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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GPR155-CHN1 (FusionGDB2 ID:34395)

Fusion Gene Summary for GPR155-CHN1

check button Fusion gene summary
Fusion gene informationFusion gene name: GPR155-CHN1
Fusion gene ID: 34395
HgeneTgene
Gene symbol

GPR155

CHN1

Gene ID

151556

1959

Gene nameG protein-coupled receptor 155early growth response 2
SynonymsDEP.7|DEPDC3|PGR22AT591|CHN1|CMT1D|CMT4E|KROX20
Cytomap

2q31.1

10q21.3

Type of geneprotein-codingprotein-coding
Descriptionintegral membrane protein GPR155G-protein coupled receptor PGR22E3 SUMO-protein ligase EGR2E3 SUMO-protein transferase ERG2KROX-20, Drosophila, homolog (early growth response-2)early growth response protein 2zinc finger protein Krox-20
Modification date2020031320200328
UniProtAcc

Q7Z3F1

P15882

Ensembl transtripts involved in fusion geneENST00000295500, ENST00000392551, 
ENST00000392552, ENST00000459996, 
ENST00000295497, ENST00000409156, 
ENST00000409597, ENST00000488080, 
ENST00000409900, 
Fusion gene scores* DoF score5 X 5 X 4=1009 X 8 X 6=432
# samples 58
** MAII scorelog2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/432*10)=-2.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GPR155 [Title/Abstract] AND CHN1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGPR155(175318465)-CHN1(175677210), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCHN1

GO:0045944

positive regulation of transcription by RNA polymerase II

12687019


check buttonFusion gene breakpoints across GPR155 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CHN1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E9-A1NA-01AGPR155chr2

175318465

-CHN1chr2

175677210

-


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Fusion Gene ORF analysis for GPR155-CHN1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000295500ENST00000295497GPR155chr2

175318465

-CHN1chr2

175677210

-
5CDS-5UTRENST00000295500ENST00000409156GPR155chr2

175318465

-CHN1chr2

175677210

-
5CDS-5UTRENST00000295500ENST00000409597GPR155chr2

175318465

-CHN1chr2

175677210

-
5CDS-5UTRENST00000295500ENST00000488080GPR155chr2

175318465

-CHN1chr2

175677210

-
5CDS-5UTRENST00000392551ENST00000295497GPR155chr2

175318465

-CHN1chr2

175677210

-
5CDS-5UTRENST00000392551ENST00000409156GPR155chr2

175318465

-CHN1chr2

175677210

-
5CDS-5UTRENST00000392551ENST00000409597GPR155chr2

175318465

-CHN1chr2

175677210

-
5CDS-5UTRENST00000392551ENST00000488080GPR155chr2

175318465

-CHN1chr2

175677210

-
5CDS-5UTRENST00000392552ENST00000295497GPR155chr2

175318465

-CHN1chr2

175677210

-
5CDS-5UTRENST00000392552ENST00000409156GPR155chr2

175318465

-CHN1chr2

175677210

-
5CDS-5UTRENST00000392552ENST00000409597GPR155chr2

175318465

-CHN1chr2

175677210

-
5CDS-5UTRENST00000392552ENST00000488080GPR155chr2

175318465

-CHN1chr2

175677210

-
Frame-shiftENST00000295500ENST00000409900GPR155chr2

175318465

-CHN1chr2

175677210

-
Frame-shiftENST00000392552ENST00000409900GPR155chr2

175318465

-CHN1chr2

175677210

-
In-frameENST00000392551ENST00000409900GPR155chr2

175318465

-CHN1chr2

175677210

-
intron-3CDSENST00000459996ENST00000409900GPR155chr2

175318465

-CHN1chr2

175677210

-
intron-5UTRENST00000459996ENST00000295497GPR155chr2

175318465

-CHN1chr2

175677210

-
intron-5UTRENST00000459996ENST00000409156GPR155chr2

175318465

-CHN1chr2

175677210

-
intron-5UTRENST00000459996ENST00000409597GPR155chr2

175318465

-CHN1chr2

175677210

-
intron-5UTRENST00000459996ENST00000488080GPR155chr2

175318465

-CHN1chr2

175677210

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000392551GPR155chr2175318465-ENST00000409900CHN1chr2175677210-359621752992842847

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000392551ENST00000409900GPR155chr2175318465-CHN1chr2175677210-0.0003767760.9996232

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Fusion Genomic Features for GPR155-CHN1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GPR155-CHN1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:175318465/chr2:175677210)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GPR155

Q7Z3F1

CHN1

P15882

FUNCTION: GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217483_486625871.0Compositional biasNote=Poly-Ile
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217483_486625871.0Compositional biasNote=Poly-Ile
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116483_486625871.0Compositional biasNote=Poly-Ile
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217105_125625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217134_154625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217168_188625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217214_234625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217244_264625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217274_294625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217316_336625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217347_367625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217382_402625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-121739_59625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217415_435625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217439_459625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217481_501625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217521_541625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-121780_100625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217105_125625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217134_154625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217168_188625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217214_234625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217244_264625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217274_294625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217316_336625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217347_367625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217382_402625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-121739_59625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217415_435625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217439_459625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217481_501625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217521_541625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-121780_100625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116105_125625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116134_154625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116168_188625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116214_234625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116244_264625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116274_294625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116316_336625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116347_367625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116382_402625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-111639_59625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116415_435625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116439_459625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116481_501625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116521_541625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-111680_100625871.0TransmembraneHelical
TgeneCHN1chr2:175318465chr2:175677210ENST0000029549717268_459112335.0DomainRho-GAP
TgeneCHN1chr2:175318465chr2:175677210ENST00000409156713268_459211434.0DomainRho-GAP
TgeneCHN1chr2:175318465chr2:175677210ENST00000409900713268_459237460.0DomainRho-GAP
TgeneCHN1chr2:175318465chr2:175677210ENST0000029549717205_255112335.0Zinc fingerPhorbol-ester/DAG-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217757_835625871.0DomainDEP
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217757_835625871.0DomainDEP
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116757_835625871.0DomainDEP
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217661_681625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000295500-1217692_712625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217661_681625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392551-1217692_712625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116661_681625871.0TransmembraneHelical
HgeneGPR155chr2:175318465chr2:175677210ENST00000392552-1116692_712625871.0TransmembraneHelical
TgeneCHN1chr2:175318465chr2:175677210ENST000002954971749_135112335.0DomainSH2
TgeneCHN1chr2:175318465chr2:175677210ENST0000040915671349_135211434.0DomainSH2
TgeneCHN1chr2:175318465chr2:175677210ENST0000040990071349_135237460.0DomainSH2
TgeneCHN1chr2:175318465chr2:175677210ENST00000409156713205_255211434.0Zinc fingerPhorbol-ester/DAG-type
TgeneCHN1chr2:175318465chr2:175677210ENST00000409900713205_255237460.0Zinc fingerPhorbol-ester/DAG-type


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Fusion Gene Sequence for GPR155-CHN1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>34395_34395_1_GPR155-CHN1_GPR155_chr2_175318465_ENST00000392551_CHN1_chr2_175677210_ENST00000409900_length(transcript)=3596nt_BP=2175nt
GGGGGCGGGGCCTCGCGGCCGGCGAGGGGCTGAGCTGACAGGGCCGCATCGGCTTACCCCACCTTACTTTATCGGAACGTGCCTAAGCTG
CTGCAGCTGGCACCCGGTTGCGCTCGGCGAAGAGGGCTGGGGGCGGGAGATGACGGTGGTCTTCTCCCTGCTTGGCACCCTGCGAGCACC
AGCTCCCTTCTCCTCGCCACTCCAAGGTTGCAGACGAAGCAGATGTGATTATAAAGACTTCAGTGGAATAATCGCAAGTTCCCATGTGAG
ATCTGGTTGGAGTTGGAGGGTGAGAGAAAATGAATTCTAATTTACCTGCAGAGAACTTAACCATTGCAGTCAATATGACCAAGACTTTGC
CTACAGCAGTAACGCATGGATTTAATTCCACTAATGACCCACCTTCAATGTCAATTACAAGGCTTTTTCCAGCCTTACTGGAATGCTTTG
GCATTGTCCTTTGTGGCTACATAGCAGGAAGGGCCAATGTCATAACATCAACCCAGGCCAAAGGACTAGGAAATTTTGTCTCCAGATTTG
CACTTCCAGCTTTATTATTCAAAAACATGGTTGTACTTAATTTTTCCAATGTGGACTGGTCCTTCCTATATAGTATCTTAATTGCCAAAG
CTTCTGTATTTTTCATTGTATGTGTATTAACCTTATTGGTTGCCAGTCCTGATAGTCGATTTAGCAAAGCTGGACTATTCCCTATTTTTG
CTACACAAAGTAATGACTTTGCATTGGGATACCCTATAGTTGAAGCTTTATATCAAACTACATACCCAGAATATCTCCAGTACATTTATT
TGGTGGCACCAATATCTCTTATGATGTTAAACCCTATAGGGTTTATTTTCTGTGAAATCCAAAAGTGGAAAGACACTCAAAATGCTTCTC
AAAATAAAATAAAAATTGTGGGACTCGGACTCCTGCGTGTATTACAGAACCCAATAGTATTTATGGTCTTCATTGGCATCGCCTTCAATT
TTATTCTTGATCGAAAGGTACCTGTATATGTCGAAAATTTTCTTGATGGACTTGGAAATTCTTTTTCTGGATCAGCCCTATTTTATCTTG
GTCTCACGATGGTGGGAAAAATAAAGAGACTGAAGAAGTCGGCATTTGTAGTACTAATTCTTCTCATCACAGCTAAACTTCTGGTGCTGC
CACTTCTGTGCAGAGAAATGGTGGAACTCTTGGACAAGGGCGACAGTGTGGTGAACCATACAAGTTTATCAAATTATGCATTTCTGTATG
GTGTATTTCCTGTAGCACCAGGAGTGGCTATCTTTGCAACACAATTCAACATGGAAGTAGAAATTATAACCTCAGGGATGGTGATAAGCA
CATTTGTGTCTGCTCCCATCATGTACGTTTCTGCCTGGTTACTGACCTTTCCCACTATGGACCCTAAGCCATTGGCATATGCCATCCAGA
ATGTTAGTTTTGATATAAGTATTGTCAGCCTGATCTCCTTGATCTGGTCTCTGGCTATTCTTCTTTTGAGTAAGAAATATAAACAGCTTC
CTCATATGCTTACAACTAATTTACTCATTGCTCAGTCTATTGTCTGTGCTGGAATGATGATATGGAATTTTGTTAAAGAAAAAAATTTTG
TTGGACAAATTTTGGTGTTTGTTCTATTGTACAGCTCCCTCTATAGCACCTACCTGTGGACAGGCCTTCTAGCAATTTCTTTGTTTCTTT
TGAAAAAGCGAGAGAGGGTACAAATTCCTGTTGGAATAATCATAATATCTGGCTGGGGAATTCCTGCTCTCCTTGTTGGTGTTCTTTTGA
TAACTGGAAAACACAATGGAGATAGCATTGACTCAGCCTTCTTTTATGGAAAAGAACAGATGATCACCACAGCAGTCACCCTGTTCTGCA
GCATCCTGATAGCTGGCATATCCCTCATGTGCATGAACCAGACTGCCCAAGCAGGAAGCTATGAAGGTTTCGATCAGTCTCAGAGCCACA
AAGTGGTGGAGCCTGGAAATACTGCTTTTGAGGAGAGTCCAGCACCAGTAAATGAACCAGAACTTTTTACAAGCTCTATTCCAGAAACAA
GTTGCTGCTCCTGCTCCATGGGAAATGGTGAATTACACTGCCCATCAATAGAGCCAATAGCAAACACAAGCACCAGTGAGCCTGTGATTC
CTTCGTTTGAGAAAAATTGTGGTTTGAATGTTCATAAGCAGTGTTCCAAGATGGTCCCAAATGACTGTAAGCCAGACTTGAAGCATGTCA
AAAAGGTGTACAGCTGTGACCTTACGACGCTCGTGAAAGCACATACCACTAAGCGGCCAATGGTGGTAGACATGTGCATCAGGGAGATTG
AGTCTAGAGGTCTTAATTCTGAAGGACTATACCGAGTATCAGGATTTAGTGACCTAATTGAAGATGTCAAGATGGCTTTCGACAGAGATG
GTGAGAAGGCAGATATTTCTGTGAACATGTATGAAGATATCAACATTATCACTGGTGCACTTAAACTGTACTTCAGGGATTTGCCAATTC
CACTCATTACATATGATGCCTACCCTAAGTTTATAGAATCTGCCAAAATTATGGATCCGGATGAGCAATTGGAAACCCTTCATGAAGCAC
TGAAACTACTGCCACCTGCTCACTGCGAAACCCTCCGGTACCTCATGGCACATCTAAAGAGAGTGACCCTCCACGAAAAGGAGAATCTTA
TGAATGCAGAGAACCTTGGAATCGTCTTTGGACCCACCCTTATGAGATCTCCAGAACTAGACGCCATGGCTGCATTGAATGATATACGGT
ATCAGAGACTGGTGGTGGAGCTGCTTATCAAAAACGAAGACATTTTATTTTAAATTTTTAATTTGAGGGGAAAAGAAATGTTTTACAGAT
GAAGGAATGTTTTATAGTAATTTAATTTGCTCCTGTAGCTGCATTATTTCTTGATTAGAGGTTTGGGCATATAACCAGATTAAAGTGAAG
GAACTTTCTGTTGTTTTTGTAGCACCGCTCAGCTGTCTTGTAAAACAGTGAACACACGCTTTCTGGTTCTAGTAATCCTGGGTGTTTATC
ACGTTCAGAGAAACTCAAGCTATTGCATGATTAGCCCCCTATCTGGCAAGGAAACCCCATACAGAAGAAACAACAAACCTGCGCCTGCAC
CGCCTCTGCGTCCTGGGTAGTCTGTGCTTGTAATCCAGCATGTTTCACAGAGTAAGCCTGTTGTGACTTTGCTTTTGGGGTCTATGTCAT
TGGTTTCTGATGCTTGTACAAACACGCACACACAAATGGATAAAACAGCACCTCTGGCTGTTACATTACCATAAACCATATCACATGCCT
ACATTTTACAAATGATTTCTGGTTTCTCTTAGTTCTTCTCTAACATAGTACTTTCTTTCCAGCAAAAGCAAAATGTGTTTTCAGATTTGT
TACTTTAATAAAGGTTATCCATACCAATAAAAAGTGTACAACACAGCATTTTCTGTTAAATTATTATTGGTTTTCAGTTGTAATTTGGTA

>34395_34395_1_GPR155-CHN1_GPR155_chr2_175318465_ENST00000392551_CHN1_chr2_175677210_ENST00000409900_length(amino acids)=847AA_BP=626
MNSNLPAENLTIAVNMTKTLPTAVTHGFNSTNDPPSMSITRLFPALLECFGIVLCGYIAGRANVITSTQAKGLGNFVSRFALPALLFKNM
VVLNFSNVDWSFLYSILIAKASVFFIVCVLTLLVASPDSRFSKAGLFPIFATQSNDFALGYPIVEALYQTTYPEYLQYIYLVAPISLMML
NPIGFIFCEIQKWKDTQNASQNKIKIVGLGLLRVLQNPIVFMVFIGIAFNFILDRKVPVYVENFLDGLGNSFSGSALFYLGLTMVGKIKR
LKKSAFVVLILLITAKLLVLPLLCREMVELLDKGDSVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYV
SAWLLTFPTMDPKPLAYAIQNVSFDISIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLIAQSIVCAGMMIWNFVKEKNFVGQILVFVLL
YSSLYSTYLWTGLLAISLFLLKKRERVQIPVGIIIISGWGIPALLVGVLLITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIAGISLM
CMNQTAQAGSYEGFDQSQSHKVVEPGNTAFEESPAPVNEPELFTSSIPETSCCSCSMGNGELHCPSIEPIANTSTSEPVIPSFEKNCGLN
VHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNM
YEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVF

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Fusion Gene PPI Analysis for GPR155-CHN1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GPR155-CHN1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GPR155-CHN1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource