FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:HIVEP3-PRRG1 (FusionGDB2 ID:36563)

Fusion Gene Summary for HIVEP3-PRRG1

check button Fusion gene summary
Fusion gene informationFusion gene name: HIVEP3-PRRG1
Fusion gene ID: 36563
HgeneTgene
Gene symbol

HIVEP3

PRRG1

Gene ID

59269

5638

Gene nameHIVEP zinc finger 3proline rich and Gla domain 1
SynonymsKBP-1|KBP1|KRC|SHN3|Schnurri-3|ZAS3|ZNF40CPRGP1
Cytomap

1p34.2

Xp21.1

Type of geneprotein-codingprotein-coding
Descriptiontranscription factor HIVEP3ZAS family, member 3human immunodeficiency virus type I enhancer binding protein 3kappa-B and V(D)J recombination signal sequences-binding proteinkappa-binding protein 1zinc finger protein ZAS3transmembrane gamma-carboxyglutamic acid protein 1proline rich Gla (G-carboxyglutamic acid) 1proline-rich Gla (G-carboxyglutamic acid) polypeptide 1
Modification date2020031320200313
UniProtAcc

Q5T1R4

.
Ensembl transtripts involved in fusion geneENST00000247584, ENST00000372583, 
ENST00000372584, ENST00000429157, 
ENST00000460604, 		ENST00000449135, 
ENST00000491253, ENST00000542554, 
ENST00000543642, ENST00000463135, 
ENST00000378628, 
Fusion gene scores* DoF score21 X 18 X 10=37803 X 3 X 2=18
# samples 254
** MAII scorelog2(25/3780*10)=-3.91838623444635
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/18*10)=1.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: HIVEP3 [Title/Abstract] AND PRRG1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointHIVEP3(42041215)-PRRG1(37312389), # samples:1
Anticipated loss of major functional domain due to fusion event.HIVEP3-PRRG1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
HIVEP3-PRRG1 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneHIVEP3

GO:0045893

positive regulation of transcription, DNA-templated

15790681


check buttonFusion gene breakpoints across HIVEP3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PRRG1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CG-5724-01AHIVEP3chr1

42041215

-PRRG1chrX

37312389

+


Top

Fusion Gene ORF analysis for HIVEP3-PRRG1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000247584ENST00000449135HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000247584ENST00000491253HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000247584ENST00000542554HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000247584ENST00000543642HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000372583ENST00000449135HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000372583ENST00000491253HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000372583ENST00000542554HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000372583ENST00000543642HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000372584ENST00000449135HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000372584ENST00000491253HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000372584ENST00000542554HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000372584ENST00000543642HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000429157ENST00000449135HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000429157ENST00000491253HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000429157ENST00000542554HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-3UTRENST00000429157ENST00000543642HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-intronENST00000247584ENST00000463135HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-intronENST00000372583ENST00000463135HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-intronENST00000372584ENST00000463135HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5CDS-intronENST00000429157ENST00000463135HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5UTR-3CDSENST00000460604ENST00000378628HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5UTR-3UTRENST00000460604ENST00000449135HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5UTR-3UTRENST00000460604ENST00000491253HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5UTR-3UTRENST00000460604ENST00000542554HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5UTR-3UTRENST00000460604ENST00000543642HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
5UTR-intronENST00000460604ENST00000463135HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
Frame-shiftENST00000247584ENST00000378628HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
Frame-shiftENST00000372584ENST00000378628HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
Frame-shiftENST00000429157ENST00000378628HIVEP3chr1

42041215

-PRRG1chrX

37312389

+
In-frameENST00000372583ENST00000378628HIVEP3chr1

42041215

-PRRG1chrX

37312389

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000372583HIVEP3chr142041215-ENST00000378628PRRG1chrX37312389+10253609388661831765

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000372583ENST00000378628HIVEP3chr142041215-PRRG1chrX37312389+0.0013369090.99866307

Top

Fusion Genomic Features for HIVEP3-PRRG1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
HIVEP3chr142041214-PRRG1chrX37312388+0.254250850.7457491
HIVEP3chr142041214-PRRG1chrX37312388+0.254250850.7457491

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for HIVEP3-PRRG1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:42041215/chrX:37312389)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
HIVEP3

Q5T1R4

.
FUNCTION: Plays a role of transcription factor; binds to recognition signal sequences (Rss heptamer) for somatic recombination of immunoglobulin and T-cell receptor gene segments; Binds also to the kappa-B motif of gene such as S100A4, involved in cell progression and differentiation. Kappa-B motif is a gene regulatory element found in promoters and enhancers of genes involved in immunity, inflammation, and growth and that responds to viral antigens, mitogens, and cytokines. Involvement of HIVEP3 in cell growth is strengthened by the fact that its down-regulation promotes cell cycle progression with ultimate formation of multinucleated giant cells. Strongly inhibits TNF-alpha-induced NF-kappa-B activation; Interferes with nuclear factor NF-kappa-B by several mechanisms: as transcription factor, by competing for Kappa-B motif and by repressing transcription in the nucleus; through a non transcriptional process, by inhibiting nuclear translocation of RELA by association with TRAF2, an adapter molecule in the tumor necrosis factor signaling, which blocks the formation of IKK complex. Interaction with TRAF proteins inhibits both NF-Kappa-B-mediated and c-Jun N-terminal kinase/JNK-mediated responses that include apoptosis and proinflammatory cytokine gene expression. Positively regulates the expression of IL2 in T-cell. Essential regulator of adult bone formation. {ECO:0000269|PubMed:11161801}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-481442_146617352407.0Coiled coilOntology_term=ECO:0000255
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-591442_146617352407.0Coiled coilOntology_term=ECO:0000255
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-481442_146617352406.0Coiled coilOntology_term=ECO:0000255
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-481442_146617352406.0Coiled coilOntology_term=ECO:0000255
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-48308_33417352407.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-48378_41417352407.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-48797_81917352407.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-48844_88017352407.0Compositional biasNote=Glu/Pro-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-48916_94817352407.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-59308_33417352407.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-59378_41417352407.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-59797_81917352407.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-59844_88017352407.0Compositional biasNote=Glu/Pro-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-59916_94817352407.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-48308_33417352406.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-48378_41417352406.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-48797_81917352406.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-48844_88017352406.0Compositional biasNote=Glu/Pro-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-48916_94817352406.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-48308_33417352406.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-48378_41417352406.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-48797_81917352406.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-48844_88017352406.0Compositional biasNote=Glu/Pro-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-48916_94817352406.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-48903_90917352407.0MotifNuclear localization signal
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-59903_90917352407.0MotifNuclear localization signal
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-48903_90917352406.0MotifNuclear localization signal
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-48903_90917352406.0MotifNuclear localization signal
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-48192_24217352407.0RegionNote=ZAS1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-48211_107417352407.0RegionNo DNA binding activity or transactivation activity%2C but complete prevention of TRAF-dependent NF-Kappa-B activation%3B associates with TRAF2 and JUN
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-48264_28717352407.0RegionNote=Acidic 1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-48862_88317352407.0RegionNote=Acidic 2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-59192_24217352407.0RegionNote=ZAS1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-59211_107417352407.0RegionNo DNA binding activity or transactivation activity%2C but complete prevention of TRAF-dependent NF-Kappa-B activation%3B associates with TRAF2 and JUN
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-59264_28717352407.0RegionNote=Acidic 1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-59862_88317352407.0RegionNote=Acidic 2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-48192_24217352406.0RegionNote=ZAS1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-48211_107417352406.0RegionNo DNA binding activity or transactivation activity%2C but complete prevention of TRAF-dependent NF-Kappa-B activation%3B associates with TRAF2 and JUN
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-48264_28717352406.0RegionNote=Acidic 1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-48862_88317352406.0RegionNote=Acidic 2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-48192_24217352406.0RegionNote=ZAS1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-48211_107417352406.0RegionNo DNA binding activity or transactivation activity%2C but complete prevention of TRAF-dependent NF-Kappa-B activation%3B associates with TRAF2 and JUN
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-48264_28717352406.0RegionNote=Acidic 1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-48862_88317352406.0RegionNote=Acidic 2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-48192_21417352407.0Zinc fingerC2H2-type 1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-48220_24217352407.0Zinc fingerC2H2-type 2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-48640_67017352407.0Zinc fingerCCHC HIVEP-type
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-59192_21417352407.0Zinc fingerC2H2-type 1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-59220_24217352407.0Zinc fingerC2H2-type 2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-59640_67017352407.0Zinc fingerCCHC HIVEP-type
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-48192_21417352406.0Zinc fingerC2H2-type 1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-48220_24217352406.0Zinc fingerC2H2-type 2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-48640_67017352406.0Zinc fingerCCHC HIVEP-type
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-48192_21417352406.0Zinc fingerC2H2-type 1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-48220_24217352406.0Zinc fingerC2H2-type 2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-48640_67017352406.0Zinc fingerCCHC HIVEP-type
TgenePRRG1chr1:42041215chrX:37312389ENST0000037862824131_13557219.0Compositional biasNote=Poly-Pro
TgenePRRG1chr1:42041215chrX:37312389ENST0000044913535131_13557219.0Compositional biasNote=Poly-Pro
TgenePRRG1chr1:42041215chrX:37312389ENST0000046313504131_135083.0Compositional biasNote=Poly-Pro
TgenePRRG1chr1:42041215chrX:37312389ENST0000054255435131_13557219.0Compositional biasNote=Poly-Pro
TgenePRRG1chr1:42041215chrX:37312389ENST0000054364224131_13557219.0Compositional biasNote=Poly-Pro
TgenePRRG1chr1:42041215chrX:37312389ENST000004631350421_66083.0DomainGla
TgenePRRG1chr1:42041215chrX:37312389ENST0000037862824107_21857219.0Topological domainCytoplasmic
TgenePRRG1chr1:42041215chrX:37312389ENST0000044913535107_21857219.0Topological domainCytoplasmic
TgenePRRG1chr1:42041215chrX:37312389ENST0000046313504107_218083.0Topological domainCytoplasmic
TgenePRRG1chr1:42041215chrX:37312389ENST000004631350421_83083.0Topological domainExtracellular
TgenePRRG1chr1:42041215chrX:37312389ENST0000054255435107_21857219.0Topological domainCytoplasmic
TgenePRRG1chr1:42041215chrX:37312389ENST0000054364224107_21857219.0Topological domainCytoplasmic
TgenePRRG1chr1:42041215chrX:37312389ENST000003786282484_10657219.0TransmembraneHelical
TgenePRRG1chr1:42041215chrX:37312389ENST000004491353584_10657219.0TransmembraneHelical
TgenePRRG1chr1:42041215chrX:37312389ENST000004631350484_106083.0TransmembraneHelical
TgenePRRG1chr1:42041215chrX:37312389ENST000005425543584_10657219.0TransmembraneHelical
TgenePRRG1chr1:42041215chrX:37312389ENST000005436422484_10657219.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-481907_193617352407.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-591907_193617352407.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-481907_193617352406.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-481907_193617352406.0Compositional biasNote=Ser-rich
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-481754_180617352407.0RegionNote=ZAS2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-481817_187217352407.0RegionNote=Acidic 3
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-482053_214817352407.0RegionNote=6 X 4 AA tandem repeats of S-P-X-[RK]
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-591754_180617352407.0RegionNote=ZAS2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-591817_187217352407.0RegionNote=Acidic 3
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-592053_214817352407.0RegionNote=6 X 4 AA tandem repeats of S-P-X-[RK]
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-481754_180617352406.0RegionNote=ZAS2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-481817_187217352406.0RegionNote=Acidic 3
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-482053_214817352406.0RegionNote=6 X 4 AA tandem repeats of S-P-X-[RK]
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-481754_180617352406.0RegionNote=ZAS2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-481817_187217352406.0RegionNote=Acidic 3
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-482053_214817352406.0RegionNote=6 X 4 AA tandem repeats of S-P-X-[RK]
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-481964_196717352407.0RepeatNote=1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-481970_197317352407.0RepeatNote=2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-481993_199617352407.0RepeatNote=3
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-481998_200117352407.0RepeatNote=4
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-482067_207017352407.0RepeatNote=5
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-482079_208217352407.0RepeatNote=6
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-591964_196717352407.0RepeatNote=1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-591970_197317352407.0RepeatNote=2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-591993_199617352407.0RepeatNote=3
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-591998_200117352407.0RepeatNote=4
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-592067_207017352407.0RepeatNote=5
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-592079_208217352407.0RepeatNote=6
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-481964_196717352406.0RepeatNote=1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-481970_197317352406.0RepeatNote=2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-481993_199617352406.0RepeatNote=3
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-481998_200117352406.0RepeatNote=4
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-482067_207017352406.0RepeatNote=5
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-482079_208217352406.0RepeatNote=6
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-481964_196717352406.0RepeatNote=1
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-481970_197317352406.0RepeatNote=2
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-481993_199617352406.0RepeatNote=3
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-481998_200117352406.0RepeatNote=4
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-482067_207017352406.0RepeatNote=5
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-482079_208217352406.0RepeatNote=6
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-481754_177617352407.0Zinc fingerC2H2-type 3
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000247584-481782_180617352407.0Zinc fingerC2H2-type 4
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-591754_177617352407.0Zinc fingerC2H2-type 3
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372583-591782_180617352407.0Zinc fingerC2H2-type 4
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-481754_177617352406.0Zinc fingerC2H2-type 3
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000372584-481782_180617352406.0Zinc fingerC2H2-type 4
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-481754_177617352406.0Zinc fingerC2H2-type 3
HgeneHIVEP3chr1:42041215chrX:37312389ENST00000429157-481782_180617352406.0Zinc fingerC2H2-type 4
TgenePRRG1chr1:42041215chrX:37312389ENST000003786282421_6657219.0DomainGla
TgenePRRG1chr1:42041215chrX:37312389ENST000004491353521_6657219.0DomainGla
TgenePRRG1chr1:42041215chrX:37312389ENST000005425543521_6657219.0DomainGla
TgenePRRG1chr1:42041215chrX:37312389ENST000005436422421_6657219.0DomainGla
TgenePRRG1chr1:42041215chrX:37312389ENST000003786282421_8357219.0Topological domainExtracellular
TgenePRRG1chr1:42041215chrX:37312389ENST000004491353521_8357219.0Topological domainExtracellular
TgenePRRG1chr1:42041215chrX:37312389ENST000005425543521_8357219.0Topological domainExtracellular
TgenePRRG1chr1:42041215chrX:37312389ENST000005436422421_8357219.0Topological domainExtracellular


Top

Fusion Gene Sequence for HIVEP3-PRRG1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>36563_36563_1_HIVEP3-PRRG1_HIVEP3_chr1_42041215_ENST00000372583_PRRG1_chrX_37312389_ENST00000378628_length(transcript)=10253nt_BP=6093nt
CCTGCCTGGCCGGAATAATTCATGAAGAAGGGGCTGGATCCGTGGGTCAGAGAACACAGGACCAGTTTGCCATCCCAAGGCCGAAGGCCT
CCCTCCAACACAGTTCTCCAAGCTCTAGAAATCTCTGACACATCTTGACCATGAGACCACGGCTGGTTTTTGGCAGGATTCGAGGCACAA
ACCCAGCAGCCTCAACCTAGTTCATGGAGGAGCCTCGCGGGGTCCTGGCCAAGCAAGCCCGCCCCTCTGGTGGGAAGAGCGGCGCCTAGG
TGGAGGGTGGCTGCCGTAGGAGTGGACATGAATGCTGGCTTTCAGAGAGAACAGCGTTTCAGTTTTGGTCATCGGAAGTGGTGCCTTCAG
CACAGAAGAAGAGCGTGATTTCTCCTCCAAGGCCGTTGATCTCCAACCCAGAACTAAAGGGGAGAAGAGCCACCCCCAGCATCCAGCGTG
GCATCTCTTGTGCCAGGACCAGGGATGACTGGGCCATGGACACAGATGTCTCCAACCTTCAACCGTTTGCATAGCACACGGGGGACTCGT
GGGGGCCACCTGCCACTGCCAGCTGAAACAATACAATGGCAATACTGACATCCTTCATGACGTTTTCCCGACAGACATTCAGGCAGAAAG
TGCTGGTGCGTTTTCTGTCTGCAAAGTAGAGGGCCATGCCTCACCAATAGAATAGCGTGGGCCCTGATGACCTGCTCCGAGTCCACTCAC
AGCCAGTGACACTTGCAAAAAACTCCCAAAGCCGTCTTGGGTTTGGCTCCCACAGCTCTTGACCAATGTGGCCAAAGCTGGACACCTCCT
TGGGACACTGGGATTATTCATAAATGCAGCCCGCCCTGACTCTCCCTGAATAGCATCTGAAGTCTTTGTGAAGGTCATGGATCCTGAACA
AAGTGTCAAGGGCACCAAGAAGGCTGAGGGAAGTCCCCGGAAGCGGCTGACCAAAGGAGAGGCCATTCAGACCAGTGTTTCTTCCAGCGT
CCCATACCCAGGCAGCGGCACAGCTGCCACCCAAGAGAGCCCCGCCCAAGAGCTCTTAGCCCCGCAGCCCTTCCCGGGCCCCTCATCAGT
TCTTAGGGAAGGCTCTCAGGAGAAAACGGGCCAGCAGCAGAAGCCCCCCAAAAGGCCCCCCATCGAAGCATCCGTCCACATCTCACAGCT
TCCGCAGCACCCTCTGACACCAGCATTCATGTCGCCTGGCAAACCTGAGCATCTCCTGGAGGGGTCCACATGGCAACTGGTTGACCCCAT
GAGACCTGGACCCTCTGGCTCCTTCGTGGCCCCTGGGCTCCATCCTCAGAGCCAGCTCCTTCCTTCCCACGCTTCCATCATTCCCCCCGA
GGACCTTCCTGGAGTCCCCAAAGTCTTCGTGCCTCGTCCTTCCCAGGTCTCCTTGAAGCCCACAGAAGAGGCACACAAGAAGGAGAGGAA
GCCCCAGAAGCCAGGCAAGTACATCTGCCAGTACTGCAGCCGGCCCTGTGCCAAGCCCAGCGTGCTCCAGAAGCACATTCGCTCACACAC
AGGTGAGAGGCCCTACCCCTGCGGCCCCTGTGGCTTCTCCTTCAAGACCAAGAGTAATCTCTACAAGCACAGGAAGTCCCATGCCCACCG
CATCAAAGCAGGCCTGGCCTCAGGCATGGGTGGCGAGATGTACCCACATGGGCTGGAGATGGAGCGGATCCCTGGGGAAGAGTTTGAGGA
GCCCACTGAGGGAGAAAGCACAGATTCTGAAGAGGAGACTAGTGCCACCTCTGGTCACCCTGCAGAGCTCTCCCCAAGACCCAAGCAGCC
CCTTCTCTCCAGCGGGCTATACAGCTCTGGGAGCCACAGTTCCAGCCACGAACGCTGTTCCCTGTCCCAGTCCAGCACAGCCCAGTCACT
CGAAGACCCCCCTCCATTTGTGGAACCCTCATCTGAGCACCCCCTGAGCCATAAACCTGAAGACACCCACACGATTAAGCAGAAGCTGGC
CCTCCGCTTAAGCGAGAGGAAGAAGGTGATCGATGAGCAGGCGTTTCTGAGCCCAGGCAGCAAAGGGAGTACTGAGTCTGGGTATTTCTC
TCGCTCCGAGAGTGCAGAGCAGCAGGTCAGCCCCCCAAACACCAACGCCAAGTCCTACGCTGAGATCATCTTTGGCAAGTGTGGGCGAAT
AGGACAGCGGACCGCCATGCTGACAGCCACCTCCACCCAGCCCCTCCTGCCCCTGTCCACCGAAGACAAGCCCAGCCTGGTGCCTTTGTC
TGTACCCCGGACGCAGGTGATCGAGCACATCACGAAGCTCATCACCATCAACGAGGCCGTGGTGGACACCAGCGAGATCGACAGCGTGAA
GCCAAGGCGGAGCTCACTGTCCAGGCGCAGCAGCATGGAGTCCCCAAAATCCAGCCTCTACCGGGAGCCCCTGTCATCCCACAGTGAGAA
AACCAAGCCTGAACAATCACTGCTGAGCCTCCAGCACCCGCCCAGTACCGCCCCCCCTGTGCCTCTCCTGAGAAGCCACTCAATGCCTTC
TGCCGCCTGCACTATCAGCACCCCCCACCACCCCTTCCGAGGTAGCTACTCCTTCGATGACCATATCACCGACTCCGAAGCCCTGAGCCA
CAGCAGTCACGTGTTTACCTCCCACCCCCGGATGCTGAAGCGCCAGCCGGCAATCGAATTACCTTTGGGAGGGGAATACAGTTCTGAGGA
GCCTGGCCCAAGCAGCAAAGACACAGCCTCCAAGCCCTCGGACGAAGTGGAACCCAAGGAAAGCGAGCTTACCAAAAAGACCAAGAAGGG
TTTGAAAACAAAAGGGGTGATCTACGAATGTAACATATGTGGTGCTCGGTACAAGAAAAGGGATAACTACGAAGCCCACAAAAAATACTA
CTGCTCAGAGCTTCAGATCGCAAAGCCCATCTCTGCAGGCACCCACACATCTCCAGAAGCTGAAAAGAGTCAGATTGAGCATGAGCCGTG
GTCCCAAATGATGCATTACAAACTGGGAACCACCCTGGAACTCACTCCACTGAGGAAGAGGAGGAAAGAGAAGAGCCTTGGGGACGAGGA
AGAGCCACCTGCCTTTGAGTCCACAAAAAGTCAGTTTGGCAGCCCCGGGCCATCTGATGCTGCTCGGAACCTTCCCCTGGAGTCCACCAA
GTCACCAGCAGAACCAAGTAAATCAGTGCCCTCCTTGGAGGGACCCACGGGCTTCCAGCCAAGGACTCCCAAGCCAGGGTCCGGTTCAGA
ATCAGGGAAGGAGAGGAGAACAACGTCCAAAGAAATTTCTGTCATCCAGCACACCAGCTCCTTTGAGAAATCTGATTCTCTCGAGCAGCC
GAGTGGCTTGGAAGGGGAAGACAAACCTCTGGCCCAGTTCCCATCACCCCCACCTGCCCCACACGGACGCTCTGCTCACTCCCTGCAGCC
TAAGTTGGTCCGCCAGCCCAACATTCAGGTTCCTGAGATCCTAGTAACTGAGGAGCCTGACCGGCCGGACACAGAGCCAGAGCCGCCCCC
TAAGGAACCTGAGAAGACTGAGGAGTTCCAATGGCCCCAGCGCAGCCAGACACTTGCCCAGCTCCCAGCTGAGAAGCTGCCACCCAAAAA
GAAGAGGTTGCGCCTGGCAGAGATGGCCCAATCATCAGGGGAGTCCAGCTTCGAGTCCTCTGTGCCTCTGTCTCGCAGCCCGAGCCAGGA
AAGCAATGTCTCTTTGAGTGGGTCCAGCCGCTCAGCCTCGTTTGAGAGGGATGACCATGGGAAAGCCGAGGCCCCCAGTCCCTCATCTGA
CATGCGCCCCAAACCCCTGGGCACCCACATGTTGACTGTCCCCAGCCACCACCCACATGCCCGAGAGATGCGGAGGTCAGCCTCAGAGCA
GAGCCCCAACGTTTCCCATTCTGCCCACATGACCGAGACACGCAGCAAATCCTTTGACTATGGCAGCTTGTCCTTGACAGGCCCTTCTGC
TCCAGCCCCAGTGGCTCCACCAGCGCGGGTGGCCCCGCCAGAGAGAAGAAAATGCTTCTTGGTGAGACAGGCCTCTCTGAGCAGGCCTCC
AGAATCTGAGTTGGAGGTTGCCCCCAAGGGAAGACAGGAGAGCGAAGAACCACAGCCCTCATCCAGTAAACCCTCTGCCAAAAGCTCATT
GTCCCAGATTTCCTCTGCGGCCACCTCACATGGTGGACCCCCGGGAGGCAAGGGCCCAGGGCAGGACAGGCCCCCATTGGGGCCCACTGT
GCCCTACACAGAAGCACTGCAAGTGTTCCACCACCCCGTTGCCCAGACACCCCTGCATGAGAAGCCATACCTGCCCCCACCAGTCTCCCT
TTTCTCCTTCCAGCATCTCGTGCAGCATGAGCCAGGACAGTCTCCAGAATTCTTCTCCACCCAGGCCATGTCCAGCCTCCTGTCCTCACC
ATACTCCATGCCCCCACTTCCTCCCTCCTTATTTCAAGCCCCACCGCTTCCTCTCCAGCCTACTGTTCTGCACCCAGGCCAACTCCATCT
CCCCCAGCTCATGCCTCACCCAGCCAACATCCCCTTCAGGCAGCCCCCTTCCTTCCTCCCCATGCCATACCCGACCTCCTCAGCACTGTC
TTCTGGGTTTTTCCTGCCTCTGCAATCCCAGTTTGCACTTCAGCTCCCTGGTGATGTGGAAAGCCATCTGCCCCAGATCAAAACCAGCCT
GGCCCCACTGGCAACAGGAAGTGCTGGCCTCTCCCCCAGCACAGAGTACAGCAGTGACATCCGGCTACCCCCTGTGGCTCCCCCAGCCAG
CTCCTCAGCACCTACATCAGCTCCTCCACTGGCCCTGCCTGCCTGTCCAGACACCATGGTGTCCCTGGTTGTGCCTGTCCGTGTTCAGAC
CAATATGCCGTCCTATGGGAGCGCAATGTACACCACCCTTTCCCAGATCTTGGTCACCCAGTCCCAAGGCAGCTCAGCAACTGTGGCACT
TCCCAAGTTTGAGGAACCCCCATCAAAGGGGACGACTGTATGTGGTGCAGATGTGCATGAGGTTGGGCCCGGCCCTTCTGGGTTAAGTGA
AGAGCAAAGCAGAGCTTTCCCAACTCCATACCTGAGAGTGCCTGTGACATTACCTGAAAGAAAAGGCACTTCCCTGTCATCAGAGAGTAT
CTTGAGCCTGGAGGGGAGTTCATCAACAGCAGGGGGAAGCAAACGTGTCCTTTCACCAGCTGGCAGCCTTGAACTTACCATGGAAACCCA
GCAGCAAAAAAGAGTGAAGGAGGAGGAGGCTTCCAAGGCAGATGAAAAACTTGAGCTGGTAAAACCATGCAGTGTGGTCCTTACCAGCAC
CGAGGATGGGAAGAGGCCAGAGAAATCCCACTTAGGCAACCAGGGCCAAGGCAGGAGGGAGCTAGAAATGCTGTCCAGCCTGTCCTCAGA
TCCATCTGACACAAAGGAAATTCCTCCCCTCCCTCACCCTGCATTGTCCCATGGGACAGCCCCAGGCTCAGAAGCTTTGAAGGAATATCC
CCAGCCATCTGGCAAACCTCACCGAAGAGGGTTGACCCCACTGAGCGTGAAGAAAGAAGATTCCAAGGAACAACCTGATCTCCCCTCCTT
GGCACCTCCGAGCTCTCTGCCTCTGTCAGAAACGTCCTCCAGACCAGCCAAGTCACAAGAAGGTACGGACTCAAAGAAGGTACTGCAGTT
CCCCAGCCTCCACACAACCACTAATGTCAGTTGGTGCTATTTAAACTACATTAAGCCAAATCACATCCAGCATGCAGATAGGAGGTCCTC
TGTTTACGCTGGTTGGTGCATAAGTTTGTACAACCCCAACCTTCCGGGGGTTTCCACTAAAGCTGCTTTGTCCCTCCTGAGGTCTAAGCA
GAAAGTGAGCAAAGAGACATACACCATGGCCACAGCTCCGCATCCTGAGGCAGGAAGGCTTGTGCCATCCAGCTCCCGCAAGCCCCGCAT
GACAGAGGTTCACCTCCCTTCACTGGTTTCCCCGGAAGGCCAGAAAGATCTAGCTAGAGTGGAGAAGGAAGAAGAGAGGAGAGGGGAGCC
GGAGGAGGATGCTCCTGCCTCCCAGAGAGGGGAGCCGGCGAGGATCAAAATCTTCGAAGGAGGAAGGAGTTTTGGAGCACCTACACAAAA
GCGCAACAAGGGGAGAGTAACCGAGGAAGTGACTGGTTTCAGTTTTACCTTACCTTTCCGTTAATCTTTGGCCTCTTCATTATCCTCCTT
GTCATTTTCCTAATCTGGAGATGCTTCCTAAGAAACAAAACTCGTAGACAGACAGTGACTGAAGGCCACATTCCTTTCCCTCAGCACCTT
AATATTATCACCCCACCCCCCCCACCAGATGAAGTGTTTGACAGCAGTGGATTGTCTCCAGGCTTTCTGGGATATGTAGTTGGGCGCTCA
GATTCCGTCTCTACTCGCCTGTCCAATTGTGATCCCCCGCCAACCTATGAGGAAGCCACTGGCCAAGTGAACCTGCAGAGGAGTGAAACA
GAACCTCATTTAGACCCACCCCCAGAGTATGAGGACATAGTCAACTCCAACTCAGCCAGTGCCATTCCTATGGTGCCTGTGGTCACCACC
ATCAAATGAAGCTGCAAACTTCTTTTTACTCTAATCATTTTTAAAATACTAATGGAAGAACTTTCTAGCACTTTACCACTACATAAATGT
TCATTGACTTATTTTATTGGACTCTTACCGCATACCACTTCACACTTGTTTTATTTTCTTTAGTTTTGTTTCTTGTTATAGAATCATTAT
CCATGCTCATTTTTGCTAGGGGAAATATATGAAGAGGGAAAACATACTAATGGGGGTCTTTCTGTGATGTGATGAGACATACATGTAAGT
GTATATATGTGTGTATAGGCATATATACGTGTGTATGCATCAACACAGTATATGTAAAACTGTCTTAAAAATCCATTAACTTCTACCTAA
ATCACCTGGAAGGAGAGCATTACTCACCAAAATTGCAAAACAAGGGTATCAAGAATTTGTGTAATAGCCAGTGACATGCTGTAGATTTTT
GCAAACTGGATGTACTTAGCATGTTTTCTAATTCTGACTGGCTTTTGTTAACTTGATAATTCTTCATCTACCTTAAAAAGAAAAAAATTA
CACATAGTCATTCTTGATGTTATAAATAGAGAAAAAGTGTGTGTGAGCAATAATGCATAAGCTACTGATAACTTGCTTACAGCAGATAGC
AATAAGGTATTTGGTGGCATTCGGCTTGTTTTGTAATAGGGATTTTTTTTTTGGTTGACCACTCCCCCACACTTCCAAAATTAAACAGTG
TTTTCTTAGCATCTTGAATATCTCCTGCGGTGTATATTAACATCTTGATGAGACAGATTTCCAGGCAACAAAATAATTTCTAAAATGGAT
ATATGTGTGGATTAATGACAGGCAGTAAATACCCATTACTCCTTTACTCATAGCTGGTAAAATTATTCCCACTGTTTTATTGCCTTTTAC
TGTACGTTCTACACTCTGTCCTACTCCCACAGAATTTTCAAGCCCTTAAGAGTTTAGTTAAAATAAAATTTTTGAAATTATTGTCTTAAT
ATTTTTATATAGGCTGATGTCTTTGCCTCAAGATTGTTAGGAGGTAATTTTCCATTGAATTATCAACTGTGATTTTTATATTGCCCTCCA
AGTGGTAGAAGAAGATTGCAAAGTCCATGTTATGCTAGGTGCACAATAAATCTAGTAATAGCCCCACACAGATCTCATCATTGTTGCTAC
TTCCTTTTGTATTTTCATCAGGTATTTTTTTAACTGTAGGGTTTTTACTTTTTTCTTGGAGCAGAGAGAACAGGCTGTAAATGGGTTGCC
AACATAAGCTGGCTGAGAAATAAAAGAAAACAAGACAGTTGTTCATAAAGTTTCATTTTGTATGCACTGATGGCAAATTCATTAGGTCAG
TTAAGGGAAATATTTGTACCACTTCCAAACTTTTCAGCGTTGGATAAAATGATTGATGAGGCAGGCAGAAGGAATGTAGGTTTCAGGTGT
GTCATTTCCTGCTGCTTCCAGCTCCATCCCTACAGACTCCTCCCCGAGTCCTGCCCTGGAACCAAAGGAAGGAGGAACACTGAGGGGAAT
CCTGAAGTAGGAGTCAGATGACCTGAACTCAGATCTCCCTCTATCACATGCTTGCCACCACTGTACCTTGAGCAAGAATCATATCTGACC
CTCAACCTCCTCAACTCTAAAATGGGGATAACATCATTTGTCCTGCACTTCTCTAAGGGCTTTACAAGGATCAAATAAGATGGTGTGTAT
GTAAGAAATTTGTAAAATGTGAAGAGCTATCTACACTAAGTTCGTAATGTTATTATTATTGTGCTTCATGGAGAATTTTCCCCTCTGTTT
TCCTAAATTGTATGAGAGCTTTCACACAGTGAGAAATAGAGCAGGCTGCCCCATAAATGGGTAACATATTCCTAATCTGAGTGTGTGGGC
TGTTAGAGAACCCCTGCCATGCTCTGGTCTGTTCTGAAACTGTGCCAACTGAAAGATGATAGTCCACACAGCACAAACAGGTTTAAGCAA
ATGATAGAAAGGGAAGTAAGGCGTGTGTGCTAGTTAATAGGTTTAGTAGCTTTTATGGACTAAAAATGATTGATTGTATCTTGACCCTGG
TCTCAGAAATGACATTTTTACTTTTGCCATGAGTACACATCAGATATCTTTGGCTTCTATTTAAAGCTAAAGGTAGAAGTGTTTGATCCA
GTGAACTGTGTATGTATGTGTGGGGTTTTTTTCTTTATTTTTAAATGAAAATTAAGACACCTTTTGTGTGGACATGTTTTTGTCTTTAAT
GTCAGGCTTTAGATTAGACCAGCAGTTTTCAAAGTATGGCCAATGGACCCCTGGGTTCCTTGAGAGCCTTTCAGGGGGGACTATGAGATC
AAAATATTTTTATTATAATGTGAAGACATTGTCTTTTCACTCTATCTCAAAAAAAGTGTTGCAAATGTAAAACATTGCCATCTTCTCACA
AATCTCTTTTTTTGTTTTTGAAAATATGGCCATTTTTCATAAAATGTTATTTGTGTTAGCATGTAATGGGTTTACTATGTTTAAATAAGT
TAATACTTTAAAAATTTTCAGGTTTTTTTAGTATGGTGAATATTGATAGATATAAACCTCATGAACAAAAGTACTTTGGCATCCAGATTC
TCAATAAATGTTAAGAGCGTAAGTGTAAGGGGGTCCAGAGACCAAAAGTTTTAGAGCTACAGGATTAGACATAGGAGCAGGATATTCTGT
TAGTGTGATTTCTTGCAACTTTATTTTACATTTTAAACTGCTGATATTGGATATAATGCTGCTTTTTAGAGACACCTAAATTGCAGTATC
AGAATGAATGTTGATGTTTGAAGCCAAAAAGCCAAATGCTTAAACTGATCAATGACTGTAGCTTTTTAGACTGTTGGTCAAAGAACATTC
TACTTCACAGTAATAGCTCTATCAGCCACAGATCTCATGGTGGCTGTTGCATGATAATGATAGGATAAACAAAATACCACTGTCTTCAAG
AAACATTATCTTAGGTTTGTTTGTTTGGTTTGAGTTTGATTTGGCTTTTATATTTTTTAAAATCCCTTTTGCTACCCCATCTGGTTTTAT
AAACTGAGTTTCTTAGCATTCGTTAAAATTAAGGGGTTTGTTTGGAATAATATATATTTTTTATGCTTTTGTCTTTCTTACCTGATTGAT
ATTACATTCACCTTTGATTGTTTTTTAAAAGTTTATTTTTACAGAATATATTTAGTACCTTTCTTAAGGAGTAACTGAATTGAATCAACC
AGTTTGCATTTAAATAAAAGAACAGGCTCAGTGGTCTTCCTGTAGAATGGTTTACATGCCTGCATGTGCAGTAGTTGTGTCTGGAATCCT
AGAATTGGCACTTTCTGCCTCCTTGCTCTAAATGTCACAAAAAATTATACTTCCTTAAAGTAAATGTAATGATTTCTTCTTTTCCTATTG
ACCAGTACAGATAGATATGTTGTGTTTGCTTCATTTTTAATGATGACTTCAAGATTGATGATGTGATCCAATAACTGTGGAGGTAGCTTT
AACTTGGTTCTGTGTAAATAGTATGTATTTTATTATAATATTTCTCATTTTAAGATGCTTGGTTTACATTAAATTATGGTATTTAACTAT

>36563_36563_1_HIVEP3-PRRG1_HIVEP3_chr1_42041215_ENST00000372583_PRRG1_chrX_37312389_ENST00000378628_length(amino acids)=1765AA_BP=1736
MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEASV
HISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAH
KKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPG
EEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTI
KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPS
LVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRS
HSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDTASKPSDEVEPKESELTK
KTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKS
LGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSD
SLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEK
LPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRR
SASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS
AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSS
LLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ
IKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSS
ATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLEL
TMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEA
LKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHA
DRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEE

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for HIVEP3-PRRG1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for HIVEP3-PRRG1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for HIVEP3-PRRG1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource