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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:HEATR5A-HECTD1 (FusionGDB2 ID:35963)

Fusion Gene Summary for HEATR5A-HECTD1

check button Fusion gene summary
Fusion gene informationFusion gene name: HEATR5A-HECTD1
Fusion gene ID: 35963
HgeneTgene
Gene symbol

HEATR5A

HECTD1

Gene ID

25938

25831

Gene nameHEAT repeat containing 5AHECT domain E3 ubiquitin protein ligase 1
SynonymsC14orf125EULIR
Cytomap

14q12

14q12

Type of geneprotein-codingprotein-coding
DescriptionHEAT repeat-containing protein 5AE3 ubiquitin-protein ligase HECTD1E3 ligase for inhibin receptorHECT domain containing E3 ubiquitin protein ligase 1HECT domain-containing protein 1HECT-type E3 ubiquitin transferase HECTD1
Modification date2020031320200322
UniProtAcc

Q86XA9

Q9ULT8

Ensembl transtripts involved in fusion geneENST00000389961, ENST00000439727, 
ENST00000543095, ENST00000382464, 
ENST00000404677, ENST00000439348, 
ENST00000556474, ENST00000399332, 
ENST00000553700, 
Fusion gene scores* DoF score4 X 5 X 4=808 X 9 X 5=360
# samples 59
** MAII scorelog2(5/80*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/360*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: HEATR5A [Title/Abstract] AND HECTD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointHEATR5A(31889675)-HECTD1(31598510), # samples:1
HEATR5A(31771501)-HECTD1(31602620), # samples:1
HECTD1(31642362)-HEATR5A(31828263), # samples:1
HECTD1(31675003)-HEATR5A(31795548), # samples:1
HECTD1(31675003)-HEATR5A(31782396), # samples:1
HECTD1(31604078)-HEATR5A(31814482), # samples:1
Anticipated loss of major functional domain due to fusion event.HECTD1-HEATR5A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
HEATR5A-HECTD1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across HEATR5A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across HECTD1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-DS-A3LQ-01AHEATR5Achr14

31889675

-HECTD1chr14

31598510

-
ChimerDB4LUSCTCGA-63-A5MLHEATR5Achr14

31771501

-HECTD1chr14

31602620

-


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Fusion Gene ORF analysis for HEATR5A-HECTD1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000389961ENST00000556474HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
5CDS-intronENST00000439727ENST00000556474HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
5CDS-intronENST00000543095ENST00000556474HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
5UTR-3CDSENST00000382464ENST00000399332HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
5UTR-3CDSENST00000382464ENST00000553700HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
5UTR-3CDSENST00000543095ENST00000399332HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
5UTR-3CDSENST00000543095ENST00000553700HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
5UTR-intronENST00000382464ENST00000556474HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
5UTR-intronENST00000543095ENST00000556474HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
Frame-shiftENST00000543095ENST00000399332HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
Frame-shiftENST00000543095ENST00000553700HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
In-frameENST00000389961ENST00000399332HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
In-frameENST00000389961ENST00000553700HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
In-frameENST00000439727ENST00000399332HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
In-frameENST00000439727ENST00000553700HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
intron-3CDSENST00000382464ENST00000399332HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
intron-3CDSENST00000382464ENST00000553700HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
intron-3CDSENST00000389961ENST00000399332HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
intron-3CDSENST00000389961ENST00000553700HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
intron-3CDSENST00000404677ENST00000399332HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
intron-3CDSENST00000404677ENST00000399332HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
intron-3CDSENST00000404677ENST00000553700HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
intron-3CDSENST00000404677ENST00000553700HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
intron-3CDSENST00000439348ENST00000399332HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
intron-3CDSENST00000439348ENST00000399332HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
intron-3CDSENST00000439348ENST00000553700HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
intron-3CDSENST00000439348ENST00000553700HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
intron-3CDSENST00000439727ENST00000399332HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
intron-3CDSENST00000439727ENST00000553700HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
intron-intronENST00000382464ENST00000556474HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
intron-intronENST00000389961ENST00000556474HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
intron-intronENST00000404677ENST00000556474HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
intron-intronENST00000404677ENST00000556474HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
intron-intronENST00000439348ENST00000556474HEATR5Achr14

31889675

-HECTD1chr14

31598510

-
intron-intronENST00000439348ENST00000556474HEATR5Achr14

31771501

-HECTD1chr14

31602620

-
intron-intronENST00000439727ENST00000556474HEATR5Achr14

31889675

-HECTD1chr14

31598510

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000439727HEATR5Achr1431771501-ENST00000399332HECTD1chr1431602620-95624662287492915
ENST00000439727HEATR5Achr1431771501-ENST00000553700HECTD1chr1431602620-95624662287492915
ENST00000389961HEATR5Achr1431771501-ENST00000399332HECTD1chr1431602620-103465446095333177
ENST00000389961HEATR5Achr1431771501-ENST00000553700HECTD1chr1431602620-103465446095333177

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000439727ENST00000399332HEATR5Achr1431771501-HECTD1chr1431602620-0.0003992160.9996008
ENST00000439727ENST00000553700HEATR5Achr1431771501-HECTD1chr1431602620-0.0003992160.9996008
ENST00000389961ENST00000399332HEATR5Achr1431771501-HECTD1chr1431602620-0.0003536560.9996463
ENST00000389961ENST00000553700HEATR5Achr1431771501-HECTD1chr1431602620-0.0003536560.9996463

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Fusion Genomic Features for HEATR5A-HECTD1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for HEATR5A-HECTD1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:31889675/chr14:31598510)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
HEATR5A

Q86XA9

HECTD1

Q9ULT8

FUNCTION: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure. {ECO:0000250|UniProtKB:Q69ZR2}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHEATR5Achr14:31771501chr14:31602620ENST00000389961-32351079_111618152041.0RepeatNote=HEAT 2
HgeneHEATR5Achr14:31771501chr14:31602620ENST00000389961-3235846_88318152041.0RepeatNote=HEAT 1
TgeneHECTD1chr14:31771501chr14:31602620ENST0000039933222431350_164912482611.0Compositional biasNote=Ser-rich
TgeneHECTD1chr14:31771501chr14:31602620ENST0000055370022431350_164912482611.0Compositional biasNote=Ser-rich
TgeneHECTD1chr14:31771501chr14:31602620ENST0000039933222431266_133812482611.0DomainMIB/HERC2
TgeneHECTD1chr14:31771501chr14:31602620ENST0000039933222432151_261012482611.0DomainHECT
TgeneHECTD1chr14:31771501chr14:31602620ENST0000055370022431266_133812482611.0DomainMIB/HERC2
TgeneHECTD1chr14:31771501chr14:31602620ENST0000055370022432151_261012482611.0DomainHECT
TgeneHECTD1chr14:31771501chr14:31602620ENST0000039933222432029_210312482611.0RegionNote=K-box
TgeneHECTD1chr14:31771501chr14:31602620ENST0000055370022432029_210312482611.0RegionNote=K-box

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHEATR5Achr14:31771501chr14:31602620ENST00000382464-131079_11160114.0RepeatNote=HEAT 2
HgeneHEATR5Achr14:31771501chr14:31602620ENST00000382464-13846_8830114.0RepeatNote=HEAT 1
HgeneHEATR5Achr14:31771501chr14:31602620ENST00000439348-1341079_111601966.0RepeatNote=HEAT 2
HgeneHEATR5Achr14:31771501chr14:31602620ENST00000439348-134846_88301966.0RepeatNote=HEAT 1
TgeneHECTD1chr14:31771501chr14:31602620ENST000003993322243395_42412482611.0RepeatNote=ANK 1
TgeneHECTD1chr14:31771501chr14:31602620ENST000003993322243426_45512482611.0RepeatNote=ANK 2
TgeneHECTD1chr14:31771501chr14:31602620ENST000003993322243459_49112482611.0RepeatNote=ANK 3
TgeneHECTD1chr14:31771501chr14:31602620ENST000003993322243579_61212482611.0RepeatNote=ANK 4
TgeneHECTD1chr14:31771501chr14:31602620ENST000005537002243395_42412482611.0RepeatNote=ANK 1
TgeneHECTD1chr14:31771501chr14:31602620ENST000005537002243426_45512482611.0RepeatNote=ANK 2
TgeneHECTD1chr14:31771501chr14:31602620ENST000005537002243459_49112482611.0RepeatNote=ANK 3
TgeneHECTD1chr14:31771501chr14:31602620ENST000005537002243579_61212482611.0RepeatNote=ANK 4


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Fusion Gene Sequence for HEATR5A-HECTD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>35963_35963_1_HEATR5A-HECTD1_HEATR5A_chr14_31771501_ENST00000389961_HECTD1_chr14_31602620_ENST00000399332_length(transcript)=10346nt_BP=5446nt
ATGGAATTAGCTCATAGCTTACTGCTGAATGAAGAAGCATACAATCAACTAGGTGAAGTTCAGAAGGCAGAGTTTATTTTTGAGTGGTTG
AGATACTTGGAGAAGCTCTTGTTGGCAACCAGCAGGAATGATGTAAGGGAGAAACAGAAGACTCTTGTTGAACAGCTCCTGTCTTTGTTG
AACAGCTCCCCAGGGCCTCCTACCCGCAAACTGCTTGCTAAGAATCTAGCCATACTTTATAGTATTGGAGACACATTCTCCGTTCATGAA
GCAATCGATAAATGTAATGATCTTATTCGTAGCAAAGATGATTCTCCAAGTTATCTTCCCACTAAGCTTGCTGCTGTGGTATGTTTGGGT
TCCTTGTACAAGAAGTTGGGTAGAATACTGGGTAACACCTTTACTGATACAGTGGGGAATATTCTTAAAGCTATGAAGAGTGCAGAGTCT
CAAGGCCGATATGAGATTATGCTAAGTCTGCAAAATATATTGAATGGACTAGGAGCTGCCGCTGCACCTTGTCACAGGGATGTTTATAAA
GCTGCTAGATCCTGCTTGACAGATAGATCCATGGCTGTTCGTTGTGCTGCTGCAAAGAATGAAGCCATCTTTATGTGGAGTACGGACCTG
GACAGTGTGGCCACACTGTGTTTTAAGTCCTTTGAAGGTTCCAATTATGATGTGCGGATTTCTGTTTCAAAGTTACTAGGCATAATATTA
GCTAAAGCTGTAATTTCTAAACATCCAGGAACAGCAGCCTCACGTCAAAGCATTCGCAGAGTATCTTTGGAGGAAGTTCTGGAATTACTA
GGAACAGGGTTTCTACGTGGGAGTTCAGGATTCCTTCGAGCCAGTGGAGATATGCTGAAAGGAACCAGTTCAGTCAGTAGGGATGTTCGA
GTTGGAGTTACTCAGGCTTATGTGGTATTTGTTTCAACACTAGGAGGAGCTTGGCTAGAGAAAAATTTTGCTGCCTTTTTTTCTCATATC
CTAAGCCTTGCGTCACCGTCACACCCTAAAGCCACCCAAACTCAGATCGATGCCGTCTGCTGTCGCCGTTGTGTTTCATTTATTCTTCGA
ACTACTATAGGTGGTCTTCTTGGAGAAAAGGCTCAGCTTGCTGCTGTAAAGGATATTTGCCAGGCCATCTGGAAGCTAAAGAAAGTTATG
GATGCCGTAATGAGTGATGGTAATTTGGAAACCCGGCTTGGTTCCACAGATGTAGCCGCTAGCCAACATATGCTGGTTTGTGCTTTACAA
GAACTTGGAAATCTCATACACAATCTTGGCACCACAGCGGCACCTTTGCTACAGGATTCAAGTACAGGTCTCCTTGACAGTATCTTGTCA
GTTATTCTTCATCCTAGCATTTCTGTTCGACTAGCAGCAGCTTGGTGTTTACACTGCATTGCCGTGGCATTACCCTCCTACCTAACACCA
CTCTTGGATCGTTGCCTTGAACGGCTTACTGGACATAAGTCTTCACCTGAAGCAGTGACTGGCTTCAGTTTTGCTGTAGCAGCTTTGTTG
GGAGCAGTAAAACATTGTCCTTTAGGAATTCCTCATGGAAAAGGCAAGATTATTATGACATTAGCAGAGGATTTGCTGTGTTCTGCTGCT
CAAAACAGTCGCCTTTCAGCTCAGCGCACACAAGCTGGATGGTTGCTGATTTCTGCTCTGATGACATTAGGTCCTGCAGTTGTTAGCCAT
CACCTTGCTCGAGTTCTGCTGTTGTGGAAGTGTGTCTTTCCAGCATCTCCTAAAGATCTAGAAACAGAAAAGAGCCGAGGAGATTCGTTT
ACATGGCAGGTGACCCTGGAAGGACGAGCTGGTGCACTGTGTGCTATCAAGAGCTTTGTTTCCCACTGTGGTGATCTTCTTACTGAGGAA
GTAACTCAGCGTCTTCTTCCACCACTTCCTTGTGCTGTGGATTTGCTAACTCAGCTTTCTTCAATACTAAAAATGTATGGAAGTCCTTTG
AAAACACCGTCAGTGGTTTATAGACAAAGACTTTATGAACTGTTGATTTTATTACCTCCTGAGACCTATGAAGGAAACCTCTGTGCTATC
CTCAGAGAGCTGGCTGCTGACTTGACTGCCCCTGATATTCAGGTGGCAGCATCTACATTTTTACTTCCACCCCTCTGTCATCAGGATGAT
CTTTTGATACTAAGTCCTTTCCTACAAGAGACTGACCATAGATTTATTGAAGAACAGCTCCTGCTTGGTAATGGTGTTGCTTGCGGAAGT
CTTGAATATGACCCTTATTCGATTTATGAGAAAGATGTAGAGGGAGATTCAGTGCCTAAGCCCTTACCTCCAGCACTATCAGTTATTAGT
TCTGCATCCAAGCTCTTTGGGGTTGTATGCGCTCATGTGGGAGAAACTCAAAGGCTTCTTATATTGGAACAGCTTTTGGACAGTATAAAG
CACACAAAAGGAGCTCGTCAGCAAGTGGTTCAGTTACATGTTGTTTCTTCAGTTTCTAGTTTCTTGAAGTACGTGGCTGGCTCCAAGGGA
TGTTTAGGTCCAGAAGAAATGAAAAGATTTGCCTTAACATTAGTTATGGGAGCCCTAGAAAGCCCCAACCCCTTGCTGAGATGTGCAGCT
GCAGAGTCATGGGCTAGATTAGCCCAAGTGGTAGATGATGGAGCTTTTACTGCTGGATTAGCTCAAGTTAGCTTTGACAAATTGAAATCA
GCAAGGGATGTGGTTACCAGAACAGGACACTCATTGGCCTTGGGGTCCCTACATAGGTATTTAGGAGGAATAAGTTCTTCTCAACACCTA
AATTCTTGTATTGGAATCCTTTATACTTTGGCGCAGGACAGCACTTCTCCTGATGTGCAGACCTGGGCATTACATTCTCTATCATTGATC
ATTGATTCTGCTGGCCCACTCTATTATGTGCATGTGGAACCTACCCTTTCTCTTATTATAATGTTGTTGTTAAATGTGCCTCCTACTCAT
GCTGAAGTTCACCAAAGCCTTGGTCGCTGTTTGAATGCCCTTATTACCACGTTAGGTCCAGAGCTACAAGGTAACAGTACTTCAATTTCT
ACCTTAAGGACTTCCTGTCTACTGGGTTGTGCAGTAATGCAAGATAACCCAGACTGCCTTGTTCAAGCTCAGGCCATCTCTTGCCTTCAG
CAGCTTCATATGTTTGCTCCACGACATGTCAACTTGTCTAGCCTGGTTAGCTGCCTCTGTGTGAATCTTTGTAGCCCCTACTTGTTACTG
AGAAGAGCAGTACTGGCTTGCTTACGTCAGCTTGTACAAAGAGAAGCAGCTGAAGTTTCAGAACATGCTGTTATGCTTGCTAAGGATAGC
AGAGAAGAGTTGACTCCAGATGCTAACATCAGAGAAGTTGGCCTTGAGGGGGCATTGTTGATCTTACTAGACAAGGAGACAGATGAGAGA
TTATGCCATGATATCAAAGAGACTTTAAATTATATGCTTACATCTATGGCAGTGGAAAAACTCTCCCTGTGGTTAAAGCTTTGTAAAGAT
GTACTTGCTGCATCAGCTGATTTTACAGCTGTAACTTGTGTGGATACAATGCAAGAAGAAGAAGGAGATAAAGGGGATGATGCCTCAGTC
CTGACCACCAGACGTGATGAAAAATCCCATCCTTTTACCAATCCCCGATGGGCTACTAGAGTCTTTGCTGCTGAATGTGTCTGTAGGATA
ATTAACCAATGTGAGAATGCTAACAGTGCACATTTTGACATTGCTTTAGCACAAGAAATGAAAAAAAGAGATTCAAGAAATGACTTTTTG
GTACTGCATCTTGCTGACTTAATTCGCATGGCTTTTATGGCTGCCACAGATCACAGTGACCAGCTCCGTCTTTCTGGCCTTGAAATGCTG
TTAGTTGTTATTCGGCGATTTGCAACTGTTCCAGAACCAGAGTTTCCAGGTCATGTGATTCTGGAACAGTATCAAGCCAATGTAGGAGCA
GCGCTTAGACCAGCCTTCACTTCAGAGACACCACCTGATGTCACTGCCAAAGCATGTCAGGTTTGCAGTGCCTGGATAGCAAGTGGAGTT
GTAAGTGACCTTAATGATCTCCGAAGAGTTCATCAGTTGCTTGTTTCATCGTTAACTAAAATACAGGCTGGAAAAGAAGCTCTAAGTCAC
TTATATAATGAAAGTGCTTCTACCATGGAGATCTTAGCTGTGCTTAAAGCCTGGGCAGAGGTCTACATAATTGCTGTGCAAAGACATAAA
AACCACAGACAACCTTTGAAGACTACCACCTGTTTAGAAGACGGTATCAGAAATGGATCATGTTCATCAGATGGACTGCTTGACTTAGTC
TATGCAGATCTTGGCACACTAAGCAGACTCTGGCTTGCTGCACTTCAGGATTTTGCTCTTTTAACTTTGCCTTCAGAATTTGCCTCCCAA
CTTCCTGCTGAAGGTGGTGCTTTCTACACAGCAGAGACTAGTGAAAATGCAAAATTGCATTATTACAACTCCTGGGCACTTATCCTCCAT
GCTACAGCATTGTGGCTTACAAGCACGGGTTTTGTTGTTGCTGACCCAGATGAAGGAGCATCTAATCTCTCCAGGCCTGTAACACCAACT
TCCATGTGTCAGGGTTCATCATCTGGGGCTACCATAAAGTCCCCTGAGGATGTCTACACTGATAGATTCCATCTTATTTTAGGAATCAGC
GTGGAATTTCTATGTTCCTTACGTTCAGATGCAACCATGGAAAGCATAACTGCTTGTTTACATGCATTGCAAGCACTTCTAGATGTACCT
TGGCCCAGATCAAAAATTGGCAGTGATCAGGACTTGGGTATAGAATTGCTGAATGTTCTACATCGAGTAATTTTAACCAGAGAATCACCT
TCCATTCAGTTGGCTTCACTTGAAGTGGTAAGGCAGATTATCTGTGCTGCTCAAGAACATGTGAAGGAAAAAAGACGAAGTGCAGAAGTT
GATGATGGGGCTGCTGAAAAGGAAACTCTGCCAGAGTTTGGAGAGGGAAAGGACACCGGAGGACTTGTGCCTGGAAAGTCTTTGGTCTTT
GCAACACTGGAATTGTGTGTATGCATTCTAGTTAGACAGCTCCCAGAATTAAACCCTAAATTGACAGGTAGCCCAGGAGTAAAAGCTACG
AAGCCACAGATACTATTAGAAGATGGAAGTAGATTGGTTTCAGCTGCATTGGTTATCCTTTCCGAACTTCCTGCAGTGTGCTCTCCTGAA
GGAAGCATCTCAATTCTCCCTACTATATTGTACCTCACAATCGGGGTCCTCAGAGAGACTGCTGTGAAGTTACCTGGGGGCCAGTTATCT
TCGACAGTTGCAGCTTCCCTACAGGCTCTAAAAGGAATATTATCTTCTCCCATGGCCCGGGCAGAAAAGAGCCGTACTGCTTGGACTGAC
CTTCTCCGAAGTGCCTTAACAACAATTCTTGACTGTTGGGATCCAGGGAAAGCAGCTAAAGAAGCAGAAGCTAATCTTAGACGGCAGAGA
CGTCTAGTACGTTCCCAGGTTCTGAAATACATGGTTCCAGGAGCTCGTGTTATCAGAGGCCTGGATTGGAAATGGCGAGATCAGGATGGC
AGCCCACAGGGAGAAGGCACTGTCACAGGAGAACTACACAATGGCTGGATTGATGTCACCTGGGATGCTGGTGGCTCAAACTCTTACCGT
ATGGGCGCAGAAGGAAAATTTGACCTCAAGCTTGCACCAGGGTACGACCCTGATACAGTGGCATCACCCAAACCTGTTTCATCCACTGTT
TCAGGCACAACGCAATCATGGAGCAGCTTGGTGAAAAACAACTGTCCAGACAAGACATCTGCTGCTGCAGGCTCCTCAAGTAGAAAAGGA
AGCAGCAGTTCTGTGTGTAGCGTGGCCAGTAGCAGCGACATCAGCTTGGGTTCGACCAAAACGGAACGGAGATCAGAAATTGTAATGGAA
CACAGTATAGTTTCAGGAGCTGATGTCCATGAACCAATTGTTGTTCTTTCATCTGCTGAAAACGTCCCTCAAACAGAAGTAGGGTCATCT
TCCAGTGCAAGCACCAGCACCTTAACAGCGGAAACGGGAAGTGAAAATGCTGAAAGGAAGTTAGGCCCTGATAGTTCTGTTCGTACTCCT
GGGGAGTCTAGTGCAATATCCATGGGAATTGTCAGTGTTAGTTCTCCTGATGTTAGTTCAGTATCTGAATTAACTAATAAAGAAGCAGCT
TCACAACGACCTCTTAGCTCTTCAGCAAGTAACAGACTGTCAGTGAGTTCTTTGTTGGCTGCTGGGGCCCCTATGAGCTCTAGTGCAAGT
GTACCTAACCTGTCCTCAAGAGAAACATCTAGCTTGGAGAGTTTTGTAAGGAGAGTGGCAAACATAGCACGGACTAATGCCACGAACAAC
ATGAATCTAAGCCGAAGCAGCAGTGATAACAACACTAATACTTTGGGGAGGAATGTGATGAGCACAGCAACTTCTCCTCTTATGGGTGCT
CAGAGTTTCCCTAATTTGACCACACCTGGTACTACATCAACAGTGACTATGTCAACATCCAGTGTTACTAGCAGCAGCAATGTAGCTACA
GCAACAACAGTTTTATCAGTTGGTCAATCTTTAAGTAACACTTTAACCACCAGCCTCACATCAACTTCCAGTGAGAGTGACACAGGTCAG
GAAGCAGAATATTCCTTATATGATTTCCTTGATAGCTGCCGTGCCAGTACTCTATTGGCTGAGCTCGATGATGATGAGGACTTACCTGAG
CCAGATGAAGAAGATGATGAGAATGAAGATGACAATCAGGAGGACCAAGAATACGAGGAGGTTATGATTCTGAGACGCCCATCCCTGCAA
CGTCGAGCTGGCTCCCGCTCTGATGTAACGCATCATGCTGTTACCTCGCAGCTACCACAGGTACCTGCTGGAGCAGGGAGCCGACCTATT
GGGGAGCAGGAAGAAGAAGAGTACGAAACTAAAGGAGGACGCCGGAGAACATGGGATGATGATTATGTGCTAAAGAGACAGTTTTCTGCA
TTGGTTCCTGCTTTTGATCCTAGACCTGGTCGTACTAATGTCCAGCAGACAACTGATCTAGAAATACCACCCCCAGGGACCCCTCATTCA
GAGCTCTTGGAAGAAGTCGAATGTACTCCGTCACCTCGATTAGCTCTCACTTTGAAAGTAACAGGTCTTGGAACGACTCGTGAAGTTGAA
TTACCACTCACCAATTTCAGATCAACCATCTTTTACTATGTACAAAAATTGCTTCAATTGTCCTGTAATGGCAATGTGAAATCAGATAAA
CTTAGGCGTATTTGGGAGCCCACATACACAATCATGTACAGAGAAATGAAGGATTCTGATAAAGAAAAGGAAAATGGAAAAATGGGTTGC
TGGTCTATAGAGCATGTGGAGCAGTACCTTGGCACTGATGAATTACCAAAGAATGACTTGATAACCTACCTGCAGAAGAATGCAGACGCT
GCTTTCCTGCGCCACTGGAAATTAACTGGCACTAATAAAAGTATTAGGAAAAACAGAAATTGTTCTCAGCTCATAGCTGCATATAAGGAT
TTTTGTGAGCATGGAACAAAGTCTGGGTTAAACCAGGGGGCCATTTCTACTCTTCAAAGTAGTGATATTCTTAATTTAACAAAAGAACAA
CCTCAGGCCAAAGCAGGCAATGGACAGAACTCTTGTGGAGTAGAAGATGTCCTTCAGCTTCTGCGTATTCTATATATAGTTGCAAGTGAC
CCTTATTCAAGAATATCCCAGGAAGATGGTGATGAACAGCTTCAGTTTACTTTTCCACCAGATGAATTCACTAGCAAAAAAATTACAACA
AAAATATTACAGCAGATTGAGGAACCATTGGCACTGGCAAGTGGGGCTCTGCCAGACTGGTGTGAACAATTAACCAGCAAATGTCCTTTT
CTAATACCATTTGAAACTAGACAGCTTTATTTCACATGTACAGCATTTGGCGCCTCAAGAGCAATAGTATGGTTACAGAACCGACGTGAA
GCCACTGTGGAGCGAACGAGAACCACAAGCAGTGTTAGGCGAGATGACCCTGGAGAGTTTCGAGTTGGTCGTCTCAAGCATGAAAGAGTA
AAAGTTCCACGTGGCGAGTCACTGATGGAATGGGCTGAGAATGTCATGCAAATACATGCAGATCGGAAATCAGTTCTTGAGGTTGAATTT
TTAGGAGAAGAAGGAACTGGCTTGGGACCCACATTAGAGTTTTATGCTCTGGTGGCAGCAGAATTCCAGAGAACTGACTTGGGAGCTTGG
CTTTGTGATGATAATTTTCCAGATGATGAATCTCGTCACGTTGATCTTGGAGGTGGATTGAAACCTCCTGGATATTATGTGCAGAGGTCA
TGTGGACTGTTCACAGCACCATTTCCACAGGATAGTGATGAGCTTGAAAGGATCACGAAACTGTTTCATTTCCTTGGAATTTTCTTGGCC
AAATGCATTCAAGACAATAGACTTGTGGACTTACCTATTTCTAAACCTTTTTTTAAACTTATGTGTATGGGTGACATTAAAAGCAATATG
AGTAAACTGATTTATGAGTCACGAGGTGATAGAGACTTACACTGTACTGAAAGTCAGTCTGAAGCTTCTACAGAAGAAGGTCATGATTCA
CTCTCGGTAGGAAGCTTTGAAGAGGATTCAAAATCAGAATTTATTCTTGATCCCCCTAAACCAAAACCCCCAGCTTGGTTTAATGGAATT
TTGACTTGGGAAGACTTTGAATTAGTAAACCCACACAGAGCCAGATTTTTAAAAGAAATTAAAGACCTTGCTATCAAGAGGCGCCAAATT
TTAAGCAACAAAGGTCTTTCTGAAGATGAGAAGAACACAAAATTACAGGAACTAGTGCTGAAGAATCCATCAGGTTCTGGGCCTCCACTT
AGCATAGAGGATTTAGGTTTAAATTTCCAGTTTTGCCCTTCCTCAAGAATATATGGTTTTACAGCTGTGGATCTCAAGCCAAGTGGTGAA
GATGAGATGATAACAATGGATAATGCAGAAGAATATGTGGATTTGATGTTTGACTTTTGTATGCATACGGGTATTCAGAAACAAATGGAA
GCCTTTAGAGATGGGTTTAATAAAGTTTTTCCAATGGAGAAATTAAGTTCCTTCAGCCATGAAGAAGTCCAAATGATTCTTTGTGGAAAC
CAGTCACCATCCTGGGCAGCAGAGGATATTATCAATTACACTGAACCTAAGCTGGGTTATACACGTGACAGCCCTGGTTTCCTGAGGTTT
GTGAGGGTTTTATGTGGCATGTCTTCTGATGAAAGGAAAGCATTCTTGCAGTTTACCACTGGTTGTTCAACTCTACCCCCAGGTGGACTG
GCTAACCTGCATCCCAGGCTCACGGTTGTACGCAAGGTTGATGCTACTGATGCAAGCTATCCATCAGTCAATACATGTGTGCATTACCTT
AAGTTGCCTGAATATTCTTCCGAGGAGATCATGAGAGAGCGCCTGCTAGCTGCTACAATGGAGAAAGGCTTTCATCTCAATTGAGCTTTG
AAGTGCAATGGGAGACATCAGAGACTTTAAAAATACTAGTGAAGCCTCTTGTGTTTGTGTGCAGAGAAGTATATGATCCACCATGCTAAT
GACACTTGCCTTTTTTTCCACCATTAAGGCTTTAAGAACATGTGGAATAAGTTTTTTAGCTGCTAATGACAAAACAAATCCTGTAACTAC
CCAGCCAGCAAGTATATAGCACAGAACACTGTGTTACTTTACAAGGGCTTATGTGACTGGAATAAGGTGGTCCCACTTGACTGTTCCAAA
GAGCAGCTTCTCAGATCTTCAGTGTTCACTGGTAAATTTCTAACAGTGTATTTGTGTAAAGTTTGTCATTTCATACTCCATACACTACAG
TTGCTGTCACTGATCCCTGTTTTGCTGGCTTTTAAGCTACTTGGTCAAAAATCCTGCTTCCTTAAAACATAGAGAATTAATGAGCATCTC
AAGCTTTTTCTTTTCCTTTTTAATGATGCCTGCACTATCAAGAGTATTCTAGTGTTCTCTCTTTGTTTGGCATATAATCATGCACCAAAC
TTTTTATTTCTTTAAGGTGGGAGTATATTTTTATTTCCTAAATGCCATACTATGAAGATCAAAGTCTTAAGTGTGTTTGCAGCTCAAAAA
TAAAGATGTATTAAGGGGGGAAAACCTGGTCTAAGTGCAAGGCACACTTACAGCGAGTTTTACTTTCGGTTGTATTTTCTTTGTATATTA

>35963_35963_1_HEATR5A-HECTD1_HEATR5A_chr14_31771501_ENST00000389961_HECTD1_chr14_31602620_ENST00000399332_length(amino acids)=3177AA_BP=0
MELAHSLLLNEEAYNQLGEVQKAEFIFEWLRYLEKLLLATSRNDVREKQKTLVEQLLSLLNSSPGPPTRKLLAKNLAILYSIGDTFSVHE
AIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILGNTFTDTVGNILKAMKSAESQGRYEIMLSLQNILNGLGAAAAPCHRDVYK
AARSCLTDRSMAVRCAAAKNEAIFMWSTDLDSVATLCFKSFEGSNYDVRISVSKLLGIILAKAVISKHPGTAASRQSIRRVSLEEVLELL
GTGFLRGSSGFLRASGDMLKGTSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNFAAFFSHILSLASPSHPKATQTQIDAVCCRRCVSFILR
TTIGGLLGEKAQLAAVKDICQAIWKLKKVMDAVMSDGNLETRLGSTDVAASQHMLVCALQELGNLIHNLGTTAAPLLQDSSTGLLDSILS
VILHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLTGHKSSPEAVTGFSFAVAALLGAVKHCPLGIPHGKGKIIMTLAEDLLCSAA
QNSRLSAQRTQAGWLLISALMTLGPAVVSHHLARVLLLWKCVFPASPKDLETEKSRGDSFTWQVTLEGRAGALCAIKSFVSHCGDLLTEE
VTQRLLPPLPCAVDLLTQLSSILKMYGSPLKTPSVVYRQRLYELLILLPPETYEGNLCAILRELAADLTAPDIQVAASTFLLPPLCHQDD
LLILSPFLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPALSVISSASKLFGVVCAHVGETQRLLILEQLLDSIK
HTKGARQQVVQLHVVSSVSSFLKYVAGSKGCLGPEEMKRFALTLVMGALESPNPLLRCAAAESWARLAQVVDDGAFTAGLAQVSFDKLKS
ARDVVTRTGHSLALGSLHRYLGGISSSQHLNSCIGILYTLAQDSTSPDVQTWALHSLSLIIDSAGPLYYVHVEPTLSLIIMLLLNVPPTH
AEVHQSLGRCLNALITTLGPELQGNSTSISTLRTSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVNLCSPYLLL
RRAVLACLRQLVQREAAEVSEHAVMLAKDSREELTPDANIREVGLEGALLILLDKETDERLCHDIKETLNYMLTSMAVEKLSLWLKLCKD
VLAASADFTAVTCVDTMQEEEGDKGDDASVLTTRRDEKSHPFTNPRWATRVFAAECVCRIINQCENANSAHFDIALAQEMKKRDSRNDFL
VLHLADLIRMAFMAATDHSDQLRLSGLEMLLVVIRRFATVPEPEFPGHVILEQYQANVGAALRPAFTSETPPDVTAKACQVCSAWIASGV
VSDLNDLRRVHQLLVSSLTKIQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKNHRQPLKTTTCLEDGIRNGSCSSDGLLDLV
YADLGTLSRLWLAALQDFALLTLPSEFASQLPAEGGAFYTAETSENAKLHYYNSWALILHATALWLTSTGFVVADPDEGASNLSRPVTPT
SMCQGSSSGATIKSPEDVYTDRFHLILGISVEFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELLNVLHRVILTRESP
SIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGSPGVKAT
KPQILLEDGSRLVSAALVILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQALKGILSSPMARAEKSRTAWTD
LLRSALTTILDCWDPGKAAKEAEANLRRQRRLVRSQVLKYMVPGARVIRGLDWKWRDQDGSPQGEGTVTGELHNGWIDVTWDAGGSNSYR
MGAEGKFDLKLAPGYDPDTVASPKPVSSTVSGTTQSWSSLVKNNCPDKTSAAAGSSSRKGSSSSVCSVASSSDISLGSTKTERRSEIVME
HSIVSGADVHEPIVVLSSAENVPQTEVGSSSSASTSTLTAETGSENAERKLGPDSSVRTPGESSAISMGIVSVSSPDVSSVSELTNKEAA
SQRPLSSSASNRLSVSSLLAAGAPMSSSASVPNLSSRETSSLESFVRRVANIARTNATNNMNLSRSSSDNNTNTLGRNVMSTATSPLMGA
QSFPNLTTPGTTSTVTMSTSSVTSSSNVATATTVLSVGQSLSNTLTTSLTSTSSESDTGQEAEYSLYDFLDSCRASTLLAELDDDEDLPE
PDEEDDENEDDNQEDQEYEEVMILRRPSLQRRAGSRSDVTHHAVTSQLPQVPAGAGSRPIGEQEEEEYETKGGRRRTWDDDYVLKRQFSA
LVPAFDPRPGRTNVQQTTDLEIPPPGTPHSELLEEVECTPSPRLALTLKVTGLGTTREVELPLTNFRSTIFYYVQKLLQLSCNGNVKSDK
LRRIWEPTYTIMYREMKDSDKEKENGKMGCWSIEHVEQYLGTDELPKNDLITYLQKNADAAFLRHWKLTGTNKSIRKNRNCSQLIAAYKD
FCEHGTKSGLNQGAISTLQSSDILNLTKEQPQAKAGNGQNSCGVEDVLQLLRILYIVASDPYSRISQEDGDEQLQFTFPPDEFTSKKITT
KILQQIEEPLALASGALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDDPGEFRVGRLKHERV
KVPRGESLMEWAENVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGAWLCDDNFPDDESRHVDLGGGLKPPGYYVQRS
CGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEASTEEGHDS
LSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIKDLAIKRRQILSNKGLSEDEKNTKLQELVLKNPSGSGPPL
SIEDLGLNFQFCPSSRIYGFTAVDLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGN
QSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYL

--------------------------------------------------------------
>35963_35963_2_HEATR5A-HECTD1_HEATR5A_chr14_31771501_ENST00000389961_HECTD1_chr14_31602620_ENST00000553700_length(transcript)=10346nt_BP=5446nt
ATGGAATTAGCTCATAGCTTACTGCTGAATGAAGAAGCATACAATCAACTAGGTGAAGTTCAGAAGGCAGAGTTTATTTTTGAGTGGTTG
AGATACTTGGAGAAGCTCTTGTTGGCAACCAGCAGGAATGATGTAAGGGAGAAACAGAAGACTCTTGTTGAACAGCTCCTGTCTTTGTTG
AACAGCTCCCCAGGGCCTCCTACCCGCAAACTGCTTGCTAAGAATCTAGCCATACTTTATAGTATTGGAGACACATTCTCCGTTCATGAA
GCAATCGATAAATGTAATGATCTTATTCGTAGCAAAGATGATTCTCCAAGTTATCTTCCCACTAAGCTTGCTGCTGTGGTATGTTTGGGT
TCCTTGTACAAGAAGTTGGGTAGAATACTGGGTAACACCTTTACTGATACAGTGGGGAATATTCTTAAAGCTATGAAGAGTGCAGAGTCT
CAAGGCCGATATGAGATTATGCTAAGTCTGCAAAATATATTGAATGGACTAGGAGCTGCCGCTGCACCTTGTCACAGGGATGTTTATAAA
GCTGCTAGATCCTGCTTGACAGATAGATCCATGGCTGTTCGTTGTGCTGCTGCAAAGAATGAAGCCATCTTTATGTGGAGTACGGACCTG
GACAGTGTGGCCACACTGTGTTTTAAGTCCTTTGAAGGTTCCAATTATGATGTGCGGATTTCTGTTTCAAAGTTACTAGGCATAATATTA
GCTAAAGCTGTAATTTCTAAACATCCAGGAACAGCAGCCTCACGTCAAAGCATTCGCAGAGTATCTTTGGAGGAAGTTCTGGAATTACTA
GGAACAGGGTTTCTACGTGGGAGTTCAGGATTCCTTCGAGCCAGTGGAGATATGCTGAAAGGAACCAGTTCAGTCAGTAGGGATGTTCGA
GTTGGAGTTACTCAGGCTTATGTGGTATTTGTTTCAACACTAGGAGGAGCTTGGCTAGAGAAAAATTTTGCTGCCTTTTTTTCTCATATC
CTAAGCCTTGCGTCACCGTCACACCCTAAAGCCACCCAAACTCAGATCGATGCCGTCTGCTGTCGCCGTTGTGTTTCATTTATTCTTCGA
ACTACTATAGGTGGTCTTCTTGGAGAAAAGGCTCAGCTTGCTGCTGTAAAGGATATTTGCCAGGCCATCTGGAAGCTAAAGAAAGTTATG
GATGCCGTAATGAGTGATGGTAATTTGGAAACCCGGCTTGGTTCCACAGATGTAGCCGCTAGCCAACATATGCTGGTTTGTGCTTTACAA
GAACTTGGAAATCTCATACACAATCTTGGCACCACAGCGGCACCTTTGCTACAGGATTCAAGTACAGGTCTCCTTGACAGTATCTTGTCA
GTTATTCTTCATCCTAGCATTTCTGTTCGACTAGCAGCAGCTTGGTGTTTACACTGCATTGCCGTGGCATTACCCTCCTACCTAACACCA
CTCTTGGATCGTTGCCTTGAACGGCTTACTGGACATAAGTCTTCACCTGAAGCAGTGACTGGCTTCAGTTTTGCTGTAGCAGCTTTGTTG
GGAGCAGTAAAACATTGTCCTTTAGGAATTCCTCATGGAAAAGGCAAGATTATTATGACATTAGCAGAGGATTTGCTGTGTTCTGCTGCT
CAAAACAGTCGCCTTTCAGCTCAGCGCACACAAGCTGGATGGTTGCTGATTTCTGCTCTGATGACATTAGGTCCTGCAGTTGTTAGCCAT
CACCTTGCTCGAGTTCTGCTGTTGTGGAAGTGTGTCTTTCCAGCATCTCCTAAAGATCTAGAAACAGAAAAGAGCCGAGGAGATTCGTTT
ACATGGCAGGTGACCCTGGAAGGACGAGCTGGTGCACTGTGTGCTATCAAGAGCTTTGTTTCCCACTGTGGTGATCTTCTTACTGAGGAA
GTAACTCAGCGTCTTCTTCCACCACTTCCTTGTGCTGTGGATTTGCTAACTCAGCTTTCTTCAATACTAAAAATGTATGGAAGTCCTTTG
AAAACACCGTCAGTGGTTTATAGACAAAGACTTTATGAACTGTTGATTTTATTACCTCCTGAGACCTATGAAGGAAACCTCTGTGCTATC
CTCAGAGAGCTGGCTGCTGACTTGACTGCCCCTGATATTCAGGTGGCAGCATCTACATTTTTACTTCCACCCCTCTGTCATCAGGATGAT
CTTTTGATACTAAGTCCTTTCCTACAAGAGACTGACCATAGATTTATTGAAGAACAGCTCCTGCTTGGTAATGGTGTTGCTTGCGGAAGT
CTTGAATATGACCCTTATTCGATTTATGAGAAAGATGTAGAGGGAGATTCAGTGCCTAAGCCCTTACCTCCAGCACTATCAGTTATTAGT
TCTGCATCCAAGCTCTTTGGGGTTGTATGCGCTCATGTGGGAGAAACTCAAAGGCTTCTTATATTGGAACAGCTTTTGGACAGTATAAAG
CACACAAAAGGAGCTCGTCAGCAAGTGGTTCAGTTACATGTTGTTTCTTCAGTTTCTAGTTTCTTGAAGTACGTGGCTGGCTCCAAGGGA
TGTTTAGGTCCAGAAGAAATGAAAAGATTTGCCTTAACATTAGTTATGGGAGCCCTAGAAAGCCCCAACCCCTTGCTGAGATGTGCAGCT
GCAGAGTCATGGGCTAGATTAGCCCAAGTGGTAGATGATGGAGCTTTTACTGCTGGATTAGCTCAAGTTAGCTTTGACAAATTGAAATCA
GCAAGGGATGTGGTTACCAGAACAGGACACTCATTGGCCTTGGGGTCCCTACATAGGTATTTAGGAGGAATAAGTTCTTCTCAACACCTA
AATTCTTGTATTGGAATCCTTTATACTTTGGCGCAGGACAGCACTTCTCCTGATGTGCAGACCTGGGCATTACATTCTCTATCATTGATC
ATTGATTCTGCTGGCCCACTCTATTATGTGCATGTGGAACCTACCCTTTCTCTTATTATAATGTTGTTGTTAAATGTGCCTCCTACTCAT
GCTGAAGTTCACCAAAGCCTTGGTCGCTGTTTGAATGCCCTTATTACCACGTTAGGTCCAGAGCTACAAGGTAACAGTACTTCAATTTCT
ACCTTAAGGACTTCCTGTCTACTGGGTTGTGCAGTAATGCAAGATAACCCAGACTGCCTTGTTCAAGCTCAGGCCATCTCTTGCCTTCAG
CAGCTTCATATGTTTGCTCCACGACATGTCAACTTGTCTAGCCTGGTTAGCTGCCTCTGTGTGAATCTTTGTAGCCCCTACTTGTTACTG
AGAAGAGCAGTACTGGCTTGCTTACGTCAGCTTGTACAAAGAGAAGCAGCTGAAGTTTCAGAACATGCTGTTATGCTTGCTAAGGATAGC
AGAGAAGAGTTGACTCCAGATGCTAACATCAGAGAAGTTGGCCTTGAGGGGGCATTGTTGATCTTACTAGACAAGGAGACAGATGAGAGA
TTATGCCATGATATCAAAGAGACTTTAAATTATATGCTTACATCTATGGCAGTGGAAAAACTCTCCCTGTGGTTAAAGCTTTGTAAAGAT
GTACTTGCTGCATCAGCTGATTTTACAGCTGTAACTTGTGTGGATACAATGCAAGAAGAAGAAGGAGATAAAGGGGATGATGCCTCAGTC
CTGACCACCAGACGTGATGAAAAATCCCATCCTTTTACCAATCCCCGATGGGCTACTAGAGTCTTTGCTGCTGAATGTGTCTGTAGGATA
ATTAACCAATGTGAGAATGCTAACAGTGCACATTTTGACATTGCTTTAGCACAAGAAATGAAAAAAAGAGATTCAAGAAATGACTTTTTG
GTACTGCATCTTGCTGACTTAATTCGCATGGCTTTTATGGCTGCCACAGATCACAGTGACCAGCTCCGTCTTTCTGGCCTTGAAATGCTG
TTAGTTGTTATTCGGCGATTTGCAACTGTTCCAGAACCAGAGTTTCCAGGTCATGTGATTCTGGAACAGTATCAAGCCAATGTAGGAGCA
GCGCTTAGACCAGCCTTCACTTCAGAGACACCACCTGATGTCACTGCCAAAGCATGTCAGGTTTGCAGTGCCTGGATAGCAAGTGGAGTT
GTAAGTGACCTTAATGATCTCCGAAGAGTTCATCAGTTGCTTGTTTCATCGTTAACTAAAATACAGGCTGGAAAAGAAGCTCTAAGTCAC
TTATATAATGAAAGTGCTTCTACCATGGAGATCTTAGCTGTGCTTAAAGCCTGGGCAGAGGTCTACATAATTGCTGTGCAAAGACATAAA
AACCACAGACAACCTTTGAAGACTACCACCTGTTTAGAAGACGGTATCAGAAATGGATCATGTTCATCAGATGGACTGCTTGACTTAGTC
TATGCAGATCTTGGCACACTAAGCAGACTCTGGCTTGCTGCACTTCAGGATTTTGCTCTTTTAACTTTGCCTTCAGAATTTGCCTCCCAA
CTTCCTGCTGAAGGTGGTGCTTTCTACACAGCAGAGACTAGTGAAAATGCAAAATTGCATTATTACAACTCCTGGGCACTTATCCTCCAT
GCTACAGCATTGTGGCTTACAAGCACGGGTTTTGTTGTTGCTGACCCAGATGAAGGAGCATCTAATCTCTCCAGGCCTGTAACACCAACT
TCCATGTGTCAGGGTTCATCATCTGGGGCTACCATAAAGTCCCCTGAGGATGTCTACACTGATAGATTCCATCTTATTTTAGGAATCAGC
GTGGAATTTCTATGTTCCTTACGTTCAGATGCAACCATGGAAAGCATAACTGCTTGTTTACATGCATTGCAAGCACTTCTAGATGTACCT
TGGCCCAGATCAAAAATTGGCAGTGATCAGGACTTGGGTATAGAATTGCTGAATGTTCTACATCGAGTAATTTTAACCAGAGAATCACCT
TCCATTCAGTTGGCTTCACTTGAAGTGGTAAGGCAGATTATCTGTGCTGCTCAAGAACATGTGAAGGAAAAAAGACGAAGTGCAGAAGTT
GATGATGGGGCTGCTGAAAAGGAAACTCTGCCAGAGTTTGGAGAGGGAAAGGACACCGGAGGACTTGTGCCTGGAAAGTCTTTGGTCTTT
GCAACACTGGAATTGTGTGTATGCATTCTAGTTAGACAGCTCCCAGAATTAAACCCTAAATTGACAGGTAGCCCAGGAGTAAAAGCTACG
AAGCCACAGATACTATTAGAAGATGGAAGTAGATTGGTTTCAGCTGCATTGGTTATCCTTTCCGAACTTCCTGCAGTGTGCTCTCCTGAA
GGAAGCATCTCAATTCTCCCTACTATATTGTACCTCACAATCGGGGTCCTCAGAGAGACTGCTGTGAAGTTACCTGGGGGCCAGTTATCT
TCGACAGTTGCAGCTTCCCTACAGGCTCTAAAAGGAATATTATCTTCTCCCATGGCCCGGGCAGAAAAGAGCCGTACTGCTTGGACTGAC
CTTCTCCGAAGTGCCTTAACAACAATTCTTGACTGTTGGGATCCAGGGAAAGCAGCTAAAGAAGCAGAAGCTAATCTTAGACGGCAGAGA
CGTCTAGTACGTTCCCAGGTTCTGAAATACATGGTTCCAGGAGCTCGTGTTATCAGAGGCCTGGATTGGAAATGGCGAGATCAGGATGGC
AGCCCACAGGGAGAAGGCACTGTCACAGGAGAACTACACAATGGCTGGATTGATGTCACCTGGGATGCTGGTGGCTCAAACTCTTACCGT
ATGGGCGCAGAAGGAAAATTTGACCTCAAGCTTGCACCAGGGTACGACCCTGATACAGTGGCATCACCCAAACCTGTTTCATCCACTGTT
TCAGGCACAACGCAATCATGGAGCAGCTTGGTGAAAAACAACTGTCCAGACAAGACATCTGCTGCTGCAGGCTCCTCAAGTAGAAAAGGA
AGCAGCAGTTCTGTGTGTAGCGTGGCCAGTAGCAGCGACATCAGCTTGGGTTCGACCAAAACGGAACGGAGATCAGAAATTGTAATGGAA
CACAGTATAGTTTCAGGAGCTGATGTCCATGAACCAATTGTTGTTCTTTCATCTGCTGAAAACGTCCCTCAAACAGAAGTAGGGTCATCT
TCCAGTGCAAGCACCAGCACCTTAACAGCGGAAACGGGAAGTGAAAATGCTGAAAGGAAGTTAGGCCCTGATAGTTCTGTTCGTACTCCT
GGGGAGTCTAGTGCAATATCCATGGGAATTGTCAGTGTTAGTTCTCCTGATGTTAGTTCAGTATCTGAATTAACTAATAAAGAAGCAGCT
TCACAACGACCTCTTAGCTCTTCAGCAAGTAACAGACTGTCAGTGAGTTCTTTGTTGGCTGCTGGGGCCCCTATGAGCTCTAGTGCAAGT
GTACCTAACCTGTCCTCAAGAGAAACATCTAGCTTGGAGAGTTTTGTAAGGAGAGTGGCAAACATAGCACGGACTAATGCCACGAACAAC
ATGAATCTAAGCCGAAGCAGCAGTGATAACAACACTAATACTTTGGGGAGGAATGTGATGAGCACAGCAACTTCTCCTCTTATGGGTGCT
CAGAGTTTCCCTAATTTGACCACACCTGGTACTACATCAACAGTGACTATGTCAACATCCAGTGTTACTAGCAGCAGCAATGTAGCTACA
GCAACAACAGTTTTATCAGTTGGTCAATCTTTAAGTAACACTTTAACCACCAGCCTCACATCAACTTCCAGTGAGAGTGACACAGGTCAG
GAAGCAGAATATTCCTTATATGATTTCCTTGATAGCTGCCGTGCCAGTACTCTATTGGCTGAGCTCGATGATGATGAGGACTTACCTGAG
CCAGATGAAGAAGATGATGAGAATGAAGATGACAATCAGGAGGACCAAGAATACGAGGAGGTTATGATTCTGAGACGCCCATCCCTGCAA
CGTCGAGCTGGCTCCCGCTCTGATGTAACGCATCATGCTGTTACCTCGCAGCTACCACAGGTACCTGCTGGAGCAGGGAGCCGACCTATT
GGGGAGCAGGAAGAAGAAGAGTACGAAACTAAAGGAGGACGCCGGAGAACATGGGATGATGATTATGTGCTAAAGAGACAGTTTTCTGCA
TTGGTTCCTGCTTTTGATCCTAGACCTGGTCGTACTAATGTCCAGCAGACAACTGATCTAGAAATACCACCCCCAGGGACCCCTCATTCA
GAGCTCTTGGAAGAAGTCGAATGTACTCCGTCACCTCGATTAGCTCTCACTTTGAAAGTAACAGGTCTTGGAACGACTCGTGAAGTTGAA
TTACCACTCACCAATTTCAGATCAACCATCTTTTACTATGTACAAAAATTGCTTCAATTGTCCTGTAATGGCAATGTGAAATCAGATAAA
CTTAGGCGTATTTGGGAGCCCACATACACAATCATGTACAGAGAAATGAAGGATTCTGATAAAGAAAAGGAAAATGGAAAAATGGGTTGC
TGGTCTATAGAGCATGTGGAGCAGTACCTTGGCACTGATGAATTACCAAAGAATGACTTGATAACCTACCTGCAGAAGAATGCAGACGCT
GCTTTCCTGCGCCACTGGAAATTAACTGGCACTAATAAAAGTATTAGGAAAAACAGAAATTGTTCTCAGCTCATAGCTGCATATAAGGAT
TTTTGTGAGCATGGAACAAAGTCTGGGTTAAACCAGGGGGCCATTTCTACTCTTCAAAGTAGTGATATTCTTAATTTAACAAAAGAACAA
CCTCAGGCCAAAGCAGGCAATGGACAGAACTCTTGTGGAGTAGAAGATGTCCTTCAGCTTCTGCGTATTCTATATATAGTTGCAAGTGAC
CCTTATTCAAGAATATCCCAGGAAGATGGTGATGAACAGCTTCAGTTTACTTTTCCACCAGATGAATTCACTAGCAAAAAAATTACAACA
AAAATATTACAGCAGATTGAGGAACCATTGGCACTGGCAAGTGGGGCTCTGCCAGACTGGTGTGAACAATTAACCAGCAAATGTCCTTTT
CTAATACCATTTGAAACTAGACAGCTTTATTTCACATGTACAGCATTTGGCGCCTCAAGAGCAATAGTATGGTTACAGAACCGACGTGAA
GCCACTGTGGAGCGAACGAGAACCACAAGCAGTGTTAGGCGAGATGACCCTGGAGAGTTTCGAGTTGGTCGTCTCAAGCATGAAAGAGTA
AAAGTTCCACGTGGCGAGTCACTGATGGAATGGGCTGAGAATGTCATGCAAATACATGCAGATCGGAAATCAGTTCTTGAGGTTGAATTT
TTAGGAGAAGAAGGAACTGGCTTGGGACCCACATTAGAGTTTTATGCTCTGGTGGCAGCAGAATTCCAGAGAACTGACTTGGGAGCTTGG
CTTTGTGATGATAATTTTCCAGATGATGAATCTCGTCACGTTGATCTTGGAGGTGGATTGAAACCTCCTGGATATTATGTGCAGAGGTCA
TGTGGACTGTTCACAGCACCATTTCCACAGGATAGTGATGAGCTTGAAAGGATCACGAAACTGTTTCATTTCCTTGGAATTTTCTTGGCC
AAATGCATTCAAGACAATAGACTTGTGGACTTACCTATTTCTAAACCTTTTTTTAAACTTATGTGTATGGGTGACATTAAAAGCAATATG
AGTAAACTGATTTATGAGTCACGAGGTGATAGAGACTTACACTGTACTGAAAGTCAGTCTGAAGCTTCTACAGAAGAAGGTCATGATTCA
CTCTCGGTAGGAAGCTTTGAAGAGGATTCAAAATCAGAATTTATTCTTGATCCCCCTAAACCAAAACCCCCAGCTTGGTTTAATGGAATT
TTGACTTGGGAAGACTTTGAATTAGTAAACCCACACAGAGCCAGATTTTTAAAAGAAATTAAAGACCTTGCTATCAAGAGGCGCCAAATT
TTAAGCAACAAAGGTCTTTCTGAAGATGAGAAGAACACAAAATTACAGGAACTAGTGCTGAAGAATCCATCAGGTTCTGGGCCTCCACTT
AGCATAGAGGATTTAGGTTTAAATTTCCAGTTTTGCCCTTCCTCAAGAATATATGGTTTTACAGCTGTGGATCTCAAGCCAAGTGGTGAA
GATGAGATGATAACAATGGATAATGCAGAAGAATATGTGGATTTGATGTTTGACTTTTGTATGCATACGGGTATTCAGAAACAAATGGAA
GCCTTTAGAGATGGGTTTAATAAAGTTTTTCCAATGGAGAAATTAAGTTCCTTCAGCCATGAAGAAGTCCAAATGATTCTTTGTGGAAAC
CAGTCACCATCCTGGGCAGCAGAGGATATTATCAATTACACTGAACCTAAGCTGGGTTATACACGTGACAGCCCTGGTTTCCTGAGGTTT
GTGAGGGTTTTATGTGGCATGTCTTCTGATGAAAGGAAAGCATTCTTGCAGTTTACCACTGGTTGTTCAACTCTACCCCCAGGTGGACTG
GCTAACCTGCATCCCAGGCTCACGGTTGTACGCAAGGTTGATGCTACTGATGCAAGCTATCCATCAGTCAATACATGTGTGCATTACCTT
AAGTTGCCTGAATATTCTTCCGAGGAGATCATGAGAGAGCGCCTGCTAGCTGCTACAATGGAGAAAGGCTTTCATCTCAATTGAGCTTTG
AAGTGCAATGGGAGACATCAGAGACTTTAAAAATACTAGTGAAGCCTCTTGTGTTTGTGTGCAGAGAAGTATATGATCCACCATGCTAAT
GACACTTGCCTTTTTTTCCACCATTAAGGCTTTAAGAACATGTGGAATAAGTTTTTTAGCTGCTAATGACAAAACAAATCCTGTAACTAC
CCAGCCAGCAAGTATATAGCACAGAACACTGTGTTACTTTACAAGGGCTTATGTGACTGGAATAAGGTGGTCCCACTTGACTGTTCCAAA
GAGCAGCTTCTCAGATCTTCAGTGTTCACTGGTAAATTTCTAACAGTGTATTTGTGTAAAGTTTGTCATTTCATACTCCATACACTACAG
TTGCTGTCACTGATCCCTGTTTTGCTGGCTTTTAAGCTACTTGGTCAAAAATCCTGCTTCCTTAAAACATAGAGAATTAATGAGCATCTC
AAGCTTTTTCTTTTCCTTTTTAATGATGCCTGCACTATCAAGAGTATTCTAGTGTTCTCTCTTTGTTTGGCATATAATCATGCACCAAAC
TTTTTATTTCTTTAAGGTGGGAGTATATTTTTATTTCCTAAATGCCATACTATGAAGATCAAAGTCTTAAGTGTGTTTGCAGCTCAAAAA
TAAAGATGTATTAAGGGGGGAAAACCTGGTCTAAGTGCAAGGCACACTTACAGCGAGTTTTACTTTCGGTTGTATTTTCTTTGTATATTA

>35963_35963_2_HEATR5A-HECTD1_HEATR5A_chr14_31771501_ENST00000389961_HECTD1_chr14_31602620_ENST00000553700_length(amino acids)=3177AA_BP=0
MELAHSLLLNEEAYNQLGEVQKAEFIFEWLRYLEKLLLATSRNDVREKQKTLVEQLLSLLNSSPGPPTRKLLAKNLAILYSIGDTFSVHE
AIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILGNTFTDTVGNILKAMKSAESQGRYEIMLSLQNILNGLGAAAAPCHRDVYK
AARSCLTDRSMAVRCAAAKNEAIFMWSTDLDSVATLCFKSFEGSNYDVRISVSKLLGIILAKAVISKHPGTAASRQSIRRVSLEEVLELL
GTGFLRGSSGFLRASGDMLKGTSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNFAAFFSHILSLASPSHPKATQTQIDAVCCRRCVSFILR
TTIGGLLGEKAQLAAVKDICQAIWKLKKVMDAVMSDGNLETRLGSTDVAASQHMLVCALQELGNLIHNLGTTAAPLLQDSSTGLLDSILS
VILHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLTGHKSSPEAVTGFSFAVAALLGAVKHCPLGIPHGKGKIIMTLAEDLLCSAA
QNSRLSAQRTQAGWLLISALMTLGPAVVSHHLARVLLLWKCVFPASPKDLETEKSRGDSFTWQVTLEGRAGALCAIKSFVSHCGDLLTEE
VTQRLLPPLPCAVDLLTQLSSILKMYGSPLKTPSVVYRQRLYELLILLPPETYEGNLCAILRELAADLTAPDIQVAASTFLLPPLCHQDD
LLILSPFLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPALSVISSASKLFGVVCAHVGETQRLLILEQLLDSIK
HTKGARQQVVQLHVVSSVSSFLKYVAGSKGCLGPEEMKRFALTLVMGALESPNPLLRCAAAESWARLAQVVDDGAFTAGLAQVSFDKLKS
ARDVVTRTGHSLALGSLHRYLGGISSSQHLNSCIGILYTLAQDSTSPDVQTWALHSLSLIIDSAGPLYYVHVEPTLSLIIMLLLNVPPTH
AEVHQSLGRCLNALITTLGPELQGNSTSISTLRTSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVNLCSPYLLL
RRAVLACLRQLVQREAAEVSEHAVMLAKDSREELTPDANIREVGLEGALLILLDKETDERLCHDIKETLNYMLTSMAVEKLSLWLKLCKD
VLAASADFTAVTCVDTMQEEEGDKGDDASVLTTRRDEKSHPFTNPRWATRVFAAECVCRIINQCENANSAHFDIALAQEMKKRDSRNDFL
VLHLADLIRMAFMAATDHSDQLRLSGLEMLLVVIRRFATVPEPEFPGHVILEQYQANVGAALRPAFTSETPPDVTAKACQVCSAWIASGV
VSDLNDLRRVHQLLVSSLTKIQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKNHRQPLKTTTCLEDGIRNGSCSSDGLLDLV
YADLGTLSRLWLAALQDFALLTLPSEFASQLPAEGGAFYTAETSENAKLHYYNSWALILHATALWLTSTGFVVADPDEGASNLSRPVTPT
SMCQGSSSGATIKSPEDVYTDRFHLILGISVEFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELLNVLHRVILTRESP
SIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGSPGVKAT
KPQILLEDGSRLVSAALVILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQALKGILSSPMARAEKSRTAWTD
LLRSALTTILDCWDPGKAAKEAEANLRRQRRLVRSQVLKYMVPGARVIRGLDWKWRDQDGSPQGEGTVTGELHNGWIDVTWDAGGSNSYR
MGAEGKFDLKLAPGYDPDTVASPKPVSSTVSGTTQSWSSLVKNNCPDKTSAAAGSSSRKGSSSSVCSVASSSDISLGSTKTERRSEIVME
HSIVSGADVHEPIVVLSSAENVPQTEVGSSSSASTSTLTAETGSENAERKLGPDSSVRTPGESSAISMGIVSVSSPDVSSVSELTNKEAA
SQRPLSSSASNRLSVSSLLAAGAPMSSSASVPNLSSRETSSLESFVRRVANIARTNATNNMNLSRSSSDNNTNTLGRNVMSTATSPLMGA
QSFPNLTTPGTTSTVTMSTSSVTSSSNVATATTVLSVGQSLSNTLTTSLTSTSSESDTGQEAEYSLYDFLDSCRASTLLAELDDDEDLPE
PDEEDDENEDDNQEDQEYEEVMILRRPSLQRRAGSRSDVTHHAVTSQLPQVPAGAGSRPIGEQEEEEYETKGGRRRTWDDDYVLKRQFSA
LVPAFDPRPGRTNVQQTTDLEIPPPGTPHSELLEEVECTPSPRLALTLKVTGLGTTREVELPLTNFRSTIFYYVQKLLQLSCNGNVKSDK
LRRIWEPTYTIMYREMKDSDKEKENGKMGCWSIEHVEQYLGTDELPKNDLITYLQKNADAAFLRHWKLTGTNKSIRKNRNCSQLIAAYKD
FCEHGTKSGLNQGAISTLQSSDILNLTKEQPQAKAGNGQNSCGVEDVLQLLRILYIVASDPYSRISQEDGDEQLQFTFPPDEFTSKKITT
KILQQIEEPLALASGALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDDPGEFRVGRLKHERV
KVPRGESLMEWAENVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGAWLCDDNFPDDESRHVDLGGGLKPPGYYVQRS
CGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEASTEEGHDS
LSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIKDLAIKRRQILSNKGLSEDEKNTKLQELVLKNPSGSGPPL
SIEDLGLNFQFCPSSRIYGFTAVDLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGN
QSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYL

--------------------------------------------------------------
>35963_35963_3_HEATR5A-HECTD1_HEATR5A_chr14_31771501_ENST00000439727_HECTD1_chr14_31602620_ENST00000399332_length(transcript)=9562nt_BP=4662nt
CTTTGGAGGAAGTTCTGGAATTACTAGGAACAGGGTTTCTACGTGGGAGTTCAGGATTCCTTCGAGCCAGTGGAGATATGCTGAAAGGAA
CCAGTTCAGTCAGTAGGGATGTTCGAGTTGGAGTTACTCAGGCTTATGTGGTATTTGTTTCAACACTAGGAGGAGCTTGGCTAGAGAAAA
ATTTTGCTGCCTTTTTTTCTCATATCCTAAGCCTTGCGTCACCGTCACACCCTAAAGCCACCCAAACTCAGATCGATGCCGTCTGCTGTC
GCCGTTGTGTTTCATTTATTCTTCGAACTACTATAGGTGGTCTTCTTGGAGAAAAGGCTCAGCTTGCTGCTGTAAAGGATATTTGCCAGG
CCATCTGGAAGCTAAAGAAAGTTATGGATGCCGTAATGAGTGATGGTAATTTGGAAACCCGGCTTGGTTCCACAGATGTAGCCGCTAGCC
AACATATGCTGGTTTGTGCTTTACAAGAACTTGGAAATCTCATACACAATCTTGGCACCACAGCGGCACCTTTGCTACAGGATTCAAGTA
CAGGTCTCCTTGACAGTATCTTGTCAGTTATTCTTCATCCTAGCATTTCTGTTCGACTAGCAGCAGCTTGGTGTTTACACTGCATTGCCG
TGGCATTACCCTCCTACCTAACACCACTCTTGGATCGTTGCCTTGAACGGCTTACTGGACATAAGTCTTCACCTGAAGCAGTGACTGGCT
TCAGTTTTGCTGTAGCAGCTTTGTTGGGAGCAGTAAAACATTGTCCTTTAGGAATTCCTCATGGAAAAGGCAAGATTATTATGACATTAG
CAGAGGATTTGCTGTGTTCTGCTGCTCAAAACAGTCGCCTTTCAGCTCAGCGCACACAAGCTGGATGGTTGCTGATTTCTGCTCTGATGA
CATTAGGTCCTGCAGTTGTTAGCCATCACCTTGCTCGAGTTCTGCTGTTGTGGAAGTGTGTCTTTCCAGCATCTCCTAAAGATCTAGAAA
CAGAAAAGAGCCGAGGAGATTCGTTTACATGGCAGGTGACCCTGGAAGGACGAGCTGGTGCACTGTGTGCTATCAAGAGCTTTGTTTCCC
ACTGTGGTGATCTTCTTACTGAGGAAGTAACTCAGCGTCTTCTTCCACCACTTCCTTGTGCTGTGGATTTGCTAACTCAGCTTTCTTCAA
TACTAAAAATGTATGGAAGTCCTTTGAAAACACCGTCAGTGGTTTATAGACAAAGACTTTATGAACTGTTGATTTTATTACCTCCTGAGA
CCTATGAAGGAAACCTCTGTGCTATCCTCAGAGAGCTGGCTGCTGACTTGACTGCCCCTGATATTCAGGTGGCAGCATCTACATTTTTAC
TTCCACCCCTCTGTCATCAGGATGATCTTTTGATACTAAGTCCTTTCCTACAAGAGACTGACCATAGATTTATTGAAGAACAGCTCCTGC
TTGGTAATGGTGTTGCTTGCGGAAGTCTTGAATATGACCCTTATTCGATTTATGAGAAAGATGTAGAGGGAGATTCAGTGCCTAAGCCCT
TACCTCCAGCACTATCAGTTATTAGTTCTGCATCCAAGCTCTTTGGGGTTGTATGCGCTCATGTGGGAGAAACTCAAAGGCTTCTTATAT
TGGAACAGCTTTTGGACAGTATAAAGCACACAAAAGGAGCTCGTCAGCAAGTGGTTCAGTTACATGTTGTTTCTTCAGTTTCTAGTTTCT
TGAAGTACGTGGCTGGCTCCAAGGGATGTTTAGGTCCAGAAGAAATGAAAAGATTTGCCTTAACATTAGTTATGGGAGCCCTAGAAAGCC
CCAACCCCTTGCTGAGATGTGCAGCTGCAGAGTCATGGGCTAGATTAGCCCAAGTGGTAGATGATGGAGCTTTTACTGCTGGATTAGCTC
AAGTTAGCTTTGACAAATTGAAATCAGCAAGGGATGTGGTTACCAGAACAGGACACTCATTGGCCTTGGGGTCCCTACATAGGTATTTAG
GAGGAATAAGTTCTTCTCAACACCTAAATTCTTGTATTGGAATCCTTTATACTTTGGCGCAGGACAGCACTTCTCCTGATGTGCAGACCT
GGGCATTACATTCTCTATCATTGATCATTGATTCTGCTGGCCCACTCTATTATGTGCATGTGGAACCTACCCTTTCTCTTATTATAATGT
TGTTGTTAAATGTGCCTCCTACTCATGCTGAAGTTCACCAAAGCCTTGGTCGCTGTTTGAATGCCCTTATTACCACGTTAGGTCCAGAGC
TACAAGGTAACAGTACTTCAATTTCTACCTTAAGGACTTCCTGTCTACTGGGTTGTGCAGTAATGCAAGATAACCCAGACTGCCTTGTTC
AAGCTCAGGCCATCTCTTGCCTTCAGCAGCTTCATATGTTTGCTCCACGACATGTCAACTTGTCTAGCCTGGTTAGCTGCCTCTGTGTGA
ATCTTTGTAGCCCCTACTTGTTACTGAGAAGAGCAGTACTGGCTTGCTTACGTCAGCTTGTACAAAGAGAAGCAGCTGAAGTTTCAGAAC
ATGCTGTTATGCTTGCTAAGGATAGCAGAGAAGAGTTGACTCCAGATGCTAACATCAGAGAAGTTGGCCTTGAGGGGGCATTGTTGATCT
TACTAGACAAGGAGACAGATGAGAGATTATGCCATGATATCAAAGAGACTTTAAATTATATGCTTACATCTATGGCAGTGGAAAAACTCT
CCCTGTGGTTAAAGCTTTGTAAAGATGTACTTGCTGCATCAGCTGATTTTACAGCTGTAACTTGTGTGGATACAATGCAAGAAGAAGAAG
GAGATAAAGGGGATGATGCCTCAGTCCTGACCACCAGACGTGATGAAAAATCCCATCCTTTTACCAATCCCCGATGGGCTACTAGAGTCT
TTGCTGCTGAATGTGTCTGTAGGATAATTAACCAATGTGAGAATGCTAACAGTGCACATTTTGACATTGCTTTAGCACAAGAAATGAAAA
AAAGAGATTCAAGAAATGACTTTTTGGTACTGCATCTTGCTGACTTAATTCGCATGGCTTTTATGGCTGCCACAGATCACAGTGACCAGC
TCCGTCTTTCTGGCCTTGAAATGCTGTTAGTTGTTATTCGGCGATTTGCAACTGTTCCAGAACCAGAGTTTCCAGGTCATGTGATTCTGG
AACAGTATCAAGCCAATGTAGGAGCAGCGCTTAGACCAGCCTTCACTTCAGAGACACCACCTGATGTCACTGCCAAAGCATGTCAGGTTT
GCAGTGCCTGGATAGCAAGTGGAGTTGTAAGTGACCTTAATGATCTCCGAAGAGTTCATCAGTTGCTTGTTTCATCGTTAACTAAAATAC
AGGCTGGAAAAGAAGCTCTAAGTCACTTATATAATGAAAGTGCTTCTACCATGGAGATCTTAGCTGTGCTTAAAGCCTGGGCAGAGGTCT
ACATAATTGCTGTGCAAAGACATAAAAACCACAGACAACCTTTGAAGACTACCACCTGTTTAGAAGACGGTATCAGAAATGGATCATGTT
CATCAGATGGACTGCTTGACTTAGTCTATGCAGATCTTGGCACACTAAGCAGACTCTGGCTTGCTGCACTTCAGGATTTTGCTCTTTTAA
CTTTGCCTTCAGAATTTGCCTCCCAACTTCCTGCTGAAGGTGGTGCTTTCTACACAGCAGAGACTAGTGAAAATGCAAAATTGCATTATT
ACAACTCCTGGGCACTTATCCTCCATGCTACAGCATTGTGGCTTACAAGCACGGGTTTTGTTGTTGCTGACCCAGATGAAGGAGCATCTA
ATCTCTCCAGGCCTGTAACACCAACTTCCATGTGTCAGGGTTCATCATCTGGGGCTACCATAAAGTCCCCTGAGGATGTCTACACTGATA
GATTCCATCTTATTTTAGGAATCAGCGTGGAATTTCTATGTTCCTTACGTTCAGATGCAACCATGGAAAGCATAACTGCTTGTTTACATG
CATTGCAAGCACTTCTAGATGTACCTTGGCCCAGATCAAAAATTGGCAGTGATCAGGACTTGGGTATAGAATTGCTGAATGTTCTACATC
GAGTAATTTTAACCAGAGAATCACCTTCCATTCAGTTGGCTTCACTTGAAGTGGTAAGGCAGATTATCTGTGCTGCTCAAGAACATGTGA
AGGAAAAAAGACGAAGTGCAGAAGTTGATGATGGGGCTGCTGAAAAGGAAACTCTGCCAGAGTTTGGAGAGGGAAAGGACACCGGAGGAC
TTGTGCCTGGAAAGTCTTTGGTCTTTGCAACACTGGAATTGTGTGTATGCATTCTAGTTAGACAGCTCCCAGAATTAAACCCTAAATTGA
CAGGTAGCCCAGGAGTAAAAGCTACGAAGCCACAGATACTATTAGAAGATGGAAGTAGATTGGTTTCAGCTGCATTGGTTATCCTTTCCG
AACTTCCTGCAGTGTGCTCTCCTGAAGGAAGCATCTCAATTCTCCCTACTATATTGTACCTCACAATCGGGGTCCTCAGAGAGACTGCTG
TGAAGTTACCTGGGGGCCAGTTATCTTCGACAGTTGCAGCTTCCCTACAGGCTCTAAAAGGAATATTATCTTCTCCCATGGCCCGGGCAG
AAAAGAGCCGTACTGCTTGGACTGACCTTCTCCGAAGTGCCTTAACAACAATTCTTGACTGTTGGGATCCAGGGAAAGCAGCTAAAGAAG
CAGAAGCTAATCTTAGACGGCAGAGACGTCTAGTACGTTCCCAGGTTCTGAAATACATGGTTCCAGGAGCTCGTGTTATCAGAGGCCTGG
ATTGGAAATGGCGAGATCAGGATGGCAGCCCACAGGGAGAAGGCACTGTCACAGGAGAACTACACAATGGCTGGATTGATGTCACCTGGG
ATGCTGGTGGCTCAAACTCTTACCGTATGGGCGCAGAAGGAAAATTTGACCTCAAGCTTGCACCAGGGTACGACCCTGATACAGTGGCAT
CACCCAAACCTGTTTCATCCACTGTTTCAGGCACAACGCAATCATGGAGCAGCTTGGTGAAAAACAACTGTCCAGACAAGACATCTGCTG
CTGCAGGCTCCTCAAGTAGAAAAGGAAGCAGCAGTTCTGTGTGTAGCGTGGCCAGTAGCAGCGACATCAGCTTGGGTTCGACCAAAACGG
AACGGAGATCAGAAATTGTAATGGAACACAGTATAGTTTCAGGAGCTGATGTCCATGAACCAATTGTTGTTCTTTCATCTGCTGAAAACG
TCCCTCAAACAGAAGTAGGGTCATCTTCCAGTGCAAGCACCAGCACCTTAACAGCGGAAACGGGAAGTGAAAATGCTGAAAGGAAGTTAG
GCCCTGATAGTTCTGTTCGTACTCCTGGGGAGTCTAGTGCAATATCCATGGGAATTGTCAGTGTTAGTTCTCCTGATGTTAGTTCAGTAT
CTGAATTAACTAATAAAGAAGCAGCTTCACAACGACCTCTTAGCTCTTCAGCAAGTAACAGACTGTCAGTGAGTTCTTTGTTGGCTGCTG
GGGCCCCTATGAGCTCTAGTGCAAGTGTACCTAACCTGTCCTCAAGAGAAACATCTAGCTTGGAGAGTTTTGTAAGGAGAGTGGCAAACA
TAGCACGGACTAATGCCACGAACAACATGAATCTAAGCCGAAGCAGCAGTGATAACAACACTAATACTTTGGGGAGGAATGTGATGAGCA
CAGCAACTTCTCCTCTTATGGGTGCTCAGAGTTTCCCTAATTTGACCACACCTGGTACTACATCAACAGTGACTATGTCAACATCCAGTG
TTACTAGCAGCAGCAATGTAGCTACAGCAACAACAGTTTTATCAGTTGGTCAATCTTTAAGTAACACTTTAACCACCAGCCTCACATCAA
CTTCCAGTGAGAGTGACACAGGTCAGGAAGCAGAATATTCCTTATATGATTTCCTTGATAGCTGCCGTGCCAGTACTCTATTGGCTGAGC
TCGATGATGATGAGGACTTACCTGAGCCAGATGAAGAAGATGATGAGAATGAAGATGACAATCAGGAGGACCAAGAATACGAGGAGGTTA
TGATTCTGAGACGCCCATCCCTGCAACGTCGAGCTGGCTCCCGCTCTGATGTAACGCATCATGCTGTTACCTCGCAGCTACCACAGGTAC
CTGCTGGAGCAGGGAGCCGACCTATTGGGGAGCAGGAAGAAGAAGAGTACGAAACTAAAGGAGGACGCCGGAGAACATGGGATGATGATT
ATGTGCTAAAGAGACAGTTTTCTGCATTGGTTCCTGCTTTTGATCCTAGACCTGGTCGTACTAATGTCCAGCAGACAACTGATCTAGAAA
TACCACCCCCAGGGACCCCTCATTCAGAGCTCTTGGAAGAAGTCGAATGTACTCCGTCACCTCGATTAGCTCTCACTTTGAAAGTAACAG
GTCTTGGAACGACTCGTGAAGTTGAATTACCACTCACCAATTTCAGATCAACCATCTTTTACTATGTACAAAAATTGCTTCAATTGTCCT
GTAATGGCAATGTGAAATCAGATAAACTTAGGCGTATTTGGGAGCCCACATACACAATCATGTACAGAGAAATGAAGGATTCTGATAAAG
AAAAGGAAAATGGAAAAATGGGTTGCTGGTCTATAGAGCATGTGGAGCAGTACCTTGGCACTGATGAATTACCAAAGAATGACTTGATAA
CCTACCTGCAGAAGAATGCAGACGCTGCTTTCCTGCGCCACTGGAAATTAACTGGCACTAATAAAAGTATTAGGAAAAACAGAAATTGTT
CTCAGCTCATAGCTGCATATAAGGATTTTTGTGAGCATGGAACAAAGTCTGGGTTAAACCAGGGGGCCATTTCTACTCTTCAAAGTAGTG
ATATTCTTAATTTAACAAAAGAACAACCTCAGGCCAAAGCAGGCAATGGACAGAACTCTTGTGGAGTAGAAGATGTCCTTCAGCTTCTGC
GTATTCTATATATAGTTGCAAGTGACCCTTATTCAAGAATATCCCAGGAAGATGGTGATGAACAGCTTCAGTTTACTTTTCCACCAGATG
AATTCACTAGCAAAAAAATTACAACAAAAATATTACAGCAGATTGAGGAACCATTGGCACTGGCAAGTGGGGCTCTGCCAGACTGGTGTG
AACAATTAACCAGCAAATGTCCTTTTCTAATACCATTTGAAACTAGACAGCTTTATTTCACATGTACAGCATTTGGCGCCTCAAGAGCAA
TAGTATGGTTACAGAACCGACGTGAAGCCACTGTGGAGCGAACGAGAACCACAAGCAGTGTTAGGCGAGATGACCCTGGAGAGTTTCGAG
TTGGTCGTCTCAAGCATGAAAGAGTAAAAGTTCCACGTGGCGAGTCACTGATGGAATGGGCTGAGAATGTCATGCAAATACATGCAGATC
GGAAATCAGTTCTTGAGGTTGAATTTTTAGGAGAAGAAGGAACTGGCTTGGGACCCACATTAGAGTTTTATGCTCTGGTGGCAGCAGAAT
TCCAGAGAACTGACTTGGGAGCTTGGCTTTGTGATGATAATTTTCCAGATGATGAATCTCGTCACGTTGATCTTGGAGGTGGATTGAAAC
CTCCTGGATATTATGTGCAGAGGTCATGTGGACTGTTCACAGCACCATTTCCACAGGATAGTGATGAGCTTGAAAGGATCACGAAACTGT
TTCATTTCCTTGGAATTTTCTTGGCCAAATGCATTCAAGACAATAGACTTGTGGACTTACCTATTTCTAAACCTTTTTTTAAACTTATGT
GTATGGGTGACATTAAAAGCAATATGAGTAAACTGATTTATGAGTCACGAGGTGATAGAGACTTACACTGTACTGAAAGTCAGTCTGAAG
CTTCTACAGAAGAAGGTCATGATTCACTCTCGGTAGGAAGCTTTGAAGAGGATTCAAAATCAGAATTTATTCTTGATCCCCCTAAACCAA
AACCCCCAGCTTGGTTTAATGGAATTTTGACTTGGGAAGACTTTGAATTAGTAAACCCACACAGAGCCAGATTTTTAAAAGAAATTAAAG
ACCTTGCTATCAAGAGGCGCCAAATTTTAAGCAACAAAGGTCTTTCTGAAGATGAGAAGAACACAAAATTACAGGAACTAGTGCTGAAGA
ATCCATCAGGTTCTGGGCCTCCACTTAGCATAGAGGATTTAGGTTTAAATTTCCAGTTTTGCCCTTCCTCAAGAATATATGGTTTTACAG
CTGTGGATCTCAAGCCAAGTGGTGAAGATGAGATGATAACAATGGATAATGCAGAAGAATATGTGGATTTGATGTTTGACTTTTGTATGC
ATACGGGTATTCAGAAACAAATGGAAGCCTTTAGAGATGGGTTTAATAAAGTTTTTCCAATGGAGAAATTAAGTTCCTTCAGCCATGAAG
AAGTCCAAATGATTCTTTGTGGAAACCAGTCACCATCCTGGGCAGCAGAGGATATTATCAATTACACTGAACCTAAGCTGGGTTATACAC
GTGACAGCCCTGGTTTCCTGAGGTTTGTGAGGGTTTTATGTGGCATGTCTTCTGATGAAAGGAAAGCATTCTTGCAGTTTACCACTGGTT
GTTCAACTCTACCCCCAGGTGGACTGGCTAACCTGCATCCCAGGCTCACGGTTGTACGCAAGGTTGATGCTACTGATGCAAGCTATCCAT
CAGTCAATACATGTGTGCATTACCTTAAGTTGCCTGAATATTCTTCCGAGGAGATCATGAGAGAGCGCCTGCTAGCTGCTACAATGGAGA
AAGGCTTTCATCTCAATTGAGCTTTGAAGTGCAATGGGAGACATCAGAGACTTTAAAAATACTAGTGAAGCCTCTTGTGTTTGTGTGCAG
AGAAGTATATGATCCACCATGCTAATGACACTTGCCTTTTTTTCCACCATTAAGGCTTTAAGAACATGTGGAATAAGTTTTTTAGCTGCT
AATGACAAAACAAATCCTGTAACTACCCAGCCAGCAAGTATATAGCACAGAACACTGTGTTACTTTACAAGGGCTTATGTGACTGGAATA
AGGTGGTCCCACTTGACTGTTCCAAAGAGCAGCTTCTCAGATCTTCAGTGTTCACTGGTAAATTTCTAACAGTGTATTTGTGTAAAGTTT
GTCATTTCATACTCCATACACTACAGTTGCTGTCACTGATCCCTGTTTTGCTGGCTTTTAAGCTACTTGGTCAAAAATCCTGCTTCCTTA
AAACATAGAGAATTAATGAGCATCTCAAGCTTTTTCTTTTCCTTTTTAATGATGCCTGCACTATCAAGAGTATTCTAGTGTTCTCTCTTT
GTTTGGCATATAATCATGCACCAAACTTTTTATTTCTTTAAGGTGGGAGTATATTTTTATTTCCTAAATGCCATACTATGAAGATCAAAG
TCTTAAGTGTGTTTGCAGCTCAAAAATAAAGATGTATTAAGGGGGGAAAACCTGGTCTAAGTGCAAGGCACACTTACAGCGAGTTTTACT
TTCGGTTGTATTTTCTTTGTATATTATAAACATTTATTTAACTTGTTGCCGTTTGAAGTAAAAAATTTCCAAAATGTATGCTCAACAATA

>35963_35963_3_HEATR5A-HECTD1_HEATR5A_chr14_31771501_ENST00000439727_HECTD1_chr14_31602620_ENST00000399332_length(amino acids)=2915AA_BP=0
LEEVLELLGTGFLRGSSGFLRASGDMLKGTSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNFAAFFSHILSLASPSHPKATQTQIDAVCCR
RCVSFILRTTIGGLLGEKAQLAAVKDICQAIWKLKKVMDAVMSDGNLETRLGSTDVAASQHMLVCALQELGNLIHNLGTTAAPLLQDSST
GLLDSILSVILHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLTGHKSSPEAVTGFSFAVAALLGAVKHCPLGIPHGKGKIIMTLA
EDLLCSAAQNSRLSAQRTQAGWLLISALMTLGPAVVSHHLARVLLLWKCVFPASPKDLETEKSRGDSFTWQVTLEGRAGALCAIKSFVSH
CGDLLTEEVTQRLLPPLPCAVDLLTQLSSILKMYGSPLKTPSVVYRQRLYELLILLPPETYEGNLCAILRELAADLTAPDIQVAASTFLL
PPLCHQDDLLILSPFLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPALSVISSASKLFGVVCAHVGETQRLLIL
EQLLDSIKHTKGARQQVVQLHVVSSVSSFLKYVAGSKGCLGPEEMKRFALTLVMGALESPNPLLRCAAAESWARLAQVVDDGAFTAGLAQ
VSFDKLKSARDVVTRTGHSLALGSLHRYLGGISSSQHLNSCIGILYTLAQDSTSPDVQTWALHSLSLIIDSAGPLYYVHVEPTLSLIIML
LLNVPPTHAEVHQSLGRCLNALITTLGPELQGNSTSISTLRTSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVN
LCSPYLLLRRAVLACLRQLVQREAAEVSEHAVMLAKDSREELTPDANIREVGLEGALLILLDKETDERLCHDIKETLNYMLTSMAVEKLS
LWLKLCKDVLAASADFTAVTCVDTMQEEEGDKGDDASVLTTRRDEKSHPFTNPRWATRVFAAECVCRIINQCENANSAHFDIALAQEMKK
RDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLEMLLVVIRRFATVPEPEFPGHVILEQYQANVGAALRPAFTSETPPDVTAKACQVC
SAWIASGVVSDLNDLRRVHQLLVSSLTKIQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKNHRQPLKTTTCLEDGIRNGSCS
SDGLLDLVYADLGTLSRLWLAALQDFALLTLPSEFASQLPAEGGAFYTAETSENAKLHYYNSWALILHATALWLTSTGFVVADPDEGASN
LSRPVTPTSMCQGSSSGATIKSPEDVYTDRFHLILGISVEFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELLNVLHR
VILTRESPSIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLT
GSPGVKATKPQILLEDGSRLVSAALVILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQALKGILSSPMARAE
KSRTAWTDLLRSALTTILDCWDPGKAAKEAEANLRRQRRLVRSQVLKYMVPGARVIRGLDWKWRDQDGSPQGEGTVTGELHNGWIDVTWD
AGGSNSYRMGAEGKFDLKLAPGYDPDTVASPKPVSSTVSGTTQSWSSLVKNNCPDKTSAAAGSSSRKGSSSSVCSVASSSDISLGSTKTE
RRSEIVMEHSIVSGADVHEPIVVLSSAENVPQTEVGSSSSASTSTLTAETGSENAERKLGPDSSVRTPGESSAISMGIVSVSSPDVSSVS
ELTNKEAASQRPLSSSASNRLSVSSLLAAGAPMSSSASVPNLSSRETSSLESFVRRVANIARTNATNNMNLSRSSSDNNTNTLGRNVMST
ATSPLMGAQSFPNLTTPGTTSTVTMSTSSVTSSSNVATATTVLSVGQSLSNTLTTSLTSTSSESDTGQEAEYSLYDFLDSCRASTLLAEL
DDDEDLPEPDEEDDENEDDNQEDQEYEEVMILRRPSLQRRAGSRSDVTHHAVTSQLPQVPAGAGSRPIGEQEEEEYETKGGRRRTWDDDY
VLKRQFSALVPAFDPRPGRTNVQQTTDLEIPPPGTPHSELLEEVECTPSPRLALTLKVTGLGTTREVELPLTNFRSTIFYYVQKLLQLSC
NGNVKSDKLRRIWEPTYTIMYREMKDSDKEKENGKMGCWSIEHVEQYLGTDELPKNDLITYLQKNADAAFLRHWKLTGTNKSIRKNRNCS
QLIAAYKDFCEHGTKSGLNQGAISTLQSSDILNLTKEQPQAKAGNGQNSCGVEDVLQLLRILYIVASDPYSRISQEDGDEQLQFTFPPDE
FTSKKITTKILQQIEEPLALASGALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDDPGEFRV
GRLKHERVKVPRGESLMEWAENVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGAWLCDDNFPDDESRHVDLGGGLKP
PGYYVQRSCGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEA
STEEGHDSLSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIKDLAIKRRQILSNKGLSEDEKNTKLQELVLKN
PSGSGPPLSIEDLGLNFQFCPSSRIYGFTAVDLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEE
VQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPS

--------------------------------------------------------------
>35963_35963_4_HEATR5A-HECTD1_HEATR5A_chr14_31771501_ENST00000439727_HECTD1_chr14_31602620_ENST00000553700_length(transcript)=9562nt_BP=4662nt
CTTTGGAGGAAGTTCTGGAATTACTAGGAACAGGGTTTCTACGTGGGAGTTCAGGATTCCTTCGAGCCAGTGGAGATATGCTGAAAGGAA
CCAGTTCAGTCAGTAGGGATGTTCGAGTTGGAGTTACTCAGGCTTATGTGGTATTTGTTTCAACACTAGGAGGAGCTTGGCTAGAGAAAA
ATTTTGCTGCCTTTTTTTCTCATATCCTAAGCCTTGCGTCACCGTCACACCCTAAAGCCACCCAAACTCAGATCGATGCCGTCTGCTGTC
GCCGTTGTGTTTCATTTATTCTTCGAACTACTATAGGTGGTCTTCTTGGAGAAAAGGCTCAGCTTGCTGCTGTAAAGGATATTTGCCAGG
CCATCTGGAAGCTAAAGAAAGTTATGGATGCCGTAATGAGTGATGGTAATTTGGAAACCCGGCTTGGTTCCACAGATGTAGCCGCTAGCC
AACATATGCTGGTTTGTGCTTTACAAGAACTTGGAAATCTCATACACAATCTTGGCACCACAGCGGCACCTTTGCTACAGGATTCAAGTA
CAGGTCTCCTTGACAGTATCTTGTCAGTTATTCTTCATCCTAGCATTTCTGTTCGACTAGCAGCAGCTTGGTGTTTACACTGCATTGCCG
TGGCATTACCCTCCTACCTAACACCACTCTTGGATCGTTGCCTTGAACGGCTTACTGGACATAAGTCTTCACCTGAAGCAGTGACTGGCT
TCAGTTTTGCTGTAGCAGCTTTGTTGGGAGCAGTAAAACATTGTCCTTTAGGAATTCCTCATGGAAAAGGCAAGATTATTATGACATTAG
CAGAGGATTTGCTGTGTTCTGCTGCTCAAAACAGTCGCCTTTCAGCTCAGCGCACACAAGCTGGATGGTTGCTGATTTCTGCTCTGATGA
CATTAGGTCCTGCAGTTGTTAGCCATCACCTTGCTCGAGTTCTGCTGTTGTGGAAGTGTGTCTTTCCAGCATCTCCTAAAGATCTAGAAA
CAGAAAAGAGCCGAGGAGATTCGTTTACATGGCAGGTGACCCTGGAAGGACGAGCTGGTGCACTGTGTGCTATCAAGAGCTTTGTTTCCC
ACTGTGGTGATCTTCTTACTGAGGAAGTAACTCAGCGTCTTCTTCCACCACTTCCTTGTGCTGTGGATTTGCTAACTCAGCTTTCTTCAA
TACTAAAAATGTATGGAAGTCCTTTGAAAACACCGTCAGTGGTTTATAGACAAAGACTTTATGAACTGTTGATTTTATTACCTCCTGAGA
CCTATGAAGGAAACCTCTGTGCTATCCTCAGAGAGCTGGCTGCTGACTTGACTGCCCCTGATATTCAGGTGGCAGCATCTACATTTTTAC
TTCCACCCCTCTGTCATCAGGATGATCTTTTGATACTAAGTCCTTTCCTACAAGAGACTGACCATAGATTTATTGAAGAACAGCTCCTGC
TTGGTAATGGTGTTGCTTGCGGAAGTCTTGAATATGACCCTTATTCGATTTATGAGAAAGATGTAGAGGGAGATTCAGTGCCTAAGCCCT
TACCTCCAGCACTATCAGTTATTAGTTCTGCATCCAAGCTCTTTGGGGTTGTATGCGCTCATGTGGGAGAAACTCAAAGGCTTCTTATAT
TGGAACAGCTTTTGGACAGTATAAAGCACACAAAAGGAGCTCGTCAGCAAGTGGTTCAGTTACATGTTGTTTCTTCAGTTTCTAGTTTCT
TGAAGTACGTGGCTGGCTCCAAGGGATGTTTAGGTCCAGAAGAAATGAAAAGATTTGCCTTAACATTAGTTATGGGAGCCCTAGAAAGCC
CCAACCCCTTGCTGAGATGTGCAGCTGCAGAGTCATGGGCTAGATTAGCCCAAGTGGTAGATGATGGAGCTTTTACTGCTGGATTAGCTC
AAGTTAGCTTTGACAAATTGAAATCAGCAAGGGATGTGGTTACCAGAACAGGACACTCATTGGCCTTGGGGTCCCTACATAGGTATTTAG
GAGGAATAAGTTCTTCTCAACACCTAAATTCTTGTATTGGAATCCTTTATACTTTGGCGCAGGACAGCACTTCTCCTGATGTGCAGACCT
GGGCATTACATTCTCTATCATTGATCATTGATTCTGCTGGCCCACTCTATTATGTGCATGTGGAACCTACCCTTTCTCTTATTATAATGT
TGTTGTTAAATGTGCCTCCTACTCATGCTGAAGTTCACCAAAGCCTTGGTCGCTGTTTGAATGCCCTTATTACCACGTTAGGTCCAGAGC
TACAAGGTAACAGTACTTCAATTTCTACCTTAAGGACTTCCTGTCTACTGGGTTGTGCAGTAATGCAAGATAACCCAGACTGCCTTGTTC
AAGCTCAGGCCATCTCTTGCCTTCAGCAGCTTCATATGTTTGCTCCACGACATGTCAACTTGTCTAGCCTGGTTAGCTGCCTCTGTGTGA
ATCTTTGTAGCCCCTACTTGTTACTGAGAAGAGCAGTACTGGCTTGCTTACGTCAGCTTGTACAAAGAGAAGCAGCTGAAGTTTCAGAAC
ATGCTGTTATGCTTGCTAAGGATAGCAGAGAAGAGTTGACTCCAGATGCTAACATCAGAGAAGTTGGCCTTGAGGGGGCATTGTTGATCT
TACTAGACAAGGAGACAGATGAGAGATTATGCCATGATATCAAAGAGACTTTAAATTATATGCTTACATCTATGGCAGTGGAAAAACTCT
CCCTGTGGTTAAAGCTTTGTAAAGATGTACTTGCTGCATCAGCTGATTTTACAGCTGTAACTTGTGTGGATACAATGCAAGAAGAAGAAG
GAGATAAAGGGGATGATGCCTCAGTCCTGACCACCAGACGTGATGAAAAATCCCATCCTTTTACCAATCCCCGATGGGCTACTAGAGTCT
TTGCTGCTGAATGTGTCTGTAGGATAATTAACCAATGTGAGAATGCTAACAGTGCACATTTTGACATTGCTTTAGCACAAGAAATGAAAA
AAAGAGATTCAAGAAATGACTTTTTGGTACTGCATCTTGCTGACTTAATTCGCATGGCTTTTATGGCTGCCACAGATCACAGTGACCAGC
TCCGTCTTTCTGGCCTTGAAATGCTGTTAGTTGTTATTCGGCGATTTGCAACTGTTCCAGAACCAGAGTTTCCAGGTCATGTGATTCTGG
AACAGTATCAAGCCAATGTAGGAGCAGCGCTTAGACCAGCCTTCACTTCAGAGACACCACCTGATGTCACTGCCAAAGCATGTCAGGTTT
GCAGTGCCTGGATAGCAAGTGGAGTTGTAAGTGACCTTAATGATCTCCGAAGAGTTCATCAGTTGCTTGTTTCATCGTTAACTAAAATAC
AGGCTGGAAAAGAAGCTCTAAGTCACTTATATAATGAAAGTGCTTCTACCATGGAGATCTTAGCTGTGCTTAAAGCCTGGGCAGAGGTCT
ACATAATTGCTGTGCAAAGACATAAAAACCACAGACAACCTTTGAAGACTACCACCTGTTTAGAAGACGGTATCAGAAATGGATCATGTT
CATCAGATGGACTGCTTGACTTAGTCTATGCAGATCTTGGCACACTAAGCAGACTCTGGCTTGCTGCACTTCAGGATTTTGCTCTTTTAA
CTTTGCCTTCAGAATTTGCCTCCCAACTTCCTGCTGAAGGTGGTGCTTTCTACACAGCAGAGACTAGTGAAAATGCAAAATTGCATTATT
ACAACTCCTGGGCACTTATCCTCCATGCTACAGCATTGTGGCTTACAAGCACGGGTTTTGTTGTTGCTGACCCAGATGAAGGAGCATCTA
ATCTCTCCAGGCCTGTAACACCAACTTCCATGTGTCAGGGTTCATCATCTGGGGCTACCATAAAGTCCCCTGAGGATGTCTACACTGATA
GATTCCATCTTATTTTAGGAATCAGCGTGGAATTTCTATGTTCCTTACGTTCAGATGCAACCATGGAAAGCATAACTGCTTGTTTACATG
CATTGCAAGCACTTCTAGATGTACCTTGGCCCAGATCAAAAATTGGCAGTGATCAGGACTTGGGTATAGAATTGCTGAATGTTCTACATC
GAGTAATTTTAACCAGAGAATCACCTTCCATTCAGTTGGCTTCACTTGAAGTGGTAAGGCAGATTATCTGTGCTGCTCAAGAACATGTGA
AGGAAAAAAGACGAAGTGCAGAAGTTGATGATGGGGCTGCTGAAAAGGAAACTCTGCCAGAGTTTGGAGAGGGAAAGGACACCGGAGGAC
TTGTGCCTGGAAAGTCTTTGGTCTTTGCAACACTGGAATTGTGTGTATGCATTCTAGTTAGACAGCTCCCAGAATTAAACCCTAAATTGA
CAGGTAGCCCAGGAGTAAAAGCTACGAAGCCACAGATACTATTAGAAGATGGAAGTAGATTGGTTTCAGCTGCATTGGTTATCCTTTCCG
AACTTCCTGCAGTGTGCTCTCCTGAAGGAAGCATCTCAATTCTCCCTACTATATTGTACCTCACAATCGGGGTCCTCAGAGAGACTGCTG
TGAAGTTACCTGGGGGCCAGTTATCTTCGACAGTTGCAGCTTCCCTACAGGCTCTAAAAGGAATATTATCTTCTCCCATGGCCCGGGCAG
AAAAGAGCCGTACTGCTTGGACTGACCTTCTCCGAAGTGCCTTAACAACAATTCTTGACTGTTGGGATCCAGGGAAAGCAGCTAAAGAAG
CAGAAGCTAATCTTAGACGGCAGAGACGTCTAGTACGTTCCCAGGTTCTGAAATACATGGTTCCAGGAGCTCGTGTTATCAGAGGCCTGG
ATTGGAAATGGCGAGATCAGGATGGCAGCCCACAGGGAGAAGGCACTGTCACAGGAGAACTACACAATGGCTGGATTGATGTCACCTGGG
ATGCTGGTGGCTCAAACTCTTACCGTATGGGCGCAGAAGGAAAATTTGACCTCAAGCTTGCACCAGGGTACGACCCTGATACAGTGGCAT
CACCCAAACCTGTTTCATCCACTGTTTCAGGCACAACGCAATCATGGAGCAGCTTGGTGAAAAACAACTGTCCAGACAAGACATCTGCTG
CTGCAGGCTCCTCAAGTAGAAAAGGAAGCAGCAGTTCTGTGTGTAGCGTGGCCAGTAGCAGCGACATCAGCTTGGGTTCGACCAAAACGG
AACGGAGATCAGAAATTGTAATGGAACACAGTATAGTTTCAGGAGCTGATGTCCATGAACCAATTGTTGTTCTTTCATCTGCTGAAAACG
TCCCTCAAACAGAAGTAGGGTCATCTTCCAGTGCAAGCACCAGCACCTTAACAGCGGAAACGGGAAGTGAAAATGCTGAAAGGAAGTTAG
GCCCTGATAGTTCTGTTCGTACTCCTGGGGAGTCTAGTGCAATATCCATGGGAATTGTCAGTGTTAGTTCTCCTGATGTTAGTTCAGTAT
CTGAATTAACTAATAAAGAAGCAGCTTCACAACGACCTCTTAGCTCTTCAGCAAGTAACAGACTGTCAGTGAGTTCTTTGTTGGCTGCTG
GGGCCCCTATGAGCTCTAGTGCAAGTGTACCTAACCTGTCCTCAAGAGAAACATCTAGCTTGGAGAGTTTTGTAAGGAGAGTGGCAAACA
TAGCACGGACTAATGCCACGAACAACATGAATCTAAGCCGAAGCAGCAGTGATAACAACACTAATACTTTGGGGAGGAATGTGATGAGCA
CAGCAACTTCTCCTCTTATGGGTGCTCAGAGTTTCCCTAATTTGACCACACCTGGTACTACATCAACAGTGACTATGTCAACATCCAGTG
TTACTAGCAGCAGCAATGTAGCTACAGCAACAACAGTTTTATCAGTTGGTCAATCTTTAAGTAACACTTTAACCACCAGCCTCACATCAA
CTTCCAGTGAGAGTGACACAGGTCAGGAAGCAGAATATTCCTTATATGATTTCCTTGATAGCTGCCGTGCCAGTACTCTATTGGCTGAGC
TCGATGATGATGAGGACTTACCTGAGCCAGATGAAGAAGATGATGAGAATGAAGATGACAATCAGGAGGACCAAGAATACGAGGAGGTTA
TGATTCTGAGACGCCCATCCCTGCAACGTCGAGCTGGCTCCCGCTCTGATGTAACGCATCATGCTGTTACCTCGCAGCTACCACAGGTAC
CTGCTGGAGCAGGGAGCCGACCTATTGGGGAGCAGGAAGAAGAAGAGTACGAAACTAAAGGAGGACGCCGGAGAACATGGGATGATGATT
ATGTGCTAAAGAGACAGTTTTCTGCATTGGTTCCTGCTTTTGATCCTAGACCTGGTCGTACTAATGTCCAGCAGACAACTGATCTAGAAA
TACCACCCCCAGGGACCCCTCATTCAGAGCTCTTGGAAGAAGTCGAATGTACTCCGTCACCTCGATTAGCTCTCACTTTGAAAGTAACAG
GTCTTGGAACGACTCGTGAAGTTGAATTACCACTCACCAATTTCAGATCAACCATCTTTTACTATGTACAAAAATTGCTTCAATTGTCCT
GTAATGGCAATGTGAAATCAGATAAACTTAGGCGTATTTGGGAGCCCACATACACAATCATGTACAGAGAAATGAAGGATTCTGATAAAG
AAAAGGAAAATGGAAAAATGGGTTGCTGGTCTATAGAGCATGTGGAGCAGTACCTTGGCACTGATGAATTACCAAAGAATGACTTGATAA
CCTACCTGCAGAAGAATGCAGACGCTGCTTTCCTGCGCCACTGGAAATTAACTGGCACTAATAAAAGTATTAGGAAAAACAGAAATTGTT
CTCAGCTCATAGCTGCATATAAGGATTTTTGTGAGCATGGAACAAAGTCTGGGTTAAACCAGGGGGCCATTTCTACTCTTCAAAGTAGTG
ATATTCTTAATTTAACAAAAGAACAACCTCAGGCCAAAGCAGGCAATGGACAGAACTCTTGTGGAGTAGAAGATGTCCTTCAGCTTCTGC
GTATTCTATATATAGTTGCAAGTGACCCTTATTCAAGAATATCCCAGGAAGATGGTGATGAACAGCTTCAGTTTACTTTTCCACCAGATG
AATTCACTAGCAAAAAAATTACAACAAAAATATTACAGCAGATTGAGGAACCATTGGCACTGGCAAGTGGGGCTCTGCCAGACTGGTGTG
AACAATTAACCAGCAAATGTCCTTTTCTAATACCATTTGAAACTAGACAGCTTTATTTCACATGTACAGCATTTGGCGCCTCAAGAGCAA
TAGTATGGTTACAGAACCGACGTGAAGCCACTGTGGAGCGAACGAGAACCACAAGCAGTGTTAGGCGAGATGACCCTGGAGAGTTTCGAG
TTGGTCGTCTCAAGCATGAAAGAGTAAAAGTTCCACGTGGCGAGTCACTGATGGAATGGGCTGAGAATGTCATGCAAATACATGCAGATC
GGAAATCAGTTCTTGAGGTTGAATTTTTAGGAGAAGAAGGAACTGGCTTGGGACCCACATTAGAGTTTTATGCTCTGGTGGCAGCAGAAT
TCCAGAGAACTGACTTGGGAGCTTGGCTTTGTGATGATAATTTTCCAGATGATGAATCTCGTCACGTTGATCTTGGAGGTGGATTGAAAC
CTCCTGGATATTATGTGCAGAGGTCATGTGGACTGTTCACAGCACCATTTCCACAGGATAGTGATGAGCTTGAAAGGATCACGAAACTGT
TTCATTTCCTTGGAATTTTCTTGGCCAAATGCATTCAAGACAATAGACTTGTGGACTTACCTATTTCTAAACCTTTTTTTAAACTTATGT
GTATGGGTGACATTAAAAGCAATATGAGTAAACTGATTTATGAGTCACGAGGTGATAGAGACTTACACTGTACTGAAAGTCAGTCTGAAG
CTTCTACAGAAGAAGGTCATGATTCACTCTCGGTAGGAAGCTTTGAAGAGGATTCAAAATCAGAATTTATTCTTGATCCCCCTAAACCAA
AACCCCCAGCTTGGTTTAATGGAATTTTGACTTGGGAAGACTTTGAATTAGTAAACCCACACAGAGCCAGATTTTTAAAAGAAATTAAAG
ACCTTGCTATCAAGAGGCGCCAAATTTTAAGCAACAAAGGTCTTTCTGAAGATGAGAAGAACACAAAATTACAGGAACTAGTGCTGAAGA
ATCCATCAGGTTCTGGGCCTCCACTTAGCATAGAGGATTTAGGTTTAAATTTCCAGTTTTGCCCTTCCTCAAGAATATATGGTTTTACAG
CTGTGGATCTCAAGCCAAGTGGTGAAGATGAGATGATAACAATGGATAATGCAGAAGAATATGTGGATTTGATGTTTGACTTTTGTATGC
ATACGGGTATTCAGAAACAAATGGAAGCCTTTAGAGATGGGTTTAATAAAGTTTTTCCAATGGAGAAATTAAGTTCCTTCAGCCATGAAG
AAGTCCAAATGATTCTTTGTGGAAACCAGTCACCATCCTGGGCAGCAGAGGATATTATCAATTACACTGAACCTAAGCTGGGTTATACAC
GTGACAGCCCTGGTTTCCTGAGGTTTGTGAGGGTTTTATGTGGCATGTCTTCTGATGAAAGGAAAGCATTCTTGCAGTTTACCACTGGTT
GTTCAACTCTACCCCCAGGTGGACTGGCTAACCTGCATCCCAGGCTCACGGTTGTACGCAAGGTTGATGCTACTGATGCAAGCTATCCAT
CAGTCAATACATGTGTGCATTACCTTAAGTTGCCTGAATATTCTTCCGAGGAGATCATGAGAGAGCGCCTGCTAGCTGCTACAATGGAGA
AAGGCTTTCATCTCAATTGAGCTTTGAAGTGCAATGGGAGACATCAGAGACTTTAAAAATACTAGTGAAGCCTCTTGTGTTTGTGTGCAG
AGAAGTATATGATCCACCATGCTAATGACACTTGCCTTTTTTTCCACCATTAAGGCTTTAAGAACATGTGGAATAAGTTTTTTAGCTGCT
AATGACAAAACAAATCCTGTAACTACCCAGCCAGCAAGTATATAGCACAGAACACTGTGTTACTTTACAAGGGCTTATGTGACTGGAATA
AGGTGGTCCCACTTGACTGTTCCAAAGAGCAGCTTCTCAGATCTTCAGTGTTCACTGGTAAATTTCTAACAGTGTATTTGTGTAAAGTTT
GTCATTTCATACTCCATACACTACAGTTGCTGTCACTGATCCCTGTTTTGCTGGCTTTTAAGCTACTTGGTCAAAAATCCTGCTTCCTTA
AAACATAGAGAATTAATGAGCATCTCAAGCTTTTTCTTTTCCTTTTTAATGATGCCTGCACTATCAAGAGTATTCTAGTGTTCTCTCTTT
GTTTGGCATATAATCATGCACCAAACTTTTTATTTCTTTAAGGTGGGAGTATATTTTTATTTCCTAAATGCCATACTATGAAGATCAAAG
TCTTAAGTGTGTTTGCAGCTCAAAAATAAAGATGTATTAAGGGGGGAAAACCTGGTCTAAGTGCAAGGCACACTTACAGCGAGTTTTACT
TTCGGTTGTATTTTCTTTGTATATTATAAACATTTATTTAACTTGTTGCCGTTTGAAGTAAAAAATTTCCAAAATGTATGCTCAACAATA

>35963_35963_4_HEATR5A-HECTD1_HEATR5A_chr14_31771501_ENST00000439727_HECTD1_chr14_31602620_ENST00000553700_length(amino acids)=2915AA_BP=0
LEEVLELLGTGFLRGSSGFLRASGDMLKGTSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNFAAFFSHILSLASPSHPKATQTQIDAVCCR
RCVSFILRTTIGGLLGEKAQLAAVKDICQAIWKLKKVMDAVMSDGNLETRLGSTDVAASQHMLVCALQELGNLIHNLGTTAAPLLQDSST
GLLDSILSVILHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLTGHKSSPEAVTGFSFAVAALLGAVKHCPLGIPHGKGKIIMTLA
EDLLCSAAQNSRLSAQRTQAGWLLISALMTLGPAVVSHHLARVLLLWKCVFPASPKDLETEKSRGDSFTWQVTLEGRAGALCAIKSFVSH
CGDLLTEEVTQRLLPPLPCAVDLLTQLSSILKMYGSPLKTPSVVYRQRLYELLILLPPETYEGNLCAILRELAADLTAPDIQVAASTFLL
PPLCHQDDLLILSPFLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPALSVISSASKLFGVVCAHVGETQRLLIL
EQLLDSIKHTKGARQQVVQLHVVSSVSSFLKYVAGSKGCLGPEEMKRFALTLVMGALESPNPLLRCAAAESWARLAQVVDDGAFTAGLAQ
VSFDKLKSARDVVTRTGHSLALGSLHRYLGGISSSQHLNSCIGILYTLAQDSTSPDVQTWALHSLSLIIDSAGPLYYVHVEPTLSLIIML
LLNVPPTHAEVHQSLGRCLNALITTLGPELQGNSTSISTLRTSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVN
LCSPYLLLRRAVLACLRQLVQREAAEVSEHAVMLAKDSREELTPDANIREVGLEGALLILLDKETDERLCHDIKETLNYMLTSMAVEKLS
LWLKLCKDVLAASADFTAVTCVDTMQEEEGDKGDDASVLTTRRDEKSHPFTNPRWATRVFAAECVCRIINQCENANSAHFDIALAQEMKK
RDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLEMLLVVIRRFATVPEPEFPGHVILEQYQANVGAALRPAFTSETPPDVTAKACQVC
SAWIASGVVSDLNDLRRVHQLLVSSLTKIQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKNHRQPLKTTTCLEDGIRNGSCS
SDGLLDLVYADLGTLSRLWLAALQDFALLTLPSEFASQLPAEGGAFYTAETSENAKLHYYNSWALILHATALWLTSTGFVVADPDEGASN
LSRPVTPTSMCQGSSSGATIKSPEDVYTDRFHLILGISVEFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELLNVLHR
VILTRESPSIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLT
GSPGVKATKPQILLEDGSRLVSAALVILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQALKGILSSPMARAE
KSRTAWTDLLRSALTTILDCWDPGKAAKEAEANLRRQRRLVRSQVLKYMVPGARVIRGLDWKWRDQDGSPQGEGTVTGELHNGWIDVTWD
AGGSNSYRMGAEGKFDLKLAPGYDPDTVASPKPVSSTVSGTTQSWSSLVKNNCPDKTSAAAGSSSRKGSSSSVCSVASSSDISLGSTKTE
RRSEIVMEHSIVSGADVHEPIVVLSSAENVPQTEVGSSSSASTSTLTAETGSENAERKLGPDSSVRTPGESSAISMGIVSVSSPDVSSVS
ELTNKEAASQRPLSSSASNRLSVSSLLAAGAPMSSSASVPNLSSRETSSLESFVRRVANIARTNATNNMNLSRSSSDNNTNTLGRNVMST
ATSPLMGAQSFPNLTTPGTTSTVTMSTSSVTSSSNVATATTVLSVGQSLSNTLTTSLTSTSSESDTGQEAEYSLYDFLDSCRASTLLAEL
DDDEDLPEPDEEDDENEDDNQEDQEYEEVMILRRPSLQRRAGSRSDVTHHAVTSQLPQVPAGAGSRPIGEQEEEEYETKGGRRRTWDDDY
VLKRQFSALVPAFDPRPGRTNVQQTTDLEIPPPGTPHSELLEEVECTPSPRLALTLKVTGLGTTREVELPLTNFRSTIFYYVQKLLQLSC
NGNVKSDKLRRIWEPTYTIMYREMKDSDKEKENGKMGCWSIEHVEQYLGTDELPKNDLITYLQKNADAAFLRHWKLTGTNKSIRKNRNCS
QLIAAYKDFCEHGTKSGLNQGAISTLQSSDILNLTKEQPQAKAGNGQNSCGVEDVLQLLRILYIVASDPYSRISQEDGDEQLQFTFPPDE
FTSKKITTKILQQIEEPLALASGALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDDPGEFRV
GRLKHERVKVPRGESLMEWAENVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGAWLCDDNFPDDESRHVDLGGGLKP
PGYYVQRSCGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEA
STEEGHDSLSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIKDLAIKRRQILSNKGLSEDEKNTKLQELVLKN
PSGSGPPLSIEDLGLNFQFCPSSRIYGFTAVDLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEE
VQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPS

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Fusion Gene PPI Analysis for HEATR5A-HECTD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for HEATR5A-HECTD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for HEATR5A-HECTD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource