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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:HAVCR1-TIMD4 (FusionGDB2 ID:35669)

Fusion Gene Summary for HAVCR1-TIMD4

check button Fusion gene summary
Fusion gene informationFusion gene name: HAVCR1-TIMD4
Fusion gene ID: 35669
HgeneTgene
Gene symbol

HAVCR1

TIMD4

Gene ID

26762

91937

Gene namehepatitis A virus cellular receptor 1T cell immunoglobulin and mucin domain containing 4
SynonymsCD365|HAVCR|HAVCR-1|KIM-1|KIM1|TIM|TIM-1|TIM1|TIMD-1|TIMD1SMUCKLER|TIM4
Cytomap

5q33.3

5q33.3

Type of geneprotein-codingprotein-coding
Descriptionhepatitis A virus cellular receptor 1T cell immunoglobin domain and mucin domain protein 1T-cell immunoglobulin mucin family member 1T-cell immunoglobulin mucin receptor 1T-cell membrane protein 1kidney injury molecule 1T-cell immunoglobulin and mucin domain-containing protein 4T-cell immunoglobulin mucin receptor 4T-cell membrane protein 4TIM-4TIMD-4
Modification date2020032920200313
UniProtAcc

Q96D42

.
Ensembl transtripts involved in fusion geneENST00000339252, ENST00000425854, 
ENST00000522693, ENST00000523175, 
ENST00000544197, ENST00000517644, 
ENST00000406964, ENST00000274532, 
ENST00000407087, 
Fusion gene scores* DoF score3 X 3 X 3=271 X 1 X 1=1
# samples 31
** MAII scorelog2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(1/1*10)=3.32192809488736
Context

PubMed: HAVCR1 [Title/Abstract] AND TIMD4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointHAVCR1(156464258)-TIMD4(156353323), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across HAVCR1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TIMD4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4KIRCTCGA-A3-3322-01AHAVCR1chr5

156464258

-TIMD4chr5

156353323

-


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Fusion Gene ORF analysis for HAVCR1-TIMD4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000339252ENST00000406964HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
5CDS-5UTRENST00000425854ENST00000406964HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
5CDS-5UTRENST00000522693ENST00000406964HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
5CDS-5UTRENST00000523175ENST00000406964HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
5CDS-5UTRENST00000544197ENST00000406964HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
5UTR-3CDSENST00000517644ENST00000274532HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
5UTR-3CDSENST00000517644ENST00000407087HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
5UTR-5UTRENST00000517644ENST00000406964HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
Frame-shiftENST00000522693ENST00000274532HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
Frame-shiftENST00000522693ENST00000407087HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
Frame-shiftENST00000523175ENST00000274532HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
Frame-shiftENST00000523175ENST00000407087HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
In-frameENST00000339252ENST00000274532HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
In-frameENST00000339252ENST00000407087HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
In-frameENST00000425854ENST00000274532HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
In-frameENST00000425854ENST00000407087HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
In-frameENST00000544197ENST00000274532HAVCR1chr5

156464258

-TIMD4chr5

156353323

-
In-frameENST00000544197ENST00000407087HAVCR1chr5

156464258

-TIMD4chr5

156353323

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000339252HAVCR1chr5156464258-ENST00000274532TIMD4chr5156353323-195314855031777424
ENST00000339252HAVCR1chr5156464258-ENST00000407087TIMD4chr5156353323-184614855031777424
ENST00000544197HAVCR1chr5156464258-ENST00000274532TIMD4chr5156353323-160511371851429414
ENST00000544197HAVCR1chr5156464258-ENST00000407087TIMD4chr5156353323-149811371851429414
ENST00000425854HAVCR1chr5156464258-ENST00000274532TIMD4chr5156353323-195314855031777424
ENST00000425854HAVCR1chr5156464258-ENST00000407087TIMD4chr5156353323-184614855031777424

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000339252ENST00000274532HAVCR1chr5156464258-TIMD4chr5156353323-0.0014612830.99853873
ENST00000339252ENST00000407087HAVCR1chr5156464258-TIMD4chr5156353323-0.0017647050.9982352
ENST00000544197ENST00000274532HAVCR1chr5156464258-TIMD4chr5156353323-0.0013222110.9986778
ENST00000544197ENST00000407087HAVCR1chr5156464258-TIMD4chr5156353323-0.0016126280.99838734
ENST00000425854ENST00000274532HAVCR1chr5156464258-TIMD4chr5156353323-0.0014612830.99853873
ENST00000425854ENST00000407087HAVCR1chr5156464258-TIMD4chr5156353323-0.0017647050.9982352

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Fusion Genomic Features for HAVCR1-TIMD4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for HAVCR1-TIMD4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:156464258/chr5:156353323)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
HAVCR1

Q96D42

.
FUNCTION: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). May play a role in kidney injury and repair. {ECO:0000250, ECO:0000269|PubMed:17471468}.; FUNCTION: (Microbial infection) Acts as a receptor for Hepatitis A virus. {ECO:0000269|PubMed:29437974, ECO:0000269|PubMed:9658108}.; FUNCTION: (Microbial infection) Acts as a receptor for Ebolavirus and Marburg virus by binding exposed phosphatidyl-serine at the surface of virion membrane (PubMed:21536871). Serves as a dual receptor for Ebolavirus by also interacting with envelope glycoprotein GP (PubMed:26487564). {ECO:0000269|PubMed:21536871, ECO:0000269|PubMed:26487564}.; FUNCTION: (Microbial infection) Acts as a receptor for Dengue virus by binding exposed phosphatidyl-serine at the surface of virion membrane. {ECO:0000269|PubMed:23084921}.; FUNCTION: (Microbial infection) Acts as a receptor for Zika virus by binding to envelope protein E. {ECO:0000269|PubMed:32641828}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68130_210317365.0Compositional biasNote=Thr-rich
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79130_210317365.0Compositional biasNote=Thr-rich
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79130_210317365.0Compositional biasNote=Thr-rich
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-6821_121317365.0DomainNote=Ig-like V-type
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-7921_121317365.0DomainNote=Ig-like V-type
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-7921_121317365.0DomainNote=Ig-like V-type
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68138_207317365.0RegionNote=12 X 6 AA approximate tandem repeats of V-P-T-T-T-T]
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79138_207317365.0RegionNote=12 X 6 AA approximate tandem repeats of V-P-T-T-T-T]
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79138_207317365.0RegionNote=12 X 6 AA approximate tandem repeats of V-P-T-T-T-T]
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68138_143317365.0RepeatNote=1
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68144_149317365.0RepeatNote=2
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68150_155317365.0RepeatNote=3
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68156_160317365.0RepeatNote=4
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68161_165317365.0RepeatNote=5
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68166_171317365.0RepeatNote=6
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68172_177317365.0RepeatNote=7
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68178_183317365.0RepeatNote=8
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68184_189317365.0RepeatNote=9
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68190_195317365.0RepeatNote=10
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68196_201317365.0RepeatNote=11
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68202_207317365.0RepeatNote=12
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79138_143317365.0RepeatNote=1
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79144_149317365.0RepeatNote=2
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79150_155317365.0RepeatNote=3
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79156_160317365.0RepeatNote=4
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79161_165317365.0RepeatNote=5
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79166_171317365.0RepeatNote=6
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79172_177317365.0RepeatNote=7
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79178_183317365.0RepeatNote=8
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79184_189317365.0RepeatNote=9
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79190_195317365.0RepeatNote=10
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79196_201317365.0RepeatNote=11
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79202_207317365.0RepeatNote=12
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79138_143317365.0RepeatNote=1
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79144_149317365.0RepeatNote=2
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79150_155317365.0RepeatNote=3
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79156_160317365.0RepeatNote=4
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79161_165317365.0RepeatNote=5
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79166_171317365.0RepeatNote=6
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79172_177317365.0RepeatNote=7
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79178_183317365.0RepeatNote=8
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79184_189317365.0RepeatNote=9
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79190_195317365.0RepeatNote=10
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79196_201317365.0RepeatNote=11
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79202_207317365.0RepeatNote=12
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-6821_295317365.0Topological domainExtracellular
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-7921_295317365.0Topological domainExtracellular
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-7921_295317365.0Topological domainExtracellular
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68296_316317365.0TransmembraneHelical
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79296_316317365.0TransmembraneHelical
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79296_316317365.0TransmembraneHelical
TgeneTIMD4chr5:156464258chr5:156353323ENST0000027453249336_378281379.0Topological domainCytoplasmic
TgeneTIMD4chr5:156464258chr5:156353323ENST0000040708738336_378253351.0Topological domainCytoplasmic
TgeneTIMD4chr5:156464258chr5:156353323ENST0000027453249315_335281379.0TransmembraneHelical
TgeneTIMD4chr5:156464258chr5:156353323ENST0000040708738315_335253351.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000339252-68317_364317365.0Topological domainCytoplasmic
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000523175-79317_364317365.0Topological domainCytoplasmic
HgeneHAVCR1chr5:156464258chr5:156353323ENST00000544197-79317_364317365.0Topological domainCytoplasmic
TgeneTIMD4chr5:156464258chr5:156353323ENST0000027453249136_214281379.0Compositional biasNote=Thr-rich
TgeneTIMD4chr5:156464258chr5:156353323ENST0000027453249234_277281379.0Compositional biasNote=Ser-rich
TgeneTIMD4chr5:156464258chr5:156353323ENST0000040708738136_214253351.0Compositional biasNote=Thr-rich
TgeneTIMD4chr5:156464258chr5:156353323ENST0000040708738234_277253351.0Compositional biasNote=Ser-rich
TgeneTIMD4chr5:156464258chr5:156353323ENST000002745324925_126281379.0DomainNote=Ig-like V-type
TgeneTIMD4chr5:156464258chr5:156353323ENST000004070873825_126253351.0DomainNote=Ig-like V-type
TgeneTIMD4chr5:156464258chr5:156353323ENST000002745324925_314281379.0Topological domainExtracellular
TgeneTIMD4chr5:156464258chr5:156353323ENST000004070873825_314253351.0Topological domainExtracellular


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Fusion Gene Sequence for HAVCR1-TIMD4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>35669_35669_1_HAVCR1-TIMD4_HAVCR1_chr5_156464258_ENST00000339252_TIMD4_chr5_156353323_ENST00000274532_length(transcript)=1953nt_BP=1485nt
ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCAGTGACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGG
TTTCACCCTTTTAGCCAGGATGGTCTCGATCTCCTGACTTCGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTAGGATTACAGGTTTGAG
CCACCGCGCCCGGCCCTGTTTCCTTTTTGTTTGTTCCCCTGATACCCTGTATCAGGACCAGGAGTCAGTTTGGCGGTTATGTGTGGGGAA
GAAGCTGGGAAGTCAGGGGCTGTTTCTGTGGACAGCTTTCCCTGTCCTTTGGAAGGCACAGAGCTCTCAGCTGCAGGGAACTAACAGAGC
TCTGAAGCCGTTATATGTGGTCTTCTCTCATTTCCAGCAGAGCAGGCTCATATGAATCAACCAACTGGGTGAAAAGATAAGTTGCAATCT
GAGATTTAAGACTTGATCAGATACCATCTGGTGGAGGGTACCAACCAGCCTGTCTGCTCATTTTCCTTCAGGCTGATCCCATAATGCATC
CTCAAGTGGTCATCTTAAGCCTCATCCTACATCTGGCAGATTCTGTAGCTGGTTCTGTAAAGGTTGGTGGAGAGGCAGGTCCATCTGTCA
CACTACCCTGCCACTACAGTGGAGCTGTCACATCCATGTGCTGGAATAGAGGCTCATGTTCTCTATTCACATGCCAAAATGGCATTGTCT
GGACCAATGGAACCCACGTCACCTATCGGAAGGACACACGCTATAAGCTATTGGGGGACCTTTCAAGAAGGGATGTCTCTTTGACCATAG
AAAATACAGCTGTGTCTGACAGTGGCGTATATTGTTGCCGTGTTGAGCACCGTGGGTGGTTCAATGACATGAAAATCACCGTATCATTGG
AGATTGTGCCACCCAAGGTCACGACTACTCCAATTGTCACAACTGTTCCAACCGTCACGACTGTTCGAACGAGCACCACTGTTCCAACGA
CAACGACTGTTCCAATGACGACTGTTCCAACGACAACTGTTCCAACAACAATGAGCATTCCAACGACAACGACTGTTCTGACGACAATGA
CTGTTTCAACGACAACGAGCGTTCCAACGACAACGAGCATTCCAACAACAACAAGTGTTCCAGTGACAACAACTGTCTCTACCTTTGTTC
CTCCAATGCCTTTGCCCAGGCAGAACCATGAACCAGTAGCCACTTCACCATCTTCACCTCAGCCAGCAGAAACCCACCCTACGACACTGC
AGGGAGCAATAAGGAGAGAACCCACCAGCTCACCATTGTACTCTTACACAACAGATGGGAATGACACCGTGACAGAGTCTTCAGATGGCC
TTTGGAATAACAATCAAACTCAACTGTTCCTAGAACATAGTCTACTGACGGCCAATACCACTAAAGGAATCTATGCTGGAGTCTGTATTT
CTGTCTTGGTGCTTCTTGCTCTTTTGGGTGTCATCATTGCCAAAACATCTGATACAGCAGTTCCTGAGCAGAACAAAACAACAAAAACAG
GACAGATGGATGGAATACCCATGTCAATGAAGAATGAAATGCCCATCTCCCAACTACTGATGATCATCGCCCCCTCCTTGGGATTTGTGC
TCTTCGCATTGTTTGTGGCGTTTCTCCTGAGAGGGAAACTCATGGAAACCTATTGTTCGCAGAAACACACAAGGCTAGACTACATTGGAG
ATAGTAAAAATGTCCTCAATGACGTGCAGCATGGAAGGGAAGACGAAGACGGCCTTTTTACCCTCTAACAACGCAGTAGCATGTTAGATT
GAGGATGGGGGCATGACACTCCAGTGTCAAAATAAGTCTTAGTAGATTTCCTTGTTTCATAAAAAAGACTCACTTATTCCATGGATGTCA

>35669_35669_1_HAVCR1-TIMD4_HAVCR1_chr5_156464258_ENST00000339252_TIMD4_chr5_156353323_ENST00000274532_length(amino acids)=424AA_BP=1
MLIFLQADPIMHPQVVILSLILHLADSVAGSVKVGGEAGPSVTLPCHYSGAVTSMCWNRGSCSLFTCQNGIVWTNGTHVTYRKDTRYKLL
GDLSRRDVSLTIENTAVSDSGVYCCRVEHRGWFNDMKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTM
SIPTTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPSSPQPAETHPTTLQGAIRREPTSSPLYSYTT
DGNDTVTESSDGLWNNNQTQLFLEHSLLTANTTKGIYAGVCISVLVLLALLGVIIAKTSDTAVPEQNKTTKTGQMDGIPMSMKNEMPISQ

--------------------------------------------------------------
>35669_35669_2_HAVCR1-TIMD4_HAVCR1_chr5_156464258_ENST00000339252_TIMD4_chr5_156353323_ENST00000407087_length(transcript)=1846nt_BP=1485nt
ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCAGTGACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGG
TTTCACCCTTTTAGCCAGGATGGTCTCGATCTCCTGACTTCGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTAGGATTACAGGTTTGAG
CCACCGCGCCCGGCCCTGTTTCCTTTTTGTTTGTTCCCCTGATACCCTGTATCAGGACCAGGAGTCAGTTTGGCGGTTATGTGTGGGGAA
GAAGCTGGGAAGTCAGGGGCTGTTTCTGTGGACAGCTTTCCCTGTCCTTTGGAAGGCACAGAGCTCTCAGCTGCAGGGAACTAACAGAGC
TCTGAAGCCGTTATATGTGGTCTTCTCTCATTTCCAGCAGAGCAGGCTCATATGAATCAACCAACTGGGTGAAAAGATAAGTTGCAATCT
GAGATTTAAGACTTGATCAGATACCATCTGGTGGAGGGTACCAACCAGCCTGTCTGCTCATTTTCCTTCAGGCTGATCCCATAATGCATC
CTCAAGTGGTCATCTTAAGCCTCATCCTACATCTGGCAGATTCTGTAGCTGGTTCTGTAAAGGTTGGTGGAGAGGCAGGTCCATCTGTCA
CACTACCCTGCCACTACAGTGGAGCTGTCACATCCATGTGCTGGAATAGAGGCTCATGTTCTCTATTCACATGCCAAAATGGCATTGTCT
GGACCAATGGAACCCACGTCACCTATCGGAAGGACACACGCTATAAGCTATTGGGGGACCTTTCAAGAAGGGATGTCTCTTTGACCATAG
AAAATACAGCTGTGTCTGACAGTGGCGTATATTGTTGCCGTGTTGAGCACCGTGGGTGGTTCAATGACATGAAAATCACCGTATCATTGG
AGATTGTGCCACCCAAGGTCACGACTACTCCAATTGTCACAACTGTTCCAACCGTCACGACTGTTCGAACGAGCACCACTGTTCCAACGA
CAACGACTGTTCCAATGACGACTGTTCCAACGACAACTGTTCCAACAACAATGAGCATTCCAACGACAACGACTGTTCTGACGACAATGA
CTGTTTCAACGACAACGAGCGTTCCAACGACAACGAGCATTCCAACAACAACAAGTGTTCCAGTGACAACAACTGTCTCTACCTTTGTTC
CTCCAATGCCTTTGCCCAGGCAGAACCATGAACCAGTAGCCACTTCACCATCTTCACCTCAGCCAGCAGAAACCCACCCTACGACACTGC
AGGGAGCAATAAGGAGAGAACCCACCAGCTCACCATTGTACTCTTACACAACAGATGGGAATGACACCGTGACAGAGTCTTCAGATGGCC
TTTGGAATAACAATCAAACTCAACTGTTCCTAGAACATAGTCTACTGACGGCCAATACCACTAAAGGAATCTATGCTGGAGTCTGTATTT
CTGTCTTGGTGCTTCTTGCTCTTTTGGGTGTCATCATTGCCAAAACATCTGATACAGCAGTTCCTGAGCAGAACAAAACAACAAAAACAG
GACAGATGGATGGAATACCCATGTCAATGAAGAATGAAATGCCCATCTCCCAACTACTGATGATCATCGCCCCCTCCTTGGGATTTGTGC
TCTTCGCATTGTTTGTGGCGTTTCTCCTGAGAGGGAAACTCATGGAAACCTATTGTTCGCAGAAACACACAAGGCTAGACTACATTGGAG
ATAGTAAAAATGTCCTCAATGACGTGCAGCATGGAAGGGAAGACGAAGACGGCCTTTTTACCCTCTAACAACGCAGTAGCATGTTAGATT

>35669_35669_2_HAVCR1-TIMD4_HAVCR1_chr5_156464258_ENST00000339252_TIMD4_chr5_156353323_ENST00000407087_length(amino acids)=424AA_BP=1
MLIFLQADPIMHPQVVILSLILHLADSVAGSVKVGGEAGPSVTLPCHYSGAVTSMCWNRGSCSLFTCQNGIVWTNGTHVTYRKDTRYKLL
GDLSRRDVSLTIENTAVSDSGVYCCRVEHRGWFNDMKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTM
SIPTTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPSSPQPAETHPTTLQGAIRREPTSSPLYSYTT
DGNDTVTESSDGLWNNNQTQLFLEHSLLTANTTKGIYAGVCISVLVLLALLGVIIAKTSDTAVPEQNKTTKTGQMDGIPMSMKNEMPISQ

--------------------------------------------------------------
>35669_35669_3_HAVCR1-TIMD4_HAVCR1_chr5_156464258_ENST00000425854_TIMD4_chr5_156353323_ENST00000274532_length(transcript)=1953nt_BP=1485nt
ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCAGTGACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGG
TTTCACCCTTTTAGCCAGGATGGTCTCGATCTCCTGACTTCGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTAGGATTACAGGTTTGAG
CCACCGCGCCCGGCCCTGTTTCCTTTTTGTTTGTTCCCCTGATACCCTGTATCAGGACCAGGAGTCAGTTTGGCGGTTATGTGTGGGGAA
GAAGCTGGGAAGTCAGGGGCTGTTTCTGTGGACAGCTTTCCCTGTCCTTTGGAAGGCACAGAGCTCTCAGCTGCAGGGAACTAACAGAGC
TCTGAAGCCGTTATATGTGGTCTTCTCTCATTTCCAGCAGAGCAGGCTCATATGAATCAACCAACTGGGTGAAAAGATAAGTTGCAATCT
GAGATTTAAGACTTGATCAGATACCATCTGGTGGAGGGTACCAACCAGCCTGTCTGCTCATTTTCCTTCAGGCTGATCCCATAATGCATC
CTCAAGTGGTCATCTTAAGCCTCATCCTACATCTGGCAGATTCTGTAGCTGGTTCTGTAAAGGTTGGTGGAGAGGCAGGTCCATCTGTCA
CACTACCCTGCCACTACAGTGGAGCTGTCACATCCATGTGCTGGAATAGAGGCTCATGTTCTCTATTCACATGCCAAAATGGCATTGTCT
GGACCAATGGAACCCACGTCACCTATCGGAAGGACACACGCTATAAGCTATTGGGGGACCTTTCAAGAAGGGATGTCTCTTTGACCATAG
AAAATACAGCTGTGTCTGACAGTGGCGTATATTGTTGCCGTGTTGAGCACCGTGGGTGGTTCAATGACATGAAAATCACCGTATCATTGG
AGATTGTGCCACCCAAGGTCACGACTACTCCAATTGTCACAACTGTTCCAACCGTCACGACTGTTCGAACGAGCACCACTGTTCCAACGA
CAACGACTGTTCCAATGACGACTGTTCCAACGACAACTGTTCCAACAACAATGAGCATTCCAACGACAACGACTGTTCTGACGACAATGA
CTGTTTCAACGACAACGAGCGTTCCAACGACAACGAGCATTCCAACAACAACAAGTGTTCCAGTGACAACAACTGTCTCTACCTTTGTTC
CTCCAATGCCTTTGCCCAGGCAGAACCATGAACCAGTAGCCACTTCACCATCTTCACCTCAGCCAGCAGAAACCCACCCTACGACACTGC
AGGGAGCAATAAGGAGAGAACCCACCAGCTCACCATTGTACTCTTACACAACAGATGGGAATGACACCGTGACAGAGTCTTCAGATGGCC
TTTGGAATAACAATCAAACTCAACTGTTCCTAGAACATAGTCTACTGACGGCCAATACCACTAAAGGAATCTATGCTGGAGTCTGTATTT
CTGTCTTGGTGCTTCTTGCTCTTTTGGGTGTCATCATTGCCAAAACATCTGATACAGCAGTTCCTGAGCAGAACAAAACAACAAAAACAG
GACAGATGGATGGAATACCCATGTCAATGAAGAATGAAATGCCCATCTCCCAACTACTGATGATCATCGCCCCCTCCTTGGGATTTGTGC
TCTTCGCATTGTTTGTGGCGTTTCTCCTGAGAGGGAAACTCATGGAAACCTATTGTTCGCAGAAACACACAAGGCTAGACTACATTGGAG
ATAGTAAAAATGTCCTCAATGACGTGCAGCATGGAAGGGAAGACGAAGACGGCCTTTTTACCCTCTAACAACGCAGTAGCATGTTAGATT
GAGGATGGGGGCATGACACTCCAGTGTCAAAATAAGTCTTAGTAGATTTCCTTGTTTCATAAAAAAGACTCACTTATTCCATGGATGTCA

>35669_35669_3_HAVCR1-TIMD4_HAVCR1_chr5_156464258_ENST00000425854_TIMD4_chr5_156353323_ENST00000274532_length(amino acids)=424AA_BP=1
MLIFLQADPIMHPQVVILSLILHLADSVAGSVKVGGEAGPSVTLPCHYSGAVTSMCWNRGSCSLFTCQNGIVWTNGTHVTYRKDTRYKLL
GDLSRRDVSLTIENTAVSDSGVYCCRVEHRGWFNDMKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTM
SIPTTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPSSPQPAETHPTTLQGAIRREPTSSPLYSYTT
DGNDTVTESSDGLWNNNQTQLFLEHSLLTANTTKGIYAGVCISVLVLLALLGVIIAKTSDTAVPEQNKTTKTGQMDGIPMSMKNEMPISQ

--------------------------------------------------------------
>35669_35669_4_HAVCR1-TIMD4_HAVCR1_chr5_156464258_ENST00000425854_TIMD4_chr5_156353323_ENST00000407087_length(transcript)=1846nt_BP=1485nt
ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCAGTGACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGG
TTTCACCCTTTTAGCCAGGATGGTCTCGATCTCCTGACTTCGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTAGGATTACAGGTTTGAG
CCACCGCGCCCGGCCCTGTTTCCTTTTTGTTTGTTCCCCTGATACCCTGTATCAGGACCAGGAGTCAGTTTGGCGGTTATGTGTGGGGAA
GAAGCTGGGAAGTCAGGGGCTGTTTCTGTGGACAGCTTTCCCTGTCCTTTGGAAGGCACAGAGCTCTCAGCTGCAGGGAACTAACAGAGC
TCTGAAGCCGTTATATGTGGTCTTCTCTCATTTCCAGCAGAGCAGGCTCATATGAATCAACCAACTGGGTGAAAAGATAAGTTGCAATCT
GAGATTTAAGACTTGATCAGATACCATCTGGTGGAGGGTACCAACCAGCCTGTCTGCTCATTTTCCTTCAGGCTGATCCCATAATGCATC
CTCAAGTGGTCATCTTAAGCCTCATCCTACATCTGGCAGATTCTGTAGCTGGTTCTGTAAAGGTTGGTGGAGAGGCAGGTCCATCTGTCA
CACTACCCTGCCACTACAGTGGAGCTGTCACATCCATGTGCTGGAATAGAGGCTCATGTTCTCTATTCACATGCCAAAATGGCATTGTCT
GGACCAATGGAACCCACGTCACCTATCGGAAGGACACACGCTATAAGCTATTGGGGGACCTTTCAAGAAGGGATGTCTCTTTGACCATAG
AAAATACAGCTGTGTCTGACAGTGGCGTATATTGTTGCCGTGTTGAGCACCGTGGGTGGTTCAATGACATGAAAATCACCGTATCATTGG
AGATTGTGCCACCCAAGGTCACGACTACTCCAATTGTCACAACTGTTCCAACCGTCACGACTGTTCGAACGAGCACCACTGTTCCAACGA
CAACGACTGTTCCAATGACGACTGTTCCAACGACAACTGTTCCAACAACAATGAGCATTCCAACGACAACGACTGTTCTGACGACAATGA
CTGTTTCAACGACAACGAGCGTTCCAACGACAACGAGCATTCCAACAACAACAAGTGTTCCAGTGACAACAACTGTCTCTACCTTTGTTC
CTCCAATGCCTTTGCCCAGGCAGAACCATGAACCAGTAGCCACTTCACCATCTTCACCTCAGCCAGCAGAAACCCACCCTACGACACTGC
AGGGAGCAATAAGGAGAGAACCCACCAGCTCACCATTGTACTCTTACACAACAGATGGGAATGACACCGTGACAGAGTCTTCAGATGGCC
TTTGGAATAACAATCAAACTCAACTGTTCCTAGAACATAGTCTACTGACGGCCAATACCACTAAAGGAATCTATGCTGGAGTCTGTATTT
CTGTCTTGGTGCTTCTTGCTCTTTTGGGTGTCATCATTGCCAAAACATCTGATACAGCAGTTCCTGAGCAGAACAAAACAACAAAAACAG
GACAGATGGATGGAATACCCATGTCAATGAAGAATGAAATGCCCATCTCCCAACTACTGATGATCATCGCCCCCTCCTTGGGATTTGTGC
TCTTCGCATTGTTTGTGGCGTTTCTCCTGAGAGGGAAACTCATGGAAACCTATTGTTCGCAGAAACACACAAGGCTAGACTACATTGGAG
ATAGTAAAAATGTCCTCAATGACGTGCAGCATGGAAGGGAAGACGAAGACGGCCTTTTTACCCTCTAACAACGCAGTAGCATGTTAGATT

>35669_35669_4_HAVCR1-TIMD4_HAVCR1_chr5_156464258_ENST00000425854_TIMD4_chr5_156353323_ENST00000407087_length(amino acids)=424AA_BP=1
MLIFLQADPIMHPQVVILSLILHLADSVAGSVKVGGEAGPSVTLPCHYSGAVTSMCWNRGSCSLFTCQNGIVWTNGTHVTYRKDTRYKLL
GDLSRRDVSLTIENTAVSDSGVYCCRVEHRGWFNDMKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTM
SIPTTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPSSPQPAETHPTTLQGAIRREPTSSPLYSYTT
DGNDTVTESSDGLWNNNQTQLFLEHSLLTANTTKGIYAGVCISVLVLLALLGVIIAKTSDTAVPEQNKTTKTGQMDGIPMSMKNEMPISQ

--------------------------------------------------------------
>35669_35669_5_HAVCR1-TIMD4_HAVCR1_chr5_156464258_ENST00000544197_TIMD4_chr5_156353323_ENST00000274532_length(transcript)=1605nt_BP=1137nt
ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCAGTGACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGG
TTTCACCCTTTTAGCCAGGATGGTCTCGATCTCCTGACTTCGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTAGGATTACAGGCTGATC
CCATAATGCATCCTCAAGTGGTCATCTTAAGCCTCATCCTACATCTGGCAGATTCTGTAGCTGGTTCTGTAAAGGTTGGTGGAGAGGCAG
GTCCATCTGTCACACTACCCTGCCACTACAGTGGAGCTGTCACATCCATGTGCTGGAATAGAGGCTCATGTTCTCTATTCACATGCCAAA
ATGGCATTGTCTGGACCAATGGAACCCACGTCACCTATCGGAAGGACACACGCTATAAGCTATTGGGGGACCTTTCAAGAAGGGATGTCT
CTTTGACCATAGAAAATACAGCTGTGTCTGACAGTGGCGTATATTGTTGCCGTGTTGAGCACCGTGGGTGGTTCAATGACATGAAAATCA
CCGTATCATTGGAGATTGTGCCACCCAAGGTCACGACTACTCCAATTGTCACAACTGTTCCAACCGTCACGACTGTTCGAACGAGCACCA
CTGTTCCAACGACAACGACTGTTCCAATGACGACTGTTCCAACGACAACTGTTCCAACAACAATGAGCATTCCAACGACAACGACTGTTC
TGACGACAATGACTGTTTCAACGACAACGAGCGTTCCAACGACAACGAGCATTCCAACAACAACAAGTGTTCCAGTGACAACAACTGTCT
CTACCTTTGTTCCTCCAATGCCTTTGCCCAGGCAGAACCATGAACCAGTAGCCACTTCACCATCTTCACCTCAGCCAGCAGAAACCCACC
CTACGACACTGCAGGGAGCAATAAGGAGAGAACCCACCAGCTCACCATTGTACTCTTACACAACAGATGGGAATGACACCGTGACAGAGT
CTTCAGATGGCCTTTGGAATAACAATCAAACTCAACTGTTCCTAGAACATAGTCTACTGACGGCCAATACCACTAAAGGAATCTATGCTG
GAGTCTGTATTTCTGTCTTGGTGCTTCTTGCTCTTTTGGGTGTCATCATTGCCAAAACATCTGATACAGCAGTTCCTGAGCAGAACAAAA
CAACAAAAACAGGACAGATGGATGGAATACCCATGTCAATGAAGAATGAAATGCCCATCTCCCAACTACTGATGATCATCGCCCCCTCCT
TGGGATTTGTGCTCTTCGCATTGTTTGTGGCGTTTCTCCTGAGAGGGAAACTCATGGAAACCTATTGTTCGCAGAAACACACAAGGCTAG
ACTACATTGGAGATAGTAAAAATGTCCTCAATGACGTGCAGCATGGAAGGGAAGACGAAGACGGCCTTTTTACCCTCTAACAACGCAGTA
GCATGTTAGATTGAGGATGGGGGCATGACACTCCAGTGTCAAAATAAGTCTTAGTAGATTTCCTTGTTTCATAAAAAAGACTCACTTATT

>35669_35669_5_HAVCR1-TIMD4_HAVCR1_chr5_156464258_ENST00000544197_TIMD4_chr5_156353323_ENST00000274532_length(amino acids)=414AA_BP=0
MHPQVVILSLILHLADSVAGSVKVGGEAGPSVTLPCHYSGAVTSMCWNRGSCSLFTCQNGIVWTNGTHVTYRKDTRYKLLGDLSRRDVSL
TIENTAVSDSGVYCCRVEHRGWFNDMKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTMSIPTTTTVLT
TMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPSSPQPAETHPTTLQGAIRREPTSSPLYSYTTDGNDTVTESS
DGLWNNNQTQLFLEHSLLTANTTKGIYAGVCISVLVLLALLGVIIAKTSDTAVPEQNKTTKTGQMDGIPMSMKNEMPISQLLMIIAPSLG

--------------------------------------------------------------
>35669_35669_6_HAVCR1-TIMD4_HAVCR1_chr5_156464258_ENST00000544197_TIMD4_chr5_156353323_ENST00000407087_length(transcript)=1498nt_BP=1137nt
ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCAGTGACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGG
TTTCACCCTTTTAGCCAGGATGGTCTCGATCTCCTGACTTCGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTAGGATTACAGGCTGATC
CCATAATGCATCCTCAAGTGGTCATCTTAAGCCTCATCCTACATCTGGCAGATTCTGTAGCTGGTTCTGTAAAGGTTGGTGGAGAGGCAG
GTCCATCTGTCACACTACCCTGCCACTACAGTGGAGCTGTCACATCCATGTGCTGGAATAGAGGCTCATGTTCTCTATTCACATGCCAAA
ATGGCATTGTCTGGACCAATGGAACCCACGTCACCTATCGGAAGGACACACGCTATAAGCTATTGGGGGACCTTTCAAGAAGGGATGTCT
CTTTGACCATAGAAAATACAGCTGTGTCTGACAGTGGCGTATATTGTTGCCGTGTTGAGCACCGTGGGTGGTTCAATGACATGAAAATCA
CCGTATCATTGGAGATTGTGCCACCCAAGGTCACGACTACTCCAATTGTCACAACTGTTCCAACCGTCACGACTGTTCGAACGAGCACCA
CTGTTCCAACGACAACGACTGTTCCAATGACGACTGTTCCAACGACAACTGTTCCAACAACAATGAGCATTCCAACGACAACGACTGTTC
TGACGACAATGACTGTTTCAACGACAACGAGCGTTCCAACGACAACGAGCATTCCAACAACAACAAGTGTTCCAGTGACAACAACTGTCT
CTACCTTTGTTCCTCCAATGCCTTTGCCCAGGCAGAACCATGAACCAGTAGCCACTTCACCATCTTCACCTCAGCCAGCAGAAACCCACC
CTACGACACTGCAGGGAGCAATAAGGAGAGAACCCACCAGCTCACCATTGTACTCTTACACAACAGATGGGAATGACACCGTGACAGAGT
CTTCAGATGGCCTTTGGAATAACAATCAAACTCAACTGTTCCTAGAACATAGTCTACTGACGGCCAATACCACTAAAGGAATCTATGCTG
GAGTCTGTATTTCTGTCTTGGTGCTTCTTGCTCTTTTGGGTGTCATCATTGCCAAAACATCTGATACAGCAGTTCCTGAGCAGAACAAAA
CAACAAAAACAGGACAGATGGATGGAATACCCATGTCAATGAAGAATGAAATGCCCATCTCCCAACTACTGATGATCATCGCCCCCTCCT
TGGGATTTGTGCTCTTCGCATTGTTTGTGGCGTTTCTCCTGAGAGGGAAACTCATGGAAACCTATTGTTCGCAGAAACACACAAGGCTAG
ACTACATTGGAGATAGTAAAAATGTCCTCAATGACGTGCAGCATGGAAGGGAAGACGAAGACGGCCTTTTTACCCTCTAACAACGCAGTA

>35669_35669_6_HAVCR1-TIMD4_HAVCR1_chr5_156464258_ENST00000544197_TIMD4_chr5_156353323_ENST00000407087_length(amino acids)=414AA_BP=0
MHPQVVILSLILHLADSVAGSVKVGGEAGPSVTLPCHYSGAVTSMCWNRGSCSLFTCQNGIVWTNGTHVTYRKDTRYKLLGDLSRRDVSL
TIENTAVSDSGVYCCRVEHRGWFNDMKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTMSIPTTTTVLT
TMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPSSPQPAETHPTTLQGAIRREPTSSPLYSYTTDGNDTVTESS
DGLWNNNQTQLFLEHSLLTANTTKGIYAGVCISVLVLLALLGVIIAKTSDTAVPEQNKTTKTGQMDGIPMSMKNEMPISQLLMIIAPSLG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for HAVCR1-TIMD4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for HAVCR1-TIMD4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for HAVCR1-TIMD4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource