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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:HNRNPA2B1-DSP (FusionGDB2 ID:37069) |
Fusion Gene Summary for HNRNPA2B1-DSP |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: HNRNPA2B1-DSP | Fusion gene ID: 37069 | Hgene | Tgene | Gene symbol | HNRNPA2B1 | DSP | Gene ID | 3181 | 1834 |
| Gene name | heterogeneous nuclear ribonucleoprotein A2/B1 | dentin sialophosphoprotein | |
| Synonyms | HNRNPA2|HNRNPB1|HNRPA2|HNRPA2B1|HNRPB1|IBMPFD2|RNPA2|SNRPB1 | DFNA39|DGI1|DMP3|DPP|DSP | |
| Cytomap | 7p15.2 | 4q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | heterogeneous nuclear ribonucleoproteins A2/B1HNRNPA2B1/MYC fusionepididymis secretory sperm binding proteinhnRNP A2 / hnRNP B1nuclear ribonucleoprotein particle A2 protein | dentin sialophosphoproteindeafness, autosomal dominant 39dentin phosphophoryndentin phosphoproteindentin phosphoryndentin sialoprotein | |
| Modification date | 20200314 | 20200313 | |
| UniProtAcc | P22626 | P15924 | |
| Ensembl transtripts involved in fusion gene | ENST00000356674, ENST00000354667, ENST00000476233, | ENST00000379802, ENST00000418664, | |
| Fusion gene scores | * DoF score | 43 X 37 X 14=22274 | 22 X 19 X 10=4180 |
| # samples | 50 | 26 | |
| ** MAII score | log2(50/22274*10)=-5.47728875772656 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(26/4180*10)=-4.00691941393979 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: HNRNPA2B1 [Title/Abstract] AND DSP [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | HNRNPA2B1(26231467)-DSP(7575528), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | HNRNPA2B1 | GO:0006397 | mRNA processing | 2557628 |
| Hgene | HNRNPA2B1 | GO:0006406 | mRNA export from nucleus | 10567417 |
| Hgene | HNRNPA2B1 | GO:0031053 | primary miRNA processing | 26321680 |
| Hgene | HNRNPA2B1 | GO:0050658 | RNA transport | 17004321 |
| Hgene | HNRNPA2B1 | GO:1990428 | miRNA transport | 24356509 |
| Fusion gene breakpoints across HNRNPA2B1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across DSP (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LUSC | TCGA-22-0944-01A | HNRNPA2B1 | chr7 | 26231467 | - | DSP | chr6 | 7575528 | + |
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Fusion Gene ORF analysis for HNRNPA2B1-DSP |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000356674 | ENST00000379802 | HNRNPA2B1 | chr7 | 26231467 | - | DSP | chr6 | 7575528 | + |
| In-frame | ENST00000356674 | ENST00000418664 | HNRNPA2B1 | chr7 | 26231467 | - | DSP | chr6 | 7575528 | + |
| intron-3CDS | ENST00000354667 | ENST00000379802 | HNRNPA2B1 | chr7 | 26231467 | - | DSP | chr6 | 7575528 | + |
| intron-3CDS | ENST00000354667 | ENST00000418664 | HNRNPA2B1 | chr7 | 26231467 | - | DSP | chr6 | 7575528 | + |
| intron-3CDS | ENST00000476233 | ENST00000379802 | HNRNPA2B1 | chr7 | 26231467 | - | DSP | chr6 | 7575528 | + |
| intron-3CDS | ENST00000476233 | ENST00000418664 | HNRNPA2B1 | chr7 | 26231467 | - | DSP | chr6 | 7575528 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000356674 | HNRNPA2B1 | chr7 | 26231467 | - | ENST00000379802 | DSP | chr6 | 7575528 | + | 8730 | 1711 | 1726 | 7890 | 2054 |
| ENST00000356674 | HNRNPA2B1 | chr7 | 26231467 | - | ENST00000418664 | DSP | chr6 | 7575528 | + | 6788 | 1711 | 1726 | 6093 | 1455 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000356674 | ENST00000379802 | HNRNPA2B1 | chr7 | 26231467 | - | DSP | chr6 | 7575528 | + | 0.006403545 | 0.99359643 |
| ENST00000356674 | ENST00000418664 | HNRNPA2B1 | chr7 | 26231467 | - | DSP | chr6 | 7575528 | + | 0.00316687 | 0.99683315 |
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Fusion Genomic Features for HNRNPA2B1-DSP |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| HNRNPA2B1 | chr7 | 26231463 | - | DSP | chr6 | 7575527 | + | 4.69E-07 | 0.9999995 |
| HNRNPA2B1 | chr7 | 26231463 | - | DSP | chr6 | 7575527 | + | 4.69E-07 | 0.9999995 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for HNRNPA2B1-DSP |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:26231467/chr6:7575528) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| HNRNPA2B1 | DSP |
| FUNCTION: Heterogeneous nuclear ribonucleoprotein (hnRNP) that associates with nascent pre-mRNAs, packaging them into hnRNP particles. The hnRNP particle arrangement on nascent hnRNA is non-random and sequence-dependent and serves to condense and stabilize the transcripts and minimize tangling and knotting. Packaging plays a role in various processes such as transcription, pre-mRNA processing, RNA nuclear export, subcellular location, mRNA translation and stability of mature mRNAs (PubMed:19099192). Forms hnRNP particles with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus. Involved in transport of specific mRNAs to the cytoplasm in oligodendrocytes and neurons: acts by specifically recognizing and binding the A2RE (21 nucleotide hnRNP A2 response element) or the A2RE11 (derivative 11 nucleotide oligonucleotide) sequence motifs present on some mRNAs, and promotes their transport to the cytoplasm (PubMed:10567417). Specifically binds single-stranded telomeric DNA sequences, protecting telomeric DNA repeat against endonuclease digestion (By similarity). Also binds other RNA molecules, such as primary miRNA (pri-miRNAs): acts as a nuclear 'reader' of the N6-methyladenosine (m6A) mark by specifically recognizing and binding a subset of nuclear m6A-containing pri-miRNAs. Binding to m6A-containing pri-miRNAs promotes pri-miRNA processing by enhancing binding of DGCR8 to pri-miRNA transcripts (PubMed:26321680). Involved in miRNA sorting into exosomes following sumoylation, possibly by binding (m6A)-containing pre-miRNAs (PubMed:24356509). Acts as a regulator of efficiency of mRNA splicing, possibly by binding to m6A-containing pre-mRNAs (PubMed:26321680). Plays also a role in the activation of the innate immune response (PubMed:31320558). Mechanistically, senses the presence of viral DNA in the nucleus, homodimerizes and is demethylated by JMJD6 (PubMed:31320558). In turn, translocates to the cytoplasm where it activates the TBK1-IRF3 pathway, leading to interferon alpha/beta production (PubMed:31320558). {ECO:0000250|UniProtKB:A7VJC2, ECO:0000269|PubMed:10567417, ECO:0000269|PubMed:24356509, ECO:0000269|PubMed:26321680, ECO:0000303|PubMed:19099192}.; FUNCTION: (Microbial infection) Involved in the transport of HIV-1 genomic RNA out of the nucleus, to the microtubule organizing center (MTOC), and then from the MTOC to the cytoplasm: acts by specifically recognizing and binding the A2RE (21 nucleotide hnRNP A2 response element) sequence motifs present on HIV-1 genomic RNA, and promotes its transport. {ECO:0000269|PubMed:15294897, ECO:0000269|PubMed:17004321}. | FUNCTION: Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | HNRNPA2B1 | chr7:26231467 | chr6:7575528 | ENST00000356674 | - | 11 | 11 | 202_353 | 514 | 439.3333333333333 | Compositional bias | Note=Gly-rich |
| Hgene | HNRNPA2B1 | chr7:26231467 | chr6:7575528 | ENST00000356674 | - | 11 | 11 | 112_191 | 514 | 439.3333333333333 | Domain | RRM 2 |
| Hgene | HNRNPA2B1 | chr7:26231467 | chr6:7575528 | ENST00000356674 | - | 11 | 11 | 21_104 | 514 | 439.3333333333333 | Domain | RRM 1 |
| Hgene | HNRNPA2B1 | chr7:26231467 | chr6:7575528 | ENST00000356674 | - | 11 | 11 | 9_15 | 514 | 439.3333333333333 | Motif | Nuclear localization signal |
| Hgene | HNRNPA2B1 | chr7:26231467 | chr6:7575528 | ENST00000356674 | - | 11 | 11 | 193_353 | 514 | 439.3333333333333 | Region | Low complexity (LC) region |
| Hgene | HNRNPA2B1 | chr7:26231467 | chr6:7575528 | ENST00000356674 | - | 11 | 11 | 308_347 | 514 | 439.3333333333333 | Region | Nuclear targeting sequence |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 1018_1945 | 812 | 2872.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 1018_1945 | 812 | 2273.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 1057_1945 | 812 | 2872.0 | Region | Note=Central fibrous rod domain | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 1946_2871 | 812 | 2872.0 | Region | Note=Globular 2 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 1960_2208 | 812 | 2872.0 | Region | Note=4.5 X 38 AA tandem repeats (Domain A) | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2244_2446 | 812 | 2872.0 | Region | Note=4.5 X 38 AA tandem repeats (Domain B) | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2609_2822 | 812 | 2872.0 | Region | Note=4.5 X 38 AA tandem repeats (Domain C) | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2824_2847 | 812 | 2872.0 | Region | Note=6 X 4 AA tandem repeats of G-S-R-[SR] | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 1057_1945 | 812 | 2273.0 | Region | Note=Central fibrous rod domain | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 1946_2871 | 812 | 2273.0 | Region | Note=Globular 2 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 1960_2208 | 812 | 2273.0 | Region | Note=4.5 X 38 AA tandem repeats (Domain A) | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2244_2446 | 812 | 2273.0 | Region | Note=4.5 X 38 AA tandem repeats (Domain B) | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2609_2822 | 812 | 2273.0 | Region | Note=4.5 X 38 AA tandem repeats (Domain C) | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2824_2847 | 812 | 2273.0 | Region | Note=6 X 4 AA tandem repeats of G-S-R-[SR] | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2009_2045 | 812 | 2872.0 | Repeat | Note=Plectin 1 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2046_2083 | 812 | 2872.0 | Repeat | Note=Plectin 2 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2084_2121 | 812 | 2872.0 | Repeat | Note=Plectin 3 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2122_2159 | 812 | 2872.0 | Repeat | Note=Plectin 4 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2163_2197 | 812 | 2872.0 | Repeat | Note=Plectin 5 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2198_2233 | 812 | 2872.0 | Repeat | Note=Plectin 6 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2251_2288 | 812 | 2872.0 | Repeat | Note=Plectin 7 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2289_2326 | 812 | 2872.0 | Repeat | Note=Plectin 8 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2327_2364 | 812 | 2872.0 | Repeat | Note=Plectin 9 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2365_2402 | 812 | 2872.0 | Repeat | Note=Plectin 10 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2406_2440 | 812 | 2872.0 | Repeat | Note=Plectin 11 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2456_2493 | 812 | 2872.0 | Repeat | Note=Plectin 12 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2507_2544 | 812 | 2872.0 | Repeat | Note=Plectin 13 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2610_2647 | 812 | 2872.0 | Repeat | Note=Plectin 14 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2648_2685 | 812 | 2872.0 | Repeat | Note=Plectin 15 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2724_2761 | 812 | 2872.0 | Repeat | Note=Plectin 16 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 2762_2799 | 812 | 2872.0 | Repeat | Note=Plectin 17 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2009_2045 | 812 | 2273.0 | Repeat | Note=Plectin 1 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2046_2083 | 812 | 2273.0 | Repeat | Note=Plectin 2 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2084_2121 | 812 | 2273.0 | Repeat | Note=Plectin 3 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2122_2159 | 812 | 2273.0 | Repeat | Note=Plectin 4 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2163_2197 | 812 | 2273.0 | Repeat | Note=Plectin 5 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2198_2233 | 812 | 2273.0 | Repeat | Note=Plectin 6 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2251_2288 | 812 | 2273.0 | Repeat | Note=Plectin 7 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2289_2326 | 812 | 2273.0 | Repeat | Note=Plectin 8 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2327_2364 | 812 | 2273.0 | Repeat | Note=Plectin 9 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2365_2402 | 812 | 2273.0 | Repeat | Note=Plectin 10 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2406_2440 | 812 | 2273.0 | Repeat | Note=Plectin 11 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2456_2493 | 812 | 2273.0 | Repeat | Note=Plectin 12 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2507_2544 | 812 | 2273.0 | Repeat | Note=Plectin 13 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2610_2647 | 812 | 2273.0 | Repeat | Note=Plectin 14 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2648_2685 | 812 | 2273.0 | Repeat | Note=Plectin 15 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2724_2761 | 812 | 2273.0 | Repeat | Note=Plectin 16 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 2762_2799 | 812 | 2273.0 | Repeat | Note=Plectin 17 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | HNRNPA2B1 | chr7:26231467 | chr6:7575528 | ENST00000354667 | - | 1 | 12 | 202_353 | 0 | 1115.3333333333333 | Compositional bias | Note=Gly-rich |
| Hgene | HNRNPA2B1 | chr7:26231467 | chr6:7575528 | ENST00000354667 | - | 1 | 12 | 112_191 | 0 | 1115.3333333333333 | Domain | RRM 2 |
| Hgene | HNRNPA2B1 | chr7:26231467 | chr6:7575528 | ENST00000354667 | - | 1 | 12 | 21_104 | 0 | 1115.3333333333333 | Domain | RRM 1 |
| Hgene | HNRNPA2B1 | chr7:26231467 | chr6:7575528 | ENST00000354667 | - | 1 | 12 | 9_15 | 0 | 1115.3333333333333 | Motif | Nuclear localization signal |
| Hgene | HNRNPA2B1 | chr7:26231467 | chr6:7575528 | ENST00000354667 | - | 1 | 12 | 193_353 | 0 | 1115.3333333333333 | Region | Low complexity (LC) region |
| Hgene | HNRNPA2B1 | chr7:26231467 | chr6:7575528 | ENST00000354667 | - | 1 | 12 | 308_347 | 0 | 1115.3333333333333 | Region | Nuclear targeting sequence |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 458_515 | 812 | 2872.0 | Domain | SH3 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 458_515 | 812 | 2273.0 | Domain | SH3 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 1_1056 | 812 | 2872.0 | Region | Note=Globular 1 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 1_1056 | 812 | 2273.0 | Region | Note=Globular 1 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 178_271 | 812 | 2872.0 | Repeat | Note=Spectrin 1 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 272_375 | 812 | 2872.0 | Repeat | Note=Spectrin 2 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 376_446 | 812 | 2872.0 | Repeat | Note=Spectrin 3a | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 516_545 | 812 | 2872.0 | Repeat | Note=Spectrin 3b | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 546_627 | 812 | 2872.0 | Repeat | Note=Spectrin 4 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 654_769 | 812 | 2872.0 | Repeat | Note=Spectrin 5 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 770_883 | 812 | 2872.0 | Repeat | Note=Spectrin 6 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 178_271 | 812 | 2273.0 | Repeat | Note=Spectrin 1 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 272_375 | 812 | 2273.0 | Repeat | Note=Spectrin 2 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 376_446 | 812 | 2273.0 | Repeat | Note=Spectrin 3a | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 516_545 | 812 | 2273.0 | Repeat | Note=Spectrin 3b | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 546_627 | 812 | 2273.0 | Repeat | Note=Spectrin 4 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 654_769 | 812 | 2273.0 | Repeat | Note=Spectrin 5 | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 770_883 | 812 | 2273.0 | Repeat | Note=Spectrin 6 |
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Fusion Gene Sequence for HNRNPA2B1-DSP |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >37069_37069_1_HNRNPA2B1-DSP_HNRNPA2B1_chr7_26231467_ENST00000356674_DSP_chr6_7575528_ENST00000379802_length(transcript)=8730nt_BP=1711nt AGTAGCAGCAGCGCCGGGTCCCGTGCGGAGGTGCTCCTCGCAGAGTTGTTTCTCGAGCAGCGGCAGTTCTCACTACAGCGCCAGGACGAG TCCGGTTCGTGTTCGTCCGCGGAGATCTCTCTCATCTCGCTCGGCTGCGGGAAATCGGGCTGAAGCGACTGAGTCCGCGATGGAGAGAGA AAAGGAACAGTTCCGTAAGCTCTTTATTGGTGGCTTAAGCTTTGAAACCACAGAAGAAAGTTTGAGGAACTACTACGAACAATGGGGAAA GCTTACAGACTGTGTGGTAATGAGGGATCCTGCAAGCAAAAGATCAAGAGGATTTGGTTTTGTAACTTTTTCATCCATGGCTGAGGTTGA TGCTGCCATGGCTGCAAGACCTCATTCAATTGATGGGAGAGTAGTTGAGCCAAAACGTGCTGTAGCAAGAGAGGAATCTGGAAAACCAGG GGCTCATGTAACTGTGAAGAAGCTGTTTGTTGGCGGAATTAAAGAAGATACTGAGGAACATCACCTTAGAGATTACTTTGAGGAATATGG AAAAATTGATACCATTGAGATAATTACTGATAGGCAGTCTGGAAAGAAAAGAGGCTTTGGCTTTGTTACTTTTGATGACCATGATCCTGT GGATAAAATCGTATTGCAGAAATACCATACCATCAATGGTCATAATGCAGAAGTAAGAAAGGCTTTGTCTAGACAAGAAATGCAGGAAGT TCAGAGTTCTAGGAGTGGAAGAGGAGGCAACTTTGGCTTTGGGGATTCACGTGGTGGCGGTGGAAATTTCGGACCAGGACCAGGAAGTAA CTTTAGAGGAGGATCTGATGGATATGGCAGTGGACGTGGATTTGGGGATGGCTATAATGGGTATGGAGGAGGACCTGGAGGTGGCAATTT TGGAGGTAGCCCCGGTTATGGAGGAGGAAGAGGAGGATATGGTGGTGGAGGACCTGGATATGGCAACCAGGGTGGGGGCTACGGAGGTGG TTATGACAACTATGGAGGAGGAAATTATGGAAGTGGAAATTACAATGATTTTGGAAATTATAACCAGCAACCTTCTAACTACGGTCCAAT GAAGAGTGGAAACTTTGGTGGTAGCAGGAACATGGGGGGACCATATGGTGGAGGAAACTATGGTCCAGGAGGCAGTGGAGGAAGTGGGGG TTATGGTGGGAGGAGCCGATACTGAGCTTCTTCCTATTTGCCATGGGCTTCACTGTATAAATAGGAGAGGATGAGAGCCCAGAGGTAACA GAACAGCTTCAGGTTATCGAAATAACAATGTTAAGGAAACTCTTATCTCAGTCATGCATAAATATGCAGTGATATGGCAGAAGACACCAG AGCAGATGCAGAGAGCCATTTTGTGAATGGATTGGATTATTTAATAACATTACCTTACTGTGGAGGAAGGATTGTAAAAAAAAATGCCTT TGAGACAGTTTCTTAGCTTTTTAATTGTTGTTTCTTTCTAGTGGTCTTTGTAAGAGTGTAGAAGCATTCCTTCTTTGATAATGTTAAATT TGTAAGTTTCAGGTGACATGTGAAACCTTTTTTAAGATTTTTCTCAAAGTTTTGAAAAGCTATTAGCCAGGATCATGGTGTAATAAGACA TAACGTTTTTCCTTTAAAAAAATTTAAGTGCGTGTGTAGAGTTAAGAAGCTGTTGTACATTTATGATTTAATAAAATAATTCTAAAGGAA AAAAATAAAAAATGACTTGAACTTGAAGAAGTCGTTGTTGGCCACTATGAAGACAGAACTACAGAAAGCCCAGCAGATCCACTCTCAGAC TTCACAGCAGTATCCACTTTATGATCTGGACTTGGGCAAGTTCGGTGAAAAAGTCACACAGCTGACAGACCGCTGGCAAAGGATAGATAA ACAGATCGACTTTAGGTTATGGGACCTGGAGAAACAAATCAAGCAATTGAGGAATTATCGTGATAACTATCAGGCTTTCTGCAAGTGGCT CTATGATGCTAAACGCCGCCAGGATTCCTTAGAATCCATGAAATTTGGAGATTCCAACACAGTCATGCGGTTTTTGAATGAGCAGAAGAA CTTGCACAGTGAAATATCTGGCAAACGAGACAAATCAGAGGAAGTACAAAAAATTGCTGAACTTTGCGCCAATTCAATTAAGGATTATGA GCTCCAGCTGGCCTCATACACCTCAGGACTGGAAACTCTGCTGAACATACCTATCAAGAGGACCATGATTCAGTCCCCTTCTGGGGTGAT TCTGCAAGAGGCTGCAGATGTTCATGCTCGGTACATTGAACTACTTACAAGATCTGGAGACTATTACAGGTTCTTAAGTGAGATGCTGAA GAGTTTGGAAGATCTGAAGCTGAAAAATACCAAGATCGAAGTTTTGGAAGAGGAGCTCAGACTGGCCCGAGATGCCAACTCGGAAAACTG TAATAAGAACAAATTCCTGGATCAGAACCTGCAGAAATACCAGGCAGAGTGTTCCCAGTTCAAAGCGAAGCTTGCGAGCCTGGAGGAGCT GAAGAGACAGGCTGAGCTGGATGGGAAGTCGGCTAAGCAAAATCTAGACAAGTGCTACGGCCAAATAAAAGAACTCAATGAGAAGATCAC CCGACTGACTTATGAGATTGAAGATGAAAAGAGAAGAAGAAAATCTGTGGAAGACAGATTTGACCAACAGAAGAATGACTATGACCAACT GCAGAAAGCAAGGCAATGTGAAAAGGAGAACCTTGGTTGGCAGAAATTAGAGTCTGAGAAAGCCATCAAGGAGAAGGAGTACGAGATTGA AAGGTTGAGGGTTCTACTGCAGGAAGAAGGCACCCGGAAGAGAGAATATGAAAATGAGCTGGCAAAGGTAAGAAACCACTATAATGAGGA GATGAGTAATTTAAGGAACAAGTATGAAACAGAGATTAACATTACGAAGACCACCATCAAGGAGATATCCATGCAAAAAGAGGATGATTC CAAAAATCTTAGAAACCAGCTTGATAGACTTTCAAGGGAAAATCGAGATCTGAAGGATGAAATTGTCAGGCTCAATGACAGCATCTTGCA GGCCACTGAGCAGCGAAGGCGAGCTGAAGAAAACGCCCTTCAGCAAAAGGCCTGTGGCTCTGAGATAATGCAGAAGAAGCAGCATCTGGA GATAGAACTGAAGCAGGTCATGCAGCAGCGCTCTGAGGACAATGCCCGGCACAAGCAGTCCCTGGAGGAGGCTGCCAAGACCATTCAGGA CAAAAATAAGGAGATCGAGAGACTCAAAGCTGAGTTTCAGGAGGAGGCCAAGCGCCGCTGGGAATATGAAAATGAACTGAGTAAGGTAAG AAACAATTATGATGAGGAGATCATTAGCTTAAAAAATCAGTTTGAGACCGAGATCAACATCACCAAGACCACCATCCACCAGCTCACCAT GCAGAAGGAAGAGGATACCAGTGGCTACCGGGCTCAGATAGACAATCTCACCCGAGAAAACAGGAGCTTATCTGAAGAAATAAAGAGGCT GAAGAACACTCTAACCCAGACCACAGAGAATCTCAGGAGGGTGGAAGAAGACATCCAACAGCAAAAGGCCACTGGCTCTGAGGTGTCTCA GAGGAAACAGCAGCTGGAGGTTGAGCTGAGACAAGTCACTCAGATGCGAACAGAGGAGAGCGTAAGATATAAGCAATCTCTTGATGATGC TGCCAAAACCATCCAGGATAAAAACAAGGAGATAGAAAGGTTAAAACAACTGATCGACAAAGAAACAAATGACCGGAAATGCCTGGAAGA TGAAAACGCGAGATTACAAAGGGTCCAGTATGACCTGCAGAAAGCAAACAGTAGTGCGACGGAGACAATAAACAAACTGAAGGTTCAGGA GCAAGAACTGACACGCCTGAGGATCGACTATGAAAGGGTTTCCCAGGAGAGGACTGTGAAGGACCAGGATATCACGCGGTTCCAGAACTC TCTGAAAGAGCTGCAGCTGCAGAAGCAGAAGGTGGAAGAGGAGCTGAATCGGCTGAAGAGGACCGCGTCAGAAGACTCCTGCAAGAGGAA GAAGCTGGAGGAAGAGCTGGAAGGCATGAGGAGGTCGCTGAAGGAGCAAGCCATCAAAATCACCAACCTGACCCAGCAGCTGGAGCAGGC ATCCATTGTTAAGAAGAGGAGTGAGGATGACCTCCGGCAGCAGAGGGACGTGCTGGATGGCCACCTGAGGGAAAAGCAGAGGACCCAGGA AGAGCTGAGGAGGCTCTCTTCTGAGGTCGAGGCCCTGAGGCGGCAGTTACTCCAGGAACAGGAAAGTGTCAAACAAGCTCACTTGAGGAA TGAGCATTTCCAGAAGGCGATAGAAGATAAAAGCAGAAGCTTAAATGAAAGCAAAATAGAAATTGAGAGGCTGCAGTCTCTCACAGAGAA CCTGACCAAGGAGCACTTGATGTTAGAAGAAGAACTGCGGAACCTGAGGCTGGAGTACGATGACCTGAGGAGAGGACGAAGCGAAGCGGA CAGTGATAAAAATGCAACCATCTTGGAACTAAGGAGCCAGCTGCAGATCAGCAACAACCGGACCCTGGAACTGCAGGGGCTGATTAATGA TTTACAGAGAGAGAGGGAAAATTTGAGACAGGAAATTGAGAAATTCCAAAAGCAGGCTTTAGAGGCATCTAATAGGATTCAGGAATCAAA GAATCAGTGTACTCAGGTGGTACAGGAAAGAGAGAGCCTTCTGGTGAAAATCAAAGTCCTGGAGCAAGACAAGGCAAGGCTGCAGAGGCT GGAGGATGAGCTGAATCGTGCAAAATCAACTCTAGAGGCAGAAACCAGGGTGAAACAGCGCCTGGAGTGTGAGAAACAGCAAATTCAGAA TGACCTGAATCAGTGGAAGACTCAATATTCCCGCAAGGAGGAGGCTATTAGGAAGATAGAATCGGAAAGAGAAAAGAGTGAGAGAGAGAA GAACAGTCTTAGGAGTGAGATCGAAAGACTCCAAGCAGAGATCAAGAGAATTGAAGAGAGGTGCAGGCGTAAGCTGGAGGATTCTACCAG GGAGACACAGTCACAGTTAGAAACAGAACGCTCCCGATATCAGAGGGAGATTGATAAACTCAGACAGCGCCCATATGGGTCCCATCGAGA GACCCAGACTGAGTGTGAGTGGACCGTTGACACCTCCAAGCTGGTGTTTGATGGGCTGAGGAAGAAGGTGACAGCAATGCAGCTCTATGA GTGTCAGCTGATCGACAAAACAACCTTGGACAAACTATTGAAGGGGAAGAAGTCAGTGGAAGAAGTTGCTTCTGAAATCCAGCCATTCCT TCGGGGTGCAGGATCTATCGCTGGAGCATCTGCTTCTCCTAAGGAAAAATACTCTTTGGTAGAGGCCAAGAGAAAGAAATTAATCAGCCC AGAATCCACAGTCATGCTTCTGGAGGCCCAGGCAGCTACAGGTGGTATAATTGATCCCCATCGGAATGAGAAGCTGACTGTCGACAGTGC CATAGCTCGGGACCTCATTGACTTCGATGACCGTCAGCAGATATATGCAGCAGAAAAAGCTATCACTGGTTTTGATGATCCATTTTCAGG CAAGACAGTATCTGTTTCAGAAGCCATCAAGAAAAATTTGATTGATAGAGAAACCGGAATGCGCCTGCTGGAAGCCCAGATTGCTTCAGG GGGTGTAGTAGACCCTGTGAACAGTGTCTTTTTGCCAAAAGATGTCGCCTTGGCCCGGGGGCTGATTGATAGAGATTTGTATCGATCCCT GAATGATCCCCGAGATAGTCAGAAAAACTTTGTGGATCCAGTCACCAAAAAGAAGGTCAGTTACGTGCAGCTGAAGGAACGGTGCAGAAT CGAACCACATACTGGTCTGCTCTTGCTTTCAGTACAGAAGAGAAGCATGTCCTTCCAAGGAATCAGACAACCTGTGACCGTCACTGAGCT AGTAGATTCTGGTATATTGAGACCGTCCACTGTCAATGAACTGGAATCTGGTCAGATTTCTTATGACGAGGTTGGTGAGAGAATTAAGGA CTTCCTCCAGGGTTCAAGCTGCATAGCAGGCATATACAATGAGACCACAAAACAGAAGCTTGGCATTTATGAGGCCATGAAAATTGGCTT AGTCCGACCTGGTACTGCTCTGGAGTTGCTGGAAGCCCAAGCAGCTACTGGCTTTATAGTGGATCCTGTTAGCAACTTGAGGTTACCAGT GGAGGAAGCCTACAAGAGAGGTCTGGTGGGCATTGAGTTCAAAGAGAAGCTCCTGTCTGCAGAACGAGCTGTCACTGGGTATAATGATCC TGAAACAGGAAACATCATCTCTTTGTTCCAAGCCATGAATAAGGAACTCATCGAAAAGGGCCACGGTATTCGCTTATTAGAAGCACAGAT CGCAACCGGGGGGATCATTGACCCAAAGGAGAGCCATCGTTTACCAGTTGACATAGCATATAAGAGGGGCTATTTCAATGAGGAACTCAG TGAGATTCTCTCAGATCCAAGTGATGATACCAAAGGATTTTTTGACCCCAACACTGAAGAAAATCTTACCTATCTGCAACTAAAAGAAAG ATGCATTAAGGATGAGGAAACAGGGCTCTGTCTTCTGCCTCTGAAAGAAAAGAAGAAACAGGTGCAGACATCACAAAAGAATACCCTCAG GAAGCGTAGAGTGGTCATAGTTGACCCAGAAACCAATAAAGAAATGTCTGTTCAGGAGGCCTACAAGAAGGGCCTAATTGATTATGAAAC CTTCAAAGAACTGTGTGAGCAGGAATGTGAATGGGAAGAAATAACCATCACGGGATCAGATGGCTCCACCAGGGTGGTCCTGGTAGATAG AAAGACAGGCAGTCAGTATGATATTCAAGATGCTATTGACAAGGGCCTTGTTGACAGGAAGTTCTTTGATCAGTACCGATCCGGCAGCCT CAGCCTCACTCAATTTGCTGACATGATCTCCTTGAAAAATGGTGTCGGCACCAGCAGCAGCATGGGCAGTGGTGTCAGCGATGATGTTTT TAGCAGCTCCCGACATGAATCAGTAAGTAAGATTTCCACCATATCCAGCGTCAGGAATTTAACCATAAGGAGCAGCTCTTTTTCAGACAC CCTGGAAGAATCGAGCCCCATTGCAGCCATCTTTGACACAGAAAACCTGGAGAAAATCTCCATTACAGAAGGTATAGAGCGGGGCATCGT TGACAGCATCACGGGTCAGAGGCTTCTGGAGGCTCAGGCCTGCACAGGTGGCATCATCCACCCAACCACGGGCCAGAAGCTGTCACTTCA GGACGCAGTCTCCCAGGGTGTGATTGACCAAGACATGGCCACCAGGCTGAAGCCTGCTCAGAAAGCCTTCATAGGCTTCGAGGGTGTGAA GGGAAAGAAGAAGATGTCAGCAGCAGAGGCAGTGAAAGAAAAATGGCTCCCGTATGAGGCTGGCCAGCGCTTCCTGGAGTTCCAGTACCT CACGGGAGGTCTTGTTGACCCGGAAGTGCATGGGAGGATAAGCACCGAAGAAGCCATCCGGAAGGGGTTCATAGATGGCCGCGCCGCACA GAGGCTGCAAGACACCAGCAGCTATGCCAAAATCCTGACCTGCCCCAAAACCAAATTAAAAATATCCTATAAGGATGCCATAAATCGCTC CATGGTAGAAGATATCACTGGGCTGCGCCTTCTGGAAGCCGCCTCCGTGTCGTCCAAGGGCTTACCCAGCCCTTACAACATGTCTTCGGC TCCGGGGTCCCGCTCCGGCTCCCGCTCGGGATCTCGCTCCGGATCTCGCTCCGGGTCCCGCAGTGGGTCCCGGAGAGGAAGCTTTGACGC CACAGGGAATTCTTCCTACTCTTATTCCTACTCATTTAGCAGTAGTTCTATTGGGCACTAGTAGTCAGTTGGGAGTGGTTGCTATACCTT GACTTCATTTATATGAATTTCCACTTTATTAAATAATAGAAAAGAAAATCCCGGTGCTTGCAGTAGAGTGATAGGACATTCTATGCTTAC AGAAAATATAGCCATGATTGAAATCAAATAGTAAAGGCTGTTCTGGCTTTTTATCTTCTTAGCTCATCTTAAATAAGCAGTACACTTGGA TGCAGTGCGTCTGAAGTGCTAATCAGTTGTAACAATAGCACAAATCGAACTTAGGATTTGTTTCTTCTCTTCTGTGTTTCGATTTTTGAT CAATTCTTTAATTTTGGAAGCCTATAATACAGTTTTCTATTCTTGGAGATAAAAATTAAATGGATCACTGATATTTTAGTCATTCTGCTT CTCATCTAAATATTTCCATATTCTGTATTAGGAGAAAATTACCCTCCCAGCACCAGCCCCCCTCTCAAACCCCCAACCCAAAACCAAGCA TTTTGGAATGAGTCTCCTTTAGTTTCAGAGTGTGGATTGTATAACCCATATACTCTTCGATGTACTTGTTTGGTTTGGTATTAATTTGAC TGTGCATGACAGCGGCAATCTTTTCTTTGGTCAAAGTTTTCTGTTTATTTTGCTTGTCATATTCGATGTACTTTAAGGTGTCTTTATGAA GTTTGCTATTCTGGCAATAAACTTTTAGACTTTTGAAGTGTTTGTGTTTTAATTTAATATGTTTATAAGCATGTATAAACATTTAGCATA TTTTTATCATAGGTCTAAAAATATTTGTTTACTAAATACCTGTGAAGAAATACCATTAAAAAACTATTTGGTTCTGAATTCTTACTAGAA >37069_37069_1_HNRNPA2B1-DSP_HNRNPA2B1_chr7_26231467_ENST00000356674_DSP_chr6_7575528_ENST00000379802_length(amino acids)=2054AA_BP= MNLKKSLLATMKTELQKAQQIHSQTSQQYPLYDLDLGKFGEKVTQLTDRWQRIDKQIDFRLWDLEKQIKQLRNYRDNYQAFCKWLYDAKR RQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAELCANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAA DVHARYIELLTRSGDYYRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLEELKRQAE LDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVL LQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQR RRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDE EIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQL EVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTR LRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKK RSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEH LMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQ VVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRS EIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQLYECQLID KTTLDKLLKGKKSVEEVASEIQPFLRGAGSIAGASASPKEKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDL IDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRD SQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKDFLQGS SCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNI ISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDE ETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQ YDIQDAIDKGLVDRKFFDQYRSGSLSLTQFADMISLKNGVGTSSSMGSGVSDDVFSSSRHESVSKISTISSVRNLTIRSSSFSDTLEESS PIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKM SAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDI -------------------------------------------------------------- >37069_37069_2_HNRNPA2B1-DSP_HNRNPA2B1_chr7_26231467_ENST00000356674_DSP_chr6_7575528_ENST00000418664_length(transcript)=6788nt_BP=1711nt AGTAGCAGCAGCGCCGGGTCCCGTGCGGAGGTGCTCCTCGCAGAGTTGTTTCTCGAGCAGCGGCAGTTCTCACTACAGCGCCAGGACGAG TCCGGTTCGTGTTCGTCCGCGGAGATCTCTCTCATCTCGCTCGGCTGCGGGAAATCGGGCTGAAGCGACTGAGTCCGCGATGGAGAGAGA AAAGGAACAGTTCCGTAAGCTCTTTATTGGTGGCTTAAGCTTTGAAACCACAGAAGAAAGTTTGAGGAACTACTACGAACAATGGGGAAA GCTTACAGACTGTGTGGTAATGAGGGATCCTGCAAGCAAAAGATCAAGAGGATTTGGTTTTGTAACTTTTTCATCCATGGCTGAGGTTGA TGCTGCCATGGCTGCAAGACCTCATTCAATTGATGGGAGAGTAGTTGAGCCAAAACGTGCTGTAGCAAGAGAGGAATCTGGAAAACCAGG GGCTCATGTAACTGTGAAGAAGCTGTTTGTTGGCGGAATTAAAGAAGATACTGAGGAACATCACCTTAGAGATTACTTTGAGGAATATGG AAAAATTGATACCATTGAGATAATTACTGATAGGCAGTCTGGAAAGAAAAGAGGCTTTGGCTTTGTTACTTTTGATGACCATGATCCTGT GGATAAAATCGTATTGCAGAAATACCATACCATCAATGGTCATAATGCAGAAGTAAGAAAGGCTTTGTCTAGACAAGAAATGCAGGAAGT TCAGAGTTCTAGGAGTGGAAGAGGAGGCAACTTTGGCTTTGGGGATTCACGTGGTGGCGGTGGAAATTTCGGACCAGGACCAGGAAGTAA CTTTAGAGGAGGATCTGATGGATATGGCAGTGGACGTGGATTTGGGGATGGCTATAATGGGTATGGAGGAGGACCTGGAGGTGGCAATTT TGGAGGTAGCCCCGGTTATGGAGGAGGAAGAGGAGGATATGGTGGTGGAGGACCTGGATATGGCAACCAGGGTGGGGGCTACGGAGGTGG TTATGACAACTATGGAGGAGGAAATTATGGAAGTGGAAATTACAATGATTTTGGAAATTATAACCAGCAACCTTCTAACTACGGTCCAAT GAAGAGTGGAAACTTTGGTGGTAGCAGGAACATGGGGGGACCATATGGTGGAGGAAACTATGGTCCAGGAGGCAGTGGAGGAAGTGGGGG TTATGGTGGGAGGAGCCGATACTGAGCTTCTTCCTATTTGCCATGGGCTTCACTGTATAAATAGGAGAGGATGAGAGCCCAGAGGTAACA GAACAGCTTCAGGTTATCGAAATAACAATGTTAAGGAAACTCTTATCTCAGTCATGCATAAATATGCAGTGATATGGCAGAAGACACCAG AGCAGATGCAGAGAGCCATTTTGTGAATGGATTGGATTATTTAATAACATTACCTTACTGTGGAGGAAGGATTGTAAAAAAAAATGCCTT TGAGACAGTTTCTTAGCTTTTTAATTGTTGTTTCTTTCTAGTGGTCTTTGTAAGAGTGTAGAAGCATTCCTTCTTTGATAATGTTAAATT TGTAAGTTTCAGGTGACATGTGAAACCTTTTTTAAGATTTTTCTCAAAGTTTTGAAAAGCTATTAGCCAGGATCATGGTGTAATAAGACA TAACGTTTTTCCTTTAAAAAAATTTAAGTGCGTGTGTAGAGTTAAGAAGCTGTTGTACATTTATGATTTAATAAAATAATTCTAAAGGAA AAAAATAAAAAATGACTTGAACTTGAAGAAGTCGTTGTTGGCCACTATGAAGACAGAACTACAGAAAGCCCAGCAGATCCACTCTCAGAC TTCACAGCAGTATCCACTTTATGATCTGGACTTGGGCAAGTTCGGTGAAAAAGTCACACAGCTGACAGACCGCTGGCAAAGGATAGATAA ACAGATCGACTTTAGGTTATGGGACCTGGAGAAACAAATCAAGCAATTGAGGAATTATCGTGATAACTATCAGGCTTTCTGCAAGTGGCT CTATGATGCTAAACGCCGCCAGGATTCCTTAGAATCCATGAAATTTGGAGATTCCAACACAGTCATGCGGTTTTTGAATGAGCAGAAGAA CTTGCACAGTGAAATATCTGGCAAACGAGACAAATCAGAGGAAGTACAAAAAATTGCTGAACTTTGCGCCAATTCAATTAAGGATTATGA GCTCCAGCTGGCCTCATACACCTCAGGACTGGAAACTCTGCTGAACATACCTATCAAGAGGACCATGATTCAGTCCCCTTCTGGGGTGAT TCTGCAAGAGGCTGCAGATGTTCATGCTCGGTACATTGAACTACTTACAAGATCTGGAGACTATTACAGGTTCTTAAGTGAGATGCTGAA GAGTTTGGAAGATCTGAAGCTGAAAAATACCAAGATCGAAGTTTTGGAAGAGGAGCTCAGACTGGCCCGAGATGCCAACTCGGAAAACTG TAATAAGAACAAATTCCTGGATCAGAACCTGCAGAAATACCAGGCAGAGTGTTCCCAGTTCAAAGCGAAGCTTGCGAGCCTGGAGGAGCT GAAGAGACAGGCTGAGCTGGATGGGAAGTCGGCTAAGCAAAATCTAGACAAGTGCTACGGCCAAATAAAAGAACTCAATGAGAAGATCAC CCGACTGACTTATGAGATTGAAGATGAAAAGAGAAGAAGAAAATCTGTGGAAGACAGATTTGACCAACAGAAGAATGACTATGACCAACT GCAGAAAGCAAGGCAATGTGAAAAGGAGAACCTTGGTTGGCAGAAATTAGAGTCTGAGAAAGCCATCAAGGAGAAGGAGTACGAGATTGA AAGGTTGAGGGTTCTACTGCAGGAAGAAGGCACCCGGAAGAGAGAATATGAAAATGAGCTGGCAAAGGCATCTAATAGGATTCAGGAATC AAAGAATCAGTGTACTCAGGTGGTACAGGAAAGAGAGAGCCTTCTGGTGAAAATCAAAGTCCTGGAGCAAGACAAGGCAAGGCTGCAGAG GCTGGAGGATGAGCTGAATCGTGCAAAATCAACTCTAGAGGCAGAAACCAGGGTGAAACAGCGCCTGGAGTGTGAGAAACAGCAAATTCA GAATGACCTGAATCAGTGGAAGACTCAATATTCCCGCAAGGAGGAGGCTATTAGGAAGATAGAATCGGAAAGAGAAAAGAGTGAGAGAGA GAAGAACAGTCTTAGGAGTGAGATCGAAAGACTCCAAGCAGAGATCAAGAGAATTGAAGAGAGGTGCAGGCGTAAGCTGGAGGATTCTAC CAGGGAGACACAGTCACAGTTAGAAACAGAACGCTCCCGATATCAGAGGGAGATTGATAAACTCAGACAGCGCCCATATGGGTCCCATCG AGAGACCCAGACTGAGTGTGAGTGGACCGTTGACACCTCCAAGCTGGTGTTTGATGGGCTGAGGAAGAAGGTGACAGCAATGCAGCTCTA TGAGTGTCAGCTGATCGACAAAACAACCTTGGACAAACTATTGAAGGGGAAGAAGTCAGTGGAAGAAGTTGCTTCTGAAATCCAGCCATT CCTTCGGGGTGCAGGATCTATCGCTGGAGCATCTGCTTCTCCTAAGGAAAAATACTCTTTGGTAGAGGCCAAGAGAAAGAAATTAATCAG CCCAGAATCCACAGTCATGCTTCTGGAGGCCCAGGCAGCTACAGGTGGTATAATTGATCCCCATCGGAATGAGAAGCTGACTGTCGACAG TGCCATAGCTCGGGACCTCATTGACTTCGATGACCGTCAGCAGATATATGCAGCAGAAAAAGCTATCACTGGTTTTGATGATCCATTTTC AGGCAAGACAGTATCTGTTTCAGAAGCCATCAAGAAAAATTTGATTGATAGAGAAACCGGAATGCGCCTGCTGGAAGCCCAGATTGCTTC AGGGGGTGTAGTAGACCCTGTGAACAGTGTCTTTTTGCCAAAAGATGTCGCCTTGGCCCGGGGGCTGATTGATAGAGATTTGTATCGATC CCTGAATGATCCCCGAGATAGTCAGAAAAACTTTGTGGATCCAGTCACCAAAAAGAAGGTCAGTTACGTGCAGCTGAAGGAACGGTGCAG AATCGAACCACATACTGGTCTGCTCTTGCTTTCAGTACAGAAGAGAAGCATGTCCTTCCAAGGAATCAGACAACCTGTGACCGTCACTGA GCTAGTAGATTCTGGTATATTGAGACCGTCCACTGTCAATGAACTGGAATCTGGTCAGATTTCTTATGACGAGGTTGGTGAGAGAATTAA GGACTTCCTCCAGGGTTCAAGCTGCATAGCAGGCATATACAATGAGACCACAAAACAGAAGCTTGGCATTTATGAGGCCATGAAAATTGG CTTAGTCCGACCTGGTACTGCTCTGGAGTTGCTGGAAGCCCAAGCAGCTACTGGCTTTATAGTGGATCCTGTTAGCAACTTGAGGTTACC AGTGGAGGAAGCCTACAAGAGAGGTCTGGTGGGCATTGAGTTCAAAGAGAAGCTCCTGTCTGCAGAACGAGCTGTCACTGGGTATAATGA TCCTGAAACAGGAAACATCATCTCTTTGTTCCAAGCCATGAATAAGGAACTCATCGAAAAGGGCCACGGTATTCGCTTATTAGAAGCACA GATCGCAACCGGGGGGATCATTGACCCAAAGGAGAGCCATCGTTTACCAGTTGACATAGCATATAAGAGGGGCTATTTCAATGAGGAACT CAGTGAGATTCTCTCAGATCCAAGTGATGATACCAAAGGATTTTTTGACCCCAACACTGAAGAAAATCTTACCTATCTGCAACTAAAAGA AAGATGCATTAAGGATGAGGAAACAGGGCTCTGTCTTCTGCCTCTGAAAGAAAAGAAGAAACAGGTGCAGACATCACAAAAGAATACCCT CAGGAAGCGTAGAGTGGTCATAGTTGACCCAGAAACCAATAAAGAAATGTCTGTTCAGGAGGCCTACAAGAAGGGCCTAATTGATTATGA AACCTTCAAAGAACTGTGTGAGCAGGAATGTGAATGGGAAGAAATAACCATCACGGGATCAGATGGCTCCACCAGGGTGGTCCTGGTAGA TAGAAAGACAGGCAGTCAGTATGATATTCAAGATGCTATTGACAAGGGCCTTGTTGACAGGAAGTTCTTTGATCAGTACCGATCCGGCAG CCTCAGCCTCACTCAATTTGCTGACATGATCTCCTTGAAAAATGGTGTCGGCACCAGCAGCAGCATGGGCAGTGGTGTCAGCGATGATGT TTTTAGCAGCTCCCGACATGAATCAGTAAGTAAGATTTCCACCATATCCAGCGTCAGGAATTTAACCATAAGGAGCAGCTCTTTTTCAGA CACCCTGGAAGAATCGAGCCCCATTGCAGCCATCTTTGACACAGAAAACCTGGAGAAAATCTCCATTACAGAAGGTATAGAGCGGGGCAT CGTTGACAGCATCACGGGTCAGAGGCTTCTGGAGGCTCAGGCCTGCACAGGTGGCATCATCCACCCAACCACGGGCCAGAAGCTGTCACT TCAGGACGCAGTCTCCCAGGGTGTGATTGACCAAGACATGGCCACCAGGCTGAAGCCTGCTCAGAAAGCCTTCATAGGCTTCGAGGGTGT GAAGGGAAAGAAGAAGATGTCAGCAGCAGAGGCAGTGAAAGAAAAATGGCTCCCGTATGAGGCTGGCCAGCGCTTCCTGGAGTTCCAGTA CCTCACGGGAGGTCTTGTTGACCCGGAAGTGCATGGGAGGATAAGCACCGAAGAAGCCATCCGGAAGGGGTTCATAGATGGCCGCGCCGC ACAGAGGCTGCAAGACACCAGCAGCTATGCCAAAATCCTGACCTGCCCCAAAACCAAATTAAAAATATCCTATAAGGATGCCATAAATCG CTCCATGGTAGAAGATATCACTGGGCTGCGCCTTCTGGAAGCCGCCTCCGTGTCGTCCAAGGGCTTACCCAGCCCTTACAACATGTCTTC GGCTCCGGGGTCCCGCTCCGGCTCCCGCTCGGGATCTCGCTCCGGATCTCGCTCCGGGTCCCGCAGTGGGTCCCGGAGAGGAAGCTTTGA CGCCACAGGGAATTCTTCCTACTCTTATTCCTACTCATTTAGCAGTAGTTCTATTGGGCACTAGTAGTCAGTTGGGAGTGGTTGCTATAC CTTGACTTCATTTATATGAATTTCCACTTTATTAAATAATAGAAAAGAAAATCCCGGTGCTTGCAGTAGAGTGATAGGACATTCTATGCT TACAGAAAATATAGCCATGATTGAAATCAAATAGTAAAGGCTGTTCTGGCTTTTTATCTTCTTAGCTCATCTTAAATAAGCAGTACACTT GGATGCAGTGCGTCTGAAGTGCTAATCAGTTGTAACAATAGCACAAATCGAACTTAGGATTTGTTTCTTCTCTTCTGTGTTTCGATTTTT GATCAATTCTTTAATTTTGGAAGCCTATAATACAGTTTTCTATTCTTGGAGATAAAAATTAAATGGATCACTGATATTTTAGTCATTCTG CTTCTCATCTAAATATTTCCATATTCTGTATTAGGAGAAAATTACCCTCCCAGCACCAGCCCCCCTCTCAAACCCCCAACCCAAAACCAA GCATTTTGGAATGAGTCTCCTTTAGTTTCAGAGTGTGGATTGTATAACCCATATACTCTTCGATGTACTTGTTTGGTTTGGTATTAATTT GACTGTGCATGACAGCGGCAATCTTTTCTTTGGTCAAAGTTTTCTGTTTATTTTGCTTGTCATATTCGATGTACTTTAAGGTGTCTTTAT >37069_37069_2_HNRNPA2B1-DSP_HNRNPA2B1_chr7_26231467_ENST00000356674_DSP_chr6_7575528_ENST00000418664_length(amino acids)=1455AA_BP= MNLKKSLLATMKTELQKAQQIHSQTSQQYPLYDLDLGKFGEKVTQLTDRWQRIDKQIDFRLWDLEKQIKQLRNYRDNYQAFCKWLYDAKR RQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAELCANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAA DVHARYIELLTRSGDYYRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLEELKRQAE LDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVL LQEEGTRKREYENELAKASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQ WKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTE CEWTVDTSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGSIAGASASPKEKYSLVEAKRKKLISPESTV MLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVD PVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRSMSFQGIRQPVTVTELVDSG ILRPSTVNELESGQISYDEVGERIKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAY KRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILS DPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKEL CEQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQFADMISLKNGVGTSSSMGSGVSDDVFSSSR HESVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVS QGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQD TSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNS -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for HNRNPA2B1-DSP |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000379802 | 16 | 24 | 1_584 | 812.0 | 2872.0 | plakophilin 1 and junction plakoglobin | |
| Tgene | DSP | chr7:26231467 | chr6:7575528 | ENST00000418664 | 16 | 24 | 1_584 | 812.0 | 2273.0 | plakophilin 1 and junction plakoglobin |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for HNRNPA2B1-DSP |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for HNRNPA2B1-DSP |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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