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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GORAB-DST (FusionGDB2 ID:34015)

Fusion Gene Summary for GORAB-DST

check button Fusion gene summary
Fusion gene informationFusion gene name: GORAB-DST
Fusion gene ID: 34015
HgeneTgene
Gene symbol

GORAB

DST

Gene ID

92344

667

Gene namegolgin, RAB6 interactingdystonin
SynonymsGO|NTKLBP1|SCYL1BP1BP240|BPA|BPAG1|CATX-15|CATX15|D6S1101|DMH|DT|EBSB2|HSAN6|MACF2
Cytomap

1q24.2

6p12.1

Type of geneprotein-codingprotein-coding
DescriptionRAB6-interacting golginN-terminal kinase-like-binding protein 1NTKL-binding protein 1SCY1-like 1-binding protein 1SCYL1-binding protein 1dystoninbullous pemphigoid antigen 1dystonia musculorum proteinhemidesmosomal plaque proteintrabeculin-beta
Modification date2020031320200313
UniProtAcc

Q5T7V8

Q6XUX3

Ensembl transtripts involved in fusion geneENST00000367763, ENST00000367762, 
ENST00000465717, 		ENST00000244364, 
ENST00000312431, ENST00000361203, 
ENST00000370754, ENST00000370788, 
ENST00000446842, ENST00000340834, 
ENST00000370765, ENST00000518935, 
ENST00000370769, ENST00000421834, 
Fusion gene scores* DoF score1 X 1 X 1=117 X 18 X 8=2448
# samples 119
** MAII scorelog2(1/1*10)=3.32192809488736log2(19/2448*10)=-3.6875322343617
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GORAB [Title/Abstract] AND DST [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGORAB(170521415)-DST(56382351), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneDST

GO:0009611

response to wounding

19403692


check buttonFusion gene breakpoints across GORAB (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DST (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABG952262GORABchr1

170521415

-DSTchr6

56382351

+


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Fusion Gene ORF analysis for GORAB-DST

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000367763ENST00000244364GORABchr1

170521415

-DSTchr6

56382351

+
5CDS-3UTRENST00000367763ENST00000312431GORABchr1

170521415

-DSTchr6

56382351

+
5CDS-3UTRENST00000367763ENST00000361203GORABchr1

170521415

-DSTchr6

56382351

+
5CDS-3UTRENST00000367763ENST00000370754GORABchr1

170521415

-DSTchr6

56382351

+
5CDS-3UTRENST00000367763ENST00000370788GORABchr1

170521415

-DSTchr6

56382351

+
5CDS-3UTRENST00000367763ENST00000446842GORABchr1

170521415

-DSTchr6

56382351

+
5CDS-5UTRENST00000367763ENST00000340834GORABchr1

170521415

-DSTchr6

56382351

+
5CDS-intronENST00000367763ENST00000370765GORABchr1

170521415

-DSTchr6

56382351

+
5CDS-intronENST00000367763ENST00000518935GORABchr1

170521415

-DSTchr6

56382351

+
In-frameENST00000367763ENST00000370769GORABchr1

170521415

-DSTchr6

56382351

+
In-frameENST00000367763ENST00000421834GORABchr1

170521415

-DSTchr6

56382351

+
intron-3CDSENST00000367762ENST00000370769GORABchr1

170521415

-DSTchr6

56382351

+
intron-3CDSENST00000367762ENST00000421834GORABchr1

170521415

-DSTchr6

56382351

+
intron-3CDSENST00000465717ENST00000370769GORABchr1

170521415

-DSTchr6

56382351

+
intron-3CDSENST00000465717ENST00000421834GORABchr1

170521415

-DSTchr6

56382351

+
intron-3UTRENST00000367762ENST00000244364GORABchr1

170521415

-DSTchr6

56382351

+
intron-3UTRENST00000367762ENST00000312431GORABchr1

170521415

-DSTchr6

56382351

+
intron-3UTRENST00000367762ENST00000361203GORABchr1

170521415

-DSTchr6

56382351

+
intron-3UTRENST00000367762ENST00000370754GORABchr1

170521415

-DSTchr6

56382351

+
intron-3UTRENST00000367762ENST00000370788GORABchr1

170521415

-DSTchr6

56382351

+
intron-3UTRENST00000367762ENST00000446842GORABchr1

170521415

-DSTchr6

56382351

+
intron-3UTRENST00000465717ENST00000244364GORABchr1

170521415

-DSTchr6

56382351

+
intron-3UTRENST00000465717ENST00000312431GORABchr1

170521415

-DSTchr6

56382351

+
intron-3UTRENST00000465717ENST00000361203GORABchr1

170521415

-DSTchr6

56382351

+
intron-3UTRENST00000465717ENST00000370754GORABchr1

170521415

-DSTchr6

56382351

+
intron-3UTRENST00000465717ENST00000370788GORABchr1

170521415

-DSTchr6

56382351

+
intron-3UTRENST00000465717ENST00000446842GORABchr1

170521415

-DSTchr6

56382351

+
intron-5UTRENST00000367762ENST00000340834GORABchr1

170521415

-DSTchr6

56382351

+
intron-5UTRENST00000465717ENST00000340834GORABchr1

170521415

-DSTchr6

56382351

+
intron-intronENST00000367762ENST00000370765GORABchr1

170521415

-DSTchr6

56382351

+
intron-intronENST00000367762ENST00000518935GORABchr1

170521415

-DSTchr6

56382351

+
intron-intronENST00000465717ENST00000370765GORABchr1

170521415

-DSTchr6

56382351

+
intron-intronENST00000465717ENST00000518935GORABchr1

170521415

-DSTchr6

56382351

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000367763GORABchr1170521415-ENST00000421834DSTchr656382351+8014192953007060586
ENST00000367763GORABchr1170521415-ENST00000370769DSTchr656382351+8095192953817141586

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000367763ENST00000421834GORABchr1170521415-DSTchr656382351+0.00172120.99827886
ENST00000367763ENST00000370769GORABchr1170521415-DSTchr656382351+0.0017650320.998235

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Fusion Genomic Features for GORAB-DST


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for GORAB-DST


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:170521415/chr6:56382351)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GORAB

Q5T7V8

DST

Q6XUX3

FUNCTION: Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation (PubMed:23862974, PubMed:28157540). Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death (PubMed:15178406). In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types (PubMed:28157540). {ECO:0000269|PubMed:15178406, ECO:0000269|PubMed:23862974, ECO:0000269|PubMed:28157540}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDSTchr1:170521415chr6:56382351ENST000002443640847210_722105172.0Calcium binding1
TgeneDSTchr1:170521415chr6:56382351ENST000002443640847246_725705172.0Calcium binding2
TgeneDSTchr1:170521415chr6:56382351ENST000003707650247210_722102650.0Calcium binding1
TgeneDSTchr1:170521415chr6:56382351ENST000003707650247246_725702650.0Calcium binding2
TgeneDSTchr1:170521415chr6:56382351ENST000002443640842394_243105172.0Compositional biasNote=Asp-rich
TgeneDSTchr1:170521415chr6:56382351ENST000002443640842592_259905172.0Compositional biasNote=Poly-Asp
TgeneDSTchr1:170521415chr6:56382351ENST000003707650242394_243102650.0Compositional biasNote=Asp-rich
TgeneDSTchr1:170521415chr6:56382351ENST000003707650242592_259902650.0Compositional biasNote=Poly-Asp
TgeneDSTchr1:170521415chr6:56382351ENST00000244364084151_25505172.0DomainCalponin-homology (CH) 2
TgeneDSTchr1:170521415chr6:56382351ENST0000024436408435_13805172.0DomainCalponin-homology (CH) 1
TgeneDSTchr1:170521415chr6:56382351ENST000002443640847197_723205172.0DomainEF-hand 1
TgeneDSTchr1:170521415chr6:56382351ENST000002443640847233_726805172.0DomainEF-hand 2
TgeneDSTchr1:170521415chr6:56382351ENST000002443640847273_735105172.0DomainGAR
TgeneDSTchr1:170521415chr6:56382351ENST00000244364084887_94405172.0DomainSH3
TgeneDSTchr1:170521415chr6:56382351ENST00000370765024151_25502650.0DomainCalponin-homology (CH) 2
TgeneDSTchr1:170521415chr6:56382351ENST0000037076502435_13802650.0DomainCalponin-homology (CH) 1
TgeneDSTchr1:170521415chr6:56382351ENST000003707650247197_723202650.0DomainEF-hand 1
TgeneDSTchr1:170521415chr6:56382351ENST000003707650247233_726802650.0DomainEF-hand 2
TgeneDSTchr1:170521415chr6:56382351ENST000003707650247273_735102650.0DomainGAR
TgeneDSTchr1:170521415chr6:56382351ENST00000370765024887_94402650.0DomainSH3
TgeneDSTchr1:170521415chr6:56382351ENST000002443640841383_138905172.0MotifNuclear localization signal%3B in isoform 6
TgeneDSTchr1:170521415chr6:56382351ENST000002443640847550_755305172.0MotifNote=Microtubule tip localization signal
TgeneDSTchr1:170521415chr6:56382351ENST000003707650241383_138902650.0MotifNuclear localization signal%3B in isoform 6
TgeneDSTchr1:170521415chr6:56382351ENST000003707650247550_755302650.0MotifNote=Microtubule tip localization signal
TgeneDSTchr1:170521415chr6:56382351ENST0000024436408435_25205172.0RegionNote=Actin-binding
TgeneDSTchr1:170521415chr6:56382351ENST0000037076502435_25202650.0RegionNote=Actin-binding
TgeneDSTchr1:170521415chr6:56382351ENST000002443640841293_142205172.0RepeatNote=Spectrin 3
TgeneDSTchr1:170521415chr6:56382351ENST000002443640841440_154005172.0RepeatNote=Spectrin 4
TgeneDSTchr1:170521415chr6:56382351ENST000002443640841584_162605172.0RepeatNote=Plectin 1
TgeneDSTchr1:170521415chr6:56382351ENST000002443640841660_170305172.0RepeatNote=Plectin 2
TgeneDSTchr1:170521415chr6:56382351ENST000002443640841774_181705172.0RepeatNote=Plectin 3
TgeneDSTchr1:170521415chr6:56382351ENST000002443640841818_185505172.0RepeatNote=Plectin 4
TgeneDSTchr1:170521415chr6:56382351ENST000002443640841856_189105172.0RepeatNote=Plectin 5
TgeneDSTchr1:170521415chr6:56382351ENST000002443640843395_350105172.0RepeatNote=Spectrin 5
TgeneDSTchr1:170521415chr6:56382351ENST000002443640843643_375205172.0RepeatNote=Spectrin 6
TgeneDSTchr1:170521415chr6:56382351ENST000002443640843926_404005172.0RepeatNote=Spectrin 7
TgeneDSTchr1:170521415chr6:56382351ENST000002443640844047_415305172.0RepeatNote=Spectrin 8
TgeneDSTchr1:170521415chr6:56382351ENST000002443640844160_425905172.0RepeatNote=Spectrin 9
TgeneDSTchr1:170521415chr6:56382351ENST000002443640844269_436805172.0RepeatNote=Spectrin 10
TgeneDSTchr1:170521415chr6:56382351ENST000002443640844516_462105172.0RepeatNote=Spectrin 11
TgeneDSTchr1:170521415chr6:56382351ENST000002443640844628_473205172.0RepeatNote=Spectrin 12
TgeneDSTchr1:170521415chr6:56382351ENST000002443640844742_484205172.0RepeatNote=Spectrin 13
TgeneDSTchr1:170521415chr6:56382351ENST000002443640844849_495105172.0RepeatNote=Spectrin 14
TgeneDSTchr1:170521415chr6:56382351ENST000002443640844958_505805172.0RepeatNote=Spectrin 15
TgeneDSTchr1:170521415chr6:56382351ENST000002443640845068_516705172.0RepeatNote=Spectrin 16
TgeneDSTchr1:170521415chr6:56382351ENST000002443640845174_527705172.0RepeatNote=Spectrin 17
TgeneDSTchr1:170521415chr6:56382351ENST000002443640845284_538805172.0RepeatNote=Spectrin 18
TgeneDSTchr1:170521415chr6:56382351ENST000002443640845395_549705172.0RepeatNote=Spectrin 19
TgeneDSTchr1:170521415chr6:56382351ENST000002443640845504_571505172.0RepeatNote=Spectrin 20
TgeneDSTchr1:170521415chr6:56382351ENST000002443640845831_593305172.0RepeatNote=Spectrin 21
TgeneDSTchr1:170521415chr6:56382351ENST000002443640845941_604105172.0RepeatNote=Spectrin 22
TgeneDSTchr1:170521415chr6:56382351ENST00000244364084602_69905172.0RepeatNote=Spectrin 1
TgeneDSTchr1:170521415chr6:56382351ENST000002443640846048_615405172.0RepeatNote=Spectrin 23
TgeneDSTchr1:170521415chr6:56382351ENST000002443640846161_626305172.0RepeatNote=Spectrin 24
TgeneDSTchr1:170521415chr6:56382351ENST000002443640846270_637305172.0RepeatNote=Spectrin 25
TgeneDSTchr1:170521415chr6:56382351ENST000002443640846380_648205172.0RepeatNote=Spectrin 26
TgeneDSTchr1:170521415chr6:56382351ENST000002443640846489_659105172.0RepeatNote=Spectrin 27
TgeneDSTchr1:170521415chr6:56382351ENST000002443640846598_670005172.0RepeatNote=Spectrin 28
TgeneDSTchr1:170521415chr6:56382351ENST000002443640846707_681005172.0RepeatNote=Spectrin 29
TgeneDSTchr1:170521415chr6:56382351ENST000002443640846817_691805172.0RepeatNote=Spectrin 30
TgeneDSTchr1:170521415chr6:56382351ENST000002443640846925_702705172.0RepeatNote=Spectrin 31
TgeneDSTchr1:170521415chr6:56382351ENST00000244364084701_80205172.0RepeatNote=Spectrin 2
TgeneDSTchr1:170521415chr6:56382351ENST000002443640847037_716705172.0RepeatNote=Spectrin 32
TgeneDSTchr1:170521415chr6:56382351ENST000003707650241293_142202650.0RepeatNote=Spectrin 3
TgeneDSTchr1:170521415chr6:56382351ENST000003707650241440_154002650.0RepeatNote=Spectrin 4
TgeneDSTchr1:170521415chr6:56382351ENST000003707650241584_162602650.0RepeatNote=Plectin 1
TgeneDSTchr1:170521415chr6:56382351ENST000003707650241660_170302650.0RepeatNote=Plectin 2
TgeneDSTchr1:170521415chr6:56382351ENST000003707650241774_181702650.0RepeatNote=Plectin 3
TgeneDSTchr1:170521415chr6:56382351ENST000003707650241818_185502650.0RepeatNote=Plectin 4
TgeneDSTchr1:170521415chr6:56382351ENST000003707650241856_189102650.0RepeatNote=Plectin 5
TgeneDSTchr1:170521415chr6:56382351ENST000003707650243395_350102650.0RepeatNote=Spectrin 5
TgeneDSTchr1:170521415chr6:56382351ENST000003707650243643_375202650.0RepeatNote=Spectrin 6
TgeneDSTchr1:170521415chr6:56382351ENST000003707650243926_404002650.0RepeatNote=Spectrin 7
TgeneDSTchr1:170521415chr6:56382351ENST000003707650244047_415302650.0RepeatNote=Spectrin 8
TgeneDSTchr1:170521415chr6:56382351ENST000003707650244160_425902650.0RepeatNote=Spectrin 9
TgeneDSTchr1:170521415chr6:56382351ENST000003707650244269_436802650.0RepeatNote=Spectrin 10
TgeneDSTchr1:170521415chr6:56382351ENST000003707650244516_462102650.0RepeatNote=Spectrin 11
TgeneDSTchr1:170521415chr6:56382351ENST000003707650244628_473202650.0RepeatNote=Spectrin 12
TgeneDSTchr1:170521415chr6:56382351ENST000003707650244742_484202650.0RepeatNote=Spectrin 13
TgeneDSTchr1:170521415chr6:56382351ENST000003707650244849_495102650.0RepeatNote=Spectrin 14
TgeneDSTchr1:170521415chr6:56382351ENST000003707650244958_505802650.0RepeatNote=Spectrin 15
TgeneDSTchr1:170521415chr6:56382351ENST000003707650245068_516702650.0RepeatNote=Spectrin 16
TgeneDSTchr1:170521415chr6:56382351ENST000003707650245174_527702650.0RepeatNote=Spectrin 17
TgeneDSTchr1:170521415chr6:56382351ENST000003707650245284_538802650.0RepeatNote=Spectrin 18
TgeneDSTchr1:170521415chr6:56382351ENST000003707650245395_549702650.0RepeatNote=Spectrin 19
TgeneDSTchr1:170521415chr6:56382351ENST000003707650245504_571502650.0RepeatNote=Spectrin 20
TgeneDSTchr1:170521415chr6:56382351ENST000003707650245831_593302650.0RepeatNote=Spectrin 21
TgeneDSTchr1:170521415chr6:56382351ENST000003707650245941_604102650.0RepeatNote=Spectrin 22
TgeneDSTchr1:170521415chr6:56382351ENST00000370765024602_69902650.0RepeatNote=Spectrin 1
TgeneDSTchr1:170521415chr6:56382351ENST000003707650246048_615402650.0RepeatNote=Spectrin 23
TgeneDSTchr1:170521415chr6:56382351ENST000003707650246161_626302650.0RepeatNote=Spectrin 24
TgeneDSTchr1:170521415chr6:56382351ENST000003707650246270_637302650.0RepeatNote=Spectrin 25
TgeneDSTchr1:170521415chr6:56382351ENST000003707650246380_648202650.0RepeatNote=Spectrin 26
TgeneDSTchr1:170521415chr6:56382351ENST000003707650246489_659102650.0RepeatNote=Spectrin 27
TgeneDSTchr1:170521415chr6:56382351ENST000003707650246598_670002650.0RepeatNote=Spectrin 28
TgeneDSTchr1:170521415chr6:56382351ENST000003707650246707_681002650.0RepeatNote=Spectrin 29
TgeneDSTchr1:170521415chr6:56382351ENST000003707650246817_691802650.0RepeatNote=Spectrin 30
TgeneDSTchr1:170521415chr6:56382351ENST000003707650246925_702702650.0RepeatNote=Spectrin 31
TgeneDSTchr1:170521415chr6:56382351ENST00000370765024701_80202650.0RepeatNote=Spectrin 2
TgeneDSTchr1:170521415chr6:56382351ENST000003707650247037_716702650.0RepeatNote=Spectrin 32

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGORABchr1:170521415chr6:56382351ENST00000367762-14145_2970247.0Coiled coilOntology_term=ECO:0000255
HgeneGORABchr1:170521415chr6:56382351ENST00000367763-15145_2970395.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for GORAB-DST


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>34015_34015_1_GORAB-DST_GORAB_chr1_170521415_ENST00000367763_DST_chr6_56382351_ENST00000370769_length(transcript)=8095nt_BP=1929nt
GCGGCCGGGGAAAAACCCGGATGAGCTGGGCAGCAGTGTTGGCAGTCGCGGCTGCGAGATTTGGGCACTTTTGGGGGTGCCGGTGGCCCG
GGCCGATGGCGCAAGGTTGGGCAGGATTCTCTGAGGAGGAACTGAGGAGACTAAAGCAGACTAAAGATCCATTTGAACCACAGCGACGTC
TCCCCGCGAAGAAAAGTCGACAACAACTTCAGCGAGAAAAAGCCCTTGTAGAGCAAAGCCAAAAACTTGGGCTTCAAGATGGATCAACCT
CATTACTTCCAGAGCAGCTGCTTTCAGCACCAAAACAGAGAGTTAACGTTCAAAAACCACCTTTTTCTTCCCCTACTCTTCCGAGTCATT
TCACTCTCACCTCCCCCGTTGGTGATGGACAACCACAGGGCATTGAAAGTCAGCCAAAGGAACTGGGACTTGAGAATTCCCATGATGGTC
ACAACAATGTTGAGATTCTACCTCCAAAGCCAGATTGCAAATTGGAGAAAAAGAAAGTGGAATTGCAAGAAAAATCTCGTTGGGAAGTCC
TCCAACAAGAACAACGGCTAATGGAAGAGAAAAATAAACGTAAAAAAGCTCTTTTGGCTAAAGCTATTGCAGAAAGATCCAAAAGAACTC
AGGCAGAGACCATGAAACTAAAGCGGATCCAGAAGGAGTTGCAGGCTTTAGATGACATGGTGTCAGCTGACATTGGAATTCTCAGGAACC
GGATTGATCAGGCCAGCTTAGACTATTCATACGCTCGAGAGGCCATTTCAGCCTGCGGAGGAGAGTGTGACATTAGAATTTGCTAAAGAG
AACAGAAAGTGTCAAGAACAAGCTGTTTCCCCAAAGGTAGATGACCAGTGTGGAAATTCCAGTAGCATCCCCTTTCTTAGTCCAAACTGC
CCAAATCAAGAAGGTAATGACATTTCAGCTGCTTTGGCCACATGAAGTTCTGGTATTCTTTTGAGCTAATATGGTATTGAGTAAAGTATA
CTTTTTGCAGTAGATCATGCCCTGACCTCCAATAAAAACCTCTTTAAAACAATGCTGATTTTTGAATTCATGATTAGTTTTAGTAAATTA
ATAGGTTTGGCCATTCTAAAATCCAAAATTATGATAACTGTATTTCTAGGGGTATGTTTCACCTTGATTTTGGCCCGGTTCTTTCAGTGT
TCCGTTTACCCTTTTTACTGAAAGTAAGTGACTTAAAAGGATGGAAGAAAAACTACATGGTTGGAGTGTTTTTAGATCAGATAAATATAG
AAAAGTAAAATGGAAAATGATACTCAATACCTAGTTAAACTCATTTCACTTCTCCTGGGAGACGTATTAAGACTGGAAGTCCTATTTTAT
TTAATCAGTATCAGTAAAAAGACAAAAATTACAGTGTGAACAAGAGAAAAACAGGAATAGAAGAAAAAAGTTGCAGGTTGAATTATCTAT
CTGGATATTACTAGAGTTGTAAAACACAACTTGGAAACTGGAATTTATGTGAAGAACCAAACAACTTAAACCAGCATCACTTTTGTCTTC
AATTTGCCTTCCAGTGATTTTAGTTTACAACCTGCGTTTTGTTATTTGAAACACACACACTTATATATAAACACATGTAATTTTACTATT
TTATTGTCTTTCCTTTAATCGATGAATTGATTAAATTTAGACAATTAAAACATTTCTAAAGTGAGACTGAAAATAATATAGAAAATCTCA
TTGCTACTTGTGATTATCAAAAAAAGTATGTATTTTCTTTCTAAAGTTATCTATAAATATGTTTTTGATATGTTGGACATGAATTACCCT
GTCATGAAGCGTTTAAATTGTTAAAATGCTGATTTTCTTATTAGTTTGTTAATTGCCTGTTACTAGTACTTGACCAATACATTGTGCTAT
ATGTAAATGTGTAAATAAATATTGTAATTTTCTCACAAAATTCCAAGAAGACTCCCAGCCGACCAGGAAGTCGAGCTGGAAGCAAAGCTG
GCAGCAGGGCCAGCAGCCGCCGAGGCAGTGATGCATCAGACTTTGACATTTCAGAAATCCAGTCCGTGTGCTCAGATGTGGAAACTGTCC
CCCAGACACACAGACCTACACCCCGAGCAGGTTCTCGGCCATCCACAGCGAAGCCTTCAAAAATCCCCACGCCCCAGAGGAAATCACCTG
CCAGCAAATTGGACAAGTCCTCAAAGAGATAGTGCAATTGGTTCTACCAAGGCCCTTCCTTGAGCATTTATTATTTAAGTTTGAACGATG
TAAAATATGGTGTAGAAATTCTTGTGAAATATTGCAAGAGGCGAGTTTAAAATTCTGCAGATGGCCTTATTTGTGTATTTGTCTTTTTAT
TTTATCTGTATAATTTTTTTTGTCAGATATTCTGGGGTTAAAGTCACATCATATGTGAGGAGGAAAAGTTTAACATGAACTAACATTTCT
GCACTGTAACGTGCCGGGCACACACTAAACTCAGTTACTGTACCTACAGGTAAGTCTACATCCTCTCTGACAGCCACAGCACTACATCAA
TCCCTGACGTTAGGGATACCTCATGACATTTTCCTGTTTTTATGGAAACTCTGAGAAGCTGAATGATACATGCAGGGGATATTTTTTGAG
ATGATTTAAATGTAAACCAAAAGATGGAAGACAAAAAGACAAACACACCCACACGCAGTCTTTGCAGTATCTGACAGAGAACTCACAGGA
AGTTACTTCAAGCACTTGCCAGTACTATGATATTCAAGTACCTTGCAGCATTTCTCTGCCATTGCTTTCAATGAGGCCAGAGGCATCCTG
GATATTAGACCTATTATACTGTAAGAATATAAGTATAAAGTGCGTTCATATACATGTGAGGTTTTCTTTTGCTTGAGTGGACAGTAGCAC
CTGTATCATTGAACTCATTTTGTATCAGAGCAATTTTGCTTGCAGAAAGCTATGAAATAAAACACGTCCCTTAACTGCATTGCTATGGAA
TTAATTTTTTTTCCCCAGGGAAAACTAGTGTATTTTTTTATGAGCAATATCAATTTGGAGTGACCAAAAGATACTTAAAAATGGGTTTAT
TTTGATTTCTCATCTGAAATAATCATGTTCTGGTATTATATCTATCTATATTTAATAAATATATACATTTTAATTTATTATGTGTACTCA
CATACTATAGAAAGATATTAGTATGCATTTAATAAAACATATTCACTTGAATATATGGGGAACGCCAATACAAGGAAGCAAGCTTCGACT
TCCAGGATATTTATCAGGGAAAGGCTTCCACTCTGGGGAGGACAGTGGCTTGATAACAACTGCAGCTGCCAGAGTCCGAACACAGTTTGC
TGCCAAAGGAAGGACAAACATGGAACTGCGTGAGAAGTTCATTTTAGCAGATGGTGCCAGCCAGGGTATGGCTGCTTTCCGACCCCGAGG
CCGAAGATCCCGGCCATCATCACGAGGCGCTTCACCCAACAGATCCACTTCTGTGTCCAGTCAGGCTGCGCAGGCGGCCTCCCCACAGGT
CCCTGCCACCACCACACCCAAGTTCATCATCATGGGAGTAAAATGTTACGTTCGGAATCAAACTCTTCAATTACTACTACTCAGCCTACT
ATAGTTTGGAGACTCCCAGCAACTGCGACTGGTCCGGATCCTGCGGAGTACTGTGATGGTTCGTGTTGGAGGTGGATGGATGGCACTTGA
TGAGTTCTTAGTGAAAAATGATCCTTGCAGGGGTGACAAGGCAGGTAGCTAAGTGTAAATGTGCAAAGCGATTTCAAGTTGAGCAGATTG
GTGATAATAAATACAGGGTAAGTTTTCAAAGTAATAGTTTCCAACCAGTCGCTTGGAGATGAGCGCAGTTGCAGACATCTTTGACAGAGA
TGGCGATGGATATATTGACTACTATGAATTTGTAGCAGCCCTTCACCCAAATAAAGATGCATATAAACCTATCACAGATGCCGACAAAAT
CGAAGATGAGCTGAGGGAATTTGCTAACTTTGATTTTGATATCTGGCGCAAAAAATACATGCGATGGATGAATCACAAGAAATCTCGAGT
GATGGACTTCTTCAGGAGAATTGATAAAGACCAGGATGGGAAAATAACGCGGCAGGAATTTATTGATGGAATTCTTTCCTCAAGAAAACG
CTTTCCAGCATCAAGCTTGTATCCCTCTGGGTCACAGACACAAATTGAAACCAAAAATCCTAGGGTAAACTTACTGGTGAGCAAATGGCA
GCAAGTCTGGCTCCTGGCGTTGGAAAGAAGGAGGAAACTCAATGATGCCTTGGACAGACTAGAGGAGACCTTCATGGAGGAAATGACCAG
AAAACAGCCTGATGTTGATAAAGTAACGAAGACCTATAAGAGGAGAGCTGCTGATCCTTCCTCATTACAATCCCATATTCCAGTCTTGGA
TAAGGGACGAGCAGGAAGTGCTGGCCTGGGCAAAGCAACATCAGCAGAGATTAGCAAGTGCTCTGGCTGGGCTTATTGCCAAACAGGAAT
TGTTGGAAGCTTTGCTGGCTTGGTTGCAATGGGCTGAAACTACACTTACTGATAAGGATAAAGAAGTCATCCCCCAGGAGATCGAAGAGG
TGAAAGCACTCATTGCAGAACACCAGGAATTCATGAAGAAACTGGAAGAAAAGAGAGCTGAACTAAATAAAGCCACCACTATGGGCGACA
CCGTTTTGGCTATCTGCCACCCCGACTCCATCACTACCATTAAGCACTGGATAACAATCATCCGGGCGAGGTTTGAGGAGGCAGAGGAAT
TCCACTCGGTGGTACATGCCCTCTTGGAGTGGCTGGCTGAGGCGGAGCAAACCCTGCGTTTCCATGGTGTCCTCCCAGATGATGAGGATG
CTCTCCGGACTCTCATTGATCAGCATAAAGCCTTCCAAAAAGAGTTGGGGAAGAGGACCAGCAGTGTGCAGGCCCTGAAGCGCTCAGCCC
GAGAACTCATAGAAGGCAGTCGGGATGACTCCTCCTGGGTCAAGGTCCAGATGCAGGAATTAAGCACACGCTGGGAGACCGTGTGTGCAC
TTTCTATATCAAAGCAAACACGGTTAGAAGCAGCCCTGCGTCAGACAAAACAAATTGGAGGAAGCCCTGTTATTTTCTGGACAATTCACA
GATGCCCTACAGGCTCTCATTGATTGGTTATATAGAGTTGAACCCCAGCTGGCAGAAGACCAGCCTGTTCATGGAGACATTGATTTGGTG
ATGAATCTGATCGATAATCACAAGGAGTTTCAGAAATCACTCGGAGCCAAGCATTCTGTCTACGACACCACCAACAGGACTGGACGTTCT
CTGAAGGAGAAAACCTCCCTGGCTGATGACAACCTGAAACTGGATGACATGCTGAGTGAACTCAGAGACAAATGGGATACCATATGTGGA
AAATCTGTGGAAAGTTCCATGAAGCTTGGAGTAAACTTATGGAGTGGCTAGAAGAGTCAGAAAAGTCTTTGGATTCTGAACTGGAAATCG
CAAATGATCCAGACAAAATAAAAACACAACTTGCACAACATAAGGTTTTTGCCAATGAAGTAAATTCTCATCGTGAGCAGATAATAGAGC
TGGACAAAACTGGAACCCACCTAAAATATTTTAGTCAGAAACAAGATGTTGTTCTAATCAAGAATCTACTTATCAGTGTACAAAGTCGAT
GGGAAAAAGTGGTTCAACGGTTGGTAGAGAGAGGAAGATCTTTGGATGATGCAAGGAAGAGAGCCAAGCAGACTAAACTGGAAGAGGCTC
TCAACTTGGCAATGGAGTTCCACAATTCTCTCCAAGACTTCATCAACTGGCTTACTCAGGCTGAACAGACCCTAAATGTAGCTTCTCGGC
CAAGTCTCATCTTGGACACAGTCTTATTTCAAATTGACGAACACAAGGAAGTCTGTGCTGCCTTTGAAGCTAAAGAAGAAACATATAAGA
GTCTGATGCAGAAAGGCCAGCAGATGCTTGCAAGATGCCCAAAATCTGCAGAGACAAATATTGACCAAGACATAAATAACTTGAAAGAAA
AATGGGAATCGGTGGAAACCAAACTCAATGAAAGGAAAGCCAAAGGGTTCCATGGCGAAATTGAGGATTTGCAGCAGTGGCTGACTGACA
CGGAGCGTCATCTGTTGGCATCTAAACCGCTGGGAGGTTTACCGGAAACAGCCAAGGAGCAGCTTAATGTCCATATGGTGCTCCAAAATG
ATGTATTAGCCCATCAGTCCACAGTGGAAGCCGTTAATAAAGCAGGAAATGATCTAATTGAATCAAGTGCAGGAGAAGAAGCAAGCAACC
TTCAGAACAAGCTAGAGGTTTTAAATCAACGCTGGCAAAATGTTTTGGAAAAAACAGAACAAAGGAAGCAGCAGCTGGATGGTGCCTTGC
GCCAGCATAAACTGGAGGGTGCTCTATTAGCCTTGGGTCAGTTCCAACATGCCCTGGATGAGCTCCTGGCATGGCTGACACACACCGAGG
GCTTGCTAAGTGAGCAGAAACCTGTTGGAGGAGACCCTAAAGCCATTGAAATTGAACTTGCCAAGCATCATCAATTTAAGTCTGAGGCCT
ATCAACAGCAGATAGAAATGGAAAGACTGAATCATCAAGCAGAGCTTTTGCTAAAGAAAGTAACAGAAGAGAGTGACAAACACACTGTTC
AAGACCCATTAATGGAACTGAAATTGATATGGGATAGCCTGGAGGAGAGAATCATCAACAGACAGGCGGTATTTGACTGGGTAGATATTG
CAGGTGGTAAATTAGCTTCAATGTCTCCAATTGGAACAGATCTCGAAACTGTCAAGCAGCAGATTGAAGAGCTAAAGTTAAATTCAGCAT
GGGATTCTCTAAATAAAGCTTGGAAAGACCGGATTGACAAACTTGAGGAGGCAATGCAGGCTGCCGTTCAGTACCAGGATGGACTGCAGA
CCATAAGGGAAGAAATAGATGGACTACAGGAGGAGCTGGATATAGTTATTAACCTAGGTTCTGAACTCATTGCGGCATGTGGGGAGCCTG
ATAAACCCATTGTCAAGAAGAGTATAGATGAGCTGTTCAGGATAAGCTTGACCAAATGGTTTTCATTTGGGAGAACATACACACACTGGT
GGAAGAGAGGGAAGCCAAACTACTGGATGTGATGGAGCTAGCAGAAAAGTTCTGGTGTGATCACATGTCATTGATAGTTACCATTAAAGA
TACTCAAGATTTCATCCGGGACCTGGAAGATCCTGGAATTGATCCTTCAGTAGTAAAACAACAGCAAGAAGCAGCAGAGTTCCATGACAA
GATAGATCAGATCCTTGAGAGCCTGGAACGCATCGTGGAACGTCTGAGGCAGCCACCCTCTATCTCTGCAGAGGTTGAGAAGATCAAGGA
ACAGATCAGTGAAAATAAGAATGTGTCAGTAGACATGGAAAAGCTACAGCCGTTGTATGAAACTCTTAAACAGAGGGGAGAGGAAATGAT
TGCTAGATCTGGGGGGACTGATAAAGACATATCTGCCAAAGCAACTGCGTGAGTTGATAGCTGAACACAAGCCTCATATAGATAAGATGA
ACAAAACTGGGCCACAGTTACTGGAATTGAGCCCTGGGGAAGGCTTTTCTATCCAAGAGAAGTATGTGGCAGCCGACACCCTTTACAGTC
AAATTAAAGAAGATGTCAAAAAGCGTGCTGTGGCACTGGATGAAGCCATTTCTCAATCAACTCAGAAAAAACTGGACAAGGTACTGAAGA
ACTATGATACCATCTGCCAGATTAATTCAGAAAGGTATCTGCAGCTGGAACGGGCACAGTCCCTGGTTAACCAATTCTGGGAAACATATG
AAGAACTTTGGCCATGGCTGACAGAAACACAATCAATCATCTCTCAGCTTCCCGCCCCAGCCCTTGAATATGAAACTCTAAGGCAGCAGC
AGGAAGAACATCGGACATTCACCATGGAGATTTTGAGACACAAGGATATTATTGATGACCTTGTTAAATCTGGGCATAAAATCATGACCG

>34015_34015_1_GORAB-DST_GORAB_chr1_170521415_ENST00000367763_DST_chr6_56382351_ENST00000370769_length(amino acids)=586AA_BP=
MGYHMWKICGKFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLL
ISVQSRWEKVVQRLVERGRSLDDARKRAKQTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLFQIDEHKEVCAAFEA
KEETYKSLMQKGQQMLARCPKSAETNIDQDINNLKEKWESVETKLNERKAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNV
HMVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQHKLEGALLALGQFQHALDELLA
WLTHTEGLLSEQKPVGGDPKAIEIELAKHHQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDPLMELKLIWDSLEERIINRQAV
FDWVDIAGGKLASMSPIGTDLETVKQQIEELKLNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQTIREEIDGLQEELDIVINLGSELI

--------------------------------------------------------------
>34015_34015_2_GORAB-DST_GORAB_chr1_170521415_ENST00000367763_DST_chr6_56382351_ENST00000421834_length(transcript)=8014nt_BP=1929nt
GCGGCCGGGGAAAAACCCGGATGAGCTGGGCAGCAGTGTTGGCAGTCGCGGCTGCGAGATTTGGGCACTTTTGGGGGTGCCGGTGGCCCG
GGCCGATGGCGCAAGGTTGGGCAGGATTCTCTGAGGAGGAACTGAGGAGACTAAAGCAGACTAAAGATCCATTTGAACCACAGCGACGTC
TCCCCGCGAAGAAAAGTCGACAACAACTTCAGCGAGAAAAAGCCCTTGTAGAGCAAAGCCAAAAACTTGGGCTTCAAGATGGATCAACCT
CATTACTTCCAGAGCAGCTGCTTTCAGCACCAAAACAGAGAGTTAACGTTCAAAAACCACCTTTTTCTTCCCCTACTCTTCCGAGTCATT
TCACTCTCACCTCCCCCGTTGGTGATGGACAACCACAGGGCATTGAAAGTCAGCCAAAGGAACTGGGACTTGAGAATTCCCATGATGGTC
ACAACAATGTTGAGATTCTACCTCCAAAGCCAGATTGCAAATTGGAGAAAAAGAAAGTGGAATTGCAAGAAAAATCTCGTTGGGAAGTCC
TCCAACAAGAACAACGGCTAATGGAAGAGAAAAATAAACGTAAAAAAGCTCTTTTGGCTAAAGCTATTGCAGAAAGATCCAAAAGAACTC
AGGCAGAGACCATGAAACTAAAGCGGATCCAGAAGGAGTTGCAGGCTTTAGATGACATGGTGTCAGCTGACATTGGAATTCTCAGGAACC
GGATTGATCAGGCCAGCTTAGACTATTCATACGCTCGAGAGGCCATTTCAGCCTGCGGAGGAGAGTGTGACATTAGAATTTGCTAAAGAG
AACAGAAAGTGTCAAGAACAAGCTGTTTCCCCAAAGGTAGATGACCAGTGTGGAAATTCCAGTAGCATCCCCTTTCTTAGTCCAAACTGC
CCAAATCAAGAAGGTAATGACATTTCAGCTGCTTTGGCCACATGAAGTTCTGGTATTCTTTTGAGCTAATATGGTATTGAGTAAAGTATA
CTTTTTGCAGTAGATCATGCCCTGACCTCCAATAAAAACCTCTTTAAAACAATGCTGATTTTTGAATTCATGATTAGTTTTAGTAAATTA
ATAGGTTTGGCCATTCTAAAATCCAAAATTATGATAACTGTATTTCTAGGGGTATGTTTCACCTTGATTTTGGCCCGGTTCTTTCAGTGT
TCCGTTTACCCTTTTTACTGAAAGTAAGTGACTTAAAAGGATGGAAGAAAAACTACATGGTTGGAGTGTTTTTAGATCAGATAAATATAG
AAAAGTAAAATGGAAAATGATACTCAATACCTAGTTAAACTCATTTCACTTCTCCTGGGAGACGTATTAAGACTGGAAGTCCTATTTTAT
TTAATCAGTATCAGTAAAAAGACAAAAATTACAGTGTGAACAAGAGAAAAACAGGAATAGAAGAAAAAAGTTGCAGGTTGAATTATCTAT
CTGGATATTACTAGAGTTGTAAAACACAACTTGGAAACTGGAATTTATGTGAAGAACCAAACAACTTAAACCAGCATCACTTTTGTCTTC
AATTTGCCTTCCAGTGATTTTAGTTTACAACCTGCGTTTTGTTATTTGAAACACACACACTTATATATAAACACATGTAATTTTACTATT
TTATTGTCTTTCCTTTAATCGATGAATTGATTAAATTTAGACAATTAAAACATTTCTAAAGTGAGACTGAAAATAATATAGAAAATCTCA
TTGCTACTTGTGATTATCAAAAAAAGTATGTATTTTCTTTCTAAAGTTATCTATAAATATGTTTTTGATATGTTGGACATGAATTACCCT
GTCATGAAGCGTTTAAATTGTTAAAATGCTGATTTTCTTATTAGTTTGTTAATTGCCTGTTACTAGTACTTGACCAATACATTGTGCTAT
ATGTAAATGTGTAAATAAATATTGTAATTTTCTCACAAAATTCCAAGAAGACTCCCAGCCGACCAGGAAGTCGAGCTGGAAGCAAAGCTG
GCAGCAGGGCCAGCAGCCGCCGAGGCAGTGATGCATCAGACTTTGACATTTCAGAAATCCAGTCCGTGTGCTCAGATGTGGAAACTGTCC
CCCAGACACACAGACCTACACCCCGAGCAGGTTCTCGGCCATCCACAGCGAAGCCTTCAAAAATCCCCACGCCCCAGAGGAAATCACCTG
CCAGCAAATTGGACAAGTCCTCAAAGAGATAGTGCAATTGGTTCTACCAAGGCCCTTCCTTGAGCATTTATTATTTAAGTTTGAACGATG
TAAAATATGGTGTAGAAATTCTTGTGAAATATTGCAAGAGGCGAGTTTAAAATTCTGCAGATGGCCTTATTTGTGTATTTGTCTTTTTAT
TTTATCTGTATAATTTTTTTTGTCAGATATTCTGGGGTTAAAGTCACATCATATGTGAGGAGGAAAAGTTTAACATGAACTAACATTTCT
GCACTGTAACGTGCCGGGCACACACTAAACTCAGTTACTGTACCTACAGGTAAGTCTACATCCTCTCTGACAGCCACAGCACTACATCAA
TCCCTGACGTTAGGGATACCTCATGACATTTTCCTGTTTTTATGGAAACTCTGAGAAGCTGAATGATACATGCAGGGGATATTTTTTGAG
ATGATTTAAATGTAAACCAAAAGATGGAAGACAAAAAGACAAACACACCCACACGCAGTCTTTGCAGTATCTGACAGAGAACTCACAGGA
AGTTACTTCAAGCACTTGCCAGTACTATGATATTCAAGTACCTTGCAGCATTTCTCTGCCATTGCTTTCAATGAGGCCAGAGGCATCCTG
GATATTAGACCTATTATACTGTAAGAATATAAGTATAAAGTGCGTTCATATACATGTGAGGTTTTCTTTTGCTTGAGTGGACAGTAGCAC
CTGTATCATTGAACTCATTTTGTATCAGAGCAATTTTGCTTGCAGAAAGCTATGAAATAAAACACGTCCCTTAACTGCATTGCTATGGAA
TTAATTTTTTTTCCCCAGGGAAAACTAGTGTATTTTTTTATGAGCAATATCAATTTGGAGTGACCAAAAGATACTTAAAAATGGGTTTAT
TTTGATTTCTCATCTGAAATAATCATGTTCTGGTATTATATCTATCTATATTTAATAAATATATACATTTTAATTTATTATGTGTACTCA
CATACTATAGAAAGATATTAGTATGCATTTAATAAAACATATTCACTTGAATATATGGGGAACGCCAATACAAGGAAGCAAGCTTCGACT
TCCAGGATATTTATCAGGGAAAGGCTTCCACTCTGGGGAGGACAGTGGCTTGATAACAACTGCAGCTGCCAGAGTCCGAACACAGTTTGC
TGCCAAAGGAAGGACAAACATGGAACTGCGTGAGAAGTTCATTTTAGCAGATGGTGCCAGCCAGGGTATGGCTGCTTTCCGACCCCGAGG
CCGAAGATCCCGGCCATCATCACGAGGCGCTTCACCCAACAGATCCACTTCTGTGTCCAGTCAGGCTGCGCAGGCGGCCTCCCCACAGGT
CCCTGCCACCACCACACCCAAGTTCATCATCATGGGAGTAAAATGTTACGTTCGGAATCAAACTCTTCAATTACTACTACTCAGCCTACT
ATAGTTTGGAGACTCCCAGCAACTGCGACTGGTCCGGATCCTGCGGAGTACTGTGATGGTTCGTGTTGGAGGTGGATGGATGGCACTTGA
TGAGTTCTTAGTGAAAAATGATCCTTGCAGGGGTGACAAGGCAGGTAGCTAAGTGTAAATGTGCAAAGCGATTTCAAGTTGAGCAGATTG
GTGATAATAAATACAGGGTAAGTTTTCAAAGTAATAGTTTCCAACCAGTCGCTTGGAGATGAGCGCAGTTGCAGACATCTTTGACAGAGA
TGGCGATGGATATATTGACTACTATGAATTTGTAGCAGCCCTTCACCCAAATAAAGATGCATATAAACCTATCACAGATGCCGACAAAAT
CGAAGATGAGCTGAGGGAATTTGCTAACTTTGATTTTGATATCTGGCGCAAAAAATACATGCGATGGATGAATCACAAGAAATCTCGAGT
GATGGACTTCTTCAGGAGAATTGATAAAGACCAGGATGGGAAAATAACGCGGCAGGAATTTATTGATGGAATTCTTTCCTCAAGAAAACG
CTTTCCAGCATCAAGCTTGTATCCCTCTGGGTCACAGACACAAATTGAAACCAAAAATCCTAGGGTAAACTTACTGACCTTCATGGAGGA
AATGACCAGAAAACAGCCTGATGTTGATAAAGTAACGAAGACCTATAAGAGGAGAGCTGCTGATCCTTCCTCATTACAATCCCATATTCC
AGTCTTGGATAAGGGACGAGCAGGAAGTGCTGGCCTGGGCAAAGCAACATCAGCAGAGATTAGCAAGTGCTCTGGCTGGGCTTATTGCCA
AACAGGAATTGTTGGAAGCTTTGCTGGCTTGGTTGCAATGGGCTGAAACTACACTTACTGATAAGGATAAAGAAGTCATCCCCCAGGAGA
TCGAAGAGGTGAAAGCACTCATTGCAGAACACCAGGAATTCATGAAGAAACTGGAAGAAAAGAGAGCTGAACTAAATAAAGCCACCACTA
TGGGCGACACCGTTTTGGCTATCTGCCACCCCGACTCCATCACTACCATTAAGCACTGGATAACAATCATCCGGGCGAGGTTTGAGGAGG
CAGAGGAATTCCACTCGGTGGTACATGCCCTCTTGGAGTGGCTGGCTGAGGCGGAGCAAACCCTGCGTTTCCATGGTGTCCTCCCAGATG
ATGAGGATGCTCTCCGGACTCTCATTGATCAGCATAAAGCCTTCCAAAAAGAGTTGGGGAAGAGGACCAGCAGTGTGCAGGCCCTGAAGC
GCTCAGCCCGAGAACTCATAGAAGGCAGTCGGGATGACTCCTCCTGGGTCAAGGTCCAGATGCAGGAATTAAGCACACGCTGGGAGACCG
TGTGTGCACTTTCTATATCAAAGCAAACACGGTTAGAAGCAGCCCTGCGTCAGACAAAACAAATTGGAGGAAGCCCTGTTATTTTCTGGA
CAATTCACAGATGCCCTACAGGCTCTCATTGATTGGTTATATAGAGTTGAACCCCAGCTGGCAGAAGACCAGCCTGTTCATGGAGACATT
GATTTGGTGATGAATCTGATCGATAATCACAAGGAGTTTCAGAAATCACTCGGAGCCAAGCATTCTGTCTACGACACCACCAACAGGACT
GGACGTTCTCTGAAGGAGAAAACCTCCCTGGCTGATGACAACCTGAAACTGGATGACATGCTGAGTGAACTCAGAGACAAATGGGATACC
ATATGTGGAAAATCTGTGGAAAGTTCCATGAAGCTTGGAGTAAACTTATGGAGTGGCTAGAAGAGTCAGAAAAGTCTTTGGATTCTGAAC
TGGAAATCGCAAATGATCCAGACAAAATAAAAACACAACTTGCACAACATAAGGTTTTTGCCAATGAAGTAAATTCTCATCGTGAGCAGA
TAATAGAGCTGGACAAAACTGGAACCCACCTAAAATATTTTAGTCAGAAACAAGATGTTGTTCTAATCAAGAATCTACTTATCAGTGTAC
AAAGTCGATGGGAAAAAGTGGTTCAACGGTTGGTAGAGAGAGGAAGATCTTTGGATGATGCAAGGAAGAGAGCCAAGCAGACTAAACTGG
AAGAGGCTCTCAACTTGGCAATGGAGTTCCACAATTCTCTCCAAGACTTCATCAACTGGCTTACTCAGGCTGAACAGACCCTAAATGTAG
CTTCTCGGCCAAGTCTCATCTTGGACACAGTCTTATTTCAAATTGACGAACACAAGGAAGTCTGTGCTGCCTTTGAAGCTAAAGAAGAAA
CATATAAGAGTCTGATGCAGAAAGGCCAGCAGATGCTTGCAAGATGCCCAAAATCTGCAGAGACAAATATTGACCAAGACATAAATAACT
TGAAAGAAAAATGGGAATCGGTGGAAACCAAACTCAATGAAAGGAAAGCCAAAGGGTTCCATGGCGAAATTGAGGATTTGCAGCAGTGGC
TGACTGACACGGAGCGTCATCTGTTGGCATCTAAACCGCTGGGAGGTTTACCGGAAACAGCCAAGGAGCAGCTTAATGTCCATATGGTGC
TCCAAAATGATGTATTAGCCCATCAGTCCACAGTGGAAGCCGTTAATAAAGCAGGAAATGATCTAATTGAATCAAGTGCAGGAGAAGAAG
CAAGCAACCTTCAGAACAAGCTAGAGGTTTTAAATCAACGCTGGCAAAATGTTTTGGAAAAAACAGAACAAAGGAAGCAGCAGCTGGATG
GTGCCTTGCGCCAGCATAAACTGGAGGGTGCTCTATTAGCCTTGGGTCAGTTCCAACATGCCCTGGATGAGCTCCTGGCATGGCTGACAC
ACACCGAGGGCTTGCTAAGTGAGCAGAAACCTGTTGGAGGAGACCCTAAAGCCATTGAAATTGAACTTGCCAAGCATCATCAATTTAAGT
CTGAGGCCTATCAACAGCAGATAGAAATGGAAAGACTGAATCATCAAGCAGAGCTTTTGCTAAAGAAAGTAACAGAAGAGAGTGACAAAC
ACACTGTTCAAGACCCATTAATGGAACTGAAATTGATATGGGATAGCCTGGAGGAGAGAATCATCAACAGACAGGCGGTATTTGACTGGG
TAGATATTGCAGGTGGTAAATTAGCTTCAATGTCTCCAATTGGAACAGATCTCGAAACTGTCAAGCAGCAGATTGAAGAGCTAAAGTTAA
ATTCAGCATGGGATTCTCTAAATAAAGCTTGGAAAGACCGGATTGACAAACTTGAGGAGGCAATGCAGGCTGCCGTTCAGTACCAGGATG
GACTGCAGACCATAAGGGAAGAAATAGATGGACTACAGGAGGAGCTGGATATAGTTATTAACCTAGGTTCTGAACTCATTGCGGCATGTG
GGGAGCCTGATAAACCCATTGTCAAGAAGAGTATAGATGAGCTGTTCAGGATAAGCTTGACCAAATGGTTTTCATTTGGGAGAACATACA
CACACTGGTGGAAGAGAGGGAAGCCAAACTACTGGATGTGATGGAGCTAGCAGAAAAGTTCTGGTGTGATCACATGTCATTGATAGTTAC
CATTAAAGATACTCAAGATTTCATCCGGGACCTGGAAGATCCTGGAATTGATCCTTCAGTAGTAAAACAACAGCAAGAAGCAGCAGAGTT
CCATGACAAGATAGATCAGATCCTTGAGAGCCTGGAACGCATCGTGGAACGTCTGAGGCAGCCACCCTCTATCTCTGCAGAGGTTGAGAA
GATCAAGGAACAGATCAGTGAAAATAAGAATGTGTCAGTAGACATGGAAAAGCTACAGCCGTTGTATGAAACTCTTAAACAGAGGGGAGA
GGAAATGATTGCTAGATCTGGGGGGACTGATAAAGACATATCTGCCAAAGCAACTGCGTGAGTTGATAGCTGAACACAAGCCTCATATAG
ATAAGATGAACAAAACTGGGCCACAGTTACTGGAATTGAGCCCTGGGGAAGGCTTTTCTATCCAAGAGAAGTATGTGGCAGCCGACACCC
TTTACAGTCAAATTAAAGAAGATGTCAAAAAGCGTGCTGTGGCACTGGATGAAGCCATTTCTCAATCAACTCAGAAAAAACTGGACAAGG
TACTGAAGAACTATGATACCATCTGCCAGATTAATTCAGAAAGGTATCTGCAGCTGGAACGGGCACAGTCCCTGGTTAACCAATTCTGGG
AAACATATGAAGAACTTTGGCCATGGCTGACAGAAACACAATCAATCATCTCTCAGCTTCCCGCCCCAGCCCTTGAATATGAAACTCTAA
GGCAGCAGCAGGAAGAACATCGGACATTCACCATGGAGATTTTGAGACACAAGGATATTATTGATGACCTTGTTAAATCTGGGCATAAAA
TCATGACCGCATGCAGTGAAGAGGAAAAGCAATCAATGAAGGTGACATCAGGCTTGAGCAAGACCAGACTTCTGCTCAGCTTCAAGTTCA

>34015_34015_2_GORAB-DST_GORAB_chr1_170521415_ENST00000367763_DST_chr6_56382351_ENST00000421834_length(amino acids)=586AA_BP=
MGYHMWKICGKFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLL
ISVQSRWEKVVQRLVERGRSLDDARKRAKQTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLFQIDEHKEVCAAFEA
KEETYKSLMQKGQQMLARCPKSAETNIDQDINNLKEKWESVETKLNERKAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNV
HMVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQHKLEGALLALGQFQHALDELLA
WLTHTEGLLSEQKPVGGDPKAIEIELAKHHQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDPLMELKLIWDSLEERIINRQAV
FDWVDIAGGKLASMSPIGTDLETVKQQIEELKLNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQTIREEIDGLQEELDIVINLGSELI

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Fusion Gene PPI Analysis for GORAB-DST


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GORAB-DST


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GORAB-DST


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource