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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GPI-UBAP1L (FusionGDB2 ID:34305)

Fusion Gene Summary for GPI-UBAP1L

check button Fusion gene summary
Fusion gene informationFusion gene name: GPI-UBAP1L
Fusion gene ID: 34305
HgeneTgene
Gene symbol

GPI

UBAP1L

Gene ID

10007

390595

Gene nameglucosamine-6-phosphate deaminase 1ubiquitin associated protein 1 like
SynonymsGNP1|GNPDA|GNPI|GPI|HLNUBAP-1L
Cytomap

5q31.3

15q22.31

Type of geneprotein-codingprotein-coding
Descriptionglucosamine-6-phosphate isomerase 1GNPDA 1glcN6P deaminase 1oscillinubiquitin-associated protein 1-like
Modification date2020031320200313
UniProtAcc

PIGT

.
Ensembl transtripts involved in fusion geneENST00000356487, ENST00000415930, 
ENST00000586425, 		ENST00000502113, 
ENST00000559089, 
Fusion gene scores* DoF score27 X 23 X 11=68315 X 5 X 3=75
# samples 285
** MAII scorelog2(28/6831*10)=-4.60859805991281
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GPI [Title/Abstract] AND UBAP1L [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGPI(34859607)-UBAP1L(65386914), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across GPI (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across UBAP1L (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-D3-A2JG-06AGPIchr19

34859607

+UBAP1Lchr15

65386914

-


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Fusion Gene ORF analysis for GPI-UBAP1L

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000356487ENST00000502113GPIchr19

34859607

+UBAP1Lchr15

65386914

-
In-frameENST00000356487ENST00000559089GPIchr19

34859607

+UBAP1Lchr15

65386914

-
In-frameENST00000415930ENST00000502113GPIchr19

34859607

+UBAP1Lchr15

65386914

-
In-frameENST00000415930ENST00000559089GPIchr19

34859607

+UBAP1Lchr15

65386914

-
In-frameENST00000586425ENST00000502113GPIchr19

34859607

+UBAP1Lchr15

65386914

-
In-frameENST00000586425ENST00000559089GPIchr19

34859607

+UBAP1Lchr15

65386914

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000415930GPIchr1934859607+ENST00000559089UBAP1Lchr1565386914-1023689170925251
ENST00000415930GPIchr1934859607+ENST00000502113UBAP1Lchr1565386914-1017689170925251
ENST00000356487GPIchr1934859607+ENST00000559089UBAP1Lchr1565386914-977643172879235
ENST00000356487GPIchr1934859607+ENST00000502113UBAP1Lchr1565386914-971643172879235
ENST00000586425GPIchr1934859607+ENST00000559089UBAP1Lchr1565386914-76142725663212
ENST00000586425GPIchr1934859607+ENST00000502113UBAP1Lchr1565386914-75542725663212

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000415930ENST00000559089GPIchr1934859607+UBAP1Lchr1565386914-0.0024446470.99755543
ENST00000415930ENST00000502113GPIchr1934859607+UBAP1Lchr1565386914-0.0024759960.99752396
ENST00000356487ENST00000559089GPIchr1934859607+UBAP1Lchr1565386914-0.0019115980.9980884
ENST00000356487ENST00000502113GPIchr1934859607+UBAP1Lchr1565386914-0.0019331080.99806696
ENST00000586425ENST00000559089GPIchr1934859607+UBAP1Lchr1565386914-0.0015729730.99842703
ENST00000586425ENST00000502113GPIchr1934859607+UBAP1Lchr1565386914-0.0016162270.99838376

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Fusion Genomic Features for GPI-UBAP1L


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GPI-UBAP1L


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:34859607/chr15:65386914)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GPI

PIGT

.
578FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGPIchr19:34859607chr15:65386914ENST00000415930+518159_160173570.0RegionGlucose-6-phosphate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGPIchr19:34859607chr15:65386914ENST00000356487+418159_160134559.0RegionGlucose-6-phosphate binding
HgeneGPIchr19:34859607chr15:65386914ENST00000356487+418210_215134559.0RegionGlucose-6-phosphate binding
HgeneGPIchr19:34859607chr15:65386914ENST00000415930+518210_215173570.0RegionGlucose-6-phosphate binding
TgeneUBAP1Lchr19:34859607chr15:65386914ENST0000050211325188_258303382.0Compositional biasNote=Pro-rich
TgeneUBAP1Lchr19:34859607chr15:65386914ENST0000055908936188_258303382.0Compositional biasNote=Pro-rich
TgeneUBAP1Lchr19:34859607chr15:65386914ENST00000502113254_50303382.0DomainUMA
TgeneUBAP1Lchr19:34859607chr15:65386914ENST00000559089364_50303382.0DomainUMA


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Fusion Gene Sequence for GPI-UBAP1L


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>34305_34305_1_GPI-UBAP1L_GPI_chr19_34859607_ENST00000356487_UBAP1L_chr15_65386914_ENST00000502113_length(transcript)=971nt_BP=643nt
AGAGAGGAGCTGAGGCCCCAGATCAGCGGCCGCGGGCAAGGTCGCTCAGCGGGCACCCGGCCTGGGTATCGGGGCGCGGGTCGGGGGCGG
GGCCGGGGCTCAGGGGTGGGGCCGGGCCGGGCCGGGCCGGGCGCCTGCGCCATAAAGGCCGCCGCGCGCCCACGCGCCTCGCTTGCTGCG
CGCTGCCGGCGCTCCTTCCTCCTCGGCTCGCGTCTCACTCAGTGTACCTTCTAGTCCCGCCATGGCCGCTCTCACCCGGGACCCCCAGTT
CCAGAAGCTGCAGCAATGGTACCGCGAGCACCGCTCCGAGCTGAACCTGCGCCGCCTCTTCGATGCCAACAAGGACCGCTTCAACCACTT
CAGCTTGACCCTCAACACCAACCATGGGCATATCCTGGTGGATTACTCCAAGAACCTGGTGACGGAGGACGTGATGCGGATGCTGGTGGA
CTTGGCCAAGTCCAGGGGCGTGGAGGCCGCCCGGGAGCGGATGTTCAATGGTGAGAAGATCAACTACACCGAGGGTCGAGCCGTGCTGCA
CGTGGCTCTGCGGAACCGGTCAAACACACCCATCCTGGTAGACGGCAAGGATGTGATGCCAGAGGTCAACAAGGTTCTGGACAAGATGAA
GTCTTTCTGCCAGTTTCTCAGCTACCTCAGTGCCTGTGACCGCCTGTTACGTCAGGGATATGAGGAAGGCCTGGTGGATGAGGCCATGGA
GATGTTCCAGTTCTCCGAGAGCCAGGCAGGGGAGTTCCTGCGCCTCTGGGAGCAGTTCAGTGACATGGGCTTCCAGCAGGACCGGATCAA
GGAGGTGCTGCTGGTCCATGGCAACCGCCGAGAGCAAGCCCTGGAGGAGCTGGTGGCCTGTGCCCAGTGACCACGGAGGCACTCCACGAT

>34305_34305_1_GPI-UBAP1L_GPI_chr19_34859607_ENST00000356487_UBAP1L_chr15_65386914_ENST00000502113_length(amino acids)=235AA_BP=156
MLRAAGAPSSSARVSLSVPSSPAMAALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRM
LVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQFLSYLSACDRLLRQGYEEGLVDE

--------------------------------------------------------------
>34305_34305_2_GPI-UBAP1L_GPI_chr19_34859607_ENST00000356487_UBAP1L_chr15_65386914_ENST00000559089_length(transcript)=977nt_BP=643nt
AGAGAGGAGCTGAGGCCCCAGATCAGCGGCCGCGGGCAAGGTCGCTCAGCGGGCACCCGGCCTGGGTATCGGGGCGCGGGTCGGGGGCGG
GGCCGGGGCTCAGGGGTGGGGCCGGGCCGGGCCGGGCCGGGCGCCTGCGCCATAAAGGCCGCCGCGCGCCCACGCGCCTCGCTTGCTGCG
CGCTGCCGGCGCTCCTTCCTCCTCGGCTCGCGTCTCACTCAGTGTACCTTCTAGTCCCGCCATGGCCGCTCTCACCCGGGACCCCCAGTT
CCAGAAGCTGCAGCAATGGTACCGCGAGCACCGCTCCGAGCTGAACCTGCGCCGCCTCTTCGATGCCAACAAGGACCGCTTCAACCACTT
CAGCTTGACCCTCAACACCAACCATGGGCATATCCTGGTGGATTACTCCAAGAACCTGGTGACGGAGGACGTGATGCGGATGCTGGTGGA
CTTGGCCAAGTCCAGGGGCGTGGAGGCCGCCCGGGAGCGGATGTTCAATGGTGAGAAGATCAACTACACCGAGGGTCGAGCCGTGCTGCA
CGTGGCTCTGCGGAACCGGTCAAACACACCCATCCTGGTAGACGGCAAGGATGTGATGCCAGAGGTCAACAAGGTTCTGGACAAGATGAA
GTCTTTCTGCCAGTTTCTCAGCTACCTCAGTGCCTGTGACCGCCTGTTACGTCAGGGATATGAGGAAGGCCTGGTGGATGAGGCCATGGA
GATGTTCCAGTTCTCCGAGAGCCAGGCAGGGGAGTTCCTGCGCCTCTGGGAGCAGTTCAGTGACATGGGCTTCCAGCAGGACCGGATCAA
GGAGGTGCTGCTGGTCCATGGCAACCGCCGAGAGCAAGCCCTGGAGGAGCTGGTGGCCTGTGCCCAGTGACCACGGAGGCACTCCACGAT

>34305_34305_2_GPI-UBAP1L_GPI_chr19_34859607_ENST00000356487_UBAP1L_chr15_65386914_ENST00000559089_length(amino acids)=235AA_BP=156
MLRAAGAPSSSARVSLSVPSSPAMAALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRM
LVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQFLSYLSACDRLLRQGYEEGLVDE

--------------------------------------------------------------
>34305_34305_3_GPI-UBAP1L_GPI_chr19_34859607_ENST00000415930_UBAP1L_chr15_65386914_ENST00000502113_length(transcript)=1017nt_BP=689nt
AATAGCCCTTACCACCAGCAGACACACATCATCTGTTGTACTTGCTTATTTGGCACATATGTATCCACAGCGCCTAGAACACTGCCTGTA
ACGTGGAAGGTGTTCGATCTATAGAGTTTTGTCGAATGAATGAATGAAGCCGACTAGTGCACAGGGAGTGCAGCGGCGCGATGGTAGCTC
TCTGCAGCCTCCAACACCTGGGCTCCAGTGATCCCCGGGCTCTGCCCACCCTCCCCACTGCCACTTCCGGGCAGAGGCCAGCAAAGCGGC
GGCGCAAGAGTCCCGCCATGGCCGCTCTCACCCGGGACCCCCAGTTCCAGAAGCTGCAGCAATGGTACCGCGAGCACCGCTCCGAGCTGA
ACCTGCGCCGCCTCTTCGATGCCAACAAGGACCGCTTCAACCACTTCAGCTTGACCCTCAACACCAACCATGGGCATATCCTGGTGGATT
ACTCCAAGAACCTGGTGACGGAGGACGTGATGCGGATGCTGGTGGACTTGGCCAAGTCCAGGGGCGTGGAGGCCGCCCGGGAGCGGATGT
TCAATGGTGAGAAGATCAACTACACCGAGGGTCGAGCCGTGCTGCACGTGGCTCTGCGGAACCGGTCAAACACACCCATCCTGGTAGACG
GCAAGGATGTGATGCCAGAGGTCAACAAGGTTCTGGACAAGATGAAGTCTTTCTGCCAGTTTCTCAGCTACCTCAGTGCCTGTGACCGCC
TGTTACGTCAGGGATATGAGGAAGGCCTGGTGGATGAGGCCATGGAGATGTTCCAGTTCTCCGAGAGCCAGGCAGGGGAGTTCCTGCGCC
TCTGGGAGCAGTTCAGTGACATGGGCTTCCAGCAGGACCGGATCAAGGAGGTGCTGCTGGTCCATGGCAACCGCCGAGAGCAAGCCCTGG
AGGAGCTGGTGGCCTGTGCCCAGTGACCACGGAGGCACTCCACGATGCCTGGGCATCTAGGCCCAATGCCAGACCTGGCAACCCATCCTA

>34305_34305_3_GPI-UBAP1L_GPI_chr19_34859607_ENST00000415930_UBAP1L_chr15_65386914_ENST00000502113_length(amino acids)=251AA_BP=172
MVALCSLQHLGSSDPRALPTLPTATSGQRPAKRRRKSPAMAALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHI
LVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQFLSYLSA

--------------------------------------------------------------
>34305_34305_4_GPI-UBAP1L_GPI_chr19_34859607_ENST00000415930_UBAP1L_chr15_65386914_ENST00000559089_length(transcript)=1023nt_BP=689nt
AATAGCCCTTACCACCAGCAGACACACATCATCTGTTGTACTTGCTTATTTGGCACATATGTATCCACAGCGCCTAGAACACTGCCTGTA
ACGTGGAAGGTGTTCGATCTATAGAGTTTTGTCGAATGAATGAATGAAGCCGACTAGTGCACAGGGAGTGCAGCGGCGCGATGGTAGCTC
TCTGCAGCCTCCAACACCTGGGCTCCAGTGATCCCCGGGCTCTGCCCACCCTCCCCACTGCCACTTCCGGGCAGAGGCCAGCAAAGCGGC
GGCGCAAGAGTCCCGCCATGGCCGCTCTCACCCGGGACCCCCAGTTCCAGAAGCTGCAGCAATGGTACCGCGAGCACCGCTCCGAGCTGA
ACCTGCGCCGCCTCTTCGATGCCAACAAGGACCGCTTCAACCACTTCAGCTTGACCCTCAACACCAACCATGGGCATATCCTGGTGGATT
ACTCCAAGAACCTGGTGACGGAGGACGTGATGCGGATGCTGGTGGACTTGGCCAAGTCCAGGGGCGTGGAGGCCGCCCGGGAGCGGATGT
TCAATGGTGAGAAGATCAACTACACCGAGGGTCGAGCCGTGCTGCACGTGGCTCTGCGGAACCGGTCAAACACACCCATCCTGGTAGACG
GCAAGGATGTGATGCCAGAGGTCAACAAGGTTCTGGACAAGATGAAGTCTTTCTGCCAGTTTCTCAGCTACCTCAGTGCCTGTGACCGCC
TGTTACGTCAGGGATATGAGGAAGGCCTGGTGGATGAGGCCATGGAGATGTTCCAGTTCTCCGAGAGCCAGGCAGGGGAGTTCCTGCGCC
TCTGGGAGCAGTTCAGTGACATGGGCTTCCAGCAGGACCGGATCAAGGAGGTGCTGCTGGTCCATGGCAACCGCCGAGAGCAAGCCCTGG
AGGAGCTGGTGGCCTGTGCCCAGTGACCACGGAGGCACTCCACGATGCCTGGGCATCTAGGCCCAATGCCAGACCTGGCAACCCATCCTA

>34305_34305_4_GPI-UBAP1L_GPI_chr19_34859607_ENST00000415930_UBAP1L_chr15_65386914_ENST00000559089_length(amino acids)=251AA_BP=172
MVALCSLQHLGSSDPRALPTLPTATSGQRPAKRRRKSPAMAALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHI
LVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQFLSYLSA

--------------------------------------------------------------
>34305_34305_5_GPI-UBAP1L_GPI_chr19_34859607_ENST00000586425_UBAP1L_chr15_65386914_ENST00000502113_length(transcript)=755nt_BP=427nt
ACTCAGTGTACCTTCTAGTCCCGCCATGGCCGCTCTCACCCGGGACCCCCAGTTCCAGAAGCTGCAGCAATGGTACCGCGAGCACCGCTC
CGAGCTGAACCTGCGCCGCCTCTTCGATGCCAACAAGGACCGCTTCAACCACTTCAGCTTGACCCTCAACACCAACCATGGGCATATCCT
GGTGGATTACTCCAAGAACCTGGTGACGGAGGACGTGATGCGGATGCTGGTGGACTTGGCCAAGTCCAGGGGCGTGGAGGCCGCCCGGGA
GCGGATGTTCAATGGTGAGAAGATCAACTACACCGAGGGTCGAGCCGTGCTGCACGTGGCTCTGCGGAACCGGTCAAACACACCCATCCT
GGTAGACGGCAAGGATGTGATGCCAGAGGTCAACAAGGTTCTGGACAAGATGAAGTCTTTCTGCCAGTTTCTCAGCTACCTCAGTGCCTG
TGACCGCCTGTTACGTCAGGGATATGAGGAAGGCCTGGTGGATGAGGCCATGGAGATGTTCCAGTTCTCCGAGAGCCAGGCAGGGGAGTT
CCTGCGCCTCTGGGAGCAGTTCAGTGACATGGGCTTCCAGCAGGACCGGATCAAGGAGGTGCTGCTGGTCCATGGCAACCGCCGAGAGCA
AGCCCTGGAGGAGCTGGTGGCCTGTGCCCAGTGACCACGGAGGCACTCCACGATGCCTGGGCATCTAGGCCCAATGCCAGACCTGGCAAC

>34305_34305_5_GPI-UBAP1L_GPI_chr19_34859607_ENST00000586425_UBAP1L_chr15_65386914_ENST00000502113_length(amino acids)=212AA_BP=133
MAALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKI
NYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQFLSYLSACDRLLRQGYEEGLVDEAMEMFQFSESQAGEFLRLWEQFS

--------------------------------------------------------------
>34305_34305_6_GPI-UBAP1L_GPI_chr19_34859607_ENST00000586425_UBAP1L_chr15_65386914_ENST00000559089_length(transcript)=761nt_BP=427nt
ACTCAGTGTACCTTCTAGTCCCGCCATGGCCGCTCTCACCCGGGACCCCCAGTTCCAGAAGCTGCAGCAATGGTACCGCGAGCACCGCTC
CGAGCTGAACCTGCGCCGCCTCTTCGATGCCAACAAGGACCGCTTCAACCACTTCAGCTTGACCCTCAACACCAACCATGGGCATATCCT
GGTGGATTACTCCAAGAACCTGGTGACGGAGGACGTGATGCGGATGCTGGTGGACTTGGCCAAGTCCAGGGGCGTGGAGGCCGCCCGGGA
GCGGATGTTCAATGGTGAGAAGATCAACTACACCGAGGGTCGAGCCGTGCTGCACGTGGCTCTGCGGAACCGGTCAAACACACCCATCCT
GGTAGACGGCAAGGATGTGATGCCAGAGGTCAACAAGGTTCTGGACAAGATGAAGTCTTTCTGCCAGTTTCTCAGCTACCTCAGTGCCTG
TGACCGCCTGTTACGTCAGGGATATGAGGAAGGCCTGGTGGATGAGGCCATGGAGATGTTCCAGTTCTCCGAGAGCCAGGCAGGGGAGTT
CCTGCGCCTCTGGGAGCAGTTCAGTGACATGGGCTTCCAGCAGGACCGGATCAAGGAGGTGCTGCTGGTCCATGGCAACCGCCGAGAGCA
AGCCCTGGAGGAGCTGGTGGCCTGTGCCCAGTGACCACGGAGGCACTCCACGATGCCTGGGCATCTAGGCCCAATGCCAGACCTGGCAAC

>34305_34305_6_GPI-UBAP1L_GPI_chr19_34859607_ENST00000586425_UBAP1L_chr15_65386914_ENST00000559089_length(amino acids)=212AA_BP=133
MAALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKI
NYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQFLSYLSACDRLLRQGYEEGLVDEAMEMFQFSESQAGEFLRLWEQFS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for GPI-UBAP1L


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GPI-UBAP1L


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GPI-UBAP1L


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource