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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GRAP2-ADSL (FusionGDB2 ID:34610)

Fusion Gene Summary for GRAP2-ADSL

check button Fusion gene summary
Fusion gene informationFusion gene name: GRAP2-ADSL
Fusion gene ID: 34610
HgeneTgene
Gene symbol

GRAP2

ADSL

Gene ID

9402

158

Gene nameGRB2 related adaptor protein 2adenylosuccinate lyase
SynonymsGADS|GRAP-2|GRB2L|GRBLG|GRID|GRPL|GrbX|Grf40|Mona|P38AMPS|ASASE|ASL
Cytomap

22q13.1

22q13.1

Type of geneprotein-codingprotein-coding
DescriptionGRB2-related adapter protein 2GRB-2-like proteinGRB2-related protein with insert domainSH3-SH2-SH3 adapter MonaSH3-SH2-SH3 adaptor moleculeadapter protein GRIDgrf-40grf40 adapter proteingrowth factor receptor-binding proteingrowth factor receptoradenylosuccinate lyaseadenylosuccinase
Modification date2020032720200315
UniProtAcc

O75791

P30566

Ensembl transtripts involved in fusion geneENST00000478445, ENST00000344138, 
ENST00000407075, ENST00000540310, 
ENST00000543252, ENST00000544756, 
ENST00000399090, 		ENST00000216194, 
ENST00000342312, ENST00000454266, 
ENST00000480775, 
Fusion gene scores* DoF score4 X 4 X 3=485 X 8 X 5=200
# samples 47
** MAII scorelog2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/200*10)=-1.51457317282976
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GRAP2 [Title/Abstract] AND ADSL [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGRAP2(40362040)-ADSL(40745836), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneADSL

GO:0006167

AMP biosynthetic process

11428554


check buttonFusion gene breakpoints across GRAP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ADSL (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-Z2-A8RT-06AGRAP2chr22

40362040

+ADSLchr22

40745836

+


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Fusion Gene ORF analysis for GRAP2-ADSL

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000478445ENST00000216194GRAP2chr22

40362040

+ADSLchr22

40745836

+
3UTR-3CDSENST00000478445ENST00000342312GRAP2chr22

40362040

+ADSLchr22

40745836

+
3UTR-3CDSENST00000478445ENST00000454266GRAP2chr22

40362040

+ADSLchr22

40745836

+
3UTR-intronENST00000478445ENST00000480775GRAP2chr22

40362040

+ADSLchr22

40745836

+
5CDS-intronENST00000344138ENST00000480775GRAP2chr22

40362040

+ADSLchr22

40745836

+
5CDS-intronENST00000407075ENST00000480775GRAP2chr22

40362040

+ADSLchr22

40745836

+
5CDS-intronENST00000540310ENST00000480775GRAP2chr22

40362040

+ADSLchr22

40745836

+
5CDS-intronENST00000543252ENST00000480775GRAP2chr22

40362040

+ADSLchr22

40745836

+
5CDS-intronENST00000544756ENST00000480775GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000344138ENST00000216194GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000344138ENST00000342312GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000344138ENST00000454266GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000407075ENST00000216194GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000407075ENST00000342312GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000407075ENST00000454266GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000540310ENST00000216194GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000540310ENST00000342312GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000540310ENST00000454266GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000543252ENST00000216194GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000543252ENST00000342312GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000543252ENST00000454266GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000544756ENST00000216194GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000544756ENST00000342312GRAP2chr22

40362040

+ADSLchr22

40745836

+
In-frameENST00000544756ENST00000454266GRAP2chr22

40362040

+ADSLchr22

40745836

+
intron-3CDSENST00000399090ENST00000216194GRAP2chr22

40362040

+ADSLchr22

40745836

+
intron-3CDSENST00000399090ENST00000342312GRAP2chr22

40362040

+ADSLchr22

40745836

+
intron-3CDSENST00000399090ENST00000454266GRAP2chr22

40362040

+ADSLchr22

40745836

+
intron-intronENST00000399090ENST00000480775GRAP2chr22

40362040

+ADSLchr22

40745836

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000543252GRAP2chr2240362040+ENST00000216194ADSLchr2240745836+23395554441856470
ENST00000543252GRAP2chr2240362040+ENST00000454266ADSLchr2240745836+19915554441898484
ENST00000543252GRAP2chr2240362040+ENST00000342312ADSLchr2240745836+21545554441679411
ENST00000344138GRAP2chr2240362040+ENST00000216194ADSLchr2240745836+24596754921976494
ENST00000344138GRAP2chr2240362040+ENST00000454266ADSLchr2240745836+21116754922018508
ENST00000344138GRAP2chr2240362040+ENST00000342312ADSLchr2240745836+22746754921799435
ENST00000540310GRAP2chr2240362040+ENST00000216194ADSLchr2240745836+21283441341645503
ENST00000540310GRAP2chr2240362040+ENST00000454266ADSLchr2240745836+17803441341687517
ENST00000540310GRAP2chr2240362040+ENST00000342312ADSLchr2240745836+19433441341468444
ENST00000544756GRAP2chr2240362040+ENST00000216194ADSLchr2240745836+23665823991883494
ENST00000544756GRAP2chr2240362040+ENST00000454266ADSLchr2240745836+20185823991925508
ENST00000544756GRAP2chr2240362040+ENST00000342312ADSLchr2240745836+21815823991706435
ENST00000407075GRAP2chr2240362040+ENST00000216194ADSLchr2240745836+24867025192003494
ENST00000407075GRAP2chr2240362040+ENST00000454266ADSLchr2240745836+21387025192045508
ENST00000407075GRAP2chr2240362040+ENST00000342312ADSLchr2240745836+23017025191826435

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000543252ENST00000216194GRAP2chr2240362040+ADSLchr2240745836+0.0024016750.99759835
ENST00000543252ENST00000454266GRAP2chr2240362040+ADSLchr2240745836+0.0029022910.99709773
ENST00000543252ENST00000342312GRAP2chr2240362040+ADSLchr2240745836+0.0020149130.9979851
ENST00000344138ENST00000216194GRAP2chr2240362040+ADSLchr2240745836+0.0022820980.997718
ENST00000344138ENST00000454266GRAP2chr2240362040+ADSLchr2240745836+0.0026984810.9973015
ENST00000344138ENST00000342312GRAP2chr2240362040+ADSLchr2240745836+0.0018955110.99810445
ENST00000540310ENST00000216194GRAP2chr2240362040+ADSLchr2240745836+0.0020645080.99793553
ENST00000540310ENST00000454266GRAP2chr2240362040+ADSLchr2240745836+0.0023352750.9976647
ENST00000540310ENST00000342312GRAP2chr2240362040+ADSLchr2240745836+0.0017288880.9982711
ENST00000544756ENST00000216194GRAP2chr2240362040+ADSLchr2240745836+0.0021461670.9978538
ENST00000544756ENST00000454266GRAP2chr2240362040+ADSLchr2240745836+0.0023819790.997618
ENST00000544756ENST00000342312GRAP2chr2240362040+ADSLchr2240745836+0.0017970170.9982029
ENST00000407075ENST00000216194GRAP2chr2240362040+ADSLchr2240745836+0.0022527460.99774724
ENST00000407075ENST00000454266GRAP2chr2240362040+ADSLchr2240745836+0.0024089030.99759114
ENST00000407075ENST00000342312GRAP2chr2240362040+ADSLchr2240745836+0.0018898680.9981102

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Fusion Genomic Features for GRAP2-ADSL


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GRAP2-ADSL


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:40362040/chr22:40745836)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GRAP2

O75791

ADSL

P30566

FUNCTION: Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.FUNCTION: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. {ECO:0000269|PubMed:10888601}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneADSLchr22:40362040chr22:40745836ENST00000216194013111_11251485.0RegionNote=Substrate binding
TgeneADSLchr22:40362040chr22:40745836ENST0000021619401385_8751485.0RegionNote=Substrate binding
TgeneADSLchr22:40362040chr22:40745836ENST00000342312012111_11251426.0RegionNote=Substrate binding
TgeneADSLchr22:40362040chr22:40745836ENST0000034231201285_8751426.0RegionNote=Substrate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGRAP2chr22:40362040chr22:40745836ENST00000344138+181_560331.0DomainSH3 1
HgeneGRAP2chr22:40362040chr22:40745836ENST00000344138+18271_3300331.0DomainSH3 2
HgeneGRAP2chr22:40362040chr22:40745836ENST00000344138+1858_1490331.0DomainSH2
HgeneGRAP2chr22:40362040chr22:40745836ENST00000407075+171_560331.0DomainSH3 1
HgeneGRAP2chr22:40362040chr22:40745836ENST00000407075+17271_3300331.0DomainSH3 2
HgeneGRAP2chr22:40362040chr22:40745836ENST00000407075+1758_1490331.0DomainSH2
TgeneADSLchr22:40362040chr22:40745836ENST0000021619401320_2151485.0RegionNote=Substrate binding%3B shared with neighboring subunit
TgeneADSLchr22:40362040chr22:40745836ENST0000034231201220_2151426.0RegionNote=Substrate binding%3B shared with neighboring subunit


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Fusion Gene Sequence for GRAP2-ADSL


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>34610_34610_1_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000344138_ADSL_chr22_40745836_ENST00000216194_length(transcript)=2459nt_BP=675nt
ACAGACTGCAGGGCTGACTAGGGTTAGTTTGGAGGAGGGAGTAAGAGGTGGGGAGGAGGAGGCACAGTTAATGGATCTGTAAACTTGCAC
CCTCTTTCAGAGTGGTACATGGAAGACAGCACAAAGTGGATCCATACTCTGAAATGCAGTAACTCTGATGCTTGAATTTGTCTCCCTTCT
TGCCAGAAAGGATTCTAATAACTCGGTGTCAAAGCCAAGACATAAACTCAACCCCTTCTCTTCCAAAAGCTTCACGTTACAGCATGGAAG
CTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAACCAAGAGG
AGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCACGAAGGCC
TCTCTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCT
CCATCTCTGTCAGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCC
AGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAA
TCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGC
CACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAAT
GCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGT
TTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTG
AAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGAC
CATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAA
GTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAG
GAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGT
CTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAAC
CGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCC
AAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGC
CAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGT
ATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAG
GTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGT
TGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTAC
CTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTG
AAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCC
TTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACC
TGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGATGAAGTTTGGAACTACAGTAAAT

>34610_34610_1_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000344138_ADSL_chr22_40745836_ENST00000216194_length(amino acids)=494AA_BP=1
MASSSSGPARAPQGTSPSLSGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEE
EKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGK
RCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGA
SVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADT
ILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQL

--------------------------------------------------------------
>34610_34610_2_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000344138_ADSL_chr22_40745836_ENST00000342312_length(transcript)=2274nt_BP=675nt
ACAGACTGCAGGGCTGACTAGGGTTAGTTTGGAGGAGGGAGTAAGAGGTGGGGAGGAGGAGGCACAGTTAATGGATCTGTAAACTTGCAC
CCTCTTTCAGAGTGGTACATGGAAGACAGCACAAAGTGGATCCATACTCTGAAATGCAGTAACTCTGATGCTTGAATTTGTCTCCCTTCT
TGCCAGAAAGGATTCTAATAACTCGGTGTCAAAGCCAAGACATAAACTCAACCCCTTCTCTTCCAAAAGCTTCACGTTACAGCATGGAAG
CTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAACCAAGAGG
AGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCACGAAGGCC
TCTCTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCT
CCATCTCTGTCAGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCC
AGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAA
TCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGC
CACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAAT
GCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGT
TTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTG
AAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGAC
CATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAA
GTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAG
GAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGT
CTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAAC
CGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCC
AAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGC
CAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAG
AGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGT
TACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCG
TTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAG
TCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATA
ACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGATGAAGTTTGGAACTACAGTA

>34610_34610_2_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000344138_ADSL_chr22_40745836_ENST00000342312_length(amino acids)=435AA_BP=1
MASSSSGPARAPQGTSPSLSGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEE
EKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGK
RCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGA
SVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADT

--------------------------------------------------------------
>34610_34610_3_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000344138_ADSL_chr22_40745836_ENST00000454266_length(transcript)=2111nt_BP=675nt
ACAGACTGCAGGGCTGACTAGGGTTAGTTTGGAGGAGGGAGTAAGAGGTGGGGAGGAGGAGGCACAGTTAATGGATCTGTAAACTTGCAC
CCTCTTTCAGAGTGGTACATGGAAGACAGCACAAAGTGGATCCATACTCTGAAATGCAGTAACTCTGATGCTTGAATTTGTCTCCCTTCT
TGCCAGAAAGGATTCTAATAACTCGGTGTCAAAGCCAAGACATAAACTCAACCCCTTCTCTTCCAAAAGCTTCACGTTACAGCATGGAAG
CTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAACCAAGAGG
AGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCACGAAGGCC
TCTCTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCT
CCATCTCTGTCAGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCC
AGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAA
TCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGC
CACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTAGTCTCATTCTGTCAAGGGGC
GTGATCAAGGCTTATTGCAACCTCCGCCTCCCAGGCTCAGACAGCTCTCCTGTCTCAGTCTCCCAACTTGCCAGAGTGATCTCTCGGCTT
GCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGC
TGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACT
GGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTT
AAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTG
CACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATG
CCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCA
TCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTG
AATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACA
GAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCT
GTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCAT
TTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATAT
GAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAA

>34610_34610_3_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000344138_ADSL_chr22_40745836_ENST00000454266_length(amino acids)=508AA_BP=1
MASSSSGPARAPQGTSPSLSGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEE
EKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTSLILSRGVIKAYCNLRLPGSDSSPVSVSQLARVISRLADFAKERASLPTLG
FTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRK
VDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSAN
RRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIER

--------------------------------------------------------------
>34610_34610_4_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000407075_ADSL_chr22_40745836_ENST00000216194_length(transcript)=2486nt_BP=702nt
GATGATGAAAGGAGAAGGGAAAGGCTGCGGATGGCCTTCATTTCCTGCTCCTGGCATCTGGGGATTCCGAGAATGATCCCAGGACCTAGA
TCCTATAGATTCCGGCAGCTCTTCCTGCAAACACAAGCCCTTGTTGTGTGCCTGAGCCTTGCTCTCCGGCCTGGAGACATCCATCTGCCC
ACTCTCCTAGGAACTGCTGATTACCAGGAAGCACCATCGGCTCTGCTGCCCTCCCCCTGGCAGAGAGGCACAATGACCACATTATTTCTC
TTCCAGCTTCACGTTACAGCATGGAAGCTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATG
TTTTGAAGATTTTAAGTAACCAAGAGGAGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCC
AGTTTCCCAAATGGTTTCACGAAGGCCTCTCTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGG
CCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTA
GACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATC
ACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGAT
GTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGAC
AATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAG
GAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAG
GATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGT
TTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATC
ATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACC
GACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAAT
CCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTT
GAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAAC
ATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATG
GCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAA
GGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCT
TCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAG
GTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAAT
GCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTC
TCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCAT
ATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGA
ATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAA

>34610_34610_4_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000407075_ADSL_chr22_40745836_ENST00000216194_length(amino acids)=494AA_BP=1
MASSSSGPARAPQGTSPSLSGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEE
EKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGK
RCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGA
SVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADT
ILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQL

--------------------------------------------------------------
>34610_34610_5_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000407075_ADSL_chr22_40745836_ENST00000342312_length(transcript)=2301nt_BP=702nt
GATGATGAAAGGAGAAGGGAAAGGCTGCGGATGGCCTTCATTTCCTGCTCCTGGCATCTGGGGATTCCGAGAATGATCCCAGGACCTAGA
TCCTATAGATTCCGGCAGCTCTTCCTGCAAACACAAGCCCTTGTTGTGTGCCTGAGCCTTGCTCTCCGGCCTGGAGACATCCATCTGCCC
ACTCTCCTAGGAACTGCTGATTACCAGGAAGCACCATCGGCTCTGCTGCCCTCCCCCTGGCAGAGAGGCACAATGACCACATTATTTCTC
TTCCAGCTTCACGTTACAGCATGGAAGCTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATG
TTTTGAAGATTTTAAGTAACCAAGAGGAGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCC
AGTTTCCCAAATGGTTTCACGAAGGCCTCTCTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGG
CCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTA
GACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATC
ACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGAT
GTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGAC
AATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAG
GAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAG
GATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGT
TTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATC
ATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACC
GACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAAT
CCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTT
GAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAAC
ATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATG
GCCATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATG
AAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTAT
AATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACAT
TTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGG
CATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAG
TGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTA

>34610_34610_5_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000407075_ADSL_chr22_40745836_ENST00000342312_length(amino acids)=435AA_BP=1
MASSSSGPARAPQGTSPSLSGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEE
EKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGK
RCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGA
SVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADT

--------------------------------------------------------------
>34610_34610_6_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000407075_ADSL_chr22_40745836_ENST00000454266_length(transcript)=2138nt_BP=702nt
GATGATGAAAGGAGAAGGGAAAGGCTGCGGATGGCCTTCATTTCCTGCTCCTGGCATCTGGGGATTCCGAGAATGATCCCAGGACCTAGA
TCCTATAGATTCCGGCAGCTCTTCCTGCAAACACAAGCCCTTGTTGTGTGCCTGAGCCTTGCTCTCCGGCCTGGAGACATCCATCTGCCC
ACTCTCCTAGGAACTGCTGATTACCAGGAAGCACCATCGGCTCTGCTGCCCTCCCCCTGGCAGAGAGGCACAATGACCACATTATTTCTC
TTCCAGCTTCACGTTACAGCATGGAAGCTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATG
TTTTGAAGATTTTAAGTAACCAAGAGGAGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCC
AGTTTCCCAAATGGTTTCACGAAGGCCTCTCTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGG
CCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTA
GACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATC
ACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGAT
GTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGAC
AATACTAGTCTCATTCTGTCAAGGGGCGTGATCAAGGCTTATTGCAACCTCCGCCTCCCAGGCTCAGACAGCTCTCCTGTCTCAGTCTCC
CAACTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCA
CAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTG
CGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGAC
AAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCT
GTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAA
AAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACC
CTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAG
GCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATT
CGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATC
AGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTC
AGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAG
GAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAA

>34610_34610_6_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000407075_ADSL_chr22_40745836_ENST00000454266_length(amino acids)=508AA_BP=1
MASSSSGPARAPQGTSPSLSGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEE
EKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTSLILSRGVIKAYCNLRLPGSDSSPVSVSQLARVISRLADFAKERASLPTLG
FTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRK
VDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSAN
RRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIER

--------------------------------------------------------------
>34610_34610_7_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000540310_ADSL_chr22_40745836_ENST00000216194_length(transcript)=2128nt_BP=344nt
TTTGGAGGAGGGAGTAAGAGGTGGGGAGGAGGAGGCACAGTTAATGGATCTGTAAACTTGCACCCTCTTTCAGAGTGGTACATGGAAGAC
AGCACAAAGTGGATCCATACTCTGAAATGCAGTAACTCTGATGCTTGAATTTGTCTCCCTTCTTGCCAGAAAGGATTCTAATAACTCGGT
GTCAAAGCCAAGACATAAACTCAACCCCTTCTCTTCCAAAAGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGG
TAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTA
TCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATG
ATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAG
ACAATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTA
AGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTC
AGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCA
GTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCA
TCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCA
CCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGA
ATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGT
TTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGA
ACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCA
TGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGG
AAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTT
CTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGA
AGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATA
ATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATT
TCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGC
ATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGT
GAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTAT

>34610_34610_7_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000540310_ADSL_chr22_40745836_ENST00000216194_length(amino acids)=503AA_BP=1
MNLSPFLPERILITRCQSQDINSTPSLPKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLEN
IDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQ
PAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEV
LSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICL
AEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDA

--------------------------------------------------------------
>34610_34610_8_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000540310_ADSL_chr22_40745836_ENST00000342312_length(transcript)=1943nt_BP=344nt
TTTGGAGGAGGGAGTAAGAGGTGGGGAGGAGGAGGCACAGTTAATGGATCTGTAAACTTGCACCCTCTTTCAGAGTGGTACATGGAAGAC
AGCACAAAGTGGATCCATACTCTGAAATGCAGTAACTCTGATGCTTGAATTTGTCTCCCTTCTTGCCAGAAAGGATTCTAATAACTCGGT
GTCAAAGCCAAGACATAAACTCAACCCCTTCTCTTCCAAAAGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGG
TAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTA
TCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATG
ATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAG
ACAATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTA
AGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTC
AGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCA
GTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCA
TCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCA
CCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGA
ATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGT
TTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGA
ACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCA
TGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGA
TGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACT
ATAATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCAC
ATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAA
GGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAA
AGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAG

>34610_34610_8_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000540310_ADSL_chr22_40745836_ENST00000342312_length(amino acids)=444AA_BP=1
MNLSPFLPERILITRCQSQDINSTPSLPKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLEN
IDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQ
PAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEV
LSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICL

--------------------------------------------------------------
>34610_34610_9_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000540310_ADSL_chr22_40745836_ENST00000454266_length(transcript)=1780nt_BP=344nt
TTTGGAGGAGGGAGTAAGAGGTGGGGAGGAGGAGGCACAGTTAATGGATCTGTAAACTTGCACCCTCTTTCAGAGTGGTACATGGAAGAC
AGCACAAAGTGGATCCATACTCTGAAATGCAGTAACTCTGATGCTTGAATTTGTCTCCCTTCTTGCCAGAAAGGATTCTAATAACTCGGT
GTCAAAGCCAAGACATAAACTCAACCCCTTCTCTTCCAAAAGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGG
TAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTA
TCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATG
ATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAG
ACAATACTAGTCTCATTCTGTCAAGGGGCGTGATCAAGGCTTATTGCAACCTCCGCCTCCCAGGCTCAGACAGCTCTCCTGTCTCAGTCT
CCCAACTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTG
CACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACC
TGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTG
ACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGT
CTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTG
AAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGA
CCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCG
AGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCA
TTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAA
TCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACT
TCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAG
AGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAA

>34610_34610_9_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000540310_ADSL_chr22_40745836_ENST00000454266_length(amino acids)=517AA_BP=1
MNLSPFLPERILITRCQSQDINSTPSLPKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLEN
IDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTSLILSRGVIKAYCNLRLPGSDSSPVSVSQLARVISRLADFAK
ERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFI
ITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWF
ERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQE

--------------------------------------------------------------
>34610_34610_10_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000543252_ADSL_chr22_40745836_ENST00000216194_length(transcript)=2339nt_BP=555nt
ACAGACTGCAGGGCTGACTAGGGTTAGTTTGGAGGAGGGAGTAAGAGGTGGGGAGGAGGAGGCACAGTTAATGGATCTGTAAACTTGCAC
CCTCTTTCAGAGTGGTACATGGAAGACAGCACAAAGTGGATCCATACTCTGAAATGCAGTAACTCTGATGCTTGAATTTGTCTCCCTTCT
TGCCAGAAAGGATTCTAATAACTCGGTGTCAAAGCCAAGACATAAACTCAACCCCTTCTCTTCCAAAAGCTTCACGTTACAGCATGGAAG
CTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAACCAAGAGG
AGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAGTAATTACTTTCTGTGG
ACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGA
ACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATG
GCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATT
CACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCC
AGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACC
ACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGG
GGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTG
ACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCT
AGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAG
ATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATG
GACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTT
ACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAG
CTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTT
TCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATT
CACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTAT
CCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTA
ATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCC
ATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGT
AGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAG
CAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGAT

>34610_34610_10_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000543252_ADSL_chr22_40745836_ENST00000216194_length(amino acids)=470AA_BP=1
MWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAG
IIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLR
FRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEK
QQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIR
QELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEE

--------------------------------------------------------------
>34610_34610_11_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000543252_ADSL_chr22_40745836_ENST00000342312_length(transcript)=2154nt_BP=555nt
ACAGACTGCAGGGCTGACTAGGGTTAGTTTGGAGGAGGGAGTAAGAGGTGGGGAGGAGGAGGCACAGTTAATGGATCTGTAAACTTGCAC
CCTCTTTCAGAGTGGTACATGGAAGACAGCACAAAGTGGATCCATACTCTGAAATGCAGTAACTCTGATGCTTGAATTTGTCTCCCTTCT
TGCCAGAAAGGATTCTAATAACTCGGTGTCAAAGCCAAGACATAAACTCAACCCCTTCTCTTCCAAAAGCTTCACGTTACAGCATGGAAG
CTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAACCAAGAGG
AGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAGTAATTACTTTCTGTGG
ACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGA
ACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATG
GCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATT
CACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCC
AGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACC
ACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGG
GGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTG
ACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCT
AGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAG
ATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATG
GACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTT
ACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAG
CTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTG
TATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTG
TTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTT
CCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAA
TGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAG
TAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCA

>34610_34610_11_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000543252_ADSL_chr22_40745836_ENST00000342312_length(amino acids)=411AA_BP=1
MWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAG
IIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLR
FRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEK
QQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIR

--------------------------------------------------------------
>34610_34610_12_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000543252_ADSL_chr22_40745836_ENST00000454266_length(transcript)=1991nt_BP=555nt
ACAGACTGCAGGGCTGACTAGGGTTAGTTTGGAGGAGGGAGTAAGAGGTGGGGAGGAGGAGGCACAGTTAATGGATCTGTAAACTTGCAC
CCTCTTTCAGAGTGGTACATGGAAGACAGCACAAAGTGGATCCATACTCTGAAATGCAGTAACTCTGATGCTTGAATTTGTCTCCCTTCT
TGCCAGAAAGGATTCTAATAACTCGGTGTCAAAGCCAAGACATAAACTCAACCCCTTCTCTTCCAAAAGCTTCACGTTACAGCATGGAAG
CTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAACCAAGAGG
AGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAGTAATTACTTTCTGTGG
ACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGA
ACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATG
GCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATT
CACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTAGTCTCATTCTGTCAAGGGGCGTGATCAAGGCTTATTGCAACCTCCGCCTC
CCAGGCTCAGACAGCTCTCCTGTCTCAGTCTCCCAACTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTA
CCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGAT
CTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTT
GAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACA
TATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTG
GCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAA
CGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGAT
GATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTG
GTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCT
GGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGAC
CTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGT
GCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTA
TGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTC

>34610_34610_12_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000543252_ADSL_chr22_40745836_ENST00000454266_length(amino acids)=484AA_BP=1
MWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAG
IIHLGATSCYVGDNTSLILSRGVIKAYCNLRLPGSDSSPVSVSQLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLC
MDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIR
LLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISE
GLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFT

--------------------------------------------------------------
>34610_34610_13_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000544756_ADSL_chr22_40745836_ENST00000216194_length(transcript)=2366nt_BP=582nt
ATTCTATGCTGGACCGGTTCGTGTTAAGTCTGAGTTCCTCAATCGCTGGCTCTCAGGAGCTGTTTGGAAAATTCGTTGCCATGCATGAGT
CGGGGGATTGGTTTTTTTTCCACTGGAAATTGTTAATGGGGACTGCATTAGCGGCCCCTTATCGCTTTGCCTGATAGAGAGACAGCAGGT
TCGCCCAAACAATTCTGGAACCCTGATCACTGCCAATTAGGGGAGTATTGTCTGGCTGACATAATCAACTTCACGTTACAGCATGGAAGC
TGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATGGTTTCACGAAGGCCTCT
CTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCA
TCTCTGTCAGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGA
CAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCA
AACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCAC
TGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCA
CTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTC
ACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAG
CGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCAT
AAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTG
GATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAG
ATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTT
GCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGA
CGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAA
GTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAG
GATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATC
CAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTG
CAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGG
AAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTT
AAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAG
TTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTT
TCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGG
ACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGATGAAGTTTGGAACTACAGTAAATACT

>34610_34610_13_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000544756_ADSL_chr22_40745836_ENST00000216194_length(amino acids)=494AA_BP=1
MASSSSGPARAPQGTSPSLSGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEE
EKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGK
RCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGA
SVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADT
ILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQL

--------------------------------------------------------------
>34610_34610_14_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000544756_ADSL_chr22_40745836_ENST00000342312_length(transcript)=2181nt_BP=582nt
ATTCTATGCTGGACCGGTTCGTGTTAAGTCTGAGTTCCTCAATCGCTGGCTCTCAGGAGCTGTTTGGAAAATTCGTTGCCATGCATGAGT
CGGGGGATTGGTTTTTTTTCCACTGGAAATTGTTAATGGGGACTGCATTAGCGGCCCCTTATCGCTTTGCCTGATAGAGAGACAGCAGGT
TCGCCCAAACAATTCTGGAACCCTGATCACTGCCAATTAGGGGAGTATTGTCTGGCTGACATAATCAACTTCACGTTACAGCATGGAAGC
TGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATGGTTTCACGAAGGCCTCT
CTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCA
TCTCTGTCAGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGA
CAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCA
AACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCAC
TGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCA
CTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTC
ACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAG
CGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCAT
AAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTG
GATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAG
ATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTT
GCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGA
CGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAA
GTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAG
GTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGT
TGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTAC
CTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTG
AAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCC
TTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACC
TGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGATGAAGTTTGGAACTACAGTAAAT

>34610_34610_14_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000544756_ADSL_chr22_40745836_ENST00000342312_length(amino acids)=435AA_BP=1
MASSSSGPARAPQGTSPSLSGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEE
EKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGK
RCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGA
SVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADT

--------------------------------------------------------------
>34610_34610_15_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000544756_ADSL_chr22_40745836_ENST00000454266_length(transcript)=2018nt_BP=582nt
ATTCTATGCTGGACCGGTTCGTGTTAAGTCTGAGTTCCTCAATCGCTGGCTCTCAGGAGCTGTTTGGAAAATTCGTTGCCATGCATGAGT
CGGGGGATTGGTTTTTTTTCCACTGGAAATTGTTAATGGGGACTGCATTAGCGGCCCCTTATCGCTTTGCCTGATAGAGAGACAGCAGGT
TCGCCCAAACAATTCTGGAACCCTGATCACTGCCAATTAGGGGAGTATTGTCTGGCTGACATAATCAACTTCACGTTACAGCATGGAAGC
TGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATGGTTTCACGAAGGCCTCT
CTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCA
TCTCTGTCAGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGA
CAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCA
AACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCAC
TGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTAGTCTCATTCTGTCAAGGGGCGTG
ATCAAGGCTTATTGCAACCTCCGCCTCCCAGGCTCAGACAGCTCTCCTGTCTCAGTCTCCCAACTTGCCAGAGTGATCTCTCGGCTTGCC
GACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGT
CTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGC
ACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAG
AGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCAC
AAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCA
TATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCT
GTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAAT
ACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAG
AACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTG
GTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTA
CTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAA
AGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTG

>34610_34610_15_GRAP2-ADSL_GRAP2_chr22_40362040_ENST00000544756_ADSL_chr22_40745836_ENST00000454266_length(amino acids)=508AA_BP=1
MASSSSGPARAPQGTSPSLSGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEE
EKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTSLILSRGVIKAYCNLRLPGSDSSPVSVSQLARVISRLADFAKERASLPTLG
FTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRK
VDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSAN
RRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIER

--------------------------------------------------------------

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Fusion Gene PPI Analysis for GRAP2-ADSL


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GRAP2-ADSL


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GRAP2-ADSL


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource