FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:GPATCH8-MYO1D (FusionGDB2 ID:34122)

Fusion Gene Summary for GPATCH8-MYO1D

check button Fusion gene summary
Fusion gene informationFusion gene name: GPATCH8-MYO1D
Fusion gene ID: 34122
HgeneTgene
Gene symbol

GPATCH8

MYO1D

Gene ID

23131

4642

Gene nameG-patch domain containing 8myosin ID
SynonymsGPATC8|KIAA0553PPP1R108|myr4
Cytomap

17q21.31

17q11.2

Type of geneprotein-codingprotein-coding
DescriptionG patch domain-containing protein 8unconventional myosin-Idmyosin-I gammaprotein phosphatase 1, regulatory subunit 108
Modification date2020032020200313
UniProtAcc

Q9UKJ3

O94832

Ensembl transtripts involved in fusion geneENST00000588554, ENST00000591680, 
ENST00000592154, ENST00000434000, 
ENST00000586265, 		ENST00000579584, 
ENST00000583621, ENST00000584232, 
ENST00000318217, ENST00000394649, 
Fusion gene scores* DoF score22 X 14 X 12=369628 X 20 X 9=5040
# samples 2729
** MAII scorelog2(27/3696*10)=-3.77493344436523
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(29/5040*10)=-4.11929892837234
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GPATCH8 [Title/Abstract] AND MYO1D [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGPATCH8(42580694)-MYO1D(30821933), # samples:3
Anticipated loss of major functional domain due to fusion event.GPATCH8-MYO1D seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
GPATCH8-MYO1D seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMYO1D

GO:0010923

negative regulation of phosphatase activity

19389623


check buttonFusion gene breakpoints across GPATCH8 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MYO1D (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-1424-01AGPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
ChimerDB4OVTCGA-24-1424GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-


Top

Fusion Gene ORF analysis for GPATCH8-MYO1D

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000588554ENST00000579584GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5CDS-intronENST00000588554ENST00000579584GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
5CDS-intronENST00000588554ENST00000583621GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5CDS-intronENST00000588554ENST00000583621GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
5CDS-intronENST00000588554ENST00000584232GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5CDS-intronENST00000588554ENST00000584232GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
5CDS-intronENST00000591680ENST00000579584GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5CDS-intronENST00000591680ENST00000579584GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
5CDS-intronENST00000591680ENST00000583621GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5CDS-intronENST00000591680ENST00000583621GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
5CDS-intronENST00000591680ENST00000584232GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5CDS-intronENST00000591680ENST00000584232GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
5CDS-intronENST00000592154ENST00000579584GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5CDS-intronENST00000592154ENST00000579584GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
5CDS-intronENST00000592154ENST00000583621GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5CDS-intronENST00000592154ENST00000583621GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
5CDS-intronENST00000592154ENST00000584232GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5CDS-intronENST00000592154ENST00000584232GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
5UTR-3CDSENST00000434000ENST00000318217GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5UTR-3CDSENST00000434000ENST00000318217GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
5UTR-3CDSENST00000434000ENST00000394649GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5UTR-3CDSENST00000434000ENST00000394649GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
5UTR-intronENST00000434000ENST00000579584GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5UTR-intronENST00000434000ENST00000579584GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
5UTR-intronENST00000434000ENST00000583621GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5UTR-intronENST00000434000ENST00000583621GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
5UTR-intronENST00000434000ENST00000584232GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
5UTR-intronENST00000434000ENST00000584232GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
Frame-shiftENST00000588554ENST00000394649GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
Frame-shiftENST00000588554ENST00000394649GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
Frame-shiftENST00000591680ENST00000394649GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
Frame-shiftENST00000591680ENST00000394649GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
Frame-shiftENST00000592154ENST00000394649GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
Frame-shiftENST00000592154ENST00000394649GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
In-frameENST00000588554ENST00000318217GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
In-frameENST00000588554ENST00000318217GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
In-frameENST00000591680ENST00000318217GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
In-frameENST00000591680ENST00000318217GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
In-frameENST00000592154ENST00000318217GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
In-frameENST00000592154ENST00000318217GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
intron-3CDSENST00000586265ENST00000318217GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
intron-3CDSENST00000586265ENST00000318217GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
intron-3CDSENST00000586265ENST00000394649GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
intron-3CDSENST00000586265ENST00000394649GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
intron-intronENST00000586265ENST00000579584GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
intron-intronENST00000586265ENST00000579584GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
intron-intronENST00000586265ENST00000583621GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
intron-intronENST00000586265ENST00000583621GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-
intron-intronENST00000586265ENST00000584232GPATCH8chr17

42580694

-MYO1Dchr17

30821933

-
intron-intronENST00000586265ENST00000584232GPATCH8chr17

42580693

-MYO1Dchr17

30821933

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000591680GPATCH8chr1742580694-ENST00000318217MYO1Dchr1730821933-247076934554126
ENST00000592154GPATCH8chr1742580694-ENST00000318217MYO1Dchr1730821933-2499105963583126
ENST00000588554GPATCH8chr1742580694-ENST00000318217MYO1Dchr1730821933-247581939559126
ENST00000591680GPATCH8chr1742580693-ENST00000318217MYO1Dchr1730821933-247076934554126
ENST00000592154GPATCH8chr1742580693-ENST00000318217MYO1Dchr1730821933-2499105963583126
ENST00000588554GPATCH8chr1742580693-ENST00000318217MYO1Dchr1730821933-247581939559126

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000591680ENST00000318217GPATCH8chr1742580694-MYO1Dchr1730821933-0.93992450.060075462
ENST00000592154ENST00000318217GPATCH8chr1742580694-MYO1Dchr1730821933-0.979683340.020316735
ENST00000588554ENST00000318217GPATCH8chr1742580694-MYO1Dchr1730821933-0.95832490.041675035
ENST00000591680ENST00000318217GPATCH8chr1742580693-MYO1Dchr1730821933-0.93992450.060075462
ENST00000592154ENST00000318217GPATCH8chr1742580693-MYO1Dchr1730821933-0.979683340.020316735
ENST00000588554ENST00000318217GPATCH8chr1742580693-MYO1Dchr1730821933-0.95832490.041675035

Top

Fusion Genomic Features for GPATCH8-MYO1D


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for GPATCH8-MYO1D


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:42580694/chr17:30821933)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GPATCH8

Q9UKJ3

MYO1D

O94832

FUNCTION: Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity). Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity). Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells (By similarity). {ECO:0000250|UniProtKB:F1PRN2, ECO:0000250|UniProtKB:Q63357}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000434000-1989_12401425.0Coiled coilOntology_term=ECO:0000255
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000591680-1889_124151503.0Coiled coilOntology_term=ECO:0000255
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000434000-1989_12401425.0Coiled coilOntology_term=ECO:0000255
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000591680-1889_124151503.0Coiled coilOntology_term=ECO:0000255
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000434000-191384_139001425.0Compositional biasNote=Poly-Ala
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000434000-191472_147801425.0Compositional biasNote=Poly-Ala
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000434000-19665_72001425.0Compositional biasNote=Lys-rich
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000434000-19745_74901425.0Compositional biasNote=Poly-Arg
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000434000-19772_77501425.0Compositional biasNote=Poly-Gly
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000434000-19804_100901425.0Compositional biasNote=Ser-rich
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000591680-181384_1390151503.0Compositional biasNote=Poly-Ala
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000591680-181472_1478151503.0Compositional biasNote=Poly-Ala
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000591680-18665_720151503.0Compositional biasNote=Lys-rich
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000591680-18745_749151503.0Compositional biasNote=Poly-Arg
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000591680-18772_775151503.0Compositional biasNote=Poly-Gly
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000591680-18804_1009151503.0Compositional biasNote=Ser-rich
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000434000-191384_139001425.0Compositional biasNote=Poly-Ala
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000434000-191472_147801425.0Compositional biasNote=Poly-Ala
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000434000-19665_72001425.0Compositional biasNote=Lys-rich
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000434000-19745_74901425.0Compositional biasNote=Poly-Arg
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000434000-19772_77501425.0Compositional biasNote=Poly-Gly
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000434000-19804_100901425.0Compositional biasNote=Ser-rich
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000591680-181384_1390151503.0Compositional biasNote=Poly-Ala
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000591680-181472_1478151503.0Compositional biasNote=Poly-Ala
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000591680-18665_720151503.0Compositional biasNote=Lys-rich
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000591680-18745_749151503.0Compositional biasNote=Poly-Arg
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000591680-18772_775151503.0Compositional biasNote=Poly-Gly
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000591680-18804_1009151503.0Compositional biasNote=Ser-rich
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000434000-1940_8601425.0DomainG-patch
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000591680-1840_86151503.0DomainG-patch
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000434000-1940_8601425.0DomainG-patch
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000591680-1840_86151503.0DomainG-patch
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000434000-19136_16001425.0Zinc fingerC2H2-type
HgeneGPATCH8chr17:42580693chr17:30821933ENST00000591680-18136_160151503.0Zinc fingerC2H2-type
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000434000-19136_16001425.0Zinc fingerC2H2-type
HgeneGPATCH8chr17:42580694chr17:30821933ENST00000591680-18136_160151503.0Zinc fingerC2H2-type
TgeneMYO1Dchr17:42580693chr17:30821933ENST000003182172022699_7199541007.0DomainIQ 1
TgeneMYO1Dchr17:42580693chr17:30821933ENST000003182172022721_7419541007.0DomainIQ 2
TgeneMYO1Dchr17:42580693chr17:30821933ENST000003182172022812_10059541007.0DomainTH1
TgeneMYO1Dchr17:42580693chr17:30821933ENST0000031821720229_6959541007.0DomainMyosin motor
TgeneMYO1Dchr17:42580694chr17:30821933ENST000003182172022699_7199541007.0DomainIQ 1
TgeneMYO1Dchr17:42580694chr17:30821933ENST000003182172022721_7419541007.0DomainIQ 2
TgeneMYO1Dchr17:42580694chr17:30821933ENST000003182172022812_10059541007.0DomainTH1
TgeneMYO1Dchr17:42580694chr17:30821933ENST0000031821720229_6959541007.0DomainMyosin motor
TgeneMYO1Dchr17:42580693chr17:30821933ENST000003182172022102_1099541007.0Nucleotide bindingATP
TgeneMYO1Dchr17:42580694chr17:30821933ENST000003182172022102_1099541007.0Nucleotide bindingATP
TgeneMYO1Dchr17:42580693chr17:30821933ENST000003182172022572_5949541007.0RegionActin-binding
TgeneMYO1Dchr17:42580694chr17:30821933ENST000003182172022572_5949541007.0RegionActin-binding


Top

Fusion Gene Sequence for GPATCH8-MYO1D


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>34122_34122_1_GPATCH8-MYO1D_GPATCH8_chr17_42580693_ENST00000588554_MYO1D_chr17_30821933_ENST00000318217_length(transcript)=2475nt_BP=81nt
GGAGAGCGTCGTCCTGAGAGGAGTGAAGGCGGCAAAATGGCGGACCGCTTCTCCCGCTTCAACGAAGACCGAGACTTTCAGTGAGAAGCG
CCACCTTCAAGTGAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGACGCGGCTCAACCAGCC
CCAGCCCGACTTCACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTGGCCCGGAGCCCGGCC
ACACTCCGAGTCCTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCCCTCCCAGAGGAGCCC
CGCCCCTGTAAGATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCTGTTCAATAAGCCAAA
GACCCTGGTGCCCCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCTTTAGTTGGTGCGGAT
GCCCCGTGGCCAGGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTGGGGATGCAGGACCCC
ACTCTGCGGGAGCCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCTGCTCAGAGTTCGGCG
GACCCACCCCAACCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCTCAGCCAGGAGCCAGT
GGCAGGAGCGGAACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCCACCAAGGCCCCCACC
AGGGCCTCTGACCACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGTGGCTGTGGTCCTCTT
ATAGATACTTTCACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATGAGAACGGGGAGCTGC
CAGGGTGAGGGCAGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAACAGCAAGGGCGGGGT
CAAGACACGGGATGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCAGGATGCCCACCCCGC
CCTCTACACGGCCCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCCCAGCAAAAGCACGTA
TGCTTCAGGGGCCTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGCTGGGAGCAAATGCCC
CATGCGGTGAGAGGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCTCAGGTGGAGTGGGCA
GAGGTGCAAGAGAGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGACCCGGCAGAACCCACC
AAGTGCCTGTGTGCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGCCCACTCCCCATCCCT
GCTTCCCAAAAATTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCTCATTCTCCAAGCCTG
GTCAGCTGCCTGCACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGACACTAGTGGAACCAT
CTAACTGGAACTTCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTATGTTTTAAACACACCA
AAACAGATCATGCCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCTCCCAGCCTTTGGATG
GTGCCTTGGGCCCCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTACTAAAAGCCACAGTA
TGTGGCAACTGCAAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAAGCGGGCATGATTGTA
GACAATGAGGGGGTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAAATTAACTTTATTTCT
AAAGCATATTTTGATTTGCCATCAAGAGCAATAAAGCATTAAATCTTATTTTTAAAGGTGTTCTGCTTATCTGTCACTGAAAACTTGGTG

>34122_34122_1_GPATCH8-MYO1D_GPATCH8_chr17_42580693_ENST00000588554_MYO1D_chr17_30821933_ENST00000318217_length(amino acids)=126AA_BP=
MPHCPLQSGGQRPWWGPWWQRESPRGEPGKDGLTLLDGLFRSCHWLLAEGLALWVTLLTQWLWLAAGSWVGVGPPNSEQSLPELGPQGWL

--------------------------------------------------------------
>34122_34122_2_GPATCH8-MYO1D_GPATCH8_chr17_42580693_ENST00000591680_MYO1D_chr17_30821933_ENST00000318217_length(transcript)=2470nt_BP=76nt
GCGTCGTCCTGAGAGGAGTGAAGGCGGCAAAATGGCGGACCGCTTCTCCCGCTTCAACGAAGACCGAGACTTTCAGTGAGAAGCGCCACC
TTCAAGTGAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGACGCGGCTCAACCAGCCCCAGC
CCGACTTCACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTGGCCCGGAGCCCGGCCACACT
CCGAGTCCTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCCCTCCCAGAGGAGCCCCGCCC
CTGTAAGATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCTGTTCAATAAGCCAAAGACCC
TGGTGCCCCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCTTTAGTTGGTGCGGATGCCCC
GTGGCCAGGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTGGGGATGCAGGACCCCACTCT
GCGGGAGCCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCTGCTCAGAGTTCGGCGGACCC
ACCCCAACCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCTCAGCCAGGAGCCAGTGGCAG
GAGCGGAACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCCACCAAGGCCCCCACCAGGGC
CTCTGACCACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGTGGCTGTGGTCCTCTTATAGA
TACTTTCACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATGAGAACGGGGAGCTGCCAGGG
TGAGGGCAGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAACAGCAAGGGCGGGGTCAAGA
CACGGGATGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCAGGATGCCCACCCCGCCCTCT
ACACGGCCCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCCCAGCAAAAGCACGTATGCTT
CAGGGGCCTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGCTGGGAGCAAATGCCCCATGC
GGTGAGAGGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCTCAGGTGGAGTGGGCAGAGGT
GCAAGAGAGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGACCCGGCAGAACCCACCAAGTG
CCTGTGTGCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGCCCACTCCCCATCCCTGCTTC
CCAAAAATTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCTCATTCTCCAAGCCTGGTCAG
CTGCCTGCACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGACACTAGTGGAACCATCTAAC
TGGAACTTCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTATGTTTTAAACACACCAAAACA
GATCATGCCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCTCCCAGCCTTTGGATGGTGCC
TTGGGCCCCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTACTAAAAGCCACAGTATGTGG
CAACTGCAAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAAGCGGGCATGATTGTAGACAA
TGAGGGGGTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAAATTAACTTTATTTCTAAAGC
ATATTTTGATTTGCCATCAAGAGCAATAAAGCATTAAATCTTATTTTTAAAGGTGTTCTGCTTATCTGTCACTGAAAACTTGGTGAAATT

>34122_34122_2_GPATCH8-MYO1D_GPATCH8_chr17_42580693_ENST00000591680_MYO1D_chr17_30821933_ENST00000318217_length(amino acids)=126AA_BP=
MPHCPLQSGGQRPWWGPWWQRESPRGEPGKDGLTLLDGLFRSCHWLLAEGLALWVTLLTQWLWLAAGSWVGVGPPNSEQSLPELGPQGWL

--------------------------------------------------------------
>34122_34122_3_GPATCH8-MYO1D_GPATCH8_chr17_42580693_ENST00000592154_MYO1D_chr17_30821933_ENST00000318217_length(transcript)=2499nt_BP=105nt
GTCGCAGGAGGGAAGGAGCGAACCGGAGAGCGTCGTCCTGAGAGGAGTGAAGGCGGCAAAATGGCGGACCGCTTCTCCCGCTTCAACGAA
GACCGAGACTTTCAGTGAGAAGCGCCACCTTCAAGTGAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTC
CGTGGAGACGCGGCTCAACCAGCCCCAGCCCGACTTCACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGC
GGAGGCCTGGCCCGGAGCCCGGCCACACTCCGAGTCCTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTG
CGAGGGCCCCTCCCAGAGGAGCCCCGCCCCTGTAAGATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCC
ACGGTCCCTGTTCAATAAGCCAAAGACCCTGGTGCCCCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGG
ATGGTGCCTTTAGTTGGTGCGGATGCCCCGTGGCCAGGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGG
GAAGGGGTGGGGATGCAGGACCCCACTCTGCGGGAGCCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAG
GGAGGCTCTGCTCAGAGTTCGGCGGACCCACCCCAACCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGG
CCAGCCCCTCAGCCAGGAGCCAGTGGCAGGAGCGGAACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACT
CCCTTTGCCACCAAGGCCCCCACCAGGGCCTCTGACCACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTC
GCAGCCTGTGGCTGTGGTCCTCTTATAGATACTTTCACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGA
ACCCTAATGAGAACGGGGAGCTGCCAGGGTGAGGGCAGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTAC
TCAGAGAAACAGCAAGGGCGGGGTCAAGACACGGGATGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAG
GCCAGGCCAGGATGCCCACCCCGCCCTCTACACGGCCCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCA
GTTTCTGCCCAGCAAAAGCACGTATGCTTCAGGGGCCTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGA
AGTAGAGGCTGGGAGCAAATGCCCCATGCGGTGAGAGGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAG
CCAACGCCTCAGGTGGAGTGGGCAGAGGTGCAAGAGAGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCC
CACCCTGACCCGGCAGAACCCACCAAGTGCCTGTGTGCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCG
GTCTCATGCCCACTCCCCATCCCTGCTTCCCAAAAATTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGA
ACCCTTTCTCATTCTCCAAGCCTGGTCAGCTGCCTGCACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATT
ACCAGTAGACACTAGTGGAACCATCTAACTGGAACTTCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATG
CAAATGTATGTTTTAAACACACCAAAACAGATCATGCCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGG
TTCTTTCCTCCCAGCCTTTGGATGGTGCCTTGGGCCCCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTT
TATGATGTACTAAAAGCCACAGTATGTGGCAACTGCAAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGG
GGAAAGGAAGCGGGCATGATTGTAGACAATGAGGGGGTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATT
TTCCAGTAAATTAACTTTATTTCTAAAGCATATTTTGATTTGCCATCAAGAGCAATAAAGCATTAAATCTTATTTTTAAAGGTGTTCTGC

>34122_34122_3_GPATCH8-MYO1D_GPATCH8_chr17_42580693_ENST00000592154_MYO1D_chr17_30821933_ENST00000318217_length(amino acids)=126AA_BP=
MPHCPLQSGGQRPWWGPWWQRESPRGEPGKDGLTLLDGLFRSCHWLLAEGLALWVTLLTQWLWLAAGSWVGVGPPNSEQSLPELGPQGWL

--------------------------------------------------------------
>34122_34122_4_GPATCH8-MYO1D_GPATCH8_chr17_42580694_ENST00000588554_MYO1D_chr17_30821933_ENST00000318217_length(transcript)=2475nt_BP=81nt
GGAGAGCGTCGTCCTGAGAGGAGTGAAGGCGGCAAAATGGCGGACCGCTTCTCCCGCTTCAACGAAGACCGAGACTTTCAGTGAGAAGCG
CCACCTTCAAGTGAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGACGCGGCTCAACCAGCC
CCAGCCCGACTTCACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTGGCCCGGAGCCCGGCC
ACACTCCGAGTCCTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCCCTCCCAGAGGAGCCC
CGCCCCTGTAAGATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCTGTTCAATAAGCCAAA
GACCCTGGTGCCCCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCTTTAGTTGGTGCGGAT
GCCCCGTGGCCAGGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTGGGGATGCAGGACCCC
ACTCTGCGGGAGCCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCTGCTCAGAGTTCGGCG
GACCCACCCCAACCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCTCAGCCAGGAGCCAGT
GGCAGGAGCGGAACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCCACCAAGGCCCCCACC
AGGGCCTCTGACCACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGTGGCTGTGGTCCTCTT
ATAGATACTTTCACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATGAGAACGGGGAGCTGC
CAGGGTGAGGGCAGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAACAGCAAGGGCGGGGT
CAAGACACGGGATGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCAGGATGCCCACCCCGC
CCTCTACACGGCCCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCCCAGCAAAAGCACGTA
TGCTTCAGGGGCCTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGCTGGGAGCAAATGCCC
CATGCGGTGAGAGGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCTCAGGTGGAGTGGGCA
GAGGTGCAAGAGAGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGACCCGGCAGAACCCACC
AAGTGCCTGTGTGCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGCCCACTCCCCATCCCT
GCTTCCCAAAAATTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCTCATTCTCCAAGCCTG
GTCAGCTGCCTGCACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGACACTAGTGGAACCAT
CTAACTGGAACTTCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTATGTTTTAAACACACCA
AAACAGATCATGCCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCTCCCAGCCTTTGGATG
GTGCCTTGGGCCCCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTACTAAAAGCCACAGTA
TGTGGCAACTGCAAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAAGCGGGCATGATTGTA
GACAATGAGGGGGTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAAATTAACTTTATTTCT
AAAGCATATTTTGATTTGCCATCAAGAGCAATAAAGCATTAAATCTTATTTTTAAAGGTGTTCTGCTTATCTGTCACTGAAAACTTGGTG

>34122_34122_4_GPATCH8-MYO1D_GPATCH8_chr17_42580694_ENST00000588554_MYO1D_chr17_30821933_ENST00000318217_length(amino acids)=126AA_BP=
MPHCPLQSGGQRPWWGPWWQRESPRGEPGKDGLTLLDGLFRSCHWLLAEGLALWVTLLTQWLWLAAGSWVGVGPPNSEQSLPELGPQGWL

--------------------------------------------------------------
>34122_34122_5_GPATCH8-MYO1D_GPATCH8_chr17_42580694_ENST00000591680_MYO1D_chr17_30821933_ENST00000318217_length(transcript)=2470nt_BP=76nt
GCGTCGTCCTGAGAGGAGTGAAGGCGGCAAAATGGCGGACCGCTTCTCCCGCTTCAACGAAGACCGAGACTTTCAGTGAGAAGCGCCACC
TTCAAGTGAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGACGCGGCTCAACCAGCCCCAGC
CCGACTTCACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTGGCCCGGAGCCCGGCCACACT
CCGAGTCCTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCCCTCCCAGAGGAGCCCCGCCC
CTGTAAGATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCTGTTCAATAAGCCAAAGACCC
TGGTGCCCCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCTTTAGTTGGTGCGGATGCCCC
GTGGCCAGGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTGGGGATGCAGGACCCCACTCT
GCGGGAGCCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCTGCTCAGAGTTCGGCGGACCC
ACCCCAACCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCTCAGCCAGGAGCCAGTGGCAG
GAGCGGAACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCCACCAAGGCCCCCACCAGGGC
CTCTGACCACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGTGGCTGTGGTCCTCTTATAGA
TACTTTCACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATGAGAACGGGGAGCTGCCAGGG
TGAGGGCAGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAACAGCAAGGGCGGGGTCAAGA
CACGGGATGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCAGGATGCCCACCCCGCCCTCT
ACACGGCCCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCCCAGCAAAAGCACGTATGCTT
CAGGGGCCTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGCTGGGAGCAAATGCCCCATGC
GGTGAGAGGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCTCAGGTGGAGTGGGCAGAGGT
GCAAGAGAGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGACCCGGCAGAACCCACCAAGTG
CCTGTGTGCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGCCCACTCCCCATCCCTGCTTC
CCAAAAATTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCTCATTCTCCAAGCCTGGTCAG
CTGCCTGCACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGACACTAGTGGAACCATCTAAC
TGGAACTTCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTATGTTTTAAACACACCAAAACA
GATCATGCCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCTCCCAGCCTTTGGATGGTGCC
TTGGGCCCCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTACTAAAAGCCACAGTATGTGG
CAACTGCAAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAAGCGGGCATGATTGTAGACAA
TGAGGGGGTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAAATTAACTTTATTTCTAAAGC
ATATTTTGATTTGCCATCAAGAGCAATAAAGCATTAAATCTTATTTTTAAAGGTGTTCTGCTTATCTGTCACTGAAAACTTGGTGAAATT

>34122_34122_5_GPATCH8-MYO1D_GPATCH8_chr17_42580694_ENST00000591680_MYO1D_chr17_30821933_ENST00000318217_length(amino acids)=126AA_BP=
MPHCPLQSGGQRPWWGPWWQRESPRGEPGKDGLTLLDGLFRSCHWLLAEGLALWVTLLTQWLWLAAGSWVGVGPPNSEQSLPELGPQGWL

--------------------------------------------------------------
>34122_34122_6_GPATCH8-MYO1D_GPATCH8_chr17_42580694_ENST00000592154_MYO1D_chr17_30821933_ENST00000318217_length(transcript)=2499nt_BP=105nt
GTCGCAGGAGGGAAGGAGCGAACCGGAGAGCGTCGTCCTGAGAGGAGTGAAGGCGGCAAAATGGCGGACCGCTTCTCCCGCTTCAACGAA
GACCGAGACTTTCAGTGAGAAGCGCCACCTTCAAGTGAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTC
CGTGGAGACGCGGCTCAACCAGCCCCAGCCCGACTTCACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGC
GGAGGCCTGGCCCGGAGCCCGGCCACACTCCGAGTCCTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTG
CGAGGGCCCCTCCCAGAGGAGCCCCGCCCCTGTAAGATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCC
ACGGTCCCTGTTCAATAAGCCAAAGACCCTGGTGCCCCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGG
ATGGTGCCTTTAGTTGGTGCGGATGCCCCGTGGCCAGGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGG
GAAGGGGTGGGGATGCAGGACCCCACTCTGCGGGAGCCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAG
GGAGGCTCTGCTCAGAGTTCGGCGGACCCACCCCAACCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGG
CCAGCCCCTCAGCCAGGAGCCAGTGGCAGGAGCGGAACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACT
CCCTTTGCCACCAAGGCCCCCACCAGGGCCTCTGACCACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTC
GCAGCCTGTGGCTGTGGTCCTCTTATAGATACTTTCACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGA
ACCCTAATGAGAACGGGGAGCTGCCAGGGTGAGGGCAGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTAC
TCAGAGAAACAGCAAGGGCGGGGTCAAGACACGGGATGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAG
GCCAGGCCAGGATGCCCACCCCGCCCTCTACACGGCCCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCA
GTTTCTGCCCAGCAAAAGCACGTATGCTTCAGGGGCCTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGA
AGTAGAGGCTGGGAGCAAATGCCCCATGCGGTGAGAGGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAG
CCAACGCCTCAGGTGGAGTGGGCAGAGGTGCAAGAGAGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCC
CACCCTGACCCGGCAGAACCCACCAAGTGCCTGTGTGCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCG
GTCTCATGCCCACTCCCCATCCCTGCTTCCCAAAAATTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGA
ACCCTTTCTCATTCTCCAAGCCTGGTCAGCTGCCTGCACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATT
ACCAGTAGACACTAGTGGAACCATCTAACTGGAACTTCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATG
CAAATGTATGTTTTAAACACACCAAAACAGATCATGCCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGG
TTCTTTCCTCCCAGCCTTTGGATGGTGCCTTGGGCCCCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTT
TATGATGTACTAAAAGCCACAGTATGTGGCAACTGCAAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGG
GGAAAGGAAGCGGGCATGATTGTAGACAATGAGGGGGTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATT
TTCCAGTAAATTAACTTTATTTCTAAAGCATATTTTGATTTGCCATCAAGAGCAATAAAGCATTAAATCTTATTTTTAAAGGTGTTCTGC

>34122_34122_6_GPATCH8-MYO1D_GPATCH8_chr17_42580694_ENST00000592154_MYO1D_chr17_30821933_ENST00000318217_length(amino acids)=126AA_BP=
MPHCPLQSGGQRPWWGPWWQRESPRGEPGKDGLTLLDGLFRSCHWLLAEGLALWVTLLTQWLWLAAGSWVGVGPPNSEQSLPELGPQGWL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for GPATCH8-MYO1D


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for GPATCH8-MYO1D


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for GPATCH8-MYO1D


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource