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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:HNRNPH3-RAB18 (FusionGDB2 ID:37216) |
Fusion Gene Summary for HNRNPH3-RAB18 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: HNRNPH3-RAB18 | Fusion gene ID: 37216 | Hgene | Tgene | Gene symbol | HNRNPH3 | RAB18 | Gene ID | 3189 | 22931 |
| Gene name | heterogeneous nuclear ribonucleoprotein H3 | RAB18, member RAS oncogene family | |
| Synonyms | 2H9|HNRPH3 | RAB18LI1|WARBM3 | |
| Cytomap | 10q21.3 | 10p12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | heterogeneous nuclear ribonucleoprotein H3heterogeneous nuclear ribonucleoprotein 2H9hnRNP 2H9hnRNP H3 | ras-related protein Rab-18RAB18 small GTPase | |
| Modification date | 20200313 | 20200327 | |
| UniProtAcc | P31942 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000469172, ENST00000265866, ENST00000354695, ENST00000441000, | ENST00000356940, ENST00000535776, ENST00000465772, ENST00000375802, | |
| Fusion gene scores | * DoF score | 9 X 7 X 6=378 | 8 X 7 X 4=224 |
| # samples | 10 | 9 | |
| ** MAII score | log2(10/378*10)=-1.91838623444635 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/224*10)=-1.31550182572793 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: HNRNPH3 [Title/Abstract] AND RAB18 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | HNRNPH3(70097090)-RAB18(27815757), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across HNRNPH3 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across RAB18 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | Non-Cancer | TCGA-HU-A4GP-11A | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
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Fusion Gene ORF analysis for HNRNPH3-RAB18 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000469172 | ENST00000356940 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| 3UTR-3CDS | ENST00000469172 | ENST00000535776 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| 3UTR-3UTR | ENST00000469172 | ENST00000465772 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| 3UTR-intron | ENST00000469172 | ENST00000375802 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| 5CDS-3UTR | ENST00000265866 | ENST00000465772 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| 5CDS-3UTR | ENST00000354695 | ENST00000465772 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| 5CDS-3UTR | ENST00000441000 | ENST00000465772 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| 5CDS-intron | ENST00000265866 | ENST00000375802 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| 5CDS-intron | ENST00000354695 | ENST00000375802 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| 5CDS-intron | ENST00000441000 | ENST00000375802 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| In-frame | ENST00000265866 | ENST00000356940 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| In-frame | ENST00000265866 | ENST00000535776 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| In-frame | ENST00000354695 | ENST00000356940 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| In-frame | ENST00000354695 | ENST00000535776 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| In-frame | ENST00000441000 | ENST00000356940 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| In-frame | ENST00000441000 | ENST00000535776 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000265866 | HNRNPH3 | chr10 | 70097090 | + | ENST00000356940 | RAB18 | chr10 | 27815757 | + | 4937 | 277 | 165 | 773 | 202 |
| ENST00000265866 | HNRNPH3 | chr10 | 70097090 | + | ENST00000535776 | RAB18 | chr10 | 27815757 | + | 1805 | 277 | 165 | 581 | 138 |
| ENST00000441000 | HNRNPH3 | chr10 | 70097090 | + | ENST00000356940 | RAB18 | chr10 | 27815757 | + | 4916 | 256 | 144 | 752 | 202 |
| ENST00000441000 | HNRNPH3 | chr10 | 70097090 | + | ENST00000535776 | RAB18 | chr10 | 27815757 | + | 1784 | 256 | 144 | 560 | 138 |
| ENST00000354695 | HNRNPH3 | chr10 | 70097090 | + | ENST00000356940 | RAB18 | chr10 | 27815757 | + | 4890 | 230 | 118 | 726 | 202 |
| ENST00000354695 | HNRNPH3 | chr10 | 70097090 | + | ENST00000535776 | RAB18 | chr10 | 27815757 | + | 1758 | 230 | 118 | 534 | 138 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000265866 | ENST00000356940 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + | 0.002192915 | 0.9978071 |
| ENST00000265866 | ENST00000535776 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + | 0.003783235 | 0.9962167 |
| ENST00000441000 | ENST00000356940 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + | 0.002158838 | 0.9978411 |
| ENST00000441000 | ENST00000535776 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + | 0.00430859 | 0.9956915 |
| ENST00000354695 | ENST00000356940 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + | 0.002050693 | 0.9979493 |
| ENST00000354695 | ENST00000535776 | HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815757 | + | 0.005176264 | 0.9948237 |
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Fusion Genomic Features for HNRNPH3-RAB18 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815756 | + | 3.41E-05 | 0.9999659 |
| HNRNPH3 | chr10 | 70097090 | + | RAB18 | chr10 | 27815756 | + | 3.41E-05 | 0.9999659 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for HNRNPH3-RAB18 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:70097090/chr10:27815757) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| HNRNPH3 | . |
| FUNCTION: Involved in the splicing process and participates in early heat shock-induced splicing arrest. Due to their great structural variations the different isoforms may possess different functions in the splicing reaction. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | RAB18 | chr10:70097090 | chr10:27815757 | ENST00000356940 | 1 | 7 | 122_125 | 41 | 207.0 | Nucleotide binding | Note=GTP | |
| Tgene | RAB18 | chr10:70097090 | chr10:27815757 | ENST00000356940 | 1 | 7 | 151_153 | 41 | 207.0 | Nucleotide binding | Note=GTP | |
| Tgene | RAB18 | chr10:70097090 | chr10:27815757 | ENST00000356940 | 1 | 7 | 63_67 | 41 | 207.0 | Nucleotide binding | Note=GTP | |
| Tgene | RAB18 | chr10:70097090 | chr10:27815757 | ENST00000535776 | 1 | 5 | 122_125 | 41 | 143.0 | Nucleotide binding | Note=GTP | |
| Tgene | RAB18 | chr10:70097090 | chr10:27815757 | ENST00000535776 | 1 | 5 | 151_153 | 41 | 143.0 | Nucleotide binding | Note=GTP | |
| Tgene | RAB18 | chr10:70097090 | chr10:27815757 | ENST00000535776 | 1 | 5 | 63_67 | 41 | 143.0 | Nucleotide binding | Note=GTP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | HNRNPH3 | chr10:70097090 | chr10:27815757 | ENST00000265866 | + | 2 | 10 | 108_344 | 37 | 347.0 | Compositional bias | Note=Gly-rich |
| Hgene | HNRNPH3 | chr10:70097090 | chr10:27815757 | ENST00000354695 | + | 2 | 10 | 108_344 | 37 | 332.0 | Compositional bias | Note=Gly-rich |
| Hgene | HNRNPH3 | chr10:70097090 | chr10:27815757 | ENST00000265866 | + | 2 | 10 | 16_93 | 37 | 347.0 | Domain | RRM 1 |
| Hgene | HNRNPH3 | chr10:70097090 | chr10:27815757 | ENST00000265866 | + | 2 | 10 | 195_270 | 37 | 347.0 | Domain | RRM 2 |
| Hgene | HNRNPH3 | chr10:70097090 | chr10:27815757 | ENST00000354695 | + | 2 | 10 | 16_93 | 37 | 332.0 | Domain | RRM 1 |
| Hgene | HNRNPH3 | chr10:70097090 | chr10:27815757 | ENST00000354695 | + | 2 | 10 | 195_270 | 37 | 332.0 | Domain | RRM 2 |
| Tgene | RAB18 | chr10:70097090 | chr10:27815757 | ENST00000356940 | 1 | 7 | 37_45 | 41 | 207.0 | Motif | Effector region | |
| Tgene | RAB18 | chr10:70097090 | chr10:27815757 | ENST00000535776 | 1 | 5 | 37_45 | 41 | 143.0 | Motif | Effector region | |
| Tgene | RAB18 | chr10:70097090 | chr10:27815757 | ENST00000356940 | 1 | 7 | 15_23 | 41 | 207.0 | Nucleotide binding | Note=GTP | |
| Tgene | RAB18 | chr10:70097090 | chr10:27815757 | ENST00000535776 | 1 | 5 | 15_23 | 41 | 143.0 | Nucleotide binding | Note=GTP |
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Fusion Gene Sequence for HNRNPH3-RAB18 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >37216_37216_1_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000265866_RAB18_chr10_27815757_ENST00000356940_length(transcript)=4937nt_BP=277nt TGCGCAGCTCCCTAAGCGGTTGTCACCGCTGGAGACGGTTGGGAGAACCGTTGTGGCGAGCGCTACACGAGGCAAACGACTTCTCCCTTC TTTGAACTGGACCCCGCGAGCACCAGAGTCGGCGTAACTATCGCCTGACAGGCATTTAAATCAAACGGTATTGAGATGGATTGGGTTATG AAACATAATGGTCCAAATGACGCTAGTGATGGGACAGTACGACTTCGTGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTC TTTCAAGGTGTTGACTTTAAGGTGAAAACAATTTCAGTGGATGGAAATAAGGCTAAACTTGCAATATGGGATACTGCTGGTCAAGAGAGG TTTAGAACATTAACTCCCAGCTATTATAGAGGTGCACAGGGTGTTATATTAGTTTATGATGTCACAAGAAGAGATACATTTGTTAAACTG GATAATTGGTTAAATGAATTGGAAACATACTGTACAAGAAATGACATAGTAAACATGCTAGTTGGAAATAAAATCGATAAGGAAAATCGT GAAGTCGATAGAAATGAAGGCCTGAAATTTGCACGAAAGCATTCCATGTTATTTATAGAGGCAAGTGCAAAAACCTGTGATGGTGTACAA TGTGCCTTTGAAGAACTTGTTGAAAAGATCATTCAGACCCCTGGACTGTGGGAAAGTGAGAACCAGAATAAAGGAGTCAAACTGTCACAC AGGGAAGAAGGCCAAGGAGGAGGAGCCTGTGGTGGTTATTGCTCTGTGTTATAAACTCTGGGAAATTCCATCTCTTGCATATTTGATCAG ATAGTGACATCTTTCTGTATATAAACTCTTTAACTGCTATTTTAGGGACCTTGCAGTTTGCACATAATTGTTTTATATCATAGCAGTAAA TATTTGCAAGAAATCCCACTCATCGACCCCGGGTAAAATGTTATGGTAAGCATGCACAGTTTGCAGTCTACAGTTTTTTTATGTAGCACA AAATAGGTGTACCTTTATAAGTACATTCAATTTTATGATTTACATTTATCATGTAATTTTTAAAAAAATCCATCTATCTAGGATATGTTG ATACAAAGTCTGCTTTTGCTATTCTTTTTGCTTAAATACTCCTATCATTTTCTGAATTACTTGGTATTTAGAACTCCTAGCACCACGGGG AAGAATAGAGGTATCATCAAACGTGGCAAATTTTCTTTCAGGAATAATAAAGAGCATGATTCCACAGCTTTTCTGGGATGTTTGAGATTC TTTTTTAGTACTAAGCAAAATTCTCATCACAGAATGTAGCCCAGGCCAATTTATAACTAAATCTCTATTTGTTCAGATGATGCTTCTAAA ACAGCATTGATAGGTTAAAGAAGCTTGGTATTTTTAATTTACTTCAATGATTAGCTCAGTTGCTTAACTGGAGTTTTAATCCTGTGATAT GTACATTGGATTCATGACTGTGCAGCATTTTTAGTTATGTGGTGTTTGGCAGAATGACAATAAGGTTTTCCCCCATTTTGGTTTCAGGAG GACATGAATAGTGTGTTTATTGTAACTCCTCATACACTTTTAAAACCAACATCTTTTTTCATAAATGTTGGTAGTGTTTGTCCAGGTACC TTAACTGTAGCTTGTGTAATGTTGATGAATATCTGTATCTTACGGCTTCCATAATGGCTAGTTGATATTCAAAAACCTATTTCTGTGTTT TGAGGGGTGGGGAAAAAAAACACTAAGTGATAATTTGAAAAAGGCATATTGCTTCCAGATTCTGATGTGTGAGGGAAAATACTGTCACAA TGAAAATCTTGACAATTTACTTAACAAGTAACCAGTAGTTCATCAAAACCAACTTGTACAGACTAATAAATCTTTTTCACAGTATTCAGT TTTCTCACCTCTTGCTATTGTATATTGTAGATTTTTTTCATTCATGTGTTATTTAATTTACACTGATCTCTGCTATTTTAACCCCCCAAA TAAGTTATTTGTCCTTTAAGGTTGGTTACTATAATACCCCTCAGTAAGATTCCAGTATTAATTTCTGGGCAGTTTGTTCTCTGTATACAA TTGCAAATGATAAGCATTTTTGTGAGTGACCACCTTTGCAATATGTTTGTTAATTTACTTCATGTTGGGTTCTTTCTGAAATGTACATCT TTACATATAAAAACCTCACATTCTACTTGATTTACACTTCCTAGTCTACATTACATGTGGTTGAAGGTTTTATACATTCTATATGCTTTT ACTAAATATACAAGATTTACTACTAGAAATTTGGAGAAAGAACACTAACACATGTACTTGTGATTTGTTCATGTTATATTAAAACTTGAG ATTTGTGTATTTATGTAGAGTCTGTATTGACAAGACTGTTGTTTTTTGCTCCTTGAGCTATATAATAATCTGTGTATTGGATTGTTGTCT TGATTTGGTCTAAATTTGAATATATATGAGTTACTTGAATATAACAAAAATGAATTTTGTTTGATAGATTTATATTGTAACCTTTTTCTA GTTCTTGAATAAATATAGCCTGCTTTCCCTAGATGCATTTGTGTAGGAAGTATATACATTTCCCTATTACTCTCATCAGCTGAAGAATAT GTACTATTGTGTTACTCAAATTATGTGGCTTTCATTTTGTTGTTTTGTTGCAAGCTTAGTGTTTTGTAGTGGAGGTTTTGTAAATGAAAC AGTTGTAATATCTAAGGTCAGGCACCTAGTAACAGGGTTTTGTTAATTCTTTTCAGAATCATTGAAGCAGTCTTAAAGGGTCTTTTGCAG ATGGTACAAATTAGAACAATTAGAATATAGTATTTTGAGTTCTAGTAGTACTGAGATTGACCCAAACAAATAAAAAACTATTCAATTTCT GAGTAATAGTTAATATTTATTGAAAGCTTCCTTGGTGCCAGATGCCTTTCTAAGTGCTGAATTATCTCATTAAACCTCACAGCAACCTTA AGAGATTAGTACTCCTATTATGCCCATTTTAAAGGTGAGGACAACACAATGTAGGTATGTTAGGTAACCCCCAAAGATCACATAGCTACT CAGTCACTGAGCTGGATTCCAGTCATGGCATTTTTACTTCTGAGCCCATACTCTTCACCATCGCTCATTTTACAATGGGTAGTTAGTTAC CAGCTTTTTGTAACACAACCAAGTTAAGGCAGTTCCACTATTTCTTTATCACTCTTTTGTTATATGTAATAGAAGTATTTCACACTTTTG GGTTATAGAGTAAATCCCATGATGTAAACCTACCTCATAAGTCATGTGACATAAAAGTTAAGGTAGTGGAGTAGGTGGTCTTATTTCTTT CACCTGCTCAGAGTGGACTGAAAATCCTGACTTAGAAAAGGTACAAAGTTAGGGGACTTATGGTACCTTCACTTTTTATGTGAGAATAGA AATTATGGAAACAGTAATTTGCTCAAAACTGAAATCTGGGGTGATGTTTTCATTTCATGTATTTGATTGCCATCCATAAACTCATACTTG GTGTTGACATTCTAGCTGAGTGTTGTGGAAATAGACTTGATTTTGATTCATCGTAGCTTGCATGGTCAAGAGACATGATTCTCTACTAAG GGTGGGGCTAGCACCATAGCTCATAAAAGAATCCTTCTTACACCAGTACTTGTTCTGCCTGTGAGTTGGCACAGACTTACCTAATAACCA TAGTGTCTTTAAGTACAACTTAATACATATTTTTTCTGTGTATTTTTTTCAAATGAACTCAACAATTCTTCAGGTATTATAGATCAGAGA TCCTCTCCATATTCAAGCATTATGCTTCTCTTTCTTGGGGGTACATTTCACTAGTAATACTTAGGAAGTTATTTTGTCTTTCCTGTATTT CCCTAGTTAAGTATAGGGGTAAAAACGTTATTCAGCTTTCAGAAGACATTGTTCTGACTCCGACCCTGCCGTGTATACTCAACTATATAG ACTTCACCCTGGGTTTTGCCTAAACTGTTGAAAGACGAGAATAAATAGACATAGACAGGCTAGCTAAGTCAAGACTAGGGGCTAAGGAAT ATAGAATCACCCAGGTCTTTTTTTTTTTTTTTAATTTTTCTCTCCTCAGTTGGGAACATCTATCATGCTGGAGGACTACTGTGATGGGGC TTTACATTTTACTGTTTTGTTGCTAGCTTATTGTTTCATACTTGGGAATCAGTCATGTTTCTGATTGTGGTATAAAGTTTGCTTAAGTGC CCCTTAGTTAAAGCTGTTCAATGAATGTAAGCACACACACACCTACACACATATTTTGAATAGTCGTGTGTTCATGCCTGTTCTCAGTCT TGTCCCCTTTACCGTTTCTCATGCAGGTTATTTCTTGCTTTTTTTTTTTTTCCTCTTTTTTAACCGGAGAAGCAACAAATTACGTAGTTT TTTTTGTGTTTCTTTGATTACTAGTGAGCTTGAGTACTTTTAATATTTTATTGGATATGTTTGTGACTGACTTTAATTTCTTGTTTGTGT GTGCTGTGGCTGCCCGATCCAGCACCTACTTCCTTCTCCCACCATACCACCCCCACCCCCACCCCTGCAAACAATTGGCATGTGGTTTGG GTGGCATTGTCACACCCTCGGCTTTCTAGATTAACCCAGTTACCTTTTAGCAGTGCCCCACTTCCCCAGTAGCAATGGTTCAGGGGTAGG CACCTGACCCAGACCAGACTACTGAGATAAAGATGTTTGCCTAGGCTTTTTCAGGAGCAATTGAAGACATCTTGTTGGAGATAGTGTGCT GGGAGGAGTCACATTCTGAACTTGCTGCAGCTCGTTTTTCTAATATAAAGGAACCAGCCTGAGGCAGTACCAGGGTGAGAGGGAGTCTAT >37216_37216_1_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000265866_RAB18_chr10_27815757_ENST00000356940_length(amino acids)=202AA_BP=37 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRD TFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKG -------------------------------------------------------------- >37216_37216_2_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000265866_RAB18_chr10_27815757_ENST00000535776_length(transcript)=1805nt_BP=277nt TGCGCAGCTCCCTAAGCGGTTGTCACCGCTGGAGACGGTTGGGAGAACCGTTGTGGCGAGCGCTACACGAGGCAAACGACTTCTCCCTTC TTTGAACTGGACCCCGCGAGCACCAGAGTCGGCGTAACTATCGCCTGACAGGCATTTAAATCAAACGGTATTGAGATGGATTGGGTTATG AAACATAATGGTCCAAATGACGCTAGTGATGGGACAGTACGACTTCGTGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTC TTTCAAGGTGTTGACTTTAAGGTGAAAACAATTTCAGTGGATGGAAATAAGGCTAAACTTGCAATATGGGAAAATCGTGAAGTCGATAGA AATGAAGGCCTGAAATTTGCACGAAAGCATTCCATGTTATTTATAGAGGCAAGTGCAAAAACCTGTGATGGTGTACAATGTGCCTTTGAA GAACTTGTTGAAAAGATCATTCAGACCCCTGGACTGTGGGAAAGTGAGAACCAGAATAAAGGAGTCAAACTGTCACACAGGGAAGAAGGC CAAGGAGGAGGAGCCTGTGGTGGTTATTGCTCTGTGTTATAAACTCTGGGAAATTCCATCTCTTGCATATTTGATCAGATAGTGACATCT TTCTGTATATAAACTCTTTAACTGCTATTTTAGGGACCTTGCAGTTTGCACATAATTGTTTTATATCATAGCAGTAAATATTTGCAAGAA ATCCCACTCATCGACCCCGGGTAAAATGTTATGGTAAGCATGCACAGTTTGCAGTCTACAGTTTTTTTATGTAGCACAAAATAGGTGTAC CTTTATAAGTACATTCAATTTTATGATTTACATTTATCATGTAATTTTTAAAAAAATCCATCTATCTAGGATATGTTGATACAAAGTCTG CTTTTGCTATTCTTTTTGCTTAAATACTCCTATCATTTTCTGAATTACTTGGTATTTAGAACTCCTAGCACCACGGGGAAGAATAGAGGT ATCATCAAACGTGGCAAATTTTCTTTCAGGAATAATAAAGAGCATGATTCCACAGCTTTTCTGGGATGTTTGAGATTCTTTTTTAGTACT AAGCAAAATTCTCATCACAGAATGTAGCCCAGGCCAATTTATAACTAAATCTCTATTTGTTCAGATGATGCTTCTAAAACAGCATTGATA GGTTAAAGAAGCTTGGTATTTTTAATTTACTTCAATGATTAGCTCAGTTGCTTAACTGGAGTTTTAATCCTGTGATATGTACATTGGATT CATGACTGTGCAGCATTTTTAGTTATGTGGTGTTTGGCAGAATGACAATAAGGTTTTCCCCCATTTTGGTTTCAGGAGGACATGAATAGT GTGTTTATTGTAACTCCTCATACACTTTTAAAACCAACATCTTTTTTCATAAATGTTGGTAGTGTTTGTCCAGGTACCTTAACTGTAGCT TGTGTAATGTTGATGAATATCTGTATCTTACGGCTTCCATAATGGCTAGTTGATATTCAAAAACCTATTTCTGTGTTTTGAGGGGTGGGG AAAAAAAACACTAAGTGATAATTTGAAAAAGGCATATTGCTTCCAGATTCTGATGTGTGAGGGAAAATACTGTCACAATGAAAATCTTGA CAATTTACTTAACAAGTAACCAGTAGTTCATCAAAACCAACTTGTACAGACTAATAAATCTTTTTCACAGTATTCAGTTTTCTCACCTCT TGCTATTGTATATTGTAGATTTTTTTCATTCATGTGTTATTTAATTTACACTGATCTCTGCTATTTTAACCCCCCAAATAAGTTATTTGT >37216_37216_2_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000265866_RAB18_chr10_27815757_ENST00000535776_length(amino acids)=138AA_BP=37 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGVDFKVKTISVDGNKAKLAIWENREVDRNEGLKFARKHSMLFIEASAKTCDGV -------------------------------------------------------------- >37216_37216_3_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000354695_RAB18_chr10_27815757_ENST00000356940_length(transcript)=4890nt_BP=230nt CCGTTGTGGCGAGCGCTACACGAGGCAAACGACTTCTCCCTTCTTTGAACTGGACCCCGCGAGCACCAGAGTCGGCGTAACTATCGCCTG ACAGGCATTTAAATCAAACGGTATTGAGATGGATTGGGTTATGAAACATAATGGTCCAAATGACGCTAGTGATGGGACAGTACGACTTCG TGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTCTTTCAAGGTGTTGACTTTAAGGTGAAAACAATTTCAGTGGATGGAAA TAAGGCTAAACTTGCAATATGGGATACTGCTGGTCAAGAGAGGTTTAGAACATTAACTCCCAGCTATTATAGAGGTGCACAGGGTGTTAT ATTAGTTTATGATGTCACAAGAAGAGATACATTTGTTAAACTGGATAATTGGTTAAATGAATTGGAAACATACTGTACAAGAAATGACAT AGTAAACATGCTAGTTGGAAATAAAATCGATAAGGAAAATCGTGAAGTCGATAGAAATGAAGGCCTGAAATTTGCACGAAAGCATTCCAT GTTATTTATAGAGGCAAGTGCAAAAACCTGTGATGGTGTACAATGTGCCTTTGAAGAACTTGTTGAAAAGATCATTCAGACCCCTGGACT GTGGGAAAGTGAGAACCAGAATAAAGGAGTCAAACTGTCACACAGGGAAGAAGGCCAAGGAGGAGGAGCCTGTGGTGGTTATTGCTCTGT GTTATAAACTCTGGGAAATTCCATCTCTTGCATATTTGATCAGATAGTGACATCTTTCTGTATATAAACTCTTTAACTGCTATTTTAGGG ACCTTGCAGTTTGCACATAATTGTTTTATATCATAGCAGTAAATATTTGCAAGAAATCCCACTCATCGACCCCGGGTAAAATGTTATGGT AAGCATGCACAGTTTGCAGTCTACAGTTTTTTTATGTAGCACAAAATAGGTGTACCTTTATAAGTACATTCAATTTTATGATTTACATTT ATCATGTAATTTTTAAAAAAATCCATCTATCTAGGATATGTTGATACAAAGTCTGCTTTTGCTATTCTTTTTGCTTAAATACTCCTATCA TTTTCTGAATTACTTGGTATTTAGAACTCCTAGCACCACGGGGAAGAATAGAGGTATCATCAAACGTGGCAAATTTTCTTTCAGGAATAA TAAAGAGCATGATTCCACAGCTTTTCTGGGATGTTTGAGATTCTTTTTTAGTACTAAGCAAAATTCTCATCACAGAATGTAGCCCAGGCC AATTTATAACTAAATCTCTATTTGTTCAGATGATGCTTCTAAAACAGCATTGATAGGTTAAAGAAGCTTGGTATTTTTAATTTACTTCAA TGATTAGCTCAGTTGCTTAACTGGAGTTTTAATCCTGTGATATGTACATTGGATTCATGACTGTGCAGCATTTTTAGTTATGTGGTGTTT GGCAGAATGACAATAAGGTTTTCCCCCATTTTGGTTTCAGGAGGACATGAATAGTGTGTTTATTGTAACTCCTCATACACTTTTAAAACC AACATCTTTTTTCATAAATGTTGGTAGTGTTTGTCCAGGTACCTTAACTGTAGCTTGTGTAATGTTGATGAATATCTGTATCTTACGGCT TCCATAATGGCTAGTTGATATTCAAAAACCTATTTCTGTGTTTTGAGGGGTGGGGAAAAAAAACACTAAGTGATAATTTGAAAAAGGCAT ATTGCTTCCAGATTCTGATGTGTGAGGGAAAATACTGTCACAATGAAAATCTTGACAATTTACTTAACAAGTAACCAGTAGTTCATCAAA ACCAACTTGTACAGACTAATAAATCTTTTTCACAGTATTCAGTTTTCTCACCTCTTGCTATTGTATATTGTAGATTTTTTTCATTCATGT GTTATTTAATTTACACTGATCTCTGCTATTTTAACCCCCCAAATAAGTTATTTGTCCTTTAAGGTTGGTTACTATAATACCCCTCAGTAA GATTCCAGTATTAATTTCTGGGCAGTTTGTTCTCTGTATACAATTGCAAATGATAAGCATTTTTGTGAGTGACCACCTTTGCAATATGTT TGTTAATTTACTTCATGTTGGGTTCTTTCTGAAATGTACATCTTTACATATAAAAACCTCACATTCTACTTGATTTACACTTCCTAGTCT ACATTACATGTGGTTGAAGGTTTTATACATTCTATATGCTTTTACTAAATATACAAGATTTACTACTAGAAATTTGGAGAAAGAACACTA ACACATGTACTTGTGATTTGTTCATGTTATATTAAAACTTGAGATTTGTGTATTTATGTAGAGTCTGTATTGACAAGACTGTTGTTTTTT GCTCCTTGAGCTATATAATAATCTGTGTATTGGATTGTTGTCTTGATTTGGTCTAAATTTGAATATATATGAGTTACTTGAATATAACAA AAATGAATTTTGTTTGATAGATTTATATTGTAACCTTTTTCTAGTTCTTGAATAAATATAGCCTGCTTTCCCTAGATGCATTTGTGTAGG AAGTATATACATTTCCCTATTACTCTCATCAGCTGAAGAATATGTACTATTGTGTTACTCAAATTATGTGGCTTTCATTTTGTTGTTTTG TTGCAAGCTTAGTGTTTTGTAGTGGAGGTTTTGTAAATGAAACAGTTGTAATATCTAAGGTCAGGCACCTAGTAACAGGGTTTTGTTAAT TCTTTTCAGAATCATTGAAGCAGTCTTAAAGGGTCTTTTGCAGATGGTACAAATTAGAACAATTAGAATATAGTATTTTGAGTTCTAGTA GTACTGAGATTGACCCAAACAAATAAAAAACTATTCAATTTCTGAGTAATAGTTAATATTTATTGAAAGCTTCCTTGGTGCCAGATGCCT TTCTAAGTGCTGAATTATCTCATTAAACCTCACAGCAACCTTAAGAGATTAGTACTCCTATTATGCCCATTTTAAAGGTGAGGACAACAC AATGTAGGTATGTTAGGTAACCCCCAAAGATCACATAGCTACTCAGTCACTGAGCTGGATTCCAGTCATGGCATTTTTACTTCTGAGCCC ATACTCTTCACCATCGCTCATTTTACAATGGGTAGTTAGTTACCAGCTTTTTGTAACACAACCAAGTTAAGGCAGTTCCACTATTTCTTT ATCACTCTTTTGTTATATGTAATAGAAGTATTTCACACTTTTGGGTTATAGAGTAAATCCCATGATGTAAACCTACCTCATAAGTCATGT GACATAAAAGTTAAGGTAGTGGAGTAGGTGGTCTTATTTCTTTCACCTGCTCAGAGTGGACTGAAAATCCTGACTTAGAAAAGGTACAAA GTTAGGGGACTTATGGTACCTTCACTTTTTATGTGAGAATAGAAATTATGGAAACAGTAATTTGCTCAAAACTGAAATCTGGGGTGATGT TTTCATTTCATGTATTTGATTGCCATCCATAAACTCATACTTGGTGTTGACATTCTAGCTGAGTGTTGTGGAAATAGACTTGATTTTGAT TCATCGTAGCTTGCATGGTCAAGAGACATGATTCTCTACTAAGGGTGGGGCTAGCACCATAGCTCATAAAAGAATCCTTCTTACACCAGT ACTTGTTCTGCCTGTGAGTTGGCACAGACTTACCTAATAACCATAGTGTCTTTAAGTACAACTTAATACATATTTTTTCTGTGTATTTTT TTCAAATGAACTCAACAATTCTTCAGGTATTATAGATCAGAGATCCTCTCCATATTCAAGCATTATGCTTCTCTTTCTTGGGGGTACATT TCACTAGTAATACTTAGGAAGTTATTTTGTCTTTCCTGTATTTCCCTAGTTAAGTATAGGGGTAAAAACGTTATTCAGCTTTCAGAAGAC ATTGTTCTGACTCCGACCCTGCCGTGTATACTCAACTATATAGACTTCACCCTGGGTTTTGCCTAAACTGTTGAAAGACGAGAATAAATA GACATAGACAGGCTAGCTAAGTCAAGACTAGGGGCTAAGGAATATAGAATCACCCAGGTCTTTTTTTTTTTTTTTAATTTTTCTCTCCTC AGTTGGGAACATCTATCATGCTGGAGGACTACTGTGATGGGGCTTTACATTTTACTGTTTTGTTGCTAGCTTATTGTTTCATACTTGGGA ATCAGTCATGTTTCTGATTGTGGTATAAAGTTTGCTTAAGTGCCCCTTAGTTAAAGCTGTTCAATGAATGTAAGCACACACACACCTACA CACATATTTTGAATAGTCGTGTGTTCATGCCTGTTCTCAGTCTTGTCCCCTTTACCGTTTCTCATGCAGGTTATTTCTTGCTTTTTTTTT TTTTCCTCTTTTTTAACCGGAGAAGCAACAAATTACGTAGTTTTTTTTGTGTTTCTTTGATTACTAGTGAGCTTGAGTACTTTTAATATT TTATTGGATATGTTTGTGACTGACTTTAATTTCTTGTTTGTGTGTGCTGTGGCTGCCCGATCCAGCACCTACTTCCTTCTCCCACCATAC CACCCCCACCCCCACCCCTGCAAACAATTGGCATGTGGTTTGGGTGGCATTGTCACACCCTCGGCTTTCTAGATTAACCCAGTTACCTTT TAGCAGTGCCCCACTTCCCCAGTAGCAATGGTTCAGGGGTAGGCACCTGACCCAGACCAGACTACTGAGATAAAGATGTTTGCCTAGGCT TTTTCAGGAGCAATTGAAGACATCTTGTTGGAGATAGTGTGCTGGGAGGAGTCACATTCTGAACTTGCTGCAGCTCGTTTTTCTAATATA AAGGAACCAGCCTGAGGCAGTACCAGGGTGAGAGGGAGTCTATTGGAGCCCTTGGGAACTTCTGGATCAAATTGGACCTGAATTGAGATC >37216_37216_3_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000354695_RAB18_chr10_27815757_ENST00000356940_length(amino acids)=202AA_BP=37 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRD TFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKG -------------------------------------------------------------- >37216_37216_4_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000354695_RAB18_chr10_27815757_ENST00000535776_length(transcript)=1758nt_BP=230nt CCGTTGTGGCGAGCGCTACACGAGGCAAACGACTTCTCCCTTCTTTGAACTGGACCCCGCGAGCACCAGAGTCGGCGTAACTATCGCCTG ACAGGCATTTAAATCAAACGGTATTGAGATGGATTGGGTTATGAAACATAATGGTCCAAATGACGCTAGTGATGGGACAGTACGACTTCG TGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTCTTTCAAGGTGTTGACTTTAAGGTGAAAACAATTTCAGTGGATGGAAA TAAGGCTAAACTTGCAATATGGGAAAATCGTGAAGTCGATAGAAATGAAGGCCTGAAATTTGCACGAAAGCATTCCATGTTATTTATAGA GGCAAGTGCAAAAACCTGTGATGGTGTACAATGTGCCTTTGAAGAACTTGTTGAAAAGATCATTCAGACCCCTGGACTGTGGGAAAGTGA GAACCAGAATAAAGGAGTCAAACTGTCACACAGGGAAGAAGGCCAAGGAGGAGGAGCCTGTGGTGGTTATTGCTCTGTGTTATAAACTCT GGGAAATTCCATCTCTTGCATATTTGATCAGATAGTGACATCTTTCTGTATATAAACTCTTTAACTGCTATTTTAGGGACCTTGCAGTTT GCACATAATTGTTTTATATCATAGCAGTAAATATTTGCAAGAAATCCCACTCATCGACCCCGGGTAAAATGTTATGGTAAGCATGCACAG TTTGCAGTCTACAGTTTTTTTATGTAGCACAAAATAGGTGTACCTTTATAAGTACATTCAATTTTATGATTTACATTTATCATGTAATTT TTAAAAAAATCCATCTATCTAGGATATGTTGATACAAAGTCTGCTTTTGCTATTCTTTTTGCTTAAATACTCCTATCATTTTCTGAATTA CTTGGTATTTAGAACTCCTAGCACCACGGGGAAGAATAGAGGTATCATCAAACGTGGCAAATTTTCTTTCAGGAATAATAAAGAGCATGA TTCCACAGCTTTTCTGGGATGTTTGAGATTCTTTTTTAGTACTAAGCAAAATTCTCATCACAGAATGTAGCCCAGGCCAATTTATAACTA AATCTCTATTTGTTCAGATGATGCTTCTAAAACAGCATTGATAGGTTAAAGAAGCTTGGTATTTTTAATTTACTTCAATGATTAGCTCAG TTGCTTAACTGGAGTTTTAATCCTGTGATATGTACATTGGATTCATGACTGTGCAGCATTTTTAGTTATGTGGTGTTTGGCAGAATGACA ATAAGGTTTTCCCCCATTTTGGTTTCAGGAGGACATGAATAGTGTGTTTATTGTAACTCCTCATACACTTTTAAAACCAACATCTTTTTT CATAAATGTTGGTAGTGTTTGTCCAGGTACCTTAACTGTAGCTTGTGTAATGTTGATGAATATCTGTATCTTACGGCTTCCATAATGGCT AGTTGATATTCAAAAACCTATTTCTGTGTTTTGAGGGGTGGGGAAAAAAAACACTAAGTGATAATTTGAAAAAGGCATATTGCTTCCAGA TTCTGATGTGTGAGGGAAAATACTGTCACAATGAAAATCTTGACAATTTACTTAACAAGTAACCAGTAGTTCATCAAAACCAACTTGTAC AGACTAATAAATCTTTTTCACAGTATTCAGTTTTCTCACCTCTTGCTATTGTATATTGTAGATTTTTTTCATTCATGTGTTATTTAATTT >37216_37216_4_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000354695_RAB18_chr10_27815757_ENST00000535776_length(amino acids)=138AA_BP=37 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGVDFKVKTISVDGNKAKLAIWENREVDRNEGLKFARKHSMLFIEASAKTCDGV -------------------------------------------------------------- >37216_37216_5_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000441000_RAB18_chr10_27815757_ENST00000356940_length(transcript)=4916nt_BP=256nt GTCACCGCTGGAGACGGTTGGGAGAACCGTTGTGGCGAGCGCTACACGAGGCAAACGACTTCTCCCTTCTTTGAACTGGACCCCGCGAGC ACCAGAGTCGGCGTAACTATCGCCTGACAGGCATTTAAATCAAACGGTATTGAGATGGATTGGGTTATGAAACATAATGGTCCAAATGAC GCTAGTGATGGGACAGTACGACTTCGTGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTCTTTCAAGGTGTTGACTTTAAG GTGAAAACAATTTCAGTGGATGGAAATAAGGCTAAACTTGCAATATGGGATACTGCTGGTCAAGAGAGGTTTAGAACATTAACTCCCAGC TATTATAGAGGTGCACAGGGTGTTATATTAGTTTATGATGTCACAAGAAGAGATACATTTGTTAAACTGGATAATTGGTTAAATGAATTG GAAACATACTGTACAAGAAATGACATAGTAAACATGCTAGTTGGAAATAAAATCGATAAGGAAAATCGTGAAGTCGATAGAAATGAAGGC CTGAAATTTGCACGAAAGCATTCCATGTTATTTATAGAGGCAAGTGCAAAAACCTGTGATGGTGTACAATGTGCCTTTGAAGAACTTGTT GAAAAGATCATTCAGACCCCTGGACTGTGGGAAAGTGAGAACCAGAATAAAGGAGTCAAACTGTCACACAGGGAAGAAGGCCAAGGAGGA GGAGCCTGTGGTGGTTATTGCTCTGTGTTATAAACTCTGGGAAATTCCATCTCTTGCATATTTGATCAGATAGTGACATCTTTCTGTATA TAAACTCTTTAACTGCTATTTTAGGGACCTTGCAGTTTGCACATAATTGTTTTATATCATAGCAGTAAATATTTGCAAGAAATCCCACTC ATCGACCCCGGGTAAAATGTTATGGTAAGCATGCACAGTTTGCAGTCTACAGTTTTTTTATGTAGCACAAAATAGGTGTACCTTTATAAG TACATTCAATTTTATGATTTACATTTATCATGTAATTTTTAAAAAAATCCATCTATCTAGGATATGTTGATACAAAGTCTGCTTTTGCTA TTCTTTTTGCTTAAATACTCCTATCATTTTCTGAATTACTTGGTATTTAGAACTCCTAGCACCACGGGGAAGAATAGAGGTATCATCAAA CGTGGCAAATTTTCTTTCAGGAATAATAAAGAGCATGATTCCACAGCTTTTCTGGGATGTTTGAGATTCTTTTTTAGTACTAAGCAAAAT TCTCATCACAGAATGTAGCCCAGGCCAATTTATAACTAAATCTCTATTTGTTCAGATGATGCTTCTAAAACAGCATTGATAGGTTAAAGA AGCTTGGTATTTTTAATTTACTTCAATGATTAGCTCAGTTGCTTAACTGGAGTTTTAATCCTGTGATATGTACATTGGATTCATGACTGT GCAGCATTTTTAGTTATGTGGTGTTTGGCAGAATGACAATAAGGTTTTCCCCCATTTTGGTTTCAGGAGGACATGAATAGTGTGTTTATT GTAACTCCTCATACACTTTTAAAACCAACATCTTTTTTCATAAATGTTGGTAGTGTTTGTCCAGGTACCTTAACTGTAGCTTGTGTAATG TTGATGAATATCTGTATCTTACGGCTTCCATAATGGCTAGTTGATATTCAAAAACCTATTTCTGTGTTTTGAGGGGTGGGGAAAAAAAAC ACTAAGTGATAATTTGAAAAAGGCATATTGCTTCCAGATTCTGATGTGTGAGGGAAAATACTGTCACAATGAAAATCTTGACAATTTACT TAACAAGTAACCAGTAGTTCATCAAAACCAACTTGTACAGACTAATAAATCTTTTTCACAGTATTCAGTTTTCTCACCTCTTGCTATTGT ATATTGTAGATTTTTTTCATTCATGTGTTATTTAATTTACACTGATCTCTGCTATTTTAACCCCCCAAATAAGTTATTTGTCCTTTAAGG TTGGTTACTATAATACCCCTCAGTAAGATTCCAGTATTAATTTCTGGGCAGTTTGTTCTCTGTATACAATTGCAAATGATAAGCATTTTT GTGAGTGACCACCTTTGCAATATGTTTGTTAATTTACTTCATGTTGGGTTCTTTCTGAAATGTACATCTTTACATATAAAAACCTCACAT TCTACTTGATTTACACTTCCTAGTCTACATTACATGTGGTTGAAGGTTTTATACATTCTATATGCTTTTACTAAATATACAAGATTTACT ACTAGAAATTTGGAGAAAGAACACTAACACATGTACTTGTGATTTGTTCATGTTATATTAAAACTTGAGATTTGTGTATTTATGTAGAGT CTGTATTGACAAGACTGTTGTTTTTTGCTCCTTGAGCTATATAATAATCTGTGTATTGGATTGTTGTCTTGATTTGGTCTAAATTTGAAT ATATATGAGTTACTTGAATATAACAAAAATGAATTTTGTTTGATAGATTTATATTGTAACCTTTTTCTAGTTCTTGAATAAATATAGCCT GCTTTCCCTAGATGCATTTGTGTAGGAAGTATATACATTTCCCTATTACTCTCATCAGCTGAAGAATATGTACTATTGTGTTACTCAAAT TATGTGGCTTTCATTTTGTTGTTTTGTTGCAAGCTTAGTGTTTTGTAGTGGAGGTTTTGTAAATGAAACAGTTGTAATATCTAAGGTCAG GCACCTAGTAACAGGGTTTTGTTAATTCTTTTCAGAATCATTGAAGCAGTCTTAAAGGGTCTTTTGCAGATGGTACAAATTAGAACAATT AGAATATAGTATTTTGAGTTCTAGTAGTACTGAGATTGACCCAAACAAATAAAAAACTATTCAATTTCTGAGTAATAGTTAATATTTATT GAAAGCTTCCTTGGTGCCAGATGCCTTTCTAAGTGCTGAATTATCTCATTAAACCTCACAGCAACCTTAAGAGATTAGTACTCCTATTAT GCCCATTTTAAAGGTGAGGACAACACAATGTAGGTATGTTAGGTAACCCCCAAAGATCACATAGCTACTCAGTCACTGAGCTGGATTCCA GTCATGGCATTTTTACTTCTGAGCCCATACTCTTCACCATCGCTCATTTTACAATGGGTAGTTAGTTACCAGCTTTTTGTAACACAACCA AGTTAAGGCAGTTCCACTATTTCTTTATCACTCTTTTGTTATATGTAATAGAAGTATTTCACACTTTTGGGTTATAGAGTAAATCCCATG ATGTAAACCTACCTCATAAGTCATGTGACATAAAAGTTAAGGTAGTGGAGTAGGTGGTCTTATTTCTTTCACCTGCTCAGAGTGGACTGA AAATCCTGACTTAGAAAAGGTACAAAGTTAGGGGACTTATGGTACCTTCACTTTTTATGTGAGAATAGAAATTATGGAAACAGTAATTTG CTCAAAACTGAAATCTGGGGTGATGTTTTCATTTCATGTATTTGATTGCCATCCATAAACTCATACTTGGTGTTGACATTCTAGCTGAGT GTTGTGGAAATAGACTTGATTTTGATTCATCGTAGCTTGCATGGTCAAGAGACATGATTCTCTACTAAGGGTGGGGCTAGCACCATAGCT CATAAAAGAATCCTTCTTACACCAGTACTTGTTCTGCCTGTGAGTTGGCACAGACTTACCTAATAACCATAGTGTCTTTAAGTACAACTT AATACATATTTTTTCTGTGTATTTTTTTCAAATGAACTCAACAATTCTTCAGGTATTATAGATCAGAGATCCTCTCCATATTCAAGCATT ATGCTTCTCTTTCTTGGGGGTACATTTCACTAGTAATACTTAGGAAGTTATTTTGTCTTTCCTGTATTTCCCTAGTTAAGTATAGGGGTA AAAACGTTATTCAGCTTTCAGAAGACATTGTTCTGACTCCGACCCTGCCGTGTATACTCAACTATATAGACTTCACCCTGGGTTTTGCCT AAACTGTTGAAAGACGAGAATAAATAGACATAGACAGGCTAGCTAAGTCAAGACTAGGGGCTAAGGAATATAGAATCACCCAGGTCTTTT TTTTTTTTTTTAATTTTTCTCTCCTCAGTTGGGAACATCTATCATGCTGGAGGACTACTGTGATGGGGCTTTACATTTTACTGTTTTGTT GCTAGCTTATTGTTTCATACTTGGGAATCAGTCATGTTTCTGATTGTGGTATAAAGTTTGCTTAAGTGCCCCTTAGTTAAAGCTGTTCAA TGAATGTAAGCACACACACACCTACACACATATTTTGAATAGTCGTGTGTTCATGCCTGTTCTCAGTCTTGTCCCCTTTACCGTTTCTCA TGCAGGTTATTTCTTGCTTTTTTTTTTTTTCCTCTTTTTTAACCGGAGAAGCAACAAATTACGTAGTTTTTTTTGTGTTTCTTTGATTAC TAGTGAGCTTGAGTACTTTTAATATTTTATTGGATATGTTTGTGACTGACTTTAATTTCTTGTTTGTGTGTGCTGTGGCTGCCCGATCCA GCACCTACTTCCTTCTCCCACCATACCACCCCCACCCCCACCCCTGCAAACAATTGGCATGTGGTTTGGGTGGCATTGTCACACCCTCGG CTTTCTAGATTAACCCAGTTACCTTTTAGCAGTGCCCCACTTCCCCAGTAGCAATGGTTCAGGGGTAGGCACCTGACCCAGACCAGACTA CTGAGATAAAGATGTTTGCCTAGGCTTTTTCAGGAGCAATTGAAGACATCTTGTTGGAGATAGTGTGCTGGGAGGAGTCACATTCTGAAC TTGCTGCAGCTCGTTTTTCTAATATAAAGGAACCAGCCTGAGGCAGTACCAGGGTGAGAGGGAGTCTATTGGAGCCCTTGGGAACTTCTG >37216_37216_5_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000441000_RAB18_chr10_27815757_ENST00000356940_length(amino acids)=202AA_BP=37 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRD TFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKG -------------------------------------------------------------- >37216_37216_6_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000441000_RAB18_chr10_27815757_ENST00000535776_length(transcript)=1784nt_BP=256nt GTCACCGCTGGAGACGGTTGGGAGAACCGTTGTGGCGAGCGCTACACGAGGCAAACGACTTCTCCCTTCTTTGAACTGGACCCCGCGAGC ACCAGAGTCGGCGTAACTATCGCCTGACAGGCATTTAAATCAAACGGTATTGAGATGGATTGGGTTATGAAACATAATGGTCCAAATGAC GCTAGTGATGGGACAGTACGACTTCGTGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTCTTTCAAGGTGTTGACTTTAAG GTGAAAACAATTTCAGTGGATGGAAATAAGGCTAAACTTGCAATATGGGAAAATCGTGAAGTCGATAGAAATGAAGGCCTGAAATTTGCA CGAAAGCATTCCATGTTATTTATAGAGGCAAGTGCAAAAACCTGTGATGGTGTACAATGTGCCTTTGAAGAACTTGTTGAAAAGATCATT CAGACCCCTGGACTGTGGGAAAGTGAGAACCAGAATAAAGGAGTCAAACTGTCACACAGGGAAGAAGGCCAAGGAGGAGGAGCCTGTGGT GGTTATTGCTCTGTGTTATAAACTCTGGGAAATTCCATCTCTTGCATATTTGATCAGATAGTGACATCTTTCTGTATATAAACTCTTTAA CTGCTATTTTAGGGACCTTGCAGTTTGCACATAATTGTTTTATATCATAGCAGTAAATATTTGCAAGAAATCCCACTCATCGACCCCGGG TAAAATGTTATGGTAAGCATGCACAGTTTGCAGTCTACAGTTTTTTTATGTAGCACAAAATAGGTGTACCTTTATAAGTACATTCAATTT TATGATTTACATTTATCATGTAATTTTTAAAAAAATCCATCTATCTAGGATATGTTGATACAAAGTCTGCTTTTGCTATTCTTTTTGCTT AAATACTCCTATCATTTTCTGAATTACTTGGTATTTAGAACTCCTAGCACCACGGGGAAGAATAGAGGTATCATCAAACGTGGCAAATTT TCTTTCAGGAATAATAAAGAGCATGATTCCACAGCTTTTCTGGGATGTTTGAGATTCTTTTTTAGTACTAAGCAAAATTCTCATCACAGA ATGTAGCCCAGGCCAATTTATAACTAAATCTCTATTTGTTCAGATGATGCTTCTAAAACAGCATTGATAGGTTAAAGAAGCTTGGTATTT TTAATTTACTTCAATGATTAGCTCAGTTGCTTAACTGGAGTTTTAATCCTGTGATATGTACATTGGATTCATGACTGTGCAGCATTTTTA GTTATGTGGTGTTTGGCAGAATGACAATAAGGTTTTCCCCCATTTTGGTTTCAGGAGGACATGAATAGTGTGTTTATTGTAACTCCTCAT ACACTTTTAAAACCAACATCTTTTTTCATAAATGTTGGTAGTGTTTGTCCAGGTACCTTAACTGTAGCTTGTGTAATGTTGATGAATATC TGTATCTTACGGCTTCCATAATGGCTAGTTGATATTCAAAAACCTATTTCTGTGTTTTGAGGGGTGGGGAAAAAAAACACTAAGTGATAA TTTGAAAAAGGCATATTGCTTCCAGATTCTGATGTGTGAGGGAAAATACTGTCACAATGAAAATCTTGACAATTTACTTAACAAGTAACC AGTAGTTCATCAAAACCAACTTGTACAGACTAATAAATCTTTTTCACAGTATTCAGTTTTCTCACCTCTTGCTATTGTATATTGTAGATT >37216_37216_6_HNRNPH3-RAB18_HNRNPH3_chr10_70097090_ENST00000441000_RAB18_chr10_27815757_ENST00000535776_length(amino acids)=138AA_BP=37 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGVDFKVKTISVDGNKAKLAIWENREVDRNEGLKFARKHSMLFIEASAKTCDGV -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for HNRNPH3-RAB18 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for HNRNPH3-RAB18 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for HNRNPH3-RAB18 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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