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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:GRAMD4-TBC1D22A (FusionGDB2 ID:34605)

Fusion Gene Summary for GRAMD4-TBC1D22A

Fusion gene summary

Fusion gene information	Fusion gene name: GRAMD4-TBC1D22A
	Fusion gene ID: 34605
		Hgene	Tgene
	Gene symbol	GRAMD4	TBC1D22A
	Gene ID	23151	25771
	Gene name	GRAM domain containing 4	TBC1 domain family member 22A
	Synonyms	DIP	C22orf4\|HSC79E021
	Cytomap	22q13.31	22q13.31
	Type of gene	protein-coding	protein-coding
	Description	GRAM domain-containing protein 4death-inducing-protein	TBC1 domain family member 22Aputative GTPase activator
	Modification date	20200313	20200313
	UniProtAcc	Q6IC98	.
	Ensembl transtripts involved in fusion gene	ENST00000361034, ENST00000406902, ENST00000490378, ENST00000408031,	ENST00000355704, ENST00000380995, ENST00000406733, ENST00000407381, ENST00000472791, ENST00000337137,
Fusion gene scores	* DoF score	16 X 11 X 7=1232	22 X 24 X 11=5808
	# samples	22	32
	** MAII score	log2(22/1232*10)=-2.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(32/5808*10)=-4.18189764310839 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: GRAMD4 [Title/Abstract] AND TBC1D22A [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	GRAMD4(47033857)-TBC1D22A(47274549), # samples:2 TBC1D22A(47193517)-GRAMD4(47022648), # samples:1 TBC1D22A(47308084)-GRAMD4(47022648), # samples:1
Anticipated loss of major functional domain due to fusion event.	GRAMD4-TBC1D22A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. GRAMD4-TBC1D22A seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across GRAMD4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TBC1D22A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-OL-A66I-01A	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
ChimerDB4	STAD	TCGA-BR-8372-01A	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
ChimerDB4	STAD	TCGA-BR-8372-01A	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
ChimerDB4	STAD	TCGA-CD-A487-01A	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
ChimerDB4	STAD	TCGA-CD-A487	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
ChimerDB4	STAD	TCGA-CG-4441-01A	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
ChimerDB4	STAD	TCGA-CG-4441-01A	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
ChimerDB4	STAD	TCGA-CG-4441-01A	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
ChimerDB4	STAD	TCGA-HU-A4GH-01A	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
ChimerDB4	STAD	TCGA-HU-A4GH	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+

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Fusion Gene ORF analysis for GRAMD4-TBC1D22A

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000361034	ENST00000355704	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
5CDS-intron	ENST00000361034	ENST00000355704	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
5CDS-intron	ENST00000361034	ENST00000355704	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
5CDS-intron	ENST00000361034	ENST00000355704	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
5CDS-intron	ENST00000361034	ENST00000355704	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000361034	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000361034	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000361034	ENST00000380995	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
5CDS-intron	ENST00000361034	ENST00000380995	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
5CDS-intron	ENST00000361034	ENST00000380995	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
5CDS-intron	ENST00000361034	ENST00000380995	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
5CDS-intron	ENST00000361034	ENST00000380995	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000361034	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000361034	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000361034	ENST00000406733	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
5CDS-intron	ENST00000361034	ENST00000406733	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
5CDS-intron	ENST00000361034	ENST00000406733	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
5CDS-intron	ENST00000361034	ENST00000406733	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
5CDS-intron	ENST00000361034	ENST00000406733	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
5CDS-intron	ENST00000361034	ENST00000406733	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
5CDS-intron	ENST00000361034	ENST00000406733	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000361034	ENST00000406733	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000361034	ENST00000406733	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000361034	ENST00000407381	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
5CDS-intron	ENST00000361034	ENST00000407381	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
5CDS-intron	ENST00000361034	ENST00000407381	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
5CDS-intron	ENST00000361034	ENST00000407381	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
5CDS-intron	ENST00000361034	ENST00000407381	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000361034	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000361034	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000361034	ENST00000472791	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
5CDS-intron	ENST00000361034	ENST00000472791	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
5CDS-intron	ENST00000361034	ENST00000472791	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
5CDS-intron	ENST00000361034	ENST00000472791	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
5CDS-intron	ENST00000361034	ENST00000472791	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
5CDS-intron	ENST00000361034	ENST00000472791	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
5CDS-intron	ENST00000361034	ENST00000472791	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000361034	ENST00000472791	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000361034	ENST00000472791	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000406902	ENST00000355704	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
5CDS-intron	ENST00000406902	ENST00000355704	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
5CDS-intron	ENST00000406902	ENST00000355704	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
5CDS-intron	ENST00000406902	ENST00000355704	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
5CDS-intron	ENST00000406902	ENST00000355704	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000406902	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000406902	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000406902	ENST00000380995	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
5CDS-intron	ENST00000406902	ENST00000380995	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
5CDS-intron	ENST00000406902	ENST00000380995	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
5CDS-intron	ENST00000406902	ENST00000380995	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
5CDS-intron	ENST00000406902	ENST00000380995	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000406902	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000406902	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000406902	ENST00000406733	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
5CDS-intron	ENST00000406902	ENST00000406733	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
5CDS-intron	ENST00000406902	ENST00000406733	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
5CDS-intron	ENST00000406902	ENST00000406733	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
5CDS-intron	ENST00000406902	ENST00000406733	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
5CDS-intron	ENST00000406902	ENST00000406733	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
5CDS-intron	ENST00000406902	ENST00000406733	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000406902	ENST00000406733	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000406902	ENST00000406733	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000406902	ENST00000407381	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
5CDS-intron	ENST00000406902	ENST00000407381	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
5CDS-intron	ENST00000406902	ENST00000407381	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
5CDS-intron	ENST00000406902	ENST00000407381	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
5CDS-intron	ENST00000406902	ENST00000407381	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000406902	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000406902	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000406902	ENST00000472791	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
5CDS-intron	ENST00000406902	ENST00000472791	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
5CDS-intron	ENST00000406902	ENST00000472791	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
5CDS-intron	ENST00000406902	ENST00000472791	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
5CDS-intron	ENST00000406902	ENST00000472791	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
5CDS-intron	ENST00000406902	ENST00000472791	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
5CDS-intron	ENST00000406902	ENST00000472791	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000406902	ENST00000472791	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000406902	ENST00000472791	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000490378	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000490378	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000490378	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000490378	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000490378	ENST00000406733	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
5CDS-intron	ENST00000490378	ENST00000406733	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000490378	ENST00000406733	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000490378	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000490378	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
5CDS-intron	ENST00000490378	ENST00000472791	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
5CDS-intron	ENST00000490378	ENST00000472791	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
5CDS-intron	ENST00000490378	ENST00000472791	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
Frame-shift	ENST00000361034	ENST00000337137	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
Frame-shift	ENST00000361034	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
Frame-shift	ENST00000361034	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
Frame-shift	ENST00000361034	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
Frame-shift	ENST00000361034	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
Frame-shift	ENST00000361034	ENST00000355704	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
Frame-shift	ENST00000361034	ENST00000380995	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
Frame-shift	ENST00000361034	ENST00000407381	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
Frame-shift	ENST00000406902	ENST00000337137	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
Frame-shift	ENST00000406902	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
Frame-shift	ENST00000406902	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
Frame-shift	ENST00000406902	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
Frame-shift	ENST00000406902	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
Frame-shift	ENST00000406902	ENST00000355704	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
Frame-shift	ENST00000406902	ENST00000380995	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
Frame-shift	ENST00000406902	ENST00000407381	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
Frame-shift	ENST00000490378	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
Frame-shift	ENST00000490378	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
In-frame	ENST00000361034	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
In-frame	ENST00000361034	ENST00000337137	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
In-frame	ENST00000361034	ENST00000337137	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
In-frame	ENST00000361034	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
In-frame	ENST00000361034	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
In-frame	ENST00000361034	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
In-frame	ENST00000361034	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
In-frame	ENST00000406902	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
In-frame	ENST00000406902	ENST00000337137	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
In-frame	ENST00000406902	ENST00000337137	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
In-frame	ENST00000406902	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
In-frame	ENST00000406902	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
In-frame	ENST00000406902	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
In-frame	ENST00000406902	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
In-frame	ENST00000490378	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
In-frame	ENST00000490378	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
In-frame	ENST00000490378	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
In-frame	ENST00000490378	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
intron-3CDS	ENST00000408031	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
intron-3CDS	ENST00000408031	ENST00000337137	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
intron-3CDS	ENST00000408031	ENST00000337137	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
intron-3CDS	ENST00000408031	ENST00000337137	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
intron-3CDS	ENST00000408031	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
intron-3CDS	ENST00000408031	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
intron-3CDS	ENST00000408031	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
intron-3CDS	ENST00000408031	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
intron-3CDS	ENST00000408031	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
intron-3CDS	ENST00000408031	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
intron-3CDS	ENST00000408031	ENST00000355704	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
intron-3CDS	ENST00000408031	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
intron-3CDS	ENST00000408031	ENST00000380995	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
intron-3CDS	ENST00000408031	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
intron-3CDS	ENST00000408031	ENST00000407381	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
intron-3CDS	ENST00000490378	ENST00000337137	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
intron-3CDS	ENST00000490378	ENST00000337137	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
intron-3CDS	ENST00000490378	ENST00000337137	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
intron-3CDS	ENST00000490378	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
intron-3CDS	ENST00000490378	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
intron-3CDS	ENST00000490378	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
intron-3CDS	ENST00000490378	ENST00000355704	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
intron-3CDS	ENST00000490378	ENST00000380995	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
intron-3CDS	ENST00000490378	ENST00000407381	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
intron-intron	ENST00000408031	ENST00000355704	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
intron-intron	ENST00000408031	ENST00000355704	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
intron-intron	ENST00000408031	ENST00000355704	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
intron-intron	ENST00000408031	ENST00000355704	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
intron-intron	ENST00000408031	ENST00000355704	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000408031	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000408031	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
intron-intron	ENST00000408031	ENST00000380995	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
intron-intron	ENST00000408031	ENST00000380995	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
intron-intron	ENST00000408031	ENST00000380995	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
intron-intron	ENST00000408031	ENST00000380995	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
intron-intron	ENST00000408031	ENST00000380995	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000408031	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000408031	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
intron-intron	ENST00000408031	ENST00000406733	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
intron-intron	ENST00000408031	ENST00000406733	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
intron-intron	ENST00000408031	ENST00000406733	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
intron-intron	ENST00000408031	ENST00000406733	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
intron-intron	ENST00000408031	ENST00000406733	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
intron-intron	ENST00000408031	ENST00000406733	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
intron-intron	ENST00000408031	ENST00000406733	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000408031	ENST00000406733	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000408031	ENST00000406733	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
intron-intron	ENST00000408031	ENST00000407381	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
intron-intron	ENST00000408031	ENST00000407381	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
intron-intron	ENST00000408031	ENST00000407381	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
intron-intron	ENST00000408031	ENST00000407381	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
intron-intron	ENST00000408031	ENST00000407381	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000408031	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000408031	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
intron-intron	ENST00000408031	ENST00000472791	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+
intron-intron	ENST00000408031	ENST00000472791	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
intron-intron	ENST00000408031	ENST00000472791	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
intron-intron	ENST00000408031	ENST00000472791	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
intron-intron	ENST00000408031	ENST00000472791	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
intron-intron	ENST00000408031	ENST00000472791	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
intron-intron	ENST00000408031	ENST00000472791	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000408031	ENST00000472791	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000408031	ENST00000472791	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47393529	+
intron-intron	ENST00000490378	ENST00000355704	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
intron-intron	ENST00000490378	ENST00000355704	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
intron-intron	ENST00000490378	ENST00000355704	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
intron-intron	ENST00000490378	ENST00000355704	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
intron-intron	ENST00000490378	ENST00000355704	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000490378	ENST00000380995	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
intron-intron	ENST00000490378	ENST00000380995	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
intron-intron	ENST00000490378	ENST00000380995	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
intron-intron	ENST00000490378	ENST00000380995	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
intron-intron	ENST00000490378	ENST00000380995	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000490378	ENST00000406733	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
intron-intron	ENST00000490378	ENST00000406733	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
intron-intron	ENST00000490378	ENST00000406733	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
intron-intron	ENST00000490378	ENST00000406733	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
intron-intron	ENST00000490378	ENST00000406733	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
intron-intron	ENST00000490378	ENST00000406733	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000490378	ENST00000407381	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
intron-intron	ENST00000490378	ENST00000407381	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
intron-intron	ENST00000490378	ENST00000407381	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
intron-intron	ENST00000490378	ENST00000407381	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
intron-intron	ENST00000490378	ENST00000407381	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+
intron-intron	ENST00000490378	ENST00000472791	GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274549	+
intron-intron	ENST00000490378	ENST00000472791	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+
intron-intron	ENST00000490378	ENST00000472791	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+
intron-intron	ENST00000490378	ENST00000472791	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370186	+
intron-intron	ENST00000490378	ENST00000472791	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370188	+
intron-intron	ENST00000490378	ENST00000472791	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000406902	GRAMD4	chr22	47069711	+	ENST00000337137	TBC1D22A	chr22	47432966	+	4017	1597	207	1949	580
ENST00000361034	GRAMD4	chr22	47069711	+	ENST00000337137	TBC1D22A	chr22	47432966	+	3843	1423	33	1775	580
ENST00000406902	GRAMD4	chr22	47033857	+	ENST00000337137	TBC1D22A	chr22	47274549	+	3480	496	207	1412	401
ENST00000406902	GRAMD4	chr22	47033857	+	ENST00000380995	TBC1D22A	chr22	47274549	+	975	496	207	974	255
ENST00000406902	GRAMD4	chr22	47033857	+	ENST00000407381	TBC1D22A	chr22	47274549	+	1870	496	207	1412	401
ENST00000406902	GRAMD4	chr22	47033857	+	ENST00000355704	TBC1D22A	chr22	47274549	+	1873	496	207	1412	401
ENST00000361034	GRAMD4	chr22	47033857	+	ENST00000337137	TBC1D22A	chr22	47274549	+	3306	322	33	1238	401
ENST00000361034	GRAMD4	chr22	47033857	+	ENST00000380995	TBC1D22A	chr22	47274549	+	801	322	33	800	255
ENST00000361034	GRAMD4	chr22	47033857	+	ENST00000407381	TBC1D22A	chr22	47274549	+	1696	322	33	1238	401
ENST00000361034	GRAMD4	chr22	47033857	+	ENST00000355704	TBC1D22A	chr22	47274549	+	1699	322	33	1238	401
ENST00000490378	GRAMD4	chr22	47033857	+	ENST00000337137	TBC1D22A	chr22	47274549	+	3177	193	207	1109	300
ENST00000490378	GRAMD4	chr22	47033857	+	ENST00000380995	TBC1D22A	chr22	47274549	+	672	193	207	671	154
ENST00000490378	GRAMD4	chr22	47033857	+	ENST00000407381	TBC1D22A	chr22	47274549	+	1567	193	207	1109	300
ENST00000490378	GRAMD4	chr22	47033857	+	ENST00000355704	TBC1D22A	chr22	47274549	+	1570	193	207	1109	300
ENST00000406902	GRAMD4	chr22	47022858	+	ENST00000337137	TBC1D22A	chr22	47393530	+	2871	375	2076	1312	254
ENST00000361034	GRAMD4	chr22	47022858	+	ENST00000337137	TBC1D22A	chr22	47393530	+	2697	201	1902	1138	254
ENST00000406902	GRAMD4	chr22	47069711	+	ENST00000337137	TBC1D22A	chr22	47432967	+	4017	1597	207	1949	580
ENST00000361034	GRAMD4	chr22	47069711	+	ENST00000337137	TBC1D22A	chr22	47432967	+	3843	1423	33	1775	580

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000406902	ENST00000337137	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+	0.005557567	0.9944424
ENST00000361034	ENST00000337137	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+	0.005368093	0.9946319
ENST00000406902	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+	0.001782151	0.9982179
ENST00000406902	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+	0.00467458	0.99532545
ENST00000406902	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+	0.002847955	0.997152
ENST00000406902	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+	0.002849389	0.9971506
ENST00000361034	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+	0.001732457	0.99826753
ENST00000361034	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+	0.004733778	0.9952662
ENST00000361034	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+	0.003082307	0.9969177
ENST00000361034	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+	0.003088352	0.9969117
ENST00000490378	ENST00000337137	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+	0.002886729	0.9971132
ENST00000490378	ENST00000380995	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+	0.008549713	0.99145025
ENST00000490378	ENST00000407381	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+	0.003744391	0.99625564
ENST00000490378	ENST00000355704	GRAMD4	chr22	47033857	+	TBC1D22A	chr22	47274549	+	0.003774608	0.99622536
ENST00000406902	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+	0.004931498	0.99506855
ENST00000361034	ENST00000337137	GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393530	+	0.004476626	0.99552333
ENST00000406902	ENST00000337137	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+	0.005557567	0.9944424
ENST00000361034	ENST00000337137	GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432967	+	0.005368093	0.9946319

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Fusion Genomic Features for GRAMD4-TBC1D22A

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
GRAMD4	chr22	47033855	+	TBC1D22A	chr22	47393529	+	0.000411439	0.99958855
GRAMD4	chr22	47033855	+	TBC1D22A	chr22	47393529	+	0.000411439	0.99958855
GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274548	+	6.73E-05	0.99993265
GRAMD4	chr22	47033855	+	TBC1D22A	chr22	47274548	+	1.06E-05	0.9999894
GRAMD4	chr22	47033855	+	TBC1D22A	chr22	47274548	+	1.06E-05	0.9999894
GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+	4.01E-07	0.99999964
GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+	4.01E-07	0.99999964
GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393529	+	1.17E-07	0.9999999
GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370185	+	2.75E-12	1
GRAMD4	chr22	47033855	+	TBC1D22A	chr22	47393529	+	0.000411439	0.99958855
GRAMD4	chr22	47033855	+	TBC1D22A	chr22	47393529	+	0.000411439	0.99958855
GRAMD4	chr22	47060014	+	TBC1D22A	chr22	47274548	+	6.73E-05	0.99993265
GRAMD4	chr22	47033855	+	TBC1D22A	chr22	47274548	+	1.06E-05	0.9999894
GRAMD4	chr22	47033855	+	TBC1D22A	chr22	47274548	+	1.06E-05	0.9999894
GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+	4.01E-07	0.99999964
GRAMD4	chr22	47069711	+	TBC1D22A	chr22	47432966	+	4.01E-07	0.99999964
GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47393529	+	1.17E-07	0.9999999
GRAMD4	chr22	47022858	+	TBC1D22A	chr22	47370185	+	2.75E-12	1

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GRAMD4-TBC1D22A

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:47033857/chr22:47274549)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
GRAMD4 Q6IC98	.
FUNCTION: Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53 (PubMed:15565177). Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response (By similarity). {ECO:0000250\|UniProtKB:Q8CB44, ECO:0000269\|PubMed:15565177}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000361034

83_143

461

579.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000406902

83_143

461

579.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000361034

83_143

461

579.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000406902

83_143

461

579.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000361034

240_260

461

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000361034

334_354

461

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000361034

356_376

461

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000406902

240_260

461

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000406902

334_354

461

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000406902

356_376

461

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000361034

240_260

461

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000361034

334_354

461

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000361034

356_376

461

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000406902

240_260

461

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000406902

334_354

461

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000406902

356_376

461

579.0

Transmembrane

Helical

Tgene

TBC1D22A

chr22:47022858

chr22:47393530

ENST00000380995

222_446

325.0

Domain

Rab-GAP TBC

Tgene

TBC1D22A

chr22:47033857

chr22:47274549

ENST00000337137

222_446

212

518.0

Domain

Rab-GAP TBC

Tgene

TBC1D22A

chr22:47033857

chr22:47274549

ENST00000355704

222_446

134

440.0

Domain

Rab-GAP TBC

Tgene

TBC1D22A

chr22:47033857

chr22:47274549

ENST00000380995

222_446

165

325.0

Domain

Rab-GAP TBC

Tgene

TBC1D22A

chr22:47069711

chr22:47432966

ENST00000380995

222_446

325.0

Domain

Rab-GAP TBC

Tgene

TBC1D22A

chr22:47069711

chr22:47432967

ENST00000380995

222_446

325.0

Domain

Rab-GAP TBC

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000361034

83_143

579.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000406902

83_143

579.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000408031

83_143

102.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000361034

83_143

579.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000406902

83_143

579.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000408031

83_143

102.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000408031

83_143

102.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000408031

83_143

102.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000361034

445_523

579.0

Domain

Note=GRAM

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000406902

445_523

579.0

Domain

Note=GRAM

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000408031

445_523

102.0

Domain

Note=GRAM

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000361034

445_523

579.0

Domain

Note=GRAM

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000406902

445_523

579.0

Domain

Note=GRAM

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000408031

445_523

102.0

Domain

Note=GRAM

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000361034

445_523

461

579.0

Domain

Note=GRAM

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000406902

445_523

461

579.0

Domain

Note=GRAM

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000408031

445_523

102.0

Domain

Note=GRAM

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000361034

445_523

461

579.0

Domain

Note=GRAM

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000406902

445_523

461

579.0

Domain

Note=GRAM

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000408031

445_523

102.0

Domain

Note=GRAM

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000361034

240_260

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000361034

334_354

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000361034

356_376

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000406902

240_260

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000406902

334_354

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000406902

356_376

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000408031

240_260

102.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000408031

334_354

102.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47022858

chr22:47393530

ENST00000408031

356_376

102.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000361034

240_260

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000361034

334_354

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000361034

356_376

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000406902

240_260

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000406902

334_354

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000406902

356_376

579.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000408031

240_260

102.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000408031

334_354

102.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47033857

chr22:47274549

ENST00000408031

356_376

102.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000408031

240_260

102.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000408031

334_354

102.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432966

ENST00000408031

356_376

102.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000408031

240_260

102.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000408031

334_354

102.0

Transmembrane

Helical

Hgene

GRAMD4

chr22:47069711

chr22:47432967

ENST00000408031

356_376

102.0

Transmembrane

Helical

Tgene

TBC1D22A

chr22:47022858

chr22:47393530

ENST00000337137

222_446

375

518.0

Domain

Rab-GAP TBC

Tgene

TBC1D22A

chr22:47022858

chr22:47393530

ENST00000355704

222_446

297

440.0

Domain

Rab-GAP TBC

Tgene

TBC1D22A

chr22:47069711

chr22:47432966

ENST00000337137

222_446

400

518.0

Domain

Rab-GAP TBC

Tgene

TBC1D22A

chr22:47069711

chr22:47432966

ENST00000355704

222_446

322

440.0

Domain

Rab-GAP TBC

Tgene

TBC1D22A

chr22:47069711

chr22:47432967

ENST00000337137

222_446

400

518.0

Domain

Rab-GAP TBC

Tgene

TBC1D22A

chr22:47069711

chr22:47432967

ENST00000355704

222_446

322

440.0

Domain

Rab-GAP TBC

Top

Fusion Gene Sequence for GRAMD4-TBC1D22A

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>34605_34605_1_GRAMD4-TBC1D22A_GRAMD4_chr22_47022858_ENST00000361034_TBC1D22A_chr22_47393530_ENST00000337137_length(transcript)=2697nt_BP=201nt
CGTCATGTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGAC
TTCCTCGATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGAC
AGCGAGGAGCTGAGGGACCCTGACAACTACACCTTTGCCCAACCTGGGATTCAAATGAAAGTGAAAATGTTAGAAGAACTCGTGAGCCGG
ATTGATGAGCAAGTGCACCGGCACCTGGACCAACACGAAGTGAGATACCTGCAGTTTGCCTTCCGCTGGATGAACAACCTGCTGATGAGG
GAGGTGCCCCTGCGTTGTACCATCCGCCTGTGGGACACCTACCAGTCTGAACCGGACGGCTTTTCTCATTTCCACTTGTACGTGTGCGCT
GCTTTTCTCGTGAGATGGAGGAAGGAAATACTAGAAGAAAAAGATTTTCAAGAGCTGCTGCTCTTCCTCCAGAACCTGCCCACAGCCCAC
TGGGATGATGAGGACATCAGCCTGTTGCTGGCCGAGGCCTACCGCCTCAAGTTTGCTTTTGCCGACGCCCCCAATCACTACAAGAAATGA
GCCCAGGCCCACCCGCAGCTGGCCTCACTGTCCCGGGTGGCGCGCCCCACCTGCCTGGCTGGTGGTAGGCCCCTGTGAGCTGGTCCCGGG
CTGCTAAAAGGCCTTGTGAGGTGGCCCCACCCTCCAGGGGAGCTGGTGAAGATGGGCCACAGACCTGGTCTAGGGCTGACAAAGACAGGG
ACAGCCTTTGTTTTCTGAGATACCAAAGAGAGCCAGGGGAGGGCCCCGGGTTCGGCGGCCAGAGGCAGGTCAGGGGTCCCCTCTCCCTCT
CCCTGCAATGTCCTTGCCAAATGACTGCCTCGTGCTGCCCCTAGTCCGGGGCAGCCTAGGAGGCCGACCCTCTTTGGAGTCCTGCTGTCT
GGGTGCCAGGGCCGGAACGAGGTAGTGGCCATCTCATACCTACTCTGAAATGCAAAACTTCTATTCTGTTGAGTGAAAGAATAAAATGTA
GACAAAATCTAGACCGAGACGTTGCGCTGACCCGGGGTCTCTGTGCCGCGAGGTCCCCTCACAGCTGTATTTCACTGCTGCTGGCCCTTT
CCCTCCGTGTGTTTTCCTGCTTGCTTGGTTTAAACGTGGCTGGGAAGCTGAAGGCTGGAGTCCAAGCCGTGAGCCCGCCGAGTGCCTGGG
AGGCCGTGGGACCAAAGGCTGGGAGCAGAGGGAGGCCTCGCCATCGCCTTACTTTCCACCTTGAACCTCTTTTACAAGAGAGAAACCCCC
ACCTCCCTGAGGTCCAGGGCCAAGTGGCCCCGCCACGCAGGTAGGCGCCGGCCTCAGCCAGAGCCCCTGGAGGCCCACCCAGGCTGTCGG
GCCATGTTGGGCTGGCAGACGGGCAGGGGGTCGCGTCCCTGTCATCAAAGCCCTGAACCACAGTGCTCTTCTCACCGCAGCCTGGAAGCG
GAATGAGCTTTTGGAGACTTCCTGGGACTTGCTGTCCTTGTCCAGGTCTGCCAGGTGTAGGGGAGGTGTGACTGGTTCCATCATGGACCG
GTTCCTCCATGGACCGGTTCCTCCGTGGACCGGTTCCGCCATGGACCGGTTCCGCCATGGACCACTCCTGCCCTGGACCACTCCTGCCCT
GGACCGGTTCTGCCGTGGACTGGTTCCCGCCGTGGACCAGTTCCCGCTGTATACTGGTTCTGCCCTGGACTGGTTCCCGCTGTGGACTGG
TTCCTTGGGGCTCTAAGTGCGGAAGGGCCCAGAGCTGGTCCCTGCCCAGCGCCCTGCTAGGGCTGTGTCCTTGGCTCCAGGGGCCTTGGG
ACTGGCTTCCCAGCGTTCCCTCGGTGTGTCACAGGCTGCATGACCCCTGGAATGCGGGCAGGGCCACAGCCACAGTCTGTCTGATCCCTG
AGCCCAGGACAGGCTCACGTCCTCAGCGACCCACTGGTGACTGACTTCCCAGACTCTCCTCTGTCCCTCAGGAGCAGCCGTGTCCTCTCC
CAGGCCCTAGGACACTGCCAGAGACTGTGGGACATACAGGCATAAGTGATGTGTGTGTTTCTGCTTCTGTTTTAAAAATCCAGGGTCATT
ACACACAGCATGGAAATTAGCACAAAATGCTGTGCAAACGTCAGATGCTCCCAAACCAGCAAAGGGATGGGCTTGCTTCACATCAGATGC
GGGCACGCCTTACCCCTGCCTTCCGTGTCCCCACCCCAGGGTCAAGGGTTCCTCAGACCAGCCATGCCTCCTCCTCCTGCCGCCTCCTTT
TCTAGATGGGGAGGGGATTCCGTCACAAGAAGAGCCGCCCCTCGGCCGTGTGCAGGAAGCCCCATGTCGCTTTGCCGAGATCAGCCCTGG
GAGGATCCCCTTCTCCAGCTCAGATCATGCCGTGTGGCCAGAAGGCTGCGGACACAACTGACCTGCTTCTCGAGGTGGTTGATGTTTTAA
ACAGGAAGCTCCACGGAGTTCAGCCCTGTGTGCATTTCCTCATGTATGTAAACGCCAAGACTGAATGTGAGAGGTGTTGGCCGCGGGCCT

>34605_34605_1_GRAMD4-TBC1D22A_GRAMD4_chr22_47022858_ENST00000361034_TBC1D22A_chr22_47393530_ENST00000337137_length(amino acids)=254AA_BP=56
MGSQSQGPWSQGHSPSRALGRDQLWALPHLEPQGTSPQREPVQGRTSIQRELVHGGNQSTAEPVQGRSGPGQEWSMAEPVHGGTGPRRNR
SMEEPVHDGTSHTSPTPGRPGQGQQVPGSLQKLIPLPGCGEKSTVVQGFDDRDATPCPSASPTWPDSLGGPPGALAEAGAYLRGGATWPW

--------------------------------------------------------------
>34605_34605_2_GRAMD4-TBC1D22A_GRAMD4_chr22_47022858_ENST00000406902_TBC1D22A_chr22_47393530_ENST00000337137_length(transcript)=2871nt_BP=375nt
CTCCAGGCTCCAGGGCAGCAGACACCACCCTCTCCGTGCCTGCTGGTGTTGGGCGGCTTGGAGGCTATGGTTCCTGGGTCCTCGTAGCAC
ATCCTGGTTCTGGGCCAGGACCTGAAGGAGCCACAGTGAAAGAGTGTTTCTGGATGTATCTGAGACAGACGGAGGGAACCCGAGCGTCAT
GTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGACTTCCTC
GATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGACAGCGAG
GAGCTGAGGGACCCTGACAACTACACCTTTGCCCAACCTGGGATTCAAATGAAAGTGAAAATGTTAGAAGAACTCGTGAGCCGGATTGAT
GAGCAAGTGCACCGGCACCTGGACCAACACGAAGTGAGATACCTGCAGTTTGCCTTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTG
CCCCTGCGTTGTACCATCCGCCTGTGGGACACCTACCAGTCTGAACCGGACGGCTTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTT
CTCGTGAGATGGAGGAAGGAAATACTAGAAGAAAAAGATTTTCAAGAGCTGCTGCTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGAT
GATGAGGACATCAGCCTGTTGCTGGCCGAGGCCTACCGCCTCAAGTTTGCTTTTGCCGACGCCCCCAATCACTACAAGAAATGAGCCCAG
GCCCACCCGCAGCTGGCCTCACTGTCCCGGGTGGCGCGCCCCACCTGCCTGGCTGGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTA
AAAGGCCTTGTGAGGTGGCCCCACCCTCCAGGGGAGCTGGTGAAGATGGGCCACAGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCC
TTTGTTTTCTGAGATACCAAAGAGAGCCAGGGGAGGGCCCCGGGTTCGGCGGCCAGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGC
AATGTCCTTGCCAAATGACTGCCTCGTGCTGCCCCTAGTCCGGGGCAGCCTAGGAGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGC
CAGGGCCGGAACGAGGTAGTGGCCATCTCATACCTACTCTGAAATGCAAAACTTCTATTCTGTTGAGTGAAAGAATAAAATGTAGACAAA
ATCTAGACCGAGACGTTGCGCTGACCCGGGGTCTCTGTGCCGCGAGGTCCCCTCACAGCTGTATTTCACTGCTGCTGGCCCTTTCCCTCC
GTGTGTTTTCCTGCTTGCTTGGTTTAAACGTGGCTGGGAAGCTGAAGGCTGGAGTCCAAGCCGTGAGCCCGCCGAGTGCCTGGGAGGCCG
TGGGACCAAAGGCTGGGAGCAGAGGGAGGCCTCGCCATCGCCTTACTTTCCACCTTGAACCTCTTTTACAAGAGAGAAACCCCCACCTCC
CTGAGGTCCAGGGCCAAGTGGCCCCGCCACGCAGGTAGGCGCCGGCCTCAGCCAGAGCCCCTGGAGGCCCACCCAGGCTGTCGGGCCATG
TTGGGCTGGCAGACGGGCAGGGGGTCGCGTCCCTGTCATCAAAGCCCTGAACCACAGTGCTCTTCTCACCGCAGCCTGGAAGCGGAATGA
GCTTTTGGAGACTTCCTGGGACTTGCTGTCCTTGTCCAGGTCTGCCAGGTGTAGGGGAGGTGTGACTGGTTCCATCATGGACCGGTTCCT
CCATGGACCGGTTCCTCCGTGGACCGGTTCCGCCATGGACCGGTTCCGCCATGGACCACTCCTGCCCTGGACCACTCCTGCCCTGGACCG
GTTCTGCCGTGGACTGGTTCCCGCCGTGGACCAGTTCCCGCTGTATACTGGTTCTGCCCTGGACTGGTTCCCGCTGTGGACTGGTTCCTT
GGGGCTCTAAGTGCGGAAGGGCCCAGAGCTGGTCCCTGCCCAGCGCCCTGCTAGGGCTGTGTCCTTGGCTCCAGGGGCCTTGGGACTGGC
TTCCCAGCGTTCCCTCGGTGTGTCACAGGCTGCATGACCCCTGGAATGCGGGCAGGGCCACAGCCACAGTCTGTCTGATCCCTGAGCCCA
GGACAGGCTCACGTCCTCAGCGACCCACTGGTGACTGACTTCCCAGACTCTCCTCTGTCCCTCAGGAGCAGCCGTGTCCTCTCCCAGGCC
CTAGGACACTGCCAGAGACTGTGGGACATACAGGCATAAGTGATGTGTGTGTTTCTGCTTCTGTTTTAAAAATCCAGGGTCATTACACAC
AGCATGGAAATTAGCACAAAATGCTGTGCAAACGTCAGATGCTCCCAAACCAGCAAAGGGATGGGCTTGCTTCACATCAGATGCGGGCAC
GCCTTACCCCTGCCTTCCGTGTCCCCACCCCAGGGTCAAGGGTTCCTCAGACCAGCCATGCCTCCTCCTCCTGCCGCCTCCTTTTCTAGA
TGGGGAGGGGATTCCGTCACAAGAAGAGCCGCCCCTCGGCCGTGTGCAGGAAGCCCCATGTCGCTTTGCCGAGATCAGCCCTGGGAGGAT
CCCCTTCTCCAGCTCAGATCATGCCGTGTGGCCAGAAGGCTGCGGACACAACTGACCTGCTTCTCGAGGTGGTTGATGTTTTAAACAGGA
AGCTCCACGGAGTTCAGCCCTGTGTGCATTTCCTCATGTATGTAAACGCCAAGACTGAATGTGAGAGGTGTTGGCCGCGGGCCTTAAGTC

>34605_34605_2_GRAMD4-TBC1D22A_GRAMD4_chr22_47022858_ENST00000406902_TBC1D22A_chr22_47393530_ENST00000337137_length(amino acids)=254AA_BP=56
MGSQSQGPWSQGHSPSRALGRDQLWALPHLEPQGTSPQREPVQGRTSIQRELVHGGNQSTAEPVQGRSGPGQEWSMAEPVHGGTGPRRNR
SMEEPVHDGTSHTSPTPGRPGQGQQVPGSLQKLIPLPGCGEKSTVVQGFDDRDATPCPSASPTWPDSLGGPPGALAEAGAYLRGGATWPW

--------------------------------------------------------------
>34605_34605_3_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000361034_TBC1D22A_chr22_47274549_ENST00000337137_length(transcript)=3306nt_BP=322nt
CGTCATGTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGAC
TTCCTCGATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGAC
AGCGAGGAGCTGAGGGACCCTGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTG
AATGAGATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAG
CCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAA
GAATATTTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCT
CGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCC
AGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAGAGGCAGAGGAGGTGGACACG
GTGGACGTCTCCGGCGTGCCCGCAGAGGTGCTGTGCAACATCGAGGCCGACACCTACTGGTGCATGAGCAAGCTGCTGGATGGCATTCAG
GACAACTACACCTTTGCCCAACCTGGGATTCAAATGAAAGTGAAAATGTTAGAAGAACTCGTGAGCCGGATTGATGAGCAAGTGCACCGG
CACCTGGACCAACACGAAGTGAGATACCTGCAGTTTGCCTTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTGCCCCTGCGTTGTACC
ATCCGCCTGTGGGACACCTACCAGTCTGAACCGGACGGCTTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTTCTCGTGAGATGGAGG
AAGGAAATACTAGAAGAAAAAGATTTTCAAGAGCTGCTGCTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGATGATGAGGACATCAGC
CTGTTGCTGGCCGAGGCCTACCGCCTCAAGTTTGCTTTTGCCGACGCCCCCAATCACTACAAGAAATGAGCCCAGGCCCACCCGCAGCTG
GCCTCACTGTCCCGGGTGGCGCGCCCCACCTGCCTGGCTGGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTAAAAGGCCTTGTGAGG
TGGCCCCACCCTCCAGGGGAGCTGGTGAAGATGGGCCACAGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCCTTTGTTTTCTGAGAT
ACCAAAGAGAGCCAGGGGAGGGCCCCGGGTTCGGCGGCCAGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGCAATGTCCTTGCCAAA
TGACTGCCTCGTGCTGCCCCTAGTCCGGGGCAGCCTAGGAGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGCCAGGGCCGGAACGAG
GTAGTGGCCATCTCATACCTACTCTGAAATGCAAAACTTCTATTCTGTTGAGTGAAAGAATAAAATGTAGACAAAATCTAGACCGAGACG
TTGCGCTGACCCGGGGTCTCTGTGCCGCGAGGTCCCCTCACAGCTGTATTTCACTGCTGCTGGCCCTTTCCCTCCGTGTGTTTTCCTGCT
TGCTTGGTTTAAACGTGGCTGGGAAGCTGAAGGCTGGAGTCCAAGCCGTGAGCCCGCCGAGTGCCTGGGAGGCCGTGGGACCAAAGGCTG
GGAGCAGAGGGAGGCCTCGCCATCGCCTTACTTTCCACCTTGAACCTCTTTTACAAGAGAGAAACCCCCACCTCCCTGAGGTCCAGGGCC
AAGTGGCCCCGCCACGCAGGTAGGCGCCGGCCTCAGCCAGAGCCCCTGGAGGCCCACCCAGGCTGTCGGGCCATGTTGGGCTGGCAGACG
GGCAGGGGGTCGCGTCCCTGTCATCAAAGCCCTGAACCACAGTGCTCTTCTCACCGCAGCCTGGAAGCGGAATGAGCTTTTGGAGACTTC
CTGGGACTTGCTGTCCTTGTCCAGGTCTGCCAGGTGTAGGGGAGGTGTGACTGGTTCCATCATGGACCGGTTCCTCCATGGACCGGTTCC
TCCGTGGACCGGTTCCGCCATGGACCGGTTCCGCCATGGACCACTCCTGCCCTGGACCACTCCTGCCCTGGACCGGTTCTGCCGTGGACT
GGTTCCCGCCGTGGACCAGTTCCCGCTGTATACTGGTTCTGCCCTGGACTGGTTCCCGCTGTGGACTGGTTCCTTGGGGCTCTAAGTGCG
GAAGGGCCCAGAGCTGGTCCCTGCCCAGCGCCCTGCTAGGGCTGTGTCCTTGGCTCCAGGGGCCTTGGGACTGGCTTCCCAGCGTTCCCT
CGGTGTGTCACAGGCTGCATGACCCCTGGAATGCGGGCAGGGCCACAGCCACAGTCTGTCTGATCCCTGAGCCCAGGACAGGCTCACGTC
CTCAGCGACCCACTGGTGACTGACTTCCCAGACTCTCCTCTGTCCCTCAGGAGCAGCCGTGTCCTCTCCCAGGCCCTAGGACACTGCCAG
AGACTGTGGGACATACAGGCATAAGTGATGTGTGTGTTTCTGCTTCTGTTTTAAAAATCCAGGGTCATTACACACAGCATGGAAATTAGC
ACAAAATGCTGTGCAAACGTCAGATGCTCCCAAACCAGCAAAGGGATGGGCTTGCTTCACATCAGATGCGGGCACGCCTTACCCCTGCCT
TCCGTGTCCCCACCCCAGGGTCAAGGGTTCCTCAGACCAGCCATGCCTCCTCCTCCTGCCGCCTCCTTTTCTAGATGGGGAGGGGATTCC
GTCACAAGAAGAGCCGCCCCTCGGCCGTGTGCAGGAAGCCCCATGTCGCTTTGCCGAGATCAGCCCTGGGAGGATCCCCTTCTCCAGCTC
AGATCATGCCGTGTGGCCAGAAGGCTGCGGACACAACTGACCTGCTTCTCGAGGTGGTTGATGTTTTAAACAGGAAGCTCCACGGAGTTC
AGCCCTGTGTGCATTTCCTCATGTATGTAAACGCCAAGACTGAATGTGAGAGGTGTTGGCCGCGGGCCTTAAGTCTGAGCAGATCCATCT

>34605_34605_3_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000361034_TBC1D22A_chr22_47274549_ENST00000337137_length(amino acids)=401AA_BP=1
MNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIAL
LEKHFLQELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQP
KVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQ
MKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQE

--------------------------------------------------------------
>34605_34605_4_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000361034_TBC1D22A_chr22_47274549_ENST00000355704_length(transcript)=1699nt_BP=322nt
CGTCATGTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGAC
TTCCTCGATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGAC
AGCGAGGAGCTGAGGGACCCTGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTG
AATGAGATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAG
CCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAA
GAATATTTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCT
CGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCC
AGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAGAGGCAGAGGAGGTGGACACG
GTGGACGTCTCCGGCGTGCCCGCAGAGGTGCTGTGCAACATCGAGGCCGACACCTACTGGTGCATGAGCAAGCTGCTGGATGGCATTCAG
GACAACTACACCTTTGCCCAACCTGGGATTCAAATGAAAGTGAAAATGTTAGAAGAACTCGTGAGCCGGATTGATGAGCAAGTGCACCGG
CACCTGGACCAACACGAAGTGAGATACCTGCAGTTTGCCTTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTGCCCCTGCGTTGTACC
ATCCGCCTGTGGGACACCTACCAGTCTGAACCGGACGGCTTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTTCTCGTGAGATGGAGG
AAGGAAATACTAGAAGAAAAAGATTTTCAAGAGCTGCTGCTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGATGATGAGGACATCAGC
CTGTTGCTGGCCGAGGCCTACCGCCTCAAGTTTGCTTTTGCCGACGCCCCCAATCACTACAAGAAATGAGCCCAGGCCCACCCGCAGCTG
GCCTCACTGTCCCGGGTGGCGCGCCCCACCTGCCTGGCTGGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTAAAAGGCCTTGTGAGG
TGGCCCCACCCTCCAGGGGAGCTGGTGAAGATGGGCCACAGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCCTTTGTTTTCTGAGAT
ACCAAAGAGAGCCAGGGGAGGGCCCCGGGTTCGGCGGCCAGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGCAATGTCCTTGCCAAA
TGACTGCCTCGTGCTGCCCCTAGTCCGGGGCAGCCTAGGAGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGCCAGGGCCGGAACGAG

>34605_34605_4_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000361034_TBC1D22A_chr22_47274549_ENST00000355704_length(amino acids)=401AA_BP=1
MNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIAL
LEKHFLQELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQP
KVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQ
MKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQE

--------------------------------------------------------------
>34605_34605_5_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000361034_TBC1D22A_chr22_47274549_ENST00000380995_length(transcript)=801nt_BP=322nt
CGTCATGTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGAC
TTCCTCGATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGAC
AGCGAGGAGCTGAGGGACCCTGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTG
AATGAGATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAG
CCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAA
GAATATTTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCT
CGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCC
AGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAGCCTTTCCAGGTTGTGGTCGG

>34605_34605_5_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000361034_TBC1D22A_chr22_47274549_ENST00000380995_length(amino acids)=255AA_BP=1
MNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIAL
LEKHFLQELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQP

--------------------------------------------------------------
>34605_34605_6_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000361034_TBC1D22A_chr22_47274549_ENST00000407381_length(transcript)=1696nt_BP=322nt
CGTCATGTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGAC
TTCCTCGATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGAC
AGCGAGGAGCTGAGGGACCCTGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTG
AATGAGATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAG
CCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAA
GAATATTTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCT
CGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCC
AGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAGAGGCAGAGGAGGTGGACACG
GTGGACGTCTCCGGCGTGCCCGCAGAGGTGCTGTGCAACATCGAGGCCGACACCTACTGGTGCATGAGCAAGCTGCTGGATGGCATTCAG
GACAACTACACCTTTGCCCAACCTGGGATTCAAATGAAAGTGAAAATGTTAGAAGAACTCGTGAGCCGGATTGATGAGCAAGTGCACCGG
CACCTGGACCAACACGAAGTGAGATACCTGCAGTTTGCCTTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTGCCCCTGCGTTGTACC
ATCCGCCTGTGGGACACCTACCAGTCTGAACCGGACGGCTTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTTCTCGTGAGATGGAGG
AAGGAAATACTAGAAGAAAAAGATTTTCAAGAGCTGCTGCTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGATGATGAGGACATCAGC
CTGTTGCTGGCCGAGGCCTACCGCCTCAAGTTTGCTTTTGCCGACGCCCCCAATCACTACAAGAAATGAGCCCAGGCCCACCCGCAGCTG
GCCTCACTGTCCCGGGTGGCGCGCCCCACCTGCCTGGCTGGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTAAAAGGCCTTGTGAGG
TGGCCCCACCCTCCAGGGGAGCTGGTGAAGATGGGCCACAGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCCTTTGTTTTCTGAGAT
ACCAAAGAGAGCCAGGGGAGGGCCCCGGGTTCGGCGGCCAGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGCAATGTCCTTGCCAAA
TGACTGCCTCGTGCTGCCCCTAGTCCGGGGCAGCCTAGGAGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGCCAGGGCCGGAACGAG

>34605_34605_6_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000361034_TBC1D22A_chr22_47274549_ENST00000407381_length(amino acids)=401AA_BP=1
MNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIAL
LEKHFLQELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQP
KVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQ
MKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQE

--------------------------------------------------------------
>34605_34605_7_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000406902_TBC1D22A_chr22_47274549_ENST00000337137_length(transcript)=3480nt_BP=496nt
CTCCAGGCTCCAGGGCAGCAGACACCACCCTCTCCGTGCCTGCTGGTGTTGGGCGGCTTGGAGGCTATGGTTCCTGGGTCCTCGTAGCAC
ATCCTGGTTCTGGGCCAGGACCTGAAGGAGCCACAGTGAAAGAGTGTTTCTGGATGTATCTGAGACAGACGGAGGGAACCCGAGCGTCAT
GTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGACTTCCTC
GATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGACAGCGAG
GAGCTGAGGGACCCTGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTGAATGAG
ATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAGCCAGTG
CGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAAGAATAT
TTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCTCGCATG
AGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCCAGTGGA
TACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAGAGGCAGAGGAGGTGGACACGGTGGAC
GTCTCCGGCGTGCCCGCAGAGGTGCTGTGCAACATCGAGGCCGACACCTACTGGTGCATGAGCAAGCTGCTGGATGGCATTCAGGACAAC
TACACCTTTGCCCAACCTGGGATTCAAATGAAAGTGAAAATGTTAGAAGAACTCGTGAGCCGGATTGATGAGCAAGTGCACCGGCACCTG
GACCAACACGAAGTGAGATACCTGCAGTTTGCCTTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTGCCCCTGCGTTGTACCATCCGC
CTGTGGGACACCTACCAGTCTGAACCGGACGGCTTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTTCTCGTGAGATGGAGGAAGGAA
ATACTAGAAGAAAAAGATTTTCAAGAGCTGCTGCTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGATGATGAGGACATCAGCCTGTTG
CTGGCCGAGGCCTACCGCCTCAAGTTTGCTTTTGCCGACGCCCCCAATCACTACAAGAAATGAGCCCAGGCCCACCCGCAGCTGGCCTCA
CTGTCCCGGGTGGCGCGCCCCACCTGCCTGGCTGGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTAAAAGGCCTTGTGAGGTGGCCC
CACCCTCCAGGGGAGCTGGTGAAGATGGGCCACAGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCCTTTGTTTTCTGAGATACCAAA
GAGAGCCAGGGGAGGGCCCCGGGTTCGGCGGCCAGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGCAATGTCCTTGCCAAATGACTG
CCTCGTGCTGCCCCTAGTCCGGGGCAGCCTAGGAGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGCCAGGGCCGGAACGAGGTAGTG
GCCATCTCATACCTACTCTGAAATGCAAAACTTCTATTCTGTTGAGTGAAAGAATAAAATGTAGACAAAATCTAGACCGAGACGTTGCGC
TGACCCGGGGTCTCTGTGCCGCGAGGTCCCCTCACAGCTGTATTTCACTGCTGCTGGCCCTTTCCCTCCGTGTGTTTTCCTGCTTGCTTG
GTTTAAACGTGGCTGGGAAGCTGAAGGCTGGAGTCCAAGCCGTGAGCCCGCCGAGTGCCTGGGAGGCCGTGGGACCAAAGGCTGGGAGCA
GAGGGAGGCCTCGCCATCGCCTTACTTTCCACCTTGAACCTCTTTTACAAGAGAGAAACCCCCACCTCCCTGAGGTCCAGGGCCAAGTGG
CCCCGCCACGCAGGTAGGCGCCGGCCTCAGCCAGAGCCCCTGGAGGCCCACCCAGGCTGTCGGGCCATGTTGGGCTGGCAGACGGGCAGG
GGGTCGCGTCCCTGTCATCAAAGCCCTGAACCACAGTGCTCTTCTCACCGCAGCCTGGAAGCGGAATGAGCTTTTGGAGACTTCCTGGGA
CTTGCTGTCCTTGTCCAGGTCTGCCAGGTGTAGGGGAGGTGTGACTGGTTCCATCATGGACCGGTTCCTCCATGGACCGGTTCCTCCGTG
GACCGGTTCCGCCATGGACCGGTTCCGCCATGGACCACTCCTGCCCTGGACCACTCCTGCCCTGGACCGGTTCTGCCGTGGACTGGTTCC
CGCCGTGGACCAGTTCCCGCTGTATACTGGTTCTGCCCTGGACTGGTTCCCGCTGTGGACTGGTTCCTTGGGGCTCTAAGTGCGGAAGGG
CCCAGAGCTGGTCCCTGCCCAGCGCCCTGCTAGGGCTGTGTCCTTGGCTCCAGGGGCCTTGGGACTGGCTTCCCAGCGTTCCCTCGGTGT
GTCACAGGCTGCATGACCCCTGGAATGCGGGCAGGGCCACAGCCACAGTCTGTCTGATCCCTGAGCCCAGGACAGGCTCACGTCCTCAGC
GACCCACTGGTGACTGACTTCCCAGACTCTCCTCTGTCCCTCAGGAGCAGCCGTGTCCTCTCCCAGGCCCTAGGACACTGCCAGAGACTG
TGGGACATACAGGCATAAGTGATGTGTGTGTTTCTGCTTCTGTTTTAAAAATCCAGGGTCATTACACACAGCATGGAAATTAGCACAAAA
TGCTGTGCAAACGTCAGATGCTCCCAAACCAGCAAAGGGATGGGCTTGCTTCACATCAGATGCGGGCACGCCTTACCCCTGCCTTCCGTG
TCCCCACCCCAGGGTCAAGGGTTCCTCAGACCAGCCATGCCTCCTCCTCCTGCCGCCTCCTTTTCTAGATGGGGAGGGGATTCCGTCACA
AGAAGAGCCGCCCCTCGGCCGTGTGCAGGAAGCCCCATGTCGCTTTGCCGAGATCAGCCCTGGGAGGATCCCCTTCTCCAGCTCAGATCA
TGCCGTGTGGCCAGAAGGCTGCGGACACAACTGACCTGCTTCTCGAGGTGGTTGATGTTTTAAACAGGAAGCTCCACGGAGTTCAGCCCT
GTGTGCATTTCCTCATGTATGTAAACGCCAAGACTGAATGTGAGAGGTGTTGGCCGCGGGCCTTAAGTCTGAGCAGATCCATCTGGAATG

>34605_34605_7_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000406902_TBC1D22A_chr22_47274549_ENST00000337137_length(amino acids)=401AA_BP=1
MNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIAL
LEKHFLQELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQP
KVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQ
MKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQE

--------------------------------------------------------------
>34605_34605_8_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000406902_TBC1D22A_chr22_47274549_ENST00000355704_length(transcript)=1873nt_BP=496nt
CTCCAGGCTCCAGGGCAGCAGACACCACCCTCTCCGTGCCTGCTGGTGTTGGGCGGCTTGGAGGCTATGGTTCCTGGGTCCTCGTAGCAC
ATCCTGGTTCTGGGCCAGGACCTGAAGGAGCCACAGTGAAAGAGTGTTTCTGGATGTATCTGAGACAGACGGAGGGAACCCGAGCGTCAT
GTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGACTTCCTC
GATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGACAGCGAG
GAGCTGAGGGACCCTGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTGAATGAG
ATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAGCCAGTG
CGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAAGAATAT
TTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCTCGCATG
AGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCCAGTGGA
TACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAGAGGCAGAGGAGGTGGACACGGTGGAC
GTCTCCGGCGTGCCCGCAGAGGTGCTGTGCAACATCGAGGCCGACACCTACTGGTGCATGAGCAAGCTGCTGGATGGCATTCAGGACAAC
TACACCTTTGCCCAACCTGGGATTCAAATGAAAGTGAAAATGTTAGAAGAACTCGTGAGCCGGATTGATGAGCAAGTGCACCGGCACCTG
GACCAACACGAAGTGAGATACCTGCAGTTTGCCTTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTGCCCCTGCGTTGTACCATCCGC
CTGTGGGACACCTACCAGTCTGAACCGGACGGCTTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTTCTCGTGAGATGGAGGAAGGAA
ATACTAGAAGAAAAAGATTTTCAAGAGCTGCTGCTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGATGATGAGGACATCAGCCTGTTG
CTGGCCGAGGCCTACCGCCTCAAGTTTGCTTTTGCCGACGCCCCCAATCACTACAAGAAATGAGCCCAGGCCCACCCGCAGCTGGCCTCA
CTGTCCCGGGTGGCGCGCCCCACCTGCCTGGCTGGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTAAAAGGCCTTGTGAGGTGGCCC
CACCCTCCAGGGGAGCTGGTGAAGATGGGCCACAGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCCTTTGTTTTCTGAGATACCAAA
GAGAGCCAGGGGAGGGCCCCGGGTTCGGCGGCCAGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGCAATGTCCTTGCCAAATGACTG
CCTCGTGCTGCCCCTAGTCCGGGGCAGCCTAGGAGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGCCAGGGCCGGAACGAGGTAGTG

>34605_34605_8_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000406902_TBC1D22A_chr22_47274549_ENST00000355704_length(amino acids)=401AA_BP=1
MNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIAL
LEKHFLQELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQP
KVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQ
MKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQE

--------------------------------------------------------------
>34605_34605_9_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000406902_TBC1D22A_chr22_47274549_ENST00000380995_length(transcript)=975nt_BP=496nt
CTCCAGGCTCCAGGGCAGCAGACACCACCCTCTCCGTGCCTGCTGGTGTTGGGCGGCTTGGAGGCTATGGTTCCTGGGTCCTCGTAGCAC
ATCCTGGTTCTGGGCCAGGACCTGAAGGAGCCACAGTGAAAGAGTGTTTCTGGATGTATCTGAGACAGACGGAGGGAACCCGAGCGTCAT
GTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGACTTCCTC
GATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGACAGCGAG
GAGCTGAGGGACCCTGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTGAATGAG
ATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAGCCAGTG
CGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAAGAATAT
TTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCTCGCATG
AGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCCAGTGGA
TACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAGCCTTTCCAGGTTGTGGTCGGCCTCAG

>34605_34605_9_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000406902_TBC1D22A_chr22_47274549_ENST00000380995_length(amino acids)=255AA_BP=1
MNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIAL
LEKHFLQELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQP

--------------------------------------------------------------
>34605_34605_10_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000406902_TBC1D22A_chr22_47274549_ENST00000407381_length(transcript)=1870nt_BP=496nt
CTCCAGGCTCCAGGGCAGCAGACACCACCCTCTCCGTGCCTGCTGGTGTTGGGCGGCTTGGAGGCTATGGTTCCTGGGTCCTCGTAGCAC
ATCCTGGTTCTGGGCCAGGACCTGAAGGAGCCACAGTGAAAGAGTGTTTCTGGATGTATCTGAGACAGACGGAGGGAACCCGAGCGTCAT
GTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGACTTCCTC
GATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGACAGCGAG
GAGCTGAGGGACCCTGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTGAATGAG
ATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAGCCAGTG
CGTCCAATGACGTGGAAGCTCCTCTCAGGTTACCTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAAGAATAT
TTTGCATTTATTGAGCACTATTACGATTCTAGGAACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCTCGCATG
AGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTGACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCCAGTGGA
TACGTTCAGGGTATAAATGATCTCGTCACTCCTTTCTTTGTGGTCTTCATTTGTGAATACATAGAGGCAGAGGAGGTGGACACGGTGGAC
GTCTCCGGCGTGCCCGCAGAGGTGCTGTGCAACATCGAGGCCGACACCTACTGGTGCATGAGCAAGCTGCTGGATGGCATTCAGGACAAC
TACACCTTTGCCCAACCTGGGATTCAAATGAAAGTGAAAATGTTAGAAGAACTCGTGAGCCGGATTGATGAGCAAGTGCACCGGCACCTG
GACCAACACGAAGTGAGATACCTGCAGTTTGCCTTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTGCCCCTGCGTTGTACCATCCGC
CTGTGGGACACCTACCAGTCTGAACCGGACGGCTTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTTCTCGTGAGATGGAGGAAGGAA
ATACTAGAAGAAAAAGATTTTCAAGAGCTGCTGCTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGATGATGAGGACATCAGCCTGTTG
CTGGCCGAGGCCTACCGCCTCAAGTTTGCTTTTGCCGACGCCCCCAATCACTACAAGAAATGAGCCCAGGCCCACCCGCAGCTGGCCTCA
CTGTCCCGGGTGGCGCGCCCCACCTGCCTGGCTGGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTAAAAGGCCTTGTGAGGTGGCCC
CACCCTCCAGGGGAGCTGGTGAAGATGGGCCACAGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCCTTTGTTTTCTGAGATACCAAA
GAGAGCCAGGGGAGGGCCCCGGGTTCGGCGGCCAGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGCAATGTCCTTGCCAAATGACTG
CCTCGTGCTGCCCCTAGTCCGGGGCAGCCTAGGAGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGCCAGGGCCGGAACGAGGTAGTG

>34605_34605_10_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000406902_TBC1D22A_chr22_47274549_ENST00000407381_length(amino acids)=401AA_BP=1
MNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIAL
LEKHFLQELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQP
KVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQ
MKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQE

--------------------------------------------------------------
>34605_34605_11_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000490378_TBC1D22A_chr22_47274549_ENST00000337137_length(transcript)=3177nt_BP=193nt
GAGATGACTTCCTCGATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGCTGGTCCAGGGACCC
TCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTGAATGAGATCAAAGGTCACCTGGAAATTGCCTTATTGG
AAAAACATTTCTTAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAGCCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTAC
CTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAAGAATATTTTGCATTTATTGAGCACTATTACGATTCTAGG
AACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCTCGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTG
ACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCCAGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCT
TTCTTTGTGGTCTTCATTTGTGAATACATAGAGGCAGAGGAGGTGGACACGGTGGACGTCTCCGGCGTGCCCGCAGAGGTGCTGTGCAAC
ATCGAGGCCGACACCTACTGGTGCATGAGCAAGCTGCTGGATGGCATTCAGGACAACTACACCTTTGCCCAACCTGGGATTCAAATGAAA
GTGAAAATGTTAGAAGAACTCGTGAGCCGGATTGATGAGCAAGTGCACCGGCACCTGGACCAACACGAAGTGAGATACCTGCAGTTTGCC
TTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTGCCCCTGCGTTGTACCATCCGCCTGTGGGACACCTACCAGTCTGAACCGGACGGC
TTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTTCTCGTGAGATGGAGGAAGGAAATACTAGAAGAAAAAGATTTTCAAGAGCTGCTG
CTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGATGATGAGGACATCAGCCTGTTGCTGGCCGAGGCCTACCGCCTCAAGTTTGCTTTT
GCCGACGCCCCCAATCACTACAAGAAATGAGCCCAGGCCCACCCGCAGCTGGCCTCACTGTCCCGGGTGGCGCGCCCCACCTGCCTGGCT
GGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTAAAAGGCCTTGTGAGGTGGCCCCACCCTCCAGGGGAGCTGGTGAAGATGGGCCAC
AGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCCTTTGTTTTCTGAGATACCAAAGAGAGCCAGGGGAGGGCCCCGGGTTCGGCGGCC
AGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGCAATGTCCTTGCCAAATGACTGCCTCGTGCTGCCCCTAGTCCGGGGCAGCCTAGG
AGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGCCAGGGCCGGAACGAGGTAGTGGCCATCTCATACCTACTCTGAAATGCAAAACTT
CTATTCTGTTGAGTGAAAGAATAAAATGTAGACAAAATCTAGACCGAGACGTTGCGCTGACCCGGGGTCTCTGTGCCGCGAGGTCCCCTC
ACAGCTGTATTTCACTGCTGCTGGCCCTTTCCCTCCGTGTGTTTTCCTGCTTGCTTGGTTTAAACGTGGCTGGGAAGCTGAAGGCTGGAG
TCCAAGCCGTGAGCCCGCCGAGTGCCTGGGAGGCCGTGGGACCAAAGGCTGGGAGCAGAGGGAGGCCTCGCCATCGCCTTACTTTCCACC
TTGAACCTCTTTTACAAGAGAGAAACCCCCACCTCCCTGAGGTCCAGGGCCAAGTGGCCCCGCCACGCAGGTAGGCGCCGGCCTCAGCCA
GAGCCCCTGGAGGCCCACCCAGGCTGTCGGGCCATGTTGGGCTGGCAGACGGGCAGGGGGTCGCGTCCCTGTCATCAAAGCCCTGAACCA
CAGTGCTCTTCTCACCGCAGCCTGGAAGCGGAATGAGCTTTTGGAGACTTCCTGGGACTTGCTGTCCTTGTCCAGGTCTGCCAGGTGTAG
GGGAGGTGTGACTGGTTCCATCATGGACCGGTTCCTCCATGGACCGGTTCCTCCGTGGACCGGTTCCGCCATGGACCGGTTCCGCCATGG
ACCACTCCTGCCCTGGACCACTCCTGCCCTGGACCGGTTCTGCCGTGGACTGGTTCCCGCCGTGGACCAGTTCCCGCTGTATACTGGTTC
TGCCCTGGACTGGTTCCCGCTGTGGACTGGTTCCTTGGGGCTCTAAGTGCGGAAGGGCCCAGAGCTGGTCCCTGCCCAGCGCCCTGCTAG
GGCTGTGTCCTTGGCTCCAGGGGCCTTGGGACTGGCTTCCCAGCGTTCCCTCGGTGTGTCACAGGCTGCATGACCCCTGGAATGCGGGCA
GGGCCACAGCCACAGTCTGTCTGATCCCTGAGCCCAGGACAGGCTCACGTCCTCAGCGACCCACTGGTGACTGACTTCCCAGACTCTCCT
CTGTCCCTCAGGAGCAGCCGTGTCCTCTCCCAGGCCCTAGGACACTGCCAGAGACTGTGGGACATACAGGCATAAGTGATGTGTGTGTTT
CTGCTTCTGTTTTAAAAATCCAGGGTCATTACACACAGCATGGAAATTAGCACAAAATGCTGTGCAAACGTCAGATGCTCCCAAACCAGC
AAAGGGATGGGCTTGCTTCACATCAGATGCGGGCACGCCTTACCCCTGCCTTCCGTGTCCCCACCCCAGGGTCAAGGGTTCCTCAGACCA
GCCATGCCTCCTCCTCCTGCCGCCTCCTTTTCTAGATGGGGAGGGGATTCCGTCACAAGAAGAGCCGCCCCTCGGCCGTGTGCAGGAAGC
CCCATGTCGCTTTGCCGAGATCAGCCCTGGGAGGATCCCCTTCTCCAGCTCAGATCATGCCGTGTGGCCAGAAGGCTGCGGACACAACTG
ACCTGCTTCTCGAGGTGGTTGATGTTTTAAACAGGAAGCTCCACGGAGTTCAGCCCTGTGTGCATTTCCTCATGTATGTAAACGCCAAGA
CTGAATGTGAGAGGTGTTGGCCGCGGGCCTTAAGTCTGAGCAGATCCATCTGGAATGTTCGGGGTGTGCTGTCTGGATGTGGTGCGCTAA

>34605_34605_11_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000490378_TBC1D22A_chr22_47274549_ENST00000337137_length(amino acids)=300AA_BP=
MSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILF
IWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVS
RIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLFLQNLPTA

--------------------------------------------------------------
>34605_34605_12_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000490378_TBC1D22A_chr22_47274549_ENST00000355704_length(transcript)=1570nt_BP=193nt
GAGATGACTTCCTCGATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGCTGGTCCAGGGACCC
TCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTGAATGAGATCAAAGGTCACCTGGAAATTGCCTTATTGG
AAAAACATTTCTTAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAGCCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTAC
CTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAAGAATATTTTGCATTTATTGAGCACTATTACGATTCTAGG
AACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCTCGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTG
ACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCCAGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCT
TTCTTTGTGGTCTTCATTTGTGAATACATAGAGGCAGAGGAGGTGGACACGGTGGACGTCTCCGGCGTGCCCGCAGAGGTGCTGTGCAAC
ATCGAGGCCGACACCTACTGGTGCATGAGCAAGCTGCTGGATGGCATTCAGGACAACTACACCTTTGCCCAACCTGGGATTCAAATGAAA
GTGAAAATGTTAGAAGAACTCGTGAGCCGGATTGATGAGCAAGTGCACCGGCACCTGGACCAACACGAAGTGAGATACCTGCAGTTTGCC
TTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTGCCCCTGCGTTGTACCATCCGCCTGTGGGACACCTACCAGTCTGAACCGGACGGC
TTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTTCTCGTGAGATGGAGGAAGGAAATACTAGAAGAAAAAGATTTTCAAGAGCTGCTG
CTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGATGATGAGGACATCAGCCTGTTGCTGGCCGAGGCCTACCGCCTCAAGTTTGCTTTT
GCCGACGCCCCCAATCACTACAAGAAATGAGCCCAGGCCCACCCGCAGCTGGCCTCACTGTCCCGGGTGGCGCGCCCCACCTGCCTGGCT
GGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTAAAAGGCCTTGTGAGGTGGCCCCACCCTCCAGGGGAGCTGGTGAAGATGGGCCAC
AGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCCTTTGTTTTCTGAGATACCAAAGAGAGCCAGGGGAGGGCCCCGGGTTCGGCGGCC
AGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGCAATGTCCTTGCCAAATGACTGCCTCGTGCTGCCCCTAGTCCGGGGCAGCCTAGG
AGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGCCAGGGCCGGAACGAGGTAGTGGCCATCTCATACCTACTCTGAAATGCAAAACTT

>34605_34605_12_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000490378_TBC1D22A_chr22_47274549_ENST00000355704_length(amino acids)=300AA_BP=
MSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILF
IWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVS
RIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLFLQNLPTA

--------------------------------------------------------------
>34605_34605_13_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000490378_TBC1D22A_chr22_47274549_ENST00000380995_length(transcript)=672nt_BP=193nt
GAGATGACTTCCTCGATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGCTGGTCCAGGGACCC
TCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTGAATGAGATCAAAGGTCACCTGGAAATTGCCTTATTGG
AAAAACATTTCTTAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAGCCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTAC
CTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAAGAATATTTTGCATTTATTGAGCACTATTACGATTCTAGG
AACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCTCGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTG
ACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCCAGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCT
TTCTTTGTGGTCTTCATTTGTGAATACATAGCCTTTCCAGGTTGTGGTCGGCCTCAGATTCCCATCCTTGCTGTGATCTGGAGAGATGAG

>34605_34605_13_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000490378_TBC1D22A_chr22_47274549_ENST00000380995_length(amino acids)=154AA_BP=
MSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILF

--------------------------------------------------------------
>34605_34605_14_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000490378_TBC1D22A_chr22_47274549_ENST00000407381_length(transcript)=1567nt_BP=193nt
GAGATGACTTCCTCGATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGCTGGTCCAGGGACCC
TCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTGAATGAGATCAAAGGTCACCTGGAAATTGCCTTATTGG
AAAAACATTTCTTAGGAATTACGGAGGTTGAGCTGGTCCGGAATCCCTAAGCCAGTGCGTCCAATGACGTGGAAGCTCCTCTCAGGTTAC
CTTCCCGCCAATGTAGACCGGAGACCAGCCACTCTCCAGAGAAAACAAAAAGAATATTTTGCATTTATTGAGCACTATTACGATTCTAGG
AACGACGAAGTTCACCAGGACACATACAGGCAGATCCACATAGACATCCCTCGCATGAGCCCTGAAGCGTTGATCCTGCAGCCCAAGGTG
ACGGAGATTTTTGAAAGGATCTTGTTCATATGGGCGATCCGCCACCCAGCCAGTGGATACGTTCAGGGTATAAATGATCTCGTCACTCCT
TTCTTTGTGGTCTTCATTTGTGAATACATAGAGGCAGAGGAGGTGGACACGGTGGACGTCTCCGGCGTGCCCGCAGAGGTGCTGTGCAAC
ATCGAGGCCGACACCTACTGGTGCATGAGCAAGCTGCTGGATGGCATTCAGGACAACTACACCTTTGCCCAACCTGGGATTCAAATGAAA
GTGAAAATGTTAGAAGAACTCGTGAGCCGGATTGATGAGCAAGTGCACCGGCACCTGGACCAACACGAAGTGAGATACCTGCAGTTTGCC
TTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTGCCCCTGCGTTGTACCATCCGCCTGTGGGACACCTACCAGTCTGAACCGGACGGC
TTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTTCTCGTGAGATGGAGGAAGGAAATACTAGAAGAAAAAGATTTTCAAGAGCTGCTG
CTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGATGATGAGGACATCAGCCTGTTGCTGGCCGAGGCCTACCGCCTCAAGTTTGCTTTT
GCCGACGCCCCCAATCACTACAAGAAATGAGCCCAGGCCCACCCGCAGCTGGCCTCACTGTCCCGGGTGGCGCGCCCCACCTGCCTGGCT
GGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTAAAAGGCCTTGTGAGGTGGCCCCACCCTCCAGGGGAGCTGGTGAAGATGGGCCAC
AGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCCTTTGTTTTCTGAGATACCAAAGAGAGCCAGGGGAGGGCCCCGGGTTCGGCGGCC
AGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGCAATGTCCTTGCCAAATGACTGCCTCGTGCTGCCCCTAGTCCGGGGCAGCCTAGG
AGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGCCAGGGCCGGAACGAGGTAGTGGCCATCTCATACCTACTCTGAAATGCAAAACTT

>34605_34605_14_GRAMD4-TBC1D22A_GRAMD4_chr22_47033857_ENST00000490378_TBC1D22A_chr22_47274549_ENST00000407381_length(amino acids)=300AA_BP=
MSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILF
IWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVS
RIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLFLQNLPTA

--------------------------------------------------------------
>34605_34605_15_GRAMD4-TBC1D22A_GRAMD4_chr22_47069711_ENST00000361034_TBC1D22A_chr22_47432966_ENST00000337137_length(transcript)=3843nt_BP=1423nt
CGTCATGTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGAC
TTCCTCGATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGAC
AGCGAGGAGCTGAGGGACCCTGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTG
AATGAGATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAGGAGCTCCGGAAGCTGCGAGAAGAAACCAACGCG
GAGATGCTGCGGCAGGAGCTGGACCGCGAGCGGCAGCGGCGGATGGAGCTGGAGCAGAAGGTGCAGGAGGTGCTGAAGGCCAGAACCGAG
GAGCAGATGGCTCAGCAGCCCCCAAAAGGGCAGGCCCAGGCCAGCAATGGAGCAGAGCGCCGGAGCCAGGGGCTGTCCTCGCGCCTGCAG
AAGTGGTTCTACGAGCGGTTTGGGGAGTACGTGGAGGACTTCCGGTTCCAGCCCGAGGAGAACACTGTGGAGACAGAGGAACCCCTGAGC
GCCCGCAGGTTAACTGAAAATATGAGACGGCTCAAGCGCGGTGCCAAGCCGGTCACTAACTTTGTGAAGAACCTCTCTGCCTTATCCGAC
TGGTACTCCGTCTACACGTCTGCCATTGCCTTCACCGTGTACATGAATGCCGTGTGGCATGGCTGGGCCATCCCATTGTTCTTATTTCTA
GCAATTCTGAGGTTATCCCTCAATTACCTCATCGCCAGGGGGTGGCGGATACAGTGGAGCATCGTGCCCGAAGTGTCTGAGCCCGTGGAA
CCTCCAAAGGAAGACCTGACTGTGTCTGAGAAGTTCCAGCTGGTGCTGGACGTCGCCCAGAAAGCCCAGAACCTTTTCGGGAAGATGGCT
GACATCCTGGAGAAGATCAAGAACTTGTTCATGTGGGTCCAGCCGGAGATCACACAGAAGCTGTATGTGGCGCTCTGGGCTGCCTTCCTG
GCCTCCTGCTTCTTCCCCTACCGCCTGGTGGGGCTTGCCGTGGGACTCTATGCTGGTATCAAGTTCTTCCTCATTGATTTCATCTTTAAA
CGCTGCCCGAGGCTGCGCGCCAAGTACGACACGCCCTATATCATCTGGAGGAGTCTCCCCACCGACCCGCAGCTCAAGGAGCGCTCCAGC
GCCGCAGTCTCACGCAGGCTGCAGACGACCTCGTCACGGAGCTACGTACCCAGCGCACCGGCCGGCCTGGGTAAAGAGGAGGACGCCGGT
CGCTTCCACAGCACCAAGAAGGGCAATTTCCACGAGATCTTCAATCTGACAGAAAACGAGCGTCCGCTGGCGGAGCAAGTGCACCGGCAC
CTGGACCAACACGAAGTGAGATACCTGCAGTTTGCCTTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTGCCCCTGCGTTGTACCATC
CGCCTGTGGGACACCTACCAGTCTGAACCGGACGGCTTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTTCTCGTGAGATGGAGGAAG
GAAATACTAGAAGAAAAAGATTTTCAAGAGCTGCTGCTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGATGATGAGGACATCAGCCTG
TTGCTGGCCGAGGCCTACCGCCTCAAGTTTGCTTTTGCCGACGCCCCCAATCACTACAAGAAATGAGCCCAGGCCCACCCGCAGCTGGCC
TCACTGTCCCGGGTGGCGCGCCCCACCTGCCTGGCTGGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTAAAAGGCCTTGTGAGGTGG
CCCCACCCTCCAGGGGAGCTGGTGAAGATGGGCCACAGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCCTTTGTTTTCTGAGATACC
AAAGAGAGCCAGGGGAGGGCCCCGGGTTCGGCGGCCAGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGCAATGTCCTTGCCAAATGA
CTGCCTCGTGCTGCCCCTAGTCCGGGGCAGCCTAGGAGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGCCAGGGCCGGAACGAGGTA
GTGGCCATCTCATACCTACTCTGAAATGCAAAACTTCTATTCTGTTGAGTGAAAGAATAAAATGTAGACAAAATCTAGACCGAGACGTTG
CGCTGACCCGGGGTCTCTGTGCCGCGAGGTCCCCTCACAGCTGTATTTCACTGCTGCTGGCCCTTTCCCTCCGTGTGTTTTCCTGCTTGC
TTGGTTTAAACGTGGCTGGGAAGCTGAAGGCTGGAGTCCAAGCCGTGAGCCCGCCGAGTGCCTGGGAGGCCGTGGGACCAAAGGCTGGGA
GCAGAGGGAGGCCTCGCCATCGCCTTACTTTCCACCTTGAACCTCTTTTACAAGAGAGAAACCCCCACCTCCCTGAGGTCCAGGGCCAAG
TGGCCCCGCCACGCAGGTAGGCGCCGGCCTCAGCCAGAGCCCCTGGAGGCCCACCCAGGCTGTCGGGCCATGTTGGGCTGGCAGACGGGC
AGGGGGTCGCGTCCCTGTCATCAAAGCCCTGAACCACAGTGCTCTTCTCACCGCAGCCTGGAAGCGGAATGAGCTTTTGGAGACTTCCTG
GGACTTGCTGTCCTTGTCCAGGTCTGCCAGGTGTAGGGGAGGTGTGACTGGTTCCATCATGGACCGGTTCCTCCATGGACCGGTTCCTCC
GTGGACCGGTTCCGCCATGGACCGGTTCCGCCATGGACCACTCCTGCCCTGGACCACTCCTGCCCTGGACCGGTTCTGCCGTGGACTGGT
TCCCGCCGTGGACCAGTTCCCGCTGTATACTGGTTCTGCCCTGGACTGGTTCCCGCTGTGGACTGGTTCCTTGGGGCTCTAAGTGCGGAA
GGGCCCAGAGCTGGTCCCTGCCCAGCGCCCTGCTAGGGCTGTGTCCTTGGCTCCAGGGGCCTTGGGACTGGCTTCCCAGCGTTCCCTCGG
TGTGTCACAGGCTGCATGACCCCTGGAATGCGGGCAGGGCCACAGCCACAGTCTGTCTGATCCCTGAGCCCAGGACAGGCTCACGTCCTC
AGCGACCCACTGGTGACTGACTTCCCAGACTCTCCTCTGTCCCTCAGGAGCAGCCGTGTCCTCTCCCAGGCCCTAGGACACTGCCAGAGA
CTGTGGGACATACAGGCATAAGTGATGTGTGTGTTTCTGCTTCTGTTTTAAAAATCCAGGGTCATTACACACAGCATGGAAATTAGCACA
AAATGCTGTGCAAACGTCAGATGCTCCCAAACCAGCAAAGGGATGGGCTTGCTTCACATCAGATGCGGGCACGCCTTACCCCTGCCTTCC
GTGTCCCCACCCCAGGGTCAAGGGTTCCTCAGACCAGCCATGCCTCCTCCTCCTGCCGCCTCCTTTTCTAGATGGGGAGGGGATTCCGTC
ACAAGAAGAGCCGCCCCTCGGCCGTGTGCAGGAAGCCCCATGTCGCTTTGCCGAGATCAGCCCTGGGAGGATCCCCTTCTCCAGCTCAGA
TCATGCCGTGTGGCCAGAAGGCTGCGGACACAACTGACCTGCTTCTCGAGGTGGTTGATGTTTTAAACAGGAAGCTCCACGGAGTTCAGC
CCTGTGTGCATTTCCTCATGTATGTAAACGCCAAGACTGAATGTGAGAGGTGTTGGCCGCGGGCCTTAAGTCTGAGCAGATCCATCTGGA

>34605_34605_15_GRAMD4-TBC1D22A_GRAMD4_chr22_47069711_ENST00000361034_TBC1D22A_chr22_47432966_ENST00000337137_length(amino acids)=580AA_BP=1
MNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIAL
LEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYV
EDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTVYMNAVWHGWAIPLFLFLAILRLSLNYLI
ARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVG
LAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSRSYVPSAPAGLGKEEDAGRFHSTKKGNFH
EIFNLTENERPLAEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQEL

--------------------------------------------------------------
>34605_34605_16_GRAMD4-TBC1D22A_GRAMD4_chr22_47069711_ENST00000361034_TBC1D22A_chr22_47432967_ENST00000337137_length(transcript)=3843nt_BP=1423nt
CGTCATGTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGAC
TTCCTCGATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGAC
AGCGAGGAGCTGAGGGACCCTGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTG
AATGAGATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAGGAGCTCCGGAAGCTGCGAGAAGAAACCAACGCG
GAGATGCTGCGGCAGGAGCTGGACCGCGAGCGGCAGCGGCGGATGGAGCTGGAGCAGAAGGTGCAGGAGGTGCTGAAGGCCAGAACCGAG
GAGCAGATGGCTCAGCAGCCCCCAAAAGGGCAGGCCCAGGCCAGCAATGGAGCAGAGCGCCGGAGCCAGGGGCTGTCCTCGCGCCTGCAG
AAGTGGTTCTACGAGCGGTTTGGGGAGTACGTGGAGGACTTCCGGTTCCAGCCCGAGGAGAACACTGTGGAGACAGAGGAACCCCTGAGC
GCCCGCAGGTTAACTGAAAATATGAGACGGCTCAAGCGCGGTGCCAAGCCGGTCACTAACTTTGTGAAGAACCTCTCTGCCTTATCCGAC
TGGTACTCCGTCTACACGTCTGCCATTGCCTTCACCGTGTACATGAATGCCGTGTGGCATGGCTGGGCCATCCCATTGTTCTTATTTCTA
GCAATTCTGAGGTTATCCCTCAATTACCTCATCGCCAGGGGGTGGCGGATACAGTGGAGCATCGTGCCCGAAGTGTCTGAGCCCGTGGAA
CCTCCAAAGGAAGACCTGACTGTGTCTGAGAAGTTCCAGCTGGTGCTGGACGTCGCCCAGAAAGCCCAGAACCTTTTCGGGAAGATGGCT
GACATCCTGGAGAAGATCAAGAACTTGTTCATGTGGGTCCAGCCGGAGATCACACAGAAGCTGTATGTGGCGCTCTGGGCTGCCTTCCTG
GCCTCCTGCTTCTTCCCCTACCGCCTGGTGGGGCTTGCCGTGGGACTCTATGCTGGTATCAAGTTCTTCCTCATTGATTTCATCTTTAAA
CGCTGCCCGAGGCTGCGCGCCAAGTACGACACGCCCTATATCATCTGGAGGAGTCTCCCCACCGACCCGCAGCTCAAGGAGCGCTCCAGC
GCCGCAGTCTCACGCAGGCTGCAGACGACCTCGTCACGGAGCTACGTACCCAGCGCACCGGCCGGCCTGGGTAAAGAGGAGGACGCCGGT
CGCTTCCACAGCACCAAGAAGGGCAATTTCCACGAGATCTTCAATCTGACAGAAAACGAGCGTCCGCTGGCGGAGCAAGTGCACCGGCAC
CTGGACCAACACGAAGTGAGATACCTGCAGTTTGCCTTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTGCCCCTGCGTTGTACCATC
CGCCTGTGGGACACCTACCAGTCTGAACCGGACGGCTTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTTCTCGTGAGATGGAGGAAG
GAAATACTAGAAGAAAAAGATTTTCAAGAGCTGCTGCTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGATGATGAGGACATCAGCCTG
TTGCTGGCCGAGGCCTACCGCCTCAAGTTTGCTTTTGCCGACGCCCCCAATCACTACAAGAAATGAGCCCAGGCCCACCCGCAGCTGGCC
TCACTGTCCCGGGTGGCGCGCCCCACCTGCCTGGCTGGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTAAAAGGCCTTGTGAGGTGG
CCCCACCCTCCAGGGGAGCTGGTGAAGATGGGCCACAGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCCTTTGTTTTCTGAGATACC
AAAGAGAGCCAGGGGAGGGCCCCGGGTTCGGCGGCCAGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGCAATGTCCTTGCCAAATGA
CTGCCTCGTGCTGCCCCTAGTCCGGGGCAGCCTAGGAGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGCCAGGGCCGGAACGAGGTA
GTGGCCATCTCATACCTACTCTGAAATGCAAAACTTCTATTCTGTTGAGTGAAAGAATAAAATGTAGACAAAATCTAGACCGAGACGTTG
CGCTGACCCGGGGTCTCTGTGCCGCGAGGTCCCCTCACAGCTGTATTTCACTGCTGCTGGCCCTTTCCCTCCGTGTGTTTTCCTGCTTGC
TTGGTTTAAACGTGGCTGGGAAGCTGAAGGCTGGAGTCCAAGCCGTGAGCCCGCCGAGTGCCTGGGAGGCCGTGGGACCAAAGGCTGGGA
GCAGAGGGAGGCCTCGCCATCGCCTTACTTTCCACCTTGAACCTCTTTTACAAGAGAGAAACCCCCACCTCCCTGAGGTCCAGGGCCAAG
TGGCCCCGCCACGCAGGTAGGCGCCGGCCTCAGCCAGAGCCCCTGGAGGCCCACCCAGGCTGTCGGGCCATGTTGGGCTGGCAGACGGGC
AGGGGGTCGCGTCCCTGTCATCAAAGCCCTGAACCACAGTGCTCTTCTCACCGCAGCCTGGAAGCGGAATGAGCTTTTGGAGACTTCCTG
GGACTTGCTGTCCTTGTCCAGGTCTGCCAGGTGTAGGGGAGGTGTGACTGGTTCCATCATGGACCGGTTCCTCCATGGACCGGTTCCTCC
GTGGACCGGTTCCGCCATGGACCGGTTCCGCCATGGACCACTCCTGCCCTGGACCACTCCTGCCCTGGACCGGTTCTGCCGTGGACTGGT
TCCCGCCGTGGACCAGTTCCCGCTGTATACTGGTTCTGCCCTGGACTGGTTCCCGCTGTGGACTGGTTCCTTGGGGCTCTAAGTGCGGAA
GGGCCCAGAGCTGGTCCCTGCCCAGCGCCCTGCTAGGGCTGTGTCCTTGGCTCCAGGGGCCTTGGGACTGGCTTCCCAGCGTTCCCTCGG
TGTGTCACAGGCTGCATGACCCCTGGAATGCGGGCAGGGCCACAGCCACAGTCTGTCTGATCCCTGAGCCCAGGACAGGCTCACGTCCTC
AGCGACCCACTGGTGACTGACTTCCCAGACTCTCCTCTGTCCCTCAGGAGCAGCCGTGTCCTCTCCCAGGCCCTAGGACACTGCCAGAGA
CTGTGGGACATACAGGCATAAGTGATGTGTGTGTTTCTGCTTCTGTTTTAAAAATCCAGGGTCATTACACACAGCATGGAAATTAGCACA
AAATGCTGTGCAAACGTCAGATGCTCCCAAACCAGCAAAGGGATGGGCTTGCTTCACATCAGATGCGGGCACGCCTTACCCCTGCCTTCC
GTGTCCCCACCCCAGGGTCAAGGGTTCCTCAGACCAGCCATGCCTCCTCCTCCTGCCGCCTCCTTTTCTAGATGGGGAGGGGATTCCGTC
ACAAGAAGAGCCGCCCCTCGGCCGTGTGCAGGAAGCCCCATGTCGCTTTGCCGAGATCAGCCCTGGGAGGATCCCCTTCTCCAGCTCAGA
TCATGCCGTGTGGCCAGAAGGCTGCGGACACAACTGACCTGCTTCTCGAGGTGGTTGATGTTTTAAACAGGAAGCTCCACGGAGTTCAGC
CCTGTGTGCATTTCCTCATGTATGTAAACGCCAAGACTGAATGTGAGAGGTGTTGGCCGCGGGCCTTAAGTCTGAGCAGATCCATCTGGA

>34605_34605_16_GRAMD4-TBC1D22A_GRAMD4_chr22_47069711_ENST00000361034_TBC1D22A_chr22_47432967_ENST00000337137_length(amino acids)=580AA_BP=1
MNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIAL
LEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYV
EDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTVYMNAVWHGWAIPLFLFLAILRLSLNYLI
ARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVG
LAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSRSYVPSAPAGLGKEEDAGRFHSTKKGNFH
EIFNLTENERPLAEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQEL

--------------------------------------------------------------
>34605_34605_17_GRAMD4-TBC1D22A_GRAMD4_chr22_47069711_ENST00000406902_TBC1D22A_chr22_47432966_ENST00000337137_length(transcript)=4017nt_BP=1597nt
CTCCAGGCTCCAGGGCAGCAGACACCACCCTCTCCGTGCCTGCTGGTGTTGGGCGGCTTGGAGGCTATGGTTCCTGGGTCCTCGTAGCAC
ATCCTGGTTCTGGGCCAGGACCTGAAGGAGCCACAGTGAAAGAGTGTTTCTGGATGTATCTGAGACAGACGGAGGGAACCCGAGCGTCAT
GTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGACTTCCTC
GATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGACAGCGAG
GAGCTGAGGGACCCTGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTGAATGAG
ATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAGGAGCTCCGGAAGCTGCGAGAAGAAACCAACGCGGAGATG
CTGCGGCAGGAGCTGGACCGCGAGCGGCAGCGGCGGATGGAGCTGGAGCAGAAGGTGCAGGAGGTGCTGAAGGCCAGAACCGAGGAGCAG
ATGGCTCAGCAGCCCCCAAAAGGGCAGGCCCAGGCCAGCAATGGAGCAGAGCGCCGGAGCCAGGGGCTGTCCTCGCGCCTGCAGAAGTGG
TTCTACGAGCGGTTTGGGGAGTACGTGGAGGACTTCCGGTTCCAGCCCGAGGAGAACACTGTGGAGACAGAGGAACCCCTGAGCGCCCGC
AGGTTAACTGAAAATATGAGACGGCTCAAGCGCGGTGCCAAGCCGGTCACTAACTTTGTGAAGAACCTCTCTGCCTTATCCGACTGGTAC
TCCGTCTACACGTCTGCCATTGCCTTCACCGTGTACATGAATGCCGTGTGGCATGGCTGGGCCATCCCATTGTTCTTATTTCTAGCAATT
CTGAGGTTATCCCTCAATTACCTCATCGCCAGGGGGTGGCGGATACAGTGGAGCATCGTGCCCGAAGTGTCTGAGCCCGTGGAACCTCCA
AAGGAAGACCTGACTGTGTCTGAGAAGTTCCAGCTGGTGCTGGACGTCGCCCAGAAAGCCCAGAACCTTTTCGGGAAGATGGCTGACATC
CTGGAGAAGATCAAGAACTTGTTCATGTGGGTCCAGCCGGAGATCACACAGAAGCTGTATGTGGCGCTCTGGGCTGCCTTCCTGGCCTCC
TGCTTCTTCCCCTACCGCCTGGTGGGGCTTGCCGTGGGACTCTATGCTGGTATCAAGTTCTTCCTCATTGATTTCATCTTTAAACGCTGC
CCGAGGCTGCGCGCCAAGTACGACACGCCCTATATCATCTGGAGGAGTCTCCCCACCGACCCGCAGCTCAAGGAGCGCTCCAGCGCCGCA
GTCTCACGCAGGCTGCAGACGACCTCGTCACGGAGCTACGTACCCAGCGCACCGGCCGGCCTGGGTAAAGAGGAGGACGCCGGTCGCTTC
CACAGCACCAAGAAGGGCAATTTCCACGAGATCTTCAATCTGACAGAAAACGAGCGTCCGCTGGCGGAGCAAGTGCACCGGCACCTGGAC
CAACACGAAGTGAGATACCTGCAGTTTGCCTTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTGCCCCTGCGTTGTACCATCCGCCTG
TGGGACACCTACCAGTCTGAACCGGACGGCTTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTTCTCGTGAGATGGAGGAAGGAAATA
CTAGAAGAAAAAGATTTTCAAGAGCTGCTGCTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGATGATGAGGACATCAGCCTGTTGCTG
GCCGAGGCCTACCGCCTCAAGTTTGCTTTTGCCGACGCCCCCAATCACTACAAGAAATGAGCCCAGGCCCACCCGCAGCTGGCCTCACTG
TCCCGGGTGGCGCGCCCCACCTGCCTGGCTGGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTAAAAGGCCTTGTGAGGTGGCCCCAC
CCTCCAGGGGAGCTGGTGAAGATGGGCCACAGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCCTTTGTTTTCTGAGATACCAAAGAG
AGCCAGGGGAGGGCCCCGGGTTCGGCGGCCAGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGCAATGTCCTTGCCAAATGACTGCCT
CGTGCTGCCCCTAGTCCGGGGCAGCCTAGGAGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGCCAGGGCCGGAACGAGGTAGTGGCC
ATCTCATACCTACTCTGAAATGCAAAACTTCTATTCTGTTGAGTGAAAGAATAAAATGTAGACAAAATCTAGACCGAGACGTTGCGCTGA
CCCGGGGTCTCTGTGCCGCGAGGTCCCCTCACAGCTGTATTTCACTGCTGCTGGCCCTTTCCCTCCGTGTGTTTTCCTGCTTGCTTGGTT
TAAACGTGGCTGGGAAGCTGAAGGCTGGAGTCCAAGCCGTGAGCCCGCCGAGTGCCTGGGAGGCCGTGGGACCAAAGGCTGGGAGCAGAG
GGAGGCCTCGCCATCGCCTTACTTTCCACCTTGAACCTCTTTTACAAGAGAGAAACCCCCACCTCCCTGAGGTCCAGGGCCAAGTGGCCC
CGCCACGCAGGTAGGCGCCGGCCTCAGCCAGAGCCCCTGGAGGCCCACCCAGGCTGTCGGGCCATGTTGGGCTGGCAGACGGGCAGGGGG
TCGCGTCCCTGTCATCAAAGCCCTGAACCACAGTGCTCTTCTCACCGCAGCCTGGAAGCGGAATGAGCTTTTGGAGACTTCCTGGGACTT
GCTGTCCTTGTCCAGGTCTGCCAGGTGTAGGGGAGGTGTGACTGGTTCCATCATGGACCGGTTCCTCCATGGACCGGTTCCTCCGTGGAC
CGGTTCCGCCATGGACCGGTTCCGCCATGGACCACTCCTGCCCTGGACCACTCCTGCCCTGGACCGGTTCTGCCGTGGACTGGTTCCCGC
CGTGGACCAGTTCCCGCTGTATACTGGTTCTGCCCTGGACTGGTTCCCGCTGTGGACTGGTTCCTTGGGGCTCTAAGTGCGGAAGGGCCC
AGAGCTGGTCCCTGCCCAGCGCCCTGCTAGGGCTGTGTCCTTGGCTCCAGGGGCCTTGGGACTGGCTTCCCAGCGTTCCCTCGGTGTGTC
ACAGGCTGCATGACCCCTGGAATGCGGGCAGGGCCACAGCCACAGTCTGTCTGATCCCTGAGCCCAGGACAGGCTCACGTCCTCAGCGAC
CCACTGGTGACTGACTTCCCAGACTCTCCTCTGTCCCTCAGGAGCAGCCGTGTCCTCTCCCAGGCCCTAGGACACTGCCAGAGACTGTGG
GACATACAGGCATAAGTGATGTGTGTGTTTCTGCTTCTGTTTTAAAAATCCAGGGTCATTACACACAGCATGGAAATTAGCACAAAATGC
TGTGCAAACGTCAGATGCTCCCAAACCAGCAAAGGGATGGGCTTGCTTCACATCAGATGCGGGCACGCCTTACCCCTGCCTTCCGTGTCC
CCACCCCAGGGTCAAGGGTTCCTCAGACCAGCCATGCCTCCTCCTCCTGCCGCCTCCTTTTCTAGATGGGGAGGGGATTCCGTCACAAGA
AGAGCCGCCCCTCGGCCGTGTGCAGGAAGCCCCATGTCGCTTTGCCGAGATCAGCCCTGGGAGGATCCCCTTCTCCAGCTCAGATCATGC
CGTGTGGCCAGAAGGCTGCGGACACAACTGACCTGCTTCTCGAGGTGGTTGATGTTTTAAACAGGAAGCTCCACGGAGTTCAGCCCTGTG
TGCATTTCCTCATGTATGTAAACGCCAAGACTGAATGTGAGAGGTGTTGGCCGCGGGCCTTAAGTCTGAGCAGATCCATCTGGAATGTTC

>34605_34605_17_GRAMD4-TBC1D22A_GRAMD4_chr22_47069711_ENST00000406902_TBC1D22A_chr22_47432966_ENST00000337137_length(amino acids)=580AA_BP=1
MNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIAL
LEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYV
EDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTVYMNAVWHGWAIPLFLFLAILRLSLNYLI
ARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVG
LAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSRSYVPSAPAGLGKEEDAGRFHSTKKGNFH
EIFNLTENERPLAEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQEL

--------------------------------------------------------------
>34605_34605_18_GRAMD4-TBC1D22A_GRAMD4_chr22_47069711_ENST00000406902_TBC1D22A_chr22_47432967_ENST00000337137_length(transcript)=4017nt_BP=1597nt
CTCCAGGCTCCAGGGCAGCAGACACCACCCTCTCCGTGCCTGCTGGTGTTGGGCGGCTTGGAGGCTATGGTTCCTGGGTCCTCGTAGCAC
ATCCTGGTTCTGGGCCAGGACCTGAAGGAGCCACAGTGAAAGAGTGTTTCTGGATGTATCTGAGACAGACGGAGGGAACCCGAGCGTCAT
GTTAGGGTGAAGCAGAGGACCTCAGTGCTGAACATGCTAAGGAGGTTGGACAAAATCAGGTTCAGAGGTCACAAGAGAGATGACTTCCTC
GATCTAGCGGAGTCTCCAAATGCCTCGGACACCGAATGCAGCGACGAAATCCCCCTGAAGGTACCGCGGACCTCGCCCCGGGACAGCGAG
GAGCTGAGGGACCCTGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTGAATGAG
ATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAGGAGCTCCGGAAGCTGCGAGAAGAAACCAACGCGGAGATG
CTGCGGCAGGAGCTGGACCGCGAGCGGCAGCGGCGGATGGAGCTGGAGCAGAAGGTGCAGGAGGTGCTGAAGGCCAGAACCGAGGAGCAG
ATGGCTCAGCAGCCCCCAAAAGGGCAGGCCCAGGCCAGCAATGGAGCAGAGCGCCGGAGCCAGGGGCTGTCCTCGCGCCTGCAGAAGTGG
TTCTACGAGCGGTTTGGGGAGTACGTGGAGGACTTCCGGTTCCAGCCCGAGGAGAACACTGTGGAGACAGAGGAACCCCTGAGCGCCCGC
AGGTTAACTGAAAATATGAGACGGCTCAAGCGCGGTGCCAAGCCGGTCACTAACTTTGTGAAGAACCTCTCTGCCTTATCCGACTGGTAC
TCCGTCTACACGTCTGCCATTGCCTTCACCGTGTACATGAATGCCGTGTGGCATGGCTGGGCCATCCCATTGTTCTTATTTCTAGCAATT
CTGAGGTTATCCCTCAATTACCTCATCGCCAGGGGGTGGCGGATACAGTGGAGCATCGTGCCCGAAGTGTCTGAGCCCGTGGAACCTCCA
AAGGAAGACCTGACTGTGTCTGAGAAGTTCCAGCTGGTGCTGGACGTCGCCCAGAAAGCCCAGAACCTTTTCGGGAAGATGGCTGACATC
CTGGAGAAGATCAAGAACTTGTTCATGTGGGTCCAGCCGGAGATCACACAGAAGCTGTATGTGGCGCTCTGGGCTGCCTTCCTGGCCTCC
TGCTTCTTCCCCTACCGCCTGGTGGGGCTTGCCGTGGGACTCTATGCTGGTATCAAGTTCTTCCTCATTGATTTCATCTTTAAACGCTGC
CCGAGGCTGCGCGCCAAGTACGACACGCCCTATATCATCTGGAGGAGTCTCCCCACCGACCCGCAGCTCAAGGAGCGCTCCAGCGCCGCA
GTCTCACGCAGGCTGCAGACGACCTCGTCACGGAGCTACGTACCCAGCGCACCGGCCGGCCTGGGTAAAGAGGAGGACGCCGGTCGCTTC
CACAGCACCAAGAAGGGCAATTTCCACGAGATCTTCAATCTGACAGAAAACGAGCGTCCGCTGGCGGAGCAAGTGCACCGGCACCTGGAC
CAACACGAAGTGAGATACCTGCAGTTTGCCTTCCGCTGGATGAACAACCTGCTGATGAGGGAGGTGCCCCTGCGTTGTACCATCCGCCTG
TGGGACACCTACCAGTCTGAACCGGACGGCTTTTCTCATTTCCACTTGTACGTGTGCGCTGCTTTTCTCGTGAGATGGAGGAAGGAAATA
CTAGAAGAAAAAGATTTTCAAGAGCTGCTGCTCTTCCTCCAGAACCTGCCCACAGCCCACTGGGATGATGAGGACATCAGCCTGTTGCTG
GCCGAGGCCTACCGCCTCAAGTTTGCTTTTGCCGACGCCCCCAATCACTACAAGAAATGAGCCCAGGCCCACCCGCAGCTGGCCTCACTG
TCCCGGGTGGCGCGCCCCACCTGCCTGGCTGGTGGTAGGCCCCTGTGAGCTGGTCCCGGGCTGCTAAAAGGCCTTGTGAGGTGGCCCCAC
CCTCCAGGGGAGCTGGTGAAGATGGGCCACAGACCTGGTCTAGGGCTGACAAAGACAGGGACAGCCTTTGTTTTCTGAGATACCAAAGAG
AGCCAGGGGAGGGCCCCGGGTTCGGCGGCCAGAGGCAGGTCAGGGGTCCCCTCTCCCTCTCCCTGCAATGTCCTTGCCAAATGACTGCCT
CGTGCTGCCCCTAGTCCGGGGCAGCCTAGGAGGCCGACCCTCTTTGGAGTCCTGCTGTCTGGGTGCCAGGGCCGGAACGAGGTAGTGGCC
ATCTCATACCTACTCTGAAATGCAAAACTTCTATTCTGTTGAGTGAAAGAATAAAATGTAGACAAAATCTAGACCGAGACGTTGCGCTGA
CCCGGGGTCTCTGTGCCGCGAGGTCCCCTCACAGCTGTATTTCACTGCTGCTGGCCCTTTCCCTCCGTGTGTTTTCCTGCTTGCTTGGTT
TAAACGTGGCTGGGAAGCTGAAGGCTGGAGTCCAAGCCGTGAGCCCGCCGAGTGCCTGGGAGGCCGTGGGACCAAAGGCTGGGAGCAGAG
GGAGGCCTCGCCATCGCCTTACTTTCCACCTTGAACCTCTTTTACAAGAGAGAAACCCCCACCTCCCTGAGGTCCAGGGCCAAGTGGCCC
CGCCACGCAGGTAGGCGCCGGCCTCAGCCAGAGCCCCTGGAGGCCCACCCAGGCTGTCGGGCCATGTTGGGCTGGCAGACGGGCAGGGGG
TCGCGTCCCTGTCATCAAAGCCCTGAACCACAGTGCTCTTCTCACCGCAGCCTGGAAGCGGAATGAGCTTTTGGAGACTTCCTGGGACTT
GCTGTCCTTGTCCAGGTCTGCCAGGTGTAGGGGAGGTGTGACTGGTTCCATCATGGACCGGTTCCTCCATGGACCGGTTCCTCCGTGGAC
CGGTTCCGCCATGGACCGGTTCCGCCATGGACCACTCCTGCCCTGGACCACTCCTGCCCTGGACCGGTTCTGCCGTGGACTGGTTCCCGC
CGTGGACCAGTTCCCGCTGTATACTGGTTCTGCCCTGGACTGGTTCCCGCTGTGGACTGGTTCCTTGGGGCTCTAAGTGCGGAAGGGCCC
AGAGCTGGTCCCTGCCCAGCGCCCTGCTAGGGCTGTGTCCTTGGCTCCAGGGGCCTTGGGACTGGCTTCCCAGCGTTCCCTCGGTGTGTC
ACAGGCTGCATGACCCCTGGAATGCGGGCAGGGCCACAGCCACAGTCTGTCTGATCCCTGAGCCCAGGACAGGCTCACGTCCTCAGCGAC
CCACTGGTGACTGACTTCCCAGACTCTCCTCTGTCCCTCAGGAGCAGCCGTGTCCTCTCCCAGGCCCTAGGACACTGCCAGAGACTGTGG
GACATACAGGCATAAGTGATGTGTGTGTTTCTGCTTCTGTTTTAAAAATCCAGGGTCATTACACACAGCATGGAAATTAGCACAAAATGC
TGTGCAAACGTCAGATGCTCCCAAACCAGCAAAGGGATGGGCTTGCTTCACATCAGATGCGGGCACGCCTTACCCCTGCCTTCCGTGTCC
CCACCCCAGGGTCAAGGGTTCCTCAGACCAGCCATGCCTCCTCCTCCTGCCGCCTCCTTTTCTAGATGGGGAGGGGATTCCGTCACAAGA
AGAGCCGCCCCTCGGCCGTGTGCAGGAAGCCCCATGTCGCTTTGCCGAGATCAGCCCTGGGAGGATCCCCTTCTCCAGCTCAGATCATGC
CGTGTGGCCAGAAGGCTGCGGACACAACTGACCTGCTTCTCGAGGTGGTTGATGTTTTAAACAGGAAGCTCCACGGAGTTCAGCCCTGTG
TGCATTTCCTCATGTATGTAAACGCCAAGACTGAATGTGAGAGGTGTTGGCCGCGGGCCTTAAGTCTGAGCAGATCCATCTGGAATGTTC

>34605_34605_18_GRAMD4-TBC1D22A_GRAMD4_chr22_47069711_ENST00000406902_TBC1D22A_chr22_47432967_ENST00000337137_length(amino acids)=580AA_BP=1
MNMLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIAL
LEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYV
EDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTVYMNAVWHGWAIPLFLFLAILRLSLNYLI
ARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVG
LAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSRSYVPSAPAGLGKEEDAGRFHSTKKGNFH
EIFNLTENERPLAEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQEL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for GRAMD4-TBC1D22A

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for GRAMD4-TBC1D22A

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for GRAMD4-TBC1D22A

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source