FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:GRB2-VMP1 (FusionGDB2 ID:34656)

Fusion Gene Summary for GRB2-VMP1

check button Fusion gene summary
Fusion gene informationFusion gene name: GRB2-VMP1
Fusion gene ID: 34656
HgeneTgene
Gene symbol

GRB2

VMP1

Gene ID

2885

81671

Gene namegrowth factor receptor bound protein 2vacuole membrane protein 1
SynonymsASH|EGFRBP-GRB2|Grb3-3|MST084|MSTP084|NCKAP2EPG3|TANGO5|TMEM49
Cytomap

17q25.1

17q23.1

Type of geneprotein-codingprotein-coding
Descriptiongrowth factor receptor-bound protein 2HT027SH2/SH3 adapter GRB2abundant SRC homologyepidermal growth factor receptor-binding protein GRB2epididymis secretory sperm binding proteingrowth factor receptor-bound protein 3protein Ashvacuole membrane protein 1ectopic P-granules autophagy protein 3 homologtransmembrane protein 49transport and golgi organization 5 homolog
Modification date2020032720200327
UniProtAcc

P62993

.
Ensembl transtripts involved in fusion geneENST00000316615, ENST00000316804, 
ENST00000392562, ENST00000392563, 
ENST00000392564, ENST00000578961, 
ENST00000462266, 		ENST00000536180, 
ENST00000539763, ENST00000545362, 
ENST00000588617, ENST00000262291, 
ENST00000537567, 
Fusion gene scores* DoF score18 X 13 X 11=257442 X 34 X 19=27132
# samples 25151
** MAII scorelog2(25/2574*10)=-3.36401205355861
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(151/27132*10)=-4.16737494326024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GRB2 [Title/Abstract] AND VMP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGRB2(73389632)-VMP1(57842332), # samples:3
Anticipated loss of major functional domain due to fusion event.GRB2-VMP1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across GRB2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across VMP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-D9-A1JW-06AGRB2chr17

73389632

-VMP1chr17

57842332

+
ChimerDB4SKCMTCGA-D9-A1JWGRB2chr17

73389631

-VMP1chr17

57842331

+


Top

Fusion Gene ORF analysis for GRB2-VMP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000316615ENST00000536180GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-5UTRENST00000316615ENST00000536180GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-5UTRENST00000316615ENST00000539763GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-5UTRENST00000316615ENST00000539763GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-5UTRENST00000316804ENST00000536180GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-5UTRENST00000316804ENST00000536180GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-5UTRENST00000316804ENST00000539763GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-5UTRENST00000316804ENST00000539763GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-5UTRENST00000392562ENST00000536180GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-5UTRENST00000392562ENST00000536180GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-5UTRENST00000392562ENST00000539763GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-5UTRENST00000392562ENST00000539763GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-5UTRENST00000392563ENST00000536180GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-5UTRENST00000392563ENST00000536180GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-5UTRENST00000392563ENST00000539763GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-5UTRENST00000392563ENST00000539763GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-5UTRENST00000392564ENST00000536180GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-5UTRENST00000392564ENST00000536180GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-5UTRENST00000392564ENST00000539763GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-5UTRENST00000392564ENST00000539763GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-5UTRENST00000578961ENST00000536180GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-5UTRENST00000578961ENST00000536180GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-5UTRENST00000578961ENST00000539763GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-5UTRENST00000578961ENST00000539763GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-intronENST00000316615ENST00000545362GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-intronENST00000316615ENST00000545362GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-intronENST00000316615ENST00000588617GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-intronENST00000316615ENST00000588617GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-intronENST00000316804ENST00000545362GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-intronENST00000316804ENST00000545362GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-intronENST00000316804ENST00000588617GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-intronENST00000316804ENST00000588617GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-intronENST00000392562ENST00000545362GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-intronENST00000392562ENST00000545362GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-intronENST00000392562ENST00000588617GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-intronENST00000392562ENST00000588617GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-intronENST00000392563ENST00000545362GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-intronENST00000392563ENST00000545362GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-intronENST00000392563ENST00000588617GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-intronENST00000392563ENST00000588617GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-intronENST00000392564ENST00000545362GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-intronENST00000392564ENST00000545362GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-intronENST00000392564ENST00000588617GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-intronENST00000392564ENST00000588617GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-intronENST00000578961ENST00000545362GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-intronENST00000578961ENST00000545362GRB2chr17

73389631

-VMP1chr17

57842331

+
5CDS-intronENST00000578961ENST00000588617GRB2chr17

73389632

-VMP1chr17

57842332

+
5CDS-intronENST00000578961ENST00000588617GRB2chr17

73389631

-VMP1chr17

57842331

+
Frame-shiftENST00000316615ENST00000262291GRB2chr17

73389632

-VMP1chr17

57842332

+
Frame-shiftENST00000316615ENST00000262291GRB2chr17

73389631

-VMP1chr17

57842331

+
Frame-shiftENST00000316615ENST00000537567GRB2chr17

73389632

-VMP1chr17

57842332

+
Frame-shiftENST00000316615ENST00000537567GRB2chr17

73389631

-VMP1chr17

57842331

+
Frame-shiftENST00000316804ENST00000262291GRB2chr17

73389632

-VMP1chr17

57842332

+
Frame-shiftENST00000316804ENST00000262291GRB2chr17

73389631

-VMP1chr17

57842331

+
Frame-shiftENST00000316804ENST00000537567GRB2chr17

73389632

-VMP1chr17

57842332

+
Frame-shiftENST00000316804ENST00000537567GRB2chr17

73389631

-VMP1chr17

57842331

+
Frame-shiftENST00000392562ENST00000262291GRB2chr17

73389632

-VMP1chr17

57842332

+
Frame-shiftENST00000392562ENST00000262291GRB2chr17

73389631

-VMP1chr17

57842331

+
Frame-shiftENST00000392562ENST00000537567GRB2chr17

73389632

-VMP1chr17

57842332

+
Frame-shiftENST00000392562ENST00000537567GRB2chr17

73389631

-VMP1chr17

57842331

+
In-frameENST00000392563ENST00000262291GRB2chr17

73389632

-VMP1chr17

57842332

+
In-frameENST00000392563ENST00000262291GRB2chr17

73389631

-VMP1chr17

57842331

+
In-frameENST00000392563ENST00000537567GRB2chr17

73389632

-VMP1chr17

57842332

+
In-frameENST00000392563ENST00000537567GRB2chr17

73389631

-VMP1chr17

57842331

+
In-frameENST00000392564ENST00000262291GRB2chr17

73389632

-VMP1chr17

57842332

+
In-frameENST00000392564ENST00000262291GRB2chr17

73389631

-VMP1chr17

57842331

+
In-frameENST00000392564ENST00000537567GRB2chr17

73389632

-VMP1chr17

57842332

+
In-frameENST00000392564ENST00000537567GRB2chr17

73389631

-VMP1chr17

57842331

+
In-frameENST00000578961ENST00000262291GRB2chr17

73389632

-VMP1chr17

57842332

+
In-frameENST00000578961ENST00000262291GRB2chr17

73389631

-VMP1chr17

57842331

+
In-frameENST00000578961ENST00000537567GRB2chr17

73389632

-VMP1chr17

57842332

+
In-frameENST00000578961ENST00000537567GRB2chr17

73389631

-VMP1chr17

57842331

+
intron-3CDSENST00000462266ENST00000262291GRB2chr17

73389632

-VMP1chr17

57842332

+
intron-3CDSENST00000462266ENST00000262291GRB2chr17

73389631

-VMP1chr17

57842331

+
intron-3CDSENST00000462266ENST00000537567GRB2chr17

73389632

-VMP1chr17

57842332

+
intron-3CDSENST00000462266ENST00000537567GRB2chr17

73389631

-VMP1chr17

57842331

+
intron-5UTRENST00000462266ENST00000536180GRB2chr17

73389632

-VMP1chr17

57842332

+
intron-5UTRENST00000462266ENST00000536180GRB2chr17

73389631

-VMP1chr17

57842331

+
intron-5UTRENST00000462266ENST00000539763GRB2chr17

73389632

-VMP1chr17

57842332

+
intron-5UTRENST00000462266ENST00000539763GRB2chr17

73389631

-VMP1chr17

57842331

+
intron-intronENST00000462266ENST00000545362GRB2chr17

73389632

-VMP1chr17

57842332

+
intron-intronENST00000462266ENST00000545362GRB2chr17

73389631

-VMP1chr17

57842331

+
intron-intronENST00000462266ENST00000588617GRB2chr17

73389632

-VMP1chr17

57842332

+
intron-intronENST00000462266ENST00000588617GRB2chr17

73389631

-VMP1chr17

57842331

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000392563GRB2chr1773389632-ENST00000262291VMP1chr1757842332+209410628912294
ENST00000392563GRB2chr1773389632-ENST00000537567VMP1chr1757842332+117310628912294
ENST00000392564GRB2chr1773389632-ENST00000262291VMP1chr1757842332+23023142361120294
ENST00000392564GRB2chr1773389632-ENST00000537567VMP1chr1757842332+13813142361120294
ENST00000578961GRB2chr1773389632-ENST00000262291VMP1chr1757842332+22412531751059294
ENST00000578961GRB2chr1773389632-ENST00000537567VMP1chr1757842332+13202531751059294
ENST00000392563GRB2chr1773389631-ENST00000262291VMP1chr1757842331+209410628912294
ENST00000392563GRB2chr1773389631-ENST00000537567VMP1chr1757842331+117310628912294
ENST00000392564GRB2chr1773389631-ENST00000262291VMP1chr1757842331+23023142361120294
ENST00000392564GRB2chr1773389631-ENST00000537567VMP1chr1757842331+13813142361120294
ENST00000578961GRB2chr1773389631-ENST00000262291VMP1chr1757842331+22412531751059294
ENST00000578961GRB2chr1773389631-ENST00000537567VMP1chr1757842331+13202531751059294

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000392563ENST00000262291GRB2chr1773389632-VMP1chr1757842332+0.0006918520.9993081
ENST00000392563ENST00000537567GRB2chr1773389632-VMP1chr1757842332+0.0015582940.99844176
ENST00000392564ENST00000262291GRB2chr1773389632-VMP1chr1757842332+0.001134560.9988655
ENST00000392564ENST00000537567GRB2chr1773389632-VMP1chr1757842332+0.0029519170.9970481
ENST00000578961ENST00000262291GRB2chr1773389632-VMP1chr1757842332+0.0010535660.9989465
ENST00000578961ENST00000537567GRB2chr1773389632-VMP1chr1757842332+0.0029712840.99702877
ENST00000392563ENST00000262291GRB2chr1773389631-VMP1chr1757842331+0.0006918520.9993081
ENST00000392563ENST00000537567GRB2chr1773389631-VMP1chr1757842331+0.0015582940.99844176
ENST00000392564ENST00000262291GRB2chr1773389631-VMP1chr1757842331+0.001134560.9988655
ENST00000392564ENST00000537567GRB2chr1773389631-VMP1chr1757842331+0.0029519170.9970481
ENST00000578961ENST00000262291GRB2chr1773389631-VMP1chr1757842331+0.0010535660.9989465
ENST00000578961ENST00000537567GRB2chr1773389631-VMP1chr1757842331+0.0029712840.99702877

Top

Fusion Genomic Features for GRB2-VMP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
GRB2chr1773389631-VMP1chr1757842331+2.16E-101
GRB2chr1773389631-VMP1chr1757842331+2.16E-101
GRB2chr1773389631-VMP1chr1757842331+2.16E-101
GRB2chr1773389631-VMP1chr1757842331+2.16E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for GRB2-VMP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:73389632/chr17:57842332)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GRB2

P62993

.
FUNCTION: Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. {ECO:0000269|PubMed:1322798, ECO:0000269|PubMed:19815557}.; FUNCTION: [Isoform 2]: Does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death. {ECO:0000269|PubMed:8178156}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneVMP1chr17:73389631chr17:57842331ENST00000262291412173_316138407.0RegionVTT domain
TgeneVMP1chr17:73389632chr17:57842332ENST00000262291412173_316138407.0RegionVTT domain
TgeneVMP1chr17:73389631chr17:57842331ENST00000262291412272_273138407.0Topological domainCytoplasmic
TgeneVMP1chr17:73389631chr17:57842331ENST00000262291412295_305138407.0Topological domainExtracellular
TgeneVMP1chr17:73389631chr17:57842331ENST00000262291412327_363138407.0Topological domainCytoplasmic
TgeneVMP1chr17:73389631chr17:57842331ENST00000262291412385_406138407.0Topological domainExtracellular
TgeneVMP1chr17:73389632chr17:57842332ENST00000262291412272_273138407.0Topological domainCytoplasmic
TgeneVMP1chr17:73389632chr17:57842332ENST00000262291412295_305138407.0Topological domainExtracellular
TgeneVMP1chr17:73389632chr17:57842332ENST00000262291412327_363138407.0Topological domainCytoplasmic
TgeneVMP1chr17:73389632chr17:57842332ENST00000262291412385_406138407.0Topological domainExtracellular
TgeneVMP1chr17:73389631chr17:57842331ENST00000262291412251_271138407.0TransmembraneHelical
TgeneVMP1chr17:73389631chr17:57842331ENST00000262291412274_294138407.0TransmembraneHelical
TgeneVMP1chr17:73389631chr17:57842331ENST00000262291412306_326138407.0TransmembraneHelical
TgeneVMP1chr17:73389631chr17:57842331ENST00000262291412364_384138407.0TransmembraneHelical
TgeneVMP1chr17:73389632chr17:57842332ENST00000262291412251_271138407.0TransmembraneHelical
TgeneVMP1chr17:73389632chr17:57842332ENST00000262291412274_294138407.0TransmembraneHelical
TgeneVMP1chr17:73389632chr17:57842332ENST00000262291412306_326138407.0TransmembraneHelical
TgeneVMP1chr17:73389632chr17:57842332ENST00000262291412364_384138407.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGRB2chr17:73389631chr17:57842331ENST00000316615-25156_21526177.0DomainSH3 2
HgeneGRB2chr17:73389631chr17:57842331ENST00000316615-251_5826177.0DomainSH3 1
HgeneGRB2chr17:73389631chr17:57842331ENST00000316615-2560_15226177.0DomainSH2
HgeneGRB2chr17:73389631chr17:57842331ENST00000316804-26156_21526218.0DomainSH3 2
HgeneGRB2chr17:73389631chr17:57842331ENST00000316804-261_5826218.0DomainSH3 1
HgeneGRB2chr17:73389631chr17:57842331ENST00000316804-2660_15226218.0DomainSH2
HgeneGRB2chr17:73389631chr17:57842331ENST00000392562-26156_21526218.0DomainSH3 2
HgeneGRB2chr17:73389631chr17:57842331ENST00000392562-261_5826218.0DomainSH3 1
HgeneGRB2chr17:73389631chr17:57842331ENST00000392562-2660_15226218.0DomainSH2
HgeneGRB2chr17:73389631chr17:57842331ENST00000392563-14156_21526177.0DomainSH3 2
HgeneGRB2chr17:73389631chr17:57842331ENST00000392563-141_5826177.0DomainSH3 1
HgeneGRB2chr17:73389631chr17:57842331ENST00000392563-1460_15226177.0DomainSH2
HgeneGRB2chr17:73389631chr17:57842331ENST00000392564-15156_21526218.0DomainSH3 2
HgeneGRB2chr17:73389631chr17:57842331ENST00000392564-151_5826218.0DomainSH3 1
HgeneGRB2chr17:73389631chr17:57842331ENST00000392564-1560_15226218.0DomainSH2
HgeneGRB2chr17:73389632chr17:57842332ENST00000316615-25156_21526177.0DomainSH3 2
HgeneGRB2chr17:73389632chr17:57842332ENST00000316615-251_5826177.0DomainSH3 1
HgeneGRB2chr17:73389632chr17:57842332ENST00000316615-2560_15226177.0DomainSH2
HgeneGRB2chr17:73389632chr17:57842332ENST00000316804-26156_21526218.0DomainSH3 2
HgeneGRB2chr17:73389632chr17:57842332ENST00000316804-261_5826218.0DomainSH3 1
HgeneGRB2chr17:73389632chr17:57842332ENST00000316804-2660_15226218.0DomainSH2
HgeneGRB2chr17:73389632chr17:57842332ENST00000392562-26156_21526218.0DomainSH3 2
HgeneGRB2chr17:73389632chr17:57842332ENST00000392562-261_5826218.0DomainSH3 1
HgeneGRB2chr17:73389632chr17:57842332ENST00000392562-2660_15226218.0DomainSH2
HgeneGRB2chr17:73389632chr17:57842332ENST00000392563-14156_21526177.0DomainSH3 2
HgeneGRB2chr17:73389632chr17:57842332ENST00000392563-141_5826177.0DomainSH3 1
HgeneGRB2chr17:73389632chr17:57842332ENST00000392563-1460_15226177.0DomainSH2
HgeneGRB2chr17:73389632chr17:57842332ENST00000392564-15156_21526218.0DomainSH3 2
HgeneGRB2chr17:73389632chr17:57842332ENST00000392564-151_5826218.0DomainSH3 1
HgeneGRB2chr17:73389632chr17:57842332ENST00000392564-1560_15226218.0DomainSH2
TgeneVMP1chr17:73389631chr17:57842331ENST00000262291412131_250138407.0Topological domainExtracellular
TgeneVMP1chr17:73389631chr17:57842331ENST000002622914122_43138407.0Topological domainCytoplasmic
TgeneVMP1chr17:73389631chr17:57842331ENST0000026229141265_77138407.0Topological domainExtracellular
TgeneVMP1chr17:73389631chr17:57842331ENST0000026229141299_109138407.0Topological domainCytoplasmic
TgeneVMP1chr17:73389632chr17:57842332ENST00000262291412131_250138407.0Topological domainExtracellular
TgeneVMP1chr17:73389632chr17:57842332ENST000002622914122_43138407.0Topological domainCytoplasmic
TgeneVMP1chr17:73389632chr17:57842332ENST0000026229141265_77138407.0Topological domainExtracellular
TgeneVMP1chr17:73389632chr17:57842332ENST0000026229141299_109138407.0Topological domainCytoplasmic
TgeneVMP1chr17:73389631chr17:57842331ENST00000262291412110_130138407.0TransmembraneHelical
TgeneVMP1chr17:73389631chr17:57842331ENST0000026229141244_64138407.0TransmembraneHelical
TgeneVMP1chr17:73389631chr17:57842331ENST0000026229141278_98138407.0TransmembraneHelical
TgeneVMP1chr17:73389632chr17:57842332ENST00000262291412110_130138407.0TransmembraneHelical
TgeneVMP1chr17:73389632chr17:57842332ENST0000026229141244_64138407.0TransmembraneHelical
TgeneVMP1chr17:73389632chr17:57842332ENST0000026229141278_98138407.0TransmembraneHelical


Top

Fusion Gene Sequence for GRB2-VMP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>34656_34656_1_GRB2-VMP1_GRB2_chr17_73389631_ENST00000392563_VMP1_chr17_57842331_ENST00000262291_length(transcript)=2094nt_BP=106nt
GGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAG
GGGGGACATCCTCAAGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCC
TGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCAT
GTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGA
GTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACA
GAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGT
ACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAG
CAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGA
GGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGT
TGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGA
GAAAACTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGG
AAAATTCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTT
CTGTGCTAAGGTAAGGTATCCACCCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGAATGTGATGTTCAGCAGCAAACTTGCAACAG
ACTGGCCTTCTGTTTGTTACTTTCAAAAGGCCCACATGATACAATTAGAGAATTCCCACCGCACAAAAAAAGTTCCTAAGTATGTTAAAT
ATGTCAAGCTTTTTAGGCTTGTCACAAATGATTGCTTTGTTTTCCTAAGTCATCAAAATGTATATAAATTATCTAGATTGGATAACAGTC
TTGCATGTTTATCATGTTACAATTTAATATTCCATCCTGCCCAACCCTTCCTCTCCCATCCTCAAAAAAGGGCCATTTTATGATGCATTG
CACACCCTCTGGGGAAATTGATCTTTAAATTTTGAGACAGTATAAGGAAAATCTGGTTGGTGTCTTACAAGTGAGCTGACACCATTTTTT
ATTCTGTGTATTTAGAATGAAGTCTTGAAAAAAACTTTATAAAGACATCTTTAATCATTCCAAAATTGTGTCCGTTTTCTTGAGCGTTTT
GATTTTTTACTTTTAGCTTATACCAGCTGAATGGCAGCCTTGCCTAATCCACCTACAACAAGAATTTCTTAAGCTTTCTTTTATTTGCAT
GAGAGAGCCACTACCAAGGCATGTTTTGTTATGCTGAAACTGGGCTGCTGCATACTGCTAAATGGCACCTCTGGGATTGGCCTACCTGGG
GATTTCTTGGTTTGTGAAAACAGGAGAGGAGAAATATCTCATACAAGTGAAAGGATACTGGAGAGAGAAATTACCCATTTCTAAAAAAAA
ACCACACTCTGTCGTATCTGTGTTAATGTTTTCTAGCATGTACTCTGGTTTCAACAGACACAAATTTATATGTTAACCCAGTTTTCTTGC
CGTTCTGTAAGTGTTTTATTCTTAGTGTGATTTTTTTCCATTGGGATGTTTTTGATTGAACTTGTTCATTTTGTTTTGCTTGGGAGGAAA

>34656_34656_1_GRB2-VMP1_GRB2_chr17_73389631_ENST00000392563_VMP1_chr17_57842331_ENST00000262291_length(amino acids)=294AA_BP=24
MEAIAKYDFKATADDELSFKRGDILKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGE
LPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGAT
LIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILS

--------------------------------------------------------------
>34656_34656_2_GRB2-VMP1_GRB2_chr17_73389631_ENST00000392563_VMP1_chr17_57842331_ENST00000537567_length(transcript)=1173nt_BP=106nt
GGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAG
GGGGGACATCCTCAAGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCC
TGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCAT
GTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGA
GTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACA
GAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGT
ACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAG
CAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGA
GGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGT
TGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGA
GAAAACTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGG
AAAATTCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTT
CTGTGCTAAGGTAAGGTATCCACCCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGAATGTGATGTTCAGCAGCAAACTTGCAACAG

>34656_34656_2_GRB2-VMP1_GRB2_chr17_73389631_ENST00000392563_VMP1_chr17_57842331_ENST00000537567_length(amino acids)=294AA_BP=24
MEAIAKYDFKATADDELSFKRGDILKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGE
LPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGAT
LIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILS

--------------------------------------------------------------
>34656_34656_3_GRB2-VMP1_GRB2_chr17_73389631_ENST00000392564_VMP1_chr17_57842331_ENST00000262291_length(transcript)=2302nt_BP=314nt
GAGCCAGGGGGCGTGGGGGCTGGGACAGCAGGCCGATTGGCAGGGCGGGGTTGCCTTCAATCCTGGCCACTGCTCTTAATCGTCCCTCTC
CTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAG
CAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTA
CTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATT
CAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCA
TCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCC
TCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGG
CCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGG
CTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCC
AGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTC
TGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGT
TGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAAC
GAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTT
AAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCC
ATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCACCCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGAAT
GTGATGTTCAGCAGCAAACTTGCAACAGACTGGCCTTCTGTTTGTTACTTTCAAAAGGCCCACATGATACAATTAGAGAATTCCCACCGC
ACAAAAAAAGTTCCTAAGTATGTTAAATATGTCAAGCTTTTTAGGCTTGTCACAAATGATTGCTTTGTTTTCCTAAGTCATCAAAATGTA
TATAAATTATCTAGATTGGATAACAGTCTTGCATGTTTATCATGTTACAATTTAATATTCCATCCTGCCCAACCCTTCCTCTCCCATCCT
CAAAAAAGGGCCATTTTATGATGCATTGCACACCCTCTGGGGAAATTGATCTTTAAATTTTGAGACAGTATAAGGAAAATCTGGTTGGTG
TCTTACAAGTGAGCTGACACCATTTTTTATTCTGTGTATTTAGAATGAAGTCTTGAAAAAAACTTTATAAAGACATCTTTAATCATTCCA
AAATTGTGTCCGTTTTCTTGAGCGTTTTGATTTTTTACTTTTAGCTTATACCAGCTGAATGGCAGCCTTGCCTAATCCACCTACAACAAG
AATTTCTTAAGCTTTCTTTTATTTGCATGAGAGAGCCACTACCAAGGCATGTTTTGTTATGCTGAAACTGGGCTGCTGCATACTGCTAAA
TGGCACCTCTGGGATTGGCCTACCTGGGGATTTCTTGGTTTGTGAAAACAGGAGAGGAGAAATATCTCATACAAGTGAAAGGATACTGGA
GAGAGAAATTACCCATTTCTAAAAAAAAACCACACTCTGTCGTATCTGTGTTAATGTTTTCTAGCATGTACTCTGGTTTCAACAGACACA
AATTTATATGTTAACCCAGTTTTCTTGCCGTTCTGTAAGTGTTTTATTCTTAGTGTGATTTTTTTCCATTGGGATGTTTTTGATTGAACT

>34656_34656_3_GRB2-VMP1_GRB2_chr17_73389631_ENST00000392564_VMP1_chr17_57842331_ENST00000262291_length(amino acids)=294AA_BP=24
MEAIAKYDFKATADDELSFKRGDILKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGE
LPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGAT
LIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILS

--------------------------------------------------------------
>34656_34656_4_GRB2-VMP1_GRB2_chr17_73389631_ENST00000392564_VMP1_chr17_57842331_ENST00000537567_length(transcript)=1381nt_BP=314nt
GAGCCAGGGGGCGTGGGGGCTGGGACAGCAGGCCGATTGGCAGGGCGGGGTTGCCTTCAATCCTGGCCACTGCTCTTAATCGTCCCTCTC
CTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAG
CAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTA
CTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATT
CAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCA
TCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCC
TCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGG
CCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGG
CTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCC
AGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTC
TGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGT
TGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAAC
GAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTT
AAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCC
ATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCACCCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGAAT

>34656_34656_4_GRB2-VMP1_GRB2_chr17_73389631_ENST00000392564_VMP1_chr17_57842331_ENST00000537567_length(amino acids)=294AA_BP=24
MEAIAKYDFKATADDELSFKRGDILKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGE
LPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGAT
LIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILS

--------------------------------------------------------------
>34656_34656_5_GRB2-VMP1_GRB2_chr17_73389631_ENST00000578961_VMP1_chr17_57842331_ENST00000262291_length(transcript)=2241nt_BP=253nt
CCTGGCCACTGCTCTTAATCGTCCCTCTCCTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAG
GCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGA
AGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGGTCCACATATAGCCTC
AGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCAC
TGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCC
TCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGC
AGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGC
TTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAAT
TGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCAT
TGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGA
AATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCAT
TAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAGTTTTAAACTG
CAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTATCAATTTTTA
CAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCACCCTCGATGCA
ATCCACCTTGTGTTTTCTTAGGGTGGAATGTGATGTTCAGCAGCAAACTTGCAACAGACTGGCCTTCTGTTTGTTACTTTCAAAAGGCCC
ACATGATACAATTAGAGAATTCCCACCGCACAAAAAAAGTTCCTAAGTATGTTAAATATGTCAAGCTTTTTAGGCTTGTCACAAATGATT
GCTTTGTTTTCCTAAGTCATCAAAATGTATATAAATTATCTAGATTGGATAACAGTCTTGCATGTTTATCATGTTACAATTTAATATTCC
ATCCTGCCCAACCCTTCCTCTCCCATCCTCAAAAAAGGGCCATTTTATGATGCATTGCACACCCTCTGGGGAAATTGATCTTTAAATTTT
GAGACAGTATAAGGAAAATCTGGTTGGTGTCTTACAAGTGAGCTGACACCATTTTTTATTCTGTGTATTTAGAATGAAGTCTTGAAAAAA
ACTTTATAAAGACATCTTTAATCATTCCAAAATTGTGTCCGTTTTCTTGAGCGTTTTGATTTTTTACTTTTAGCTTATACCAGCTGAATG
GCAGCCTTGCCTAATCCACCTACAACAAGAATTTCTTAAGCTTTCTTTTATTTGCATGAGAGAGCCACTACCAAGGCATGTTTTGTTATG
CTGAAACTGGGCTGCTGCATACTGCTAAATGGCACCTCTGGGATTGGCCTACCTGGGGATTTCTTGGTTTGTGAAAACAGGAGAGGAGAA
ATATCTCATACAAGTGAAAGGATACTGGAGAGAGAAATTACCCATTTCTAAAAAAAAACCACACTCTGTCGTATCTGTGTTAATGTTTTC
TAGCATGTACTCTGGTTTCAACAGACACAAATTTATATGTTAACCCAGTTTTCTTGCCGTTCTGTAAGTGTTTTATTCTTAGTGTGATTT

>34656_34656_5_GRB2-VMP1_GRB2_chr17_73389631_ENST00000578961_VMP1_chr17_57842331_ENST00000262291_length(amino acids)=294AA_BP=24
MEAIAKYDFKATADDELSFKRGDILKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGE
LPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGAT
LIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILS

--------------------------------------------------------------
>34656_34656_6_GRB2-VMP1_GRB2_chr17_73389631_ENST00000578961_VMP1_chr17_57842331_ENST00000537567_length(transcript)=1320nt_BP=253nt
CCTGGCCACTGCTCTTAATCGTCCCTCTCCTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAG
GCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGA
AGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGGTCCACATATAGCCTC
AGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCAC
TGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCC
TCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGC
AGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGC
TTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAAT
TGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCAT
TGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGA
AATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCAT
TAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAGTTTTAAACTG
CAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTATCAATTTTTA
CAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCACCCTCGATGCA

>34656_34656_6_GRB2-VMP1_GRB2_chr17_73389631_ENST00000578961_VMP1_chr17_57842331_ENST00000537567_length(amino acids)=294AA_BP=24
MEAIAKYDFKATADDELSFKRGDILKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGE
LPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGAT
LIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILS

--------------------------------------------------------------
>34656_34656_7_GRB2-VMP1_GRB2_chr17_73389632_ENST00000392563_VMP1_chr17_57842332_ENST00000262291_length(transcript)=2094nt_BP=106nt
GGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAG
GGGGGACATCCTCAAGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCC
TGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCAT
GTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGA
GTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACA
GAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGT
ACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAG
CAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGA
GGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGT
TGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGA
GAAAACTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGG
AAAATTCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTT
CTGTGCTAAGGTAAGGTATCCACCCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGAATGTGATGTTCAGCAGCAAACTTGCAACAG
ACTGGCCTTCTGTTTGTTACTTTCAAAAGGCCCACATGATACAATTAGAGAATTCCCACCGCACAAAAAAAGTTCCTAAGTATGTTAAAT
ATGTCAAGCTTTTTAGGCTTGTCACAAATGATTGCTTTGTTTTCCTAAGTCATCAAAATGTATATAAATTATCTAGATTGGATAACAGTC
TTGCATGTTTATCATGTTACAATTTAATATTCCATCCTGCCCAACCCTTCCTCTCCCATCCTCAAAAAAGGGCCATTTTATGATGCATTG
CACACCCTCTGGGGAAATTGATCTTTAAATTTTGAGACAGTATAAGGAAAATCTGGTTGGTGTCTTACAAGTGAGCTGACACCATTTTTT
ATTCTGTGTATTTAGAATGAAGTCTTGAAAAAAACTTTATAAAGACATCTTTAATCATTCCAAAATTGTGTCCGTTTTCTTGAGCGTTTT
GATTTTTTACTTTTAGCTTATACCAGCTGAATGGCAGCCTTGCCTAATCCACCTACAACAAGAATTTCTTAAGCTTTCTTTTATTTGCAT
GAGAGAGCCACTACCAAGGCATGTTTTGTTATGCTGAAACTGGGCTGCTGCATACTGCTAAATGGCACCTCTGGGATTGGCCTACCTGGG
GATTTCTTGGTTTGTGAAAACAGGAGAGGAGAAATATCTCATACAAGTGAAAGGATACTGGAGAGAGAAATTACCCATTTCTAAAAAAAA
ACCACACTCTGTCGTATCTGTGTTAATGTTTTCTAGCATGTACTCTGGTTTCAACAGACACAAATTTATATGTTAACCCAGTTTTCTTGC
CGTTCTGTAAGTGTTTTATTCTTAGTGTGATTTTTTTCCATTGGGATGTTTTTGATTGAACTTGTTCATTTTGTTTTGCTTGGGAGGAAA

>34656_34656_7_GRB2-VMP1_GRB2_chr17_73389632_ENST00000392563_VMP1_chr17_57842332_ENST00000262291_length(amino acids)=294AA_BP=24
MEAIAKYDFKATADDELSFKRGDILKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGE
LPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGAT
LIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILS

--------------------------------------------------------------
>34656_34656_8_GRB2-VMP1_GRB2_chr17_73389632_ENST00000392563_VMP1_chr17_57842332_ENST00000537567_length(transcript)=1173nt_BP=106nt
GGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAG
GGGGGACATCCTCAAGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCC
TGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCAT
GTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGA
GTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACA
GAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGT
ACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAG
CAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGA
GGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGT
TGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGA
GAAAACTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGG
AAAATTCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTT
CTGTGCTAAGGTAAGGTATCCACCCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGAATGTGATGTTCAGCAGCAAACTTGCAACAG

>34656_34656_8_GRB2-VMP1_GRB2_chr17_73389632_ENST00000392563_VMP1_chr17_57842332_ENST00000537567_length(amino acids)=294AA_BP=24
MEAIAKYDFKATADDELSFKRGDILKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGE
LPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGAT
LIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILS

--------------------------------------------------------------
>34656_34656_9_GRB2-VMP1_GRB2_chr17_73389632_ENST00000392564_VMP1_chr17_57842332_ENST00000262291_length(transcript)=2302nt_BP=314nt
GAGCCAGGGGGCGTGGGGGCTGGGACAGCAGGCCGATTGGCAGGGCGGGGTTGCCTTCAATCCTGGCCACTGCTCTTAATCGTCCCTCTC
CTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAG
CAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTA
CTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATT
CAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCA
TCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCC
TCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGG
CCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGG
CTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCC
AGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTC
TGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGT
TGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAAC
GAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTT
AAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCC
ATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCACCCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGAAT
GTGATGTTCAGCAGCAAACTTGCAACAGACTGGCCTTCTGTTTGTTACTTTCAAAAGGCCCACATGATACAATTAGAGAATTCCCACCGC
ACAAAAAAAGTTCCTAAGTATGTTAAATATGTCAAGCTTTTTAGGCTTGTCACAAATGATTGCTTTGTTTTCCTAAGTCATCAAAATGTA
TATAAATTATCTAGATTGGATAACAGTCTTGCATGTTTATCATGTTACAATTTAATATTCCATCCTGCCCAACCCTTCCTCTCCCATCCT
CAAAAAAGGGCCATTTTATGATGCATTGCACACCCTCTGGGGAAATTGATCTTTAAATTTTGAGACAGTATAAGGAAAATCTGGTTGGTG
TCTTACAAGTGAGCTGACACCATTTTTTATTCTGTGTATTTAGAATGAAGTCTTGAAAAAAACTTTATAAAGACATCTTTAATCATTCCA
AAATTGTGTCCGTTTTCTTGAGCGTTTTGATTTTTTACTTTTAGCTTATACCAGCTGAATGGCAGCCTTGCCTAATCCACCTACAACAAG
AATTTCTTAAGCTTTCTTTTATTTGCATGAGAGAGCCACTACCAAGGCATGTTTTGTTATGCTGAAACTGGGCTGCTGCATACTGCTAAA
TGGCACCTCTGGGATTGGCCTACCTGGGGATTTCTTGGTTTGTGAAAACAGGAGAGGAGAAATATCTCATACAAGTGAAAGGATACTGGA
GAGAGAAATTACCCATTTCTAAAAAAAAACCACACTCTGTCGTATCTGTGTTAATGTTTTCTAGCATGTACTCTGGTTTCAACAGACACA
AATTTATATGTTAACCCAGTTTTCTTGCCGTTCTGTAAGTGTTTTATTCTTAGTGTGATTTTTTTCCATTGGGATGTTTTTGATTGAACT

>34656_34656_9_GRB2-VMP1_GRB2_chr17_73389632_ENST00000392564_VMP1_chr17_57842332_ENST00000262291_length(amino acids)=294AA_BP=24
MEAIAKYDFKATADDELSFKRGDILKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGE
LPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGAT
LIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILS

--------------------------------------------------------------
>34656_34656_10_GRB2-VMP1_GRB2_chr17_73389632_ENST00000392564_VMP1_chr17_57842332_ENST00000537567_length(transcript)=1381nt_BP=314nt
GAGCCAGGGGGCGTGGGGGCTGGGACAGCAGGCCGATTGGCAGGGCGGGGTTGCCTTCAATCCTGGCCACTGCTCTTAATCGTCCCTCTC
CTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAG
CAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTA
CTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATT
CAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCA
TCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCC
TCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGG
CCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGG
CTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCC
AGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTC
TGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGT
TGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAAC
GAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTT
AAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCC
ATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCACCCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGAAT

>34656_34656_10_GRB2-VMP1_GRB2_chr17_73389632_ENST00000392564_VMP1_chr17_57842332_ENST00000537567_length(amino acids)=294AA_BP=24
MEAIAKYDFKATADDELSFKRGDILKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGE
LPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGAT
LIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILS

--------------------------------------------------------------
>34656_34656_11_GRB2-VMP1_GRB2_chr17_73389632_ENST00000578961_VMP1_chr17_57842332_ENST00000262291_length(transcript)=2241nt_BP=253nt
CCTGGCCACTGCTCTTAATCGTCCCTCTCCTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAG
GCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGA
AGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGGTCCACATATAGCCTC
AGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCAC
TGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCC
TCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGC
AGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGC
TTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAAT
TGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCAT
TGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGA
AATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCAT
TAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAGTTTTAAACTG
CAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTATCAATTTTTA
CAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCACCCTCGATGCA
ATCCACCTTGTGTTTTCTTAGGGTGGAATGTGATGTTCAGCAGCAAACTTGCAACAGACTGGCCTTCTGTTTGTTACTTTCAAAAGGCCC
ACATGATACAATTAGAGAATTCCCACCGCACAAAAAAAGTTCCTAAGTATGTTAAATATGTCAAGCTTTTTAGGCTTGTCACAAATGATT
GCTTTGTTTTCCTAAGTCATCAAAATGTATATAAATTATCTAGATTGGATAACAGTCTTGCATGTTTATCATGTTACAATTTAATATTCC
ATCCTGCCCAACCCTTCCTCTCCCATCCTCAAAAAAGGGCCATTTTATGATGCATTGCACACCCTCTGGGGAAATTGATCTTTAAATTTT
GAGACAGTATAAGGAAAATCTGGTTGGTGTCTTACAAGTGAGCTGACACCATTTTTTATTCTGTGTATTTAGAATGAAGTCTTGAAAAAA
ACTTTATAAAGACATCTTTAATCATTCCAAAATTGTGTCCGTTTTCTTGAGCGTTTTGATTTTTTACTTTTAGCTTATACCAGCTGAATG
GCAGCCTTGCCTAATCCACCTACAACAAGAATTTCTTAAGCTTTCTTTTATTTGCATGAGAGAGCCACTACCAAGGCATGTTTTGTTATG
CTGAAACTGGGCTGCTGCATACTGCTAAATGGCACCTCTGGGATTGGCCTACCTGGGGATTTCTTGGTTTGTGAAAACAGGAGAGGAGAA
ATATCTCATACAAGTGAAAGGATACTGGAGAGAGAAATTACCCATTTCTAAAAAAAAACCACACTCTGTCGTATCTGTGTTAATGTTTTC
TAGCATGTACTCTGGTTTCAACAGACACAAATTTATATGTTAACCCAGTTTTCTTGCCGTTCTGTAAGTGTTTTATTCTTAGTGTGATTT

>34656_34656_11_GRB2-VMP1_GRB2_chr17_73389632_ENST00000578961_VMP1_chr17_57842332_ENST00000262291_length(amino acids)=294AA_BP=24
MEAIAKYDFKATADDELSFKRGDILKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGE
LPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGAT
LIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILS

--------------------------------------------------------------
>34656_34656_12_GRB2-VMP1_GRB2_chr17_73389632_ENST00000578961_VMP1_chr17_57842332_ENST00000537567_length(transcript)=1320nt_BP=253nt
CCTGGCCACTGCTCTTAATCGTCCCTCTCCTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAG
GCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGA
AGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGGTCCACATATAGCCTC
AGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCAC
TGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCC
TCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGC
AGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGC
TTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAAT
TGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCAT
TGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGA
AATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCAT
TAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAGTTTTAAACTG
CAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTATCAATTTTTA
CAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCACCCTCGATGCA

>34656_34656_12_GRB2-VMP1_GRB2_chr17_73389632_ENST00000578961_VMP1_chr17_57842332_ENST00000537567_length(amino acids)=294AA_BP=24
MEAIAKYDFKATADDELSFKRGDILKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGE
LPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGAT
LIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILS

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for GRB2-VMP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for GRB2-VMP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for GRB2-VMP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource