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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:GSN-HLA-F (FusionGDB2 ID:35072)

Fusion Gene Summary for GSN-HLA-F

Fusion gene summary

Fusion gene information	Fusion gene name: GSN-HLA-F
	Fusion gene ID: 35072
		Hgene	Tgene
	Gene symbol	GSN	HLA-F
	Gene ID	2934	3134
	Gene name	gelsolin	major histocompatibility complex, class I, F
	Synonyms	ADF\|AGEL	CDA12\|HLA-5.4\|HLA-CDA12\|HLAF
	Cytomap	9q33.2	6p22.1
	Type of gene	protein-coding	protein-coding
	Description	gelsolinactin-depolymerizing factorbrevinepididymis secretory sperm binding protein	HLA class I histocompatibility antigen, alpha chain FHLA F antigenMHC class I antigen Fleukocyte antigen F
	Modification date	20200329	20200313
	UniProtAcc	.	P30511
	Ensembl transtripts involved in fusion gene	ENST00000341272, ENST00000373808, ENST00000373818, ENST00000373823, ENST00000394353, ENST00000412819, ENST00000436847, ENST00000449733, ENST00000373806, ENST00000373807, ENST00000485767, ENST00000545652,	ENST00000259951, ENST00000334668, ENST00000376861, ENST00000440587, ENST00000342322, ENST00000359076, ENST00000376848, ENST00000383515, ENST00000383516, ENST00000383626, ENST00000383627, ENST00000420067, ENST00000422439, ENST00000422711, ENST00000428296, ENST00000430472, ENST00000434407, ENST00000435058, ENST00000440590, ENST00000444891, ENST00000445657, ENST00000463731, ENST00000475996, ENST00000485297, ENST00000489167, ENST00000490259, ENST00000490874, ENST00000496199, ENST00000547132, ENST00000549067, ENST00000549254, ENST00000549422, ENST00000550932, ENST00000551026, ENST00000551347, ENST00000551780, ENST00000551832, ENST00000552082, ENST00000552880,
Fusion gene scores	* DoF score	21 X 16 X 8=2688	2 X 2 X 2=8
	# samples	24	2
	** MAII score	log2(24/2688*10)=-3.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(2/8*10)=1.32192809488736
Context	PubMed: GSN [Title/Abstract] AND HLA-F [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	GSN(124095016)-HLA-F(29691219), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	GSN	GO:0030041	actin filament polymerization	3020431
Hgene	GSN	GO:0051014	actin filament severing	3020431
Tgene	HLA-F	GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	28636952
Tgene	HLA-F	GO:0002477	antigen processing and presentation of exogenous peptide antigen via MHC class Ib	23851683
Tgene	HLA-F	GO:0002725	negative regulation of T cell cytokine production	24018270
Tgene	HLA-F	GO:0002728	negative regulation of natural killer cell cytokine production	24018270
Tgene	HLA-F	GO:0002729	positive regulation of natural killer cell cytokine production	27455421
Tgene	HLA-F	GO:0043322	negative regulation of natural killer cell degranulation	24018270
Tgene	HLA-F	GO:0043323	positive regulation of natural killer cell degranulation	27455421
Tgene	HLA-F	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	24018270
Tgene	HLA-F	GO:1901215	negative regulation of neuron death	26928464

Fusion gene breakpoints across GSN (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across HLA-F (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LUAD	TCGA-78-7542-01A	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+

Top

Fusion Gene ORF analysis for GSN-HLA-F

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
3UTR-5UTR	ENST00000341272	ENST00000259951	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000341272	ENST00000334668	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000341272	ENST00000376861	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000341272	ENST00000440587	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000373808	ENST00000259951	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000373808	ENST00000334668	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000373808	ENST00000376861	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000373808	ENST00000440587	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000373818	ENST00000259951	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000373818	ENST00000334668	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000373818	ENST00000376861	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000373818	ENST00000440587	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000373823	ENST00000259951	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000373823	ENST00000334668	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000373823	ENST00000376861	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000373823	ENST00000440587	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000394353	ENST00000259951	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000394353	ENST00000334668	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000394353	ENST00000376861	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000394353	ENST00000440587	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000412819	ENST00000259951	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000412819	ENST00000334668	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000412819	ENST00000376861	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000412819	ENST00000440587	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000436847	ENST00000259951	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000436847	ENST00000334668	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000436847	ENST00000376861	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000436847	ENST00000440587	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000449733	ENST00000259951	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000449733	ENST00000334668	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000449733	ENST00000376861	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-5UTR	ENST00000449733	ENST00000440587	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000342322	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000359076	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000376848	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000383515	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000383516	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000383626	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000383627	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000420067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000422439	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000422711	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000428296	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000430472	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000434407	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000435058	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000440590	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000444891	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000445657	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000463731	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000475996	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000485297	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000489167	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000490259	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000490874	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000496199	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000547132	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000549067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000549254	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000549422	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000550932	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000551026	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000551347	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000551780	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000551832	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000552082	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000341272	ENST00000552880	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000342322	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000359076	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000376848	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000383515	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000383516	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000383626	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000383627	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000420067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000422439	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000422711	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000428296	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000430472	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000434407	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000435058	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000440590	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000444891	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000445657	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000463731	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000475996	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000485297	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000489167	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000490259	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000490874	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000496199	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000547132	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000549067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000549254	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000549422	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000550932	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000551026	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000551347	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000551780	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000551832	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000552082	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373808	ENST00000552880	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000342322	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000359076	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000376848	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000383515	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000383516	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000383626	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000383627	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000420067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000422439	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000422711	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000428296	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000430472	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000434407	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000435058	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000440590	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000444891	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000445657	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000463731	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000475996	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000485297	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000489167	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000490259	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000490874	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000496199	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000547132	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000549067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000549254	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000549422	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000550932	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000551026	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000551347	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000551780	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000551832	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000552082	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373818	ENST00000552880	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000342322	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000359076	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000376848	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000383515	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000383516	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000383626	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000383627	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000420067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000422439	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000422711	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000428296	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000430472	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000434407	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000435058	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000440590	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000444891	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000445657	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000463731	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000475996	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000485297	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000489167	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000490259	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000490874	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000496199	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000547132	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000549067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000549254	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000549422	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000550932	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000551026	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000551347	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000551780	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000551832	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000552082	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000373823	ENST00000552880	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000342322	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000359076	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000376848	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000383515	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000383516	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000383626	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000383627	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000420067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000422439	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000422711	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000428296	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000430472	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000434407	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000435058	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000440590	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000444891	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000445657	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000463731	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000475996	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000485297	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000489167	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000490259	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000490874	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000496199	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000547132	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000549067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000549254	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000549422	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000550932	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000551026	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000551347	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000551780	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000551832	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000552082	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000394353	ENST00000552880	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000342322	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000359076	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000376848	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000383515	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000383516	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000383626	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000383627	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000420067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000422439	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000422711	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000428296	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000430472	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000434407	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000435058	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000440590	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000444891	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000445657	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000463731	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000475996	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000485297	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000489167	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000490259	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000490874	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000496199	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000547132	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000549067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000549254	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000549422	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000550932	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000551026	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000551347	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000551780	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000551832	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000552082	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000412819	ENST00000552880	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000342322	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000359076	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000376848	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000383515	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000383516	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000383626	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000383627	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000420067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000422439	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000422711	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000428296	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000430472	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000434407	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000435058	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000440590	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000444891	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000445657	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000463731	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000475996	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000485297	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000489167	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000490259	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000490874	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000496199	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000547132	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000549067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000549254	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000549422	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000550932	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000551026	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000551347	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000551780	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000551832	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000552082	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000436847	ENST00000552880	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000342322	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000359076	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000376848	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000383515	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000383516	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000383626	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000383627	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000420067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000422439	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000422711	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000428296	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000430472	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000434407	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000435058	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000440590	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000444891	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000445657	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000463731	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000475996	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000485297	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000489167	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000490259	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000490874	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000496199	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000547132	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000549067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000549254	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000549422	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000550932	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000551026	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000551347	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000551780	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000551832	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000552082	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
3UTR-intron	ENST00000449733	ENST00000552880	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000373806	ENST00000259951	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000373806	ENST00000334668	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000373806	ENST00000376861	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000373806	ENST00000440587	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000373807	ENST00000259951	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000373807	ENST00000334668	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000373807	ENST00000376861	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000373807	ENST00000440587	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000485767	ENST00000259951	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000485767	ENST00000334668	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000485767	ENST00000376861	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000485767	ENST00000440587	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000545652	ENST00000259951	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000545652	ENST00000334668	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000545652	ENST00000376861	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-5UTR	ENST00000545652	ENST00000440587	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000342322	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000359076	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000376848	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000383515	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000383516	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000383626	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000383627	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000420067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000422439	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000422711	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000428296	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000430472	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000434407	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000435058	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000440590	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000444891	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000445657	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000463731	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000475996	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000485297	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000489167	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000490259	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000490874	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000496199	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000547132	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000549067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000549254	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000549422	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000550932	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000551026	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000551347	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000551780	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000551832	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000552082	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373806	ENST00000552880	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000342322	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000359076	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000376848	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000383515	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000383516	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000383626	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000383627	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000420067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000422439	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000422711	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000428296	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000430472	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000434407	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000435058	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000440590	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000444891	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000445657	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000463731	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000475996	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000485297	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000489167	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000490259	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000490874	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000496199	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000547132	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000549067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000549254	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000549422	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000550932	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000551026	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000551347	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000551780	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000551832	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000552082	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000373807	ENST00000552880	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000342322	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000359076	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000376848	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000383515	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000383516	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000383626	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000383627	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000420067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000422439	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000422711	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000428296	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000430472	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000434407	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000435058	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000440590	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000444891	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000445657	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000463731	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000475996	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000485297	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000489167	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000490259	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000490874	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000496199	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000547132	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000549067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000549254	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000549422	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000550932	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000551026	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000551347	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000551780	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000551832	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000552082	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000485767	ENST00000552880	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000342322	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000359076	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000376848	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000383515	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000383516	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000383626	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000383627	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000420067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000422439	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000422711	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000428296	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000430472	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000434407	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000435058	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000440590	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000444891	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000445657	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000463731	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000475996	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000485297	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000489167	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000490259	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000490874	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000496199	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000547132	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000549067	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000549254	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000549422	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000550932	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000551026	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000551347	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000551780	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000551832	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000552082	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+
intron-intron	ENST00000545652	ENST00000552880	GSN	chr9	124095016	-	HLA-F	chr6	29691219	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

No-coding score

Coding score

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Fusion Genomic Features for GSN-HLA-F

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GSN-HLA-F

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:124095016/:29691219)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	HLA-F P30511
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Non-classical major histocompatibility class Ib molecule postulated to play a role in immune surveillance, immune tolerance and inflammation. Functions in two forms, as a heterotrimeric complex with B2M/beta-2 microglobulin and a peptide (peptide-bound HLA-F-B2M) and as an open conformer (OC) devoid of peptide and B2M (peptide-free OC). In complex with B2M, presents non-canonical self-peptides carrying post-translational modifications, particularly phosphorylated self-peptides. Peptide-bound HLA-F-B2M acts as a ligand for LILRB1 inhibitory receptor, a major player in maternal-fetal tolerance. Peptide-free OC acts as a ligand for KIR3DS1 and KIR3DL2 receptors (PubMed:28636952). Upon interaction with activating KIR3DS1 receptor on NK cells, triggers NK cell degranulation and anti-viral cytokine production (PubMed:27455421). Through interaction with KIR3DL2 receptor, inhibits NK and T cell effector functions (PubMed:24018270). May interact with other MHC class I OCs to cross-present exogenous viral, tumor or minor histompatibility antigens to cytotoxic CD8+ T cells, triggering effector and memory responses (PubMed:23851683). May play a role in inflammatory responses in the peripheral nervous system. Through interaction with KIR3DL2, may protect motor neurons from astrocyte-induced toxicity (PubMed:26928464). {ECO:0000269\|PubMed:23851683, ECO:0000269\|PubMed:24018270, ECO:0000269\|PubMed:26928464, ECO:0000269\|PubMed:27455421, ECO:0000269\|PubMed:28636952}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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Fusion Gene Sequence for GSN-HLA-F

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for GSN-HLA-F

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for GSN-HLA-F

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for GSN-HLA-F

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source