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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:HNRNPC-HNRNPC (FusionGDB2 ID:37130)

Fusion Gene Summary for HNRNPC-HNRNPC

Fusion gene summary

Fusion gene information	Fusion gene name: HNRNPC-HNRNPC
	Fusion gene ID: 37130
		Hgene	Tgene
	Gene symbol	HNRNPC	HNRNPC
	Gene ID	3183	3183
	Gene name	heterogeneous nuclear ribonucleoprotein C	heterogeneous nuclear ribonucleoprotein C
	Synonyms	C1\|C2\|HNRNP\|HNRPC\|SNRPC	C1\|C2\|HNRNP\|HNRPC\|SNRPC
	Cytomap	14q11.2	14q11.2
	Type of gene	protein-coding	protein-coding
	Description	heterogeneous nuclear ribonucleoproteins C1/C2heterogeneous nuclear ribonucleoprotein C (C1/C2)hnRNP C1/C2nuclear ribonucleoprotein particle C1 proteinnuclear ribonucleoprotein particle C2 protein	heterogeneous nuclear ribonucleoproteins C1/C2heterogeneous nuclear ribonucleoprotein C (C1/C2)hnRNP C1/C2nuclear ribonucleoprotein particle C1 proteinnuclear ribonucleoprotein particle C2 protein
	Modification date	20200322	20200322
	UniProtAcc	P07910	P07910
	Ensembl transtripts involved in fusion gene	ENST00000320084, ENST00000336053, ENST00000420743, ENST00000430246, ENST00000449098, ENST00000553300, ENST00000553753, ENST00000554455, ENST00000554969, ENST00000555309, ENST00000555883, ENST00000555914, ENST00000556142, ENST00000556513, ENST00000556628, ENST00000556897, ENST00000557201,	ENST00000320084, ENST00000336053, ENST00000420743, ENST00000430246, ENST00000449098, ENST00000553300, ENST00000553753, ENST00000554455, ENST00000554969, ENST00000555309, ENST00000555883, ENST00000555914, ENST00000556142, ENST00000556513, ENST00000556628, ENST00000556897, ENST00000557201,
Fusion gene scores	* DoF score	20 X 19 X 10=3800	17 X 11 X 5=935
	# samples	26	20
	** MAII score	log2(26/3800*10)=-3.86941589018986 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(20/935*10)=-2.22496636500027 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: HNRNPC [Title/Abstract] AND HNRNPC [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	HNRNPC(21707036)-HNRNPC(21706233), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across HNRNPC (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across HNRNPC (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS5.0	N/A	AA807200	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+

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Fusion Gene ORF analysis for HNRNPC-HNRNPC

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
intron-intron	ENST00000320084	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000320084	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000336053	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000420743	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000430246	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000449098	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553300	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000553753	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554455	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000554969	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555309	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555883	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000555914	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556142	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556513	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556628	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000556897	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000320084	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000336053	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000420743	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000430246	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000449098	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000553300	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000553753	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000554455	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000554969	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000555309	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000555883	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000555914	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000556142	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000556513	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000556628	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000556897	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+
intron-intron	ENST00000557201	ENST00000557201	HNRNPC	chr14	21707036	+	HNRNPC	chr14	21706233	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

No-coding score

Coding score

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Fusion Genomic Features for HNRNPC-HNRNPC

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for HNRNPC-HNRNPC

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:21707036/:21706233)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
HNRNPC P07910	HNRNPC P07910
FUNCTION: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621). Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides (PubMed:8264621). May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671). {ECO:0000269\|PubMed:12509468, ECO:0000269\|PubMed:16010978, ECO:0000269\|PubMed:25719671, ECO:0000269\|PubMed:7567451, ECO:0000269\|PubMed:8264621}.	FUNCTION: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621). Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides (PubMed:8264621). May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671). {ECO:0000269\|PubMed:12509468, ECO:0000269\|PubMed:16010978, ECO:0000269\|PubMed:25719671, ECO:0000269\|PubMed:7567451, ECO:0000269\|PubMed:8264621}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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Fusion Gene Sequence for HNRNPC-HNRNPC

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for HNRNPC-HNRNPC

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for HNRNPC-HNRNPC

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for HNRNPC-HNRNPC

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source