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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:HNRNPK-NR6A1 (FusionGDB2 ID:37224)

Fusion Gene Summary for HNRNPK-NR6A1

check button Fusion gene summary
Fusion gene informationFusion gene name: HNRNPK-NR6A1
Fusion gene ID: 37224
HgeneTgene
Gene symbol

HNRNPK

NR6A1

Gene ID

3190

2649

Gene nameheterogeneous nuclear ribonucleoprotein Knuclear receptor subfamily 6 group A member 1
SynonymsAUKS|CSBP|HNRPK|TUNPCT150|GCNF|GCNF1|NR61|RTR|hGCNF|hRTR
Cytomap

9q21.32

9q33.3

Type of geneprotein-codingprotein-coding
Descriptionheterogeneous nuclear ribonucleoprotein KdC-stretch binding proteintransformation upregulated nuclear proteinnuclear receptor subfamily 6 group A member 1germ cell nuclear factor variant 1retinoic acid receptor-related testis-associated receptorretinoid receptor-related testis-specific receptor
Modification date2020032920200313
UniProtAcc

P61978

Q15406

Ensembl transtripts involved in fusion geneENST00000351839, ENST00000360384, 
ENST00000376263, ENST00000376264, 
ENST00000376281, 		ENST00000344523, 
ENST00000373584, ENST00000416460, 
ENST00000487099, 
Fusion gene scores* DoF score16 X 18 X 8=230414 X 13 X 6=1092
# samples 1714
** MAII scorelog2(17/2304*10)=-3.76053406530461
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1092*10)=-2.96347412397489
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: HNRNPK [Title/Abstract] AND NR6A1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointHNRNPK(86592604)-NR6A1(127316849), # samples:2
Anticipated loss of major functional domain due to fusion event.HNRNPK-NR6A1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
HNRNPK-NR6A1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
HNRNPK-NR6A1 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across HNRNPK (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NR6A1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A1KZ-01AHNRNPKchr9

86592604

-NR6A1chr9

127316849

-
ChimerDB4SARCTCGA-RN-AAAQ-01AHNRNPKchr9

86592604

-NR6A1chr9

127316849

-


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Fusion Gene ORF analysis for HNRNPK-NR6A1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000351839ENST00000344523HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000351839ENST00000373584HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000351839ENST00000416460HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000360384ENST00000344523HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000360384ENST00000373584HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000360384ENST00000416460HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000376263ENST00000344523HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000376263ENST00000373584HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000376263ENST00000416460HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000376264ENST00000344523HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000376264ENST00000373584HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000376264ENST00000416460HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000376281ENST00000344523HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000376281ENST00000373584HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
5CDS-intronENST00000376281ENST00000416460HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
Frame-shiftENST00000351839ENST00000487099HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
Frame-shiftENST00000376264ENST00000487099HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
Frame-shiftENST00000376281ENST00000487099HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
In-frameENST00000360384ENST00000487099HNRNPKchr9

86592604

-NR6A1chr9

127316849

-
In-frameENST00000376263ENST00000487099HNRNPKchr9

86592604

-NR6A1chr9

127316849

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000376263HNRNPKchr986592604-ENST00000487099NR6A1chr9127316849-71113804451680411
ENST00000360384HNRNPKchr986592604-ENST00000487099NR6A1chr9127316849-70923614261661411

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000376263ENST00000487099HNRNPKchr986592604-NR6A1chr9127316849-0.0011071110.99889296
ENST00000360384ENST00000487099HNRNPKchr986592604-NR6A1chr9127316849-0.001114930.9988851

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Fusion Genomic Features for HNRNPK-NR6A1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for HNRNPK-NR6A1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:86592604/chr9:127316849)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
HNRNPK

P61978

NR6A1

Q15406

FUNCTION: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest. {ECO:0000250, ECO:0000269|PubMed:16360036, ECO:0000269|PubMed:20673990, ECO:0000269|PubMed:22825850}.FUNCTION: Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNR6A1chr9:86592604chr9:127316849ENST0000034452311057_13247480.0DNA bindingNuclear receptor
TgeneNR6A1chr9:86592604chr9:127316849ENST0000037358401057_1320477.0DNA bindingNuclear receptor
TgeneNR6A1chr9:86592604chr9:127316849ENST0000041646001057_1320476.0DNA bindingNuclear receptor
TgeneNR6A1chr9:86592604chr9:127316849ENST0000048709911057_13247481.0DNA bindingNuclear receptor
TgeneNR6A1chr9:86592604chr9:127316849ENST00000344523110249_48047480.0DomainNR LBD
TgeneNR6A1chr9:86592604chr9:127316849ENST00000373584010249_4800477.0DomainNR LBD
TgeneNR6A1chr9:86592604chr9:127316849ENST00000416460010249_4800476.0DomainNR LBD
TgeneNR6A1chr9:86592604chr9:127316849ENST00000487099110249_48047481.0DomainNR LBD
TgeneNR6A1chr9:86592604chr9:127316849ENST0000034452311060_8047480.0Zinc fingerNR C4-type
TgeneNR6A1chr9:86592604chr9:127316849ENST0000034452311096_12047480.0Zinc fingerNR C4-type
TgeneNR6A1chr9:86592604chr9:127316849ENST0000037358401060_800477.0Zinc fingerNR C4-type
TgeneNR6A1chr9:86592604chr9:127316849ENST0000037358401096_1200477.0Zinc fingerNR C4-type
TgeneNR6A1chr9:86592604chr9:127316849ENST0000041646001060_800476.0Zinc fingerNR C4-type
TgeneNR6A1chr9:86592604chr9:127316849ENST0000041646001096_1200476.0Zinc fingerNR C4-type
TgeneNR6A1chr9:86592604chr9:127316849ENST0000048709911060_8047481.0Zinc fingerNR C4-type
TgeneNR6A1chr9:86592604chr9:127316849ENST0000048709911096_12047481.0Zinc fingerNR C4-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316289_29452464.0Compositional biasNote=Poly-Pro
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316310_31552464.0Compositional biasNote=Poly-Pro
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417289_29452464.0Compositional biasNote=Poly-Pro
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417310_31552464.0Compositional biasNote=Poly-Pro
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417289_29452465.0Compositional biasNote=Poly-Pro
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417310_31552465.0Compositional biasNote=Poly-Pro
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417289_29452464.0Compositional biasNote=Poly-Pro
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417310_31552464.0Compositional biasNote=Poly-Pro
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417289_29452465.0Compositional biasNote=Poly-Pro
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417310_31552465.0Compositional biasNote=Poly-Pro
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316144_20952464.0DomainKH 2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316387_45152464.0DomainKH 3
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-31642_10452464.0DomainKH 1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417144_20952464.0DomainKH 2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417387_45152464.0DomainKH 3
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-41742_10452464.0DomainKH 1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417144_20952465.0DomainKH 2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417387_45152465.0DomainKH 3
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-41742_10452465.0DomainKH 1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417144_20952464.0DomainKH 2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417387_45152464.0DomainKH 3
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-41742_10452464.0DomainKH 1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417144_20952465.0DomainKH 2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417387_45152465.0DomainKH 3
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-41742_10452465.0DomainKH 1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316236_27352464.0RegionNote=RNA-binding RGG-box
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316245_32952464.0RegionNote=2 X 6 AA approximate repeats
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-31654_42152464.0RegionNote=2 X 22 AA approximate repeats
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-31659_40752464.0RegionNote=5 X 4 AA repeats of G-X-G-G
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417236_27352464.0RegionNote=RNA-binding RGG-box
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417245_32952464.0RegionNote=2 X 6 AA approximate repeats
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-41754_42152464.0RegionNote=2 X 22 AA approximate repeats
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-41759_40752464.0RegionNote=5 X 4 AA repeats of G-X-G-G
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417236_27352465.0RegionNote=RNA-binding RGG-box
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417245_32952465.0RegionNote=2 X 6 AA approximate repeats
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-41754_42152465.0RegionNote=2 X 22 AA approximate repeats
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-41759_40752465.0RegionNote=5 X 4 AA repeats of G-X-G-G
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417236_27352464.0RegionNote=RNA-binding RGG-box
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417245_32952464.0RegionNote=2 X 6 AA approximate repeats
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-41754_42152464.0RegionNote=2 X 22 AA approximate repeats
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-41759_40752464.0RegionNote=5 X 4 AA repeats of G-X-G-G
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417236_27352465.0RegionNote=RNA-binding RGG-box
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417245_32952465.0RegionNote=2 X 6 AA approximate repeats
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-41754_42152465.0RegionNote=2 X 22 AA approximate repeats
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-41759_40752465.0RegionNote=5 X 4 AA repeats of G-X-G-G
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316245_25052464.0RepeatNote=2-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316257_26052464.0RepeatNote=3-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316267_27052464.0RepeatNote=3-3
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316295_29852464.0RepeatNote=3-4
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316324_32952464.0RepeatNote=2-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316399_42152464.0RepeatNote=1-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316404_40752464.0RepeatNote=3-5
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-31654_7652464.0RepeatNote=1-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-31659_6252464.0RepeatNote=3-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417245_25052464.0RepeatNote=2-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417257_26052464.0RepeatNote=3-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417267_27052464.0RepeatNote=3-3
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417295_29852464.0RepeatNote=3-4
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417324_32952464.0RepeatNote=2-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417399_42152464.0RepeatNote=1-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417404_40752464.0RepeatNote=3-5
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-41754_7652464.0RepeatNote=1-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-41759_6252464.0RepeatNote=3-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417245_25052465.0RepeatNote=2-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417257_26052465.0RepeatNote=3-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417267_27052465.0RepeatNote=3-3
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417295_29852465.0RepeatNote=3-4
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417324_32952465.0RepeatNote=2-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417399_42152465.0RepeatNote=1-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417404_40752465.0RepeatNote=3-5
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-41754_7652465.0RepeatNote=1-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-41759_6252465.0RepeatNote=3-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417245_25052464.0RepeatNote=2-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417257_26052464.0RepeatNote=3-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417267_27052464.0RepeatNote=3-3
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417295_29852464.0RepeatNote=3-4
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417324_32952464.0RepeatNote=2-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417399_42152464.0RepeatNote=1-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417404_40752464.0RepeatNote=3-5
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-41754_7652464.0RepeatNote=1-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-41759_6252464.0RepeatNote=3-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417245_25052465.0RepeatNote=2-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417257_26052465.0RepeatNote=3-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417267_27052465.0RepeatNote=3-3
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417295_29852465.0RepeatNote=3-4
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417324_32952465.0RepeatNote=2-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417399_42152465.0RepeatNote=1-2
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417404_40752465.0RepeatNote=3-5
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-41754_7652465.0RepeatNote=1-1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-41759_6252465.0RepeatNote=3-1


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Fusion Gene Sequence for HNRNPK-NR6A1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>37224_37224_1_HNRNPK-NR6A1_HNRNPK_chr9_86592604_ENST00000360384_NR6A1_chr9_127316849_ENST00000487099_length(transcript)=7092nt_BP=361nt
GGACGCGAGAAGGCGGGGGAGGGGAGCCTGCGCTCGTTTTCTGTCTAGCTCCGACCGGCTGAGGCGGCGCGGCAGCGGAGGGACGGCAGT
CTCGCGCGGCTACTGCAGCACTGGGGTGTCAGTTGTTGGTCCGACCCAGAACGCTTCAGTTCTGCTCTGCAAGGATATATAATAACTGAT
TGGTGTGCCCGTTTAATAAAAGAATATGGAAACTGAACAGCCAGAAGAAACCTTCCCTAACACTGAAACCAATGGTGAATTTGGTAAACG
CCCTGCAGAAGATATGGAAGAGGAACAAGCATTTAAAAGATCTAGAAACACTGATGAGATGGTTGAATTACGCATTCTGCTTCAGAGCAA
GTTTCTGTTTCAGATGATCGGGCTGAACAACGAACCTGTCTCATTTGTGGGGACCGCGCTACAGGCTTGCACTATGGGATCATCTCCTGT
GAGGGCTGCAAAGGGTTTTTCAAGCGGAGCATTTGCAACAAACGGGTATATCGATGCAGTCGTGACAAGAACTGTGTCATGTCTCGGAAG
CAGAGGAACAGGTGCCAGTACTGCCGCCTGCTCAAATGCCTCCAGATGGGGATGAACCGGAAGGCTATCAGAGAAGATGGCATGCCTGGA
GGCCGGAATAAGAGCATTGGGCCAGTCCAGATATCGGAAGAAGAAATCGAAAGGATCATGTCTGGGCAGGAGTTTGAGGAAGAGGCCAAT
CACTGGAGCAACCATGGTGATAGTGACCACAGTTCCCCTGGGAACAGGGCTTCGGAGAGCAACCAGCCCTCACCAGGCTCCACACTGTCT
TCCAGTAGGTCTGTGGAACTGAATGGATTCATGGCCTTCAGGGAACAGTACATGGGAATGTCTGTGCCTCCACATTACCAATATATACCG
CACCTTTTTAGCTATTCTGGCCACTCACCACTTCTGCCCCAACAAGCTCGCAGCCTGGATCCCCAGTCATACAGTCTGATTCACCAGCTG
TTATCAGCCGAGGACCTGGAACCATTGGGCACGCCCATGTTGATTGAAGATGGATACGCTGTGACACAGGCAGAACTATTTGCCCTGCTT
TGCCGCCTGGCCGACGAGCTGCTCTTTAGGCAGATTGCCTGGATCAAGAAACTGCCTTTCTTCTGCGAGCTCTCAATCAAGGATTACACG
TGCCTCTTGAGCTCTACGTGGCAGGAGCTAATCCTGCTGTCTTCCCTCACCGTTTACAGCAAGCAGATCTTTGGGGAACTGGCTGATGTC
ACTGCCAAGTACTCGCCCTCCGATGAAGAACTACACAGATTTAGTGATGAAGGGATGGAGGTGATCGAGCGGCTCATCTACCTCTATCAC
AAGTTCCATCAGCTAAAGGTCAGCAACGAGGAGTATGCTTGCATGAAAGCAATTAACTTCCTAAATCAAGATATCAGGGGTCTGACCAGT
GCCTCACAGCTGGAACAATTGAATAAACGATACTGGTACATTTGCCAGGATTTTACTGAATATAAATACACACATCAGCCGAACCGCTTT
CCTGATCTCATGATGTGCTTACCTGAGATTCGATATATTGCAGGAAAGATGGTGAATGTGCCCCTGGAGCAGCTGCCCCTCCTCTTTAAG
GTGGTGCTGCATTCCTGCAAGACCAGTGTGGGCAAGGAATGACCTGTTCCAGGCGCCCTCCTCAGGCCAACCACAGCGTCTTGGGTGGGC
AGGACAGGCTCTGGAGGGAAAAGCCAGAGAGACCAAGATGGAGGCTGTGGAGCAGCATTTCCCGTTGCCTCCATAGCAAGAAGAGTTTTT
GTTTGTTTGTCTGTTTTTTTAACCTCATTTTTCTATATATTTATTTCACGACAGAGTTGAATGTATGGCCTTCAACATGATGCACATGCT
TTTGTGTGAATGCAGCCAATGCATTTTCTTACAGTTTACAGAATGTGAAGATGTTTAATGTTACAGTGTTGTCATTGTTTAGAAATAGTT
CTTTTGTATTTTGAGGGAGAGGGTGGGATGGGGCTAAGATGACTATTTCCATAATGTTGACAAAGATGACTACCTCAATGGAAATGGGGG
GTGTGGCCATCCCTACTTTTTCCACATTTTCTCAGCAGACTCATACATTTGTCTGTCAGAGAGCAAATTGCCTTTTTTAGCCACAGAATT
GCCAGATAAAACGGCACACTGTAAGGGGGCAAAGTGTTGTTAGGAGATTCACTAAGCAAGGTTGGTGAGACGGCAACAGGGTAGGAGGTG
AGGATTGAGCCACGTCCTTTCCTTGGAAAGCGTGAAAATTAAGAGAGTAGGGCACAGTGACCATATTTAAGGCAGGTGTCCTTCCACCCA
ACAAGTCCTAAGGGCAGAAGAATTTCTGTTCTCACACCTTGCTGCCCCCCTTACCCCTGCACCACCATCATTGTCTACCACTGCGAACTT
TCCATCTAGGCAAAGTCCTGGCAATCACTTGATCCACAGGACTCGCCTCCCAGCTCCCTCGGGGCCCCCAGCTACCTAGTTTCCTTACCT
GGATCTCCTGAGGCCCACCTTCCTCCTTCCCACTCCCTTACACATTTGACTTCCTATTGGCCCTTTGAAAAACCAGCTGAGCAGAATGCC
ATGTTCTGAAGCCTGGTGCCCACTACTGATTTATTCTCCTTTCACCTTGTTTTCTTCAAAGGGTAGTAGGGCAAGGCCAGACTGCAAAAA
GAATAGACACTCCCCTTTTGAAATCTGTTCCTCTCCCCTCCCCTTCCTACCGCACCCTCAGGTCTAAATCCGAAAACTTCAGGCTTTTTT
AAACAATGAGAAGGACCATTCACCTGTCTGCTGACCAGAAATGTTGCCCCTAAGTTCTTCTCCAAGTTCTCCTTTTCTCTCCAGAGTGAG
ACCAGTTTTCCTCAGGGACCCAGGACACAAAGCCCAAGGCCCAGAGTGGCTCAGCTGCCCCTTACTTCAGCAGTGGACTGGCCAGCCAAG
GCCTGGAGGGCTGGAGCCAGAAGCACCTGGAAGGGAAGGGGGGCTTTAAACTACCTCAGGTTCCTAATGGCCCGGCTGCTACCTCTGCAG
ACATGGCCTGGACTCCTTGACCTCTCACTACCTGCCCCACCTTATCCCAGGACGTGTTCCTTACCCTCTTGACTTTGGCCAGCGCTACAC
CAGGTCTGTCTTTGAACTCTTTCAGGTGCTTGTCCTGCCTACACCCAGGTATCTTTCACAGCCAGTGTGGCAAGCAGACCACTTAGTTGG
CTGCATGCCTGGGTAGGTTGGAAGGGCCCACGGCACCTTCTTCTGCCTATTTAGTCAAAGGCTGTTTGCTGTCTCCTCAACTCAACCTAG
TAAAGCTACCCAGGAGGGCACCACGTCGTGTGCATACTGGGTAGTCCATGTCTGATTGTAATTGTTTCTTTCTGGTGAAATGTTACGGGT
ACCAGCAGAGTGATGATTTTGGCCCTTGATGGATCTAAAACTCGGAACATTACTCCTCAATGCCGTTTCCCCAGTTGCTCTGAGAAGGAA
GAGACATGTTCCTCAGGAAAAGCTCCAGCTAGCATGTTTTTCACGTCAGTGGGAAGATTCTTGTGTGTTCGTGTGTATCTGTTTATTTCT
AAGTTCACGATACTTGTTCCCCTGAATTTTATTTAACCAACTAGATCACATTCTTTGGCCACAGGTCAGACTCTGAGCTGCTTTCCTCCA
GATCGGGAAGGAGACACATATCACAGATGCCTTCTCTAAGACAGCTCCTGTGTACAGCATCGTTCTTTGCTGAGGCCTCTATCTGTCCAA
TTATTATTTTTGAAATTGCTTTTCAAATTAAACATTTTACCCGTTGTGTTGGGTGTCAAAAGAAATTGCTCTCTGATGAGGCAAGAACAT
GTCTCTCCAACAACGTAGTATTGAACAGAGCAAGTTGTTAATTTGTGGAGTAGGGGAAAGGTTCTGCAAGTTGCCATTGTACAAATCCAG
TTTTACAAATGTTTGCAGCAGATTCCACAGAACAAAGAGCCCATTCATTGCCGAGAGCCCTGCAGAATCTCAGAGCAAAGTGGCTGTGTG
TTCCGAGCCGGAGCCTGACCTGTGGACCGTCTTTAATGTCTTCTGCACCAGTCCTTTTATGACGTGGGCTTTTTTTAAACAGGGTAAAGT
GAATGTGTTGCATTGCAAACTCAGGTATTATGAGGAGAAGGTAGGAGTGTAGCTAGCAGCGTGGAGACATTAGGTCAGCCACTAGATGTA
TTTGTGAATTTGGTTTGAAGGACACGGAGAAAGGTTGGAGGGGAGGTTTGGTGTGTTTGTTTTTTGCTTTCTTCCCCATAATGTTTGGTT
AACAGGTAGCCTTTTTGCGAGTGGAAGGAGAGAAAAGTTGTGCATGTTTTCTCTAATTTCTCTTTCTGCCCTCTCTCTGATCCCCAACCA
CCAAAAGCACTCACTTTGAGTGAGGATTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGGCGGAGTCTCGCTCTGTCGCTCAGGCTGGAGT
GCAGTGGTGCGATCTTGGCTCACTGCAAGCTCCGCCTCCCGGGTTCATGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAG
GCGCCCGCCACCACACCCGGCTAACTTTTTTTGTATTTTTAGTAGAAACATTGTTTCACCACGTTAGCCAGGATGGTCTCCATCTCCTGA
CCTCGTGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCACCCAGCCGAGTGAGAATTTTTATGCCATA
AAAATACGACTCTGAAAGCTACATGGAAAAGGAGAATCCCACCTCCTTGCACTACATTGAAACATGCAAGCCTTTCCCTCCCTCTCCTTT
TTGATGTTTTCTTGTCCCAAGACAAAAGTTTGGCATCTTGGAACTTATTCATGCTCTCTGGCTGCCTTTGTAGACTTTTGGAGTCCTTTG
CAAGGTTTGGTGGTCTCGTCGTTAATCTGGAGAAATTCCCCAGAATCTGTCTCAAAGCGCTCAACCTGGCTCAGAGGACACCCAGCCCCT
ATGCCCCACTCACAAGAGAGGTGGGCAAGCCCCCAGGGATAGGAGGAAGTAAGCAGGATCCTCCCTGTCCTGTTTCCCAGAACCAGAGCA
AGGAATGGGGAATCCTAAGGGTTTCTGTGGCATCACTGAATGTCACCCACTCCACATCAACCTGCCTCTCACCTGCCACCCTTTTTCAGG
GAGGTGAGTACCTGCCATGGTCACTGTTACCAGATCCTTAAAATCCTGGGCTCTGAGCTAGGTGCATTGCTCTGTTACCCATTTCCTACA
TTTGTTTGTTTGTTCTTGATTTCCTGGGGGAATGGGACTGATGGAGACAGACAAACCCACTGTGGGCAGCATCTAAGCCATGTCCAAGGT
TGGTCGAATTAAGGGAACCCTGGCCTCTCAGCAGGACAGAAAGCTGAGCTGTGGTTCCAGGCCCTCCTCTCTGGGCCCCTGGTGTGTATC
TTTTTTCCTTGTTGCTTTTGAAATTTTTGCAATTATTTTAAGAATCCAGTCTTTCAGACCAGCCCTTTTATTAAGCTTTGAATTTTTAAT
TGATTTTTTTAAAGTAAAAAAAAAAAAAACCCAAAAAACAAACAAAATTTAACAAAAAAATCCGCTACTCTTACTCCCCTGCCTCCCCCT
ACCCCAGCCCATGAGAGTTCCCTTGCACTCCCCTCTGCCTTTGCAACTGATCATCCTCCCTTTCTCCTTGGCTTGAAGCATCTATGTCCA
GTATCTGTGAAATGATGTTTTATCTGTGTGTCAGGATGAGAAACGGCAGTCATTCCACCAAGTGTTGGAAACTGGTTAGCCTGGAGACAA
GGGTTTCTGGGGCCACAGCTCAGGGATGTGTATTTAATTACAGGATCCCCAGAAACTCCTCTCTAGGCTGCCACAGCAACATTTTTTCTG
GGCTTGGGAGCCATACCTGAACTGTTTCCTCCAAGGCGGGAACTCCAGAGAGCCTGCCAAGTCTGGAGCAAGCTGGGGCTTCTGCTTTGG
CCAGACCTGGGCCACCATGAGACTTGAAGGCTTCTAGCTGTCCTACGACACGAGCCACGGTGGCCCTGCCTCTCCCCGCTCATAGAAGCC
TGGTCCCTCTGTCTAGCCCAGTTCCCATCTAGCATCCGTCTTCTGGGCCTGAAGCCCTAAATGGACCACAGCCTGCACAGGAATCAACTG
TAGGCTCAAAGGGAGGCGGTGAGTAAGGTCAGAGCCTGCTCCAAGCCCAAGAACAAAAGTTGTGTTATGGGTGGAGGCTAGTCCCCCAGA
TCTAGCCCTGCCGTCTTTGCCCTTTAATGACCATTGTTTTCTTTCTCTAAAATGTCTTGTAATAGGTGATAATGTTGTTGATTCAAATTT
CCATGAAAAAGAAAAAAAAAACTACCTCTTAAGCGACATCCTGGTCGATTCCTCTCTGAGGAATCCTGTGGGAAAAGAATACTGTAGCTC
CTGCTCTGTTTACATGTTTCTGTCGGGAAAGAAGCCCCGCCTGCCCTGGGGTGTTGGTGTTTTTGTCTGTGTTGCCATCCCAGGTCTGCC
ATAGGGGCTGGTGGCTGCATTGTGATGTCTGGGCTGTGTCTGGGGATTCCTTCCCACCTACCCAGCCAGGGACTAGTCACCCCCCTGAAG
AGGCCTCCATTTCCTTCCTGTGCTCCAGGGCATAGGGAGCACCACTCCCACAGACACCACCTTTAAGGGCTCTAGTGGCACACACATCCA
CGAGCCTACCCCCAGGTTACCTGCCCTAGGTCCACCTCCACCCACAGTCCTGTGTGTAGGAATCGAGGAAACGGGATGTCCCTGAGCCCT
TGTCTCCAAAGGGCCGGCCAAGGGCTGCCCGCCAGCCTGACTCCATCAACCCTCCATGACCAAATGATAGCTGGCGGGCTCTGCAGGCTA
CCCAGGCCCTCTGCTACCTCCCACCCTGCCAGCTGGCAAGGGATGGGCCCTGTTCTGTGAATTGACTACCTGTGGAAATGTGACCAATTA

>37224_37224_1_HNRNPK-NR6A1_HNRNPK_chr9_86592604_ENST00000360384_NR6A1_chr9_127316849_ENST00000487099_length(amino acids)=411AA_BP=
MHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSG
QEFEEEANHWSNHGDSDHSSPGNRASESNQPSPGSTLSSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQQARSLDPQ
SYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQ
IFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYK

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>37224_37224_2_HNRNPK-NR6A1_HNRNPK_chr9_86592604_ENST00000376263_NR6A1_chr9_127316849_ENST00000487099_length(transcript)=7111nt_BP=380nt
TAGGGCGCGACGGCGGGGAGGACGCGAGAAGGCGGGGGAGGGGAGCCTGCGCTCGTTTTCTGTCTAGCTCCGACCGGCTGAGGCGGCGCG
GCAGCGGAGGGACGGCAGTCTCGCGCGGCTACTGCAGCACTGGGGTGTCAGTTGTTGGTCCGACCCAGAACGCTTCAGTTCTGCTCTGCA
AGGATATATAATAACTGATTGGTGTGCCCGTTTAATAAAAGAATATGGAAACTGAACAGCCAGAAGAAACCTTCCCTAACACTGAAACCA
ATGGTGAATTTGGTAAACGCCCTGCAGAAGATATGGAAGAGGAACAAGCATTTAAAAGATCTAGAAACACTGATGAGATGGTTGAATTAC
GCATTCTGCTTCAGAGCAAGTTTCTGTTTCAGATGATCGGGCTGAACAACGAACCTGTCTCATTTGTGGGGACCGCGCTACAGGCTTGCA
CTATGGGATCATCTCCTGTGAGGGCTGCAAAGGGTTTTTCAAGCGGAGCATTTGCAACAAACGGGTATATCGATGCAGTCGTGACAAGAA
CTGTGTCATGTCTCGGAAGCAGAGGAACAGGTGCCAGTACTGCCGCCTGCTCAAATGCCTCCAGATGGGGATGAACCGGAAGGCTATCAG
AGAAGATGGCATGCCTGGAGGCCGGAATAAGAGCATTGGGCCAGTCCAGATATCGGAAGAAGAAATCGAAAGGATCATGTCTGGGCAGGA
GTTTGAGGAAGAGGCCAATCACTGGAGCAACCATGGTGATAGTGACCACAGTTCCCCTGGGAACAGGGCTTCGGAGAGCAACCAGCCCTC
ACCAGGCTCCACACTGTCTTCCAGTAGGTCTGTGGAACTGAATGGATTCATGGCCTTCAGGGAACAGTACATGGGAATGTCTGTGCCTCC
ACATTACCAATATATACCGCACCTTTTTAGCTATTCTGGCCACTCACCACTTCTGCCCCAACAAGCTCGCAGCCTGGATCCCCAGTCATA
CAGTCTGATTCACCAGCTGTTATCAGCCGAGGACCTGGAACCATTGGGCACGCCCATGTTGATTGAAGATGGATACGCTGTGACACAGGC
AGAACTATTTGCCCTGCTTTGCCGCCTGGCCGACGAGCTGCTCTTTAGGCAGATTGCCTGGATCAAGAAACTGCCTTTCTTCTGCGAGCT
CTCAATCAAGGATTACACGTGCCTCTTGAGCTCTACGTGGCAGGAGCTAATCCTGCTGTCTTCCCTCACCGTTTACAGCAAGCAGATCTT
TGGGGAACTGGCTGATGTCACTGCCAAGTACTCGCCCTCCGATGAAGAACTACACAGATTTAGTGATGAAGGGATGGAGGTGATCGAGCG
GCTCATCTACCTCTATCACAAGTTCCATCAGCTAAAGGTCAGCAACGAGGAGTATGCTTGCATGAAAGCAATTAACTTCCTAAATCAAGA
TATCAGGGGTCTGACCAGTGCCTCACAGCTGGAACAATTGAATAAACGATACTGGTACATTTGCCAGGATTTTACTGAATATAAATACAC
ACATCAGCCGAACCGCTTTCCTGATCTCATGATGTGCTTACCTGAGATTCGATATATTGCAGGAAAGATGGTGAATGTGCCCCTGGAGCA
GCTGCCCCTCCTCTTTAAGGTGGTGCTGCATTCCTGCAAGACCAGTGTGGGCAAGGAATGACCTGTTCCAGGCGCCCTCCTCAGGCCAAC
CACAGCGTCTTGGGTGGGCAGGACAGGCTCTGGAGGGAAAAGCCAGAGAGACCAAGATGGAGGCTGTGGAGCAGCATTTCCCGTTGCCTC
CATAGCAAGAAGAGTTTTTGTTTGTTTGTCTGTTTTTTTAACCTCATTTTTCTATATATTTATTTCACGACAGAGTTGAATGTATGGCCT
TCAACATGATGCACATGCTTTTGTGTGAATGCAGCCAATGCATTTTCTTACAGTTTACAGAATGTGAAGATGTTTAATGTTACAGTGTTG
TCATTGTTTAGAAATAGTTCTTTTGTATTTTGAGGGAGAGGGTGGGATGGGGCTAAGATGACTATTTCCATAATGTTGACAAAGATGACT
ACCTCAATGGAAATGGGGGGTGTGGCCATCCCTACTTTTTCCACATTTTCTCAGCAGACTCATACATTTGTCTGTCAGAGAGCAAATTGC
CTTTTTTAGCCACAGAATTGCCAGATAAAACGGCACACTGTAAGGGGGCAAAGTGTTGTTAGGAGATTCACTAAGCAAGGTTGGTGAGAC
GGCAACAGGGTAGGAGGTGAGGATTGAGCCACGTCCTTTCCTTGGAAAGCGTGAAAATTAAGAGAGTAGGGCACAGTGACCATATTTAAG
GCAGGTGTCCTTCCACCCAACAAGTCCTAAGGGCAGAAGAATTTCTGTTCTCACACCTTGCTGCCCCCCTTACCCCTGCACCACCATCAT
TGTCTACCACTGCGAACTTTCCATCTAGGCAAAGTCCTGGCAATCACTTGATCCACAGGACTCGCCTCCCAGCTCCCTCGGGGCCCCCAG
CTACCTAGTTTCCTTACCTGGATCTCCTGAGGCCCACCTTCCTCCTTCCCACTCCCTTACACATTTGACTTCCTATTGGCCCTTTGAAAA
ACCAGCTGAGCAGAATGCCATGTTCTGAAGCCTGGTGCCCACTACTGATTTATTCTCCTTTCACCTTGTTTTCTTCAAAGGGTAGTAGGG
CAAGGCCAGACTGCAAAAAGAATAGACACTCCCCTTTTGAAATCTGTTCCTCTCCCCTCCCCTTCCTACCGCACCCTCAGGTCTAAATCC
GAAAACTTCAGGCTTTTTTAAACAATGAGAAGGACCATTCACCTGTCTGCTGACCAGAAATGTTGCCCCTAAGTTCTTCTCCAAGTTCTC
CTTTTCTCTCCAGAGTGAGACCAGTTTTCCTCAGGGACCCAGGACACAAAGCCCAAGGCCCAGAGTGGCTCAGCTGCCCCTTACTTCAGC
AGTGGACTGGCCAGCCAAGGCCTGGAGGGCTGGAGCCAGAAGCACCTGGAAGGGAAGGGGGGCTTTAAACTACCTCAGGTTCCTAATGGC
CCGGCTGCTACCTCTGCAGACATGGCCTGGACTCCTTGACCTCTCACTACCTGCCCCACCTTATCCCAGGACGTGTTCCTTACCCTCTTG
ACTTTGGCCAGCGCTACACCAGGTCTGTCTTTGAACTCTTTCAGGTGCTTGTCCTGCCTACACCCAGGTATCTTTCACAGCCAGTGTGGC
AAGCAGACCACTTAGTTGGCTGCATGCCTGGGTAGGTTGGAAGGGCCCACGGCACCTTCTTCTGCCTATTTAGTCAAAGGCTGTTTGCTG
TCTCCTCAACTCAACCTAGTAAAGCTACCCAGGAGGGCACCACGTCGTGTGCATACTGGGTAGTCCATGTCTGATTGTAATTGTTTCTTT
CTGGTGAAATGTTACGGGTACCAGCAGAGTGATGATTTTGGCCCTTGATGGATCTAAAACTCGGAACATTACTCCTCAATGCCGTTTCCC
CAGTTGCTCTGAGAAGGAAGAGACATGTTCCTCAGGAAAAGCTCCAGCTAGCATGTTTTTCACGTCAGTGGGAAGATTCTTGTGTGTTCG
TGTGTATCTGTTTATTTCTAAGTTCACGATACTTGTTCCCCTGAATTTTATTTAACCAACTAGATCACATTCTTTGGCCACAGGTCAGAC
TCTGAGCTGCTTTCCTCCAGATCGGGAAGGAGACACATATCACAGATGCCTTCTCTAAGACAGCTCCTGTGTACAGCATCGTTCTTTGCT
GAGGCCTCTATCTGTCCAATTATTATTTTTGAAATTGCTTTTCAAATTAAACATTTTACCCGTTGTGTTGGGTGTCAAAAGAAATTGCTC
TCTGATGAGGCAAGAACATGTCTCTCCAACAACGTAGTATTGAACAGAGCAAGTTGTTAATTTGTGGAGTAGGGGAAAGGTTCTGCAAGT
TGCCATTGTACAAATCCAGTTTTACAAATGTTTGCAGCAGATTCCACAGAACAAAGAGCCCATTCATTGCCGAGAGCCCTGCAGAATCTC
AGAGCAAAGTGGCTGTGTGTTCCGAGCCGGAGCCTGACCTGTGGACCGTCTTTAATGTCTTCTGCACCAGTCCTTTTATGACGTGGGCTT
TTTTTAAACAGGGTAAAGTGAATGTGTTGCATTGCAAACTCAGGTATTATGAGGAGAAGGTAGGAGTGTAGCTAGCAGCGTGGAGACATT
AGGTCAGCCACTAGATGTATTTGTGAATTTGGTTTGAAGGACACGGAGAAAGGTTGGAGGGGAGGTTTGGTGTGTTTGTTTTTTGCTTTC
TTCCCCATAATGTTTGGTTAACAGGTAGCCTTTTTGCGAGTGGAAGGAGAGAAAAGTTGTGCATGTTTTCTCTAATTTCTCTTTCTGCCC
TCTCTCTGATCCCCAACCACCAAAAGCACTCACTTTGAGTGAGGATTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGGCGGAGTCTCGCT
CTGTCGCTCAGGCTGGAGTGCAGTGGTGCGATCTTGGCTCACTGCAAGCTCCGCCTCCCGGGTTCATGCCATTCTCCTGCCTCAGCCTCC
TGAGTAGCTGGGACTACAGGCGCCCGCCACCACACCCGGCTAACTTTTTTTGTATTTTTAGTAGAAACATTGTTTCACCACGTTAGCCAG
GATGGTCTCCATCTCCTGACCTCGTGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCACCCAGCCGAG
TGAGAATTTTTATGCCATAAAAATACGACTCTGAAAGCTACATGGAAAAGGAGAATCCCACCTCCTTGCACTACATTGAAACATGCAAGC
CTTTCCCTCCCTCTCCTTTTTGATGTTTTCTTGTCCCAAGACAAAAGTTTGGCATCTTGGAACTTATTCATGCTCTCTGGCTGCCTTTGT
AGACTTTTGGAGTCCTTTGCAAGGTTTGGTGGTCTCGTCGTTAATCTGGAGAAATTCCCCAGAATCTGTCTCAAAGCGCTCAACCTGGCT
CAGAGGACACCCAGCCCCTATGCCCCACTCACAAGAGAGGTGGGCAAGCCCCCAGGGATAGGAGGAAGTAAGCAGGATCCTCCCTGTCCT
GTTTCCCAGAACCAGAGCAAGGAATGGGGAATCCTAAGGGTTTCTGTGGCATCACTGAATGTCACCCACTCCACATCAACCTGCCTCTCA
CCTGCCACCCTTTTTCAGGGAGGTGAGTACCTGCCATGGTCACTGTTACCAGATCCTTAAAATCCTGGGCTCTGAGCTAGGTGCATTGCT
CTGTTACCCATTTCCTACATTTGTTTGTTTGTTCTTGATTTCCTGGGGGAATGGGACTGATGGAGACAGACAAACCCACTGTGGGCAGCA
TCTAAGCCATGTCCAAGGTTGGTCGAATTAAGGGAACCCTGGCCTCTCAGCAGGACAGAAAGCTGAGCTGTGGTTCCAGGCCCTCCTCTC
TGGGCCCCTGGTGTGTATCTTTTTTCCTTGTTGCTTTTGAAATTTTTGCAATTATTTTAAGAATCCAGTCTTTCAGACCAGCCCTTTTAT
TAAGCTTTGAATTTTTAATTGATTTTTTTAAAGTAAAAAAAAAAAAAACCCAAAAAACAAACAAAATTTAACAAAAAAATCCGCTACTCT
TACTCCCCTGCCTCCCCCTACCCCAGCCCATGAGAGTTCCCTTGCACTCCCCTCTGCCTTTGCAACTGATCATCCTCCCTTTCTCCTTGG
CTTGAAGCATCTATGTCCAGTATCTGTGAAATGATGTTTTATCTGTGTGTCAGGATGAGAAACGGCAGTCATTCCACCAAGTGTTGGAAA
CTGGTTAGCCTGGAGACAAGGGTTTCTGGGGCCACAGCTCAGGGATGTGTATTTAATTACAGGATCCCCAGAAACTCCTCTCTAGGCTGC
CACAGCAACATTTTTTCTGGGCTTGGGAGCCATACCTGAACTGTTTCCTCCAAGGCGGGAACTCCAGAGAGCCTGCCAAGTCTGGAGCAA
GCTGGGGCTTCTGCTTTGGCCAGACCTGGGCCACCATGAGACTTGAAGGCTTCTAGCTGTCCTACGACACGAGCCACGGTGGCCCTGCCT
CTCCCCGCTCATAGAAGCCTGGTCCCTCTGTCTAGCCCAGTTCCCATCTAGCATCCGTCTTCTGGGCCTGAAGCCCTAAATGGACCACAG
CCTGCACAGGAATCAACTGTAGGCTCAAAGGGAGGCGGTGAGTAAGGTCAGAGCCTGCTCCAAGCCCAAGAACAAAAGTTGTGTTATGGG
TGGAGGCTAGTCCCCCAGATCTAGCCCTGCCGTCTTTGCCCTTTAATGACCATTGTTTTCTTTCTCTAAAATGTCTTGTAATAGGTGATA
ATGTTGTTGATTCAAATTTCCATGAAAAAGAAAAAAAAAACTACCTCTTAAGCGACATCCTGGTCGATTCCTCTCTGAGGAATCCTGTGG
GAAAAGAATACTGTAGCTCCTGCTCTGTTTACATGTTTCTGTCGGGAAAGAAGCCCCGCCTGCCCTGGGGTGTTGGTGTTTTTGTCTGTG
TTGCCATCCCAGGTCTGCCATAGGGGCTGGTGGCTGCATTGTGATGTCTGGGCTGTGTCTGGGGATTCCTTCCCACCTACCCAGCCAGGG
ACTAGTCACCCCCCTGAAGAGGCCTCCATTTCCTTCCTGTGCTCCAGGGCATAGGGAGCACCACTCCCACAGACACCACCTTTAAGGGCT
CTAGTGGCACACACATCCACGAGCCTACCCCCAGGTTACCTGCCCTAGGTCCACCTCCACCCACAGTCCTGTGTGTAGGAATCGAGGAAA
CGGGATGTCCCTGAGCCCTTGTCTCCAAAGGGCCGGCCAAGGGCTGCCCGCCAGCCTGACTCCATCAACCCTCCATGACCAAATGATAGC
TGGCGGGCTCTGCAGGCTACCCAGGCCCTCTGCTACCTCCCACCCTGCCAGCTGGCAAGGGATGGGCCCTGTTCTGTGAATTGACTACCT
GTGGAAATGTGACCAATTAGTGTGAAATGCATGTTTAGCAAGTGTTAGGTACTGTATTTGAACCAATAAATGTGAATCCTTCTGCACATG

>37224_37224_2_HNRNPK-NR6A1_HNRNPK_chr9_86592604_ENST00000376263_NR6A1_chr9_127316849_ENST00000487099_length(amino acids)=411AA_BP=
MHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSG
QEFEEEANHWSNHGDSDHSSPGNRASESNQPSPGSTLSSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQQARSLDPQ
SYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQ
IFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYK

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Fusion Gene PPI Analysis for HNRNPK-NR6A1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-31635_19752.0464.0ASFV p30
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-41735_19752.0464.0ASFV p30
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-41735_19752.0465.0ASFV p30
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-41735_19752.0464.0ASFV p30
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-41735_19752.0465.0ASFV p30
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000351839-316209_33752.0464.0ZIK1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000360384-417209_33752.0464.0ZIK1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376263-417209_33752.0465.0ZIK1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376264-417209_33752.0464.0ZIK1
HgeneHNRNPKchr9:86592604chr9:127316849ENST00000376281-417209_33752.0465.0ZIK1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for HNRNPK-NR6A1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for HNRNPK-NR6A1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource