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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GTF2F2-RSF1 (FusionGDB2 ID:35197)

Fusion Gene Summary for GTF2F2-RSF1

check button Fusion gene summary
Fusion gene informationFusion gene name: GTF2F2-RSF1
Fusion gene ID: 35197
HgeneTgene
Gene symbol

GTF2F2

RSF1

Gene ID

2963

51773

Gene namegeneral transcription factor IIF subunit 2remodeling and spacing factor 1
SynonymsBTF4|RAP30|TF2F2|TFIIFHBXAP|RSF-1|XAP8|p325
Cytomap

13q14.12-q14.13

11q14.1

Type of geneprotein-codingprotein-coding
Descriptiongeneral transcription factor IIF subunit 2ATP-dependent helicase GTF2F2TFIIF-betageneral transcription factor IIF 30 kDa subunitgeneral transcription factor IIF, polypeptide 2, 30kDatranscription initiation factor IIF subunit betatranscription initiremodeling and spacing factor 1HBV pX-associated protein 8hepatitis B virus x-associated proteinp325 subunit of RSF chromatin-remodeling complex
Modification date2020031320200313
UniProtAcc

P13984

.
Ensembl transtripts involved in fusion geneENST00000340473, ENST00000494087, 
ENST00000480887, ENST00000530604, 
ENST00000308488, ENST00000360355, 
Fusion gene scores* DoF score11 X 7 X 7=53916 X 11 X 7=1232
# samples 1319
** MAII scorelog2(13/539*10)=-2.05177364972405
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/1232*10)=-2.69693093236395
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GTF2F2 [Title/Abstract] AND RSF1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGTF2F2(45725966)-RSF1(77413540), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneRSF1

GO:0006334

nucleosome assembly

12972596

TgeneRSF1

GO:0006338

chromatin remodeling

9836642

TgeneRSF1

GO:0006352

DNA-templated transcription, initiation

9836642

TgeneRSF1

GO:0016584

nucleosome positioning

9836642

TgeneRSF1

GO:0043392

negative regulation of DNA binding

12972596

TgeneRSF1

GO:0045892

negative regulation of transcription, DNA-templated

11944984

TgeneRSF1

GO:0045893

positive regulation of transcription, DNA-templated

11788598

TgeneRSF1

GO:0050434

positive regulation of viral transcription

11788598


check buttonFusion gene breakpoints across GTF2F2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RSF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-56-A4BX-01AGTF2F2chr13

45725966

-RSF1chr11

77413540

-
ChimerDB4LUSCTCGA-56-A4BX-01AGTF2F2chr13

45725966

+RSF1chr11

77413540

-


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Fusion Gene ORF analysis for GTF2F2-RSF1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000340473ENST00000480887GTF2F2chr13

45725966

+RSF1chr11

77413540

-
5CDS-intronENST00000340473ENST00000530604GTF2F2chr13

45725966

+RSF1chr11

77413540

-
In-frameENST00000340473ENST00000308488GTF2F2chr13

45725966

+RSF1chr11

77413540

-
In-frameENST00000340473ENST00000360355GTF2F2chr13

45725966

+RSF1chr11

77413540

-
intron-3CDSENST00000494087ENST00000308488GTF2F2chr13

45725966

+RSF1chr11

77413540

-
intron-3CDSENST00000494087ENST00000360355GTF2F2chr13

45725966

+RSF1chr11

77413540

-
intron-5UTRENST00000494087ENST00000480887GTF2F2chr13

45725966

+RSF1chr11

77413540

-
intron-intronENST00000494087ENST00000530604GTF2F2chr13

45725966

+RSF1chr11

77413540

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000340473GTF2F2chr1345725966+ENST00000308488RSF1chr1177413540-109594456040371325
ENST00000340473GTF2F2chr1345725966+ENST00000360355RSF1chr1177413540-47254456040371325

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000340473ENST00000308488GTF2F2chr1345725966+RSF1chr1177413540-0.0001669180.9998331
ENST00000340473ENST00000360355GTF2F2chr1345725966+RSF1chr1177413540-0.0009844160.99901557

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Fusion Genomic Features for GTF2F2-RSF1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GTF2F2-RSF1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:45725966/chr11:77413540)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GTF2F2

P13984

.
FUNCTION: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. {ECO:0000269|PubMed:2477704}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGTF2F2chr13:45725966chr11:77413540ENST00000340473+4836_43101250.0Nucleotide bindingATP
TgeneRSF1chr13:45725966chr11:77413540ENST00000308488416942_10122441442.0Coiled coilOntology_term=ECO:0000255
TgeneRSF1chr13:45725966chr11:77413540ENST00000360355315942_10122131411.0Coiled coilOntology_term=ECO:0000255
TgeneRSF1chr13:45725966chr11:77413540ENST00000480887011942_101201190.0Coiled coilOntology_term=ECO:0000255
TgeneRSF1chr13:45725966chr11:77413540ENST000003084884161080_10832441442.0Compositional biasNote=Poly-Ala
TgeneRSF1chr13:45725966chr11:77413540ENST000003084884161146_12432441442.0Compositional biasNote=Arg-rich
TgeneRSF1chr13:45725966chr11:77413540ENST000003084884161286_12922441442.0Compositional biasNote=Poly-Glu
TgeneRSF1chr13:45725966chr11:77413540ENST000003084884161419_14242441442.0Compositional biasNote=Poly-Glu
TgeneRSF1chr13:45725966chr11:77413540ENST00000308488416875_8842441442.0Compositional biasNote=Poly-Glu
TgeneRSF1chr13:45725966chr11:77413540ENST000003603553151080_10832131411.0Compositional biasNote=Poly-Ala
TgeneRSF1chr13:45725966chr11:77413540ENST000003603553151146_12432131411.0Compositional biasNote=Arg-rich
TgeneRSF1chr13:45725966chr11:77413540ENST000003603553151286_12922131411.0Compositional biasNote=Poly-Glu
TgeneRSF1chr13:45725966chr11:77413540ENST000003603553151419_14242131411.0Compositional biasNote=Poly-Glu
TgeneRSF1chr13:45725966chr11:77413540ENST00000360355315226_3722131411.0Compositional biasNote=Glu-rich
TgeneRSF1chr13:45725966chr11:77413540ENST00000360355315875_8842131411.0Compositional biasNote=Poly-Glu
TgeneRSF1chr13:45725966chr11:77413540ENST000004808870111080_108301190.0Compositional biasNote=Poly-Ala
TgeneRSF1chr13:45725966chr11:77413540ENST000004808870111146_124301190.0Compositional biasNote=Arg-rich
TgeneRSF1chr13:45725966chr11:77413540ENST000004808870111286_129201190.0Compositional biasNote=Poly-Glu
TgeneRSF1chr13:45725966chr11:77413540ENST000004808870111419_142401190.0Compositional biasNote=Poly-Glu
TgeneRSF1chr13:45725966chr11:77413540ENST00000480887011226_37201190.0Compositional biasNote=Glu-rich
TgeneRSF1chr13:45725966chr11:77413540ENST00000480887011875_88401190.0Compositional biasNote=Poly-Glu
TgeneRSF1chr13:45725966chr11:77413540ENST0000048088701117_8401190.0DomainNote=DDT
TgeneRSF1chr13:45725966chr11:77413540ENST00000308488416891_9412441442.0Zinc fingerPHD-type
TgeneRSF1chr13:45725966chr11:77413540ENST00000360355315891_9412131411.0Zinc fingerPHD-type
TgeneRSF1chr13:45725966chr11:77413540ENST00000480887011891_94101190.0Zinc fingerPHD-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRSF1chr13:45725966chr11:77413540ENST00000308488416226_3722441442.0Compositional biasNote=Glu-rich
TgeneRSF1chr13:45725966chr11:77413540ENST0000030848841617_842441442.0DomainNote=DDT
TgeneRSF1chr13:45725966chr11:77413540ENST0000036035531517_842131411.0DomainNote=DDT


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Fusion Gene Sequence for GTF2F2-RSF1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>35197_35197_1_GTF2F2-RSF1_GTF2F2_chr13_45725966_ENST00000340473_RSF1_chr11_77413540_ENST00000308488_length(transcript)=10959nt_BP=445nt
TTCCCAGTGTTCTGGCAGGTAAGGAACGCCGGCTCTTCGCCTCTCAGCGCGGCTTGTCCTTTGTTCCGGACGCCCGCTCCTCAGCCCTGC
GGCTCCTGGGGTCGCTGCTGCATCCCGCACGCCTCCACCGGCTGCAGACCCATGGCCGAGCGCGGGGAACTCGACTTGACCGGCGCCAAA
CAGAACACAGGAGTGTGGCTAGTCAAGGTTCCTAAATATTTGTCACAGCAATGGGCTAAAGCCTCTGGAAGAGGTGAAGTTGGGAAACTG
CGGATTGCCAAGACTCAAGGAAGGACTGAGGTGTCATTTACTTTGAATGAGGATCTTGCAAATATTCATGATATTGGTGGAAAACCAGCT
TCAGTCAGTGCTCCTAGAGAACATCCATTTGTCTTGCAAAGTGTTGGAGGACAGACATTAACAGTATTTACTGAGAGCTCATCAGAGGAA
CAGAAAGAAAGTGAAAAGATGAAAAGTGAGGAGCAGCCTATGGATTTAGAAAACCGTTCTACAGCCAATGTTCTAGAAGAGACTACTGTG
AAAAAAGAAAAAGAAGATGAAAAGGAACTTGTGAAACTGCCAGTCATAGTGAAGCTAGAAAAACCTTTGCCAGAAAATGAAGAAAAAAAG
ATTATCAAAGAAGAAAGTGATTCCTTCAAGGAAAATGTCAAACCCATTAAAGTTGAGGTGAAGGAATGTAGAGCAGATCCTAAAGATACC
AAAAGTAGCATGGAGAAGCCAGTGGCACAGGAGCCTGAAAGGATCGAATTTGGTGGCAATATTAAATCTTCTCACGAAATTACTGAGAAA
TCTACTGAAGAAACTGAGAAACTTAAAAATGACCAGCAGGCCAAGATACCACTAAAAAAACGAGAAATTAAACTGAGTGATGATTTTGAC
AGTCCAGTCAAGGGACCTTTGTGTAAATCAGTTACTCCAACAAAAGAGTTTTTGAAAGATGAAATAAAACAAGAGGAAGAGACTTGTAAA
AGGATCTCTACAATCACTGCTTTGGGTCATGAAGGGAAACAGCTGGTAAATGGAGAAGTTAGTGATGAAAGGGTAGCTCCAAATTTTAAG
ACAGAACCAATAGAGACAAAGTTTTATGAGACAAAGGAAGAGAGCTATAGCCCCTCTAAGGACAGAAATATCATCACGGAGGGAAATGGA
ACAGAGTCCTTAAATTCTGTCATAACAAGTATGAAAACAGGTGAGCTTGAGAAAGAAACAGCCCCTTTGAGGAAAGATGCAGATAGTTCA
ATATCAGTCTTAGAGATCCATAGTCAAAAAGCACAAATAGAGGAACCCGATCCTCCAGAAATGGAAACTTCTCTTGATTCTTCTGAGATG
GCAAAAGATCTCTCTTCAAAAACTGCTTTATCTTCCACCGAGTCGTGTACCATGAAAGGTGAAGAGAAGTCTCCCAAAACTAAGAAGGAT
AAGCGCCCACCAATCCTAGAATGTCTTGAAAAGTTAGAGAAGTCCAAAAAGACTTTTCTTGATAAGGACGCACAAAGATTGAGTCCAATA
CCAGAAGAAGTTCCAAAGAGTACTCTAGAGTCAGAAAAGCCTGGCTCTCCTGAGGCAGCTGAAACTTCTCCACCATCTAATATCATTGAC
CACTGTGAGAAACTAGCCTCAGAAAAAGAAGTGGTAGAATGCCAGAGTACAAGTACTGTTGGTGGCCAGTCTGTGAAAAAAGTAGACCTA
GAAACCCTAAAAGAGGATTCTGAGTTCACAAAGGTAGAAATGGATAATCTGGACAATGCCCAGACCTCTGGCATAGAGGAGCCTTCTGAG
ACAAAGGGTTCTATGCAAAAAAGCAAATTCAAATATAAGTTGGTTCCTGAAGAAGAAACCACTGCCTCAGAAAATACAGAGATAACCTCT
GAAAGGCAGAAAGAGGGCATCAAATTAACAATCAGGATATCAAGTCGGAAAAAGAAGCCCGATTCTCCCCCCAAAGTTCTAGAACCAGAA
AACAAGCAAGAGAAGACAGAAAAGGAAGAGGAGAAAACAAATGTGGGTCGTACTTTAAGAAGATCTCCAAGAATATCTAGACCCACTGCA
AAAGTGGCTGAGATCAGAGATCAGAAAGCTGATAAAAAAAGAGGGGAAGGAGAAGATGAGGTGGAAGAAGAGTCAACAGCTTTGCAAAAA
ACTGACAAAAAGGAAATTTTGAAAAAATCAGAGAAAGATACAAATTCTAAAGTAAGCAAGGTAAAACCCAAAGGCAAAGTTCGATGGACT
GGTTCTCGGACACGTGGCAGATGGAAATATTCCAGCAATGATGAAAGTGAAGGGTCTGGCAGTGAAAAATCATCTGCAGCTTCAGAAGAG
GAGGAAGAAAAGGAAAGTGAAGAAGCCATCCTAGCAGATGATGATGAACCATGCAAAAAATGTGGCCTTCCAAACCATCCTGAGCTAATT
CTTCTGTGTGACTCTTGCGATAGTGGATACCATACTGCCTGCCTTCGCCCTCCTCTGATGATCATCCCAGATGGAGAATGGTTCTGCCCA
CCTTGCCAACATAAACTGCTCTGTGAAAAATTAGAGGAACAGTTGCAGGATTTGGATGTTGCCTTAAAGAAGAAAGAGCGTGCCGAACGA
AGAAAAGAACGCTTGGTGTATGTTGGTATCAGTATTGAAAACATCATTCCTCCACAAGAGCCAGACTTTTCTGAAGATCAAGAAGAAAAG
AAAAAAGATTCAAAAAAATCCAAAGCAAACTTGCTTGAAAGGAGGTCAACAAGAACAAGGAAATGTATAAGCTACAGATTTGATGAGTTT
GATGAAGCAATTGATGAAGCTATTGAAGATGACATCAAAGAAGCCGATGGAGGAGGAGTTGGCCGAGGAAAAGATATCTCCACCATCACA
GGTCATCGTGGGAAAGACATCTCTACTATTTTGGATGAAGAAAGAAAAGAAAATAAACGACCCCAGAGGGCAGCTGCTGCTCGAAGGAAG
AAACGCCGGCGATTAAATGATCTGGACAGTGATAGCAACCTGGATGAAGAAGAGAGCGAGGATGAATTCAAGATCAGTGATGGATCTCAA
GATGAGTTTGTTGTGTCTGATGAAAACCCAGATGAAAGTGAAGAAGATCCGCCATCTAATGATGACAGTGACACTGACTTTTGTAGCCGT
AGACTGAGGCGACACCCCTCTCGGCCAATGAGGCAGAGCAGGCGTTTGCGAAGAAAGACCCCAAAGAAAAAATATTCCGATGATGATGAA
GAGGAGGAATCTGAGGAGAATAGTAGAGACTCTGAAAGTGACTTCAGTGATGATTTTAGTGATGATTTTGTAGAAACTCGGCGAAGGCGG
TCAAGGAGAAATCAGAAAAGACAAATTAACTACAAAGAAGACTCAGAAAGTGACGGTTCCCAGAAGAGTTTGCGACGTGGTAAAGAAATA
AGGCGAGTACACAAGCGAAGACTTTCCAGCTCAGAGAGTGAAGAGAGCTATTTGTCCAAGAACTCTGAAGATGATGAGCTAGCTAAAGAA
TCAAAGCGGTCAGTTCGAAAGCGGGGCCGAAGCACAGACGAGTATTCAGAAGCAGATGAGGAGGAGGAGGAAGAGGAAGGCAAACCATCC
CGCAAACGGCTACACCGGATTGAGACGGATGAGGAGGAGAGTTGTGACAATGCTCATGGAGATGCAAATCAGCCTGCCCGTGACAGCCAG
CCTAGGGTCCTGCCCTCAGAACAAGAGAGCACCAAGAAGCCCTACCGGATAGAAAGTGATGAGGAAGAGGACTTTGAAAATGTAGGCAAA
GTGGGGAGCCCATTGGACTATAGCTTAGTGGACTTACCTTCAACCAATGGACAGAGCCCTGGCAAAGCCATTGAGAACTTGATTGGCAAG
CCTACTGAGAAGTCTCAGACCCCCAAGGACAACAGCACAGCCAGTGCAAGCCTAGCCTCCAATGGGACAAGTGGTGGGCAGGAGGCAGGA
GCACCAGAAGAGGAGGAAGATGAGCTTTTGAGAGTGACTGACCTTGTTGATTATGTCTGTAACAGTGAACAGTTATAAGACTTTTTTTCC
ATTTTTGTGCTAATTTATTCCACGGTAGCTCTCACACCAGCGGGCCAGTTATTAAAAGCTGTTTAATTTTTCCTAGAAAACTCCACTACA
GAATGACTTTTAGAAGAAAAATTTCAACAAATCCTGAAGTCTTTCTGTGAAGTGACCAGTTCTGAACTTTGAAGATAAATAATTGCTGTA
AATTCCTTTTGATTTTCTTTTTCCAGGTTCATGGTCCTTGGTAATTTCATTCATGGAAAAAAATCTTATTATAATAACAACAAAGATTTG
TATATTTTTGACTTTATATTTCCTGAGCTCTCCTGACTTTGTGAAAAAGGGTGGATGAAAATGCATTCCGAATCTGTGAGGGCCCAAAAC
AGAATTTAGGGGTGGGTGAAAGCACTTGTGCTTTAGCTTTTTCATATTAAATATATATTATATTTAAACATTCATGGCATAGATGATGAT
TTACAGACAATTTAAAAGTTCAAGTCTGTACTGTTACAGTTTGAGAATTGTAGATAACATCATACATAAGTCATTTAGTAACAGCCTTTG
TGAAATGAACTTGTTTACTATTGGAGATAACCACACTTAATAAAGAAGAGACAGTGAAAGTACCATCATAATTAACCTAAATTTTTGTTA
TAGCAGAGTTTCTTGTTTAAAAAAAAATAAAATCATCTGAAAAGCATTTGTACAGTAAAATGTATAATGAAGCTTTGCCAACCAGACTGT
GCTAGCAACAAATTTTTTTAAATAAGCTTTATGCAGTGGTAATAAGGTGGCCTCAAATATATTGTGTCTGATGGAGAGTTATTAGTGAAA
TGAATGTGGTCTTTCTTAAGGCCTGGGTGGACTGTAAACTTTGCCAATAGTATAACTCTTGTCTTCTGGCCACTTGATGTTTAAATATCT
GAAATATCATTTTGAAAAAAATACATCTATATATAACATACATGAAGAGATGCTAAGCTGACAGTGATATTTTAGCACATTTGAAGACTG
GGAAGAGATTTTCAGGTGAATTTTAACTGGTCTATTCTTGCCCTTAGTATCTACTTCAAATTGAAGTCTACAAACAAAGCAGTTCCTTTG
GGAGGTTTTTAGTTTGAGTTTTAGCGTGTGTGTGTGTTTGTGTGTGTGCGTGTGCGTGTGTGTGTGTGTTGGAATTTCCTATCTGCCTGG
ATATATTAGCAGAGTTTGAATGTAGTTTTGGCCTTTGGCCATTAGACTTCTATTAAAATTCATTAATAGTCATACAACCAACATAGAGTT
GAATGAGAACTGCCGATGTAATTAATAGGCATGACATCCATTTCAAACATCTCAACACTTTAAAGAAAAGCCCTTTGTTTCAAGAAAAAA
GGGTTTGTAACTAACTAAATACCTAACATGTAATTGACACTAAAATATGAACTTTGTCTTATTTAGTTTCTGTTATAGCTGTAAAATTTC
AGGCAGAGCCATAACATTGTACAGAGTGTAGCACTTGTGATTAAACCTAGCCTGTTAAATCCTGAAACCTTCAACCATTACTTCTGTGAA
TACTTTAGCCCTGGGATTTGGGTTTTTCTGTTCCGGTGTTGTGTCTGTTGCCGGCAATGGACACACCATATCTGCTGCTGGCCCAAGGAA
CGTCATTAATTTTTCTTTCCAAATTAAGTATTATGTGCTAGTCAGTGTATAGTAAAGCACTTCTCTTTTTTATTACTAAAAAGCTGGCAT
TAGATTTGCATTATAAATACCTCTCTAGGAACTTTATACTCCTTTTCCTTCTTCAACAGGTATTGCCCTTAAATCTTATCTTTTGGCCTT
GAAAGTTTATAGCTATTGTTTTTCAGTTGTTCGTTGTTTTGTTTTGTTTCACTTTAGTTCTGTAGTACCTGCCCATTAATATTTTTGCTT
TGATTCTAGCAATGTGTATGTATCTGTATAAAAAATAAAATAATGAAAGCAACCTAAAAATAGGATGCACCAATAGCATGTGGTTCCAAG
TAAGTTGTGATTTTTATTTTGAGACAGTGTTCCACTGGAAGGGAGGGAAGGGCTTACATTCACAGACAGTAAAGCAGGGCTGTGTAAGGA
GCTACATTTACTTAACAGTCTCCTTTCCAGCTAGGTTTGTTTTATTTATTTGCAAGTCAGCTAAGAATTAACCTTTTAAACCATCTAAAA
CAGGCAAGCAATATAAAGATTTCTACTAGTGCAAGGTAAGTGGTTTGAATATACAAGTGCCCTTTCCTGCCACCCAGTCTCACTACCGTT
TTAGTCCTGCAGCTGGGTAAAGCCACTATTGTGTGGAAACTCTCCCATGTGCCCTGTCTCTACCTCTGGACACACCAGCTCCTTCTTCCA
CCTATTCTATTCCTCAGTTAAGCCAAGTGATCAGAAGTAGTATTAAATGGGTAGATAATTTTAACAGGATGCCTAATGTGAAATAAGGAG
TTATTTTTACTCTTCTACTATAGAAAGCCTAAGGTAATTCTTACCATCTCAAAGACTGAGTATTCCATTTAGGTTTGGAGACCACTTGTG
CTGTGCTGCCTGATATTTACCAAACTTGAATAAGTGTTCGTCAACTTGATAGTGAATGTACCCCTTCTCACCTTATATTTTGATTAAATC
AATTAACTATAGGTCATCTACCAAGAATGTAATCCAAGCGGTTGATAAAACATTATTAGGCAGATAGATTATTGATTATTAAATTTTGAG
CAGTGCAAAAACGGTTTTGCTGCTTGGAGTTCAGATTCAGTCCCTCAAAGAGTTTATGATCACTGAAATACACTCTGAAGGTATTCTGAA
GAAGTTAAAAAATTTTAGAAAACGAAATGTTCTGTATACAAAGACAATACAGTCACTACGAACTGCAGAAAGTATAGGAAAGCAGTAATT
GATGTAGAGTTTAGACAGTCTTGGATCTTTTTTAGAGCACTAACCATGGATTTAGACTCAAAATAGCTGCTACATAATAGAGCCCTTTAA
TAATTTAAACCCCCCTTGTTGAAATACAAGTTGGACTCCCAGTGTCAAACTCTAGACTGTAGCTAATGTATTAAAGGGAGATGTAGATTA
ATATTCAGTATATTTAGTTTGCAATTTCTGAAAAGGTTTGAAAACTAGTCAGCTTTTCACACAGCAGAAGCTTTGAACTGAAATATGTGT
GAAAAGGACGCAGACTGAAAACGTTTTGGTTTTGTACATCAGTGCTGATGAAATTAGTGTAAAACATTTTCCATCATTGGCACATTACTG
CAAAATGATGGCAGAGATATTTTCAAGAATGTACATCAAGTTATATTTCCTTGACATCCTTTTTTCAATTGGTCAAGGTTACAGATTCAG
AGGATAAAGGGTAGTTTCATTTAGAATAAATTCATGTCTACTGGCAATCTATATATAAAAGTGACCTGCCCAAGAACCAAAAACTTTAAA
TGCTAATGAAGCTTTTGAAAAATAATTTTTAAACAAATTAATTTTAAAAGGGTGTTACACGTACCCAGTTTTTACTTTTTAGTTGATGAA
ACCCATCCTATAATATACATTTGAGCAAAGTACACATATTAAGAAAAACATGGACATTTACTTGTTTAATAGTCAAAATGATGAGGAAAT
GTTAGCTGTTTTTAAGTGGGACTGGTGGGGTGTCCTTTGTCACAAGGAATGCTTTTTTAGCTTGTTTGTGGGCATAAGAGATGTTAACCC
TTTGCTGATTCTACCACACAACTGTAAAGAACCTAATGAATCTACAAGTTTAATATTCAGAAAAAGCTAGGAACTCCGCTCTTTACCAGT
ACAGTGGAACAGGCCCGTTATTCAAGGTGATGCCTCACAGCTATAGAACAACTATTCAAAGACCCAGAGTTAAATGGTACATGTGTATAT
GTGTGTGTGTGTGTGCACACGCACACACTTCAGATAAGTATCAGAAAAAATAAAAATGAATCCATCATTAACTTGAAAGAAATAAGATGG
CTGCATTGCAACAGATACAAATATTATGAACATCATTTAATTACAGAAAATCTAGACAACAGTTTCTCCTGATGTTTGACATTCTCAAAA
TATATTCCTCATTCTCGAAGAAGCAGAGAATGCCAAGGCTGCATATCTGCTGTAATCTACCTAGCCCTCTTCTGCTTAATATGATCCATT
ATTGAATCTTCTCAGATTAAAATCCATTCCTATATCATCTACCTTTCCCAAAGTGTGTGCCTGTAAACCTACCTTGGAAGTGGCAAGTTA
ACTGATTTTTTTGTGTCATTTTTATACCAATCCTTAAGGTCAAAGCCTTTTGCTATCAATGTATTTAAACTGAGTTGCTATATGTTCACT
AATTTGTTTTCAAAATGTTTTGCTCCAACTTAAATTATCTTTTAACATCTTTTGAGTGCCAAGAATTGCTAAGTAACTGTAATATGTTGA
AGAGAGTAATTGCCAAGCAAGCAGTCATAAGCCAAAATGTAATGAGCTTAGTATATAACCACTTTAGAGTATACACTCACCACTTTTTGT
ATTCATTCATGCAAACCCTCCTGGAAGTCGATTAGAAGAGGATCCAATTTGTGGACCTTTTTTCCTCCTTTTGGACACCTGAGCACAATT
TTTTTTTTCCTTTCATATTTATACCACTTTGGAAAATTCAGTAAACCCAATTCTGGCACATCATAATGGTTTCAGTTAGTGAAGATGTTT
ATTTTAATAACTTTAAAATATGACTATCCTATACATAAGTTATATAAGAGGGCATAACAATAGATGAGTAGAAATTTATAAAATTTCTTG
GATATTTTGAATGAGAAAAAAACATTTTTAAAGGAATTTTGTTTTTTCCTTTTTTGGCCAAACCGGTACAAGTTAGAAAGTGTGCTAAGG
ACTGAATACTTGCCTCGTGCTTTTTGCCACTGGATGATGTAAGTTAAGAATGGAATTGTTAATCCTAAGTATATATTTTCTTGACTTTCA
TCAGTTTCTAAAGAAATCTAATTTAAGTGTTTTGCGGTTTTGTTTGATCTGTATTTATTGAGTTCTGGTCATAGACCAGCAGCTTGCACG
TCATGCTCATGAACAGCCAGAACATAGTTATTGGGGAACTTCATGGCTCAAAACCTTCTGAATCATTTAACTTATTTTGTATGTTGCAAA
AAAAAAAAAAAAGTTTATTTTGCTTGAGAGTCACCTTTTTTTAAAAAAAATAACTGTACAGCTTTTAAGGGATGGGAGGTGGGAAAATAC
CCTAAAATAGGATGTAGATTTTTTACAATTGTGTTTATGCTAGATCATCTACAGGTGCATTATGTAATTAAACCTAAAATTGTTTAAAAA
TTTGTGCCATGTCTTTTTCATTCTCCTGCCCTTTAGCAGAATTGGTGCATGTCAACTGCTATGTGGACAAGCCTTGAAATTAGAGTAACA
AGCCCTGTCTCCAAAGCTTTAAGGTCACTGCATGAAAATTGCACACACACACACACACACACACACATCTAGCTTATATTAGTAAATGGA
TTTTCAGGATCAGAACAGCTACAGTAGCCCAGATTTGGCTGTTAACAGCATATTCTTACAGCACATGATTTTTGTGATGCCTAACTAGGG
TATTCTCAATGTTAGTCTGGTGTTCTATTCTCTTTCAAAGTAGCTTCTTGAGATGGTATCTGTTGTAGCTTGCCCAAACCTGCCATGAGG
TTGTGTGTACACTTTGAAAGGGTATGTCCTATGCTAAGATGGTGGTAGAGCAGGGCTTGATTTTAATCTATTCATATAAAAGAAGGAAAA
AACTAGAATTGGTCTATTTGGTTATTCAGTGGACTTAATTCCACAGGAATAGTTGTCTGCTGAAGCGTGGCAGCAAGAGAAGTCAAATTC
AAGTTTCAGTTCCTTCCTTATTCACTAAGTATTTTGAAATCTTGTAGAACTTCTGATTCTAGCACAGTCTTTTACATGGCACATTTTACC
ATGGTATATTCACAGCTTCGTTTAAATGTCAGTACTTTTTCCCATCTGATAATTTTGCCATTCTAATTTCTCACCTTTGTAGTACAAGTG
TATTCTTGAAAATAATTAAATTCATCTAAGTGTGTCATAATTTCAATCAAAGCTATATTCATGTGTTGCCAGCGTCAGTTTTTTGCTATC
CTCATTCAGAAGGGAAGCCTGCAGATCATGAGTTTCCATATGAAGAATACAAATTCCACATAAAAATTTATAAATGGTATCTTTAGAATT
TTGATTTAAAGTAATAGCTGGAATTCAGGGACTGATCAGAATGCCTCTTGAATTTTCCAACATGCTTATATGAAATGCTTTATTTTCCTA
TGCGTTAAAAAAAATATTCCTGGAATAGGTTCTCAGAATGTTTTATTTGGTTTCTAGGAGATGAGATTTAAAGCAGAAGCTCCAAGATTG
GCATAAAACTAACTCTTGAGGTAATCAGGACCATGCTGTTAGTCAAATAGAAGCTGGAGTGCTCTCTGTCACATAATGTACTGCATGTGT
GTGGGGGTGGGGGGGCAGGGAAGATCAGAAAACTGGAAATGTAATTCTGATAACACGCAAAGTAAATTGTGCATTAAAAGTATGGGAATT
CTTGGTAGCTTAAAGCTTCAGGGGTTAACTTCAGTGTATGAACACCTAGTGTGTTAGAATTGCAGTGCATAGTTGTTTAAATACAATATT
CCTTGTAAGTGACAACCAAAATATGTTGTGGCTGGTGCCAGTATTTTTGTTAATGAAATGTTCAGTGTCTCACTACAGTCTGATCAGAAC
TCTTGGTGTTATAAGCCAGGCCTAAAGCCATTTTATAGCTATTGGCCTAATTGTGTAACTTTTTCTTTCAAAATGTTTTATTATAATACT

>35197_35197_1_GTF2F2-RSF1_GTF2F2_chr13_45725966_ENST00000340473_RSF1_chr11_77413540_ENST00000308488_length(amino acids)=1325AA_BP=128
MFRTPAPQPCGSWGRCCIPHASTGCRPMAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNEDLA
NIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSEEQKESEKMKSEEQPMDLENRSTANVLEETTVKKEKEDEKELVKLPVIVKLE
KPLPENEEKKIIKEESDSFKENVKPIKVEVKECRADPKDTKSSMEKPVAQEPERIEFGGNIKSSHEITEKSTEETEKLKNDQQAKIPLKK
REIKLSDDFDSPVKGPLCKSVTPTKEFLKDEIKQEEETCKRISTITALGHEGKQLVNGEVSDERVAPNFKTEPIETKFYETKEESYSPSK
DRNIITEGNGTESLNSVITSMKTGELEKETAPLRKDADSSISVLEIHSQKAQIEEPDPPEMETSLDSSEMAKDLSSKTALSSTESCTMKG
EEKSPKTKKDKRPPILECLEKLEKSKKTFLDKDAQRLSPIPEEVPKSTLESEKPGSPEAAETSPPSNIIDHCEKLASEKEVVECQSTSTV
GGQSVKKVDLETLKEDSEFTKVEMDNLDNAQTSGIEEPSETKGSMQKSKFKYKLVPEEETTASENTEITSERQKEGIKLTIRISSRKKKP
DSPPKVLEPENKQEKTEKEEEKTNVGRTLRRSPRISRPTAKVAEIRDQKADKKRGEGEDEVEEESTALQKTDKKEILKKSEKDTNSKVSK
VKPKGKVRWTGSRTRGRWKYSSNDESEGSGSEKSSAASEEEEEKESEEAILADDDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLM
IIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENIIPPQEPDFSEDQEEKKKDSKKSKANLLERRSTRTR
KCISYRFDEFDEAIDEAIEDDIKEADGGGVGRGKDISTITGHRGKDISTILDEERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESE
DEFKISDGSQDEFVVSDENPDESEEDPPSNDDSDTDFCSRRLRRHPSRPMRQSRRLRRKTPKKKYSDDDEEEESEENSRDSESDFSDDFS
DDFVETRRRRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEESYLSKNSEDDELAKESKRSVRKRGRSTDEYSEADE
EEEEEEGKPSRKRLHRIETDEEESCDNAHGDANQPARDSQPRVLPSEQESTKKPYRIESDEEEDFENVGKVGSPLDYSLVDLPSTNGQSP

--------------------------------------------------------------
>35197_35197_2_GTF2F2-RSF1_GTF2F2_chr13_45725966_ENST00000340473_RSF1_chr11_77413540_ENST00000360355_length(transcript)=4725nt_BP=445nt
TTCCCAGTGTTCTGGCAGGTAAGGAACGCCGGCTCTTCGCCTCTCAGCGCGGCTTGTCCTTTGTTCCGGACGCCCGCTCCTCAGCCCTGC
GGCTCCTGGGGTCGCTGCTGCATCCCGCACGCCTCCACCGGCTGCAGACCCATGGCCGAGCGCGGGGAACTCGACTTGACCGGCGCCAAA
CAGAACACAGGAGTGTGGCTAGTCAAGGTTCCTAAATATTTGTCACAGCAATGGGCTAAAGCCTCTGGAAGAGGTGAAGTTGGGAAACTG
CGGATTGCCAAGACTCAAGGAAGGACTGAGGTGTCATTTACTTTGAATGAGGATCTTGCAAATATTCATGATATTGGTGGAAAACCAGCT
TCAGTCAGTGCTCCTAGAGAACATCCATTTGTCTTGCAAAGTGTTGGAGGACAGACATTAACAGTATTTACTGAGAGCTCATCAGAGGAA
CAGAAAGAAAGTGAAAAGATGAAAAGTGAGGAGCAGCCTATGGATTTAGAAAACCGTTCTACAGCCAATGTTCTAGAAGAGACTACTGTG
AAAAAAGAAAAAGAAGATGAAAAGGAACTTGTGAAACTGCCAGTCATAGTGAAGCTAGAAAAACCTTTGCCAGAAAATGAAGAAAAAAAG
ATTATCAAAGAAGAAAGTGATTCCTTCAAGGAAAATGTCAAACCCATTAAAGTTGAGGTGAAGGAATGTAGAGCAGATCCTAAAGATACC
AAAAGTAGCATGGAGAAGCCAGTGGCACAGGAGCCTGAAAGGATCGAATTTGGTGGCAATATTAAATCTTCTCACGAAATTACTGAGAAA
TCTACTGAAGAAACTGAGAAACTTAAAAATGACCAGCAGGCCAAGATACCACTAAAAAAACGAGAAATTAAACTGAGTGATGATTTTGAC
AGTCCAGTCAAGGGACCTTTGTGTAAATCAGTTACTCCAACAAAAGAGTTTTTGAAAGATGAAATAAAACAAGAGGAAGAGACTTGTAAA
AGGATCTCTACAATCACTGCTTTGGGTCATGAAGGGAAACAGCTGGTAAATGGAGAAGTTAGTGATGAAAGGGTAGCTCCAAATTTTAAG
ACAGAACCAATAGAGACAAAGTTTTATGAGACAAAGGAAGAGAGCTATAGCCCCTCTAAGGACAGAAATATCATCACGGAGGGAAATGGA
ACAGAGTCCTTAAATTCTGTCATAACAAGTATGAAAACAGGTGAGCTTGAGAAAGAAACAGCCCCTTTGAGGAAAGATGCAGATAGTTCA
ATATCAGTCTTAGAGATCCATAGTCAAAAAGCACAAATAGAGGAACCCGATCCTCCAGAAATGGAAACTTCTCTTGATTCTTCTGAGATG
GCAAAAGATCTCTCTTCAAAAACTGCTTTATCTTCCACCGAGTCGTGTACCATGAAAGGTGAAGAGAAGTCTCCCAAAACTAAGAAGGAT
AAGCGCCCACCAATCCTAGAATGTCTTGAAAAGTTAGAGAAGTCCAAAAAGACTTTTCTTGATAAGGACGCACAAAGATTGAGTCCAATA
CCAGAAGAAGTTCCAAAGAGTACTCTAGAGTCAGAAAAGCCTGGCTCTCCTGAGGCAGCTGAAACTTCTCCACCATCTAATATCATTGAC
CACTGTGAGAAACTAGCCTCAGAAAAAGAAGTGGTAGAATGCCAGAGTACAAGTACTGTTGGTGGCCAGTCTGTGAAAAAAGTAGACCTA
GAAACCCTAAAAGAGGATTCTGAGTTCACAAAGGTAGAAATGGATAATCTGGACAATGCCCAGACCTCTGGCATAGAGGAGCCTTCTGAG
ACAAAGGGTTCTATGCAAAAAAGCAAATTCAAATATAAGTTGGTTCCTGAAGAAGAAACCACTGCCTCAGAAAATACAGAGATAACCTCT
GAAAGGCAGAAAGAGGGCATCAAATTAACAATCAGGATATCAAGTCGGAAAAAGAAGCCCGATTCTCCCCCCAAAGTTCTAGAACCAGAA
AACAAGCAAGAGAAGACAGAAAAGGAAGAGGAGAAAACAAATGTGGGTCGTACTTTAAGAAGATCTCCAAGAATATCTAGACCCACTGCA
AAAGTGGCTGAGATCAGAGATCAGAAAGCTGATAAAAAAAGAGGGGAAGGAGAAGATGAGGTGGAAGAAGAGTCAACAGCTTTGCAAAAA
ACTGACAAAAAGGAAATTTTGAAAAAATCAGAGAAAGATACAAATTCTAAAGTAAGCAAGGTAAAACCCAAAGGCAAAGTTCGATGGACT
GGTTCTCGGACACGTGGCAGATGGAAATATTCCAGCAATGATGAAAGTGAAGGGTCTGGCAGTGAAAAATCATCTGCAGCTTCAGAAGAG
GAGGAAGAAAAGGAAAGTGAAGAAGCCATCCTAGCAGATGATGATGAACCATGCAAAAAATGTGGCCTTCCAAACCATCCTGAGCTAATT
CTTCTGTGTGACTCTTGCGATAGTGGATACCATACTGCCTGCCTTCGCCCTCCTCTGATGATCATCCCAGATGGAGAATGGTTCTGCCCA
CCTTGCCAACATAAACTGCTCTGTGAAAAATTAGAGGAACAGTTGCAGGATTTGGATGTTGCCTTAAAGAAGAAAGAGCGTGCCGAACGA
AGAAAAGAACGCTTGGTGTATGTTGGTATCAGTATTGAAAACATCATTCCTCCACAAGAGCCAGACTTTTCTGAAGATCAAGAAGAAAAG
AAAAAAGATTCAAAAAAATCCAAAGCAAACTTGCTTGAAAGGAGGTCAACAAGAACAAGGAAATGTATAAGCTACAGATTTGATGAGTTT
GATGAAGCAATTGATGAAGCTATTGAAGATGACATCAAAGAAGCCGATGGAGGAGGAGTTGGCCGAGGAAAAGATATCTCCACCATCACA
GGTCATCGTGGGAAAGACATCTCTACTATTTTGGATGAAGAAAGAAAAGAAAATAAACGACCCCAGAGGGCAGCTGCTGCTCGAAGGAAG
AAACGCCGGCGATTAAATGATCTGGACAGTGATAGCAACCTGGATGAAGAAGAGAGCGAGGATGAATTCAAGATCAGTGATGGATCTCAA
GATGAGTTTGTTGTGTCTGATGAAAACCCAGATGAAAGTGAAGAAGATCCGCCATCTAATGATGACAGTGACACTGACTTTTGTAGCCGT
AGACTGAGGCGACACCCCTCTCGGCCAATGAGGCAGAGCAGGCGTTTGCGAAGAAAGACCCCAAAGAAAAAATATTCCGATGATGATGAA
GAGGAGGAATCTGAGGAGAATAGTAGAGACTCTGAAAGTGACTTCAGTGATGATTTTAGTGATGATTTTGTAGAAACTCGGCGAAGGCGG
TCAAGGAGAAATCAGAAAAGACAAATTAACTACAAAGAAGACTCAGAAAGTGACGGTTCCCAGAAGAGTTTGCGACGTGGTAAAGAAATA
AGGCGAGTACACAAGCGAAGACTTTCCAGCTCAGAGAGTGAAGAGAGCTATTTGTCCAAGAACTCTGAAGATGATGAGCTAGCTAAAGAA
TCAAAGCGGTCAGTTCGAAAGCGGGGCCGAAGCACAGACGAGTATTCAGAAGCAGATGAGGAGGAGGAGGAAGAGGAAGGCAAACCATCC
CGCAAACGGCTACACCGGATTGAGACGGATGAGGAGGAGAGTTGTGACAATGCTCATGGAGATGCAAATCAGCCTGCCCGTGACAGCCAG
CCTAGGGTCCTGCCCTCAGAACAAGAGAGCACCAAGAAGCCCTACCGGATAGAAAGTGATGAGGAAGAGGACTTTGAAAATGTAGGCAAA
GTGGGGAGCCCATTGGACTATAGCTTAGTGGACTTACCTTCAACCAATGGACAGAGCCCTGGCAAAGCCATTGAGAACTTGATTGGCAAG
CCTACTGAGAAGTCTCAGACCCCCAAGGACAACAGCACAGCCAGTGCAAGCCTAGCCTCCAATGGGACAAGTGGTGGGCAGGAGGCAGGA
GCACCAGAAGAGGAGGAAGATGAGCTTTTGAGAGTGACTGACCTTGTTGATTATGTCTGTAACAGTGAACAGTTATAAGACTTTTTTTCC
ATTTTTGTGCTAATTTATTCCACGGTAGCTCTCACACCAGCGGGCCAGTTATTAAAAGCTGTTTAATTTTTCCTAGAAAACTCCACTACA
GAATGACTTTTAGAAGAAAAATTTCAACAAATCCTGAAGTCTTTCTGTGAAGTGACCAGTTCTGAACTTTGAAGATAAATAATTGCTGTA
AATTCCTTTTGATTTTCTTTTTCCAGGTTCATGGTCCTTGGTAATTTCATTCATGGAAAAAAATCTTATTATAATAACAACAAAGATTTG
TATATTTTTGACTTTATATTTCCTGAGCTCTCCTGACTTTGTGAAAAAGGGTGGATGAAAATGCATTCCGAATCTGTGAGGGCCCAAAAC
AGAATTTAGGGGTGGGTGAAAGCACTTGTGCTTTAGCTTTTTCATATTAAATATATATTATATTTAAACATTCATGGCATAGATGATGAT
TTACAGACAATTTAAAAGTTCAAGTCTGTACTGTTACAGTTTGAGAATTGTAGATAACATCATACATAAGTCATTTAGTAACAGCCTTTG
TGAAATGAACTTGTTTACTATTGGAGATAACCACACTTAATAAAGAAGAGACAGTGAAAGTACCATCATAATTAACCTAAATTTTTGTTA

>35197_35197_2_GTF2F2-RSF1_GTF2F2_chr13_45725966_ENST00000340473_RSF1_chr11_77413540_ENST00000360355_length(amino acids)=1325AA_BP=128
MFRTPAPQPCGSWGRCCIPHASTGCRPMAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNEDLA
NIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSEEQKESEKMKSEEQPMDLENRSTANVLEETTVKKEKEDEKELVKLPVIVKLE
KPLPENEEKKIIKEESDSFKENVKPIKVEVKECRADPKDTKSSMEKPVAQEPERIEFGGNIKSSHEITEKSTEETEKLKNDQQAKIPLKK
REIKLSDDFDSPVKGPLCKSVTPTKEFLKDEIKQEEETCKRISTITALGHEGKQLVNGEVSDERVAPNFKTEPIETKFYETKEESYSPSK
DRNIITEGNGTESLNSVITSMKTGELEKETAPLRKDADSSISVLEIHSQKAQIEEPDPPEMETSLDSSEMAKDLSSKTALSSTESCTMKG
EEKSPKTKKDKRPPILECLEKLEKSKKTFLDKDAQRLSPIPEEVPKSTLESEKPGSPEAAETSPPSNIIDHCEKLASEKEVVECQSTSTV
GGQSVKKVDLETLKEDSEFTKVEMDNLDNAQTSGIEEPSETKGSMQKSKFKYKLVPEEETTASENTEITSERQKEGIKLTIRISSRKKKP
DSPPKVLEPENKQEKTEKEEEKTNVGRTLRRSPRISRPTAKVAEIRDQKADKKRGEGEDEVEEESTALQKTDKKEILKKSEKDTNSKVSK
VKPKGKVRWTGSRTRGRWKYSSNDESEGSGSEKSSAASEEEEEKESEEAILADDDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLM
IIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENIIPPQEPDFSEDQEEKKKDSKKSKANLLERRSTRTR
KCISYRFDEFDEAIDEAIEDDIKEADGGGVGRGKDISTITGHRGKDISTILDEERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESE
DEFKISDGSQDEFVVSDENPDESEEDPPSNDDSDTDFCSRRLRRHPSRPMRQSRRLRRKTPKKKYSDDDEEEESEENSRDSESDFSDDFS
DDFVETRRRRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEESYLSKNSEDDELAKESKRSVRKRGRSTDEYSEADE
EEEEEEGKPSRKRLHRIETDEEESCDNAHGDANQPARDSQPRVLPSEQESTKKPYRIESDEEEDFENVGKVGSPLDYSLVDLPSTNGQSP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for GTF2F2-RSF1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GTF2F2-RSF1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GTF2F2-RSF1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource