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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:HK1-CTNNA3 (FusionGDB2 ID:36572)

Fusion Gene Summary for HK1-CTNNA3

check button Fusion gene summary
Fusion gene informationFusion gene name: HK1-CTNNA3
Fusion gene ID: 36572
HgeneTgene
Gene symbol

HK1

CTNNA3

Gene ID

255061

29119

Gene nametachykinin precursor 4catenin alpha 3
SynonymsEK|HK-1|HK1|PPT-CARVD13|VR22
Cytomap

17q21.33

10q21.3

Type of geneprotein-codingprotein-coding
Descriptiontachykinin-4endokininpreprotachykinin-Ctachykinin 4 (hemokinin)catenin alpha-3alpha-T-cateninalpha-catenin-like proteincatenin (cadherin-associated protein), alpha 3
Modification date2020031320200313
UniProtAcc.

Q9UI47

Ensembl transtripts involved in fusion geneENST00000359426, ENST00000298649, 
ENST00000360289, ENST00000404387, 
ENST00000448642, ENST00000494253, 
ENST00000373735, ENST00000545309, 
ENST00000373744, ENST00000433211, 
Fusion gene scores* DoF score15 X 16 X 5=120023 X 20 X 6=2760
# samples 2125
** MAII scorelog2(21/1200*10)=-2.51457317282976
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(25/2760*10)=-3.46466826700344
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: HK1 [Title/Abstract] AND CTNNA3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointHK1(71078766)-CTNNA3(68535282), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneHK1

GO:1902093

positive regulation of flagellated sperm motility

17437961


check buttonFusion gene breakpoints across HK1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CTNNA3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-EJ-8469-01AHK1chr10

71078766

-CTNNA3chr10

68535282

-
ChimerDB4PRADTCGA-EJ-8469-01AHK1chr10

71078766

+CTNNA3chr10

68535282

-
ChimerDB4PRADTCGA-EJ-8469HK1chr10

71078766

+CTNNA3chr10

68535282

-


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Fusion Gene ORF analysis for HK1-CTNNA3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000359426ENST00000373735HK1chr10

71078766

+CTNNA3chr10

68535282

-
5CDS-intronENST00000359426ENST00000545309HK1chr10

71078766

+CTNNA3chr10

68535282

-
In-frameENST00000359426ENST00000373744HK1chr10

71078766

+CTNNA3chr10

68535282

-
In-frameENST00000359426ENST00000433211HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-3CDSENST00000298649ENST00000373744HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-3CDSENST00000298649ENST00000433211HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-3CDSENST00000360289ENST00000373744HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-3CDSENST00000360289ENST00000433211HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-3CDSENST00000404387ENST00000373744HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-3CDSENST00000404387ENST00000433211HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-3CDSENST00000448642ENST00000373744HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-3CDSENST00000448642ENST00000433211HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-3CDSENST00000494253ENST00000373744HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-3CDSENST00000494253ENST00000433211HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-intronENST00000298649ENST00000373735HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-intronENST00000298649ENST00000545309HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-intronENST00000360289ENST00000373735HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-intronENST00000360289ENST00000545309HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-intronENST00000404387ENST00000373735HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-intronENST00000404387ENST00000545309HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-intronENST00000448642ENST00000373735HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-intronENST00000448642ENST00000545309HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-intronENST00000494253ENST00000373735HK1chr10

71078766

+CTNNA3chr10

68535282

-
intron-intronENST00000494253ENST00000545309HK1chr10

71078766

+CTNNA3chr10

68535282

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000359426HK1chr1071078766+ENST00000433211CTNNA3chr1068535282-9620167501807585
ENST00000359426HK1chr1071078766+ENST00000373744CTNNA3chr1068535282-2119167501807585

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000359426ENST00000433211HK1chr1071078766+CTNNA3chr1068535282-0.0003740930.9996259
ENST00000359426ENST00000373744HK1chr1071078766+CTNNA3chr1068535282-0.0022107040.99778926

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Fusion Genomic Features for HK1-CTNNA3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for HK1-CTNNA3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:71078766/chr10:68535282)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CTNNA3

Q9UI47

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May be involved in formation of stretch-resistant cell-cell adhesion complexes. {ECO:0000303|PubMed:11590244}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+1181_1021918.0RegionMitochondrial-binding peptide (MBP)

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+11816_4580917.0DomainHexokinase 1
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118464_9060917.0DomainHexokinase 2
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+11816_45821918.0DomainHexokinase 1
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118464_90621918.0DomainHexokinase 2
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+12216_4580906.0DomainHexokinase 1
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122464_9060906.0DomainHexokinase 2
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+11916_4580922.0DomainHexokinase 1
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119464_9060922.0DomainHexokinase 2
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118425_4260917.0Nucleotide bindingATP 1
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118532_5370917.0Nucleotide bindingATP 2
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118747_7480917.0Nucleotide bindingATP 2
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118784_7880917.0Nucleotide bindingATP 2
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+11884_890917.0Nucleotide bindingATP 1
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118425_42621918.0Nucleotide bindingATP 1
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118532_53721918.0Nucleotide bindingATP 2
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118747_74821918.0Nucleotide bindingATP 2
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118784_78821918.0Nucleotide bindingATP 2
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+11884_8921918.0Nucleotide bindingATP 1
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122425_4260906.0Nucleotide bindingATP 1
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122532_5370906.0Nucleotide bindingATP 2
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122747_7480906.0Nucleotide bindingATP 2
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122784_7880906.0Nucleotide bindingATP 2
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+12284_890906.0Nucleotide bindingATP 1
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119425_4260922.0Nucleotide bindingATP 1
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119532_5370922.0Nucleotide bindingATP 2
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119747_7480922.0Nucleotide bindingATP 2
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119784_7880922.0Nucleotide bindingATP 2
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+11984_890922.0Nucleotide bindingATP 1
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118172_1730917.0RegionSubstrate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+1181_100917.0RegionMitochondrial-binding peptide (MBP)
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118208_2090917.0RegionSubstrate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118208_4470917.0RegionHexokinase large subdomain 1
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118291_2940917.0RegionSubstrate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118413_4150917.0RegionGlucose-6-phosphate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118521_6550917.0RegionHexokinase small subdomain 2
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118532_5360917.0RegionGlucose-6-phosphate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118603_6040917.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118620_6210917.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118656_6570917.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118656_8950917.0RegionHexokinase large subdomain 2
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118682_6830917.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+11873_2070917.0RegionHexokinase small subdomain 1
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+11884_910917.0RegionGlucose-6-phosphate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000298649+118861_8630917.0RegionGlucose-6-phosphate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118172_17321918.0RegionSubstrate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118208_20921918.0RegionSubstrate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118208_44721918.0RegionHexokinase large subdomain 1
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118291_29421918.0RegionSubstrate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118413_41521918.0RegionGlucose-6-phosphate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118521_65521918.0RegionHexokinase small subdomain 2
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118532_53621918.0RegionGlucose-6-phosphate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118603_60421918.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118620_62121918.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118656_65721918.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118656_89521918.0RegionHexokinase large subdomain 2
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118682_68321918.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+11873_20721918.0RegionHexokinase small subdomain 1
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+11884_9121918.0RegionGlucose-6-phosphate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000359426+118861_86321918.0RegionGlucose-6-phosphate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122172_1730906.0RegionSubstrate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+1221_100906.0RegionMitochondrial-binding peptide (MBP)
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122208_2090906.0RegionSubstrate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122208_4470906.0RegionHexokinase large subdomain 1
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122291_2940906.0RegionSubstrate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122413_4150906.0RegionGlucose-6-phosphate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122521_6550906.0RegionHexokinase small subdomain 2
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122532_5360906.0RegionGlucose-6-phosphate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122603_6040906.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122620_6210906.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122656_6570906.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122656_8950906.0RegionHexokinase large subdomain 2
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122682_6830906.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+12273_2070906.0RegionHexokinase small subdomain 1
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+12284_910906.0RegionGlucose-6-phosphate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000360289+122861_8630906.0RegionGlucose-6-phosphate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119172_1730922.0RegionSubstrate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+1191_100922.0RegionMitochondrial-binding peptide (MBP)
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119208_2090922.0RegionSubstrate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119208_4470922.0RegionHexokinase large subdomain 1
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119291_2940922.0RegionSubstrate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119413_4150922.0RegionGlucose-6-phosphate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119521_6550922.0RegionHexokinase small subdomain 2
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119532_5360922.0RegionGlucose-6-phosphate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119603_6040922.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119620_6210922.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119656_6570922.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119656_8950922.0RegionHexokinase large subdomain 2
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119682_6830922.0RegionSubstrate 2 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+11973_2070922.0RegionHexokinase small subdomain 1
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+11984_910922.0RegionGlucose-6-phosphate 1 binding
HgeneHK1chr10:71078766chr10:68535282ENST00000404387+119861_8630922.0RegionGlucose-6-phosphate 2 binding
TgeneCTNNA3chr10:71078766chr10:68535282ENST00000373744517325_379349896.0Coiled coilOntology_term=ECO:0000255
TgeneCTNNA3chr10:71078766chr10:68535282ENST0000037374451774_111349896.0Coiled coilOntology_term=ECO:0000255
TgeneCTNNA3chr10:71078766chr10:68535282ENST00000433211618325_379349896.0Coiled coilOntology_term=ECO:0000255
TgeneCTNNA3chr10:71078766chr10:68535282ENST0000043321161874_111349896.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for HK1-CTNNA3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>36572_36572_1_HK1-CTNNA3_HK1_chr10_71078766_ENST00000359426_CTNNA3_chr10_68535282_ENST00000373744_length(transcript)=2119nt_BP=167nt
GAGGAGGAGGAGCCGCCGAGCAGCCGCCGGAGGACCACGGCTCGCCAGGGCTGCGGAGGACCGACCGTCCCCACGCCTGCCGCCCCGCGA
CCCCGACCGCCAGCATGATCGCCGCGCAGCTCCTGGCCTATTACTTCACGGAGCTGAAGGATGACCAGGTCAAAAAGGCTGGAAAAAAAG
AAAGGAGTAATACCCTGAATATTGCTTTAGACAACATGTGTAAGAAGACAAGAGACCTTCGCAGACAGCTCCGCAAGGCTATTATAGATC
ATGTGTCAGACTCTTTCCTGGATACGACAGTCCCTCTTTTGGTTCTCATTGAAGCTGCTAAGAATGGCCGGGAAAAGGAAATAAAAGAAT
ATGCTGCGATATTTCATGAACACACCAGCAGGCTTGTAGAGGTGGCAAATCTTGCTTGTTCCATGTCAACAAATGAAGATGGAATTAAAA
TTGTCAAAATTGCAGCCAATCATTTGGAAACCTTGTGTCCACAGATTATTAATGCTGCACTTGCTTTGGCTGCAAGACCCAAAAGTCAAG
CGGTCAAAAACACCATGGAAATGTACAAGCGTACATGGGAGAATCATATACATGTCCTCACTGAAGCCGTAGATGACATTACAAGCATTG
ATGACTTCCTTGCTGTATCTGAAAGCCATATCTTGGAAGATGTCAACAAGTGTATCATAGCCTTAAGAGACCAGGATGCTGATAATTTAG
ACCGTGCTGCGGGTGCTATCAGAGGCCGGGCAGCAAGAGTTGCTCACATCGTCACGGGTGAAATGGACAGTTACGAGCCAGGGGCTTACA
CGGAAGGTGTAATGAGAAATGTTAACTTCCTTACAAGTACTGTAATTCCTGAATTTGTAACACAAGTGAATGTTGCCTTGGAAGCCTTAA
GCAAAAGCTCATTGAATGTGTTGGATGATAATCAATTTGTGGACATCTCAAAGAAGATCTATGATACAATTCATGATATCAGATGTTCAG
TCATGATGATTCGGACCCCAGAGGAACTGGAGGATGTTTCTGACCTTGAAGAGGAACACGAGGTCCGCAGTCACACCAGCATTCAGACCG
AAGGGAAAACTGATAGGGCTAAGATGACTCAACTGCCTGAGGCAGAAAAAGAAAAGATTGCTGAGCAAGTTGCTGATTTCAAGAAAGTAA
AGAGTAAGCTGGATGCTGAGATTGAGATATGGGATGATACAAGCAACGACATCATTGTTCTGGCCAAGAACATGTGTATGATCATGATGG
AGATGACAGACTTCACTAGGGGCAAAGGACCACTAAAGCATACAACTGATGTGATCTATGCAGCGAAAATGATATCAGAATCAGGATCAA
GGATGGATGTCCTTGCTCGGCAGATTGCTAATCAGTGCCCAGATCCATCTTGTAAACAGGACTTGTTGGCCTACCTGGAACAGATTAAGT
TCTACTCCCACCAACTGAAAATCTGCAGTCAAGTTAAAGCTGAGATCCAGAACCTGGGAGGAGAGCTCATCATGTCAGCTTTGGACAGTG
TCACATCCCTGATCCAAGCAGCCAAAAATTTAATGAATGCTGTAGTGCAAACAGTGAAAATGTCTTACATTGCCTCAACCAAGATCATCC
GAATCCAGAGTCCTGCTGGGCCCCGGCACCCAGTTGTGATGTGGAGAATGAAGGCTCCTGCAAAAAAACCCTTGATTAAAAGAGAGAAGC
CAGAGGAAACGTGTGCAGCTGTCAGACGAGGCTCAGCAAAGAAAAAAATCCATCCATTGCAAGTCATGAGTGAATTTAGAGGAAGACAAA
TCTACTGAAACCACTATTCTACATATAGTGCCTATATGACAAAATCCTGCCTAACCACACTGCTTTATTTTACACTTAAGAAGTTCTGTA
ATTTCACTAAGTTTTGGTGTTTAACTCACAAATAACATAAAATATTGGGCGCTAAATCAACAAAAGCAATATATATTTGGGATCATATCA
CTGTCATTTCTGTATGGTCAGCACCTAATAGTTAAGGAATATTTGCTTGTTGAATGAATGAAATTATCACGTGTCATTCAGCGTTTCCCA

>36572_36572_1_HK1-CTNNA3_HK1_chr10_71078766_ENST00000359426_CTNNA3_chr10_68535282_ENST00000373744_length(amino acids)=585AA_BP=39
MRRTDRPHACRPATPTASMIAAQLLAYYFTELKDDQVKKAGKKERSNTLNIALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLI
EAAKNGREKEIKEYAAIFHEHTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTMEMYKRTWENHI
HVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIP
EFVTQVNVALEALSKSSLNVLDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEHEVRSHTSIQTEGKTDRAKMTQLPEAEK
EKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPS
CKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPAGPRHPVVMWRM

--------------------------------------------------------------
>36572_36572_2_HK1-CTNNA3_HK1_chr10_71078766_ENST00000359426_CTNNA3_chr10_68535282_ENST00000433211_length(transcript)=9620nt_BP=167nt
GAGGAGGAGGAGCCGCCGAGCAGCCGCCGGAGGACCACGGCTCGCCAGGGCTGCGGAGGACCGACCGTCCCCACGCCTGCCGCCCCGCGA
CCCCGACCGCCAGCATGATCGCCGCGCAGCTCCTGGCCTATTACTTCACGGAGCTGAAGGATGACCAGGTCAAAAAGGCTGGAAAAAAAG
AAAGGAGTAATACCCTGAATATTGCTTTAGACAACATGTGTAAGAAGACAAGAGACCTTCGCAGACAGCTCCGCAAGGCTATTATAGATC
ATGTGTCAGACTCTTTCCTGGATACGACAGTCCCTCTTTTGGTTCTCATTGAAGCTGCTAAGAATGGCCGGGAAAAGGAAATAAAAGAAT
ATGCTGCGATATTTCATGAACACACCAGCAGGCTTGTAGAGGTGGCAAATCTTGCTTGTTCCATGTCAACAAATGAAGATGGAATTAAAA
TTGTCAAAATTGCAGCCAATCATTTGGAAACCTTGTGTCCACAGATTATTAATGCTGCACTTGCTTTGGCTGCAAGACCCAAAAGTCAAG
CGGTCAAAAACACCATGGAAATGTACAAGCGTACATGGGAGAATCATATACATGTCCTCACTGAAGCCGTAGATGACATTACAAGCATTG
ATGACTTCCTTGCTGTATCTGAAAGCCATATCTTGGAAGATGTCAACAAGTGTATCATAGCCTTAAGAGACCAGGATGCTGATAATTTAG
ACCGTGCTGCGGGTGCTATCAGAGGCCGGGCAGCAAGAGTTGCTCACATCGTCACGGGTGAAATGGACAGTTACGAGCCAGGGGCTTACA
CGGAAGGTGTAATGAGAAATGTTAACTTCCTTACAAGTACTGTAATTCCTGAATTTGTAACACAAGTGAATGTTGCCTTGGAAGCCTTAA
GCAAAAGCTCATTGAATGTGTTGGATGATAATCAATTTGTGGACATCTCAAAGAAGATCTATGATACAATTCATGATATCAGATGTTCAG
TCATGATGATTCGGACCCCAGAGGAACTGGAGGATGTTTCTGACCTTGAAGAGGAACACGAGGTCCGCAGTCACACCAGCATTCAGACCG
AAGGGAAAACTGATAGGGCTAAGATGACTCAACTGCCTGAGGCAGAAAAAGAAAAGATTGCTGAGCAAGTTGCTGATTTCAAGAAAGTAA
AGAGTAAGCTGGATGCTGAGATTGAGATATGGGATGATACAAGCAACGACATCATTGTTCTGGCCAAGAACATGTGTATGATCATGATGG
AGATGACAGACTTCACTAGGGGCAAAGGACCACTAAAGCATACAACTGATGTGATCTATGCAGCGAAAATGATATCAGAATCAGGATCAA
GGATGGATGTCCTTGCTCGGCAGATTGCTAATCAGTGCCCAGATCCATCTTGTAAACAGGACTTGTTGGCCTACCTGGAACAGATTAAGT
TCTACTCCCACCAACTGAAAATCTGCAGTCAAGTTAAAGCTGAGATCCAGAACCTGGGAGGAGAGCTCATCATGTCAGCTTTGGACAGTG
TCACATCCCTGATCCAAGCAGCCAAAAATTTAATGAATGCTGTAGTGCAAACAGTGAAAATGTCTTACATTGCCTCAACCAAGATCATCC
GAATCCAGAGTCCTGCTGGGCCCCGGCACCCAGTTGTGATGTGGAGAATGAAGGCTCCTGCAAAAAAACCCTTGATTAAAAGAGAGAAGC
CAGAGGAAACGTGTGCAGCTGTCAGACGAGGCTCAGCAAAGAAAAAAATCCATCCATTGCAAGTCATGAGTGAATTTAGAGGAAGACAAA
TCTACTGAAACCACTATTCTACATATAGTGCCTATATGACAAAATCCTGCCTAACCACACTGCTTTATTTTACACTTAAGAAGTTCTGTA
ATTTCACTAAGTTTTGGTGTTTAACTCACAAATAACATAAAATATTGGGCGCTAAATCAACAAAAGCAATATATATTTGGGATCATATCA
CTGTCATTTCTGTATGGTCAGCACCTAATAGTTAAGGAATATTTGCTTGTTGAATGAATGAAATTATCACGTGTCATTCAGCGTTTCCCA
TCATAGAGATTATCTACTATTCGTTACCAAATAAACACAGGAGAGGCCAGAGAGTCCTGTTTATCTGTAATACTTCATGTACACTTATCA
TCCTTATCTTGAATTAAAACACTAACATGAGCTCCTAACTTGGTTTTTTAATAGAAACAAAAGACTTTTATAAAATATTTTCCCATTTAA
TCTCCATGCTTTCTTTATCTGATCTAACCTGGCACCTAACCAGGCAGAAATGTATGATTCCTGCCATAGCAAAAAAACCACCTTTTAATC
TCTAGATAGCTGTACTCATTGTCAACTTATTAGGCTAATATCCATTATAAACTAATCAAATTTGAATAGTTAGGCTACTTGCTGGATTTT
GAAGGTCAACCTTGTTTATTAATAAAATGCTTTCTTAACATTATAAAGGTTACAATGAGTTCTGATGCCACATACTCACCTTTTGGGTTT
CCAATGTGTTAGAGAGTTCTGTACTTTTGAGTGTTAGGCCTATCCGAATACATATGTGAAAGAAGAGTTATCACCCATTGGGAAAATGAG
ACAACAAACTATATCCCAAAGTGAGTTATATTAATAATAACAGAAGTGTAAGTTCTGTATGACCCTATTTTTACAAACATAAAAATACAT
TTTTATCAGCTTGCAATTGTAATTAAAAGGAAAATGGCAGTTTGAAAAATCTTTTGACGTTGAGTAAAATATAACTGCATGAACTGTACC
ATTGAACTATGAAGCAGTTAATGGCAATGAAGCTGGAGTGATTTTAATAACGTTCTTTTAAATAAAAGTCACTGGGGTCATTTTACAACT
CCAGTCACTGTGTTCATTCCTAGTTGAGTTCATAATGGACTTCATAATAGTCTTAGAGTCTAGTGTACCTCTCTCTGTCATTCTCTCTCT
CTTTTTCTCTCCCCTGATGACCTGCCTCTCTCTGTCTTTCAAAAATGTCCTTAACAGAAACTCTTTGGAGGCCATAAGTTTTGTTTTCAT
TTTTTCTCATTCATAGAGTTCTGATTCACAGACTTTAAAAAACATTTTCTATTCTACATTATCATAATAGTATTATATTGTACCTTTTTA
CTTCTAAAACATTGCCATTGATGAGAGGCGTCTCAGCAACGATGTAACCTTAGATTGATGAGAAAAAAATTTACACATACAATACCAGTT
GATATTAGGAGAACCAGTTTGGGTAAAAGGATGCATGAAACATAGAAAAGCATAAAGATTGACAGTACGATATGTGTGGAATCTTAAGCA
TAATGGTATGGGAAAAGAAGGATCTATTTAATAGGTCATTATTAATTATGCAGGAAATGTTAAATTTCTTGTAATGAATTATTTCAATCT
TCCAAGTAGCTGGATTGCCTGAGCTCAGTGTAAAACTTCCTAGGAGGTGAAGGCAATAAACTCCTCCCTGTTTTGCACCATAGACTGGCC
TACAATAACTATTCTGAACAGAATGCACTGCCCAGAAGAAAAGGCAGTGAAGAAGGGAATTAGGGAATTCAGATGACTCTGTTTTTCAGA
ATTATCTAGATGATTGAGGCAAATAGAGATTTTCTTTTATTGAAATGCTGCCATCATTTTCTGCTCTAAGTGTAGATGTTGCACGAGTGA
CATCTGTGGTATATCCTTCTTCCAGATAGAAGTATAAATTTATAATTTAGTGGGGAGAGGAATTTTCTTTTAATCACCAAACTACCAGCT
GTATAGAAAATTTTTTTGAAATCACCAAACTAGCAGTTGTGTATCTTAGCTCCTAAAGCCACATTCACAAGAATCATAAGCATCTCATTT
AGAAAATCTAATGTCCACCGGACCCAACATCATCTTTCCACATGTTGGAGTTTAGAACATGCAGTATTGGACACCAAAAGAACAGAAATA
ACTTGAAATTATACAATTACCAAATAACCTCCATCTCTTTGATAAAAATGACTTTTTACCCAAAGTGAGATGTGAACAAGTTCTCCTCTT
TAACCCAGGCAGATTTTCAGCTTAGCTCAAAGCAAACTATAATTAAATAAAACAATAAAAATTTTAACTCAATGAATATCCTAGGAGTTA
ATCTGCTGTGGTAATCGATAGTGACATAAAAACAAGATGCATAGAGCTGAAAAAGGCATCTGTCCACCTGAGTGAATTCCTGTAGTAGGC
AGCATTTCAAGATTTAGTTTGATTCAAACCTGCTGATAAAACAAATGCTTATATGCAAGAAAAACTAGCAGCAAGATATGAATAAATCTC
CCCATTATGTTAAAAACTAATCAGCATGACACATTTATATTTAGGTATTTCTTCTGCAGAGGATTGCCAGAAATTTCTTAATGAGAGTGA
TAATTTGGTGATCCACCTATGTACCTTTTGATGTCTCATCACAGAGATTAGTGCTTCCTCTGATAATACATTTGCTTGATCCTGCTAATA
AGAACTCACCTTTCTTTTTAACGAAATCAATTTGTGTTAATTTACATAGGGAAAAACGTTCCTTGAGAGGGAGGAGAGGGGTGTTTACCA
CCCACAGGAGCAGTTCCATCCCTGGTTACCCACCAGTATCCCTGCCAGATGTTAGACTGGAATTAGAATGAAAATTTAAAAAAAAACGAA
ATAATAATCCACTAAATGGCCTTCTAATTAGAGAAATTTGAAGATTTCTATCAAATATAAAAAGTGAGAAATAGAAATCATTCCCTTTAA
TTTATGACAAATTAAAATTATTGAAGTAAAATGTTTCTAAGTCAGTTTCTGGATAGTTCTTGAATGAGTCAAGAAAAAACTCAAACACTA
AATTTCTAAGCTAATTTGTTCATTATTCCTTTCTGTTTATTATTTATTATATGAGTGCAAATTGCAAATGTATTAGAAAAGACAATATAG
CCTTCACATTCACAAGTGTGCCTTCTGGCCTTTGAAATCTTTTAACATAAGATCAATATAACATATTTGTTCCCCATAAAAATCTCTTAT
GTACAGGGAATAAGGTCCTCCATAGCTACACAGAGACACCCATTCTTGCAGTCTGGCATTCTTAACACCTTTAGCTTCAAAGGCAGTCGG
TTTCAATTTCAAGCTAAAATTGTGAATATACAATTAAGTGCGCAACTTGGGCCTTCAGACCAAATAATTAATGCTCCTCAAATTAAATAA
TGAGTGGCTGAAAAGCCTAATGTGTAACAACAGAGTAAGTGACTTCAACGGCTTCCTGAACCTTCATTTTGAGGGTGTTCTCATCTCACC
CACCTCTGGGCTAGGTATCCTCTGTTAATTGCTAACAATTTCCTACCAAAATAGTGCAATCAGGACTGCCCATCACAGCAAATTACTCCA
ATTAATGCCCTTTCCTCTTCTGTGAACCAAAAATATCTCTCTCCTGTCTCTCATCTCTATCCCAGGTATAAATTGACTAATAAATTTTAC
AGAGTTTTAGTCAAAATTATGAATTTTAATTTCCAGCAACATTATTCCTTTAGTCTTTCTATTCCCCAAAACATTCTTAAATTTTGGTAT
CAAATGTTCATTTCTGTCCTAGAGATTGTGGTTCCCATGGCTACAGATTTTTGTATAGTGGTAGTATGAGTGGAATAAGATCTGAGACTT
TTCCTGGTGATATCCACCATTCTCTTGTGAACTCATTGCAGAATAAACAGCCTCTTTCACTTTCATTGTAAGTAGTTCTTTAGGTTGGCA
AAGCAGGCACCAGAATCTGAATTTGAATGAAATCTGTACTTTCTTTTGTTGGCCTATTTTTTGCCAAGACAGCCTGCCTATTGTATATTT
AGGAATCAAATATTCATTTTTTCTGTTTGTAAAGCCAGAAATATTTCAGTTAAAAAGAATATAATTTTATATTATTTTAATAATTCTTTT
TAAGTAAAGTAGGAAAATTTCTGCCACCTGAGATGTTACTGTTTTTATTTATATGAAAATTCCATTTTTTTCTTTATGACTCTTTTCCCA
TACCATTATGATATGTTCAGCATTAGTATTTTCCATTTTACCACTAAACAAATAAGCCAGGACTAATAACAATAGCAGTTTGAGAGTTTT
TATTTTGGCATTTTGGTTTTAATTAGGAAAGAAAACATGGATGCTATTAAAACTAGTTGTAGTTAAAAATGTTTTGAATGAGGCTACTAA
CGCTATCTTAGTCATCTCAAAGAGAAAGAGAAGAAGTAAAATTTTAAATACCTTTTTGGCATTTTTAACCAATTCATATGAACAAAAACA
TATATTCTATTAAAGCAAAATAAAGAATAGTTTAAAACACTAGTCTTCTTGCATGTGAATATTTTCCCCCTAACAGACAAGATAGAATCC
ATTTCTGGACACTCTAAAAGAAAGTAATGTTAATTGAGAGAGCTGTCTCCAAATGGAACTCAACCTGACCAGAATCCCATCCGCAGGCAA
GAGATGGGCTGTGGGGCCGACCATAAGTTTTATTCTGAGACGAGATGCTTTATGGCTGCTGGCTGCATTATGGCATCTAGCAGTCCCCAC
TGGTTTGTGGGAACAAAACACATGGATTGATATTCAATATGAGTTTGGTAAGTTGGAGAAAAATGGAGACGATACGGAGTAGTCTAAAGG
CACAACAAATAAGAAGGTGCCAGAGGTAGGGAAGGGTCTGAGAGGGGTAGTTGCAGAAGCATTTAGCTTTCATAGATGAGGGGAGAGTTT
TTTGGTTTTATGAAGATTAGGCAGCCCTCCTGAGGAAAGTATTAAGGATAGAATGAGACACTTGTCTTGGTGGTTTGGTGAAGTCGTGTC
GAAGGCAAAAGGATGAACTACACATATTTTGAGCATGATTTAGTAATATTGTTTGCAAGTTGAGAAACAGAAATTCAGCCATTCTCCTGA
CTGATGGTAGGTGAAATTCTTCCCAATATTAGAGCCAATCTGGGTTACCATACGTTCATATATTTAACAGCTATTTGTTAAACAACTGTG
ATGTTCCAGGCACTGTTCTAGGTTCTTAGGATACACCATATAACAAAACAAATAGTGATCCTTGCCCTCATGTGCCAGCTCTGTGTTAAA
TGCTAACTATTATCTTATTCAATCCTCCAAATAACCCTATAGGATATATATCATTCCACAGACAAGGAAGCTGAGGGTTAAATGGGATAA
GAATCTTGCTCAAAGTCTCACTGGCTTTAAAATATTAATATATATTTTACATCATTCAAGACAGATATATAATTAGCTGAATATTCTCAC
CTCTATTAACTGAATGTAGAGTGTCAGGTACATGGGAAGTAAGTTATTTACGTGATCTGAAATAAGAGGACAACCTTTGCCAAATTACTT
TTATTACCATGGAGAAGAAAGCTTCAATGAAATGCCTGTTTCAGCCCATCTTCAGTATTGGTTGGTTAATACCATTTGTTAACACCAATC
CTTTCCTCTTTTACTGCTAACATGTGACTGTGTTTAAAATTATAGATTGCAGCAGAGTGTTGGCCAAGGATTATTGTAGTAGGATAAAGT
TTCCCTGTATTTGAAATTTACCCAAACTGTAGCAAATACATCTTTCCTTCTTTATGGAGGTCACACGTGTGCATAGTATGTGCCTGAATA
CAGGTAAACTTTGTGTTTTAAAATTACATGGCCTTTTTTAGAGTCGACTGAAGGCTAGACTCTTCTTGCCCATGTTGCTGGATAGGCTTT
CAAATCTCAGGCCTTGGAGAGTTAAATGACTTTCTGATATTTCTTACGGTGGAGCCACATAAGAAATACACACATTCCTAGTTTGAGCAA
TGGATGTGTATATTGGGGATCTTCACTTTTATGTATCTGGTAGTCATGATGGTGCCTATTCCCAACTGTAGGAAAGGAAAGCCCTCAAGG
AGAAAATTCTCTTTCAAAAAGGCTCAGATTTCTAACAATTATGTCTAAATGTTTCTTCAATTTAGAACATGTACAAAAGCTACTTAATAT
TAGCAGAGTAGTTCTTGTGTTTTCATTTCAAATGAAATATTCCCAGTTCCAAAGTTTATTTCCTTGGCATTTTCAAGAAGGATGGTTATT
TTTAGTTCTGGTTATTTGGTGTTGGAGGTCTGTGACACTTCCTTATACATTTAAAGCCCCCTTTGAATAGTTGTATCAATAGTTCAAAAG
CCTGTAGATATCTTGCTTTTCTATTCTGACAGCCCAGCTTCTGCAGACTCAGGCCAACCTTAGGTATGTCACATCAGTTCCCCATCTGTG
TAAATTACCTGAACCTCTCTGTGGTATTCACTGAGAGTTGAGCTTCTACTAAGGGATTTCCTTGACCTGGGCTTTTAACACCAGATTTGT
AGTGGAGTGTTTATTAGTAAAGCAAAGGAGTAAGTCAGAGATGCTAGCCCCTGCTCTCAGTTAAACAGAACTATCCTCCTTCCTGAATAT
TTAAACATAAAATTAATTTTAAACTACTATAAAAATCATGTTCCATTGCTTGCCAAATCTTATACCATTATAATGCTGTATTTTTACATG
TTAGTATACATTGTGTCCATAGGGATATAAATATGAGAATTTCAGCAACTGTCTTGCAGGGTTAAGATGTGCTATTTGTTGATTTTGCAA
ATTTTTCTCATGTGGTACAGTCCCTCCAAAGAAAATTTCCTTAGACCTAAATGGTAGCATAATAATTTCTCCTCCATATCCGTGACTAAC
AAGTTCCTGAAAACAGAAGTAGACATATTTTATGCCCAATTTAGTACCTAATAATTGAGGCTTAAAACAAAATTTTCTTGGGCAAGTTGG
GTGATTAAATATGAATTAAAACTTCTAGAGAAAGATTTCCAGATGCCCCTGTTTTCCATTTTGATTATGGTTTTAGTTTCATAGCAACTT
GGGGGAAAAAAATCATTTACTTTATGTCGTATTACAACAACAACTTTGACAGCTTAAATGTAGTGACCTCTCTGAAGGTAATATGCACAT
TATAATTTAGGATGAAAGCAGATTTAAACTAAGACTTTCTGAGATGAAATAAAAGTAACCAATTCATAATAGTCATGTTTATTGCAGCAA
TATCTTGGGAACTTAAGTTTAGTGGCGTTTGAGGTGTTTCTGACTATCTTGCTTGTTCATTTCACCCTGCTCTGCAGAGACAGAATATGA
TTGAATGAACTGCCCATTATATTAATGACCAGTTCAAAGCAGTTTTGTGCTTTGGCTATAGATAAAATTTGGCAAAAATACTGTAGGCCT
TTCTGGTCCATATTTATCCTTAAAGTATTTTTGCCAATCAATAAAAATGAAATATTTATCCAGAAATAGAAAAAGCTCTTTCCTATGACA
TTGACATAGAAGCCCAAATACTCCTTGTTTGAGACCCTGCATGTCTTTTGTGTTTAACTGAATCAATGATTTTTTTTAGTTGTGCTCTTA
ATTGCATTATTTCACATATGTAACACTGGGTTTGTTTTGGTTATATAGTATTATTTTACTTTATTCTAATTTCAACTCATGTCACTCTGT

>36572_36572_2_HK1-CTNNA3_HK1_chr10_71078766_ENST00000359426_CTNNA3_chr10_68535282_ENST00000433211_length(amino acids)=585AA_BP=39
MRRTDRPHACRPATPTASMIAAQLLAYYFTELKDDQVKKAGKKERSNTLNIALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLI
EAAKNGREKEIKEYAAIFHEHTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTMEMYKRTWENHI
HVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIP
EFVTQVNVALEALSKSSLNVLDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEHEVRSHTSIQTEGKTDRAKMTQLPEAEK
EKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPS
CKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPAGPRHPVVMWRM

--------------------------------------------------------------

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Fusion Gene PPI Analysis for HK1-CTNNA3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for HK1-CTNNA3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for HK1-CTNNA3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource