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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
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Fusion gene:GTF2B-ODF2L (FusionGDB2 ID:35169)

Fusion Gene Summary for GTF2B-ODF2L

Fusion gene summary

Fusion gene information	Fusion gene name: GTF2B-ODF2L
	Fusion gene ID: 35169
		Hgene	Tgene
	Gene symbol	GTF2B	ODF2L
	Gene ID	2959	57489
	Gene name	general transcription factor IIB	outer dense fiber of sperm tails 2 like
	Synonyms	TF2B\|TFIIB	-
	Cytomap	1p22.2	1p22.3
	Type of gene	protein-coding	protein-coding
	Description	transcription initiation factor IIBRNA polymerase II transcription factor IIBS300-IIgeneral transcription factor TFIIB	protein BCAPbasal body centriole-associated protein
	Modification date	20200313	20200313
	UniProtAcc	Q00403	.
	Ensembl transtripts involved in fusion gene	ENST00000370500, ENST00000494819,	ENST00000524695, ENST00000478286, ENST00000486215, ENST00000294678, ENST00000317336, ENST00000359242, ENST00000370566, ENST00000370567, ENST00000394731,
Fusion gene scores	* DoF score	3 X 2 X 2=12	3 X 3 X 3=27
	# samples	3	3
	** MAII score	log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: GTF2B [Title/Abstract] AND ODF2L [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	GTF2B(89357166)-ODF2L(86826219), # samples:3
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	GTF2B	GO:0006366	transcription by RNA polymerase II	27193682
Hgene	GTF2B	GO:0006367	transcription initiation from RNA polymerase II promoter	3029109
Hgene	GTF2B	GO:0006473	protein acetylation	12931194
Hgene	GTF2B	GO:0043923	positive regulation by host of viral transcription	24441171
Hgene	GTF2B	GO:0051123	RNA polymerase II preinitiation complex assembly	3029109\|9841876
Hgene	GTF2B	GO:1904798	positive regulation of core promoter binding	9841876
Tgene	ODF2L	GO:1902018	negative regulation of cilium assembly	28775150

Fusion gene breakpoints across GTF2B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across ODF2L (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	PRAD	TCGA-Y6-A9XI-01A	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
ChimerDB4	PRAD	TCGA-Y6-A9XI	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-

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Fusion Gene ORF analysis for GTF2B-ODF2L

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000370500	ENST00000524695	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
5CDS-intron	ENST00000370500	ENST00000478286	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
5CDS-intron	ENST00000370500	ENST00000486215	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
5UTR-3CDS	ENST00000494819	ENST00000294678	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
5UTR-3CDS	ENST00000494819	ENST00000317336	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
5UTR-3CDS	ENST00000494819	ENST00000359242	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
5UTR-3CDS	ENST00000494819	ENST00000370566	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
5UTR-3CDS	ENST00000494819	ENST00000370567	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
5UTR-3CDS	ENST00000494819	ENST00000394731	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
5UTR-5UTR	ENST00000494819	ENST00000524695	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
5UTR-intron	ENST00000494819	ENST00000478286	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
5UTR-intron	ENST00000494819	ENST00000486215	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
In-frame	ENST00000370500	ENST00000294678	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
In-frame	ENST00000370500	ENST00000317336	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
In-frame	ENST00000370500	ENST00000359242	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
In-frame	ENST00000370500	ENST00000370566	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
In-frame	ENST00000370500	ENST00000370567	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-
In-frame	ENST00000370500	ENST00000394731	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000370500	GTF2B	chr1	89357166	-	ENST00000359242	ODF2L	chr1	86826219	-	4434	136	37	903	288
ENST00000370500	GTF2B	chr1	89357166	-	ENST00000370567	ODF2L	chr1	86826219	-	1027	136	37	1014	325
ENST00000370500	GTF2B	chr1	89357166	-	ENST00000394731	ODF2L	chr1	86826219	-	1027	136	37	1014	325
ENST00000370500	GTF2B	chr1	89357166	-	ENST00000317336	ODF2L	chr1	86826219	-	1027	136	37	1014	325
ENST00000370500	GTF2B	chr1	89357166	-	ENST00000370566	ODF2L	chr1	86826219	-	868	136	37	855	272
ENST00000370500	GTF2B	chr1	89357166	-	ENST00000294678	ODF2L	chr1	86826219	-	3040	136	37	942	301

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000370500	ENST00000359242	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-	0.005215663	0.9947843
ENST00000370500	ENST00000370567	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-	0.00812336	0.9918766
ENST00000370500	ENST00000394731	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-	0.00812336	0.9918766
ENST00000370500	ENST00000317336	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-	0.00812336	0.9918766
ENST00000370500	ENST00000370566	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-	0.00536986	0.9946301
ENST00000370500	ENST00000294678	GTF2B	chr1	89357166	-	ODF2L	chr1	86826219	-	0.020519296	0.97948074

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Fusion Genomic Features for GTF2B-ODF2L

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GTF2B-ODF2L

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:89357166/chr1:86826219)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
GTF2B Q00403	.
FUNCTION: General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA (PubMed:1876184, PubMed:1946368, PubMed:1517211, PubMed:3818643, PubMed:3029109, PubMed:8413225, PubMed:8515820, PubMed:8516311, PubMed:8516312, PubMed:7601352, PubMed:9420329, PubMed:12931194, PubMed:27193682). Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II-TFIIF complex (PubMed:8504927, PubMed:8413225, PubMed:8515820, PubMed:8516311, PubMed:8516312). Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle (PubMed:7601352). Associates with chromatin to core promoter-specific regions (PubMed:12931194, PubMed:24441171). Binds to two distinct DNA core promoter consensus sequence elements in a TBP-independent manner; these IIB-recognition elements (BREs) are localized immediately upstream (BREu), 5'-[GC][GC][GA]CGCC-3', and downstream (BREd), 5'-[GA]T[TGA][TG][GT][TG][TG]-3', of the TATA box element (PubMed:9420329, PubMed:16230532, PubMed:7675079, PubMed:10619841). Modulates transcription start site selection (PubMed:10318856). Exhibits also autoacetyltransferase activity that contributes to the activated transcription (PubMed:12931194). {ECO:0000269\|PubMed:10318856, ECO:0000269\|PubMed:10619841, ECO:0000269\|PubMed:12931194, ECO:0000269\|PubMed:1517211, ECO:0000269\|PubMed:16230532, ECO:0000269\|PubMed:1876184, ECO:0000269\|PubMed:1946368, ECO:0000269\|PubMed:24441171, ECO:0000269\|PubMed:27193682, ECO:0000269\|PubMed:3029109, ECO:0000269\|PubMed:3818643, ECO:0000269\|PubMed:7601352, ECO:0000269\|PubMed:7675079, ECO:0000269\|PubMed:8413225, ECO:0000269\|PubMed:8504927, ECO:0000269\|PubMed:8515820, ECO:0000269\|PubMed:8516311, ECO:0000269\|PubMed:8516312, ECO:0000269\|PubMed:9420329}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000294678

377_484

352

621.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000294678

519_631

352

621.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000359242

519_631

381

637.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000370566

377_484

352

592.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000370566

519_631

352

592.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000370567

377_484

352

645.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000370567

519_631

352

645.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000394731

249_325

221

514.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000394731

377_484

221

514.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000394731

519_631

221

514.0

Coiled coil

Ontology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

GTF2B

chr1:89357166

chr1:86826219

ENST00000370500

189_193

317.0

Region

Core promoter DNA-binding

Hgene

GTF2B

chr1:89357166

chr1:86826219

ENST00000370500

244_316

317.0

Region

Necessary for TATA box-bound TBP complex formation

Hgene

GTF2B

chr1:89357166

chr1:86826219

ENST00000370500

249_252

317.0

Region

Core promoter DNA-binding

Hgene

GTF2B

chr1:89357166

chr1:86826219

ENST00000370500

283_286

317.0

Region

Core promoter DNA-binding

Hgene

GTF2B

chr1:89357166

chr1:86826219

ENST00000370500

124_200

317.0

Repeat

Note=1

Hgene

GTF2B

chr1:89357166

chr1:86826219

ENST00000370500

218_294

317.0

Repeat

Note=2

Hgene

GTF2B

chr1:89357166

chr1:86826219

ENST00000370500

11_42

317.0

Zinc finger

TFIIB-type

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000294678

141_220

352

621.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000294678

249_325

352

621.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000294678

36_97

352

621.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000359242

141_220

381

637.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000359242

249_325

381

637.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000359242

36_97

381

637.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000359242

377_484

381

637.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000370566

141_220

352

592.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000370566

249_325

352

592.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000370566

36_97

352

592.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000370567

141_220

352

645.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000370567

249_325

352

645.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000370567

36_97

352

645.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000394731

141_220

221

514.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

ODF2L

chr1:89357166

chr1:86826219

ENST00000394731

36_97

221

514.0

Coiled coil

Ontology_term=ECO:0000255

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Fusion Gene Sequence for GTF2B-ODF2L

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>35169_35169_1_GTF2B-ODF2L_GTF2B_chr1_89357166_ENST00000370500_ODF2L_chr1_86826219_ENST00000294678_length(transcript)=3040nt_BP=136nt
ACGACTGCGTGGGTGAGTCGTCTATAAAAACTCATCTCTGCGCGTCTCTTCGCCACATTCGCTTCCTGCTTTCGGTGTGTCTGTTGTGTC
TTGTTGCGGGCACCGCAGTCGCCGTGAAGATGGCGTCTACCAGCCGACTACACTTGCTGCTTTGAAGGATGAAGTTGTATCTGTTGAAAA
TGAACTCTCAGAATTGCAAGAAGTAGAAAAAAAACAGAAAACCCTTATTGAAATGTATAAAACTCAGGTACAAAAGTTGCAAGAAGCAGC
TGAAATAGTAAAAAGCAGATGTGAAAATTTGCTACATAAAAATAACCAAATAACAAAAACCAAAAATAAAAATGTAGAGAAGATGAGAGG
CCAGATGGAGTCTCATCTGAAGGAGTTAGAGCGTGTCTGCGATTCCTTGACGGCGGCGGAACGGAGGCTTCACGAGTGTCAGGAGAGTCT
GCAGTGCTGCAAGGGGAAGTGTGCAGACCAGGAACACACCATTAGGGAGCTTCAGGGCCAGATTTTGAAGCAGTGGGAAGAATATTCTGT
CTTGGCATGGGTTGATGGAAATCACAATCTTCTGACAAAGCTTTCTCTGGAAGAGGAAAACTGTCTTATTCAGCTGAAGTGTGAAAACCT
TCAACAAAAATTAGAACAGATGGACGCAGAAAATAAAGAGCTTGAGAAGAAGCTGGCAAACCAAGAAGAATGTCTTAAGCACAGCAATCT
TAAGTTTAAAGAGAAATCTGCAGAGTATACAGCATTGGCCAGACAACTGGAAGCTGCTTTAGAAGAAGGAAGACAAAAGGTTGCTGAAGA
AATAGAGAAAATGTCATCTAGAGAGAGTGCTTTACAAATTAAAATATTAGATCTGGAAACTGAGCTTAGAAAGAAAAATGAAGAACAAAA
TCAACTTGTTTGCAAAATGAACAGTGATCCAGAGACTCCATGAAATCTATTTTTTTAATTCCCAAGTGTCTAAAAAGTTGAAAACCTAAA
AGATTCAAGAGTTAAATGATTTTTGGCATGCACAATTTGATTTTATTGCCATCAAAAGTTTCATGACAACTTAGTCAGAACAAAACGTCG
ATCACCTTTAATTTAGCACAGGCCTTCCATTTATTTCTAAACTTTTTTTTAACTCACCATTTGACTTTCTGATATTGTAAAATGTGTGTG
CTGTTTTTTTGTGTAATTGAAGCCTCTGAAAAAATAAATGAGGTGGGTTTTGCTGTAATGTCCCTAGTACTTGGCTAAAGCTAGTAAAAT
AAATAGATCCCATTCACAATTGCCACAAAGAGAATAAAATACCTAGGAATCCAAATTACAAGGAATGTGAAGGACCTCTTCAAGGAGAAC
TACAAACCACTGCTTAAGGAAATAAGAGAGGACACAAACAAATGGAAAACATTCCATGCTTATGAATAAGATGAAACAAGATCATGAAAA
TGGCTATACTCCCCAAAGTAATTTATAGATTCAGTGCTATCCCCATCAAGCTACCATTGACTTTCTTCACAGAATTAGAAAAAACTACTT
CAAATTTCATATGGAACCAAAAAAGAGCTCACATAACCAAGACAATCCTAAGCAAAAAGAACAAAGCTGTAGGCATCACGCTACCTGACT
TCAAACTATACTACAAGGCTACAGTAACCAAAATAGCATGGTACTGGTGCCAAAACAGATATATAGACCAATGGAACAGAACAGAGGCCT
CAGAAATAACTCCACACATCTACAACCATCTGCTGTTTGACATACCTGAGAAAAACAAGAAATGGGGAAAGGATTCCCTATTTAATAAAT
GGTGTTGGGAAAACTGGCTAGCCATATGCAGAAAACTGAAACTGGATCCCTTCCTTACACCTTATACAAAAATTAACTCAAGATGGATTA
AAGACTTAAGTGTAAGACCTAAAACCATAAAAACCCTAGAGGAAAACCTAGGCAATACCATTCAGGACATAGGCATGGACGAATACTTCA
TGACTAAAACACCAAAAGTAATGGCAATAAAAGCCAAGATTGACAAATGGGATCTAATTAAACTAAAGAGCTTCTGCACAGCAAAAGAAA
CTATCATCAGAGTGAACAGGAACCGACAGAATGGGAGAAAATTTTTGCAATCTATCCATCTGACAAAGGGCCAATATCCAGAATCTACAA
AGAACTTAAACAAATTTACAAGAAAAAAAACCCCATCAAAAAGTGTGCAAAGAATATGAACAGACACTTCTCAAGAGAAGACATTTAGTC
AGCCAAAAAACATATGAAAAAAAGCTCATCACTGGTCATTCAGAGAAATGCAAATCAAAACTACAGTGAGATACCATGTCACACCAATTA
GAATGGTGATCATTAAAAAGACAGGAAACAACAGATGCTGGAGAGGATGTGGAGAAATAGGATGCTTTTACACTGTTGGTGGGAGTGTAA
ATTAGTTCAACCACTGCGGAAGACAGTGTGGCGATTCCTCAAGGATCTAGAACCAGAAATACCATTTGACCCAGCAATCCCATTACTGGG
TATATACCCAAAGGACTATAAATCATGCTGCTATAGAGACACATGCACACGTATATTTATTGTGGCACTATTCACAATAGCAAAGACTTG
GAGCCAACCCAAATGCCCATCAATGATAGACTGAATAAAGAAAATGTGGCACATACACCATGGAATACTATGCAGCCATAAAAAAGGATG
AGTTCATGTCCTTTGCAGGGACATGGATGAAGCTGGAAACCATCATTCTCAGCAAACTAACACAAGAACAGAAAACCAAACACCGCATGT
TCTCACTCATAAGTGGGAGTTGAACAATGAGAATACATGGATACAGGGCAGGGAACATCACACACCAGGGCCTGTCAGGGCGTGGGGGGC
TAGGGGAGGGATAACATTAGAAATTCCTAATGTAGATGACGGGTTGATGAGTGCAGCAAACCACCATGGCACGTGTATACCTATGTAACC

>35169_35169_1_GTF2B-ODF2L_GTF2B_chr1_89357166_ENST00000370500_ODF2L_chr1_86826219_ENST00000294678_length(amino acids)=301AA_BP=33
MRVSSPHSLPAFGVSVVSCCGHRSRREDGVYQPTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLH
KNNQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAERRLHECQESLQCCKGKCADQEHTIRELQGQILKQWEEYSVLAWVDGNHNLLT
KLSLEEENCLIQLKCENLQQKLEQMDAENKELEKKLANQEECLKHSNLKFKEKSAEYTALARQLEAALEEGRQKVAEEIEKMSSRESALQ

--------------------------------------------------------------
>35169_35169_2_GTF2B-ODF2L_GTF2B_chr1_89357166_ENST00000370500_ODF2L_chr1_86826219_ENST00000317336_length(transcript)=1027nt_BP=136nt
ACGACTGCGTGGGTGAGTCGTCTATAAAAACTCATCTCTGCGCGTCTCTTCGCCACATTCGCTTCCTGCTTTCGGTGTGTCTGTTGTGTC
TTGTTGCGGGCACCGCAGTCGCCGTGAAGATGGCGTCTACCAGCCGACTACACTTGCTGCTTTGAAGGATGAAGTTGTATCTGTTGAAAA
TGAACTCTCAGAATTGCAAGAAGTAGAAAAAAAACAGAAAACCCTTATTGAAATGTATAAAACTCAGGTACAAAAGTTGCAAGAAGCAGC
TGAAATAGTAAAAAGCAGATGTGAAAATTTGCTACATAAAAATAACCAAATAACAAAAACCAAAAATAAAAATGTAGAGAAGATGAGAGG
CCAGATGGAGTCTCATCTGAAGGAGTTAGAGCGTGTCTGCGATTCCTTGACGGCGGCGGAACGGAGGCTTCACGAGTGTCAGGAGAGTCT
GCAGTGCTGCAAGGGGAAGTGTGCAGACCAGGAACACACCATTAGGGAGCTTCAGGGCCAGGTTGATGGAAATCACAATCTTCTGACAAA
GCTTTCTCTGGAAGAGGAAAACTGTCTTATTCAGCTGAAGTGTGAAAACCTTCAACAAAAATTAGAACAGATGGACGCAGAAAATAAAGA
GCTTGAGAAGAAGCTGGCAAACCAAGAAGAATGTCTTAAGCACAGCAATCTTAAGTTTAAAGAGAAATCTGCAGAGTATACAGCATTGGC
CAGACAACTGGAAGCTGCTTTAGAAGAAGGAAGACAAAAGGTTGCTGAAGAAATAGAGAAAATGTCATCTAGAGAGAGTGCTTTACAAAT
TAAAATATTAGATCTGGAAACTGAGCTTAGAAAGAAAAATGAAGAACAAAATCAACTTGTTTGCAAAATGAACAGTAAAGCACAACATCA
GGAAGTGTGTTTGAAAGAAGTACAAAATAGTCTTGAGAAGTCGGAAAATCAAAATGAGAGTATTAAGAATTATTTACAGTTTCTTAAAAC

>35169_35169_2_GTF2B-ODF2L_GTF2B_chr1_89357166_ENST00000370500_ODF2L_chr1_86826219_ENST00000317336_length(amino acids)=325AA_BP=33
MRVSSPHSLPAFGVSVVSCCGHRSRREDGVYQPTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLH
KNNQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAERRLHECQESLQCCKGKCADQEHTIRELQGQVDGNHNLLTKLSLEEENCLIQL
KCENLQQKLEQMDAENKELEKKLANQEECLKHSNLKFKEKSAEYTALARQLEAALEEGRQKVAEEIEKMSSRESALQIKILDLETELRKK

--------------------------------------------------------------
>35169_35169_3_GTF2B-ODF2L_GTF2B_chr1_89357166_ENST00000370500_ODF2L_chr1_86826219_ENST00000359242_length(transcript)=4434nt_BP=136nt
ACGACTGCGTGGGTGAGTCGTCTATAAAAACTCATCTCTGCGCGTCTCTTCGCCACATTCGCTTCCTGCTTTCGGTGTGTCTGTTGTGTC
TTGTTGCGGGCACCGCAGTCGCCGTGAAGATGGCGTCTACCAGCCGACTACACTTGCTGCTTTGAAGGATGAAGTTGTATCTGTTGAAAA
TGAACTCTCAGAATTGCAAGAAGTAGAAAAAAAACAGAAAACCCTTATTGAAATGTATAAAACTCAGGTACAAAAGTTGCAAGAAGCAGC
TGAAATAGTAAAAAGCAGATGTGAAAATTTGCTACATAAAAATAACCAAATAACAAAAACCAAAAATAAAAATGTAGAGAAGATGAGAGG
CCAGATGGAGTCTCATCTGAAGGAGTTAGAGCGTGTCTGCGATTCCTTGACGGCGGCGGAACGGAGGCTTCACGAGTGTCAGGAGAGTCT
GCAGTGCTGCAAGGGGAAGTGTGCAGACCAGGAACACACCATTAGGGAGCTTCAGGGCCAGGTTGATGGAAATCACAATCTTCTGACAAA
GCTTTCTCTGGAAGAGGAAAACTGTCTTATTCAGCTGAAGTGTGAAAACCTTCAACAAAAATTAGAACAGATGGACGCAGAAAATAAAGA
GCTTGAGAAGAAGCTGGCAAACCAAGAAGAATGTCTTAAGCACAGCAATCTTAAGTTTAAAGAGAAATCTGCAGAGTATACAGCATTGGC
CAGACAACTGGAAGCTGCTTTAGAAGAAGGAAGACAAAAGGTTGCTGAAGAAATAGAGAAAATGTCATCTAGAGAGAGTGCTTTACAAAT
TAAAATATTAGATCTGGAAACTGAGCTTAGAAAGAAAAATGAAGAACAAAATCAACTTGTTTGCAAAATGAACAGTGATCCAGAGACTCC
ATGAAATCTATTTTTTTAATTCCCAAGTGTCTAAAAAGTTGAAAACCTAAAAGATTCAAGAGTTAAATGATTTTTGGCATGCACAATTTG
ATTTTATTGCCATCAAAAGTTTCATGACAACTTAGTCAGAACAAAACGTCGATCACCTTTAATTTAGCACAGGCCTTCCATTTATTTCTA
AACTTTTTTTTAACTCACCATTTGACTTTCTGATATTGTAAAATGTGTGTGCTGTTTTTTTGTGTAATTGAAGCCTCTGAAAAAATAAAT
GAGGTGGGTTTTGCTGTAATGTCCCTAGTACTTGGCTAAAGCTAGTAAAATAAATAGATCCCATTCACAATTGCCACAAAGAGAATAAAA
TACCTAGGAATCCAAATTACAAGGAATGTGAAGGACCTCTTCAAGGAGAACTACAAACCACTGCTTAAGGAAATAAGAGAGGACACAAAC
AAATGGAAAACATTCCATGCTTATGAATAAGATGAAACAAGATCATGAAAATGGCTATACTCCCCAAAGTAATTTATAGATTCAGTGCTA
TCCCCATCAAGCTACCATTGACTTTCTTCACAGAATTAGAAAAAACTACTTCAAATTTCATATGGAACCAAAAAAGAGCTCACATAACCA
AGACAATCCTAAGCAAAAAGAACAAAGCTGTAGGCATCACGCTACCTGACTTCAAACTATACTACAAGGCTACAGTAACCAAAATAGCAT
GGTACTGGTGCCAAAACAGATATATAGACCAATGGAACAGAACAGAGGCCTCAGAAATAACTCCACACATCTACAACCATCTGCTGTTTG
ACATACCTGAGAAAAACAAGAAATGGGGAAAGGATTCCCTATTTAATAAATGGTGTTGGGAAAACTGGCTAGCCATATGCAGAAAACTGA
AACTGGATCCCTTCCTTACACCTTATACAAAAATTAACTCAAGATGGATTAAAGACTTAAGTGTAAGACCTAAAACCATAAAAACCCTAG
AGGAAAACCTAGGCAATACCATTCAGGACATAGGCATGGACGAATACTTCATGACTAAAACACCAAAAGTAATGGCAATAAAAGCCAAGA
TTGACAAATGGGATCTAATTAAACTAAAGAGCTTCTGCACAGCAAAAGAAACTATCATCAGAGTGAACAGGAACCGACAGAATGGGAGAA
AATTTTTGCAATCTATCCATCTGACAAAGGGCCAATATCCAGAATCTACAAAGAACTTAAACAAATTTACAAGAAAAAAAACCCCATCAA
AAAGTGTGCAAAGAATATGAACAGACACTTCTCAAGAGAAGACATTTAGTCAGCCAAAAAACATATGAAAAAAAGCTCATCACTGGTCAT
TCAGAGAAATGCAAATCAAAACTACAGTGAGATACCATGTCACACCAATTAGAATGGTGATCATTAAAAAGACAGGAAACAACAGATGCT
GGAGAGGATGTGGAGAAATAGGATGCTTTTACACTGTTGGTGGGAGTGTAAATTAGTTCAACCACTGCGGAAGACAGTGTGGCGATTCCT
CAAGGATCTAGAACCAGAAATACCATTTGACCCAGCAATCCCATTACTGGGTATATACCCAAAGGACTATAAATCATGCTGCTATAGAGA
CACATGCACACGTATATTTATTGTGGCACTATTCACAATAGCAAAGACTTGGAGCCAACCCAAATGCCCATCAATGATAGACTGAATAAA
GAAAATGTGGCACATACACCATGGAATACTATGCAGCCATAAAAAAGGATGAGTTCATGTCCTTTGCAGGGACATGGATGAAGCTGGAAA
CCATCATTCTCAGCAAACTAACACAAGAACAGAAAACCAAACACCGCATGTTCTCACTCATAAGTGGGAGTTGAACAATGAGAATACATG
GATACAGGGCAGGGAACATCACACACCAGGGCCTGTCAGGGCGTGGGGGGCTAGGGGAGGGATAACATTAGAAATTCCTAATGTAGATGA
CGGGTTGATGAGTGCAGCAAACCACCATGGCACGTGTATACCTATGTAACCAACCTGTACGTTCTGTACATGTATCCCAGAACTTAAAGT
ATAATAAAAATTAAAAAAAATAAAGATCTGATGTTTTGTTAAACCTGATAAGTTTTGTACTAGTAAAATTCTAGAATTCTAAGCATAGAT
TTAAACATTGCTGAAAAATGAGTTTGTGTGTTTTATGCCTTCCAGGGGACAGTTAAGTGGGCAGTATTTATTTAATATACCTGCTTCAGC
CCCATTTGAATTGTAAGCACTCTGAAAGCATGTCTCATAGTCGTCTGTATCCCTGGTGTCTCCCACAGTGCCCTGCTTACCTGCAGGCCT
TTTTGTATTTTCTGTCCAAGTACCCTAATAGGGTGGTGCAGAATGGATGTACAGATCTGTGGATGACCTCAGCAGCTTAATCCAAGGCAC
CCCTCGGGAAGCCTGAAATGTCTTTGAAGTCTTATGTATTATCCTAAAATCCATTGACATTTTATATTCTACCCTACAAAATAAGTATGT
GTTACTATTTTTCTTTCCAAATTGTTGAGTAAAACTCATTGTATTCATCCTGTGACTTTGTACTGCCCAGCCTAGCTCATTGTTTTTTAC
CTGCCTCATTTCCTGAGCTGGGCATTGCTCAGTTTCAGAAGGTATCAGGTGTCATTGAACACCTGATATGAAGGATGTAAAAGTTCTCTC
TTTTCTATCTAGGTGTCTATATTTTAATTGGAGGCTAGATGATATTTGCAACCTGTCTTTATCTAAAGCATTGTCAGTGAACTCACCTAC
TTAGGAATTCATATGCACCTTAGTTAAAAAAAATGTATTGTGGTTTTAAATTTTTTCCTCAACCAGTGTAATATGAAGAATTCTTTTTAT
TTTTTAAGAGATTCTAAGAAAATGTTCACATTATCAAAACTAGAATTCTATCAACTTTTAAGACATTTAATTATTTTGGAATAAAATGTG
AATTTTTAGACAGAAAATGGCAAAAACTAGTATGAAAATATATCATGTTACATGTGAAATTATGACAGTTGTTAACCTATTAAGTTAATC
ATGTTAAATATGTAATAATTTGGGGCTAAATGAATGTATATTATAAATTATATCAGTGAAGATCAACCATGTGTGTGCTTTAATTATTAA
TTTTAAAGAGTGAGCTCTAAGAATGAACACATCAGATGTGAGTATTATTTTAAAAAATCAAAAAGAATTATCTAGTTATTGTATATATGT
TTTTAATATTATGACTCTGGTCCTTTGGAATGAATGCTATTATTGCTTATCTGTATTTTTTTCCTTTTTTCTTTAGAAAGCACAACATCA
GGAAGTGTGTTTGAAAGAAGTACAAAATAGTCTTGAGAAGTCGGAAAATCAAAATGAGAGTATTAAGAATTATTTACAGTTTCTTAAAAC
TTCTTATGTAACAATGTTTGAATAAATTGTCAAATTTATTTTCTCTAAGTAGTAGATTTTTATTATGAGTCTAAAATGTGATTGGGTAAA

>35169_35169_3_GTF2B-ODF2L_GTF2B_chr1_89357166_ENST00000370500_ODF2L_chr1_86826219_ENST00000359242_length(amino acids)=288AA_BP=33
MRVSSPHSLPAFGVSVVSCCGHRSRREDGVYQPTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLH
KNNQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAERRLHECQESLQCCKGKCADQEHTIRELQGQVDGNHNLLTKLSLEEENCLIQL
KCENLQQKLEQMDAENKELEKKLANQEECLKHSNLKFKEKSAEYTALARQLEAALEEGRQKVAEEIEKMSSRESALQIKILDLETELRKK

--------------------------------------------------------------
>35169_35169_4_GTF2B-ODF2L_GTF2B_chr1_89357166_ENST00000370500_ODF2L_chr1_86826219_ENST00000370566_length(transcript)=868nt_BP=136nt
ACGACTGCGTGGGTGAGTCGTCTATAAAAACTCATCTCTGCGCGTCTCTTCGCCACATTCGCTTCCTGCTTTCGGTGTGTCTGTTGTGTC
TTGTTGCGGGCACCGCAGTCGCCGTGAAGATGGCGTCTACCAGCCGACTACACTTGCTGCTTTGAAGGATGAAGTTGTATCTGTTGAAAA
TGAACTCTCAGAATTGCAAGAAGTAGAAAAAAAACAGAAAACCCTTATTGAAATGTATAAAACTCAGGTACAAAAGTTGCAAGAAGCAGC
TGAAATAGTAAAAAGCAGATGTGAAAATTTGCTACATAAAAATAACCAAATAACAAAAACCAAAAATAAAAATGTAGAGAAGGTTGATGG
AAATCACAATCTTCTGACAAAGCTTTCTCTGGAAGAGGAAAACTGTCTTATTCAGCTGAAGTGTGAAAACCTTCAACAAAAATTAGAACA
GATGGACGCAGAAAATAAAGAGCTTGAGAAGAAGCTGGCAAACCAAGAAGAATGTCTTAAGCACAGCAATCTTAAGTTTAAAGAGAAATC
TGCAGAGTATACAGCATTGGCCAGACAACTGGAAGCTGCTTTAGAAGAAGGAAGACAAAAGGTTGCTGAAGAAATAGAGAAAATGTCATC
TAGAGAGAGTGCTTTACAAATTAAAATATTAGATCTGGAAACTGAGCTTAGAAAGAAAAATGAAGAACAAAATCAACTTGTTTGCAAAAT
GAACAGTAAAGCACAACATCAGGAAGTGTGTTTGAAAGAAGTACAAAATAGTCTTGAGAAGTCGGAAAATCAAAATGAGAGTATTAAGAA

>35169_35169_4_GTF2B-ODF2L_GTF2B_chr1_89357166_ENST00000370500_ODF2L_chr1_86826219_ENST00000370566_length(amino acids)=272AA_BP=33
MRVSSPHSLPAFGVSVVSCCGHRSRREDGVYQPTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLH
KNNQITKTKNKNVEKVDGNHNLLTKLSLEEENCLIQLKCENLQQKLEQMDAENKELEKKLANQEECLKHSNLKFKEKSAEYTALARQLEA
ALEEGRQKVAEEIEKMSSRESALQIKILDLETELRKKNEEQNQLVCKMNSKAQHQEVCLKEVQNSLEKSENQNESIKNYLQFLKTSYVTM

--------------------------------------------------------------
>35169_35169_5_GTF2B-ODF2L_GTF2B_chr1_89357166_ENST00000370500_ODF2L_chr1_86826219_ENST00000370567_length(transcript)=1027nt_BP=136nt
ACGACTGCGTGGGTGAGTCGTCTATAAAAACTCATCTCTGCGCGTCTCTTCGCCACATTCGCTTCCTGCTTTCGGTGTGTCTGTTGTGTC
TTGTTGCGGGCACCGCAGTCGCCGTGAAGATGGCGTCTACCAGCCGACTACACTTGCTGCTTTGAAGGATGAAGTTGTATCTGTTGAAAA
TGAACTCTCAGAATTGCAAGAAGTAGAAAAAAAACAGAAAACCCTTATTGAAATGTATAAAACTCAGGTACAAAAGTTGCAAGAAGCAGC
TGAAATAGTAAAAAGCAGATGTGAAAATTTGCTACATAAAAATAACCAAATAACAAAAACCAAAAATAAAAATGTAGAGAAGATGAGAGG
CCAGATGGAGTCTCATCTGAAGGAGTTAGAGCGTGTCTGCGATTCCTTGACGGCGGCGGAACGGAGGCTTCACGAGTGTCAGGAGAGTCT
GCAGTGCTGCAAGGGGAAGTGTGCAGACCAGGAACACACCATTAGGGAGCTTCAGGGCCAGGTTGATGGAAATCACAATCTTCTGACAAA
GCTTTCTCTGGAAGAGGAAAACTGTCTTATTCAGCTGAAGTGTGAAAACCTTCAACAAAAATTAGAACAGATGGACGCAGAAAATAAAGA
GCTTGAGAAGAAGCTGGCAAACCAAGAAGAATGTCTTAAGCACAGCAATCTTAAGTTTAAAGAGAAATCTGCAGAGTATACAGCATTGGC
CAGACAACTGGAAGCTGCTTTAGAAGAAGGAAGACAAAAGGTTGCTGAAGAAATAGAGAAAATGTCATCTAGAGAGAGTGCTTTACAAAT
TAAAATATTAGATCTGGAAACTGAGCTTAGAAAGAAAAATGAAGAACAAAATCAACTTGTTTGCAAAATGAACAGTAAAGCACAACATCA
GGAAGTGTGTTTGAAAGAAGTACAAAATAGTCTTGAGAAGTCGGAAAATCAAAATGAGAGTATTAAGAATTATTTACAGTTTCTTAAAAC

>35169_35169_5_GTF2B-ODF2L_GTF2B_chr1_89357166_ENST00000370500_ODF2L_chr1_86826219_ENST00000370567_length(amino acids)=325AA_BP=33
MRVSSPHSLPAFGVSVVSCCGHRSRREDGVYQPTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLH
KNNQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAERRLHECQESLQCCKGKCADQEHTIRELQGQVDGNHNLLTKLSLEEENCLIQL
KCENLQQKLEQMDAENKELEKKLANQEECLKHSNLKFKEKSAEYTALARQLEAALEEGRQKVAEEIEKMSSRESALQIKILDLETELRKK

--------------------------------------------------------------
>35169_35169_6_GTF2B-ODF2L_GTF2B_chr1_89357166_ENST00000370500_ODF2L_chr1_86826219_ENST00000394731_length(transcript)=1027nt_BP=136nt
ACGACTGCGTGGGTGAGTCGTCTATAAAAACTCATCTCTGCGCGTCTCTTCGCCACATTCGCTTCCTGCTTTCGGTGTGTCTGTTGTGTC
TTGTTGCGGGCACCGCAGTCGCCGTGAAGATGGCGTCTACCAGCCGACTACACTTGCTGCTTTGAAGGATGAAGTTGTATCTGTTGAAAA
TGAACTCTCAGAATTGCAAGAAGTAGAAAAAAAACAGAAAACCCTTATTGAAATGTATAAAACTCAGGTACAAAAGTTGCAAGAAGCAGC
TGAAATAGTAAAAAGCAGATGTGAAAATTTGCTACATAAAAATAACCAAATAACAAAAACCAAAAATAAAAATGTAGAGAAGATGAGAGG
CCAGATGGAGTCTCATCTGAAGGAGTTAGAGCGTGTCTGCGATTCCTTGACGGCGGCGGAACGGAGGCTTCACGAGTGTCAGGAGAGTCT
GCAGTGCTGCAAGGGGAAGTGTGCAGACCAGGAACACACCATTAGGGAGCTTCAGGGCCAGGTTGATGGAAATCACAATCTTCTGACAAA
GCTTTCTCTGGAAGAGGAAAACTGTCTTATTCAGCTGAAGTGTGAAAACCTTCAACAAAAATTAGAACAGATGGACGCAGAAAATAAAGA
GCTTGAGAAGAAGCTGGCAAACCAAGAAGAATGTCTTAAGCACAGCAATCTTAAGTTTAAAGAGAAATCTGCAGAGTATACAGCATTGGC
CAGACAACTGGAAGCTGCTTTAGAAGAAGGAAGACAAAAGGTTGCTGAAGAAATAGAGAAAATGTCATCTAGAGAGAGTGCTTTACAAAT
TAAAATATTAGATCTGGAAACTGAGCTTAGAAAGAAAAATGAAGAACAAAATCAACTTGTTTGCAAAATGAACAGTAAAGCACAACATCA
GGAAGTGTGTTTGAAAGAAGTACAAAATAGTCTTGAGAAGTCGGAAAATCAAAATGAGAGTATTAAGAATTATTTACAGTTTCTTAAAAC

>35169_35169_6_GTF2B-ODF2L_GTF2B_chr1_89357166_ENST00000370500_ODF2L_chr1_86826219_ENST00000394731_length(amino acids)=325AA_BP=33
MRVSSPHSLPAFGVSVVSCCGHRSRREDGVYQPTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLH
KNNQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAERRLHECQESLQCCKGKCADQEHTIRELQGQVDGNHNLLTKLSLEEENCLIQL
KCENLQQKLEQMDAENKELEKKLANQEECLKHSNLKFKEKSAEYTALARQLEAALEEGRQKVAEEIEKMSSRESALQIKILDLETELRKK

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for GTF2B-ODF2L

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for GTF2B-ODF2L

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for GTF2B-ODF2L

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source