_16854289.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037795224174_19654289.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037795224202_22454289.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037795224452_47454289.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037795224480_50454289.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037795857202_224188423.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037795857452_474188423.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037795857480_504188423.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000039418935118_14093328.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173916chr17:37922746ENST0000039418935146_16893328.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173916chr17:37922746ENST0000039418935174_19693328.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173916chr17:37922746ENST0000039418935202_22493328.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000039418935452_47493328.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173916chr17:37922746ENST0000039418935480_50493328.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000043901646202_224180415.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000043901646452_474180415.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173916chr17:37922746ENST0000043901646480_504180415.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000043916746202_224202437.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000043916746452_474202437.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173916chr17:37922746ENST0000043916746480_504202437.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000046775757452_474219454.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173916chr17:37922746ENST0000046775757480_504219454.0Zinc fingerC2H2-type 6%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000053518957452_474241476.0Zinc fingerC2H2-type 5
TgeneIKZF3chr5:32173916chr17:37922746ENST0000053518957480_504241476.0Zinc fingerC2H2-type 6%3B atypical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGOLPH3chr5:32173915chr17:37922746ENST00000265070-14190_20175299.0RegionBeta-hairpin required for oligomerization
HgeneGOLPH3chr5:32173916chr17:37922746ENST00000265070-14190_20175299.0RegionBeta-hairpin required for oligomerization
TgeneIKZF3chr5:32173915chr17:37922746ENST0000034624346118_140197432.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173915chr17:37922746ENST0000034624346146_168197432.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173915chr17:37922746ENST0000034624346174_196197432.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173915chr17:37922746ENST0000034687268118_140275510.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173915chr17:37922746ENST0000034687268146_168275510.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173915chr17:37922746ENST0000034687268174_196275510.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173915chr17:37922746ENST0000034687268202_224275510.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000035053257118_140236471.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173915chr17:37922746ENST0000035053257146_168236471.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173915chr17:37922746ENST0000035053257174_196236471.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173915chr17:37922746ENST0000035053257202_224236471.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000035168057118_140236471.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173915chr17:37922746ENST0000035168057146_168236471.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173915chr17:37922746ENST0000035168057174_196236471.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173915chr17:37922746ENST0000035168057202_224236471.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037794446118_140132367.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037794535118_140141376.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037795857118_140188423.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037795857146_168188423.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173915chr17:37922746ENST0000037795857174_196188423.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173915chr17:37922746ENST0000043901646118_140180415.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173915chr17:37922746ENST0000043901646146_168180415.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173915chr17:37922746ENST0000043901646174_196180415.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173915chr17:37922746ENST0000043916746118_140202437.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173915chr17:37922746ENST0000043916746146_168202437.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173915chr17:37922746ENST0000043916746174_196202437.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173915chr17:37922746ENST0000046775757118_140219454.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173915chr17:37922746ENST0000046775757146_168219454.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173915chr17:37922746ENST0000046775757174_196219454.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173915chr17:37922746ENST0000046775757202_224219454.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173915chr17:37922746ENST0000053518957118_140241476.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173915chr17:37922746ENST0000053518957146_168241476.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173915chr17:37922746ENST0000053518957174_196241476.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173915chr17:37922746ENST0000053518957202_224241476.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000034624346118_140197432.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173916chr17:37922746ENST0000034624346146_168197432.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173916chr17:37922746ENST0000034624346174_196197432.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173916chr17:37922746ENST0000034687268118_140275510.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173916chr17:37922746ENST0000034687268146_168275510.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173916chr17:37922746ENST0000034687268174_196275510.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173916chr17:37922746ENST0000034687268202_224275510.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000035053257118_140236471.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173916chr17:37922746ENST0000035053257146_168236471.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173916chr17:37922746ENST0000035053257174_196236471.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173916chr17:37922746ENST0000035053257202_224236471.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000035168057118_140236471.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173916chr17:37922746ENST0000035168057146_168236471.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173916chr17:37922746ENST0000035168057174_196236471.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173916chr17:37922746ENST0000035168057202_224236471.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037794446118_140132367.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037794535118_140141376.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037795857118_140188423.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037795857146_168188423.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173916chr17:37922746ENST0000037795857174_196188423.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173916chr17:37922746ENST0000043901646118_140180415.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173916chr17:37922746ENST0000043901646146_168180415.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173916chr17:37922746ENST0000043901646174_196180415.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173916chr17:37922746ENST0000043916746118_140202437.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173916chr17:37922746ENST0000043916746146_168202437.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173916chr17:37922746ENST0000043916746174_196202437.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173916chr17:37922746ENST0000046775757118_140219454.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173916chr17:37922746ENST0000046775757146_168219454.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173916chr17:37922746ENST0000046775757174_196219454.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173916chr17:37922746ENST0000046775757202_224219454.0Zinc fingerC2H2-type 4%3B atypical
TgeneIKZF3chr5:32173916chr17:37922746ENST0000053518957118_140241476.0Zinc fingerC2H2-type 1
TgeneIKZF3chr5:32173916chr17:37922746ENST0000053518957146_168241476.0Zinc fingerC2H2-type 2
TgeneIKZF3chr5:32173916chr17:37922746ENST0000053518957174_196241476.0Zinc fingerC2H2-type 3
TgeneIKZF3chr5:32173916chr17:37922746ENST0000053518957202_224241476.0Zinc fingerC2H2-type 4%3B atypical


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Fusion Gene Sequence for GOLPH3-IKZF3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>33968_33968_1_GOLPH3-IKZF3_GOLPH3_chr5_32173915_ENST00000265070_IKZF3_chr17_37922746_ENST00000346243_length(transcript)=1245nt_BP=541nt
ACATCCTCCGGTGACGTCAGCCGGGGCCGCCATATTGGAAAGGCGCCGCCGCCGCCTCCGCCTTGGAGCTCGGGGTGTTTCGGGGACTGC
GGCCACAGGCAGGAAGGCGCTCCTCTCCTGCCCCGCCGACGCCCGGCCAGCCCGCTTCGCCCTGACCTGTTTCCTCATGACTGCCCCCGG
CCCTGCTGCCGACGGACGTCGCCCCGGCGTCCGGATTTAACACGGAAACCCGGATCGGAGGCCGCGCGGGGAGGAGGAGGGCGACCCGGT
CGGTCCTGCGACCCTCTCGGCCCGGCTCGGCGCCTCGGCGGGAGCCATGACCTCGCTGACCCAGCGCAGCTCCGGCCTGGTGCAGCGGCG
CACCGAGGCCTCCCGCAACGCCGCCGACAAGGAGCGGGCGGCGGGCGGCGGCGCCGGCAGCAGCGAGGACGACGCGCAGAGCCGCCGCGA
CGAGCAGGACGACGACGACAAGGGCGACTCCAAGGAAACGCGGCTGACCCTGATGGAGGAAGTGCTCCTGCTGGGCCTCAAGGACCGCGA
GGTGAGAAGCGCCACTGCTTTGATGTCAACTATAATTCAAGTTACATGTATGAGAAAGAGAGTGAGCTCATACAGACCCGCATGATGGAC
CAAGCCATCAATAACGCCATCAGCTATCTTGGCGCCGAAGCCCTGCGCCCCTTGGTCCAGACACCGCCTGCTCCCACCTCGGAGATGGTT
CCAGTTATCAGCAGCATGTATCCCATAGCCCTCACCCGGGCTGAGATGTCAAACGGTGCCCCTCAAGAGCTGGAAAAGAAAAGCATCCAC
CTTCCAGAGAAGAGCGTGCCTTCTGAGAGAGGCCTCTCTCCCAACAATAGTGGCCACGACTCCACGGACACTGACAGCAACCATGAAGAA
CGCCAGAATCACATCTATCAGCAAAATCACATGGTCCTGTCTCGGGCCCGCAATGGGATGCCACTTCTGAAGGAGGTTCCCCGCTCTTAC
GAACTCCTCAAGCCCCCGCCCATCTGCCCAAGAGACTCCGTCAAAGTGATCAACAAGGAAGGGGAGGTGATGGATGTGTATCGGTGTGAC
CACTGCCGCGTCCTCTTCCTGGACTATGTGATGTTCACGATTCACATGGGCTGCCACGGCTTCCGTGACCCTTTCGAGTGTAACATGTGT

>33968_33968_1_GOLPH3-IKZF3_GOLPH3_chr5_32173915_ENST00000265070_IKZF3_chr17_37922746_ENST00000346243_length(amino acids)=375AA_BP=89
MPRRRPASPLRPDLFPHDCPRPCCRRTSPRRPDLTRKPGSEAARGGGGRPGRSCDPLGPARRLGGSHDLADPAQLRPGAAAHRGLPQRRR
QGAGGGRRRRQQRGRRAEPPRRAGRRRQGRLQGNAADPDGGSAPAGPQGPRGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISY
LGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQN
HMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYE

--------------------------------------------------------------
>33968_33968_2_GOLPH3-IKZF3_GOLPH3_chr5_32173915_ENST00000265070_IKZF3_chr17_37922746_ENST00000350532_length(transcript)=1245nt_BP=541nt
ACATCCTCCGGTGACGTCAGCCGGGGCCGCCATATTGGAAAGGCGCCGCCGCCGCCTCCGCCTTGGAGCTCGGGGTGTTTCGGGGACTGC
GGCCACAGGCAGGAAGGCGCTCCTCTCCTGCCCCGCCGACGCCCGGCCAGCCCGCTTCGCCCTGACCTGTTTCCTCATGACTGCCCCCGG
CCCTGCTGCCGACGGACGTCGCCCCGGCGTCCGGATTTAACACGGAAACCCGGATCGGAGGCCGCGCGGGGAGGAGGAGGGCGACCCGGT
CGGTCCTGCGACCCTCTCGGCCCGGCTCGGCGCCTCGGCGGGAGCCATGACCTCGCTGACCCAGCGCAGCTCCGGCCTGGTGCAGCGGCG
CACCGAGGCCTCCCGCAACGCCGCCGACAAGGAGCGGGCGGCGGGCGGCGGCGCCGGCAGCAGCGAGGACGACGCGCAGAGCCGCCGCGA
CGAGCAGGACGACGACGACAAGGGCGACTCCAAGGAAACGCGGCTGACCCTGATGGAGGAAGTGCTCCTGCTGGGCCTCAAGGACCGCGA
GGTGAGAAGCGCCACTGCTTTGATGTCAACTATAATTCAAGTTACATGTATGAGAAAGAGAGTGAGCTCATACAGACCCGCATGATGGAC
CAAGCCATCAATAACGCCATCAGCTATCTTGGCGCCGAAGCCCTGCGCCCCTTGGTCCAGACACCGCCTGCTCCCACCTCGGAGATGGTT
CCAGTTATCAGCAGCATGTATCCCATAGCCCTCACCCGGGCTGAGATGTCAAACGGTGCCCCTCAAGAGCTGGAAAAGAAAAGCATCCAC
CTTCCAGAGAAGAGCGTGCCTTCTGAGAGAGGCCTCTCTCCCAACAATAGTGGCCACGACTCCACGGACACTGACAGCAACCATGAAGAA
CGCCAGAATCACATCTATCAGCAAAATCACATGGTCCTGTCTCGGGCCCGCAATGGGATGCCACTTCTGAAGGAGGTTCCCCGCTCTTAC
GAACTCCTCAAGCCCCCGCCCATCTGCCCAAGAGACTCCGTCAAAGTGATCAACAAGGAAGGGGAGGTGATGGATGTGTATCGGTGTGAC
CACTGCCGCGTCCTCTTCCTGGACTATGTGATGTTCACGATTCACATGGGCTGCCACGGCTTCCGTGACCCTTTCGAGTGTAACATGTGT

>33968_33968_2_GOLPH3-IKZF3_GOLPH3_chr5_32173915_ENST00000265070_IKZF3_chr17_37922746_ENST00000350532_length(amino acids)=375AA_BP=89
MPRRRPASPLRPDLFPHDCPRPCCRRTSPRRPDLTRKPGSEAARGGGGRPGRSCDPLGPARRLGGSHDLADPAQLRPGAAAHRGLPQRRR
QGAGGGRRRRQQRGRRAEPPRRAGRRRQGRLQGNAADPDGGSAPAGPQGPRGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISY
LGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQN
HMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYE

--------------------------------------------------------------
>33968_33968_3_GOLPH3-IKZF3_GOLPH3_chr5_32173915_ENST00000265070_IKZF3_chr17_37922746_ENST00000351680_length(transcript)=1245nt_BP=541nt
ACATCCTCCGGTGACGTCAGCCGGGGCCGCCATATTGGAAAGGCGCCGCCGCCGCCTCCGCCTTGGAGCTCGGGGTGTTTCGGGGACTGC
GGCCACAGGCAGGAAGGCGCTCCTCTCCTGCCCCGCCGACGCCCGGCCAGCCCGCTTCGCCCTGACCTGTTTCCTCATGACTGCCCCCGG
CCCTGCTGCCGACGGACGTCGCCCCGGCGTCCGGATTTAACACGGAAACCCGGATCGGAGGCCGCGCGGGGAGGAGGAGGGCGACCCGGT
CGGTCCTGCGACCCTCTCGGCCCGGCTCGGCGCCTCGGCGGGAGCCATGACCTCGCTGACCCAGCGCAGCTCCGGCCTGGTGCAGCGGCG
CACCGAGGCCTCCCGCAACGCCGCCGACAAGGAGCGGGCGGCGGGCGGCGGCGCCGGCAGCAGCGAGGACGACGCGCAGAGCCGCCGCGA
CGAGCAGGACGACGACGACAAGGGCGACTCCAAGGAAACGCGGCTGACCCTGATGGAGGAAGTGCTCCTGCTGGGCCTCAAGGACCGCGA
GGTGAGAAGCGCCACTGCTTTGATGTCAACTATAATTCAAGTTACATGTATGAGAAAGAGAGTGAGCTCATACAGACCCGCATGATGGAC
CAAGCCATCAATAACGCCATCAGCTATCTTGGCGCCGAAGCCCTGCGCCCCTTGGTCCAGACACCGCCTGCTCCCACCTCGGAGATGGTT
CCAGTTATCAGCAGCATGTATCCCATAGCCCTCACCCGGGCTGAGATGTCAAACGGTGCCCCTCAAGAGCTGGAAAAGAAAAGCATCCAC
CTTCCAGAGAAGAGCGTGCCTTCTGAGAGAGGCCTCTCTCCCAACAATAGTGGCCACGACTCCACGGACACTGACAGCAACCATGAAGAA
CGCCAGAATCACATCTATCAGCAAAATCACATGGTCCTGTCTCGGGCCCGCAATGGGATGCCACTTCTGAAGGAGGTTCCCCGCTCTTAC
GAACTCCTCAAGCCCCCGCCCATCTGCCCAAGAGACTCCGTCAAAGTGATCAACAAGGAAGGGGAGGTGATGGATGTGTATCGGTGTGAC
CACTGCCGCGTCCTCTTCCTGGACTATGTGATGTTCACGATTCACATGGGCTGCCACGGCTTCCGTGACCCTTTCGAGTGTAACATGTGT

>33968_33968_3_GOLPH3-IKZF3_GOLPH3_chr5_32173915_ENST00000265070_IKZF3_chr17_37922746_ENST00000351680_length(amino acids)=375AA_BP=89
MPRRRPASPLRPDLFPHDCPRPCCRRTSPRRPDLTRKPGSEAARGGGGRPGRSCDPLGPARRLGGSHDLADPAQLRPGAAAHRGLPQRRR
QGAGGGRRRRQQRGRRAEPPRRAGRRRQGRLQGNAADPDGGSAPAGPQGPRGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISY
LGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQN
HMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYE

--------------------------------------------------------------
>33968_33968_4_GOLPH3-IKZF3_GOLPH3_chr5_32173915_ENST00000265070_IKZF3_chr17_37922746_ENST00000467757_length(transcript)=1245nt_BP=541nt
ACATCCTCCGGTGACGTCAGCCGGGGCCGCCATATTGGAAAGGCGCCGCCGCCGCCTCCGCCTTGGAGCTCGGGGTGTTTCGGGGACTGC
GGCCACAGGCAGGAAGGCGCTCCTCTCCTGCCCCGCCGACGCCCGGCCAGCCCGCTTCGCCCTGACCTGTTTCCTCATGACTGCCCCCGG
CCCTGCTGCCGACGGACGTCGCCCCGGCGTCCGGATTTAACACGGAAACCCGGATCGGAGGCCGCGCGGGGAGGAGGAGGGCGACCCGGT
CGGTCCTGCGACCCTCTCGGCCCGGCTCGGCGCCTCGGCGGGAGCCATGACCTCGCTGACCCAGCGCAGCTCCGGCCTGGTGCAGCGGCG
CACCGAGGCCTCCCGCAACGCCGCCGACAAGGAGCGGGCGGCGGGCGGCGGCGCCGGCAGCAGCGAGGACGACGCGCAGAGCCGCCGCGA
CGAGCAGGACGACGACGACAAGGGCGACTCCAAGGAAACGCGGCTGACCCTGATGGAGGAAGTGCTCCTGCTGGGCCTCAAGGACCGCGA
GGTGAGAAGCGCCACTGCTTTGATGTCAACTATAATTCAAGTTACATGTATGAGAAAGAGAGTGAGCTCATACAGACCCGCATGATGGAC
CAAGCCATCAATAACGCCATCAGCTATCTTGGCGCCGAAGCCCTGCGCCCCTTGGTCCAGACACCGCCTGCTCCCACCTCGGAGATGGTT
CCAGTTATCAGCAGCATGTATCCCATAGCCCTCACCCGGGCTGAGATGTCAAACGGTGCCCCTCAAGAGCTGGAAAAGAAAAGCATCCAC
CTTCCAGAGAAGAGCGTGCCTTCTGAGAGAGGCCTCTCTCCCAACAATAGTGGCCACGACTCCACGGACACTGACAGCAACCATGAAGAA
CGCCAGAATCACATCTATCAGCAAAATCACATGGTCCTGTCTCGGGCCCGCAATGGGATGCCACTTCTGAAGGAGGTTCCCCGCTCTTAC
GAACTCCTCAAGCCCCCGCCCATCTGCCCAAGAGACTCCGTCAAAGTGATCAACAAGGAAGGGGAGGTGATGGATGTGTATCGGTGTGAC
CACTGCCGCGTCCTCTTCCTGGACTATGTGATGTTCACGATTCACATGGGCTGCCACGGCTTCCGTGACCCTTTCGAGTGTAACATGTGT

>33968_33968_4_GOLPH3-IKZF3_GOLPH3_chr5_32173915_ENST00000265070_IKZF3_chr17_37922746_ENST00000467757_length(amino acids)=375AA_BP=89
MPRRRPASPLRPDLFPHDCPRPCCRRTSPRRPDLTRKPGSEAARGGGGRPGRSCDPLGPARRLGGSHDLADPAQLRPGAAAHRGLPQRRR
QGAGGGRRRRQQRGRRAEPPRRAGRRRQGRLQGNAADPDGGSAPAGPQGPRGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISY
LGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQN
HMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYE

--------------------------------------------------------------
>33968_33968_5_GOLPH3-IKZF3_GOLPH3_chr5_32173916_ENST00000265070_IKZF3_chr17_37922746_ENST00000346243_length(transcript)=1245nt_BP=541nt
ACATCCTCCGGTGACGTCAGCCGGGGCCGCCATATTGGAAAGGCGCCGCCGCCGCCTCCGCCTTGGAGCTCGGGGTGTTTCGGGGACTGC
GGCCACAGGCAGGAAGGCGCTCCTCTCCTGCCCCGCCGACGCCCGGCCAGCCCGCTTCGCCCTGACCTGTTTCCTCATGACTGCCCCCGG
CCCTGCTGCCGACGGACGTCGCCCCGGCGTCCGGATTTAACACGGAAACCCGGATCGGAGGCCGCGCGGGGAGGAGGAGGGCGACCCGGT
CGGTCCTGCGACCCTCTCGGCCCGGCTCGGCGCCTCGGCGGGAGCCATGACCTCGCTGACCCAGCGCAGCTCCGGCCTGGTGCAGCGGCG
CACCGAGGCCTCCCGCAACGCCGCCGACAAGGAGCGGGCGGCGGGCGGCGGCGCCGGCAGCAGCGAGGACGACGCGCAGAGCCGCCGCGA
CGAGCAGGACGACGACGACAAGGGCGACTCCAAGGAAACGCGGCTGACCCTGATGGAGGAAGTGCTCCTGCTGGGCCTCAAGGACCGCGA
GGTGAGAAGCGCCACTGCTTTGATGTCAACTATAATTCAAGTTACATGTATGAGAAAGAGAGTGAGCTCATACAGACCCGCATGATGGAC
CAAGCCATCAATAACGCCATCAGCTATCTTGGCGCCGAAGCCCTGCGCCCCTTGGTCCAGACACCGCCTGCTCCCACCTCGGAGATGGTT
CCAGTTATCAGCAGCATGTATCCCATAGCCCTCACCCGGGCTGAGATGTCAAACGGTGCCCCTCAAGAGCTGGAAAAGAAAAGCATCCAC
CTTCCAGAGAAGAGCGTGCCTTCTGAGAGAGGCCTCTCTCCCAACAATAGTGGCCACGACTCCACGGACACTGACAGCAACCATGAAGAA
CGCCAGAATCACATCTATCAGCAAAATCACATGGTCCTGTCTCGGGCCCGCAATGGGATGCCACTTCTGAAGGAGGTTCCCCGCTCTTAC
GAACTCCTCAAGCCCCCGCCCATCTGCCCAAGAGACTCCGTCAAAGTGATCAACAAGGAAGGGGAGGTGATGGATGTGTATCGGTGTGAC
CACTGCCGCGTCCTCTTCCTGGACTATGTGATGTTCACGATTCACATGGGCTGCCACGGCTTCCGTGACCCTTTCGAGTGTAACATGTGT

>33968_33968_5_GOLPH3-IKZF3_GOLPH3_chr5_32173916_ENST00000265070_IKZF3_chr17_37922746_ENST00000346243_length(amino acids)=375AA_BP=89
MPRRRPASPLRPDLFPHDCPRPCCRRTSPRRPDLTRKPGSEAARGGGGRPGRSCDPLGPARRLGGSHDLADPAQLRPGAAAHRGLPQRRR
QGAGGGRRRRQQRGRRAEPPRRAGRRRQGRLQGNAADPDGGSAPAGPQGPRGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISY
LGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQN
HMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYE

--------------------------------------------------------------
>33968_33968_6_GOLPH3-IKZF3_GOLPH3_chr5_32173916_ENST00000265070_IKZF3_chr17_37922746_ENST00000350532_length(transcript)=1245nt_BP=541nt
ACATCCTCCGGTGACGTCAGCCGGGGCCGCCATATTGGAAAGGCGCCGCCGCCGCCTCCGCCTTGGAGCTCGGGGTGTTTCGGGGACTGC
GGCCACAGGCAGGAAGGCGCTCCTCTCCTGCCCCGCCGACGCCCGGCCAGCCCGCTTCGCCCTGACCTGTTTCCTCATGACTGCCCCCGG
CCCTGCTGCCGACGGACGTCGCCCCGGCGTCCGGATTTAACACGGAAACCCGGATCGGAGGCCGCGCGGGGAGGAGGAGGGCGACCCGGT
CGGTCCTGCGACCCTCTCGGCCCGGCTCGGCGCCTCGGCGGGAGCCATGACCTCGCTGACCCAGCGCAGCTCCGGCCTGGTGCAGCGGCG
CACCGAGGCCTCCCGCAACGCCGCCGACAAGGAGCGGGCGGCGGGCGGCGGCGCCGGCAGCAGCGAGGACGACGCGCAGAGCCGCCGCGA
CGAGCAGGACGACGACGACAAGGGCGACTCCAAGGAAACGCGGCTGACCCTGATGGAGGAAGTGCTCCTGCTGGGCCTCAAGGACCGCGA
GGTGAGAAGCGCCACTGCTTTGATGTCAACTATAATTCAAGTTACATGTATGAGAAAGAGAGTGAGCTCATACAGACCCGCATGATGGAC
CAAGCCATCAATAACGCCATCAGCTATCTTGGCGCCGAAGCCCTGCGCCCCTTGGTCCAGACACCGCCTGCTCCCACCTCGGAGATGGTT
CCAGTTATCAGCAGCATGTATCCCATAGCCCTCACCCGGGCTGAGATGTCAAACGGTGCCCCTCAAGAGCTGGAAAAGAAAAGCATCCAC
CTTCCAGAGAAGAGCGTGCCTTCTGAGAGAGGCCTCTCTCCCAACAATAGTGGCCACGACTCCACGGACACTGACAGCAACCATGAAGAA
CGCCAGAATCACATCTATCAGCAAAATCACATGGTCCTGTCTCGGGCCCGCAATGGGATGCCACTTCTGAAGGAGGTTCCCCGCTCTTAC
GAACTCCTCAAGCCCCCGCCCATCTGCCCAAGAGACTCCGTCAAAGTGATCAACAAGGAAGGGGAGGTGATGGATGTGTATCGGTGTGAC
CACTGCCGCGTCCTCTTCCTGGACTATGTGATGTTCACGATTCACATGGGCTGCCACGGCTTCCGTGACCCTTTCGAGTGTAACATGTGT

>33968_33968_6_GOLPH3-IKZF3_GOLPH3_chr5_32173916_ENST00000265070_IKZF3_chr17_37922746_ENST00000350532_length(amino acids)=375AA_BP=89
MPRRRPASPLRPDLFPHDCPRPCCRRTSPRRPDLTRKPGSEAARGGGGRPGRSCDPLGPARRLGGSHDLADPAQLRPGAAAHRGLPQRRR
QGAGGGRRRRQQRGRRAEPPRRAGRRRQGRLQGNAADPDGGSAPAGPQGPRGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISY
LGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQN
HMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYE

--------------------------------------------------------------
>33968_33968_7_GOLPH3-IKZF3_GOLPH3_chr5_32173916_ENST00000265070_IKZF3_chr17_37922746_ENST00000351680_length(transcript)=1245nt_BP=541nt
ACATCCTCCGGTGACGTCAGCCGGGGCCGCCATATTGGAAAGGCGCCGCCGCCGCCTCCGCCTTGGAGCTCGGGGTGTTTCGGGGACTGC
GGCCACAGGCAGGAAGGCGCTCCTCTCCTGCCCCGCCGACGCCCGGCCAGCCCGCTTCGCCCTGACCTGTTTCCTCATGACTGCCCCCGG
CCCTGCTGCCGACGGACGTCGCCCCGGCGTCCGGATTTAACACGGAAACCCGGATCGGAGGCCGCGCGGGGAGGAGGAGGGCGACCCGGT
CGGTCCTGCGACCCTCTCGGCCCGGCTCGGCGCCTCGGCGGGAGCCATGACCTCGCTGACCCAGCGCAGCTCCGGCCTGGTGCAGCGGCG
CACCGAGGCCTCCCGCAACGCCGCCGACAAGGAGCGGGCGGCGGGCGGCGGCGCCGGCAGCAGCGAGGACGACGCGCAGAGCCGCCGCGA
CGAGCAGGACGACGACGACAAGGGCGACTCCAAGGAAACGCGGCTGACCCTGATGGAGGAAGTGCTCCTGCTGGGCCTCAAGGACCGCGA
GGTGAGAAGCGCCACTGCTTTGATGTCAACTATAATTCAAGTTACATGTATGAGAAAGAGAGTGAGCTCATACAGACCCGCATGATGGAC
CAAGCCATCAATAACGCCATCAGCTATCTTGGCGCCGAAGCCCTGCGCCCCTTGGTCCAGACACCGCCTGCTCCCACCTCGGAGATGGTT
CCAGTTATCAGCAGCATGTATCCCATAGCCCTCACCCGGGCTGAGATGTCAAACGGTGCCCCTCAAGAGCTGGAAAAGAAAAGCATCCAC
CTTCCAGAGAAGAGCGTGCCTTCTGAGAGAGGCCTCTCTCCCAACAATAGTGGCCACGACTCCACGGACACTGACAGCAACCATGAAGAA
CGCCAGAATCACATCTATCAGCAAAATCACATGGTCCTGTCTCGGGCCCGCAATGGGATGCCACTTCTGAAGGAGGTTCCCCGCTCTTAC
GAACTCCTCAAGCCCCCGCCCATCTGCCCAAGAGACTCCGTCAAAGTGATCAACAAGGAAGGGGAGGTGATGGATGTGTATCGGTGTGAC
CACTGCCGCGTCCTCTTCCTGGACTATGTGATGTTCACGATTCACATGGGCTGCCACGGCTTCCGTGACCCTTTCGAGTGTAACATGTGT

>33968_33968_7_GOLPH3-IKZF3_GOLPH3_chr5_32173916_ENST00000265070_IKZF3_chr17_37922746_ENST00000351680_length(amino acids)=375AA_BP=89
MPRRRPASPLRPDLFPHDCPRPCCRRTSPRRPDLTRKPGSEAARGGGGRPGRSCDPLGPARRLGGSHDLADPAQLRPGAAAHRGLPQRRR
QGAGGGRRRRQQRGRRAEPPRRAGRRRQGRLQGNAADPDGGSAPAGPQGPRGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISY
LGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQN
HMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYE

--------------------------------------------------------------
>33968_33968_8_GOLPH3-IKZF3_GOLPH3_chr5_32173916_ENST00000265070_IKZF3_chr17_37922746_ENST00000467757_length(transcript)=1245nt_BP=541nt
ACATCCTCCGGTGACGTCAGCCGGGGCCGCCATATTGGAAAGGCGCCGCCGCCGCCTCCGCCTTGGAGCTCGGGGTGTTTCGGGGACTGC
GGCCACAGGCAGGAAGGCGCTCCTCTCCTGCCCCGCCGACGCCCGGCCAGCCCGCTTCGCCCTGACCTGTTTCCTCATGACTGCCCCCGG
CCCTGCTGCCGACGGACGTCGCCCCGGCGTCCGGATTTAACACGGAAACCCGGATCGGAGGCCGCGCGGGGAGGAGGAGGGCGACCCGGT
CGGTCCTGCGACCCTCTCGGCCCGGCTCGGCGCCTCGGCGGGAGCCATGACCTCGCTGACCCAGCGCAGCTCCGGCCTGGTGCAGCGGCG
CACCGAGGCCTCCCGCAACGCCGCCGACAAGGAGCGGGCGGCGGGCGGCGGCGCCGGCAGCAGCGAGGACGACGCGCAGAGCCGCCGCGA
CGAGCAGGACGACGACGACAAGGGCGACTCCAAGGAAACGCGGCTGACCCTGATGGAGGAAGTGCTCCTGCTGGGCCTCAAGGACCGCGA
GGTGAGAAGCGCCACTGCTTTGATGTCAACTATAATTCAAGTTACATGTATGAGAAAGAGAGTGAGCTCATACAGACCCGCATGATGGAC
CAAGCCATCAATAACGCCATCAGCTATCTTGGCGCCGAAGCCCTGCGCCCCTTGGTCCAGACACCGCCTGCTCCCACCTCGGAGATGGTT
CCAGTTATCAGCAGCATGTATCCCATAGCCCTCACCCGGGCTGAGATGTCAAACGGTGCCCCTCAAGAGCTGGAAAAGAAAAGCATCCAC
CTTCCAGAGAAGAGCGTGCCTTCTGAGAGAGGCCTCTCTCCCAACAATAGTGGCCACGACTCCACGGACACTGACAGCAACCATGAAGAA
CGCCAGAATCACATCTATCAGCAAAATCACATGGTCCTGTCTCGGGCCCGCAATGGGATGCCACTTCTGAAGGAGGTTCCCCGCTCTTAC
GAACTCCTCAAGCCCCCGCCCATCTGCCCAAGAGACTCCGTCAAAGTGATCAACAAGGAAGGGGAGGTGATGGATGTGTATCGGTGTGAC
CACTGCCGCGTCCTCTTCCTGGACTATGTGATGTTCACGATTCACATGGGCTGCCACGGCTTCCGTGACCCTTTCGAGTGTAACATGTGT

>33968_33968_8_GOLPH3-IKZF3_GOLPH3_chr5_32173916_ENST00000265070_IKZF3_chr17_37922746_ENST00000467757_length(amino acids)=375AA_BP=89
MPRRRPASPLRPDLFPHDCPRPCCRRTSPRRPDLTRKPGSEAARGGGGRPGRSCDPLGPARRLGGSHDLADPAQLRPGAAAHRGLPQRRR
QGAGGGRRRRQQRGRRAEPPRRAGRRRQGRLQGNAADPDGGSAPAGPQGPRGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISY
LGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQN
HMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYE

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Fusion Gene PPI Analysis for GOLPH3-IKZF3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GOLPH3-IKZF3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GOLPH3-IKZF3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource