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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:H2AFY-CNOT6 (FusionGDB2 ID:35491)

Fusion Gene Summary for H2AFY-CNOT6

check button Fusion gene summary
Fusion gene informationFusion gene name: H2AFY-CNOT6
Fusion gene ID: 35491
HgeneTgene
Gene symbol

H2AFY

CNOT6

Gene ID

9555

57472

Gene namemacroH2A.1 histoneCCR4-NOT transcription complex subunit 6
SynonymsH2A.y|H2A/y|H2AF12M|H2AFY|MACROH2A1.1|mH2A1|macroH2A1.2CCR4|Ccr4a
Cytomap

5q31.1

5q35.3

Type of geneprotein-codingprotein-coding
Descriptioncore histone macro-H2A.1H2A histone family member Yhistone H2A.yhistone macroH2A1histone macroH2A1.1histone macroH2A1.2medulloblastoma antigen MU-MB-50.205CCR4-NOT transcription complex subunit 6carbon catabolite repression 4 proteincarbon catabolite repressor protein 4 homologcytoplasmic deadenylase
Modification date2020031320200329
UniProtAcc.

Q96LI5

Ensembl transtripts involved in fusion geneENST00000304332, ENST00000510038, 
ENST00000511689, ENST00000512507, 
ENST00000312469, ENST00000423969, 
ENST00000502447, ENST00000261951, 
ENST00000393356, 
Fusion gene scores* DoF score8 X 9 X 4=2884 X 5 X 3=60
# samples 95
** MAII scorelog2(9/288*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/60*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: H2AFY [Title/Abstract] AND CNOT6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointH2AFY(134688636)-CNOT6(179991489), # samples:5
Anticipated loss of major functional domain due to fusion event.H2AFY-CNOT6 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
H2AFY-CNOT6 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneH2AFY

GO:0007549

dosage compensation

15053874

HgeneH2AFY

GO:0034184

positive regulation of maintenance of mitotic sister chromatid cohesion

26373281

HgeneH2AFY

GO:1904815

negative regulation of protein localization to chromosome, telomeric region

26373281

TgeneCNOT6

GO:0043928

exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay

20065043

TgeneCNOT6

GO:2000327

positive regulation of nuclear receptor transcription coactivator activity

18180299


check buttonFusion gene breakpoints across H2AFY (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CNOT6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E2-A15E-01AH2AFYchr5

134688636

-CNOT6chr5

179991489

+
ChimerDB4BRCATCGA-E2-A15E-06AH2AFYchr5

134688636

-CNOT6chr5

179991489

+
ChimerDB4BRCATCGA-E2-A15EH2AFYchr5

134688635

-CNOT6chr5

179991488

+


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Fusion Gene ORF analysis for H2AFY-CNOT6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000304332ENST00000502447H2AFYchr5

134688636

-CNOT6chr5

179991489

+
5CDS-3UTRENST00000304332ENST00000502447H2AFYchr5

134688635

-CNOT6chr5

179991488

+
5CDS-3UTRENST00000510038ENST00000502447H2AFYchr5

134688636

-CNOT6chr5

179991489

+
5CDS-3UTRENST00000510038ENST00000502447H2AFYchr5

134688635

-CNOT6chr5

179991488

+
5CDS-3UTRENST00000511689ENST00000502447H2AFYchr5

134688636

-CNOT6chr5

179991489

+
5CDS-3UTRENST00000511689ENST00000502447H2AFYchr5

134688635

-CNOT6chr5

179991488

+
5UTR-3CDSENST00000512507ENST00000261951H2AFYchr5

134688636

-CNOT6chr5

179991489

+
5UTR-3CDSENST00000512507ENST00000261951H2AFYchr5

134688635

-CNOT6chr5

179991488

+
5UTR-3CDSENST00000512507ENST00000393356H2AFYchr5

134688636

-CNOT6chr5

179991489

+
5UTR-3CDSENST00000512507ENST00000393356H2AFYchr5

134688635

-CNOT6chr5

179991488

+
5UTR-3UTRENST00000512507ENST00000502447H2AFYchr5

134688636

-CNOT6chr5

179991489

+
5UTR-3UTRENST00000512507ENST00000502447H2AFYchr5

134688635

-CNOT6chr5

179991488

+
Frame-shiftENST00000304332ENST00000261951H2AFYchr5

134688636

-CNOT6chr5

179991489

+
Frame-shiftENST00000304332ENST00000261951H2AFYchr5

134688635

-CNOT6chr5

179991488

+
Frame-shiftENST00000304332ENST00000393356H2AFYchr5

134688636

-CNOT6chr5

179991489

+
Frame-shiftENST00000304332ENST00000393356H2AFYchr5

134688635

-CNOT6chr5

179991488

+
Frame-shiftENST00000511689ENST00000261951H2AFYchr5

134688636

-CNOT6chr5

179991489

+
Frame-shiftENST00000511689ENST00000261951H2AFYchr5

134688635

-CNOT6chr5

179991488

+
Frame-shiftENST00000511689ENST00000393356H2AFYchr5

134688636

-CNOT6chr5

179991489

+
Frame-shiftENST00000511689ENST00000393356H2AFYchr5

134688635

-CNOT6chr5

179991488

+
In-frameENST00000510038ENST00000261951H2AFYchr5

134688636

-CNOT6chr5

179991489

+
In-frameENST00000510038ENST00000261951H2AFYchr5

134688635

-CNOT6chr5

179991488

+
In-frameENST00000510038ENST00000393356H2AFYchr5

134688636

-CNOT6chr5

179991489

+
In-frameENST00000510038ENST00000393356H2AFYchr5

134688635

-CNOT6chr5

179991488

+
intron-3CDSENST00000312469ENST00000261951H2AFYchr5

134688636

-CNOT6chr5

179991489

+
intron-3CDSENST00000312469ENST00000261951H2AFYchr5

134688635

-CNOT6chr5

179991488

+
intron-3CDSENST00000312469ENST00000393356H2AFYchr5

134688636

-CNOT6chr5

179991489

+
intron-3CDSENST00000312469ENST00000393356H2AFYchr5

134688635

-CNOT6chr5

179991488

+
intron-3CDSENST00000423969ENST00000261951H2AFYchr5

134688636

-CNOT6chr5

179991489

+
intron-3CDSENST00000423969ENST00000261951H2AFYchr5

134688635

-CNOT6chr5

179991488

+
intron-3CDSENST00000423969ENST00000393356H2AFYchr5

134688636

-CNOT6chr5

179991489

+
intron-3CDSENST00000423969ENST00000393356H2AFYchr5

134688635

-CNOT6chr5

179991488

+
intron-3UTRENST00000312469ENST00000502447H2AFYchr5

134688636

-CNOT6chr5

179991489

+
intron-3UTRENST00000312469ENST00000502447H2AFYchr5

134688635

-CNOT6chr5

179991488

+
intron-3UTRENST00000423969ENST00000502447H2AFYchr5

134688636

-CNOT6chr5

179991489

+
intron-3UTRENST00000423969ENST00000502447H2AFYchr5

134688635

-CNOT6chr5

179991488

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000510038H2AFYchr5134688636-ENST00000261951CNOT6chr5179991489+62628201322108658
ENST00000510038H2AFYchr5134688636-ENST00000393356CNOT6chr5179991489+63148201322108658
ENST00000510038H2AFYchr5134688635-ENST00000261951CNOT6chr5179991488+62628201322108658
ENST00000510038H2AFYchr5134688635-ENST00000393356CNOT6chr5179991488+63148201322108658

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000510038ENST00000261951H2AFYchr5134688636-CNOT6chr5179991489+0.000171460.99982846
ENST00000510038ENST00000393356H2AFYchr5134688636-CNOT6chr5179991489+0.0001662720.9998337
ENST00000510038ENST00000261951H2AFYchr5134688635-CNOT6chr5179991488+0.000171460.99982846
ENST00000510038ENST00000393356H2AFYchr5134688635-CNOT6chr5179991488+0.0001662720.9998337

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Fusion Genomic Features for H2AFY-CNOT6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
H2AFYchr5134688635-CNOT6chr5179991488+8.18E-050.9999182
H2AFYchr5134688635-CNOT6chr5179991488+8.18E-050.9999182
H2AFYchr5134688635-CNOT6chr5179991488+8.18E-050.9999182
H2AFYchr5134688635-CNOT6chr5179991488+8.18E-050.9999182
H2AFYchr5134688635-CNOT6chr5179991488+8.18E-050.9999182
H2AFYchr5134688635-CNOT6chr5179991488+8.18E-050.9999182

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for H2AFY-CNOT6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:134688636/chr5:179991489)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CNOT6

Q96LI5

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation-dependent degradation of CDKN1B mRNA. Its mRNA deadenylase activity can be inhibited by TOB1. Mediates cell proliferation and cell survival and prevents cellular senescence. {ECO:0000269|PubMed:17452450, ECO:0000269|PubMed:18377426, ECO:0000269|PubMed:21233283}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneH2AFYchr5:134688635chr5:179991488ENST00000304332-69118_162228372.0Compositional biasNote=Lys-rich
HgeneH2AFYchr5:134688635chr5:179991488ENST00000510038-69118_162229373.0Compositional biasNote=Lys-rich
HgeneH2AFYchr5:134688635chr5:179991488ENST00000511689-69118_162229373.0Compositional biasNote=Lys-rich
HgeneH2AFYchr5:134688636chr5:179991489ENST00000304332-69118_162228372.0Compositional biasNote=Lys-rich
HgeneH2AFYchr5:134688636chr5:179991489ENST00000510038-69118_162229373.0Compositional biasNote=Lys-rich
HgeneH2AFYchr5:134688636chr5:179991489ENST00000511689-69118_162229373.0Compositional biasNote=Lys-rich
HgeneH2AFYchr5:134688635chr5:179991488ENST00000304332-692_117228372.0DomainNote=Histone H2A
HgeneH2AFYchr5:134688635chr5:179991488ENST00000510038-692_117229373.0DomainNote=Histone H2A
HgeneH2AFYchr5:134688635chr5:179991488ENST00000511689-692_117229373.0DomainNote=Histone H2A
HgeneH2AFYchr5:134688636chr5:179991489ENST00000304332-692_117228372.0DomainNote=Histone H2A
HgeneH2AFYchr5:134688636chr5:179991489ENST00000510038-692_117229373.0DomainNote=Histone H2A
HgeneH2AFYchr5:134688636chr5:179991489ENST00000511689-692_117229373.0DomainNote=Histone H2A
TgeneCNOT6chr5:134688635chr5:179991488ENST00000261951312153_557128558.0RegionNuclease domain
TgeneCNOT6chr5:134688635chr5:179991488ENST00000393356514153_557128558.0RegionNuclease domain
TgeneCNOT6chr5:134688636chr5:179991489ENST00000261951312153_557128558.0RegionNuclease domain
TgeneCNOT6chr5:134688636chr5:179991489ENST00000393356514153_557128558.0RegionNuclease domain

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneH2AFYchr5:134688635chr5:179991488ENST00000312469-19118_1620370.0Compositional biasNote=Lys-rich
HgeneH2AFYchr5:134688636chr5:179991489ENST00000312469-19118_1620370.0Compositional biasNote=Lys-rich
HgeneH2AFYchr5:134688635chr5:179991488ENST00000304332-69184_370228372.0DomainMacro
HgeneH2AFYchr5:134688635chr5:179991488ENST00000312469-19184_3700370.0DomainMacro
HgeneH2AFYchr5:134688635chr5:179991488ENST00000312469-192_1170370.0DomainNote=Histone H2A
HgeneH2AFYchr5:134688635chr5:179991488ENST00000510038-69184_370229373.0DomainMacro
HgeneH2AFYchr5:134688635chr5:179991488ENST00000511689-69184_370229373.0DomainMacro
HgeneH2AFYchr5:134688636chr5:179991489ENST00000304332-69184_370228372.0DomainMacro
HgeneH2AFYchr5:134688636chr5:179991489ENST00000312469-19184_3700370.0DomainMacro
HgeneH2AFYchr5:134688636chr5:179991489ENST00000312469-192_1170370.0DomainNote=Histone H2A
HgeneH2AFYchr5:134688636chr5:179991489ENST00000510038-69184_370229373.0DomainMacro
HgeneH2AFYchr5:134688636chr5:179991489ENST00000511689-69184_370229373.0DomainMacro
TgeneCNOT6chr5:134688635chr5:179991488ENST00000261951312121_143128558.0RepeatNote=LRR 4
TgeneCNOT6chr5:134688635chr5:179991488ENST0000026195131252_73128558.0RepeatNote=LRR 1
TgeneCNOT6chr5:134688635chr5:179991488ENST0000026195131275_96128558.0RepeatNote=LRR 2
TgeneCNOT6chr5:134688635chr5:179991488ENST0000026195131298_120128558.0RepeatNote=LRR 3
TgeneCNOT6chr5:134688635chr5:179991488ENST00000393356514121_143128558.0RepeatNote=LRR 4
TgeneCNOT6chr5:134688635chr5:179991488ENST0000039335651452_73128558.0RepeatNote=LRR 1
TgeneCNOT6chr5:134688635chr5:179991488ENST0000039335651475_96128558.0RepeatNote=LRR 2
TgeneCNOT6chr5:134688635chr5:179991488ENST0000039335651498_120128558.0RepeatNote=LRR 3
TgeneCNOT6chr5:134688636chr5:179991489ENST00000261951312121_143128558.0RepeatNote=LRR 4
TgeneCNOT6chr5:134688636chr5:179991489ENST0000026195131252_73128558.0RepeatNote=LRR 1
TgeneCNOT6chr5:134688636chr5:179991489ENST0000026195131275_96128558.0RepeatNote=LRR 2
TgeneCNOT6chr5:134688636chr5:179991489ENST0000026195131298_120128558.0RepeatNote=LRR 3
TgeneCNOT6chr5:134688636chr5:179991489ENST00000393356514121_143128558.0RepeatNote=LRR 4
TgeneCNOT6chr5:134688636chr5:179991489ENST0000039335651452_73128558.0RepeatNote=LRR 1
TgeneCNOT6chr5:134688636chr5:179991489ENST0000039335651475_96128558.0RepeatNote=LRR 2
TgeneCNOT6chr5:134688636chr5:179991489ENST0000039335651498_120128558.0RepeatNote=LRR 3


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Fusion Gene Sequence for H2AFY-CNOT6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>35491_35491_1_H2AFY-CNOT6_H2AFY_chr5_134688635_ENST00000510038_CNOT6_chr5_179991488_ENST00000261951_length(transcript)=6262nt_BP=820nt
GTCTACATTAGTAATTCCCAACTTGGGTCCGAAAGTGAACTTTTGCTGAAGCGAAGTAGCTAACCGCTTCCATGTGCAAGGCAGGTTCCA
GACTTCGGGTGTGCTCACTGATCCGCCTCCAGGGCCACCGCCATGTCGAGCCGCGGTGGGAAGAAGAAGTCCACCAAGACGTCCAGGTCT
GCCAAAGCAGGAGTCATCTTTCCCGTGGGGCGGATGCTGCGGTACATCAAGAAAGGCCACCCCAAGTACAGGATTGGAGTGGGGGCACCC
GTGTACATGGCCGCCGTCCTGGAATACCTGACAGCGGAGATTCTGGAGCTGGCTGGCAATGCAGCGAGAGACAACAAGAAGGGACGGGTC
ACACCCCGGCACATCCTGCTGGCTGTGGCCAATGATGAAGAGCTGAATCAGCTGCTAAAAGGAGTCACCATAGCCAGTGGGGGTGTGTTA
CCCAACATCCACCCCGAGTTGCTAGCGAAGAAGCGGGGATCCAAAGGAAAGTTGGAAGCCATCATCACACCACCCCCAGCCAAAAAGGCC
AAGTCTCCATCCCAGAAGAAGCCTGTATCTAAAAAAGCAGGAGGCAAGAAAGGGGCCCGGAAATCCAAGAAGAAGCAGGGTGAAGTCAGT
AAGGCAGCCAGCGCCGACAGCACAACCGAGGGCACACCTGCCGACGGCTTCACAGTCCTCTCCACCAAGAGCCTCTTCCTTGGCCAGAAG
CTGAACCTTATTCACAGTGAAATCAGTAATTTAGCCGGCTTTGAGGTGGAGGCCATAATCAATCCTACCAATGCTGACATTGACCTTAAA
GATGACCTAGGAAATCCCCTTACCCAGGATATATTGAACCTTTATCAGGAACCAGATGGAACAAGACGGCTGCTGAACTATTTGCTTGAT
AATTTGTCAGGTACTGCAAAAAGAATTACAACAGAACAACCACCTCCAAGGTCTTGGATTATGTTACAAGAACCAGATAGGACAAGGCCA
ACTGCCTTGTTTTCTGTCATGTGCTATAATGTTCTTTGTGATAAATATGCGACCCGGCAGTTATACGGCTACTGTCCATCATGGGCGCTA
AACTGGGACTACAGGAAAAAGGCCATTATTCAAGAAATCTTGAGCTGCAATGCTGATATCGTAAGTCTTCAGGAGGTTGAAACGGAACAG
TATTACAGTTTTTTTCTGGTAGAGCTGAAAGAACGTGGCTATAATGGATTCTTCAGTCCTAAGTCTAGAGCTAGGACAATGTCAGAACAA
GAAAGGAAACATGTTGATGGCTGTGCAATATTCTTCAAGACAGAAAAATTTACTTTGGTTCAGAAACACACTGTTGAATTTAATCAGCTA
GCCATGGCAAATTCTGAGGGGTCTGAAGCTATGCTGAACAGAGTCATGACAAAAGATAACATTGGGGTTGCAGTACTGCTAGAACTTCGG
AAGGAATCGATTGAAATGCCGTCCGGAAAGCCACATCTTGGAACAGAAAAACAACTTATTCTTGTGGCTAACGCCCACATGCATTGGGAC
CCTGAATACTCTGATGTGAAGTTGGTACAAACTATGATGTTCCTCTCAGAAGTGAAGAACATTATTGATAAAGCCTCTCGCAACCTCAAA
TCCAGTGTTTTGGGAGAATTTGGAACTATTCCACTTGTGTTATGTGCAGATCTTAATTCTTTGCCAGACTCTGGTGTTGTAGAATATTTG
AGCACAGGTGGAGTAGAAACAAATCACAAAGACTTTAAGGAGTTGAGGTATAATGAAAGTCTCACAAACTTCAGCTGTCATGGGAAGAAT
GGAACCACCAATGGAAGGATCACTCATGGTTTCAAGTTACAGAGTGCCTATGAGAGTGGCCTGATGCCTTACACGAATTACACATTTGAT
TTCAAGGGTATAATAGACTACATTTTCTATTCTAAACCTCAGCTGAACACCTTAGGCATCCTGGGCCCTCTGGACCACCACTGGCTGGTT
GAGAATAACATCAGTGGCTGCCCGCACCCCCTCATCCCCTCTGACCACTTCTCACTTTTTGCACAACTGGAGCTCTTACTGCCTTTCCTG
CCCCAAGTCAACGGCATCCACCTTCCTGGCAGGAGGTAGTCAAGCACCTTCAGAGGACAGCCTTGATTCACTTGTAAACTTGTGAAAATC
TGAACATAGGGGAGTGAGGTATGGCCACTGAGGATTTTTGCTTGCTTAAGAATGATTTGGACTTTCAATCTGATTATTTGATAAGGATAT
AGTATGAAAGCCAGGTGCTAGCAACAGACAAATTCTGAGCCCAATATGCTTTATACTGCTAGACAGGGATTGGTGTGTTTGCACCTGTCT
TTCATTTGTCATAAGAGATTTTCCTATTTCTTCTACCCAATAGAATATTTTCATGCCTGGAAATAGGAAAATGTGTGAACAGCGTATTCT
CTTCACACAGAAATCTGTAGCACTGCTTTTTTGAGGCCAGTAGCAACATCCAGAGATCATTCTTCCATACTTTACTCCCTCCTTTTTCAG
ACTTGTTTGTAAAGTACAGAATCTGAATTTAGCCTTTATGATTGTATATGATCCACAGAAGACCTGATTTATGAAATTTTGTACTAAAAT
CATTTGGAAATGATTGTATTGTAAACTGAGGCTAAATTTTTTTTTAAACCTGTTTCATGTGTTATAAAGGCCAGCTTGTAAAAGAAGCTG
CAACAGACTTTCTCTGCTCATGATTTGCACTCTTAGGGTTTTGTTAGCCCTTTTGTACTACTTTCTTTTTAAATTGAGAACATGGTTCTT
TACATATAAATCTGCTTCAACCTTAGGATGTTTTCAGACCAGAGGCAACTTATTCATGAATTTTTATGAAAACTATCTACTAGGACAGAT
AAGCTGAACAGTGATGATCTGTAGACATTTATGGACTGAATGTAATGGTTGATATATGTACATTCTGATATTTTTAAATCTTTAACTTTT
TAAAGTTAAAAACCTACAGCTGCTTAGGTCCAGCTTCTTAACTCTTTTTGAGACACTTCCTGTCCTATCTCCACTGTGCCTGCCTAAATT
TGTTCTCACCAAGCACTGCCTGTGCATGCAGAGAAAATCTGTGCATCCTCTTTTATATTTTTAAAATACTGTTTAACATTTGTGAGAATT
TTATGAAAATGCTTTTGTATGAGCTGTGGCTTTTTCCCATTGTGAAGCATTGAATATCACATTTTGGAACATGTTATAGGGTGAGTCCCT
GGATCTTTGCTCACCAGATCCAAGCACTGCTTCTCGGTGTCATTGCAGTGTGCTGCTTGTCACCCAGAATACTACTATCATGTGAATTCT
TTTTGTCGTCAGTGTCTTTTCCTTAGTCTTTTTGTTGTTGTTGTTGTTGTTGTTTTAATCATTCCTTTTTTAAGAAGAAGTAATTTTCCA
TTTATGAAGCAGTATGAATTAGATGTATTTTCAAAACAGGTCCCTAAGACAATTCTTCAGATCATTTTTAAAATGACTAAGTCATTTTAG
TATGTCAAGCAAGATAAAAATTACATCATACCGTCTATTTTGCCCATAGTGCCATTTAGAGATGAAAACCAGCTTTAACTTTGCAAAGTG
AACATGTACATGGTCTGCTCTCATTTATTCATTCTTCTCTCAAAAGTCAAATGAATGCAGAGGGAGCTTGGTCAAACTGCTTTTGTTTCA
ACTGCAGGCAGGGGAGCAAAAGGACGCCATGTGAGCATTAGGAAAAAAAATACTCACTCTTACTAACAATTTTTATACAGAAAATGAGTC
ATTTTGGAAATGATTCTTATGTTTTTTTTTTTTCTCCTTTTAGAAAATTCTCCAAAAGGTTTTGATGTTGAATCTTGGTCTTGGACCTGT
TTTTTCCTTTGAGGGTTTTTTGTTTTTTGTTTTTTCTAGGATTTCATTGTGATGTTTTGGTTTTGTTTTTTGCTTTTTGTTTAAGTTGTG
CTGACACCAAACACATCCAGTTTATAATCAGTACATTGGAAAGCTGGTATTGATGTAGAACCAGTGCATAACTTTTTATGGGGTTTTGTT
ATTGGTTTTTTTTTGTAAAGTGTGAATAAAAGGTATGTTTACTCATTTTTCCTGAACACTGTGTTGGTAATGTGCATCATGACAATTTCC
AGTGAAGGTGAGCTGGAGCTGGTTGGACTAATGAGACTGAGGAAGCAGCTTTTCCTACGATCTGCATTATGTAATCACAGGTCCAGAGAG
CTTTATGGAAGCGGGAGAGGAGGAGCACTTACTCATGTTGTATTTGTTAATGGAGGATGTCATCTTTTCATAGATGCTGGAACTAGAGTG
CACTTGTTAGATGCTAAAGGTTTGAGCTTTACACAAAATGTCTTCATCTGTATTTGTTATTGTCTACAATATATTTGAATTTGGGGCAGC
ATATTAAGATGTAATGGCCTGTTATGTCTTGAAAATACTTGTTTTGCCTCTTCCAGGCATACTGCATTCTGTGGATCAGTTTGAACAGCT
TCTCCACCTTATTTGGACAGTGATAAATTGAACCAAGAGTGTAGATTTACAAGTGTAACCTTCAAAAGAGGAAGAACTATTTGGGGTCTG
TAGGTAATGAACAGTCACACCAAAATAGACTATGATGCTTTTGTTAAGAAAGGTTTCATGTTTTAGATATTTTCCGTGTCCTAAATAATT
TTCAATAATCTATAATCCCTAAAATGCAATAAAAACTAGTATGTTTTCACGGTGTATATTTTTTTTCAAAAATTCTGTAACAAATATATT
TAATGTGTTGCCATAATGTCATTTCAGTATTTTTGCTGGATAAATCCATTTTAGAAATGTCTTACAAAAAGTTTAGGGCATGTTTTCTGT
TTTAAAGACCAGAAGTTTGAAGGCACCCAAATCCTTGTCGCCAATCTCCTGAAGTACAGCTTTACCATATTAGTGGTCATTATTTATGCT
TTGAGAGTTTCAATATTGTTCGTCAAGTTAACTTATGGCATAATTTAAGCTAAAGTTGTAGAAATGAATTGTTGAGTGCAACTTTCATAG
TCCCAAAGATAGGCAGAGAACATCTCCAGAAATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTAATATGATTTAGTGACAACCAGG
AAAACTTACTTGGGATTATTAGCACTTTCAAACTTAGGGACATTATTAAATTGGATGGAATGCACTTCTAAATGTTTAAATTAAAATTTC
AAAGCTCTTTCGAGATTCAGGTTCTCAATAATAATATTCAAGTTTTAGAGTTTCACTTTGTACTATTTAAATTTATGGAACTAGTTTCCA
TACTGACTTGTAAGGTTTTGGGGTCATATATAAGGACTAAAGCCAAGCTAGGCAAAACAATGACAGCACCGTTTTTTCAGTGAAGCTCTC
AGAATGTCCAGTACAGATGTTGCAGATAATTCCAAGAACTCCTTCAGCAGGTGTTCTTCACCATTCGTAAACAGTATTTTAAGATGTTCA
CTTTGCTCTTCTTTTTGGTTACATACATTTTAATAACTGGTATGTTGAAGTAGTGTCTAAAAGTATCTAGTCTTTATTCACAGTACATTA
TATTGTGTGATGCACTGGACTAACTCTTGTTTACCATTCATGTAACAAAACCCAGCACATTATCTGCACTATAAGCTCAAAGAATGTCAC
ATCCGCCCAGACAGCTCTTTGATGAGGGTGATGGGAACTGAATAAACCATACGGACTGGCAGTAACAAGGGCTTTTACTGTTCTGTTCAG
TGGAACCTTCTTGGTCAAATTGTAATTAGCTAGCATTATATTTATATACAGGGTCTTTTTTCTTTACCGATGTATTTTCCTACTCATAGC
CAACCAATAAATTCAGTATCTGTTTCAAATATTTTAGAAGTGTAGTTTGTATAGCTGTAGTACTGAGGTTTGAGGAAAAATAAATGTTGA
TCAGCAGACCACGTATTTAAAATTCTGAATCTTCTGGGACAGGGTTGTAACTCAGCCTTCCAAAGGGAAGAGTGCAGGGGGACGGGGCCA
TGATATGGGGAAATGGTGTAAACTAATGTATTTCTTTATTGGCTGTTATTCTGTATAACACTCATATCTTTGCCAAAGTTCAATTTTATA
TTTAGGCAACTGATGGTCCTTTTGCATTTAGGATTTTCGTTGTTGTTACCTTATACCTCATGATATAAGGAATGGGCTCATGTGTCTTCC

>35491_35491_1_H2AFY-CNOT6_H2AFY_chr5_134688635_ENST00000510038_CNOT6_chr5_179991488_ENST00000261951_length(amino acids)=658AA_BP=229
MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEE
LNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPA
DGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQP
PPRSWIMLQEPDRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQEVETEQYYSFFLVELKERGY
NGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLG
TEKQLILVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSGVVEYLSTGGVETNHKDFKE
LRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYTNYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPS

--------------------------------------------------------------
>35491_35491_2_H2AFY-CNOT6_H2AFY_chr5_134688635_ENST00000510038_CNOT6_chr5_179991488_ENST00000393356_length(transcript)=6314nt_BP=820nt
GTCTACATTAGTAATTCCCAACTTGGGTCCGAAAGTGAACTTTTGCTGAAGCGAAGTAGCTAACCGCTTCCATGTGCAAGGCAGGTTCCA
GACTTCGGGTGTGCTCACTGATCCGCCTCCAGGGCCACCGCCATGTCGAGCCGCGGTGGGAAGAAGAAGTCCACCAAGACGTCCAGGTCT
GCCAAAGCAGGAGTCATCTTTCCCGTGGGGCGGATGCTGCGGTACATCAAGAAAGGCCACCCCAAGTACAGGATTGGAGTGGGGGCACCC
GTGTACATGGCCGCCGTCCTGGAATACCTGACAGCGGAGATTCTGGAGCTGGCTGGCAATGCAGCGAGAGACAACAAGAAGGGACGGGTC
ACACCCCGGCACATCCTGCTGGCTGTGGCCAATGATGAAGAGCTGAATCAGCTGCTAAAAGGAGTCACCATAGCCAGTGGGGGTGTGTTA
CCCAACATCCACCCCGAGTTGCTAGCGAAGAAGCGGGGATCCAAAGGAAAGTTGGAAGCCATCATCACACCACCCCCAGCCAAAAAGGCC
AAGTCTCCATCCCAGAAGAAGCCTGTATCTAAAAAAGCAGGAGGCAAGAAAGGGGCCCGGAAATCCAAGAAGAAGCAGGGTGAAGTCAGT
AAGGCAGCCAGCGCCGACAGCACAACCGAGGGCACACCTGCCGACGGCTTCACAGTCCTCTCCACCAAGAGCCTCTTCCTTGGCCAGAAG
CTGAACCTTATTCACAGTGAAATCAGTAATTTAGCCGGCTTTGAGGTGGAGGCCATAATCAATCCTACCAATGCTGACATTGACCTTAAA
GATGACCTAGGAAATCCCCTTACCCAGGATATATTGAACCTTTATCAGGAACCAGATGGAACAAGACGGCTGCTGAACTATTTGCTTGAT
AATTTGTCAGGTACTGCAAAAAGAATTACAACAGAACAACCACCTCCAAGGTCTTGGATTATGTTACAAGAACCAGATAGGACAAGGCCA
ACTGCCTTGTTTTCTGTCATGTGCTATAATGTTCTTTGTGATAAATATGCGACCCGGCAGTTATACGGCTACTGTCCATCATGGGCGCTA
AACTGGGACTACAGGAAAAAGGCCATTATTCAAGAAATCTTGAGCTGCAATGCTGATATCGTAAGTCTTCAGGAGGTTGAAACGGAACAG
TATTACAGTTTTTTTCTGGTAGAGCTGAAAGAACGTGGCTATAATGGATTCTTCAGTCCTAAGTCTAGAGCTAGGACAATGTCAGAACAA
GAAAGGAAACATGTTGATGGCTGTGCAATATTCTTCAAGACAGAAAAATTTACTTTGGTTCAGAAACACACTGTTGAATTTAATCAGCTA
GCCATGGCAAATTCTGAGGGGTCTGAAGCTATGCTGAACAGAGTCATGACAAAAGATAACATTGGGGTTGCAGTACTGCTAGAACTTCGG
AAGGAATCGATTGAAATGCCGTCCGGAAAGCCACATCTTGGAACAGAAAAACAACTTATTCTTGTGGCTAACGCCCACATGCATTGGGAC
CCTGAATACTCTGATGTGAAGTTGGTACAAACTATGATGTTCCTCTCAGAAGTGAAGAACATTATTGATAAAGCCTCTCGCAACCTCAAA
TCCAGTGTTTTGGGAGAATTTGGAACTATTCCACTTGTGTTATGTGCAGATCTTAATTCTTTGCCAGACTCTGGTGTTGTAGAATATTTG
AGCACAGGTGGAGTAGAAACAAATCACAAAGACTTTAAGGAGTTGAGGTATAATGAAAGTCTCACAAACTTCAGCTGTCATGGGAAGAAT
GGAACCACCAATGGAAGGATCACTCATGGTTTCAAGTTACAGAGTGCCTATGAGAGTGGCCTGATGCCTTACACGAATTACACATTTGAT
TTCAAGGGTATAATAGACTACATTTTCTATTCTAAACCTCAGCTGAACACCTTAGGCATCCTGGGCCCTCTGGACCACCACTGGCTGGTT
GAGAATAACATCAGTGGCTGCCCGCACCCCCTCATCCCCTCTGACCACTTCTCACTTTTTGCACAACTGGAGCTCTTACTGCCTTTCCTG
CCCCAAGTCAACGGCATCCACCTTCCTGGCAGGAGGTAGTCAAGCACCTTCAGAGGACAGCCTTGATTCACTTGTAAACTTGTGAAAATC
TGAACATAGGGGAGTGAGGTATGGCCACTGAGGATTTTTGCTTGCTTAAGAATGATTTGGACTTTCAATCTGATTATTTGATAAGGATAT
AGTATGAAAGCCAGGTGCTAGCAACAGACAAATTCTGAGCCCAATATGCTTTATACTGCTAGACAGGGATTGGTGTGTTTGCACCTGTCT
TTCATTTGTCATAAGAGATTTTCCTATTTCTTCTACCCAATAGAATATTTTCATGCCTGGAAATAGGAAAATGTGTGAACAGCGTATTCT
CTTCACACAGAAATCTGTAGCACTGCTTTTTTGAGGCCAGTAGCAACATCCAGAGATCATTCTTCCATACTTTACTCCCTCCTTTTTCAG
ACTTGTTTGTAAAGTACAGAATCTGAATTTAGCCTTTATGATTGTATATGATCCACAGAAGACCTGATTTATGAAATTTTGTACTAAAAT
CATTTGGAAATGATTGTATTGTAAACTGAGGCTAAATTTTTTTTTAAACCTGTTTCATGTGTTATAAAGGCCAGCTTGTAAAAGAAGCTG
CAACAGACTTTCTCTGCTCATGATTTGCACTCTTAGGGTTTTGTTAGCCCTTTTGTACTACTTTCTTTTTAAATTGAGAACATGGTTCTT
TACATATAAATCTGCTTCAACCTTAGGATGTTTTCAGACCAGAGGCAACTTATTCATGAATTTTTATGAAAACTATCTACTAGGACAGAT
AAGCTGAACAGTGATGATCTGTAGACATTTATGGACTGAATGTAATGGTTGATATATGTACATTCTGATATTTTTAAATCTTTAACTTTT
TAAAGTTAAAAACCTACAGCTGCTTAGGTCCAGCTTCTTAACTCTTTTTGAGACACTTCCTGTCCTATCTCCACTGTGCCTGCCTAAATT
TGTTCTCACCAAGCACTGCCTGTGCATGCAGAGAAAATCTGTGCATCCTCTTTTATATTTTTAAAATACTGTTTAACATTTGTGAGAATT
TTATGAAAATGCTTTTGTATGAGCTGTGGCTTTTTCCCATTGTGAAGCATTGAATATCACATTTTGGAACATGTTATAGGGTGAGTCCCT
GGATCTTTGCTCACCAGATCCAAGCACTGCTTCTCGGTGTCATTGCAGTGTGCTGCTTGTCACCCAGAATACTACTATCATGTGAATTCT
TTTTGTCGTCAGTGTCTTTTCCTTAGTCTTTTTGTTGTTGTTGTTGTTGTTGTTTTAATCATTCCTTTTTTAAGAAGAAGTAATTTTCCA
TTTATGAAGCAGTATGAATTAGATGTATTTTCAAAACAGGTCCCTAAGACAATTCTTCAGATCATTTTTAAAATGACTAAGTCATTTTAG
TATGTCAAGCAAGATAAAAATTACATCATACCGTCTATTTTGCCCATAGTGCCATTTAGAGATGAAAACCAGCTTTAACTTTGCAAAGTG
AACATGTACATGGTCTGCTCTCATTTATTCATTCTTCTCTCAAAAGTCAAATGAATGCAGAGGGAGCTTGGTCAAACTGCTTTTGTTTCA
ACTGCAGGCAGGGGAGCAAAAGGACGCCATGTGAGCATTAGGAAAAAAAATACTCACTCTTACTAACAATTTTTATACAGAAAATGAGTC
ATTTTGGAAATGATTCTTATGTTTTTTTTTTTTCTCCTTTTAGAAAATTCTCCAAAAGGTTTTGATGTTGAATCTTGGTCTTGGACCTGT
TTTTTCCTTTGAGGGTTTTTTGTTTTTTGTTTTTTCTAGGATTTCATTGTGATGTTTTGGTTTTGTTTTTTGCTTTTTGTTTAAGTTGTG
CTGACACCAAACACATCCAGTTTATAATCAGTACATTGGAAAGCTGGTATTGATGTAGAACCAGTGCATAACTTTTTATGGGGTTTTGTT
ATTGGTTTTTTTTTGTAAAGTGTGAATAAAAGGTATGTTTACTCATTTTTCCTGAACACTGTGTTGGTAATGTGCATCATGACAATTTCC
AGTGAAGGTGAGCTGGAGCTGGTTGGACTAATGAGACTGAGGAAGCAGCTTTTCCTACGATCTGCATTATGTAATCACAGGTCCAGAGAG
CTTTATGGAAGCGGGAGAGGAGGAGCACTTACTCATGTTGTATTTGTTAATGGAGGATGTCATCTTTTCATAGATGCTGGAACTAGAGTG
CACTTGTTAGATGCTAAAGGTTTGAGCTTTACACAAAATGTCTTCATCTGTATTTGTTATTGTCTACAATATATTTGAATTTGGGGCAGC
ATATTAAGATGTAATGGCCTGTTATGTCTTGAAAATACTTGTTTTGCCTCTTCCAGGCATACTGCATTCTGTGGATCAGTTTGAACAGCT
TCTCCACCTTATTTGGACAGTGATAAATTGAACCAAGAGTGTAGATTTACAAGTGTAACCTTCAAAAGAGGAAGAACTATTTGGGGTCTG
TAGGTAATGAACAGTCACACCAAAATAGACTATGATGCTTTTGTTAAGAAAGGTTTCATGTTTTAGATATTTTCCGTGTCCTAAATAATT
TTCAATAATCTATAATCCCTAAAATGCAATAAAAACTAGTATGTTTTCACGGTGTATATTTTTTTTCAAAAATTCTGTAACAAATATATT
TAATGTGTTGCCATAATGTCATTTCAGTATTTTTGCTGGATAAATCCATTTTAGAAATGTCTTACAAAAAGTTTAGGGCATGTTTTCTGT
TTTAAAGACCAGAAGTTTGAAGGCACCCAAATCCTTGTCGCCAATCTCCTGAAGTACAGCTTTACCATATTAGTGGTCATTATTTATGCT
TTGAGAGTTTCAATATTGTTCGTCAAGTTAACTTATGGCATAATTTAAGCTAAAGTTGTAGAAATGAATTGTTGAGTGCAACTTTCATAG
TCCCAAAGATAGGCAGAGAACATCTCCAGAAATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTAATATGATTTAGTGACAACCAGG
AAAACTTACTTGGGATTATTAGCACTTTCAAACTTAGGGACATTATTAAATTGGATGGAATGCACTTCTAAATGTTTAAATTAAAATTTC
AAAGCTCTTTCGAGATTCAGGTTCTCAATAATAATATTCAAGTTTTAGAGTTTCACTTTGTACTATTTAAATTTATGGAACTAGTTTCCA
TACTGACTTGTAAGGTTTTGGGGTCATATATAAGGACTAAAGCCAAGCTAGGCAAAACAATGACAGCACCGTTTTTTCAGTGAAGCTCTC
AGAATGTCCAGTACAGATGTTGCAGATAATTCCAAGAACTCCTTCAGCAGGTGTTCTTCACCATTCGTAAACAGTATTTTAAGATGTTCA
CTTTGCTCTTCTTTTTGGTTACATACATTTTAATAACTGGTATGTTGAAGTAGTGTCTAAAAGTATCTAGTCTTTATTCACAGTACATTA
TATTGTGTGATGCACTGGACTAACTCTTGTTTACCATTCATGTAACAAAACCCAGCACATTATCTGCACTATAAGCTCAAAGAATGTCAC
ATCCGCCCAGACAGCTCTTTGATGAGGGTGATGGGAACTGAATAAACCATACGGACTGGCAGTAACAAGGGCTTTTACTGTTCTGTTCAG
TGGAACCTTCTTGGTCAAATTGTAATTAGCTAGCATTATATTTATATACAGGGTCTTTTTTCTTTACCGATGTATTTTCCTACTCATAGC
CAACCAATAAATTCAGTATCTGTTTCAAATATTTTAGAAGTGTAGTTTGTATAGCTGTAGTACTGAGGTTTGAGGAAAAATAAATGTTGA
TCAGCAGACCACGTATTTAAAATTCTGAATCTTCTGGGACAGGGTTGTAACTCAGCCTTCCAAAGGGAAGAGTGCAGGGGGACGGGGCCA
TGATATGGGGAAATGGTGTAAACTAATGTATTTCTTTATTGGCTGTTATTCTGTATAACACTCATATCTTTGCCAAAGTTCAATTTTATA
TTTAGGCAACTGATGGTCCTTTTGCATTTAGGATTTTCGTTGTTGTTACCTTATACCTCATGATATAAGGAATGGGCTCATGTGTCTTCC
GTCTTTTGGAAGGAGGTTGACATATTTTAAATAAATGCTTTTAAATACAGTAGCAAACATTGTGTTGGGGTTATAATAATTCATTAAATG

>35491_35491_2_H2AFY-CNOT6_H2AFY_chr5_134688635_ENST00000510038_CNOT6_chr5_179991488_ENST00000393356_length(amino acids)=658AA_BP=229
MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEE
LNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPA
DGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQP
PPRSWIMLQEPDRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQEVETEQYYSFFLVELKERGY
NGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLG
TEKQLILVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSGVVEYLSTGGVETNHKDFKE
LRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYTNYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPS

--------------------------------------------------------------
>35491_35491_3_H2AFY-CNOT6_H2AFY_chr5_134688636_ENST00000510038_CNOT6_chr5_179991489_ENST00000261951_length(transcript)=6262nt_BP=820nt
GTCTACATTAGTAATTCCCAACTTGGGTCCGAAAGTGAACTTTTGCTGAAGCGAAGTAGCTAACCGCTTCCATGTGCAAGGCAGGTTCCA
GACTTCGGGTGTGCTCACTGATCCGCCTCCAGGGCCACCGCCATGTCGAGCCGCGGTGGGAAGAAGAAGTCCACCAAGACGTCCAGGTCT
GCCAAAGCAGGAGTCATCTTTCCCGTGGGGCGGATGCTGCGGTACATCAAGAAAGGCCACCCCAAGTACAGGATTGGAGTGGGGGCACCC
GTGTACATGGCCGCCGTCCTGGAATACCTGACAGCGGAGATTCTGGAGCTGGCTGGCAATGCAGCGAGAGACAACAAGAAGGGACGGGTC
ACACCCCGGCACATCCTGCTGGCTGTGGCCAATGATGAAGAGCTGAATCAGCTGCTAAAAGGAGTCACCATAGCCAGTGGGGGTGTGTTA
CCCAACATCCACCCCGAGTTGCTAGCGAAGAAGCGGGGATCCAAAGGAAAGTTGGAAGCCATCATCACACCACCCCCAGCCAAAAAGGCC
AAGTCTCCATCCCAGAAGAAGCCTGTATCTAAAAAAGCAGGAGGCAAGAAAGGGGCCCGGAAATCCAAGAAGAAGCAGGGTGAAGTCAGT
AAGGCAGCCAGCGCCGACAGCACAACCGAGGGCACACCTGCCGACGGCTTCACAGTCCTCTCCACCAAGAGCCTCTTCCTTGGCCAGAAG
CTGAACCTTATTCACAGTGAAATCAGTAATTTAGCCGGCTTTGAGGTGGAGGCCATAATCAATCCTACCAATGCTGACATTGACCTTAAA
GATGACCTAGGAAATCCCCTTACCCAGGATATATTGAACCTTTATCAGGAACCAGATGGAACAAGACGGCTGCTGAACTATTTGCTTGAT
AATTTGTCAGGTACTGCAAAAAGAATTACAACAGAACAACCACCTCCAAGGTCTTGGATTATGTTACAAGAACCAGATAGGACAAGGCCA
ACTGCCTTGTTTTCTGTCATGTGCTATAATGTTCTTTGTGATAAATATGCGACCCGGCAGTTATACGGCTACTGTCCATCATGGGCGCTA
AACTGGGACTACAGGAAAAAGGCCATTATTCAAGAAATCTTGAGCTGCAATGCTGATATCGTAAGTCTTCAGGAGGTTGAAACGGAACAG
TATTACAGTTTTTTTCTGGTAGAGCTGAAAGAACGTGGCTATAATGGATTCTTCAGTCCTAAGTCTAGAGCTAGGACAATGTCAGAACAA
GAAAGGAAACATGTTGATGGCTGTGCAATATTCTTCAAGACAGAAAAATTTACTTTGGTTCAGAAACACACTGTTGAATTTAATCAGCTA
GCCATGGCAAATTCTGAGGGGTCTGAAGCTATGCTGAACAGAGTCATGACAAAAGATAACATTGGGGTTGCAGTACTGCTAGAACTTCGG
AAGGAATCGATTGAAATGCCGTCCGGAAAGCCACATCTTGGAACAGAAAAACAACTTATTCTTGTGGCTAACGCCCACATGCATTGGGAC
CCTGAATACTCTGATGTGAAGTTGGTACAAACTATGATGTTCCTCTCAGAAGTGAAGAACATTATTGATAAAGCCTCTCGCAACCTCAAA
TCCAGTGTTTTGGGAGAATTTGGAACTATTCCACTTGTGTTATGTGCAGATCTTAATTCTTTGCCAGACTCTGGTGTTGTAGAATATTTG
AGCACAGGTGGAGTAGAAACAAATCACAAAGACTTTAAGGAGTTGAGGTATAATGAAAGTCTCACAAACTTCAGCTGTCATGGGAAGAAT
GGAACCACCAATGGAAGGATCACTCATGGTTTCAAGTTACAGAGTGCCTATGAGAGTGGCCTGATGCCTTACACGAATTACACATTTGAT
TTCAAGGGTATAATAGACTACATTTTCTATTCTAAACCTCAGCTGAACACCTTAGGCATCCTGGGCCCTCTGGACCACCACTGGCTGGTT
GAGAATAACATCAGTGGCTGCCCGCACCCCCTCATCCCCTCTGACCACTTCTCACTTTTTGCACAACTGGAGCTCTTACTGCCTTTCCTG
CCCCAAGTCAACGGCATCCACCTTCCTGGCAGGAGGTAGTCAAGCACCTTCAGAGGACAGCCTTGATTCACTTGTAAACTTGTGAAAATC
TGAACATAGGGGAGTGAGGTATGGCCACTGAGGATTTTTGCTTGCTTAAGAATGATTTGGACTTTCAATCTGATTATTTGATAAGGATAT
AGTATGAAAGCCAGGTGCTAGCAACAGACAAATTCTGAGCCCAATATGCTTTATACTGCTAGACAGGGATTGGTGTGTTTGCACCTGTCT
TTCATTTGTCATAAGAGATTTTCCTATTTCTTCTACCCAATAGAATATTTTCATGCCTGGAAATAGGAAAATGTGTGAACAGCGTATTCT
CTTCACACAGAAATCTGTAGCACTGCTTTTTTGAGGCCAGTAGCAACATCCAGAGATCATTCTTCCATACTTTACTCCCTCCTTTTTCAG
ACTTGTTTGTAAAGTACAGAATCTGAATTTAGCCTTTATGATTGTATATGATCCACAGAAGACCTGATTTATGAAATTTTGTACTAAAAT
CATTTGGAAATGATTGTATTGTAAACTGAGGCTAAATTTTTTTTTAAACCTGTTTCATGTGTTATAAAGGCCAGCTTGTAAAAGAAGCTG
CAACAGACTTTCTCTGCTCATGATTTGCACTCTTAGGGTTTTGTTAGCCCTTTTGTACTACTTTCTTTTTAAATTGAGAACATGGTTCTT
TACATATAAATCTGCTTCAACCTTAGGATGTTTTCAGACCAGAGGCAACTTATTCATGAATTTTTATGAAAACTATCTACTAGGACAGAT
AAGCTGAACAGTGATGATCTGTAGACATTTATGGACTGAATGTAATGGTTGATATATGTACATTCTGATATTTTTAAATCTTTAACTTTT
TAAAGTTAAAAACCTACAGCTGCTTAGGTCCAGCTTCTTAACTCTTTTTGAGACACTTCCTGTCCTATCTCCACTGTGCCTGCCTAAATT
TGTTCTCACCAAGCACTGCCTGTGCATGCAGAGAAAATCTGTGCATCCTCTTTTATATTTTTAAAATACTGTTTAACATTTGTGAGAATT
TTATGAAAATGCTTTTGTATGAGCTGTGGCTTTTTCCCATTGTGAAGCATTGAATATCACATTTTGGAACATGTTATAGGGTGAGTCCCT
GGATCTTTGCTCACCAGATCCAAGCACTGCTTCTCGGTGTCATTGCAGTGTGCTGCTTGTCACCCAGAATACTACTATCATGTGAATTCT
TTTTGTCGTCAGTGTCTTTTCCTTAGTCTTTTTGTTGTTGTTGTTGTTGTTGTTTTAATCATTCCTTTTTTAAGAAGAAGTAATTTTCCA
TTTATGAAGCAGTATGAATTAGATGTATTTTCAAAACAGGTCCCTAAGACAATTCTTCAGATCATTTTTAAAATGACTAAGTCATTTTAG
TATGTCAAGCAAGATAAAAATTACATCATACCGTCTATTTTGCCCATAGTGCCATTTAGAGATGAAAACCAGCTTTAACTTTGCAAAGTG
AACATGTACATGGTCTGCTCTCATTTATTCATTCTTCTCTCAAAAGTCAAATGAATGCAGAGGGAGCTTGGTCAAACTGCTTTTGTTTCA
ACTGCAGGCAGGGGAGCAAAAGGACGCCATGTGAGCATTAGGAAAAAAAATACTCACTCTTACTAACAATTTTTATACAGAAAATGAGTC
ATTTTGGAAATGATTCTTATGTTTTTTTTTTTTCTCCTTTTAGAAAATTCTCCAAAAGGTTTTGATGTTGAATCTTGGTCTTGGACCTGT
TTTTTCCTTTGAGGGTTTTTTGTTTTTTGTTTTTTCTAGGATTTCATTGTGATGTTTTGGTTTTGTTTTTTGCTTTTTGTTTAAGTTGTG
CTGACACCAAACACATCCAGTTTATAATCAGTACATTGGAAAGCTGGTATTGATGTAGAACCAGTGCATAACTTTTTATGGGGTTTTGTT
ATTGGTTTTTTTTTGTAAAGTGTGAATAAAAGGTATGTTTACTCATTTTTCCTGAACACTGTGTTGGTAATGTGCATCATGACAATTTCC
AGTGAAGGTGAGCTGGAGCTGGTTGGACTAATGAGACTGAGGAAGCAGCTTTTCCTACGATCTGCATTATGTAATCACAGGTCCAGAGAG
CTTTATGGAAGCGGGAGAGGAGGAGCACTTACTCATGTTGTATTTGTTAATGGAGGATGTCATCTTTTCATAGATGCTGGAACTAGAGTG
CACTTGTTAGATGCTAAAGGTTTGAGCTTTACACAAAATGTCTTCATCTGTATTTGTTATTGTCTACAATATATTTGAATTTGGGGCAGC
ATATTAAGATGTAATGGCCTGTTATGTCTTGAAAATACTTGTTTTGCCTCTTCCAGGCATACTGCATTCTGTGGATCAGTTTGAACAGCT
TCTCCACCTTATTTGGACAGTGATAAATTGAACCAAGAGTGTAGATTTACAAGTGTAACCTTCAAAAGAGGAAGAACTATTTGGGGTCTG
TAGGTAATGAACAGTCACACCAAAATAGACTATGATGCTTTTGTTAAGAAAGGTTTCATGTTTTAGATATTTTCCGTGTCCTAAATAATT
TTCAATAATCTATAATCCCTAAAATGCAATAAAAACTAGTATGTTTTCACGGTGTATATTTTTTTTCAAAAATTCTGTAACAAATATATT
TAATGTGTTGCCATAATGTCATTTCAGTATTTTTGCTGGATAAATCCATTTTAGAAATGTCTTACAAAAAGTTTAGGGCATGTTTTCTGT
TTTAAAGACCAGAAGTTTGAAGGCACCCAAATCCTTGTCGCCAATCTCCTGAAGTACAGCTTTACCATATTAGTGGTCATTATTTATGCT
TTGAGAGTTTCAATATTGTTCGTCAAGTTAACTTATGGCATAATTTAAGCTAAAGTTGTAGAAATGAATTGTTGAGTGCAACTTTCATAG
TCCCAAAGATAGGCAGAGAACATCTCCAGAAATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTAATATGATTTAGTGACAACCAGG
AAAACTTACTTGGGATTATTAGCACTTTCAAACTTAGGGACATTATTAAATTGGATGGAATGCACTTCTAAATGTTTAAATTAAAATTTC
AAAGCTCTTTCGAGATTCAGGTTCTCAATAATAATATTCAAGTTTTAGAGTTTCACTTTGTACTATTTAAATTTATGGAACTAGTTTCCA
TACTGACTTGTAAGGTTTTGGGGTCATATATAAGGACTAAAGCCAAGCTAGGCAAAACAATGACAGCACCGTTTTTTCAGTGAAGCTCTC
AGAATGTCCAGTACAGATGTTGCAGATAATTCCAAGAACTCCTTCAGCAGGTGTTCTTCACCATTCGTAAACAGTATTTTAAGATGTTCA
CTTTGCTCTTCTTTTTGGTTACATACATTTTAATAACTGGTATGTTGAAGTAGTGTCTAAAAGTATCTAGTCTTTATTCACAGTACATTA
TATTGTGTGATGCACTGGACTAACTCTTGTTTACCATTCATGTAACAAAACCCAGCACATTATCTGCACTATAAGCTCAAAGAATGTCAC
ATCCGCCCAGACAGCTCTTTGATGAGGGTGATGGGAACTGAATAAACCATACGGACTGGCAGTAACAAGGGCTTTTACTGTTCTGTTCAG
TGGAACCTTCTTGGTCAAATTGTAATTAGCTAGCATTATATTTATATACAGGGTCTTTTTTCTTTACCGATGTATTTTCCTACTCATAGC
CAACCAATAAATTCAGTATCTGTTTCAAATATTTTAGAAGTGTAGTTTGTATAGCTGTAGTACTGAGGTTTGAGGAAAAATAAATGTTGA
TCAGCAGACCACGTATTTAAAATTCTGAATCTTCTGGGACAGGGTTGTAACTCAGCCTTCCAAAGGGAAGAGTGCAGGGGGACGGGGCCA
TGATATGGGGAAATGGTGTAAACTAATGTATTTCTTTATTGGCTGTTATTCTGTATAACACTCATATCTTTGCCAAAGTTCAATTTTATA
TTTAGGCAACTGATGGTCCTTTTGCATTTAGGATTTTCGTTGTTGTTACCTTATACCTCATGATATAAGGAATGGGCTCATGTGTCTTCC

>35491_35491_3_H2AFY-CNOT6_H2AFY_chr5_134688636_ENST00000510038_CNOT6_chr5_179991489_ENST00000261951_length(amino acids)=658AA_BP=229
MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEE
LNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPA
DGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQP
PPRSWIMLQEPDRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQEVETEQYYSFFLVELKERGY
NGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLG
TEKQLILVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSGVVEYLSTGGVETNHKDFKE
LRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYTNYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPS

--------------------------------------------------------------
>35491_35491_4_H2AFY-CNOT6_H2AFY_chr5_134688636_ENST00000510038_CNOT6_chr5_179991489_ENST00000393356_length(transcript)=6314nt_BP=820nt
GTCTACATTAGTAATTCCCAACTTGGGTCCGAAAGTGAACTTTTGCTGAAGCGAAGTAGCTAACCGCTTCCATGTGCAAGGCAGGTTCCA
GACTTCGGGTGTGCTCACTGATCCGCCTCCAGGGCCACCGCCATGTCGAGCCGCGGTGGGAAGAAGAAGTCCACCAAGACGTCCAGGTCT
GCCAAAGCAGGAGTCATCTTTCCCGTGGGGCGGATGCTGCGGTACATCAAGAAAGGCCACCCCAAGTACAGGATTGGAGTGGGGGCACCC
GTGTACATGGCCGCCGTCCTGGAATACCTGACAGCGGAGATTCTGGAGCTGGCTGGCAATGCAGCGAGAGACAACAAGAAGGGACGGGTC
ACACCCCGGCACATCCTGCTGGCTGTGGCCAATGATGAAGAGCTGAATCAGCTGCTAAAAGGAGTCACCATAGCCAGTGGGGGTGTGTTA
CCCAACATCCACCCCGAGTTGCTAGCGAAGAAGCGGGGATCCAAAGGAAAGTTGGAAGCCATCATCACACCACCCCCAGCCAAAAAGGCC
AAGTCTCCATCCCAGAAGAAGCCTGTATCTAAAAAAGCAGGAGGCAAGAAAGGGGCCCGGAAATCCAAGAAGAAGCAGGGTGAAGTCAGT
AAGGCAGCCAGCGCCGACAGCACAACCGAGGGCACACCTGCCGACGGCTTCACAGTCCTCTCCACCAAGAGCCTCTTCCTTGGCCAGAAG
CTGAACCTTATTCACAGTGAAATCAGTAATTTAGCCGGCTTTGAGGTGGAGGCCATAATCAATCCTACCAATGCTGACATTGACCTTAAA
GATGACCTAGGAAATCCCCTTACCCAGGATATATTGAACCTTTATCAGGAACCAGATGGAACAAGACGGCTGCTGAACTATTTGCTTGAT
AATTTGTCAGGTACTGCAAAAAGAATTACAACAGAACAACCACCTCCAAGGTCTTGGATTATGTTACAAGAACCAGATAGGACAAGGCCA
ACTGCCTTGTTTTCTGTCATGTGCTATAATGTTCTTTGTGATAAATATGCGACCCGGCAGTTATACGGCTACTGTCCATCATGGGCGCTA
AACTGGGACTACAGGAAAAAGGCCATTATTCAAGAAATCTTGAGCTGCAATGCTGATATCGTAAGTCTTCAGGAGGTTGAAACGGAACAG
TATTACAGTTTTTTTCTGGTAGAGCTGAAAGAACGTGGCTATAATGGATTCTTCAGTCCTAAGTCTAGAGCTAGGACAATGTCAGAACAA
GAAAGGAAACATGTTGATGGCTGTGCAATATTCTTCAAGACAGAAAAATTTACTTTGGTTCAGAAACACACTGTTGAATTTAATCAGCTA
GCCATGGCAAATTCTGAGGGGTCTGAAGCTATGCTGAACAGAGTCATGACAAAAGATAACATTGGGGTTGCAGTACTGCTAGAACTTCGG
AAGGAATCGATTGAAATGCCGTCCGGAAAGCCACATCTTGGAACAGAAAAACAACTTATTCTTGTGGCTAACGCCCACATGCATTGGGAC
CCTGAATACTCTGATGTGAAGTTGGTACAAACTATGATGTTCCTCTCAGAAGTGAAGAACATTATTGATAAAGCCTCTCGCAACCTCAAA
TCCAGTGTTTTGGGAGAATTTGGAACTATTCCACTTGTGTTATGTGCAGATCTTAATTCTTTGCCAGACTCTGGTGTTGTAGAATATTTG
AGCACAGGTGGAGTAGAAACAAATCACAAAGACTTTAAGGAGTTGAGGTATAATGAAAGTCTCACAAACTTCAGCTGTCATGGGAAGAAT
GGAACCACCAATGGAAGGATCACTCATGGTTTCAAGTTACAGAGTGCCTATGAGAGTGGCCTGATGCCTTACACGAATTACACATTTGAT
TTCAAGGGTATAATAGACTACATTTTCTATTCTAAACCTCAGCTGAACACCTTAGGCATCCTGGGCCCTCTGGACCACCACTGGCTGGTT
GAGAATAACATCAGTGGCTGCCCGCACCCCCTCATCCCCTCTGACCACTTCTCACTTTTTGCACAACTGGAGCTCTTACTGCCTTTCCTG
CCCCAAGTCAACGGCATCCACCTTCCTGGCAGGAGGTAGTCAAGCACCTTCAGAGGACAGCCTTGATTCACTTGTAAACTTGTGAAAATC
TGAACATAGGGGAGTGAGGTATGGCCACTGAGGATTTTTGCTTGCTTAAGAATGATTTGGACTTTCAATCTGATTATTTGATAAGGATAT
AGTATGAAAGCCAGGTGCTAGCAACAGACAAATTCTGAGCCCAATATGCTTTATACTGCTAGACAGGGATTGGTGTGTTTGCACCTGTCT
TTCATTTGTCATAAGAGATTTTCCTATTTCTTCTACCCAATAGAATATTTTCATGCCTGGAAATAGGAAAATGTGTGAACAGCGTATTCT
CTTCACACAGAAATCTGTAGCACTGCTTTTTTGAGGCCAGTAGCAACATCCAGAGATCATTCTTCCATACTTTACTCCCTCCTTTTTCAG
ACTTGTTTGTAAAGTACAGAATCTGAATTTAGCCTTTATGATTGTATATGATCCACAGAAGACCTGATTTATGAAATTTTGTACTAAAAT
CATTTGGAAATGATTGTATTGTAAACTGAGGCTAAATTTTTTTTTAAACCTGTTTCATGTGTTATAAAGGCCAGCTTGTAAAAGAAGCTG
CAACAGACTTTCTCTGCTCATGATTTGCACTCTTAGGGTTTTGTTAGCCCTTTTGTACTACTTTCTTTTTAAATTGAGAACATGGTTCTT
TACATATAAATCTGCTTCAACCTTAGGATGTTTTCAGACCAGAGGCAACTTATTCATGAATTTTTATGAAAACTATCTACTAGGACAGAT
AAGCTGAACAGTGATGATCTGTAGACATTTATGGACTGAATGTAATGGTTGATATATGTACATTCTGATATTTTTAAATCTTTAACTTTT
TAAAGTTAAAAACCTACAGCTGCTTAGGTCCAGCTTCTTAACTCTTTTTGAGACACTTCCTGTCCTATCTCCACTGTGCCTGCCTAAATT
TGTTCTCACCAAGCACTGCCTGTGCATGCAGAGAAAATCTGTGCATCCTCTTTTATATTTTTAAAATACTGTTTAACATTTGTGAGAATT
TTATGAAAATGCTTTTGTATGAGCTGTGGCTTTTTCCCATTGTGAAGCATTGAATATCACATTTTGGAACATGTTATAGGGTGAGTCCCT
GGATCTTTGCTCACCAGATCCAAGCACTGCTTCTCGGTGTCATTGCAGTGTGCTGCTTGTCACCCAGAATACTACTATCATGTGAATTCT
TTTTGTCGTCAGTGTCTTTTCCTTAGTCTTTTTGTTGTTGTTGTTGTTGTTGTTTTAATCATTCCTTTTTTAAGAAGAAGTAATTTTCCA
TTTATGAAGCAGTATGAATTAGATGTATTTTCAAAACAGGTCCCTAAGACAATTCTTCAGATCATTTTTAAAATGACTAAGTCATTTTAG
TATGTCAAGCAAGATAAAAATTACATCATACCGTCTATTTTGCCCATAGTGCCATTTAGAGATGAAAACCAGCTTTAACTTTGCAAAGTG
AACATGTACATGGTCTGCTCTCATTTATTCATTCTTCTCTCAAAAGTCAAATGAATGCAGAGGGAGCTTGGTCAAACTGCTTTTGTTTCA
ACTGCAGGCAGGGGAGCAAAAGGACGCCATGTGAGCATTAGGAAAAAAAATACTCACTCTTACTAACAATTTTTATACAGAAAATGAGTC
ATTTTGGAAATGATTCTTATGTTTTTTTTTTTTCTCCTTTTAGAAAATTCTCCAAAAGGTTTTGATGTTGAATCTTGGTCTTGGACCTGT
TTTTTCCTTTGAGGGTTTTTTGTTTTTTGTTTTTTCTAGGATTTCATTGTGATGTTTTGGTTTTGTTTTTTGCTTTTTGTTTAAGTTGTG
CTGACACCAAACACATCCAGTTTATAATCAGTACATTGGAAAGCTGGTATTGATGTAGAACCAGTGCATAACTTTTTATGGGGTTTTGTT
ATTGGTTTTTTTTTGTAAAGTGTGAATAAAAGGTATGTTTACTCATTTTTCCTGAACACTGTGTTGGTAATGTGCATCATGACAATTTCC
AGTGAAGGTGAGCTGGAGCTGGTTGGACTAATGAGACTGAGGAAGCAGCTTTTCCTACGATCTGCATTATGTAATCACAGGTCCAGAGAG
CTTTATGGAAGCGGGAGAGGAGGAGCACTTACTCATGTTGTATTTGTTAATGGAGGATGTCATCTTTTCATAGATGCTGGAACTAGAGTG
CACTTGTTAGATGCTAAAGGTTTGAGCTTTACACAAAATGTCTTCATCTGTATTTGTTATTGTCTACAATATATTTGAATTTGGGGCAGC
ATATTAAGATGTAATGGCCTGTTATGTCTTGAAAATACTTGTTTTGCCTCTTCCAGGCATACTGCATTCTGTGGATCAGTTTGAACAGCT
TCTCCACCTTATTTGGACAGTGATAAATTGAACCAAGAGTGTAGATTTACAAGTGTAACCTTCAAAAGAGGAAGAACTATTTGGGGTCTG
TAGGTAATGAACAGTCACACCAAAATAGACTATGATGCTTTTGTTAAGAAAGGTTTCATGTTTTAGATATTTTCCGTGTCCTAAATAATT
TTCAATAATCTATAATCCCTAAAATGCAATAAAAACTAGTATGTTTTCACGGTGTATATTTTTTTTCAAAAATTCTGTAACAAATATATT
TAATGTGTTGCCATAATGTCATTTCAGTATTTTTGCTGGATAAATCCATTTTAGAAATGTCTTACAAAAAGTTTAGGGCATGTTTTCTGT
TTTAAAGACCAGAAGTTTGAAGGCACCCAAATCCTTGTCGCCAATCTCCTGAAGTACAGCTTTACCATATTAGTGGTCATTATTTATGCT
TTGAGAGTTTCAATATTGTTCGTCAAGTTAACTTATGGCATAATTTAAGCTAAAGTTGTAGAAATGAATTGTTGAGTGCAACTTTCATAG
TCCCAAAGATAGGCAGAGAACATCTCCAGAAATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTAATATGATTTAGTGACAACCAGG
AAAACTTACTTGGGATTATTAGCACTTTCAAACTTAGGGACATTATTAAATTGGATGGAATGCACTTCTAAATGTTTAAATTAAAATTTC
AAAGCTCTTTCGAGATTCAGGTTCTCAATAATAATATTCAAGTTTTAGAGTTTCACTTTGTACTATTTAAATTTATGGAACTAGTTTCCA
TACTGACTTGTAAGGTTTTGGGGTCATATATAAGGACTAAAGCCAAGCTAGGCAAAACAATGACAGCACCGTTTTTTCAGTGAAGCTCTC
AGAATGTCCAGTACAGATGTTGCAGATAATTCCAAGAACTCCTTCAGCAGGTGTTCTTCACCATTCGTAAACAGTATTTTAAGATGTTCA
CTTTGCTCTTCTTTTTGGTTACATACATTTTAATAACTGGTATGTTGAAGTAGTGTCTAAAAGTATCTAGTCTTTATTCACAGTACATTA
TATTGTGTGATGCACTGGACTAACTCTTGTTTACCATTCATGTAACAAAACCCAGCACATTATCTGCACTATAAGCTCAAAGAATGTCAC
ATCCGCCCAGACAGCTCTTTGATGAGGGTGATGGGAACTGAATAAACCATACGGACTGGCAGTAACAAGGGCTTTTACTGTTCTGTTCAG
TGGAACCTTCTTGGTCAAATTGTAATTAGCTAGCATTATATTTATATACAGGGTCTTTTTTCTTTACCGATGTATTTTCCTACTCATAGC
CAACCAATAAATTCAGTATCTGTTTCAAATATTTTAGAAGTGTAGTTTGTATAGCTGTAGTACTGAGGTTTGAGGAAAAATAAATGTTGA
TCAGCAGACCACGTATTTAAAATTCTGAATCTTCTGGGACAGGGTTGTAACTCAGCCTTCCAAAGGGAAGAGTGCAGGGGGACGGGGCCA
TGATATGGGGAAATGGTGTAAACTAATGTATTTCTTTATTGGCTGTTATTCTGTATAACACTCATATCTTTGCCAAAGTTCAATTTTATA
TTTAGGCAACTGATGGTCCTTTTGCATTTAGGATTTTCGTTGTTGTTACCTTATACCTCATGATATAAGGAATGGGCTCATGTGTCTTCC
GTCTTTTGGAAGGAGGTTGACATATTTTAAATAAATGCTTTTAAATACAGTAGCAAACATTGTGTTGGGGTTATAATAATTCATTAAATG

>35491_35491_4_H2AFY-CNOT6_H2AFY_chr5_134688636_ENST00000510038_CNOT6_chr5_179991489_ENST00000393356_length(amino acids)=658AA_BP=229
MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEE
LNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPA
DGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQP
PPRSWIMLQEPDRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQEVETEQYYSFFLVELKERGY
NGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLG
TEKQLILVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSGVVEYLSTGGVETNHKDFKE
LRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYTNYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for H2AFY-CNOT6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for H2AFY-CNOT6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for H2AFY-CNOT6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource