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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:HEATR1-TRMT2B (FusionGDB2 ID:35948)

Fusion Gene Summary for HEATR1-TRMT2B

Fusion gene summary

Fusion gene information	Fusion gene name: HEATR1-TRMT2B
	Fusion gene ID: 35948
		Hgene	Tgene
	Gene symbol	HEATR1	TRMT2B
	Gene ID	55127	79979
	Gene name	HEAT repeat containing 1	tRNA methyltransferase 2 homolog B
	Synonyms	BAP28\|UTP10	CXorf34\|dJ341D10.3
	Cytomap	1q43	Xq22.1
	Type of gene	protein-coding	protein-coding
	Description	HEAT repeat-containing protein 1U3 small nucleolar RNA-associated protein 10 homologUTP10, small subunit (SSU) processome component, homologprotein BAP28	tRNA (uracil(54)-C(5))-methyltransferase homologTRM2 homologTRM2 tRNA methyltransferase 2 homolog BtRNA (uracil-5-)-methyltransferase homolog
	Modification date	20200313	20200313
	UniProtAcc	Q9H583	.
	Ensembl transtripts involved in fusion gene	ENST00000366581, ENST00000366582, ENST00000366579, ENST00000483073,	ENST00000478422, ENST00000338687, ENST00000372931, ENST00000372935, ENST00000372936, ENST00000372939, ENST00000545398,
Fusion gene scores	* DoF score	6 X 7 X 5=210	2 X 2 X 2=8
	# samples	7	2
	** MAII score	log2(7/210*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(2/8*10)=1.32192809488736
Context	PubMed: HEATR1 [Title/Abstract] AND TRMT2B [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	HEATR1(236739519)-TRMT2B(100292062), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across HEATR1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TRMT2B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-BR-A4QI-01A	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-

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Fusion Gene ORF analysis for HEATR1-TRMT2B

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000366581	ENST00000478422	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
5CDS-5UTR	ENST00000366582	ENST00000478422	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
In-frame	ENST00000366581	ENST00000338687	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
In-frame	ENST00000366581	ENST00000372931	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
In-frame	ENST00000366581	ENST00000372935	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
In-frame	ENST00000366581	ENST00000372936	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
In-frame	ENST00000366581	ENST00000372939	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
In-frame	ENST00000366581	ENST00000545398	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
In-frame	ENST00000366582	ENST00000338687	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
In-frame	ENST00000366582	ENST00000372931	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
In-frame	ENST00000366582	ENST00000372935	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
In-frame	ENST00000366582	ENST00000372936	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
In-frame	ENST00000366582	ENST00000372939	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
In-frame	ENST00000366582	ENST00000545398	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-3CDS	ENST00000366579	ENST00000338687	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-3CDS	ENST00000366579	ENST00000372931	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-3CDS	ENST00000366579	ENST00000372935	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-3CDS	ENST00000366579	ENST00000372936	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-3CDS	ENST00000366579	ENST00000372939	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-3CDS	ENST00000366579	ENST00000545398	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-3CDS	ENST00000483073	ENST00000338687	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-3CDS	ENST00000483073	ENST00000372931	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-3CDS	ENST00000483073	ENST00000372935	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-3CDS	ENST00000483073	ENST00000372936	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-3CDS	ENST00000483073	ENST00000372939	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-3CDS	ENST00000483073	ENST00000545398	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-5UTR	ENST00000366579	ENST00000478422	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-
intron-5UTR	ENST00000483073	ENST00000478422	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000366582	HEATR1	chr1	236739519	-	ENST00000338687	TRMT2B	chrX	100292062	-	5511	3199	115	4275	1386
ENST00000366582	HEATR1	chr1	236739519	-	ENST00000545398	TRMT2B	chrX	100292062	-	5511	3199	115	4275	1386
ENST00000366582	HEATR1	chr1	236739519	-	ENST00000372939	TRMT2B	chrX	100292062	-	5507	3199	115	4275	1386
ENST00000366582	HEATR1	chr1	236739519	-	ENST00000372935	TRMT2B	chrX	100292062	-	5315	3199	115	4275	1386
ENST00000366582	HEATR1	chr1	236739519	-	ENST00000372936	TRMT2B	chrX	100292062	-	5315	3199	115	4275	1386
ENST00000366582	HEATR1	chr1	236739519	-	ENST00000372931	TRMT2B	chrX	100292062	-	4246	3199	115	4245	1377
ENST00000366581	HEATR1	chr1	236739519	-	ENST00000338687	TRMT2B	chrX	100292062	-	5511	3199	115	4275	1386
ENST00000366581	HEATR1	chr1	236739519	-	ENST00000545398	TRMT2B	chrX	100292062	-	5511	3199	115	4275	1386
ENST00000366581	HEATR1	chr1	236739519	-	ENST00000372939	TRMT2B	chrX	100292062	-	5507	3199	115	4275	1386
ENST00000366581	HEATR1	chr1	236739519	-	ENST00000372935	TRMT2B	chrX	100292062	-	5315	3199	115	4275	1386
ENST00000366581	HEATR1	chr1	236739519	-	ENST00000372936	TRMT2B	chrX	100292062	-	5315	3199	115	4275	1386
ENST00000366581	HEATR1	chr1	236739519	-	ENST00000372931	TRMT2B	chrX	100292062	-	4246	3199	115	4245	1377

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000366582	ENST00000338687	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-	0.000152126	0.9998479
ENST00000366582	ENST00000545398	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-	0.000152126	0.9998479
ENST00000366582	ENST00000372939	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-	0.000153044	0.99984694
ENST00000366582	ENST00000372935	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-	0.000172636	0.9998274
ENST00000366582	ENST00000372936	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-	0.000172636	0.9998274
ENST00000366582	ENST00000372931	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-	0.000400856	0.99959916
ENST00000366581	ENST00000338687	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-	0.000152126	0.9998479
ENST00000366581	ENST00000545398	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-	0.000152126	0.9998479
ENST00000366581	ENST00000372939	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-	0.000153044	0.99984694
ENST00000366581	ENST00000372935	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-	0.000172636	0.9998274
ENST00000366581	ENST00000372936	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-	0.000172636	0.9998274
ENST00000366581	ENST00000372931	HEATR1	chr1	236739519	-	TRMT2B	chrX	100292062	-	0.000400856	0.99959916

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Fusion Genomic Features for HEATR1-TRMT2B

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for HEATR1-TRMT2B

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:236739519/chrX:100292062)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
HEATR1 Q9H583	.
FUNCTION: Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. {ECO:0000269\|PubMed:17699751}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

HEATR1

chr1:236739519

chrX:100292062

ENST00000366582

2106_2142

1028

2145.0

Repeat

Note=HEAT

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Fusion Gene Sequence for HEATR1-TRMT2B

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>35948_35948_1_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366581_TRMT2B_chrX_100292062_ENST00000338687_length(transcript)=5511nt_BP=3199nt
GAGGGTTGGGCTCCTTGGTACCATGTGGGAAGCGCTGTGAAGAGTTGTTGCCTTCCAAGATATACCCAAATTCCCAGTTCCAGCCCGTGT
CATTAAAACTCCGCTGGCGTGAAAGATGACGTCCTTAGCCCAGCAGCTGCAACGACTCGCCCTCCCTCAAAGTGATGCCAGCCTCTTATC
TAGAGATGAAGTTGCTTCTTTGTTATTTGACCCTAAGGAAGCGGCCACAATCGACAGGGACACCGCCTTCGCCATTGGATGTACTGGCCT
GGAAGAGTTGCTTGGAATTGATCCTTCCTTTGAGCAGTTTGAAGCACCGTTGTTCAGTCAGCTAGCAAAAACCTTGGAGCGAAGTGTTCA
GACCAAAGCAGTAAACAAACAGTTGGATGAAAACATTTCATTATTCCTTATTCACTTGTCGCCTTACTTCCTGCTTAAGCCAGCACAGAA
GTGTCTGGAGTGGTTGATTCACAGGTTCCATATACATCTCTATAATCAAGATAGCCTCATTGCTTGTGTTCTGCCATACCACGAGACAAG
AATATTTGTGCGAGTCATACAGCTTCTAAAAATTAATAATTCAAAGCACAGATGGTTCTGGTTGTTGCCAGTTAAGCAATCTGGAGTGCC
GTTAGCTAAAGGAACTTTGATTACCCACTGCTACAAAGATCTTGGATTCATGGATTTCATTTGCAGTTTGGTGACAAAATCTGTGAAGGT
TTTTGCTGAGTACCCGGGCAGCTCAGCTCAGTTGAGGGTGCTCTTGGCTTTCTATGCTTCTACCATAGTGTCGGCGCTGGTAGCTGCAGA
GGACGTATCAGACAATATCATCGCCAAACTATTTCCCTATATCCAAAAGGGATTGAAATCATCTTTACCAGATTACAGAGCTGCAACATA
CATGATAATATGTCAGATTTCTGTGAAAGTGACCATGGAAAATACCTTTGTGAATTCATTGGCATCACAGATCATCAAAACATTGACCAA
GATTCCCTCTTTGATCAAGGATGGGTTAAGTTGCTTGATAGTGCTCCTGCAGAGACAGAAGCCAGAGAGCCTTGGGAAAAAGCCATTCCC
TCACTTATGTAATGTTCCTGATCTTATTACAATACTTCATGGGATTTCTGAAACTTACGATGTCAGTCCTCTTCTGCATTACATGCTTCC
CCATCTGGTCGTCTCCATCATTCATCATGTTACAGGAGAAGAAACTGAAGGAATGGATGGTCAAATCTACAAGAGACACTTAGAAGCTAT
ACTTACAAAAATATCACTGAAGAACAACTTAGACCATTTGTTGGCTAGCCTTCTATTTGAAGAGTATATTTCATATAGTTCACAGGAAGA
AATGGATTCTAATAAAGTGTCTTTGCTTAATGAACAATTTCTTCCACTCATTAGGCTTTTAGAAAGCAAATACCCCAGAACATTAGATGT
TGTATTAGAGGAACACTTAAAGGAAATTGCAGATCTGAAAAAACAAGAGCTTTTCCATCAGTTTGTTTCTCTTTCTACAAGTGGAGGAAA
GTATCAGTTTTTAGCAGATTCTGATACTTCTTTGATGCTCAGCCTGAATCATCCACTTGCTCCTGTGAGAATTCTGGCCATGAATCATTT
GAAAAAGATCATGAAAACATCAAAGGAGGGTGTTGATGAATCTTTCATAAAAGAAGCTGTTTTAGCCCGATTAGGTGATGATAATATAGA
TGTTGTTTTGTCGGCTATAAGTGCTTTTGAGATTTTCAAAGAACACTTCAGTTCAGAAGTGACGATTTCAAATCTTCTGAATCTCTTTCA
AAGAGCAGAACTTTCAAAGAATGGAGAATGGTACGAGGTACTTAAGATAGCCGCTGACATATTAATTAAAGAAGAGATACTGAGTGAAAA
TGATCAGTTGTCAAATCAGGTGGTTGTATGTTTGCTGCCATTTATGGTTATCAATAATGATGATACGGAATCTGCTGAGATGAAAATTGC
TATATATTTATCAAAATCAGGAATCTGCTCCCTGCACCCTCTATTAAGAGGCTGGGAAGAAGCTCTTGAAAATGTAATTAAAAGCACAAA
GCCAGGAAAACTAATCGGTGTAGCAAATCAGAAGATGATTGAGTTGTTGGCTGATAATATAAATTTAGGAGATCCTTCTTCAATGTTAAA
GATGGTGGAGGATTTAATAAGCGTGGGTGAGGAGGAGTCCTTTAACCTGAAGCAGAAAGTAACGTTTCATGTGATCCTGTCTGTGCTCGT
CTCTTGTTGTTCATCTTTAAAAGAAACCCACTTTCCATTTGCGATAAGAGTCTTCAGTTTGTTGCAGAAAAAAATAAAGAAGCTTGAAAG
TGTCATTACTGCAGTGGAAATCCCCTCAGAATGGCACATTGAACTGATGTTAGACAGAGGGATCCCAGTGGAGCTGTGGGCACATTATGT
AGAAGAGCTCAACAGCACTCAGAGGGTGGCCGTGGAGGACTCGGTTTTTCTTGTATTTTCCTTGAAAAAATTTATTTATGCACTGAAAGC
TCCTAAATCTTTTCCTAAAGGTGATATATGGTGGAATCCTGAACAACTGAAAGAAGACAGCAGGGACTATCTGCACTTGCTCATTGGGCT
GTTTGAGATGATGCTCAATGGTGCCGATGCTGTTCATTTCAGAGTTCTGATGAAACTTTTCATAAAGGTGCATCTAGAAGATGTTTTTCA
GTTATTCAAGTTCTGTTCTGTTTTATGGACCTATGGTTCTAGCCTTTCAAATCCACTAAACTGCAGTGTGAAAACAGTGCTGCAGACTCA
AGCTCTTTATGTGGGCTGTGCAATGCTTTCTTCTCAGAAGACACAGTGTAAACACCAACTGGCATCCATATCTTCTCCAGTGGTGACATC
TTTACTCATTAACCTGGGAAGCCCCGTAAAAGAAGTTCGTAGGGCTGCCATTCAGTGTCTCCAGGCCCTCAGTGGAGTGGCATCCCCGTT
TTATCTGATAATAGATCATTTGATTTCTAAAGCAGAGGAGATCACTTCAGATGCTGCCTATGTTATTCAGGATTTGGCTACTTTATTTGA
GGAACTACAGAGAGAAAAGAAACTGAAATCTCATCAGAAGTTGTCTGAAACTTTGAAAAACTTACTTAGTTGTGTGTATAGTTGCCCATC
TTATATAGCAAAAGATTTGATGAAAGTACTTCAGGGAGTCAACGGTGAGCCTGTCATCAATGGTTACCGAAATAAGTCCACCTTCTCTGT
GAACCGAGGTCCAGATGGCAATCCAAAGACTGTGGGGTTCTACCTGGGAACTTGGAGAGATGGGAACGTTGTCTGTGTGCAGTCTAATCA
TCTGAAAAACATCCCTGAGAAACACAGTCAAGTGGCGCAGTACTATGAAGTATTCCTTCGACAGTCTCCATTGGAGCCCTGCCTTGTATT
TCATGAAGGTGGATACTGGCGTGAGCTCACAGTCCGCACCAATAGCCAAGGGCACACAATGGCTATCATCACTTTCCATCCCCAGAAATT
AAGTCAGGAGGAGCTCCATGTTCAGAAGGAGATTGTAAAGGAATTTTTCATCAGAGGTCCTGGAGCAGCCTGTGGCTTGACCTCACTTTA
CTTCCAGGAAAGTACCATGACCCGTTGCAGCCATCAGCAGTCTCCCTATCAGCTTCTGTTTGGGGAACCCTACATCTTTGAAGAACTTCT
GAGCTTGAAGATCCGCATCTCTCCAGATGCCTTTTTCCAGATTAACACAGCTGGTGCAGAGATGCTGTATCGGACTGTGGGGGAGCTGAC
TGGAGTGAACTCTGACACCATCCTTCTTGACATCTGCTGTGGAACTGGTGTGATTGGCCTCTCTCTGGCTCAGCATACATCTCGGGTCCT
TGGGATTGAATTGTTGGAGCAGGCAGTGGAGGATGCAAGATGGACTGCAGCCTTCAATGGCATCACCAACTCTGAATTTCATACTGGTCA
AGCAGAGAAGATTTTGCCAGGGCTGCTAAAGTCAAAGGAAGATGGACAGTCAATTGTTGCTGTGGTGAACCCAGCCCGTGCCGGACTGCA
TTACAAGGTGATTCAAGCCATTCGAAACTTCAGGGCCATCCACACGCTAGTTTTTGTTTCCTGCAAGCTCCATGGTGAATCCACTAGGAA
TGTCATTGAGCTGTGCTGTCCTCCAGACCCTGCTAAGAAGCTCTTAGGCGAGCCCTTTGTCCTGCAGCAAGCTGTACCTGTGGATTTGTT
CCCTCACACCCCACATTGTGAGCTGGTGCTCCTCTTTACTCGATAAGCAGCCTCCTAGAAGACAGCAGGCTATTTGTTAAGGCTGAAGTT
TCAGAAACTTTCAGGTTTGGCATATTGCTACATTGCAGACCCTGGGAGCATTACAGTGGAAACCAATCTTTGGTTTGTGAATAGGAAGAA
TCTATTAGGCCTCTGGTCTGAGGCAGATTTTTTTTTTGAGATAGAGTCTCACTCTTGCCCAGGCTGGAGTGTCGTGGCGTGATCTCAGCT
CACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCTTCCCCAGTAGCTAGGATTAAAGGTGCGTGCCACCATGCCCGG
CTAATTTTTGTATTTTTGGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCGCCTCG
GCCTCTCAAAGTGCTGGGATTATAGGCGTGAGCCACCACACCCCGCCGCGGCTGACTTAACCTTAGATTTCAGATTCCCTTTCAATCATG
CCCGTTTGCTTGGGTTTGACCACTCCCCACTCCTGGATCTGGACTGTTTCTTCCTGTTGCTGTCAGCCTTGGTTCTAGTTTATAGTCTTG
TCTCCTCCGTTTCTGCTTATGGTGTGGACAAATGACCTTTTTTAAGCAGCTGGTAATAATTTTACATTGACTGGAGCCTGTGCATTTGCT
CAGAGATGCTACAATTTTTAGATATTTCTAAGACTTCTGGATTCTTGAGGTAGTTAAGGATTAAAACCAGAAACAGTCGAGGTTTTTTAA
AAGCAGGGTAAGCCATGAAGTGAATACAGGGTGACTGAGTGATCATCAGATGAGATTAATTCTTTTGGGTTTTCTTGGTTTTAAGGCATC
TCGAATGCCCCTTGAAAATGTAGTTTTCCCTGGTGGTGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATAATTGCTTGAA
CCTGGGAGGTGGAGGTTGCAGTGAGCTGAAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACACCATCTCAAAAAAAAAAAA
AAAAAGAAAATGTAGTTATCCCTAGGAGCAATAGCACCAATTAACTCTCACCCGTGGAGGAAGAATTGGTTATTGGAGAGACCCTAAGGG
AAAGGAGATTTTCAGAGAGACTGAATACCTATAATTGTGCTGTGTAGTGTGGAGGCAAAAAGCTCCAAAATCTAGTATAACATAATAAAC

>35948_35948_1_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366581_TRMT2B_chrX_100292062_ENST00000338687_length(amino acids)=1386AA_BP=1028
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQL
DENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT
HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISV
KVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH
HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKE
IADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA
FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGI
CSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE
THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGD
IWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM
LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKL
KSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKH
SQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTR
CSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQA
VEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPP

--------------------------------------------------------------
>35948_35948_2_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366581_TRMT2B_chrX_100292062_ENST00000372931_length(transcript)=4246nt_BP=3199nt
GAGGGTTGGGCTCCTTGGTACCATGTGGGAAGCGCTGTGAAGAGTTGTTGCCTTCCAAGATATACCCAAATTCCCAGTTCCAGCCCGTGT
CATTAAAACTCCGCTGGCGTGAAAGATGACGTCCTTAGCCCAGCAGCTGCAACGACTCGCCCTCCCTCAAAGTGATGCCAGCCTCTTATC
TAGAGATGAAGTTGCTTCTTTGTTATTTGACCCTAAGGAAGCGGCCACAATCGACAGGGACACCGCCTTCGCCATTGGATGTACTGGCCT
GGAAGAGTTGCTTGGAATTGATCCTTCCTTTGAGCAGTTTGAAGCACCGTTGTTCAGTCAGCTAGCAAAAACCTTGGAGCGAAGTGTTCA
GACCAAAGCAGTAAACAAACAGTTGGATGAAAACATTTCATTATTCCTTATTCACTTGTCGCCTTACTTCCTGCTTAAGCCAGCACAGAA
GTGTCTGGAGTGGTTGATTCACAGGTTCCATATACATCTCTATAATCAAGATAGCCTCATTGCTTGTGTTCTGCCATACCACGAGACAAG
AATATTTGTGCGAGTCATACAGCTTCTAAAAATTAATAATTCAAAGCACAGATGGTTCTGGTTGTTGCCAGTTAAGCAATCTGGAGTGCC
GTTAGCTAAAGGAACTTTGATTACCCACTGCTACAAAGATCTTGGATTCATGGATTTCATTTGCAGTTTGGTGACAAAATCTGTGAAGGT
TTTTGCTGAGTACCCGGGCAGCTCAGCTCAGTTGAGGGTGCTCTTGGCTTTCTATGCTTCTACCATAGTGTCGGCGCTGGTAGCTGCAGA
GGACGTATCAGACAATATCATCGCCAAACTATTTCCCTATATCCAAAAGGGATTGAAATCATCTTTACCAGATTACAGAGCTGCAACATA
CATGATAATATGTCAGATTTCTGTGAAAGTGACCATGGAAAATACCTTTGTGAATTCATTGGCATCACAGATCATCAAAACATTGACCAA
GATTCCCTCTTTGATCAAGGATGGGTTAAGTTGCTTGATAGTGCTCCTGCAGAGACAGAAGCCAGAGAGCCTTGGGAAAAAGCCATTCCC
TCACTTATGTAATGTTCCTGATCTTATTACAATACTTCATGGGATTTCTGAAACTTACGATGTCAGTCCTCTTCTGCATTACATGCTTCC
CCATCTGGTCGTCTCCATCATTCATCATGTTACAGGAGAAGAAACTGAAGGAATGGATGGTCAAATCTACAAGAGACACTTAGAAGCTAT
ACTTACAAAAATATCACTGAAGAACAACTTAGACCATTTGTTGGCTAGCCTTCTATTTGAAGAGTATATTTCATATAGTTCACAGGAAGA
AATGGATTCTAATAAAGTGTCTTTGCTTAATGAACAATTTCTTCCACTCATTAGGCTTTTAGAAAGCAAATACCCCAGAACATTAGATGT
TGTATTAGAGGAACACTTAAAGGAAATTGCAGATCTGAAAAAACAAGAGCTTTTCCATCAGTTTGTTTCTCTTTCTACAAGTGGAGGAAA
GTATCAGTTTTTAGCAGATTCTGATACTTCTTTGATGCTCAGCCTGAATCATCCACTTGCTCCTGTGAGAATTCTGGCCATGAATCATTT
GAAAAAGATCATGAAAACATCAAAGGAGGGTGTTGATGAATCTTTCATAAAAGAAGCTGTTTTAGCCCGATTAGGTGATGATAATATAGA
TGTTGTTTTGTCGGCTATAAGTGCTTTTGAGATTTTCAAAGAACACTTCAGTTCAGAAGTGACGATTTCAAATCTTCTGAATCTCTTTCA
AAGAGCAGAACTTTCAAAGAATGGAGAATGGTACGAGGTACTTAAGATAGCCGCTGACATATTAATTAAAGAAGAGATACTGAGTGAAAA
TGATCAGTTGTCAAATCAGGTGGTTGTATGTTTGCTGCCATTTATGGTTATCAATAATGATGATACGGAATCTGCTGAGATGAAAATTGC
TATATATTTATCAAAATCAGGAATCTGCTCCCTGCACCCTCTATTAAGAGGCTGGGAAGAAGCTCTTGAAAATGTAATTAAAAGCACAAA
GCCAGGAAAACTAATCGGTGTAGCAAATCAGAAGATGATTGAGTTGTTGGCTGATAATATAAATTTAGGAGATCCTTCTTCAATGTTAAA
GATGGTGGAGGATTTAATAAGCGTGGGTGAGGAGGAGTCCTTTAACCTGAAGCAGAAAGTAACGTTTCATGTGATCCTGTCTGTGCTCGT
CTCTTGTTGTTCATCTTTAAAAGAAACCCACTTTCCATTTGCGATAAGAGTCTTCAGTTTGTTGCAGAAAAAAATAAAGAAGCTTGAAAG
TGTCATTACTGCAGTGGAAATCCCCTCAGAATGGCACATTGAACTGATGTTAGACAGAGGGATCCCAGTGGAGCTGTGGGCACATTATGT
AGAAGAGCTCAACAGCACTCAGAGGGTGGCCGTGGAGGACTCGGTTTTTCTTGTATTTTCCTTGAAAAAATTTATTTATGCACTGAAAGC
TCCTAAATCTTTTCCTAAAGGTGATATATGGTGGAATCCTGAACAACTGAAAGAAGACAGCAGGGACTATCTGCACTTGCTCATTGGGCT
GTTTGAGATGATGCTCAATGGTGCCGATGCTGTTCATTTCAGAGTTCTGATGAAACTTTTCATAAAGGTGCATCTAGAAGATGTTTTTCA
GTTATTCAAGTTCTGTTCTGTTTTATGGACCTATGGTTCTAGCCTTTCAAATCCACTAAACTGCAGTGTGAAAACAGTGCTGCAGACTCA
AGCTCTTTATGTGGGCTGTGCAATGCTTTCTTCTCAGAAGACACAGTGTAAACACCAACTGGCATCCATATCTTCTCCAGTGGTGACATC
TTTACTCATTAACCTGGGAAGCCCCGTAAAAGAAGTTCGTAGGGCTGCCATTCAGTGTCTCCAGGCCCTCAGTGGAGTGGCATCCCCGTT
TTATCTGATAATAGATCATTTGATTTCTAAAGCAGAGGAGATCACTTCAGATGCTGCCTATGTTATTCAGGATTTGGCTACTTTATTTGA
GGAACTACAGAGAGAAAAGAAACTGAAATCTCATCAGAAGTTGTCTGAAACTTTGAAAAACTTACTTAGTTGTGTGTATAGTTGCCCATC
TTATATAGCAAAAGATTTGATGAAAGTACTTCAGGGAGTCAACGGTGAGCCTGTCATCAATGGTTACCGAAATAAGTCCACCTTCTCTGT
GAACCGAGGTCCAGATGGCAATCCAAAGACTGTGGGGTTCTACCTGGGAACTTGGAGAGATGGGAACGTTGTCTGTGTGCAGTCTAATCA
TCTGAAAAACATCCCTGAGAAACACAGTCAAGTGGCGCAGTACTATGAAGTATTCCTTCGACAGTCTCCATTGGAGCCCTGCCTTGTATT
TCATGAAGGTGGATACTGGCGTGAGCTCACAGTCCGCACCAATAGCCAAGGGCACACAATGGCTATCATCACTTTCCATCCCCAGAAATT
AAGTCAGGAGGAGCTCCATGTTCAGAAGGAGATTGTAAAGGAATTTTTCATCAGAGGTCCTGGAGCAGCCTGTGGCTTGACCTCACTTTA
CTTCCAGGAAAGTACCATGACCCGTTGCAGCCATCAGCAGTCTCCCTATCAGCTTCTGTTTGGGGAACCCTACATCTTTGAAGAACTTCT
GAGCTTGAAGATCCGCATCTCTCCAGATGCCTTTTTCCAGATTAACACAGCTGGTGCAGAGATGCTGTATCGGACTGTGGGGGAGCTGAC
TGGAGTGAACTCTGACACCATCCTTCTTGACATCTGCTGTGGAACTGGTGTGATTGGCCTCTCTCTGGCTCAGCATACATCTCGGGTCCT
TGGGATTGAATTGTTGGAGCAGGCAGTGGAGGATGCAAGATGGACTGCAGCCTTCAATGGCATCACCAACTCTGAATTTCATACTGGTCA
AGCAGAGAAGATTTTGCCAGGGCTGCTAAAGTCAAAGGAAGATGGACAGTCAATTGTTGCTGTGGTGAACCCAGCCCGTGCCGGACTGCA
TTACAAGGTGATTCAAGCCATTCGAAACTTCAGGGCCATCCACACGCTAGTTTTTGTTTCCTGCAAGCTCCATGGTGAATCCACTAGGAA
TGTCATTGAACGGAGTCTCATCTTGCTGGAGTGCAGTGGCATGGTCTCGGCTCACTACAGCCTCCACCTCCCAGGTTCAAGCGATTCTCC

>35948_35948_2_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366581_TRMT2B_chrX_100292062_ENST00000372931_length(amino acids)=1377AA_BP=1028
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQL
DENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT
HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISV
KVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH
HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKE
IADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA
FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGI
CSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE
THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGD
IWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM
LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKL
KSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKH
SQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTR
CSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQA
VEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIERSLIL

--------------------------------------------------------------
>35948_35948_3_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366581_TRMT2B_chrX_100292062_ENST00000372935_length(transcript)=5315nt_BP=3199nt
GAGGGTTGGGCTCCTTGGTACCATGTGGGAAGCGCTGTGAAGAGTTGTTGCCTTCCAAGATATACCCAAATTCCCAGTTCCAGCCCGTGT
CATTAAAACTCCGCTGGCGTGAAAGATGACGTCCTTAGCCCAGCAGCTGCAACGACTCGCCCTCCCTCAAAGTGATGCCAGCCTCTTATC
TAGAGATGAAGTTGCTTCTTTGTTATTTGACCCTAAGGAAGCGGCCACAATCGACAGGGACACCGCCTTCGCCATTGGATGTACTGGCCT
GGAAGAGTTGCTTGGAATTGATCCTTCCTTTGAGCAGTTTGAAGCACCGTTGTTCAGTCAGCTAGCAAAAACCTTGGAGCGAAGTGTTCA
GACCAAAGCAGTAAACAAACAGTTGGATGAAAACATTTCATTATTCCTTATTCACTTGTCGCCTTACTTCCTGCTTAAGCCAGCACAGAA
GTGTCTGGAGTGGTTGATTCACAGGTTCCATATACATCTCTATAATCAAGATAGCCTCATTGCTTGTGTTCTGCCATACCACGAGACAAG
AATATTTGTGCGAGTCATACAGCTTCTAAAAATTAATAATTCAAAGCACAGATGGTTCTGGTTGTTGCCAGTTAAGCAATCTGGAGTGCC
GTTAGCTAAAGGAACTTTGATTACCCACTGCTACAAAGATCTTGGATTCATGGATTTCATTTGCAGTTTGGTGACAAAATCTGTGAAGGT
TTTTGCTGAGTACCCGGGCAGCTCAGCTCAGTTGAGGGTGCTCTTGGCTTTCTATGCTTCTACCATAGTGTCGGCGCTGGTAGCTGCAGA
GGACGTATCAGACAATATCATCGCCAAACTATTTCCCTATATCCAAAAGGGATTGAAATCATCTTTACCAGATTACAGAGCTGCAACATA
CATGATAATATGTCAGATTTCTGTGAAAGTGACCATGGAAAATACCTTTGTGAATTCATTGGCATCACAGATCATCAAAACATTGACCAA
GATTCCCTCTTTGATCAAGGATGGGTTAAGTTGCTTGATAGTGCTCCTGCAGAGACAGAAGCCAGAGAGCCTTGGGAAAAAGCCATTCCC
TCACTTATGTAATGTTCCTGATCTTATTACAATACTTCATGGGATTTCTGAAACTTACGATGTCAGTCCTCTTCTGCATTACATGCTTCC
CCATCTGGTCGTCTCCATCATTCATCATGTTACAGGAGAAGAAACTGAAGGAATGGATGGTCAAATCTACAAGAGACACTTAGAAGCTAT
ACTTACAAAAATATCACTGAAGAACAACTTAGACCATTTGTTGGCTAGCCTTCTATTTGAAGAGTATATTTCATATAGTTCACAGGAAGA
AATGGATTCTAATAAAGTGTCTTTGCTTAATGAACAATTTCTTCCACTCATTAGGCTTTTAGAAAGCAAATACCCCAGAACATTAGATGT
TGTATTAGAGGAACACTTAAAGGAAATTGCAGATCTGAAAAAACAAGAGCTTTTCCATCAGTTTGTTTCTCTTTCTACAAGTGGAGGAAA
GTATCAGTTTTTAGCAGATTCTGATACTTCTTTGATGCTCAGCCTGAATCATCCACTTGCTCCTGTGAGAATTCTGGCCATGAATCATTT
GAAAAAGATCATGAAAACATCAAAGGAGGGTGTTGATGAATCTTTCATAAAAGAAGCTGTTTTAGCCCGATTAGGTGATGATAATATAGA
TGTTGTTTTGTCGGCTATAAGTGCTTTTGAGATTTTCAAAGAACACTTCAGTTCAGAAGTGACGATTTCAAATCTTCTGAATCTCTTTCA
AAGAGCAGAACTTTCAAAGAATGGAGAATGGTACGAGGTACTTAAGATAGCCGCTGACATATTAATTAAAGAAGAGATACTGAGTGAAAA
TGATCAGTTGTCAAATCAGGTGGTTGTATGTTTGCTGCCATTTATGGTTATCAATAATGATGATACGGAATCTGCTGAGATGAAAATTGC
TATATATTTATCAAAATCAGGAATCTGCTCCCTGCACCCTCTATTAAGAGGCTGGGAAGAAGCTCTTGAAAATGTAATTAAAAGCACAAA
GCCAGGAAAACTAATCGGTGTAGCAAATCAGAAGATGATTGAGTTGTTGGCTGATAATATAAATTTAGGAGATCCTTCTTCAATGTTAAA
GATGGTGGAGGATTTAATAAGCGTGGGTGAGGAGGAGTCCTTTAACCTGAAGCAGAAAGTAACGTTTCATGTGATCCTGTCTGTGCTCGT
CTCTTGTTGTTCATCTTTAAAAGAAACCCACTTTCCATTTGCGATAAGAGTCTTCAGTTTGTTGCAGAAAAAAATAAAGAAGCTTGAAAG
TGTCATTACTGCAGTGGAAATCCCCTCAGAATGGCACATTGAACTGATGTTAGACAGAGGGATCCCAGTGGAGCTGTGGGCACATTATGT
AGAAGAGCTCAACAGCACTCAGAGGGTGGCCGTGGAGGACTCGGTTTTTCTTGTATTTTCCTTGAAAAAATTTATTTATGCACTGAAAGC
TCCTAAATCTTTTCCTAAAGGTGATATATGGTGGAATCCTGAACAACTGAAAGAAGACAGCAGGGACTATCTGCACTTGCTCATTGGGCT
GTTTGAGATGATGCTCAATGGTGCCGATGCTGTTCATTTCAGAGTTCTGATGAAACTTTTCATAAAGGTGCATCTAGAAGATGTTTTTCA
GTTATTCAAGTTCTGTTCTGTTTTATGGACCTATGGTTCTAGCCTTTCAAATCCACTAAACTGCAGTGTGAAAACAGTGCTGCAGACTCA
AGCTCTTTATGTGGGCTGTGCAATGCTTTCTTCTCAGAAGACACAGTGTAAACACCAACTGGCATCCATATCTTCTCCAGTGGTGACATC
TTTACTCATTAACCTGGGAAGCCCCGTAAAAGAAGTTCGTAGGGCTGCCATTCAGTGTCTCCAGGCCCTCAGTGGAGTGGCATCCCCGTT
TTATCTGATAATAGATCATTTGATTTCTAAAGCAGAGGAGATCACTTCAGATGCTGCCTATGTTATTCAGGATTTGGCTACTTTATTTGA
GGAACTACAGAGAGAAAAGAAACTGAAATCTCATCAGAAGTTGTCTGAAACTTTGAAAAACTTACTTAGTTGTGTGTATAGTTGCCCATC
TTATATAGCAAAAGATTTGATGAAAGTACTTCAGGGAGTCAACGGTGAGCCTGTCATCAATGGTTACCGAAATAAGTCCACCTTCTCTGT
GAACCGAGGTCCAGATGGCAATCCAAAGACTGTGGGGTTCTACCTGGGAACTTGGAGAGATGGGAACGTTGTCTGTGTGCAGTCTAATCA
TCTGAAAAACATCCCTGAGAAACACAGTCAAGTGGCGCAGTACTATGAAGTATTCCTTCGACAGTCTCCATTGGAGCCCTGCCTTGTATT
TCATGAAGGTGGATACTGGCGTGAGCTCACAGTCCGCACCAATAGCCAAGGGCACACAATGGCTATCATCACTTTCCATCCCCAGAAATT
AAGTCAGGAGGAGCTCCATGTTCAGAAGGAGATTGTAAAGGAATTTTTCATCAGAGGTCCTGGAGCAGCCTGTGGCTTGACCTCACTTTA
CTTCCAGGAAAGTACCATGACCCGTTGCAGCCATCAGCAGTCTCCCTATCAGCTTCTGTTTGGGGAACCCTACATCTTTGAAGAACTTCT
GAGCTTGAAGATCCGCATCTCTCCAGATGCCTTTTTCCAGATTAACACAGCTGGTGCAGAGATGCTGTATCGGACTGTGGGGGAGCTGAC
TGGAGTGAACTCTGACACCATCCTTCTTGACATCTGCTGTGGAACTGGTGTGATTGGCCTCTCTCTGGCTCAGCATACATCTCGGGTCCT
TGGGATTGAATTGTTGGAGCAGGCAGTGGAGGATGCAAGATGGACTGCAGCCTTCAATGGCATCACCAACTCTGAATTTCATACTGGTCA
AGCAGAGAAGATTTTGCCAGGGCTGCTAAAGTCAAAGGAAGATGGACAGTCAATTGTTGCTGTGGTGAACCCAGCCCGTGCCGGACTGCA
TTACAAGGTGATTCAAGCCATTCGAAACTTCAGGGCCATCCACACGCTAGTTTTTGTTTCCTGCAAGCTCCATGGTGAATCCACTAGGAA
TGTCATTGAGCTGTGCTGTCCTCCAGACCCTGCTAAGAAGCTCTTAGGCGAGCCCTTTGTCCTGCAGCAAGCTGTACCTGTGGATTTGTT
CCCTCACACCCCACATTGTGAGCTGGTGCTCCTCTTTACTCGATAAGCAGCCTCCTAGAAGACAGCAGGCTATTTGTTAAGGCTGAAGTT
TCAGAAACTTTCAGGTTTGGCATATTGCTACATTGCAGACCCTGGGAGCATTACAGTGGAAACCAATCTTTGGTTTGTGAATAGGAAGAA
TCTATTAGGCCTCTGGTCTGAGGCAGATTTTTTTTTTGAGATAGAGTCTCACTCTTGCCCAGGCTGGAGTGTCGTGGCGTGATCTCAGCT
CACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCTTCCCCAGTAGCTAGGATTAAAGGTGCGTGCCACCATGCCCGG
CTAATTTTTGTATTTTTGGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCGCCTCG
GCCTCTCAAAGTGCTGGGATTATAGGCGTGAGCCACCACACCCCGCCGCGGCTGACTTAACCTTAGATTTCAGATTCCCTTTCAATCATG
CCCGTTTGCTTGGGTTTGACCACTCCCCACTCCTGGATCTGGACTGTTTCTTCCTGTTGCTGTCAGCCTTGGTTCTAGTTTATAGTCTTG
TCTCCTCCGTTTCTGCTTATGGTGTGGACAAATGACCTTTTTTAAGCAGCTGGTAATAATTTTACATTGACTGGAGCCTGTGCATTTGCT
CAGAGATGCTACAATTTTTAGATATTTCTAAGACTTCTGGATTCTTGAGGTAGTTAAGGATTAAAACCAGAAACAGTCGAGGTTTTTTAA
AAGCAGGGTAAGCCATGAAGTGAATACAGGGTGACTGAGTGATCATCAGATGAGATTAATTCTTTTGGGTTTTCTTGGTTTTAAGGCATC
TCGAATGCCCCTTGAAAATGTAGTTTTCCCTGGTGGTGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATAATTGCTTGAA
CCTGGGAGGTGGAGGTTGCAGTGAGCTGAAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACACCATCTCAAAAAAAAAAAA

>35948_35948_3_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366581_TRMT2B_chrX_100292062_ENST00000372935_length(amino acids)=1386AA_BP=1028
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQL
DENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT
HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISV
KVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH
HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKE
IADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA
FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGI
CSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE
THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGD
IWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM
LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKL
KSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKH
SQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTR
CSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQA
VEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPP

--------------------------------------------------------------
>35948_35948_4_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366581_TRMT2B_chrX_100292062_ENST00000372936_length(transcript)=5315nt_BP=3199nt
GAGGGTTGGGCTCCTTGGTACCATGTGGGAAGCGCTGTGAAGAGTTGTTGCCTTCCAAGATATACCCAAATTCCCAGTTCCAGCCCGTGT
CATTAAAACTCCGCTGGCGTGAAAGATGACGTCCTTAGCCCAGCAGCTGCAACGACTCGCCCTCCCTCAAAGTGATGCCAGCCTCTTATC
TAGAGATGAAGTTGCTTCTTTGTTATTTGACCCTAAGGAAGCGGCCACAATCGACAGGGACACCGCCTTCGCCATTGGATGTACTGGCCT
GGAAGAGTTGCTTGGAATTGATCCTTCCTTTGAGCAGTTTGAAGCACCGTTGTTCAGTCAGCTAGCAAAAACCTTGGAGCGAAGTGTTCA
GACCAAAGCAGTAAACAAACAGTTGGATGAAAACATTTCATTATTCCTTATTCACTTGTCGCCTTACTTCCTGCTTAAGCCAGCACAGAA
GTGTCTGGAGTGGTTGATTCACAGGTTCCATATACATCTCTATAATCAAGATAGCCTCATTGCTTGTGTTCTGCCATACCACGAGACAAG
AATATTTGTGCGAGTCATACAGCTTCTAAAAATTAATAATTCAAAGCACAGATGGTTCTGGTTGTTGCCAGTTAAGCAATCTGGAGTGCC
GTTAGCTAAAGGAACTTTGATTACCCACTGCTACAAAGATCTTGGATTCATGGATTTCATTTGCAGTTTGGTGACAAAATCTGTGAAGGT
TTTTGCTGAGTACCCGGGCAGCTCAGCTCAGTTGAGGGTGCTCTTGGCTTTCTATGCTTCTACCATAGTGTCGGCGCTGGTAGCTGCAGA
GGACGTATCAGACAATATCATCGCCAAACTATTTCCCTATATCCAAAAGGGATTGAAATCATCTTTACCAGATTACAGAGCTGCAACATA
CATGATAATATGTCAGATTTCTGTGAAAGTGACCATGGAAAATACCTTTGTGAATTCATTGGCATCACAGATCATCAAAACATTGACCAA
GATTCCCTCTTTGATCAAGGATGGGTTAAGTTGCTTGATAGTGCTCCTGCAGAGACAGAAGCCAGAGAGCCTTGGGAAAAAGCCATTCCC
TCACTTATGTAATGTTCCTGATCTTATTACAATACTTCATGGGATTTCTGAAACTTACGATGTCAGTCCTCTTCTGCATTACATGCTTCC
CCATCTGGTCGTCTCCATCATTCATCATGTTACAGGAGAAGAAACTGAAGGAATGGATGGTCAAATCTACAAGAGACACTTAGAAGCTAT
ACTTACAAAAATATCACTGAAGAACAACTTAGACCATTTGTTGGCTAGCCTTCTATTTGAAGAGTATATTTCATATAGTTCACAGGAAGA
AATGGATTCTAATAAAGTGTCTTTGCTTAATGAACAATTTCTTCCACTCATTAGGCTTTTAGAAAGCAAATACCCCAGAACATTAGATGT
TGTATTAGAGGAACACTTAAAGGAAATTGCAGATCTGAAAAAACAAGAGCTTTTCCATCAGTTTGTTTCTCTTTCTACAAGTGGAGGAAA
GTATCAGTTTTTAGCAGATTCTGATACTTCTTTGATGCTCAGCCTGAATCATCCACTTGCTCCTGTGAGAATTCTGGCCATGAATCATTT
GAAAAAGATCATGAAAACATCAAAGGAGGGTGTTGATGAATCTTTCATAAAAGAAGCTGTTTTAGCCCGATTAGGTGATGATAATATAGA
TGTTGTTTTGTCGGCTATAAGTGCTTTTGAGATTTTCAAAGAACACTTCAGTTCAGAAGTGACGATTTCAAATCTTCTGAATCTCTTTCA
AAGAGCAGAACTTTCAAAGAATGGAGAATGGTACGAGGTACTTAAGATAGCCGCTGACATATTAATTAAAGAAGAGATACTGAGTGAAAA
TGATCAGTTGTCAAATCAGGTGGTTGTATGTTTGCTGCCATTTATGGTTATCAATAATGATGATACGGAATCTGCTGAGATGAAAATTGC
TATATATTTATCAAAATCAGGAATCTGCTCCCTGCACCCTCTATTAAGAGGCTGGGAAGAAGCTCTTGAAAATGTAATTAAAAGCACAAA
GCCAGGAAAACTAATCGGTGTAGCAAATCAGAAGATGATTGAGTTGTTGGCTGATAATATAAATTTAGGAGATCCTTCTTCAATGTTAAA
GATGGTGGAGGATTTAATAAGCGTGGGTGAGGAGGAGTCCTTTAACCTGAAGCAGAAAGTAACGTTTCATGTGATCCTGTCTGTGCTCGT
CTCTTGTTGTTCATCTTTAAAAGAAACCCACTTTCCATTTGCGATAAGAGTCTTCAGTTTGTTGCAGAAAAAAATAAAGAAGCTTGAAAG
TGTCATTACTGCAGTGGAAATCCCCTCAGAATGGCACATTGAACTGATGTTAGACAGAGGGATCCCAGTGGAGCTGTGGGCACATTATGT
AGAAGAGCTCAACAGCACTCAGAGGGTGGCCGTGGAGGACTCGGTTTTTCTTGTATTTTCCTTGAAAAAATTTATTTATGCACTGAAAGC
TCCTAAATCTTTTCCTAAAGGTGATATATGGTGGAATCCTGAACAACTGAAAGAAGACAGCAGGGACTATCTGCACTTGCTCATTGGGCT
GTTTGAGATGATGCTCAATGGTGCCGATGCTGTTCATTTCAGAGTTCTGATGAAACTTTTCATAAAGGTGCATCTAGAAGATGTTTTTCA
GTTATTCAAGTTCTGTTCTGTTTTATGGACCTATGGTTCTAGCCTTTCAAATCCACTAAACTGCAGTGTGAAAACAGTGCTGCAGACTCA
AGCTCTTTATGTGGGCTGTGCAATGCTTTCTTCTCAGAAGACACAGTGTAAACACCAACTGGCATCCATATCTTCTCCAGTGGTGACATC
TTTACTCATTAACCTGGGAAGCCCCGTAAAAGAAGTTCGTAGGGCTGCCATTCAGTGTCTCCAGGCCCTCAGTGGAGTGGCATCCCCGTT
TTATCTGATAATAGATCATTTGATTTCTAAAGCAGAGGAGATCACTTCAGATGCTGCCTATGTTATTCAGGATTTGGCTACTTTATTTGA
GGAACTACAGAGAGAAAAGAAACTGAAATCTCATCAGAAGTTGTCTGAAACTTTGAAAAACTTACTTAGTTGTGTGTATAGTTGCCCATC
TTATATAGCAAAAGATTTGATGAAAGTACTTCAGGGAGTCAACGGTGAGCCTGTCATCAATGGTTACCGAAATAAGTCCACCTTCTCTGT
GAACCGAGGTCCAGATGGCAATCCAAAGACTGTGGGGTTCTACCTGGGAACTTGGAGAGATGGGAACGTTGTCTGTGTGCAGTCTAATCA
TCTGAAAAACATCCCTGAGAAACACAGTCAAGTGGCGCAGTACTATGAAGTATTCCTTCGACAGTCTCCATTGGAGCCCTGCCTTGTATT
TCATGAAGGTGGATACTGGCGTGAGCTCACAGTCCGCACCAATAGCCAAGGGCACACAATGGCTATCATCACTTTCCATCCCCAGAAATT
AAGTCAGGAGGAGCTCCATGTTCAGAAGGAGATTGTAAAGGAATTTTTCATCAGAGGTCCTGGAGCAGCCTGTGGCTTGACCTCACTTTA
CTTCCAGGAAAGTACCATGACCCGTTGCAGCCATCAGCAGTCTCCCTATCAGCTTCTGTTTGGGGAACCCTACATCTTTGAAGAACTTCT
GAGCTTGAAGATCCGCATCTCTCCAGATGCCTTTTTCCAGATTAACACAGCTGGTGCAGAGATGCTGTATCGGACTGTGGGGGAGCTGAC
TGGAGTGAACTCTGACACCATCCTTCTTGACATCTGCTGTGGAACTGGTGTGATTGGCCTCTCTCTGGCTCAGCATACATCTCGGGTCCT
TGGGATTGAATTGTTGGAGCAGGCAGTGGAGGATGCAAGATGGACTGCAGCCTTCAATGGCATCACCAACTCTGAATTTCATACTGGTCA
AGCAGAGAAGATTTTGCCAGGGCTGCTAAAGTCAAAGGAAGATGGACAGTCAATTGTTGCTGTGGTGAACCCAGCCCGTGCCGGACTGCA
TTACAAGGTGATTCAAGCCATTCGAAACTTCAGGGCCATCCACACGCTAGTTTTTGTTTCCTGCAAGCTCCATGGTGAATCCACTAGGAA
TGTCATTGAGCTGTGCTGTCCTCCAGACCCTGCTAAGAAGCTCTTAGGCGAGCCCTTTGTCCTGCAGCAAGCTGTACCTGTGGATTTGTT
CCCTCACACCCCACATTGTGAGCTGGTGCTCCTCTTTACTCGATAAGCAGCCTCCTAGAAGACAGCAGGCTATTTGTTAAGGCTGAAGTT
TCAGAAACTTTCAGGTTTGGCATATTGCTACATTGCAGACCCTGGGAGCATTACAGTGGAAACCAATCTTTGGTTTGTGAATAGGAAGAA
TCTATTAGGCCTCTGGTCTGAGGCAGATTTTTTTTTTGAGATAGAGTCTCACTCTTGCCCAGGCTGGAGTGTCGTGGCGTGATCTCAGCT
CACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCTTCCCCAGTAGCTAGGATTAAAGGTGCGTGCCACCATGCCCGG
CTAATTTTTGTATTTTTGGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCGCCTCG
GCCTCTCAAAGTGCTGGGATTATAGGCGTGAGCCACCACACCCCGCCGCGGCTGACTTAACCTTAGATTTCAGATTCCCTTTCAATCATG
CCCGTTTGCTTGGGTTTGACCACTCCCCACTCCTGGATCTGGACTGTTTCTTCCTGTTGCTGTCAGCCTTGGTTCTAGTTTATAGTCTTG
TCTCCTCCGTTTCTGCTTATGGTGTGGACAAATGACCTTTTTTAAGCAGCTGGTAATAATTTTACATTGACTGGAGCCTGTGCATTTGCT
CAGAGATGCTACAATTTTTAGATATTTCTAAGACTTCTGGATTCTTGAGGTAGTTAAGGATTAAAACCAGAAACAGTCGAGGTTTTTTAA
AAGCAGGGTAAGCCATGAAGTGAATACAGGGTGACTGAGTGATCATCAGATGAGATTAATTCTTTTGGGTTTTCTTGGTTTTAAGGCATC
TCGAATGCCCCTTGAAAATGTAGTTTTCCCTGGTGGTGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATAATTGCTTGAA
CCTGGGAGGTGGAGGTTGCAGTGAGCTGAAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACACCATCTCAAAAAAAAAAAA

>35948_35948_4_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366581_TRMT2B_chrX_100292062_ENST00000372936_length(amino acids)=1386AA_BP=1028
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQL
DENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT
HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISV
KVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH
HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKE
IADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA
FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGI
CSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE
THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGD
IWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM
LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKL
KSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKH
SQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTR
CSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQA
VEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPP

--------------------------------------------------------------
>35948_35948_5_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366581_TRMT2B_chrX_100292062_ENST00000372939_length(transcript)=5507nt_BP=3199nt
GAGGGTTGGGCTCCTTGGTACCATGTGGGAAGCGCTGTGAAGAGTTGTTGCCTTCCAAGATATACCCAAATTCCCAGTTCCAGCCCGTGT
CATTAAAACTCCGCTGGCGTGAAAGATGACGTCCTTAGCCCAGCAGCTGCAACGACTCGCCCTCCCTCAAAGTGATGCCAGCCTCTTATC
TAGAGATGAAGTTGCTTCTTTGTTATTTGACCCTAAGGAAGCGGCCACAATCGACAGGGACACCGCCTTCGCCATTGGATGTACTGGCCT
GGAAGAGTTGCTTGGAATTGATCCTTCCTTTGAGCAGTTTGAAGCACCGTTGTTCAGTCAGCTAGCAAAAACCTTGGAGCGAAGTGTTCA
GACCAAAGCAGTAAACAAACAGTTGGATGAAAACATTTCATTATTCCTTATTCACTTGTCGCCTTACTTCCTGCTTAAGCCAGCACAGAA
GTGTCTGGAGTGGTTGATTCACAGGTTCCATATACATCTCTATAATCAAGATAGCCTCATTGCTTGTGTTCTGCCATACCACGAGACAAG
AATATTTGTGCGAGTCATACAGCTTCTAAAAATTAATAATTCAAAGCACAGATGGTTCTGGTTGTTGCCAGTTAAGCAATCTGGAGTGCC
GTTAGCTAAAGGAACTTTGATTACCCACTGCTACAAAGATCTTGGATTCATGGATTTCATTTGCAGTTTGGTGACAAAATCTGTGAAGGT
TTTTGCTGAGTACCCGGGCAGCTCAGCTCAGTTGAGGGTGCTCTTGGCTTTCTATGCTTCTACCATAGTGTCGGCGCTGGTAGCTGCAGA
GGACGTATCAGACAATATCATCGCCAAACTATTTCCCTATATCCAAAAGGGATTGAAATCATCTTTACCAGATTACAGAGCTGCAACATA
CATGATAATATGTCAGATTTCTGTGAAAGTGACCATGGAAAATACCTTTGTGAATTCATTGGCATCACAGATCATCAAAACATTGACCAA
GATTCCCTCTTTGATCAAGGATGGGTTAAGTTGCTTGATAGTGCTCCTGCAGAGACAGAAGCCAGAGAGCCTTGGGAAAAAGCCATTCCC
TCACTTATGTAATGTTCCTGATCTTATTACAATACTTCATGGGATTTCTGAAACTTACGATGTCAGTCCTCTTCTGCATTACATGCTTCC
CCATCTGGTCGTCTCCATCATTCATCATGTTACAGGAGAAGAAACTGAAGGAATGGATGGTCAAATCTACAAGAGACACTTAGAAGCTAT
ACTTACAAAAATATCACTGAAGAACAACTTAGACCATTTGTTGGCTAGCCTTCTATTTGAAGAGTATATTTCATATAGTTCACAGGAAGA
AATGGATTCTAATAAAGTGTCTTTGCTTAATGAACAATTTCTTCCACTCATTAGGCTTTTAGAAAGCAAATACCCCAGAACATTAGATGT
TGTATTAGAGGAACACTTAAAGGAAATTGCAGATCTGAAAAAACAAGAGCTTTTCCATCAGTTTGTTTCTCTTTCTACAAGTGGAGGAAA
GTATCAGTTTTTAGCAGATTCTGATACTTCTTTGATGCTCAGCCTGAATCATCCACTTGCTCCTGTGAGAATTCTGGCCATGAATCATTT
GAAAAAGATCATGAAAACATCAAAGGAGGGTGTTGATGAATCTTTCATAAAAGAAGCTGTTTTAGCCCGATTAGGTGATGATAATATAGA
TGTTGTTTTGTCGGCTATAAGTGCTTTTGAGATTTTCAAAGAACACTTCAGTTCAGAAGTGACGATTTCAAATCTTCTGAATCTCTTTCA
AAGAGCAGAACTTTCAAAGAATGGAGAATGGTACGAGGTACTTAAGATAGCCGCTGACATATTAATTAAAGAAGAGATACTGAGTGAAAA
TGATCAGTTGTCAAATCAGGTGGTTGTATGTTTGCTGCCATTTATGGTTATCAATAATGATGATACGGAATCTGCTGAGATGAAAATTGC
TATATATTTATCAAAATCAGGAATCTGCTCCCTGCACCCTCTATTAAGAGGCTGGGAAGAAGCTCTTGAAAATGTAATTAAAAGCACAAA
GCCAGGAAAACTAATCGGTGTAGCAAATCAGAAGATGATTGAGTTGTTGGCTGATAATATAAATTTAGGAGATCCTTCTTCAATGTTAAA
GATGGTGGAGGATTTAATAAGCGTGGGTGAGGAGGAGTCCTTTAACCTGAAGCAGAAAGTAACGTTTCATGTGATCCTGTCTGTGCTCGT
CTCTTGTTGTTCATCTTTAAAAGAAACCCACTTTCCATTTGCGATAAGAGTCTTCAGTTTGTTGCAGAAAAAAATAAAGAAGCTTGAAAG
TGTCATTACTGCAGTGGAAATCCCCTCAGAATGGCACATTGAACTGATGTTAGACAGAGGGATCCCAGTGGAGCTGTGGGCACATTATGT
AGAAGAGCTCAACAGCACTCAGAGGGTGGCCGTGGAGGACTCGGTTTTTCTTGTATTTTCCTTGAAAAAATTTATTTATGCACTGAAAGC
TCCTAAATCTTTTCCTAAAGGTGATATATGGTGGAATCCTGAACAACTGAAAGAAGACAGCAGGGACTATCTGCACTTGCTCATTGGGCT
GTTTGAGATGATGCTCAATGGTGCCGATGCTGTTCATTTCAGAGTTCTGATGAAACTTTTCATAAAGGTGCATCTAGAAGATGTTTTTCA
GTTATTCAAGTTCTGTTCTGTTTTATGGACCTATGGTTCTAGCCTTTCAAATCCACTAAACTGCAGTGTGAAAACAGTGCTGCAGACTCA
AGCTCTTTATGTGGGCTGTGCAATGCTTTCTTCTCAGAAGACACAGTGTAAACACCAACTGGCATCCATATCTTCTCCAGTGGTGACATC
TTTACTCATTAACCTGGGAAGCCCCGTAAAAGAAGTTCGTAGGGCTGCCATTCAGTGTCTCCAGGCCCTCAGTGGAGTGGCATCCCCGTT
TTATCTGATAATAGATCATTTGATTTCTAAAGCAGAGGAGATCACTTCAGATGCTGCCTATGTTATTCAGGATTTGGCTACTTTATTTGA
GGAACTACAGAGAGAAAAGAAACTGAAATCTCATCAGAAGTTGTCTGAAACTTTGAAAAACTTACTTAGTTGTGTGTATAGTTGCCCATC
TTATATAGCAAAAGATTTGATGAAAGTACTTCAGGGAGTCAACGGTGAGCCTGTCATCAATGGTTACCGAAATAAGTCCACCTTCTCTGT
GAACCGAGGTCCAGATGGCAATCCAAAGACTGTGGGGTTCTACCTGGGAACTTGGAGAGATGGGAACGTTGTCTGTGTGCAGTCTAATCA
TCTGAAAAACATCCCTGAGAAACACAGTCAAGTGGCGCAGTACTATGAAGTATTCCTTCGACAGTCTCCATTGGAGCCCTGCCTTGTATT
TCATGAAGGTGGATACTGGCGTGAGCTCACAGTCCGCACCAATAGCCAAGGGCACACAATGGCTATCATCACTTTCCATCCCCAGAAATT
AAGTCAGGAGGAGCTCCATGTTCAGAAGGAGATTGTAAAGGAATTTTTCATCAGAGGTCCTGGAGCAGCCTGTGGCTTGACCTCACTTTA
CTTCCAGGAAAGTACCATGACCCGTTGCAGCCATCAGCAGTCTCCCTATCAGCTTCTGTTTGGGGAACCCTACATCTTTGAAGAACTTCT
GAGCTTGAAGATCCGCATCTCTCCAGATGCCTTTTTCCAGATTAACACAGCTGGTGCAGAGATGCTGTATCGGACTGTGGGGGAGCTGAC
TGGAGTGAACTCTGACACCATCCTTCTTGACATCTGCTGTGGAACTGGTGTGATTGGCCTCTCTCTGGCTCAGCATACATCTCGGGTCCT
TGGGATTGAATTGTTGGAGCAGGCAGTGGAGGATGCAAGATGGACTGCAGCCTTCAATGGCATCACCAACTCTGAATTTCATACTGGTCA
AGCAGAGAAGATTTTGCCAGGGCTGCTAAAGTCAAAGGAAGATGGACAGTCAATTGTTGCTGTGGTGAACCCAGCCCGTGCCGGACTGCA
TTACAAGGTGATTCAAGCCATTCGAAACTTCAGGGCCATCCACACGCTAGTTTTTGTTTCCTGCAAGCTCCATGGTGAATCCACTAGGAA
TGTCATTGAGCTGTGCTGTCCTCCAGACCCTGCTAAGAAGCTCTTAGGCGAGCCCTTTGTCCTGCAGCAAGCTGTACCTGTGGATTTGTT
CCCTCACACCCCACATTGTGAGCTGGTGCTCCTCTTTACTCGATAAGCAGCCTCCTAGAAGACAGCAGGCTATTTGTTAAGGCTGAAGTT
TCAGAAACTTTCAGGTTTGGCATATTGCTACATTGCAGACCCTGGGAGCATTACAGTGGAAACCAATCTTTGGTTTGTGAATAGGAAGAA
TCTATTAGGCCTCTGGTCTGAGGCAGATTTTTTTTTTGAGATAGAGTCTCACTCTTGCCCAGGCTGGAGTGTCGTGGCGTGATCTCAGCT
CACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCTTCCCCAGTAGCTAGGATTAAAGGTGCGTGCCACCATGCCCGG
CTAATTTTTGTATTTTTGGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCGCCTCG
GCCTCTCAAAGTGCTGGGATTATAGGCGTGAGCCACCACACCCCGCCGCGGCTGACTTAACCTTAGATTTCAGATTCCCTTTCAATCATG
CCCGTTTGCTTGGGTTTGACCACTCCCCACTCCTGGATCTGGACTGTTTCTTCCTGTTGCTGTCAGCCTTGGTTCTAGTTTATAGTCTTG
TCTCCTCCGTTTCTGCTTATGGTGTGGACAAATGACCTTTTTTAAGCAGCTGGTAATAATTTTACATTGACTGGAGCCTGTGCATTTGCT
CAGAGATGCTACAATTTTTAGATATTTCTAAGACTTCTGGATTCTTGAGGTAGTTAAGGATTAAAACCAGAAACAGTCGAGGTTTTTTAA
AAGCAGGGTAAGCCATGAAGTGAATACAGGGTGACTGAGTGATCATCAGATGAGATTAATTCTTTTGGGTTTTCTTGGTTTTAAGGCATC
TCGAATGCCCCTTGAAAATGTAGTTTTCCCTGGTGGTGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATAATTGCTTGAA
CCTGGGAGGTGGAGGTTGCAGTGAGCTGAAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACACCATCTCAAAAAAAAAAAA
AAAAAGAAAATGTAGTTATCCCTAGGAGCAATAGCACCAATTAACTCTCACCCGTGGAGGAAGAATTGGTTATTGGAGAGACCCTAAGGG
AAAGGAGATTTTCAGAGAGACTGAATACCTATAATTGTGCTGTGTAGTGTGGAGGCAAAAAGCTCCAAAATCTAGTATAACATAATAAAC

>35948_35948_5_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366581_TRMT2B_chrX_100292062_ENST00000372939_length(amino acids)=1386AA_BP=1028
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQL
DENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT
HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISV
KVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH
HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKE
IADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA
FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGI
CSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE
THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGD
IWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM
LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKL
KSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKH
SQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTR
CSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQA
VEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPP

--------------------------------------------------------------
>35948_35948_6_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366581_TRMT2B_chrX_100292062_ENST00000545398_length(transcript)=5511nt_BP=3199nt
GAGGGTTGGGCTCCTTGGTACCATGTGGGAAGCGCTGTGAAGAGTTGTTGCCTTCCAAGATATACCCAAATTCCCAGTTCCAGCCCGTGT
CATTAAAACTCCGCTGGCGTGAAAGATGACGTCCTTAGCCCAGCAGCTGCAACGACTCGCCCTCCCTCAAAGTGATGCCAGCCTCTTATC
TAGAGATGAAGTTGCTTCTTTGTTATTTGACCCTAAGGAAGCGGCCACAATCGACAGGGACACCGCCTTCGCCATTGGATGTACTGGCCT
GGAAGAGTTGCTTGGAATTGATCCTTCCTTTGAGCAGTTTGAAGCACCGTTGTTCAGTCAGCTAGCAAAAACCTTGGAGCGAAGTGTTCA
GACCAAAGCAGTAAACAAACAGTTGGATGAAAACATTTCATTATTCCTTATTCACTTGTCGCCTTACTTCCTGCTTAAGCCAGCACAGAA
GTGTCTGGAGTGGTTGATTCACAGGTTCCATATACATCTCTATAATCAAGATAGCCTCATTGCTTGTGTTCTGCCATACCACGAGACAAG
AATATTTGTGCGAGTCATACAGCTTCTAAAAATTAATAATTCAAAGCACAGATGGTTCTGGTTGTTGCCAGTTAAGCAATCTGGAGTGCC
GTTAGCTAAAGGAACTTTGATTACCCACTGCTACAAAGATCTTGGATTCATGGATTTCATTTGCAGTTTGGTGACAAAATCTGTGAAGGT
TTTTGCTGAGTACCCGGGCAGCTCAGCTCAGTTGAGGGTGCTCTTGGCTTTCTATGCTTCTACCATAGTGTCGGCGCTGGTAGCTGCAGA
GGACGTATCAGACAATATCATCGCCAAACTATTTCCCTATATCCAAAAGGGATTGAAATCATCTTTACCAGATTACAGAGCTGCAACATA
CATGATAATATGTCAGATTTCTGTGAAAGTGACCATGGAAAATACCTTTGTGAATTCATTGGCATCACAGATCATCAAAACATTGACCAA
GATTCCCTCTTTGATCAAGGATGGGTTAAGTTGCTTGATAGTGCTCCTGCAGAGACAGAAGCCAGAGAGCCTTGGGAAAAAGCCATTCCC
TCACTTATGTAATGTTCCTGATCTTATTACAATACTTCATGGGATTTCTGAAACTTACGATGTCAGTCCTCTTCTGCATTACATGCTTCC
CCATCTGGTCGTCTCCATCATTCATCATGTTACAGGAGAAGAAACTGAAGGAATGGATGGTCAAATCTACAAGAGACACTTAGAAGCTAT
ACTTACAAAAATATCACTGAAGAACAACTTAGACCATTTGTTGGCTAGCCTTCTATTTGAAGAGTATATTTCATATAGTTCACAGGAAGA
AATGGATTCTAATAAAGTGTCTTTGCTTAATGAACAATTTCTTCCACTCATTAGGCTTTTAGAAAGCAAATACCCCAGAACATTAGATGT
TGTATTAGAGGAACACTTAAAGGAAATTGCAGATCTGAAAAAACAAGAGCTTTTCCATCAGTTTGTTTCTCTTTCTACAAGTGGAGGAAA
GTATCAGTTTTTAGCAGATTCTGATACTTCTTTGATGCTCAGCCTGAATCATCCACTTGCTCCTGTGAGAATTCTGGCCATGAATCATTT
GAAAAAGATCATGAAAACATCAAAGGAGGGTGTTGATGAATCTTTCATAAAAGAAGCTGTTTTAGCCCGATTAGGTGATGATAATATAGA
TGTTGTTTTGTCGGCTATAAGTGCTTTTGAGATTTTCAAAGAACACTTCAGTTCAGAAGTGACGATTTCAAATCTTCTGAATCTCTTTCA
AAGAGCAGAACTTTCAAAGAATGGAGAATGGTACGAGGTACTTAAGATAGCCGCTGACATATTAATTAAAGAAGAGATACTGAGTGAAAA
TGATCAGTTGTCAAATCAGGTGGTTGTATGTTTGCTGCCATTTATGGTTATCAATAATGATGATACGGAATCTGCTGAGATGAAAATTGC
TATATATTTATCAAAATCAGGAATCTGCTCCCTGCACCCTCTATTAAGAGGCTGGGAAGAAGCTCTTGAAAATGTAATTAAAAGCACAAA
GCCAGGAAAACTAATCGGTGTAGCAAATCAGAAGATGATTGAGTTGTTGGCTGATAATATAAATTTAGGAGATCCTTCTTCAATGTTAAA
GATGGTGGAGGATTTAATAAGCGTGGGTGAGGAGGAGTCCTTTAACCTGAAGCAGAAAGTAACGTTTCATGTGATCCTGTCTGTGCTCGT
CTCTTGTTGTTCATCTTTAAAAGAAACCCACTTTCCATTTGCGATAAGAGTCTTCAGTTTGTTGCAGAAAAAAATAAAGAAGCTTGAAAG
TGTCATTACTGCAGTGGAAATCCCCTCAGAATGGCACATTGAACTGATGTTAGACAGAGGGATCCCAGTGGAGCTGTGGGCACATTATGT
AGAAGAGCTCAACAGCACTCAGAGGGTGGCCGTGGAGGACTCGGTTTTTCTTGTATTTTCCTTGAAAAAATTTATTTATGCACTGAAAGC
TCCTAAATCTTTTCCTAAAGGTGATATATGGTGGAATCCTGAACAACTGAAAGAAGACAGCAGGGACTATCTGCACTTGCTCATTGGGCT
GTTTGAGATGATGCTCAATGGTGCCGATGCTGTTCATTTCAGAGTTCTGATGAAACTTTTCATAAAGGTGCATCTAGAAGATGTTTTTCA
GTTATTCAAGTTCTGTTCTGTTTTATGGACCTATGGTTCTAGCCTTTCAAATCCACTAAACTGCAGTGTGAAAACAGTGCTGCAGACTCA
AGCTCTTTATGTGGGCTGTGCAATGCTTTCTTCTCAGAAGACACAGTGTAAACACCAACTGGCATCCATATCTTCTCCAGTGGTGACATC
TTTACTCATTAACCTGGGAAGCCCCGTAAAAGAAGTTCGTAGGGCTGCCATTCAGTGTCTCCAGGCCCTCAGTGGAGTGGCATCCCCGTT
TTATCTGATAATAGATCATTTGATTTCTAAAGCAGAGGAGATCACTTCAGATGCTGCCTATGTTATTCAGGATTTGGCTACTTTATTTGA
GGAACTACAGAGAGAAAAGAAACTGAAATCTCATCAGAAGTTGTCTGAAACTTTGAAAAACTTACTTAGTTGTGTGTATAGTTGCCCATC
TTATATAGCAAAAGATTTGATGAAAGTACTTCAGGGAGTCAACGGTGAGCCTGTCATCAATGGTTACCGAAATAAGTCCACCTTCTCTGT
GAACCGAGGTCCAGATGGCAATCCAAAGACTGTGGGGTTCTACCTGGGAACTTGGAGAGATGGGAACGTTGTCTGTGTGCAGTCTAATCA
TCTGAAAAACATCCCTGAGAAACACAGTCAAGTGGCGCAGTACTATGAAGTATTCCTTCGACAGTCTCCATTGGAGCCCTGCCTTGTATT
TCATGAAGGTGGATACTGGCGTGAGCTCACAGTCCGCACCAATAGCCAAGGGCACACAATGGCTATCATCACTTTCCATCCCCAGAAATT
AAGTCAGGAGGAGCTCCATGTTCAGAAGGAGATTGTAAAGGAATTTTTCATCAGAGGTCCTGGAGCAGCCTGTGGCTTGACCTCACTTTA
CTTCCAGGAAAGTACCATGACCCGTTGCAGCCATCAGCAGTCTCCCTATCAGCTTCTGTTTGGGGAACCCTACATCTTTGAAGAACTTCT
GAGCTTGAAGATCCGCATCTCTCCAGATGCCTTTTTCCAGATTAACACAGCTGGTGCAGAGATGCTGTATCGGACTGTGGGGGAGCTGAC
TGGAGTGAACTCTGACACCATCCTTCTTGACATCTGCTGTGGAACTGGTGTGATTGGCCTCTCTCTGGCTCAGCATACATCTCGGGTCCT
TGGGATTGAATTGTTGGAGCAGGCAGTGGAGGATGCAAGATGGACTGCAGCCTTCAATGGCATCACCAACTCTGAATTTCATACTGGTCA
AGCAGAGAAGATTTTGCCAGGGCTGCTAAAGTCAAAGGAAGATGGACAGTCAATTGTTGCTGTGGTGAACCCAGCCCGTGCCGGACTGCA
TTACAAGGTGATTCAAGCCATTCGAAACTTCAGGGCCATCCACACGCTAGTTTTTGTTTCCTGCAAGCTCCATGGTGAATCCACTAGGAA
TGTCATTGAGCTGTGCTGTCCTCCAGACCCTGCTAAGAAGCTCTTAGGCGAGCCCTTTGTCCTGCAGCAAGCTGTACCTGTGGATTTGTT
CCCTCACACCCCACATTGTGAGCTGGTGCTCCTCTTTACTCGATAAGCAGCCTCCTAGAAGACAGCAGGCTATTTGTTAAGGCTGAAGTT
TCAGAAACTTTCAGGTTTGGCATATTGCTACATTGCAGACCCTGGGAGCATTACAGTGGAAACCAATCTTTGGTTTGTGAATAGGAAGAA
TCTATTAGGCCTCTGGTCTGAGGCAGATTTTTTTTTTGAGATAGAGTCTCACTCTTGCCCAGGCTGGAGTGTCGTGGCGTGATCTCAGCT
CACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCTTCCCCAGTAGCTAGGATTAAAGGTGCGTGCCACCATGCCCGG
CTAATTTTTGTATTTTTGGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCGCCTCG
GCCTCTCAAAGTGCTGGGATTATAGGCGTGAGCCACCACACCCCGCCGCGGCTGACTTAACCTTAGATTTCAGATTCCCTTTCAATCATG
CCCGTTTGCTTGGGTTTGACCACTCCCCACTCCTGGATCTGGACTGTTTCTTCCTGTTGCTGTCAGCCTTGGTTCTAGTTTATAGTCTTG
TCTCCTCCGTTTCTGCTTATGGTGTGGACAAATGACCTTTTTTAAGCAGCTGGTAATAATTTTACATTGACTGGAGCCTGTGCATTTGCT
CAGAGATGCTACAATTTTTAGATATTTCTAAGACTTCTGGATTCTTGAGGTAGTTAAGGATTAAAACCAGAAACAGTCGAGGTTTTTTAA
AAGCAGGGTAAGCCATGAAGTGAATACAGGGTGACTGAGTGATCATCAGATGAGATTAATTCTTTTGGGTTTTCTTGGTTTTAAGGCATC
TCGAATGCCCCTTGAAAATGTAGTTTTCCCTGGTGGTGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATAATTGCTTGAA
CCTGGGAGGTGGAGGTTGCAGTGAGCTGAAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACACCATCTCAAAAAAAAAAAA
AAAAAGAAAATGTAGTTATCCCTAGGAGCAATAGCACCAATTAACTCTCACCCGTGGAGGAAGAATTGGTTATTGGAGAGACCCTAAGGG
AAAGGAGATTTTCAGAGAGACTGAATACCTATAATTGTGCTGTGTAGTGTGGAGGCAAAAAGCTCCAAAATCTAGTATAACATAATAAAC

>35948_35948_6_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366581_TRMT2B_chrX_100292062_ENST00000545398_length(amino acids)=1386AA_BP=1028
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQL
DENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT
HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISV
KVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH
HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKE
IADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA
FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGI
CSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE
THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGD
IWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM
LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKL
KSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKH
SQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTR
CSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQA
VEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPP

--------------------------------------------------------------
>35948_35948_7_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366582_TRMT2B_chrX_100292062_ENST00000338687_length(transcript)=5511nt_BP=3199nt
GAGGGTTGGGCTCCTTGGTACCATGTGGGAAGCGCTGTGAAGAGTTGTTGCCTTCCAAGATATACCCAAATTCCCAGTTCCAGCCCGTGT
CATTAAAACTCCGCTGGCGTGAAAGATGACGTCCTTAGCCCAGCAGCTGCAACGACTCGCCCTCCCTCAAAGTGATGCCAGCCTCTTATC
TAGAGATGAAGTTGCTTCTTTGTTATTTGACCCTAAGGAAGCGGCCACAATCGACAGGGACACCGCCTTCGCCATTGGATGTACTGGCCT
GGAAGAGTTGCTTGGAATTGATCCTTCCTTTGAGCAGTTTGAAGCACCGTTGTTCAGTCAGCTAGCAAAAACCTTGGAGCGAAGTGTTCA
GACCAAAGCAGTAAACAAACAGTTGGATGAAAACATTTCATTATTCCTTATTCACTTGTCGCCTTACTTCCTGCTTAAGCCAGCACAGAA
GTGTCTGGAGTGGTTGATTCACAGGTTCCATATACATCTCTATAATCAAGATAGCCTCATTGCTTGTGTTCTGCCATACCACGAGACAAG
AATATTTGTGCGAGTCATACAGCTTCTAAAAATTAATAATTCAAAGCACAGATGGTTCTGGTTGTTGCCAGTTAAGCAATCTGGAGTGCC
GTTAGCTAAAGGAACTTTGATTACCCACTGCTACAAAGATCTTGGATTCATGGATTTCATTTGCAGTTTGGTGACAAAATCTGTGAAGGT
TTTTGCTGAGTACCCGGGCAGCTCAGCTCAGTTGAGGGTGCTCTTGGCTTTCTATGCTTCTACCATAGTGTCGGCGCTGGTAGCTGCAGA
GGACGTATCAGACAATATCATCGCCAAACTATTTCCCTATATCCAAAAGGGATTGAAATCATCTTTACCAGATTACAGAGCTGCAACATA
CATGATAATATGTCAGATTTCTGTGAAAGTGACCATGGAAAATACCTTTGTGAATTCATTGGCATCACAGATCATCAAAACATTGACCAA
GATTCCCTCTTTGATCAAGGATGGGTTAAGTTGCTTGATAGTGCTCCTGCAGAGACAGAAGCCAGAGAGCCTTGGGAAAAAGCCATTCCC
TCACTTATGTAATGTTCCTGATCTTATTACAATACTTCATGGGATTTCTGAAACTTACGATGTCAGTCCTCTTCTGCATTACATGCTTCC
CCATCTGGTCGTCTCCATCATTCATCATGTTACAGGAGAAGAAACTGAAGGAATGGATGGTCAAATCTACAAGAGACACTTAGAAGCTAT
ACTTACAAAAATATCACTGAAGAACAACTTAGACCATTTGTTGGCTAGCCTTCTATTTGAAGAGTATATTTCATATAGTTCACAGGAAGA
AATGGATTCTAATAAAGTGTCTTTGCTTAATGAACAATTTCTTCCACTCATTAGGCTTTTAGAAAGCAAATACCCCAGAACATTAGATGT
TGTATTAGAGGAACACTTAAAGGAAATTGCAGATCTGAAAAAACAAGAGCTTTTCCATCAGTTTGTTTCTCTTTCTACAAGTGGAGGAAA
GTATCAGTTTTTAGCAGATTCTGATACTTCTTTGATGCTCAGCCTGAATCATCCACTTGCTCCTGTGAGAATTCTGGCCATGAATCATTT
GAAAAAGATCATGAAAACATCAAAGGAGGGTGTTGATGAATCTTTCATAAAAGAAGCTGTTTTAGCCCGATTAGGTGATGATAATATAGA
TGTTGTTTTGTCGGCTATAAGTGCTTTTGAGATTTTCAAAGAACACTTCAGTTCAGAAGTGACGATTTCAAATCTTCTGAATCTCTTTCA
AAGAGCAGAACTTTCAAAGAATGGAGAATGGTACGAGGTACTTAAGATAGCCGCTGACATATTAATTAAAGAAGAGATACTGAGTGAAAA
TGATCAGTTGTCAAATCAGGTGGTTGTATGTTTGCTGCCATTTATGGTTATCAATAATGATGATACGGAATCTGCTGAGATGAAAATTGC
TATATATTTATCAAAATCAGGAATCTGCTCCCTGCACCCTCTATTAAGAGGCTGGGAAGAAGCTCTTGAAAATGTAATTAAAAGCACAAA
GCCAGGAAAACTAATCGGTGTAGCAAATCAGAAGATGATTGAGTTGTTGGCTGATAATATAAATTTAGGAGATCCTTCTTCAATGTTAAA
GATGGTGGAGGATTTAATAAGCGTGGGTGAGGAGGAGTCCTTTAACCTGAAGCAGAAAGTAACGTTTCATGTGATCCTGTCTGTGCTCGT
CTCTTGTTGTTCATCTTTAAAAGAAACCCACTTTCCATTTGCGATAAGAGTCTTCAGTTTGTTGCAGAAAAAAATAAAGAAGCTTGAAAG
TGTCATTACTGCAGTGGAAATCCCCTCAGAATGGCACATTGAACTGATGTTAGACAGAGGGATCCCAGTGGAGCTGTGGGCACATTATGT
AGAAGAGCTCAACAGCACTCAGAGGGTGGCCGTGGAGGACTCGGTTTTTCTTGTATTTTCCTTGAAAAAATTTATTTATGCACTGAAAGC
TCCTAAATCTTTTCCTAAAGGTGATATATGGTGGAATCCTGAACAACTGAAAGAAGACAGCAGGGACTATCTGCACTTGCTCATTGGGCT
GTTTGAGATGATGCTCAATGGTGCCGATGCTGTTCATTTCAGAGTTCTGATGAAACTTTTCATAAAGGTGCATCTAGAAGATGTTTTTCA
GTTATTCAAGTTCTGTTCTGTTTTATGGACCTATGGTTCTAGCCTTTCAAATCCACTAAACTGCAGTGTGAAAACAGTGCTGCAGACTCA
AGCTCTTTATGTGGGCTGTGCAATGCTTTCTTCTCAGAAGACACAGTGTAAACACCAACTGGCATCCATATCTTCTCCAGTGGTGACATC
TTTACTCATTAACCTGGGAAGCCCCGTAAAAGAAGTTCGTAGGGCTGCCATTCAGTGTCTCCAGGCCCTCAGTGGAGTGGCATCCCCGTT
TTATCTGATAATAGATCATTTGATTTCTAAAGCAGAGGAGATCACTTCAGATGCTGCCTATGTTATTCAGGATTTGGCTACTTTATTTGA
GGAACTACAGAGAGAAAAGAAACTGAAATCTCATCAGAAGTTGTCTGAAACTTTGAAAAACTTACTTAGTTGTGTGTATAGTTGCCCATC
TTATATAGCAAAAGATTTGATGAAAGTACTTCAGGGAGTCAACGGTGAGCCTGTCATCAATGGTTACCGAAATAAGTCCACCTTCTCTGT
GAACCGAGGTCCAGATGGCAATCCAAAGACTGTGGGGTTCTACCTGGGAACTTGGAGAGATGGGAACGTTGTCTGTGTGCAGTCTAATCA
TCTGAAAAACATCCCTGAGAAACACAGTCAAGTGGCGCAGTACTATGAAGTATTCCTTCGACAGTCTCCATTGGAGCCCTGCCTTGTATT
TCATGAAGGTGGATACTGGCGTGAGCTCACAGTCCGCACCAATAGCCAAGGGCACACAATGGCTATCATCACTTTCCATCCCCAGAAATT
AAGTCAGGAGGAGCTCCATGTTCAGAAGGAGATTGTAAAGGAATTTTTCATCAGAGGTCCTGGAGCAGCCTGTGGCTTGACCTCACTTTA
CTTCCAGGAAAGTACCATGACCCGTTGCAGCCATCAGCAGTCTCCCTATCAGCTTCTGTTTGGGGAACCCTACATCTTTGAAGAACTTCT
GAGCTTGAAGATCCGCATCTCTCCAGATGCCTTTTTCCAGATTAACACAGCTGGTGCAGAGATGCTGTATCGGACTGTGGGGGAGCTGAC
TGGAGTGAACTCTGACACCATCCTTCTTGACATCTGCTGTGGAACTGGTGTGATTGGCCTCTCTCTGGCTCAGCATACATCTCGGGTCCT
TGGGATTGAATTGTTGGAGCAGGCAGTGGAGGATGCAAGATGGACTGCAGCCTTCAATGGCATCACCAACTCTGAATTTCATACTGGTCA
AGCAGAGAAGATTTTGCCAGGGCTGCTAAAGTCAAAGGAAGATGGACAGTCAATTGTTGCTGTGGTGAACCCAGCCCGTGCCGGACTGCA
TTACAAGGTGATTCAAGCCATTCGAAACTTCAGGGCCATCCACACGCTAGTTTTTGTTTCCTGCAAGCTCCATGGTGAATCCACTAGGAA
TGTCATTGAGCTGTGCTGTCCTCCAGACCCTGCTAAGAAGCTCTTAGGCGAGCCCTTTGTCCTGCAGCAAGCTGTACCTGTGGATTTGTT
CCCTCACACCCCACATTGTGAGCTGGTGCTCCTCTTTACTCGATAAGCAGCCTCCTAGAAGACAGCAGGCTATTTGTTAAGGCTGAAGTT
TCAGAAACTTTCAGGTTTGGCATATTGCTACATTGCAGACCCTGGGAGCATTACAGTGGAAACCAATCTTTGGTTTGTGAATAGGAAGAA
TCTATTAGGCCTCTGGTCTGAGGCAGATTTTTTTTTTGAGATAGAGTCTCACTCTTGCCCAGGCTGGAGTGTCGTGGCGTGATCTCAGCT
CACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCTTCCCCAGTAGCTAGGATTAAAGGTGCGTGCCACCATGCCCGG
CTAATTTTTGTATTTTTGGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCGCCTCG
GCCTCTCAAAGTGCTGGGATTATAGGCGTGAGCCACCACACCCCGCCGCGGCTGACTTAACCTTAGATTTCAGATTCCCTTTCAATCATG
CCCGTTTGCTTGGGTTTGACCACTCCCCACTCCTGGATCTGGACTGTTTCTTCCTGTTGCTGTCAGCCTTGGTTCTAGTTTATAGTCTTG
TCTCCTCCGTTTCTGCTTATGGTGTGGACAAATGACCTTTTTTAAGCAGCTGGTAATAATTTTACATTGACTGGAGCCTGTGCATTTGCT
CAGAGATGCTACAATTTTTAGATATTTCTAAGACTTCTGGATTCTTGAGGTAGTTAAGGATTAAAACCAGAAACAGTCGAGGTTTTTTAA
AAGCAGGGTAAGCCATGAAGTGAATACAGGGTGACTGAGTGATCATCAGATGAGATTAATTCTTTTGGGTTTTCTTGGTTTTAAGGCATC
TCGAATGCCCCTTGAAAATGTAGTTTTCCCTGGTGGTGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATAATTGCTTGAA
CCTGGGAGGTGGAGGTTGCAGTGAGCTGAAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACACCATCTCAAAAAAAAAAAA
AAAAAGAAAATGTAGTTATCCCTAGGAGCAATAGCACCAATTAACTCTCACCCGTGGAGGAAGAATTGGTTATTGGAGAGACCCTAAGGG
AAAGGAGATTTTCAGAGAGACTGAATACCTATAATTGTGCTGTGTAGTGTGGAGGCAAAAAGCTCCAAAATCTAGTATAACATAATAAAC

>35948_35948_7_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366582_TRMT2B_chrX_100292062_ENST00000338687_length(amino acids)=1386AA_BP=1028
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQL
DENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT
HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISV
KVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH
HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKE
IADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA
FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGI
CSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE
THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGD
IWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM
LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKL
KSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKH
SQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTR
CSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQA
VEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPP

--------------------------------------------------------------
>35948_35948_8_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366582_TRMT2B_chrX_100292062_ENST00000372931_length(transcript)=4246nt_BP=3199nt
GAGGGTTGGGCTCCTTGGTACCATGTGGGAAGCGCTGTGAAGAGTTGTTGCCTTCCAAGATATACCCAAATTCCCAGTTCCAGCCCGTGT
CATTAAAACTCCGCTGGCGTGAAAGATGACGTCCTTAGCCCAGCAGCTGCAACGACTCGCCCTCCCTCAAAGTGATGCCAGCCTCTTATC
TAGAGATGAAGTTGCTTCTTTGTTATTTGACCCTAAGGAAGCGGCCACAATCGACAGGGACACCGCCTTCGCCATTGGATGTACTGGCCT
GGAAGAGTTGCTTGGAATTGATCCTTCCTTTGAGCAGTTTGAAGCACCGTTGTTCAGTCAGCTAGCAAAAACCTTGGAGCGAAGTGTTCA
GACCAAAGCAGTAAACAAACAGTTGGATGAAAACATTTCATTATTCCTTATTCACTTGTCGCCTTACTTCCTGCTTAAGCCAGCACAGAA
GTGTCTGGAGTGGTTGATTCACAGGTTCCATATACATCTCTATAATCAAGATAGCCTCATTGCTTGTGTTCTGCCATACCACGAGACAAG
AATATTTGTGCGAGTCATACAGCTTCTAAAAATTAATAATTCAAAGCACAGATGGTTCTGGTTGTTGCCAGTTAAGCAATCTGGAGTGCC
GTTAGCTAAAGGAACTTTGATTACCCACTGCTACAAAGATCTTGGATTCATGGATTTCATTTGCAGTTTGGTGACAAAATCTGTGAAGGT
TTTTGCTGAGTACCCGGGCAGCTCAGCTCAGTTGAGGGTGCTCTTGGCTTTCTATGCTTCTACCATAGTGTCGGCGCTGGTAGCTGCAGA
GGACGTATCAGACAATATCATCGCCAAACTATTTCCCTATATCCAAAAGGGATTGAAATCATCTTTACCAGATTACAGAGCTGCAACATA
CATGATAATATGTCAGATTTCTGTGAAAGTGACCATGGAAAATACCTTTGTGAATTCATTGGCATCACAGATCATCAAAACATTGACCAA
GATTCCCTCTTTGATCAAGGATGGGTTAAGTTGCTTGATAGTGCTCCTGCAGAGACAGAAGCCAGAGAGCCTTGGGAAAAAGCCATTCCC
TCACTTATGTAATGTTCCTGATCTTATTACAATACTTCATGGGATTTCTGAAACTTACGATGTCAGTCCTCTTCTGCATTACATGCTTCC
CCATCTGGTCGTCTCCATCATTCATCATGTTACAGGAGAAGAAACTGAAGGAATGGATGGTCAAATCTACAAGAGACACTTAGAAGCTAT
ACTTACAAAAATATCACTGAAGAACAACTTAGACCATTTGTTGGCTAGCCTTCTATTTGAAGAGTATATTTCATATAGTTCACAGGAAGA
AATGGATTCTAATAAAGTGTCTTTGCTTAATGAACAATTTCTTCCACTCATTAGGCTTTTAGAAAGCAAATACCCCAGAACATTAGATGT
TGTATTAGAGGAACACTTAAAGGAAATTGCAGATCTGAAAAAACAAGAGCTTTTCCATCAGTTTGTTTCTCTTTCTACAAGTGGAGGAAA
GTATCAGTTTTTAGCAGATTCTGATACTTCTTTGATGCTCAGCCTGAATCATCCACTTGCTCCTGTGAGAATTCTGGCCATGAATCATTT
GAAAAAGATCATGAAAACATCAAAGGAGGGTGTTGATGAATCTTTCATAAAAGAAGCTGTTTTAGCCCGATTAGGTGATGATAATATAGA
TGTTGTTTTGTCGGCTATAAGTGCTTTTGAGATTTTCAAAGAACACTTCAGTTCAGAAGTGACGATTTCAAATCTTCTGAATCTCTTTCA
AAGAGCAGAACTTTCAAAGAATGGAGAATGGTACGAGGTACTTAAGATAGCCGCTGACATATTAATTAAAGAAGAGATACTGAGTGAAAA
TGATCAGTTGTCAAATCAGGTGGTTGTATGTTTGCTGCCATTTATGGTTATCAATAATGATGATACGGAATCTGCTGAGATGAAAATTGC
TATATATTTATCAAAATCAGGAATCTGCTCCCTGCACCCTCTATTAAGAGGCTGGGAAGAAGCTCTTGAAAATGTAATTAAAAGCACAAA
GCCAGGAAAACTAATCGGTGTAGCAAATCAGAAGATGATTGAGTTGTTGGCTGATAATATAAATTTAGGAGATCCTTCTTCAATGTTAAA
GATGGTGGAGGATTTAATAAGCGTGGGTGAGGAGGAGTCCTTTAACCTGAAGCAGAAAGTAACGTTTCATGTGATCCTGTCTGTGCTCGT
CTCTTGTTGTTCATCTTTAAAAGAAACCCACTTTCCATTTGCGATAAGAGTCTTCAGTTTGTTGCAGAAAAAAATAAAGAAGCTTGAAAG
TGTCATTACTGCAGTGGAAATCCCCTCAGAATGGCACATTGAACTGATGTTAGACAGAGGGATCCCAGTGGAGCTGTGGGCACATTATGT
AGAAGAGCTCAACAGCACTCAGAGGGTGGCCGTGGAGGACTCGGTTTTTCTTGTATTTTCCTTGAAAAAATTTATTTATGCACTGAAAGC
TCCTAAATCTTTTCCTAAAGGTGATATATGGTGGAATCCTGAACAACTGAAAGAAGACAGCAGGGACTATCTGCACTTGCTCATTGGGCT
GTTTGAGATGATGCTCAATGGTGCCGATGCTGTTCATTTCAGAGTTCTGATGAAACTTTTCATAAAGGTGCATCTAGAAGATGTTTTTCA
GTTATTCAAGTTCTGTTCTGTTTTATGGACCTATGGTTCTAGCCTTTCAAATCCACTAAACTGCAGTGTGAAAACAGTGCTGCAGACTCA
AGCTCTTTATGTGGGCTGTGCAATGCTTTCTTCTCAGAAGACACAGTGTAAACACCAACTGGCATCCATATCTTCTCCAGTGGTGACATC
TTTACTCATTAACCTGGGAAGCCCCGTAAAAGAAGTTCGTAGGGCTGCCATTCAGTGTCTCCAGGCCCTCAGTGGAGTGGCATCCCCGTT
TTATCTGATAATAGATCATTTGATTTCTAAAGCAGAGGAGATCACTTCAGATGCTGCCTATGTTATTCAGGATTTGGCTACTTTATTTGA
GGAACTACAGAGAGAAAAGAAACTGAAATCTCATCAGAAGTTGTCTGAAACTTTGAAAAACTTACTTAGTTGTGTGTATAGTTGCCCATC
TTATATAGCAAAAGATTTGATGAAAGTACTTCAGGGAGTCAACGGTGAGCCTGTCATCAATGGTTACCGAAATAAGTCCACCTTCTCTGT
GAACCGAGGTCCAGATGGCAATCCAAAGACTGTGGGGTTCTACCTGGGAACTTGGAGAGATGGGAACGTTGTCTGTGTGCAGTCTAATCA
TCTGAAAAACATCCCTGAGAAACACAGTCAAGTGGCGCAGTACTATGAAGTATTCCTTCGACAGTCTCCATTGGAGCCCTGCCTTGTATT
TCATGAAGGTGGATACTGGCGTGAGCTCACAGTCCGCACCAATAGCCAAGGGCACACAATGGCTATCATCACTTTCCATCCCCAGAAATT
AAGTCAGGAGGAGCTCCATGTTCAGAAGGAGATTGTAAAGGAATTTTTCATCAGAGGTCCTGGAGCAGCCTGTGGCTTGACCTCACTTTA
CTTCCAGGAAAGTACCATGACCCGTTGCAGCCATCAGCAGTCTCCCTATCAGCTTCTGTTTGGGGAACCCTACATCTTTGAAGAACTTCT
GAGCTTGAAGATCCGCATCTCTCCAGATGCCTTTTTCCAGATTAACACAGCTGGTGCAGAGATGCTGTATCGGACTGTGGGGGAGCTGAC
TGGAGTGAACTCTGACACCATCCTTCTTGACATCTGCTGTGGAACTGGTGTGATTGGCCTCTCTCTGGCTCAGCATACATCTCGGGTCCT
TGGGATTGAATTGTTGGAGCAGGCAGTGGAGGATGCAAGATGGACTGCAGCCTTCAATGGCATCACCAACTCTGAATTTCATACTGGTCA
AGCAGAGAAGATTTTGCCAGGGCTGCTAAAGTCAAAGGAAGATGGACAGTCAATTGTTGCTGTGGTGAACCCAGCCCGTGCCGGACTGCA
TTACAAGGTGATTCAAGCCATTCGAAACTTCAGGGCCATCCACACGCTAGTTTTTGTTTCCTGCAAGCTCCATGGTGAATCCACTAGGAA
TGTCATTGAACGGAGTCTCATCTTGCTGGAGTGCAGTGGCATGGTCTCGGCTCACTACAGCCTCCACCTCCCAGGTTCAAGCGATTCTCC

>35948_35948_8_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366582_TRMT2B_chrX_100292062_ENST00000372931_length(amino acids)=1377AA_BP=1028
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQL
DENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT
HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISV
KVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH
HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKE
IADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA
FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGI
CSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE
THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGD
IWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM
LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKL
KSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKH
SQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTR
CSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQA
VEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIERSLIL

--------------------------------------------------------------
>35948_35948_9_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366582_TRMT2B_chrX_100292062_ENST00000372935_length(transcript)=5315nt_BP=3199nt
GAGGGTTGGGCTCCTTGGTACCATGTGGGAAGCGCTGTGAAGAGTTGTTGCCTTCCAAGATATACCCAAATTCCCAGTTCCAGCCCGTGT
CATTAAAACTCCGCTGGCGTGAAAGATGACGTCCTTAGCCCAGCAGCTGCAACGACTCGCCCTCCCTCAAAGTGATGCCAGCCTCTTATC
TAGAGATGAAGTTGCTTCTTTGTTATTTGACCCTAAGGAAGCGGCCACAATCGACAGGGACACCGCCTTCGCCATTGGATGTACTGGCCT
GGAAGAGTTGCTTGGAATTGATCCTTCCTTTGAGCAGTTTGAAGCACCGTTGTTCAGTCAGCTAGCAAAAACCTTGGAGCGAAGTGTTCA
GACCAAAGCAGTAAACAAACAGTTGGATGAAAACATTTCATTATTCCTTATTCACTTGTCGCCTTACTTCCTGCTTAAGCCAGCACAGAA
GTGTCTGGAGTGGTTGATTCACAGGTTCCATATACATCTCTATAATCAAGATAGCCTCATTGCTTGTGTTCTGCCATACCACGAGACAAG
AATATTTGTGCGAGTCATACAGCTTCTAAAAATTAATAATTCAAAGCACAGATGGTTCTGGTTGTTGCCAGTTAAGCAATCTGGAGTGCC
GTTAGCTAAAGGAACTTTGATTACCCACTGCTACAAAGATCTTGGATTCATGGATTTCATTTGCAGTTTGGTGACAAAATCTGTGAAGGT
TTTTGCTGAGTACCCGGGCAGCTCAGCTCAGTTGAGGGTGCTCTTGGCTTTCTATGCTTCTACCATAGTGTCGGCGCTGGTAGCTGCAGA
GGACGTATCAGACAATATCATCGCCAAACTATTTCCCTATATCCAAAAGGGATTGAAATCATCTTTACCAGATTACAGAGCTGCAACATA
CATGATAATATGTCAGATTTCTGTGAAAGTGACCATGGAAAATACCTTTGTGAATTCATTGGCATCACAGATCATCAAAACATTGACCAA
GATTCCCTCTTTGATCAAGGATGGGTTAAGTTGCTTGATAGTGCTCCTGCAGAGACAGAAGCCAGAGAGCCTTGGGAAAAAGCCATTCCC
TCACTTATGTAATGTTCCTGATCTTATTACAATACTTCATGGGATTTCTGAAACTTACGATGTCAGTCCTCTTCTGCATTACATGCTTCC
CCATCTGGTCGTCTCCATCATTCATCATGTTACAGGAGAAGAAACTGAAGGAATGGATGGTCAAATCTACAAGAGACACTTAGAAGCTAT
ACTTACAAAAATATCACTGAAGAACAACTTAGACCATTTGTTGGCTAGCCTTCTATTTGAAGAGTATATTTCATATAGTTCACAGGAAGA
AATGGATTCTAATAAAGTGTCTTTGCTTAATGAACAATTTCTTCCACTCATTAGGCTTTTAGAAAGCAAATACCCCAGAACATTAGATGT
TGTATTAGAGGAACACTTAAAGGAAATTGCAGATCTGAAAAAACAAGAGCTTTTCCATCAGTTTGTTTCTCTTTCTACAAGTGGAGGAAA
GTATCAGTTTTTAGCAGATTCTGATACTTCTTTGATGCTCAGCCTGAATCATCCACTTGCTCCTGTGAGAATTCTGGCCATGAATCATTT
GAAAAAGATCATGAAAACATCAAAGGAGGGTGTTGATGAATCTTTCATAAAAGAAGCTGTTTTAGCCCGATTAGGTGATGATAATATAGA
TGTTGTTTTGTCGGCTATAAGTGCTTTTGAGATTTTCAAAGAACACTTCAGTTCAGAAGTGACGATTTCAAATCTTCTGAATCTCTTTCA
AAGAGCAGAACTTTCAAAGAATGGAGAATGGTACGAGGTACTTAAGATAGCCGCTGACATATTAATTAAAGAAGAGATACTGAGTGAAAA
TGATCAGTTGTCAAATCAGGTGGTTGTATGTTTGCTGCCATTTATGGTTATCAATAATGATGATACGGAATCTGCTGAGATGAAAATTGC
TATATATTTATCAAAATCAGGAATCTGCTCCCTGCACCCTCTATTAAGAGGCTGGGAAGAAGCTCTTGAAAATGTAATTAAAAGCACAAA
GCCAGGAAAACTAATCGGTGTAGCAAATCAGAAGATGATTGAGTTGTTGGCTGATAATATAAATTTAGGAGATCCTTCTTCAATGTTAAA
GATGGTGGAGGATTTAATAAGCGTGGGTGAGGAGGAGTCCTTTAACCTGAAGCAGAAAGTAACGTTTCATGTGATCCTGTCTGTGCTCGT
CTCTTGTTGTTCATCTTTAAAAGAAACCCACTTTCCATTTGCGATAAGAGTCTTCAGTTTGTTGCAGAAAAAAATAAAGAAGCTTGAAAG
TGTCATTACTGCAGTGGAAATCCCCTCAGAATGGCACATTGAACTGATGTTAGACAGAGGGATCCCAGTGGAGCTGTGGGCACATTATGT
AGAAGAGCTCAACAGCACTCAGAGGGTGGCCGTGGAGGACTCGGTTTTTCTTGTATTTTCCTTGAAAAAATTTATTTATGCACTGAAAGC
TCCTAAATCTTTTCCTAAAGGTGATATATGGTGGAATCCTGAACAACTGAAAGAAGACAGCAGGGACTATCTGCACTTGCTCATTGGGCT
GTTTGAGATGATGCTCAATGGTGCCGATGCTGTTCATTTCAGAGTTCTGATGAAACTTTTCATAAAGGTGCATCTAGAAGATGTTTTTCA
GTTATTCAAGTTCTGTTCTGTTTTATGGACCTATGGTTCTAGCCTTTCAAATCCACTAAACTGCAGTGTGAAAACAGTGCTGCAGACTCA
AGCTCTTTATGTGGGCTGTGCAATGCTTTCTTCTCAGAAGACACAGTGTAAACACCAACTGGCATCCATATCTTCTCCAGTGGTGACATC
TTTACTCATTAACCTGGGAAGCCCCGTAAAAGAAGTTCGTAGGGCTGCCATTCAGTGTCTCCAGGCCCTCAGTGGAGTGGCATCCCCGTT
TTATCTGATAATAGATCATTTGATTTCTAAAGCAGAGGAGATCACTTCAGATGCTGCCTATGTTATTCAGGATTTGGCTACTTTATTTGA
GGAACTACAGAGAGAAAAGAAACTGAAATCTCATCAGAAGTTGTCTGAAACTTTGAAAAACTTACTTAGTTGTGTGTATAGTTGCCCATC
TTATATAGCAAAAGATTTGATGAAAGTACTTCAGGGAGTCAACGGTGAGCCTGTCATCAATGGTTACCGAAATAAGTCCACCTTCTCTGT
GAACCGAGGTCCAGATGGCAATCCAAAGACTGTGGGGTTCTACCTGGGAACTTGGAGAGATGGGAACGTTGTCTGTGTGCAGTCTAATCA
TCTGAAAAACATCCCTGAGAAACACAGTCAAGTGGCGCAGTACTATGAAGTATTCCTTCGACAGTCTCCATTGGAGCCCTGCCTTGTATT
TCATGAAGGTGGATACTGGCGTGAGCTCACAGTCCGCACCAATAGCCAAGGGCACACAATGGCTATCATCACTTTCCATCCCCAGAAATT
AAGTCAGGAGGAGCTCCATGTTCAGAAGGAGATTGTAAAGGAATTTTTCATCAGAGGTCCTGGAGCAGCCTGTGGCTTGACCTCACTTTA
CTTCCAGGAAAGTACCATGACCCGTTGCAGCCATCAGCAGTCTCCCTATCAGCTTCTGTTTGGGGAACCCTACATCTTTGAAGAACTTCT
GAGCTTGAAGATCCGCATCTCTCCAGATGCCTTTTTCCAGATTAACACAGCTGGTGCAGAGATGCTGTATCGGACTGTGGGGGAGCTGAC
TGGAGTGAACTCTGACACCATCCTTCTTGACATCTGCTGTGGAACTGGTGTGATTGGCCTCTCTCTGGCTCAGCATACATCTCGGGTCCT
TGGGATTGAATTGTTGGAGCAGGCAGTGGAGGATGCAAGATGGACTGCAGCCTTCAATGGCATCACCAACTCTGAATTTCATACTGGTCA
AGCAGAGAAGATTTTGCCAGGGCTGCTAAAGTCAAAGGAAGATGGACAGTCAATTGTTGCTGTGGTGAACCCAGCCCGTGCCGGACTGCA
TTACAAGGTGATTCAAGCCATTCGAAACTTCAGGGCCATCCACACGCTAGTTTTTGTTTCCTGCAAGCTCCATGGTGAATCCACTAGGAA
TGTCATTGAGCTGTGCTGTCCTCCAGACCCTGCTAAGAAGCTCTTAGGCGAGCCCTTTGTCCTGCAGCAAGCTGTACCTGTGGATTTGTT
CCCTCACACCCCACATTGTGAGCTGGTGCTCCTCTTTACTCGATAAGCAGCCTCCTAGAAGACAGCAGGCTATTTGTTAAGGCTGAAGTT
TCAGAAACTTTCAGGTTTGGCATATTGCTACATTGCAGACCCTGGGAGCATTACAGTGGAAACCAATCTTTGGTTTGTGAATAGGAAGAA
TCTATTAGGCCTCTGGTCTGAGGCAGATTTTTTTTTTGAGATAGAGTCTCACTCTTGCCCAGGCTGGAGTGTCGTGGCGTGATCTCAGCT
CACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCTTCCCCAGTAGCTAGGATTAAAGGTGCGTGCCACCATGCCCGG
CTAATTTTTGTATTTTTGGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCGCCTCG
GCCTCTCAAAGTGCTGGGATTATAGGCGTGAGCCACCACACCCCGCCGCGGCTGACTTAACCTTAGATTTCAGATTCCCTTTCAATCATG
CCCGTTTGCTTGGGTTTGACCACTCCCCACTCCTGGATCTGGACTGTTTCTTCCTGTTGCTGTCAGCCTTGGTTCTAGTTTATAGTCTTG
TCTCCTCCGTTTCTGCTTATGGTGTGGACAAATGACCTTTTTTAAGCAGCTGGTAATAATTTTACATTGACTGGAGCCTGTGCATTTGCT
CAGAGATGCTACAATTTTTAGATATTTCTAAGACTTCTGGATTCTTGAGGTAGTTAAGGATTAAAACCAGAAACAGTCGAGGTTTTTTAA
AAGCAGGGTAAGCCATGAAGTGAATACAGGGTGACTGAGTGATCATCAGATGAGATTAATTCTTTTGGGTTTTCTTGGTTTTAAGGCATC
TCGAATGCCCCTTGAAAATGTAGTTTTCCCTGGTGGTGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATAATTGCTTGAA
CCTGGGAGGTGGAGGTTGCAGTGAGCTGAAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACACCATCTCAAAAAAAAAAAA

>35948_35948_9_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366582_TRMT2B_chrX_100292062_ENST00000372935_length(amino acids)=1386AA_BP=1028
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQL
DENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT
HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISV
KVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH
HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKE
IADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA
FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGI
CSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE
THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGD
IWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM
LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKL
KSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKH
SQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTR
CSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQA
VEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPP

--------------------------------------------------------------
>35948_35948_10_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366582_TRMT2B_chrX_100292062_ENST00000372936_length(transcript)=5315nt_BP=3199nt
GAGGGTTGGGCTCCTTGGTACCATGTGGGAAGCGCTGTGAAGAGTTGTTGCCTTCCAAGATATACCCAAATTCCCAGTTCCAGCCCGTGT
CATTAAAACTCCGCTGGCGTGAAAGATGACGTCCTTAGCCCAGCAGCTGCAACGACTCGCCCTCCCTCAAAGTGATGCCAGCCTCTTATC
TAGAGATGAAGTTGCTTCTTTGTTATTTGACCCTAAGGAAGCGGCCACAATCGACAGGGACACCGCCTTCGCCATTGGATGTACTGGCCT
GGAAGAGTTGCTTGGAATTGATCCTTCCTTTGAGCAGTTTGAAGCACCGTTGTTCAGTCAGCTAGCAAAAACCTTGGAGCGAAGTGTTCA
GACCAAAGCAGTAAACAAACAGTTGGATGAAAACATTTCATTATTCCTTATTCACTTGTCGCCTTACTTCCTGCTTAAGCCAGCACAGAA
GTGTCTGGAGTGGTTGATTCACAGGTTCCATATACATCTCTATAATCAAGATAGCCTCATTGCTTGTGTTCTGCCATACCACGAGACAAG
AATATTTGTGCGAGTCATACAGCTTCTAAAAATTAATAATTCAAAGCACAGATGGTTCTGGTTGTTGCCAGTTAAGCAATCTGGAGTGCC
GTTAGCTAAAGGAACTTTGATTACCCACTGCTACAAAGATCTTGGATTCATGGATTTCATTTGCAGTTTGGTGACAAAATCTGTGAAGGT
TTTTGCTGAGTACCCGGGCAGCTCAGCTCAGTTGAGGGTGCTCTTGGCTTTCTATGCTTCTACCATAGTGTCGGCGCTGGTAGCTGCAGA
GGACGTATCAGACAATATCATCGCCAAACTATTTCCCTATATCCAAAAGGGATTGAAATCATCTTTACCAGATTACAGAGCTGCAACATA
CATGATAATATGTCAGATTTCTGTGAAAGTGACCATGGAAAATACCTTTGTGAATTCATTGGCATCACAGATCATCAAAACATTGACCAA
GATTCCCTCTTTGATCAAGGATGGGTTAAGTTGCTTGATAGTGCTCCTGCAGAGACAGAAGCCAGAGAGCCTTGGGAAAAAGCCATTCCC
TCACTTATGTAATGTTCCTGATCTTATTACAATACTTCATGGGATTTCTGAAACTTACGATGTCAGTCCTCTTCTGCATTACATGCTTCC
CCATCTGGTCGTCTCCATCATTCATCATGTTACAGGAGAAGAAACTGAAGGAATGGATGGTCAAATCTACAAGAGACACTTAGAAGCTAT
ACTTACAAAAATATCACTGAAGAACAACTTAGACCATTTGTTGGCTAGCCTTCTATTTGAAGAGTATATTTCATATAGTTCACAGGAAGA
AATGGATTCTAATAAAGTGTCTTTGCTTAATGAACAATTTCTTCCACTCATTAGGCTTTTAGAAAGCAAATACCCCAGAACATTAGATGT
TGTATTAGAGGAACACTTAAAGGAAATTGCAGATCTGAAAAAACAAGAGCTTTTCCATCAGTTTGTTTCTCTTTCTACAAGTGGAGGAAA
GTATCAGTTTTTAGCAGATTCTGATACTTCTTTGATGCTCAGCCTGAATCATCCACTTGCTCCTGTGAGAATTCTGGCCATGAATCATTT
GAAAAAGATCATGAAAACATCAAAGGAGGGTGTTGATGAATCTTTCATAAAAGAAGCTGTTTTAGCCCGATTAGGTGATGATAATATAGA
TGTTGTTTTGTCGGCTATAAGTGCTTTTGAGATTTTCAAAGAACACTTCAGTTCAGAAGTGACGATTTCAAATCTTCTGAATCTCTTTCA
AAGAGCAGAACTTTCAAAGAATGGAGAATGGTACGAGGTACTTAAGATAGCCGCTGACATATTAATTAAAGAAGAGATACTGAGTGAAAA
TGATCAGTTGTCAAATCAGGTGGTTGTATGTTTGCTGCCATTTATGGTTATCAATAATGATGATACGGAATCTGCTGAGATGAAAATTGC
TATATATTTATCAAAATCAGGAATCTGCTCCCTGCACCCTCTATTAAGAGGCTGGGAAGAAGCTCTTGAAAATGTAATTAAAAGCACAAA
GCCAGGAAAACTAATCGGTGTAGCAAATCAGAAGATGATTGAGTTGTTGGCTGATAATATAAATTTAGGAGATCCTTCTTCAATGTTAAA
GATGGTGGAGGATTTAATAAGCGTGGGTGAGGAGGAGTCCTTTAACCTGAAGCAGAAAGTAACGTTTCATGTGATCCTGTCTGTGCTCGT
CTCTTGTTGTTCATCTTTAAAAGAAACCCACTTTCCATTTGCGATAAGAGTCTTCAGTTTGTTGCAGAAAAAAATAAAGAAGCTTGAAAG
TGTCATTACTGCAGTGGAAATCCCCTCAGAATGGCACATTGAACTGATGTTAGACAGAGGGATCCCAGTGGAGCTGTGGGCACATTATGT
AGAAGAGCTCAACAGCACTCAGAGGGTGGCCGTGGAGGACTCGGTTTTTCTTGTATTTTCCTTGAAAAAATTTATTTATGCACTGAAAGC
TCCTAAATCTTTTCCTAAAGGTGATATATGGTGGAATCCTGAACAACTGAAAGAAGACAGCAGGGACTATCTGCACTTGCTCATTGGGCT
GTTTGAGATGATGCTCAATGGTGCCGATGCTGTTCATTTCAGAGTTCTGATGAAACTTTTCATAAAGGTGCATCTAGAAGATGTTTTTCA
GTTATTCAAGTTCTGTTCTGTTTTATGGACCTATGGTTCTAGCCTTTCAAATCCACTAAACTGCAGTGTGAAAACAGTGCTGCAGACTCA
AGCTCTTTATGTGGGCTGTGCAATGCTTTCTTCTCAGAAGACACAGTGTAAACACCAACTGGCATCCATATCTTCTCCAGTGGTGACATC
TTTACTCATTAACCTGGGAAGCCCCGTAAAAGAAGTTCGTAGGGCTGCCATTCAGTGTCTCCAGGCCCTCAGTGGAGTGGCATCCCCGTT
TTATCTGATAATAGATCATTTGATTTCTAAAGCAGAGGAGATCACTTCAGATGCTGCCTATGTTATTCAGGATTTGGCTACTTTATTTGA
GGAACTACAGAGAGAAAAGAAACTGAAATCTCATCAGAAGTTGTCTGAAACTTTGAAAAACTTACTTAGTTGTGTGTATAGTTGCCCATC
TTATATAGCAAAAGATTTGATGAAAGTACTTCAGGGAGTCAACGGTGAGCCTGTCATCAATGGTTACCGAAATAAGTCCACCTTCTCTGT
GAACCGAGGTCCAGATGGCAATCCAAAGACTGTGGGGTTCTACCTGGGAACTTGGAGAGATGGGAACGTTGTCTGTGTGCAGTCTAATCA
TCTGAAAAACATCCCTGAGAAACACAGTCAAGTGGCGCAGTACTATGAAGTATTCCTTCGACAGTCTCCATTGGAGCCCTGCCTTGTATT
TCATGAAGGTGGATACTGGCGTGAGCTCACAGTCCGCACCAATAGCCAAGGGCACACAATGGCTATCATCACTTTCCATCCCCAGAAATT
AAGTCAGGAGGAGCTCCATGTTCAGAAGGAGATTGTAAAGGAATTTTTCATCAGAGGTCCTGGAGCAGCCTGTGGCTTGACCTCACTTTA
CTTCCAGGAAAGTACCATGACCCGTTGCAGCCATCAGCAGTCTCCCTATCAGCTTCTGTTTGGGGAACCCTACATCTTTGAAGAACTTCT
GAGCTTGAAGATCCGCATCTCTCCAGATGCCTTTTTCCAGATTAACACAGCTGGTGCAGAGATGCTGTATCGGACTGTGGGGGAGCTGAC
TGGAGTGAACTCTGACACCATCCTTCTTGACATCTGCTGTGGAACTGGTGTGATTGGCCTCTCTCTGGCTCAGCATACATCTCGGGTCCT
TGGGATTGAATTGTTGGAGCAGGCAGTGGAGGATGCAAGATGGACTGCAGCCTTCAATGGCATCACCAACTCTGAATTTCATACTGGTCA
AGCAGAGAAGATTTTGCCAGGGCTGCTAAAGTCAAAGGAAGATGGACAGTCAATTGTTGCTGTGGTGAACCCAGCCCGTGCCGGACTGCA
TTACAAGGTGATTCAAGCCATTCGAAACTTCAGGGCCATCCACACGCTAGTTTTTGTTTCCTGCAAGCTCCATGGTGAATCCACTAGGAA
TGTCATTGAGCTGTGCTGTCCTCCAGACCCTGCTAAGAAGCTCTTAGGCGAGCCCTTTGTCCTGCAGCAAGCTGTACCTGTGGATTTGTT
CCCTCACACCCCACATTGTGAGCTGGTGCTCCTCTTTACTCGATAAGCAGCCTCCTAGAAGACAGCAGGCTATTTGTTAAGGCTGAAGTT
TCAGAAACTTTCAGGTTTGGCATATTGCTACATTGCAGACCCTGGGAGCATTACAGTGGAAACCAATCTTTGGTTTGTGAATAGGAAGAA
TCTATTAGGCCTCTGGTCTGAGGCAGATTTTTTTTTTGAGATAGAGTCTCACTCTTGCCCAGGCTGGAGTGTCGTGGCGTGATCTCAGCT
CACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCTTCCCCAGTAGCTAGGATTAAAGGTGCGTGCCACCATGCCCGG
CTAATTTTTGTATTTTTGGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCGCCTCG
GCCTCTCAAAGTGCTGGGATTATAGGCGTGAGCCACCACACCCCGCCGCGGCTGACTTAACCTTAGATTTCAGATTCCCTTTCAATCATG
CCCGTTTGCTTGGGTTTGACCACTCCCCACTCCTGGATCTGGACTGTTTCTTCCTGTTGCTGTCAGCCTTGGTTCTAGTTTATAGTCTTG
TCTCCTCCGTTTCTGCTTATGGTGTGGACAAATGACCTTTTTTAAGCAGCTGGTAATAATTTTACATTGACTGGAGCCTGTGCATTTGCT
CAGAGATGCTACAATTTTTAGATATTTCTAAGACTTCTGGATTCTTGAGGTAGTTAAGGATTAAAACCAGAAACAGTCGAGGTTTTTTAA
AAGCAGGGTAAGCCATGAAGTGAATACAGGGTGACTGAGTGATCATCAGATGAGATTAATTCTTTTGGGTTTTCTTGGTTTTAAGGCATC
TCGAATGCCCCTTGAAAATGTAGTTTTCCCTGGTGGTGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATAATTGCTTGAA
CCTGGGAGGTGGAGGTTGCAGTGAGCTGAAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACACCATCTCAAAAAAAAAAAA

>35948_35948_10_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366582_TRMT2B_chrX_100292062_ENST00000372936_length(amino acids)=1386AA_BP=1028
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQL
DENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT
HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISV
KVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH
HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKE
IADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA
FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGI
CSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE
THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGD
IWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM
LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKL
KSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKH
SQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTR
CSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQA
VEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPP

--------------------------------------------------------------
>35948_35948_11_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366582_TRMT2B_chrX_100292062_ENST00000372939_length(transcript)=5507nt_BP=3199nt
GAGGGTTGGGCTCCTTGGTACCATGTGGGAAGCGCTGTGAAGAGTTGTTGCCTTCCAAGATATACCCAAATTCCCAGTTCCAGCCCGTGT
CATTAAAACTCCGCTGGCGTGAAAGATGACGTCCTTAGCCCAGCAGCTGCAACGACTCGCCCTCCCTCAAAGTGATGCCAGCCTCTTATC
TAGAGATGAAGTTGCTTCTTTGTTATTTGACCCTAAGGAAGCGGCCACAATCGACAGGGACACCGCCTTCGCCATTGGATGTACTGGCCT
GGAAGAGTTGCTTGGAATTGATCCTTCCTTTGAGCAGTTTGAAGCACCGTTGTTCAGTCAGCTAGCAAAAACCTTGGAGCGAAGTGTTCA
GACCAAAGCAGTAAACAAACAGTTGGATGAAAACATTTCATTATTCCTTATTCACTTGTCGCCTTACTTCCTGCTTAAGCCAGCACAGAA
GTGTCTGGAGTGGTTGATTCACAGGTTCCATATACATCTCTATAATCAAGATAGCCTCATTGCTTGTGTTCTGCCATACCACGAGACAAG
AATATTTGTGCGAGTCATACAGCTTCTAAAAATTAATAATTCAAAGCACAGATGGTTCTGGTTGTTGCCAGTTAAGCAATCTGGAGTGCC
GTTAGCTAAAGGAACTTTGATTACCCACTGCTACAAAGATCTTGGATTCATGGATTTCATTTGCAGTTTGGTGACAAAATCTGTGAAGGT
TTTTGCTGAGTACCCGGGCAGCTCAGCTCAGTTGAGGGTGCTCTTGGCTTTCTATGCTTCTACCATAGTGTCGGCGCTGGTAGCTGCAGA
GGACGTATCAGACAATATCATCGCCAAACTATTTCCCTATATCCAAAAGGGATTGAAATCATCTTTACCAGATTACAGAGCTGCAACATA
CATGATAATATGTCAGATTTCTGTGAAAGTGACCATGGAAAATACCTTTGTGAATTCATTGGCATCACAGATCATCAAAACATTGACCAA
GATTCCCTCTTTGATCAAGGATGGGTTAAGTTGCTTGATAGTGCTCCTGCAGAGACAGAAGCCAGAGAGCCTTGGGAAAAAGCCATTCCC
TCACTTATGTAATGTTCCTGATCTTATTACAATACTTCATGGGATTTCTGAAACTTACGATGTCAGTCCTCTTCTGCATTACATGCTTCC
CCATCTGGTCGTCTCCATCATTCATCATGTTACAGGAGAAGAAACTGAAGGAATGGATGGTCAAATCTACAAGAGACACTTAGAAGCTAT
ACTTACAAAAATATCACTGAAGAACAACTTAGACCATTTGTTGGCTAGCCTTCTATTTGAAGAGTATATTTCATATAGTTCACAGGAAGA
AATGGATTCTAATAAAGTGTCTTTGCTTAATGAACAATTTCTTCCACTCATTAGGCTTTTAGAAAGCAAATACCCCAGAACATTAGATGT
TGTATTAGAGGAACACTTAAAGGAAATTGCAGATCTGAAAAAACAAGAGCTTTTCCATCAGTTTGTTTCTCTTTCTACAAGTGGAGGAAA
GTATCAGTTTTTAGCAGATTCTGATACTTCTTTGATGCTCAGCCTGAATCATCCACTTGCTCCTGTGAGAATTCTGGCCATGAATCATTT
GAAAAAGATCATGAAAACATCAAAGGAGGGTGTTGATGAATCTTTCATAAAAGAAGCTGTTTTAGCCCGATTAGGTGATGATAATATAGA
TGTTGTTTTGTCGGCTATAAGTGCTTTTGAGATTTTCAAAGAACACTTCAGTTCAGAAGTGACGATTTCAAATCTTCTGAATCTCTTTCA
AAGAGCAGAACTTTCAAAGAATGGAGAATGGTACGAGGTACTTAAGATAGCCGCTGACATATTAATTAAAGAAGAGATACTGAGTGAAAA
TGATCAGTTGTCAAATCAGGTGGTTGTATGTTTGCTGCCATTTATGGTTATCAATAATGATGATACGGAATCTGCTGAGATGAAAATTGC
TATATATTTATCAAAATCAGGAATCTGCTCCCTGCACCCTCTATTAAGAGGCTGGGAAGAAGCTCTTGAAAATGTAATTAAAAGCACAAA
GCCAGGAAAACTAATCGGTGTAGCAAATCAGAAGATGATTGAGTTGTTGGCTGATAATATAAATTTAGGAGATCCTTCTTCAATGTTAAA
GATGGTGGAGGATTTAATAAGCGTGGGTGAGGAGGAGTCCTTTAACCTGAAGCAGAAAGTAACGTTTCATGTGATCCTGTCTGTGCTCGT
CTCTTGTTGTTCATCTTTAAAAGAAACCCACTTTCCATTTGCGATAAGAGTCTTCAGTTTGTTGCAGAAAAAAATAAAGAAGCTTGAAAG
TGTCATTACTGCAGTGGAAATCCCCTCAGAATGGCACATTGAACTGATGTTAGACAGAGGGATCCCAGTGGAGCTGTGGGCACATTATGT
AGAAGAGCTCAACAGCACTCAGAGGGTGGCCGTGGAGGACTCGGTTTTTCTTGTATTTTCCTTGAAAAAATTTATTTATGCACTGAAAGC
TCCTAAATCTTTTCCTAAAGGTGATATATGGTGGAATCCTGAACAACTGAAAGAAGACAGCAGGGACTATCTGCACTTGCTCATTGGGCT
GTTTGAGATGATGCTCAATGGTGCCGATGCTGTTCATTTCAGAGTTCTGATGAAACTTTTCATAAAGGTGCATCTAGAAGATGTTTTTCA
GTTATTCAAGTTCTGTTCTGTTTTATGGACCTATGGTTCTAGCCTTTCAAATCCACTAAACTGCAGTGTGAAAACAGTGCTGCAGACTCA
AGCTCTTTATGTGGGCTGTGCAATGCTTTCTTCTCAGAAGACACAGTGTAAACACCAACTGGCATCCATATCTTCTCCAGTGGTGACATC
TTTACTCATTAACCTGGGAAGCCCCGTAAAAGAAGTTCGTAGGGCTGCCATTCAGTGTCTCCAGGCCCTCAGTGGAGTGGCATCCCCGTT
TTATCTGATAATAGATCATTTGATTTCTAAAGCAGAGGAGATCACTTCAGATGCTGCCTATGTTATTCAGGATTTGGCTACTTTATTTGA
GGAACTACAGAGAGAAAAGAAACTGAAATCTCATCAGAAGTTGTCTGAAACTTTGAAAAACTTACTTAGTTGTGTGTATAGTTGCCCATC
TTATATAGCAAAAGATTTGATGAAAGTACTTCAGGGAGTCAACGGTGAGCCTGTCATCAATGGTTACCGAAATAAGTCCACCTTCTCTGT
GAACCGAGGTCCAGATGGCAATCCAAAGACTGTGGGGTTCTACCTGGGAACTTGGAGAGATGGGAACGTTGTCTGTGTGCAGTCTAATCA
TCTGAAAAACATCCCTGAGAAACACAGTCAAGTGGCGCAGTACTATGAAGTATTCCTTCGACAGTCTCCATTGGAGCCCTGCCTTGTATT
TCATGAAGGTGGATACTGGCGTGAGCTCACAGTCCGCACCAATAGCCAAGGGCACACAATGGCTATCATCACTTTCCATCCCCAGAAATT
AAGTCAGGAGGAGCTCCATGTTCAGAAGGAGATTGTAAAGGAATTTTTCATCAGAGGTCCTGGAGCAGCCTGTGGCTTGACCTCACTTTA
CTTCCAGGAAAGTACCATGACCCGTTGCAGCCATCAGCAGTCTCCCTATCAGCTTCTGTTTGGGGAACCCTACATCTTTGAAGAACTTCT
GAGCTTGAAGATCCGCATCTCTCCAGATGCCTTTTTCCAGATTAACACAGCTGGTGCAGAGATGCTGTATCGGACTGTGGGGGAGCTGAC
TGGAGTGAACTCTGACACCATCCTTCTTGACATCTGCTGTGGAACTGGTGTGATTGGCCTCTCTCTGGCTCAGCATACATCTCGGGTCCT
TGGGATTGAATTGTTGGAGCAGGCAGTGGAGGATGCAAGATGGACTGCAGCCTTCAATGGCATCACCAACTCTGAATTTCATACTGGTCA
AGCAGAGAAGATTTTGCCAGGGCTGCTAAAGTCAAAGGAAGATGGACAGTCAATTGTTGCTGTGGTGAACCCAGCCCGTGCCGGACTGCA
TTACAAGGTGATTCAAGCCATTCGAAACTTCAGGGCCATCCACACGCTAGTTTTTGTTTCCTGCAAGCTCCATGGTGAATCCACTAGGAA
TGTCATTGAGCTGTGCTGTCCTCCAGACCCTGCTAAGAAGCTCTTAGGCGAGCCCTTTGTCCTGCAGCAAGCTGTACCTGTGGATTTGTT
CCCTCACACCCCACATTGTGAGCTGGTGCTCCTCTTTACTCGATAAGCAGCCTCCTAGAAGACAGCAGGCTATTTGTTAAGGCTGAAGTT
TCAGAAACTTTCAGGTTTGGCATATTGCTACATTGCAGACCCTGGGAGCATTACAGTGGAAACCAATCTTTGGTTTGTGAATAGGAAGAA
TCTATTAGGCCTCTGGTCTGAGGCAGATTTTTTTTTTGAGATAGAGTCTCACTCTTGCCCAGGCTGGAGTGTCGTGGCGTGATCTCAGCT
CACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCTTCCCCAGTAGCTAGGATTAAAGGTGCGTGCCACCATGCCCGG
CTAATTTTTGTATTTTTGGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCGCCTCG
GCCTCTCAAAGTGCTGGGATTATAGGCGTGAGCCACCACACCCCGCCGCGGCTGACTTAACCTTAGATTTCAGATTCCCTTTCAATCATG
CCCGTTTGCTTGGGTTTGACCACTCCCCACTCCTGGATCTGGACTGTTTCTTCCTGTTGCTGTCAGCCTTGGTTCTAGTTTATAGTCTTG
TCTCCTCCGTTTCTGCTTATGGTGTGGACAAATGACCTTTTTTAAGCAGCTGGTAATAATTTTACATTGACTGGAGCCTGTGCATTTGCT
CAGAGATGCTACAATTTTTAGATATTTCTAAGACTTCTGGATTCTTGAGGTAGTTAAGGATTAAAACCAGAAACAGTCGAGGTTTTTTAA
AAGCAGGGTAAGCCATGAAGTGAATACAGGGTGACTGAGTGATCATCAGATGAGATTAATTCTTTTGGGTTTTCTTGGTTTTAAGGCATC
TCGAATGCCCCTTGAAAATGTAGTTTTCCCTGGTGGTGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATAATTGCTTGAA
CCTGGGAGGTGGAGGTTGCAGTGAGCTGAAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACACCATCTCAAAAAAAAAAAA
AAAAAGAAAATGTAGTTATCCCTAGGAGCAATAGCACCAATTAACTCTCACCCGTGGAGGAAGAATTGGTTATTGGAGAGACCCTAAGGG
AAAGGAGATTTTCAGAGAGACTGAATACCTATAATTGTGCTGTGTAGTGTGGAGGCAAAAAGCTCCAAAATCTAGTATAACATAATAAAC

>35948_35948_11_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366582_TRMT2B_chrX_100292062_ENST00000372939_length(amino acids)=1386AA_BP=1028
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQL
DENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT
HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISV
KVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH
HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKE
IADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA
FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGI
CSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE
THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGD
IWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM
LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKL
KSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKH
SQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTR
CSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQA
VEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPP

--------------------------------------------------------------
>35948_35948_12_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366582_TRMT2B_chrX_100292062_ENST00000545398_length(transcript)=5511nt_BP=3199nt
GAGGGTTGGGCTCCTTGGTACCATGTGGGAAGCGCTGTGAAGAGTTGTTGCCTTCCAAGATATACCCAAATTCCCAGTTCCAGCCCGTGT
CATTAAAACTCCGCTGGCGTGAAAGATGACGTCCTTAGCCCAGCAGCTGCAACGACTCGCCCTCCCTCAAAGTGATGCCAGCCTCTTATC
TAGAGATGAAGTTGCTTCTTTGTTATTTGACCCTAAGGAAGCGGCCACAATCGACAGGGACACCGCCTTCGCCATTGGATGTACTGGCCT
GGAAGAGTTGCTTGGAATTGATCCTTCCTTTGAGCAGTTTGAAGCACCGTTGTTCAGTCAGCTAGCAAAAACCTTGGAGCGAAGTGTTCA
GACCAAAGCAGTAAACAAACAGTTGGATGAAAACATTTCATTATTCCTTATTCACTTGTCGCCTTACTTCCTGCTTAAGCCAGCACAGAA
GTGTCTGGAGTGGTTGATTCACAGGTTCCATATACATCTCTATAATCAAGATAGCCTCATTGCTTGTGTTCTGCCATACCACGAGACAAG
AATATTTGTGCGAGTCATACAGCTTCTAAAAATTAATAATTCAAAGCACAGATGGTTCTGGTTGTTGCCAGTTAAGCAATCTGGAGTGCC
GTTAGCTAAAGGAACTTTGATTACCCACTGCTACAAAGATCTTGGATTCATGGATTTCATTTGCAGTTTGGTGACAAAATCTGTGAAGGT
TTTTGCTGAGTACCCGGGCAGCTCAGCTCAGTTGAGGGTGCTCTTGGCTTTCTATGCTTCTACCATAGTGTCGGCGCTGGTAGCTGCAGA
GGACGTATCAGACAATATCATCGCCAAACTATTTCCCTATATCCAAAAGGGATTGAAATCATCTTTACCAGATTACAGAGCTGCAACATA
CATGATAATATGTCAGATTTCTGTGAAAGTGACCATGGAAAATACCTTTGTGAATTCATTGGCATCACAGATCATCAAAACATTGACCAA
GATTCCCTCTTTGATCAAGGATGGGTTAAGTTGCTTGATAGTGCTCCTGCAGAGACAGAAGCCAGAGAGCCTTGGGAAAAAGCCATTCCC
TCACTTATGTAATGTTCCTGATCTTATTACAATACTTCATGGGATTTCTGAAACTTACGATGTCAGTCCTCTTCTGCATTACATGCTTCC
CCATCTGGTCGTCTCCATCATTCATCATGTTACAGGAGAAGAAACTGAAGGAATGGATGGTCAAATCTACAAGAGACACTTAGAAGCTAT
ACTTACAAAAATATCACTGAAGAACAACTTAGACCATTTGTTGGCTAGCCTTCTATTTGAAGAGTATATTTCATATAGTTCACAGGAAGA
AATGGATTCTAATAAAGTGTCTTTGCTTAATGAACAATTTCTTCCACTCATTAGGCTTTTAGAAAGCAAATACCCCAGAACATTAGATGT
TGTATTAGAGGAACACTTAAAGGAAATTGCAGATCTGAAAAAACAAGAGCTTTTCCATCAGTTTGTTTCTCTTTCTACAAGTGGAGGAAA
GTATCAGTTTTTAGCAGATTCTGATACTTCTTTGATGCTCAGCCTGAATCATCCACTTGCTCCTGTGAGAATTCTGGCCATGAATCATTT
GAAAAAGATCATGAAAACATCAAAGGAGGGTGTTGATGAATCTTTCATAAAAGAAGCTGTTTTAGCCCGATTAGGTGATGATAATATAGA
TGTTGTTTTGTCGGCTATAAGTGCTTTTGAGATTTTCAAAGAACACTTCAGTTCAGAAGTGACGATTTCAAATCTTCTGAATCTCTTTCA
AAGAGCAGAACTTTCAAAGAATGGAGAATGGTACGAGGTACTTAAGATAGCCGCTGACATATTAATTAAAGAAGAGATACTGAGTGAAAA
TGATCAGTTGTCAAATCAGGTGGTTGTATGTTTGCTGCCATTTATGGTTATCAATAATGATGATACGGAATCTGCTGAGATGAAAATTGC
TATATATTTATCAAAATCAGGAATCTGCTCCCTGCACCCTCTATTAAGAGGCTGGGAAGAAGCTCTTGAAAATGTAATTAAAAGCACAAA
GCCAGGAAAACTAATCGGTGTAGCAAATCAGAAGATGATTGAGTTGTTGGCTGATAATATAAATTTAGGAGATCCTTCTTCAATGTTAAA
GATGGTGGAGGATTTAATAAGCGTGGGTGAGGAGGAGTCCTTTAACCTGAAGCAGAAAGTAACGTTTCATGTGATCCTGTCTGTGCTCGT
CTCTTGTTGTTCATCTTTAAAAGAAACCCACTTTCCATTTGCGATAAGAGTCTTCAGTTTGTTGCAGAAAAAAATAAAGAAGCTTGAAAG
TGTCATTACTGCAGTGGAAATCCCCTCAGAATGGCACATTGAACTGATGTTAGACAGAGGGATCCCAGTGGAGCTGTGGGCACATTATGT
AGAAGAGCTCAACAGCACTCAGAGGGTGGCCGTGGAGGACTCGGTTTTTCTTGTATTTTCCTTGAAAAAATTTATTTATGCACTGAAAGC
TCCTAAATCTTTTCCTAAAGGTGATATATGGTGGAATCCTGAACAACTGAAAGAAGACAGCAGGGACTATCTGCACTTGCTCATTGGGCT
GTTTGAGATGATGCTCAATGGTGCCGATGCTGTTCATTTCAGAGTTCTGATGAAACTTTTCATAAAGGTGCATCTAGAAGATGTTTTTCA
GTTATTCAAGTTCTGTTCTGTTTTATGGACCTATGGTTCTAGCCTTTCAAATCCACTAAACTGCAGTGTGAAAACAGTGCTGCAGACTCA
AGCTCTTTATGTGGGCTGTGCAATGCTTTCTTCTCAGAAGACACAGTGTAAACACCAACTGGCATCCATATCTTCTCCAGTGGTGACATC
TTTACTCATTAACCTGGGAAGCCCCGTAAAAGAAGTTCGTAGGGCTGCCATTCAGTGTCTCCAGGCCCTCAGTGGAGTGGCATCCCCGTT
TTATCTGATAATAGATCATTTGATTTCTAAAGCAGAGGAGATCACTTCAGATGCTGCCTATGTTATTCAGGATTTGGCTACTTTATTTGA
GGAACTACAGAGAGAAAAGAAACTGAAATCTCATCAGAAGTTGTCTGAAACTTTGAAAAACTTACTTAGTTGTGTGTATAGTTGCCCATC
TTATATAGCAAAAGATTTGATGAAAGTACTTCAGGGAGTCAACGGTGAGCCTGTCATCAATGGTTACCGAAATAAGTCCACCTTCTCTGT
GAACCGAGGTCCAGATGGCAATCCAAAGACTGTGGGGTTCTACCTGGGAACTTGGAGAGATGGGAACGTTGTCTGTGTGCAGTCTAATCA
TCTGAAAAACATCCCTGAGAAACACAGTCAAGTGGCGCAGTACTATGAAGTATTCCTTCGACAGTCTCCATTGGAGCCCTGCCTTGTATT
TCATGAAGGTGGATACTGGCGTGAGCTCACAGTCCGCACCAATAGCCAAGGGCACACAATGGCTATCATCACTTTCCATCCCCAGAAATT
AAGTCAGGAGGAGCTCCATGTTCAGAAGGAGATTGTAAAGGAATTTTTCATCAGAGGTCCTGGAGCAGCCTGTGGCTTGACCTCACTTTA
CTTCCAGGAAAGTACCATGACCCGTTGCAGCCATCAGCAGTCTCCCTATCAGCTTCTGTTTGGGGAACCCTACATCTTTGAAGAACTTCT
GAGCTTGAAGATCCGCATCTCTCCAGATGCCTTTTTCCAGATTAACACAGCTGGTGCAGAGATGCTGTATCGGACTGTGGGGGAGCTGAC
TGGAGTGAACTCTGACACCATCCTTCTTGACATCTGCTGTGGAACTGGTGTGATTGGCCTCTCTCTGGCTCAGCATACATCTCGGGTCCT
TGGGATTGAATTGTTGGAGCAGGCAGTGGAGGATGCAAGATGGACTGCAGCCTTCAATGGCATCACCAACTCTGAATTTCATACTGGTCA
AGCAGAGAAGATTTTGCCAGGGCTGCTAAAGTCAAAGGAAGATGGACAGTCAATTGTTGCTGTGGTGAACCCAGCCCGTGCCGGACTGCA
TTACAAGGTGATTCAAGCCATTCGAAACTTCAGGGCCATCCACACGCTAGTTTTTGTTTCCTGCAAGCTCCATGGTGAATCCACTAGGAA
TGTCATTGAGCTGTGCTGTCCTCCAGACCCTGCTAAGAAGCTCTTAGGCGAGCCCTTTGTCCTGCAGCAAGCTGTACCTGTGGATTTGTT
CCCTCACACCCCACATTGTGAGCTGGTGCTCCTCTTTACTCGATAAGCAGCCTCCTAGAAGACAGCAGGCTATTTGTTAAGGCTGAAGTT
TCAGAAACTTTCAGGTTTGGCATATTGCTACATTGCAGACCCTGGGAGCATTACAGTGGAAACCAATCTTTGGTTTGTGAATAGGAAGAA
TCTATTAGGCCTCTGGTCTGAGGCAGATTTTTTTTTTGAGATAGAGTCTCACTCTTGCCCAGGCTGGAGTGTCGTGGCGTGATCTCAGCT
CACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCTTCCCCAGTAGCTAGGATTAAAGGTGCGTGCCACCATGCCCGG
CTAATTTTTGTATTTTTGGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCGCCTCG
GCCTCTCAAAGTGCTGGGATTATAGGCGTGAGCCACCACACCCCGCCGCGGCTGACTTAACCTTAGATTTCAGATTCCCTTTCAATCATG
CCCGTTTGCTTGGGTTTGACCACTCCCCACTCCTGGATCTGGACTGTTTCTTCCTGTTGCTGTCAGCCTTGGTTCTAGTTTATAGTCTTG
TCTCCTCCGTTTCTGCTTATGGTGTGGACAAATGACCTTTTTTAAGCAGCTGGTAATAATTTTACATTGACTGGAGCCTGTGCATTTGCT
CAGAGATGCTACAATTTTTAGATATTTCTAAGACTTCTGGATTCTTGAGGTAGTTAAGGATTAAAACCAGAAACAGTCGAGGTTTTTTAA
AAGCAGGGTAAGCCATGAAGTGAATACAGGGTGACTGAGTGATCATCAGATGAGATTAATTCTTTTGGGTTTTCTTGGTTTTAAGGCATC
TCGAATGCCCCTTGAAAATGTAGTTTTCCCTGGTGGTGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATAATTGCTTGAA
CCTGGGAGGTGGAGGTTGCAGTGAGCTGAAATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACACCATCTCAAAAAAAAAAAA
AAAAAGAAAATGTAGTTATCCCTAGGAGCAATAGCACCAATTAACTCTCACCCGTGGAGGAAGAATTGGTTATTGGAGAGACCCTAAGGG
AAAGGAGATTTTCAGAGAGACTGAATACCTATAATTGTGCTGTGTAGTGTGGAGGCAAAAAGCTCCAAAATCTAGTATAACATAATAAAC

>35948_35948_12_HEATR1-TRMT2B_HEATR1_chr1_236739519_ENST00000366582_TRMT2B_chrX_100292062_ENST00000545398_length(amino acids)=1386AA_BP=1028
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQL
DENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLIT
HCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISV
KVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIH
HVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKE
IADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISA
FEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGI
CSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKE
THFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGD
IWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAM
LSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKL
KSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKH
SQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTR
CSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQA
VEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPP

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for HEATR1-TRMT2B

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for HEATR1-TRMT2B

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for HEATR1-TRMT2B

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source