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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:HNRNPUL1-BRSK1 (FusionGDB2 ID:37305)

Fusion Gene Summary for HNRNPUL1-BRSK1

check button Fusion gene summary
Fusion gene informationFusion gene name: HNRNPUL1-BRSK1
Fusion gene ID: 37305
HgeneTgene
Gene symbol

HNRNPUL1

BRSK1

Gene ID

11100

84446

Gene nameheterogeneous nuclear ribonucleoprotein U like 1BR serine/threonine kinase 1
SynonymsE1B-AP5|E1BAP5|HNRPUL1hSAD1
Cytomap

19q13.2

19q13.42

Type of geneprotein-codingprotein-coding
Descriptionheterogeneous nuclear ribonucleoprotein U-like protein 1E1B 55kDa associated protein 5E1B-55 kDa-associated protein 5adenovirus early region 1B-associated protein 5serine/threonine-protein kinase BRSK1BR serine/threonine-protein kinase 1SAD1 homologSAD1 kinaseSadB kinase short isoformbrain-selective kinase 1brain-specific serine/threonine-protein kinase 1protein kinase SAD1Aserine/threonine-protein kinase SA
Modification date2020032720200313
UniProtAcc

Q9BUJ2

Q8TDC3

Ensembl transtripts involved in fusion geneENST00000263367, ENST00000352456, 
ENST00000392006, ENST00000593587, 
ENST00000595018, ENST00000602130, 
ENST00000378215, ENST00000594207, 
ENST00000326848, ENST00000588584, 
ENST00000309383, ENST00000585418, 
ENST00000590333, 
Fusion gene scores* DoF score18 X 14 X 12=30245 X 5 X 4=100
# samples 205
** MAII scorelog2(20/3024*10)=-3.91838623444635
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: HNRNPUL1 [Title/Abstract] AND BRSK1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointHNRNPUL1(41787180)-BRSK1(55795889), # samples:1
Anticipated loss of major functional domain due to fusion event.HNRNPUL1-BRSK1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
HNRNPUL1-BRSK1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
HNRNPUL1-BRSK1 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
HNRNPUL1-BRSK1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneBRSK1

GO:0000086

G2/M transition of mitotic cell cycle

15150265

TgeneBRSK1

GO:0006468

protein phosphorylation

15150265

TgeneBRSK1

GO:0006974

cellular response to DNA damage stimulus

15150265

TgeneBRSK1

GO:0007095

mitotic G2 DNA damage checkpoint

15150265

TgeneBRSK1

GO:0009411

response to UV

15150265

TgeneBRSK1

GO:0010212

response to ionizing radiation

15150265

TgeneBRSK1

GO:0018105

peptidyl-serine phosphorylation

15150265


check buttonFusion gene breakpoints across HNRNPUL1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BRSK1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-C5-A907-01AHNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+


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Fusion Gene ORF analysis for HNRNPUL1-BRSK1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000263367ENST00000326848HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
5CDS-intronENST00000263367ENST00000588584HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
5CDS-intronENST00000352456ENST00000326848HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
5CDS-intronENST00000352456ENST00000588584HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
5CDS-intronENST00000392006ENST00000326848HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
5CDS-intronENST00000392006ENST00000588584HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
5CDS-intronENST00000593587ENST00000326848HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
5CDS-intronENST00000593587ENST00000588584HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
5CDS-intronENST00000595018ENST00000326848HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
5CDS-intronENST00000595018ENST00000588584HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
5CDS-intronENST00000602130ENST00000326848HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
5CDS-intronENST00000602130ENST00000588584HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
Frame-shiftENST00000263367ENST00000309383HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
Frame-shiftENST00000263367ENST00000585418HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
Frame-shiftENST00000352456ENST00000309383HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
Frame-shiftENST00000352456ENST00000585418HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
Frame-shiftENST00000392006ENST00000309383HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
Frame-shiftENST00000392006ENST00000585418HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
Frame-shiftENST00000593587ENST00000309383HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
Frame-shiftENST00000593587ENST00000585418HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
Frame-shiftENST00000595018ENST00000309383HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
Frame-shiftENST00000595018ENST00000585418HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
Frame-shiftENST00000602130ENST00000309383HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
Frame-shiftENST00000602130ENST00000585418HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
In-frameENST00000263367ENST00000590333HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
In-frameENST00000352456ENST00000590333HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
In-frameENST00000392006ENST00000590333HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
In-frameENST00000593587ENST00000590333HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
In-frameENST00000595018ENST00000590333HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
In-frameENST00000602130ENST00000590333HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
intron-3CDSENST00000378215ENST00000309383HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
intron-3CDSENST00000378215ENST00000585418HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
intron-3CDSENST00000378215ENST00000590333HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
intron-3CDSENST00000594207ENST00000309383HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
intron-3CDSENST00000594207ENST00000585418HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
intron-3CDSENST00000594207ENST00000590333HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
intron-intronENST00000378215ENST00000326848HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
intron-intronENST00000378215ENST00000588584HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
intron-intronENST00000594207ENST00000326848HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+
intron-intronENST00000594207ENST00000588584HNRNPUL1chr19

41787180

+BRSK1chr19

55795889

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000352456HNRNPUL1chr1941787180+ENST00000590333BRSK1chr1955795889+35157911130491012
ENST00000595018HNRNPUL1chr1941787180+ENST00000590333BRSK1chr1955795889+3492768453026993
ENST00000392006HNRNPUL1chr1941787180+ENST00000590333BRSK1chr1955795889+389611724434301128
ENST00000602130HNRNPUL1chr1941787180+ENST00000590333BRSK1chr1955795889+377610525333101085
ENST00000593587HNRNPUL1chr1941787180+ENST00000590333BRSK1chr1955795889+3517793943051985
ENST00000263367HNRNPUL1chr1941787180+ENST00000590333BRSK1chr1955795889+365092616131841007

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000352456ENST00000590333HNRNPUL1chr1941787180+BRSK1chr1955795889+0.0021457380.9978543
ENST00000595018ENST00000590333HNRNPUL1chr1941787180+BRSK1chr1955795889+0.0022564640.9977436
ENST00000392006ENST00000590333HNRNPUL1chr1941787180+BRSK1chr1955795889+0.0033780140.99662197
ENST00000602130ENST00000590333HNRNPUL1chr1941787180+BRSK1chr1955795889+0.0032458430.9967541
ENST00000593587ENST00000590333HNRNPUL1chr1941787180+BRSK1chr1955795889+0.0025108660.9974891
ENST00000263367ENST00000590333HNRNPUL1chr1941787180+BRSK1chr1955795889+0.002376960.997623

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Fusion Genomic Features for HNRNPUL1-BRSK1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
HNRNPUL1chr1941787180+BRSK1chr1955795888+3.15E-050.9999684
HNRNPUL1chr1941787180+BRSK1chr1955795888+3.15E-050.9999684

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for HNRNPUL1-BRSK1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:41787180/chr19:55795889)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
HNRNPUL1

Q9BUJ2

BRSK1

Q8TDC3

FUNCTION: Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro. {ECO:0000269|PubMed:12489984, ECO:0000269|PubMed:9733834}.FUNCTION: Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Thr-529' and 'Ser-579'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in postmitotic neurons, leading to down-regulate WEE1 activity in polarized neurons. In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possibly by phosphorylating RIMS1. Also acts as a positive regulator of centrosome duplication by mediating phosphorylation of gamma-tubulin (TUBG1 and TUBG2) at 'Ser-131', leading to translocation of gamma-tubulin and its associated proteins to the centrosome. Involved in the UV-induced DNA damage checkpoint response, probably by inhibiting CDK1 activity through phosphorylation and activation of WEE1, and inhibition of CDC25B and CDC25C. {ECO:0000269|PubMed:14976552, ECO:0000269|PubMed:15150265, ECO:0000269|PubMed:20026642, ECO:0000269|PubMed:21985311}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000392006+7153_37333857.0DomainSAP
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000593587+7153_37233757.0DomainSAP
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000595018+7153_37233757.0DomainSAP
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000602130+7153_37333805.0DomainSAP
TgeneBRSK1chr19:41787180chr19:55795889ENST00000309383019492_5400779.0Compositional biasNote=Pro-rich
TgeneBRSK1chr19:41787180chr19:55795889ENST00000585418010492_5400344.0Compositional biasNote=Pro-rich
TgeneBRSK1chr19:41787180chr19:55795889ENST00000590333121492_54042795.0Compositional biasNote=Pro-rich
TgeneBRSK1chr19:41787180chr19:55795889ENST00000309383019314_3560779.0DomainUBA
TgeneBRSK1chr19:41787180chr19:55795889ENST0000030938301934_2850779.0DomainProtein kinase
TgeneBRSK1chr19:41787180chr19:55795889ENST00000585418010314_3560344.0DomainUBA
TgeneBRSK1chr19:41787180chr19:55795889ENST0000058541801034_2850344.0DomainProtein kinase
TgeneBRSK1chr19:41787180chr19:55795889ENST00000590333121314_35642795.0DomainUBA
TgeneBRSK1chr19:41787180chr19:55795889ENST0000030938301940_480779.0Nucleotide bindingATP
TgeneBRSK1chr19:41787180chr19:55795889ENST0000058541801040_480344.0Nucleotide bindingATP
TgeneBRSK1chr19:41787180chr19:55795889ENST0000059033312140_4842795.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000378215+114613_6660753.0Compositional biasNote=Gly-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000378215+114670_6890753.0Compositional biasNote=Asn-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000378215+114692_8110753.0Compositional biasNote=Pro-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000378215+114757_8450753.0Compositional biasNote=Tyr-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000378215+114806_8320753.0Compositional biasNote=Gln-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000392006+715613_666333857.0Compositional biasNote=Gly-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000392006+715670_689333857.0Compositional biasNote=Asn-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000392006+715692_811333857.0Compositional biasNote=Pro-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000392006+715757_845333857.0Compositional biasNote=Tyr-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000392006+715806_832333857.0Compositional biasNote=Gln-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000593587+715613_666233757.0Compositional biasNote=Gly-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000593587+715670_689233757.0Compositional biasNote=Asn-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000593587+715692_811233757.0Compositional biasNote=Pro-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000593587+715757_845233757.0Compositional biasNote=Tyr-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000593587+715806_832233757.0Compositional biasNote=Gln-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000595018+715613_666233757.0Compositional biasNote=Gly-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000595018+715670_689233757.0Compositional biasNote=Asn-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000595018+715692_811233757.0Compositional biasNote=Pro-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000595018+715757_845233757.0Compositional biasNote=Tyr-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000595018+715806_832233757.0Compositional biasNote=Gln-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000602130+715613_666333805.0Compositional biasNote=Gly-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000602130+715670_689333805.0Compositional biasNote=Asn-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000602130+715692_811333805.0Compositional biasNote=Pro-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000602130+715757_845333805.0Compositional biasNote=Tyr-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000602130+715806_832333805.0Compositional biasNote=Gln-rich
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000378215+114191_3880753.0DomainB30.2/SPRY
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000378215+1143_370753.0DomainSAP
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000392006+715191_388333857.0DomainB30.2/SPRY
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000593587+715191_388233757.0DomainB30.2/SPRY
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000595018+715191_388233757.0DomainB30.2/SPRY
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000602130+715191_388333805.0DomainB30.2/SPRY
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000378215+114612_6580753.0RegionNote=Necessary for transcription repression
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000392006+715612_658333857.0RegionNote=Necessary for transcription repression
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000593587+715612_658233757.0RegionNote=Necessary for transcription repression
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000595018+715612_658233757.0RegionNote=Necessary for transcription repression
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000602130+715612_658333805.0RegionNote=Necessary for transcription repression
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000378215+114612_6140753.0RepeatNote=1-1
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000378215+114620_6220753.0RepeatNote=1-2
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000378215+114639_6410753.0RepeatNote=1-3
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000378215+114645_6470753.0RepeatNote=1-4
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000378215+114656_6580753.0RepeatNote=1-5
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000392006+715612_614333857.0RepeatNote=1-1
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000392006+715620_622333857.0RepeatNote=1-2
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000392006+715639_641333857.0RepeatNote=1-3
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000392006+715645_647333857.0RepeatNote=1-4
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000392006+715656_658333857.0RepeatNote=1-5
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000593587+715612_614233757.0RepeatNote=1-1
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000593587+715620_622233757.0RepeatNote=1-2
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000593587+715639_641233757.0RepeatNote=1-3
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000593587+715645_647233757.0RepeatNote=1-4
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000593587+715656_658233757.0RepeatNote=1-5
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000595018+715612_614233757.0RepeatNote=1-1
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000595018+715620_622233757.0RepeatNote=1-2
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000595018+715639_641233757.0RepeatNote=1-3
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000595018+715645_647233757.0RepeatNote=1-4
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000595018+715656_658233757.0RepeatNote=1-5
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000602130+715612_614333805.0RepeatNote=1-1
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000602130+715620_622333805.0RepeatNote=1-2
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000602130+715639_641333805.0RepeatNote=1-3
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000602130+715645_647333805.0RepeatNote=1-4
HgeneHNRNPUL1chr19:41787180chr19:55795889ENST00000602130+715656_658333805.0RepeatNote=1-5
TgeneBRSK1chr19:41787180chr19:55795889ENST0000059033312134_28542795.0DomainProtein kinase


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Fusion Gene Sequence for HNRNPUL1-BRSK1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>37305_37305_1_HNRNPUL1-BRSK1_HNRNPUL1_chr19_41787180_ENST00000263367_BRSK1_chr19_55795889_ENST00000590333_length(transcript)=3650nt_BP=926nt
GTTTTCCGTTTGGGTTGGGGAGGGTCTCGAAAATGGGGATCCTAGGGTACGGAGCTCCGTGGGCTTGGCGGTCGTGCTAGCCCAGCGTGT
GGGCTGGGGGGTGGGGAGCCGTGTTTCCAGGGTGGGGAAGGAATGTCCAGGTGTGCGGGGCTGCGAGAGTTCTGAGGAAGGAGGATCCTG
GAATATGCCGCTGGATGCGATCCTGGGCGTTCTCCTATTTGGATGCCATGGACAATATTACCAGGCAGAACCAATTCTACGATACCCAAG
TCATCAAACAAGAAAACGAGTCAGGCTACGAGAGGAGACCACTGGAAATGGAGCAGCAGCAGGCCTATCGTCCAGAAATGAAGACAGAGA
TGAAGCAAGGAGCACCCACCAGCTTCCTCCCGCCTGAAGCTTCTCAACTCAAGCCAGACAGGCAGCAATTCCAGAGTCGAAAGAGGCCTT
ATGAAGAAAACCGGGGACGGGGGTACTTTGAGCACCGAGAGGATAGGAGGGGCCGCTCTCCTCAGCCTCCTGCTGAAGAGGATGAAGATG
ACTTTGATGATACCCTTGTTGCTATTGACACCTATAACTGCGACCTCCACTTCAAGGTGGCCCGAGATCGGAGTAGTGGCTATCCGCTCA
CAATTGAGGGCTTTGCATACCTGTGGTCAGGAGCCCGTGCCAGCTATGGGGTCAGAAGGGGCCGTGTATGCTTCGAGATGAAGATCAATG
AGGAAATCTCCGTGAAGCACCTTCCGTCTACAGAGCCTGACCCCCACGTGGTCCGTATCGGCTGGTCCCTGGACTCCTGCAGCACCCAGC
TAGGCGAAGAGCCTTTCTCCTATGGCTATGGAGGCACTGGGAAGAAGTCCACCAATAGCCGGTTTGAAAACTACGGAGACAAGTTTGCAG
AGAACGATGTGATTGGCTGCTTTGCGCACGCCCAATATGTGGGCCCCTATCGGCTGGAGAAGACGCTGGGCAAAGGACAGACAGGGCTGG
TTAAACTCGGGGTCCACTGCATCACGGGTCAGAAGGTCGCCATCAAGATCGTGAACCGGGAGAAGCTGTCGGAGTCGGTGCTGATGAAGG
TGGAGCGGGAGATCGCCATCCTGAAGCTCATCGAACACCCACATGTCCTCAAGCTCCACGACGTCTACGAGAACAAGAAATATTTGTACC
TGGTTCTGGAGCACGTCTCGGGGGGTGAGCTATTCGACTACCTGGTAAAGAAGGGGAGACTGACGCCCAAGGAGGCCCGAAAGTTCTTCC
GCCAGATTGTGTCTGCGCTGGACTTCTGCCACAGCTACTCCATCTGCCACAGAGACCTAAAGCCCGAGAACCTGCTTTTGGATGAGAAAA
ACAACATCCGCATTGCAGACTTCGGCATGGCGTCCCTGCAGGTGGGGGACAGCCTCCTGGAGACCAGCTGCGGGTCCCCCCATTATGCGT
GTCCAGAGGTGATTAAGGGGGAAAAATATGATGGCCGCCGGGCAGACATGTGGAGCTGTGGAGTCATCCTCTTCGCCCTGCTCGTGGGGG
CTCTGCCCTTTGATGACGACAACCTCCGCCAGCTGCTGGAGAAGGTGAAACGGGGCGTCTTCCACATGCCCCACTTCATTCCTCCAGATT
GCCAGAGCCTCCTGAGGGGAATGATCGAAGTGGAGCCCGAAAAAAGGCTCAGTCTGGAGCAAATTCAGAAACATCCTTGGTACCTAGGCG
GGAAACACGAGCCAGACCCGTGCCTGGAGCCAGCCCCTGGCCGCCGGGTAGCCATGCGGAGCCTGCCATCCAACGGAGAGCTGGACCCCG
ACGTCCTAGAGAGCATGGCATCACTGGGCTGCTTCAGGGACCGCGAGAGGCTGCATCGCGAGCTGCGCAGTGAGGAGGAGAACCAAGAAA
AGATGATATATTATCTGCTTTTGGATCGGAAGGAGCGGTATCCCAGCTGTGAGGACCAGGACCTGCCTCCCCGGAATGATGTTGACCCCC
CCCGGAAGCGTGTGGATTCTCCCATGCTGAGCCGTCACGGGAAGCGGCGACCAGAGCGGAAGTCCATGGAAGTCCTGAGCATCACCGATG
CCGGGGGTGGTGGCTCCCCTGTACCCACCCGACGGGCCTTGGAGATGGCCCAGCACAGCCAGAGATCCCGTAGCGTCAGTGGAGCCTCCA
CGGGTCTGTCCTCCAGCCCTCTAAGCAGCCCAAGGAGTCCGGTCTTTTCCTTTTCACCGGAGCCGGGGGCTGGAGATGAGGCTCGAGGCG
GGGGCTCCCCGACTTCCAAAACGCAGACGCTGCCTTCTCGGGGCCCCAGGGGTGGGGGCGCCGGGGAGCAGCCCCCGCCCCCCAGTGCCC
GCTCCACACCCCTGCCCGGCCCCCCAGGCTCCCCGCGCTCCTCTGGCGGGACCCCCTTGCACTCGCCTCTGCACACGCCCCGGGCCAGTC
CCACCGGGACCCCGGGGACAACACCACCCCCCAGCCCCGGCGGTGGCGTCGGGGGAGCCGCCTGGAGGAGTCGTCTCAACTCCATCCGCA
ACAGCTTCCTGGGCTCCCCTCGCTTTCACCGGCGCAAGATGCAGGTCCCTACCGCTGAGGAGATGTCCAGCTTGACGCCAGAGTCCTCCC
CGGAGCTGGCAAAACGCTCCTGGTTCGGGAACTTCATCTCCTTGGACAAAGAAGAACAAATATTCCTCGTGCTAAAGGACAAACCTCTCA
GCAGCATCAAAGCAGACATCGTCCATGCCTTTCTGTCGATCCCCAGCCTGAGTCACAGTGTGCTGTCACAGACCAGCTTCAGGGCCGAGT
ACAAGGCCAGTGGCGGCCCCTCCGTCTTCCAAAAGCCCGTCCGCTTCCAGGTGGACATCAGCTCCTCTGAGGGTCCAGAGCCCTCCCCGC
GACGGGACGGCAGCGGAGGTGGTGGCATCTACTCCGTCACCTTCACTCTCATCTCGGGTCCCAGCCGTCGGTTCAAGCGAGTGGTGGAGA
CCATCCAGGCACAGCTCCTGAGCACTCATGACCAGCCCTCCGTGCAGGCCCTGGCAGACGAGAAGAACGGGGCCCAGACCCGGCCTGCTG
GTGCCCCACCCCGAAGCCTGCAGCCCCCACCCGGCCGCCCAGACCCAGAGCTGAGCAGCTCTCCCCGCCGAGGCCCCCCCAAGGACAAGA
AGCTCCTGGCCACCAACGGGACCCCTCTGCCCTGACCCCACGGGGCCGGGGAGGGAGGGGACCCCCCTCCACCCCCCTTCCGTGCCCCCC
AACTGTGAATCTGTAAATAAGGCCCAAGGAACATGTCGGGAGGGGGGTGGACACAAAAACCGGCCTTGCCCTGCAGGGATGGGGCTCCAC
AGGCCGTGCCCAACTGGGGGTGGTTCTAGGGGAACAGGGGGCGGGGGAGCTGTTTCTATTTTATTTATTGATTAATTTATTATTTTATTT
ATTGATCAATCTCTCTGCGGGGTGGGGTGGGGGAGGGACGGGAGCTGGTTGGGGTGGCTTAGCAGATCCGGACAGGGCCCTCTGTCCCTG
TGTCGTCCCCAACCCCCTCTTCCCGGGCCCCTCCTCCCCTGGTCCTCCCCCCACGACCTTCTGTACGGATTTGCTCTCCGGAAGGAATTC

>37305_37305_1_HNRNPUL1-BRSK1_HNRNPUL1_chr19_41787180_ENST00000263367_BRSK1_chr19_55795889_ENST00000590333_length(amino acids)=1007AA_BP=255
MRKEDPGICRWMRSWAFSYLDAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQF
QSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVC
FEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFAHAQYVGPYRLEKTLG
KGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK
EARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVIL
FALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGRRVAMRSLPS
NGELDPDVLESMASLGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPRNDVDPPRKRVDSPMLSRHGKRRPERKSME
VLSITDAGGGGSPVPTRRALEMAQHSQRSRSVSGASTGLSSSPLSSPRSPVFSFSPEPGAGDEARGGGSPTSKTQTLPSRGPRGGGAGEQ
PPPPSARSTPLPGPPGSPRSSGGTPLHSPLHTPRASPTGTPGTTPPPSPGGGVGGAAWRSRLNSIRNSFLGSPRFHRRKMQVPTAEEMSS
LTPESSPELAKRSWFGNFISLDKEEQIFLVLKDKPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASGGPSVFQKPVRFQVDISSSE
GPEPSPRRDGSGGGGIYSVTFTLISGPSRRFKRVVETIQAQLLSTHDQPSVQALADEKNGAQTRPAGAPPRSLQPPPGRPDPELSSSPRR

--------------------------------------------------------------
>37305_37305_2_HNRNPUL1-BRSK1_HNRNPUL1_chr19_41787180_ENST00000352456_BRSK1_chr19_55795889_ENST00000590333_length(transcript)=3515nt_BP=791nt
ATTGTGGGAAGCTGGGAGGAGAGAGAGAGAGAGGAAGTCGGACGTGGGCGAGGGGCGGGGTGTCTGGACTGGAACCTCTGGGCCCACATG
CCATGGACAATATTACCAGGCAGAACCAATTCTACGATACCCAAGTCATCAAACAAGAAAACGAGTCAGGCTACGAGAGGAGACCACTGG
AAATGGAGCAGCAGCAGGCCTATCGTCCAGAAATGAAGACAGAGATGAAGCAAGGAGCACCCACCAGCTTCCTCCCGCCTGAAGCTTCTC
AACTCAAGCCAGACAGGCAGCAATTCCAGAGTCGAAAGAGGCCTTATGAAGAAAACCGGGGACGGGGGTACTTTGAGCACCGAGAGGATA
GGAGGGGCCGCTCTCCTCAGCCTCCTGCTGAAGAGGATGAAGATGACTTTGATGATACCCTTGTTGCTATTGACACCTATAACTGCGACC
TCCACTTCAAGGTGGCCCGAGATCGGAGTAGTGGCTATCCGCTCACAATTGAGGGCTTTGCATACCTGTGGTCAGGAGCCCGTGCCAGCT
ATGGGGTCAGAAGGGGCCGTGTATGCTTCGAGATGAAGATCAATGAGGAAATCTCCGTGAAGCACCTTCCGTCTACAGAGCCTGACCCCC
ACGTGGTCCGTATCGGCTGGTCCCTGGACTCCTGCAGCACCCAGCTAGGCGAAGAGCCTTTCTCCTATGGCTATGGAGGCACTGGGAAGA
AGTCCACCAATAGCCGGTTTGAAAACTACGGAGACAAGTTTGCAGAGAACGATGTGATTGGCTGCTTTGCGCACGCCCAATATGTGGGCC
CCTATCGGCTGGAGAAGACGCTGGGCAAAGGACAGACAGGGCTGGTTAAACTCGGGGTCCACTGCATCACGGGTCAGAAGGTCGCCATCA
AGATCGTGAACCGGGAGAAGCTGTCGGAGTCGGTGCTGATGAAGGTGGAGCGGGAGATCGCCATCCTGAAGCTCATCGAACACCCACATG
TCCTCAAGCTCCACGACGTCTACGAGAACAAGAAATATTTGTACCTGGTTCTGGAGCACGTCTCGGGGGGTGAGCTATTCGACTACCTGG
TAAAGAAGGGGAGACTGACGCCCAAGGAGGCCCGAAAGTTCTTCCGCCAGATTGTGTCTGCGCTGGACTTCTGCCACAGCTACTCCATCT
GCCACAGAGACCTAAAGCCCGAGAACCTGCTTTTGGATGAGAAAAACAACATCCGCATTGCAGACTTCGGCATGGCGTCCCTGCAGGTGG
GGGACAGCCTCCTGGAGACCAGCTGCGGGTCCCCCCATTATGCGTGTCCAGAGGTGATTAAGGGGGAAAAATATGATGGCCGCCGGGCAG
ACATGTGGAGCTGTGGAGTCATCCTCTTCGCCCTGCTCGTGGGGGCTCTGCCCTTTGATGACGACAACCTCCGCCAGCTGCTGGAGAAGG
TGAAACGGGGCGTCTTCCACATGCCCCACTTCATTCCTCCAGATTGCCAGAGCCTCCTGAGGGGAATGATCGAAGTGGAGCCCGAAAAAA
GGCTCAGTCTGGAGCAAATTCAGAAACATCCTTGGTACCTAGGCGGGAAACACGAGCCAGACCCGTGCCTGGAGCCAGCCCCTGGCCGCC
GGGTAGCCATGCGGAGCCTGCCATCCAACGGAGAGCTGGACCCCGACGTCCTAGAGAGCATGGCATCACTGGGCTGCTTCAGGGACCGCG
AGAGGCTGCATCGCGAGCTGCGCAGTGAGGAGGAGAACCAAGAAAAGATGATATATTATCTGCTTTTGGATCGGAAGGAGCGGTATCCCA
GCTGTGAGGACCAGGACCTGCCTCCCCGGAATGATGTTGACCCCCCCCGGAAGCGTGTGGATTCTCCCATGCTGAGCCGTCACGGGAAGC
GGCGACCAGAGCGGAAGTCCATGGAAGTCCTGAGCATCACCGATGCCGGGGGTGGTGGCTCCCCTGTACCCACCCGACGGGCCTTGGAGA
TGGCCCAGCACAGCCAGAGATCCCGTAGCGTCAGTGGAGCCTCCACGGGTCTGTCCTCCAGCCCTCTAAGCAGCCCAAGGAGTCCGGTCT
TTTCCTTTTCACCGGAGCCGGGGGCTGGAGATGAGGCTCGAGGCGGGGGCTCCCCGACTTCCAAAACGCAGACGCTGCCTTCTCGGGGCC
CCAGGGGTGGGGGCGCCGGGGAGCAGCCCCCGCCCCCCAGTGCCCGCTCCACACCCCTGCCCGGCCCCCCAGGCTCCCCGCGCTCCTCTG
GCGGGACCCCCTTGCACTCGCCTCTGCACACGCCCCGGGCCAGTCCCACCGGGACCCCGGGGACAACACCACCCCCCAGCCCCGGCGGTG
GCGTCGGGGGAGCCGCCTGGAGGAGTCGTCTCAACTCCATCCGCAACAGCTTCCTGGGCTCCCCTCGCTTTCACCGGCGCAAGATGCAGG
TCCCTACCGCTGAGGAGATGTCCAGCTTGACGCCAGAGTCCTCCCCGGAGCTGGCAAAACGCTCCTGGTTCGGGAACTTCATCTCCTTGG
ACAAAGAAGAACAAATATTCCTCGTGCTAAAGGACAAACCTCTCAGCAGCATCAAAGCAGACATCGTCCATGCCTTTCTGTCGATCCCCA
GCCTGAGTCACAGTGTGCTGTCACAGACCAGCTTCAGGGCCGAGTACAAGGCCAGTGGCGGCCCCTCCGTCTTCCAAAAGCCCGTCCGCT
TCCAGGTGGACATCAGCTCCTCTGAGGGTCCAGAGCCCTCCCCGCGACGGGACGGCAGCGGAGGTGGTGGCATCTACTCCGTCACCTTCA
CTCTCATCTCGGGTCCCAGCCGTCGGTTCAAGCGAGTGGTGGAGACCATCCAGGCACAGCTCCTGAGCACTCATGACCAGCCCTCCGTGC
AGGCCCTGGCAGACGAGAAGAACGGGGCCCAGACCCGGCCTGCTGGTGCCCCACCCCGAAGCCTGCAGCCCCCACCCGGCCGCCCAGACC
CAGAGCTGAGCAGCTCTCCCCGCCGAGGCCCCCCCAAGGACAAGAAGCTCCTGGCCACCAACGGGACCCCTCTGCCCTGACCCCACGGGG
CCGGGGAGGGAGGGGACCCCCCTCCACCCCCCTTCCGTGCCCCCCAACTGTGAATCTGTAAATAAGGCCCAAGGAACATGTCGGGAGGGG
GGTGGACACAAAAACCGGCCTTGCCCTGCAGGGATGGGGCTCCACAGGCCGTGCCCAACTGGGGGTGGTTCTAGGGGAACAGGGGGCGGG
GGAGCTGTTTCTATTTTATTTATTGATTAATTTATTATTTTATTTATTGATCAATCTCTCTGCGGGGTGGGGTGGGGGAGGGACGGGAGC
TGGTTGGGGTGGCTTAGCAGATCCGGACAGGGCCCTCTGTCCCTGTGTCGTCCCCAACCCCCTCTTCCCGGGCCCCTCCTCCCCTGGTCC
TCCCCCCACGACCTTCTGTACGGATTTGCTCTCCGGAAGGAATTCTGGTTTCGCGTGATCCTGCCTGCGTCCGTGTCTCTGATTCCGCCG

>37305_37305_2_HNRNPUL1-BRSK1_HNRNPUL1_chr19_41787180_ENST00000352456_BRSK1_chr19_55795889_ENST00000590333_length(amino acids)=1012AA_BP=260
MGGERERGSRTWARGGVSGLEPLGPHAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKP
DRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVR
RGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFAHAQYVGPYRL
EKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKG
RLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWS
CGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGRRVAM
RSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPRNDVDPPRKRVDSPMLSRHGKRRPE
RKSMEVLSITDAGGGGSPVPTRRALEMAQHSQRSRSVSGASTGLSSSPLSSPRSPVFSFSPEPGAGDEARGGGSPTSKTQTLPSRGPRGG
GAGEQPPPPSARSTPLPGPPGSPRSSGGTPLHSPLHTPRASPTGTPGTTPPPSPGGGVGGAAWRSRLNSIRNSFLGSPRFHRRKMQVPTA
EEMSSLTPESSPELAKRSWFGNFISLDKEEQIFLVLKDKPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASGGPSVFQKPVRFQVD
ISSSEGPEPSPRRDGSGGGGIYSVTFTLISGPSRRFKRVVETIQAQLLSTHDQPSVQALADEKNGAQTRPAGAPPRSLQPPPGRPDPELS

--------------------------------------------------------------
>37305_37305_3_HNRNPUL1-BRSK1_HNRNPUL1_chr19_41787180_ENST00000392006_BRSK1_chr19_55795889_ENST00000590333_length(transcript)=3896nt_BP=1172nt
CGGACGAGGCACGAGTGAGGGGGGAGGCGGTGGCGGCGGCCATTTTGAGCCGCTGCCGCCATTGGAGTGGGCCCCCCCCCTTTCCCCCTT
CGCCTCCTGACAGGAAAGGTTTAAGGGGGACAGAGCCCTGGGAGGCCGGGCCGGGCTCGGGGGCCACCCCGGGGGCCCGGGCCATGGATG
TGCGCCGTCTGAAGGTGAACGAACTTCGCGAGGAGCTGCAGCGCCGCGGCCTGGACACTCGAGGCCTCAAGGCCGAGCTTGCTGAGCGGC
TGCAGGCGGCGTTGGAGGCCGAGGAGCCTGACGACGAGCGGGAGCTCGACGCCGACGACGAACCGGGGCGACCCGGGCACATCAACGAGG
AGGTCGAGACCGAGGGGGGCTCCGAGCTGGAGGGGACCGCGCAGCCACCGCCGCCCGGGCTGCAGCCGCACGCGGAGCCCGGCGGCTACT
CGGGGCCGGACGGACATTATGCCATGGACAATATTACCAGGCAGAACCAATTCTACGATACCCAAGTCATCAAACAAGAAAACGAGTCAG
GCTACGAGAGGAGACCACTGGAAATGGAGCAGCAGCAGGCCTATCGTCCAGAAATGAAGACAGAGATGAAGCAAGGAGCACCCACCAGCT
TCCTCCCGCCTGAAGCTTCTCAACTCAAGCCAGACAGGCAGCAATTCCAGAGTCGAAAGAGGCCTTATGAAGAAAACCGGGGACGGGGGT
ACTTTGAGCACCGAGAGGATAGGAGGGGCCGCTCTCCTCAGCCTCCTGCTGAAGAGGATGAAGATGACTTTGATGATACCCTTGTTGCTA
TTGACACCTATAACTGCGACCTCCACTTCAAGGTGGCCCGAGATCGGAGTAGTGGCTATCCGCTCACAATTGAGGGCTTTGCATACCTGT
GGTCAGGAGCCCGTGCCAGCTATGGGGTCAGAAGGGGCCGTGTATGCTTCGAGATGAAGATCAATGAGGAAATCTCCGTGAAGCACCTTC
CGTCTACAGAGCCTGACCCCCACGTGGTCCGTATCGGCTGGTCCCTGGACTCCTGCAGCACCCAGCTAGGCGAAGAGCCTTTCTCCTATG
GCTATGGAGGCACTGGGAAGAAGTCCACCAATAGCCGGTTTGAAAACTACGGAGACAAGTTTGCAGAGAACGATGTGATTGGCTGCTTTG
CGCACGCCCAATATGTGGGCCCCTATCGGCTGGAGAAGACGCTGGGCAAAGGACAGACAGGGCTGGTTAAACTCGGGGTCCACTGCATCA
CGGGTCAGAAGGTCGCCATCAAGATCGTGAACCGGGAGAAGCTGTCGGAGTCGGTGCTGATGAAGGTGGAGCGGGAGATCGCCATCCTGA
AGCTCATCGAACACCCACATGTCCTCAAGCTCCACGACGTCTACGAGAACAAGAAATATTTGTACCTGGTTCTGGAGCACGTCTCGGGGG
GTGAGCTATTCGACTACCTGGTAAAGAAGGGGAGACTGACGCCCAAGGAGGCCCGAAAGTTCTTCCGCCAGATTGTGTCTGCGCTGGACT
TCTGCCACAGCTACTCCATCTGCCACAGAGACCTAAAGCCCGAGAACCTGCTTTTGGATGAGAAAAACAACATCCGCATTGCAGACTTCG
GCATGGCGTCCCTGCAGGTGGGGGACAGCCTCCTGGAGACCAGCTGCGGGTCCCCCCATTATGCGTGTCCAGAGGTGATTAAGGGGGAAA
AATATGATGGCCGCCGGGCAGACATGTGGAGCTGTGGAGTCATCCTCTTCGCCCTGCTCGTGGGGGCTCTGCCCTTTGATGACGACAACC
TCCGCCAGCTGCTGGAGAAGGTGAAACGGGGCGTCTTCCACATGCCCCACTTCATTCCTCCAGATTGCCAGAGCCTCCTGAGGGGAATGA
TCGAAGTGGAGCCCGAAAAAAGGCTCAGTCTGGAGCAAATTCAGAAACATCCTTGGTACCTAGGCGGGAAACACGAGCCAGACCCGTGCC
TGGAGCCAGCCCCTGGCCGCCGGGTAGCCATGCGGAGCCTGCCATCCAACGGAGAGCTGGACCCCGACGTCCTAGAGAGCATGGCATCAC
TGGGCTGCTTCAGGGACCGCGAGAGGCTGCATCGCGAGCTGCGCAGTGAGGAGGAGAACCAAGAAAAGATGATATATTATCTGCTTTTGG
ATCGGAAGGAGCGGTATCCCAGCTGTGAGGACCAGGACCTGCCTCCCCGGAATGATGTTGACCCCCCCCGGAAGCGTGTGGATTCTCCCA
TGCTGAGCCGTCACGGGAAGCGGCGACCAGAGCGGAAGTCCATGGAAGTCCTGAGCATCACCGATGCCGGGGGTGGTGGCTCCCCTGTAC
CCACCCGACGGGCCTTGGAGATGGCCCAGCACAGCCAGAGATCCCGTAGCGTCAGTGGAGCCTCCACGGGTCTGTCCTCCAGCCCTCTAA
GCAGCCCAAGGAGTCCGGTCTTTTCCTTTTCACCGGAGCCGGGGGCTGGAGATGAGGCTCGAGGCGGGGGCTCCCCGACTTCCAAAACGC
AGACGCTGCCTTCTCGGGGCCCCAGGGGTGGGGGCGCCGGGGAGCAGCCCCCGCCCCCCAGTGCCCGCTCCACACCCCTGCCCGGCCCCC
CAGGCTCCCCGCGCTCCTCTGGCGGGACCCCCTTGCACTCGCCTCTGCACACGCCCCGGGCCAGTCCCACCGGGACCCCGGGGACAACAC
CACCCCCCAGCCCCGGCGGTGGCGTCGGGGGAGCCGCCTGGAGGAGTCGTCTCAACTCCATCCGCAACAGCTTCCTGGGCTCCCCTCGCT
TTCACCGGCGCAAGATGCAGGTCCCTACCGCTGAGGAGATGTCCAGCTTGACGCCAGAGTCCTCCCCGGAGCTGGCAAAACGCTCCTGGT
TCGGGAACTTCATCTCCTTGGACAAAGAAGAACAAATATTCCTCGTGCTAAAGGACAAACCTCTCAGCAGCATCAAAGCAGACATCGTCC
ATGCCTTTCTGTCGATCCCCAGCCTGAGTCACAGTGTGCTGTCACAGACCAGCTTCAGGGCCGAGTACAAGGCCAGTGGCGGCCCCTCCG
TCTTCCAAAAGCCCGTCCGCTTCCAGGTGGACATCAGCTCCTCTGAGGGTCCAGAGCCCTCCCCGCGACGGGACGGCAGCGGAGGTGGTG
GCATCTACTCCGTCACCTTCACTCTCATCTCGGGTCCCAGCCGTCGGTTCAAGCGAGTGGTGGAGACCATCCAGGCACAGCTCCTGAGCA
CTCATGACCAGCCCTCCGTGCAGGCCCTGGCAGACGAGAAGAACGGGGCCCAGACCCGGCCTGCTGGTGCCCCACCCCGAAGCCTGCAGC
CCCCACCCGGCCGCCCAGACCCAGAGCTGAGCAGCTCTCCCCGCCGAGGCCCCCCCAAGGACAAGAAGCTCCTGGCCACCAACGGGACCC
CTCTGCCCTGACCCCACGGGGCCGGGGAGGGAGGGGACCCCCCTCCACCCCCCTTCCGTGCCCCCCAACTGTGAATCTGTAAATAAGGCC
CAAGGAACATGTCGGGAGGGGGGTGGACACAAAAACCGGCCTTGCCCTGCAGGGATGGGGCTCCACAGGCCGTGCCCAACTGGGGGTGGT
TCTAGGGGAACAGGGGGCGGGGGAGCTGTTTCTATTTTATTTATTGATTAATTTATTATTTTATTTATTGATCAATCTCTCTGCGGGGTG
GGGTGGGGGAGGGACGGGAGCTGGTTGGGGTGGCTTAGCAGATCCGGACAGGGCCCTCTGTCCCTGTGTCGTCCCCAACCCCCTCTTCCC
GGGCCCCTCCTCCCCTGGTCCTCCCCCCACGACCTTCTGTACGGATTTGCTCTCCGGAAGGAATTCTGGTTTCGCGTGATCCTGCCTGCG

>37305_37305_3_HNRNPUL1-BRSK1_HNRNPUL1_chr19_41787180_ENST00000392006_BRSK1_chr19_55795889_ENST00000590333_length(amino acids)=1128AA_BP=376
MSRCRHWSGPPPFPPSPPDRKGLRGTEPWEAGPGSGATPGARAMDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERE
LDADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAY
RPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARD
RSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFE
NYGDKFAENDVIGCFAHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVY
ENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS
CGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQ
KHPWYLGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLP
PRNDVDPPRKRVDSPMLSRHGKRRPERKSMEVLSITDAGGGGSPVPTRRALEMAQHSQRSRSVSGASTGLSSSPLSSPRSPVFSFSPEPG
AGDEARGGGSPTSKTQTLPSRGPRGGGAGEQPPPPSARSTPLPGPPGSPRSSGGTPLHSPLHTPRASPTGTPGTTPPPSPGGGVGGAAWR
SRLNSIRNSFLGSPRFHRRKMQVPTAEEMSSLTPESSPELAKRSWFGNFISLDKEEQIFLVLKDKPLSSIKADIVHAFLSIPSLSHSVLS
QTSFRAEYKASGGPSVFQKPVRFQVDISSSEGPEPSPRRDGSGGGGIYSVTFTLISGPSRRFKRVVETIQAQLLSTHDQPSVQALADEKN

--------------------------------------------------------------
>37305_37305_4_HNRNPUL1-BRSK1_HNRNPUL1_chr19_41787180_ENST00000593587_BRSK1_chr19_55795889_ENST00000590333_length(transcript)=3517nt_BP=793nt
GGAAACTGCTTTCTGGAGCCGAAGAGAGTCGGAAGAACAAGAGGTTTTCCGTTTGGGTTGGGGAGGGTCTCGAAAATGGGGATCCTAGGA
TGCCATGGACAATATTACCAGGCAGAACCAATTCTACGATACCCAAGTCATCAAACAAGAAAACGAGTCAGGCTACGAGAGGAGACCACT
GGAAATGGAGCAGCAGCAGGCCTATCGTCCAGAAATGAAGACAGAGATGAAGCAAGGAGCACCCACCAGCTTCCTCCCGCCTGAAGCTTC
TCAACTCAAGCCAGACAGGCAGCAATTCCAGAGTCGAAAGAGGCCTTATGAAGAAAACCGGGGACGGGGGTACTTTGAGCACCGAGAGGA
TAGGAGGGGCCGCTCTCCTCAGCCTCCTGCTGAAGAGGATGAAGATGACTTTGATGATACCCTTGTTGCTATTGACACCTATAACTGCGA
CCTCCACTTCAAGGTGGCCCGAGATCGGAGTAGTGGCTATCCGCTCACAATTGAGGGCTTTGCATACCTGTGGTCAGGAGCCCGTGCCAG
CTATGGGGTCAGAAGGGGCCGTGTATGCTTCGAGATGAAGATCAATGAGGAAATCTCCGTGAAGCACCTTCCGTCTACAGAGCCTGACCC
CCACGTGGTCCGTATCGGCTGGTCCCTGGACTCCTGCAGCACCCAGCTAGGCGAAGAGCCTTTCTCCTATGGCTATGGAGGCACTGGGAA
GAAGTCCACCAATAGCCGGTTTGAAAACTACGGAGACAAGTTTGCAGAGAACGATGTGATTGGCTGCTTTGCGCACGCCCAATATGTGGG
CCCCTATCGGCTGGAGAAGACGCTGGGCAAAGGACAGACAGGGCTGGTTAAACTCGGGGTCCACTGCATCACGGGTCAGAAGGTCGCCAT
CAAGATCGTGAACCGGGAGAAGCTGTCGGAGTCGGTGCTGATGAAGGTGGAGCGGGAGATCGCCATCCTGAAGCTCATCGAACACCCACA
TGTCCTCAAGCTCCACGACGTCTACGAGAACAAGAAATATTTGTACCTGGTTCTGGAGCACGTCTCGGGGGGTGAGCTATTCGACTACCT
GGTAAAGAAGGGGAGACTGACGCCCAAGGAGGCCCGAAAGTTCTTCCGCCAGATTGTGTCTGCGCTGGACTTCTGCCACAGCTACTCCAT
CTGCCACAGAGACCTAAAGCCCGAGAACCTGCTTTTGGATGAGAAAAACAACATCCGCATTGCAGACTTCGGCATGGCGTCCCTGCAGGT
GGGGGACAGCCTCCTGGAGACCAGCTGCGGGTCCCCCCATTATGCGTGTCCAGAGGTGATTAAGGGGGAAAAATATGATGGCCGCCGGGC
AGACATGTGGAGCTGTGGAGTCATCCTCTTCGCCCTGCTCGTGGGGGCTCTGCCCTTTGATGACGACAACCTCCGCCAGCTGCTGGAGAA
GGTGAAACGGGGCGTCTTCCACATGCCCCACTTCATTCCTCCAGATTGCCAGAGCCTCCTGAGGGGAATGATCGAAGTGGAGCCCGAAAA
AAGGCTCAGTCTGGAGCAAATTCAGAAACATCCTTGGTACCTAGGCGGGAAACACGAGCCAGACCCGTGCCTGGAGCCAGCCCCTGGCCG
CCGGGTAGCCATGCGGAGCCTGCCATCCAACGGAGAGCTGGACCCCGACGTCCTAGAGAGCATGGCATCACTGGGCTGCTTCAGGGACCG
CGAGAGGCTGCATCGCGAGCTGCGCAGTGAGGAGGAGAACCAAGAAAAGATGATATATTATCTGCTTTTGGATCGGAAGGAGCGGTATCC
CAGCTGTGAGGACCAGGACCTGCCTCCCCGGAATGATGTTGACCCCCCCCGGAAGCGTGTGGATTCTCCCATGCTGAGCCGTCACGGGAA
GCGGCGACCAGAGCGGAAGTCCATGGAAGTCCTGAGCATCACCGATGCCGGGGGTGGTGGCTCCCCTGTACCCACCCGACGGGCCTTGGA
GATGGCCCAGCACAGCCAGAGATCCCGTAGCGTCAGTGGAGCCTCCACGGGTCTGTCCTCCAGCCCTCTAAGCAGCCCAAGGAGTCCGGT
CTTTTCCTTTTCACCGGAGCCGGGGGCTGGAGATGAGGCTCGAGGCGGGGGCTCCCCGACTTCCAAAACGCAGACGCTGCCTTCTCGGGG
CCCCAGGGGTGGGGGCGCCGGGGAGCAGCCCCCGCCCCCCAGTGCCCGCTCCACACCCCTGCCCGGCCCCCCAGGCTCCCCGCGCTCCTC
TGGCGGGACCCCCTTGCACTCGCCTCTGCACACGCCCCGGGCCAGTCCCACCGGGACCCCGGGGACAACACCACCCCCCAGCCCCGGCGG
TGGCGTCGGGGGAGCCGCCTGGAGGAGTCGTCTCAACTCCATCCGCAACAGCTTCCTGGGCTCCCCTCGCTTTCACCGGCGCAAGATGCA
GGTCCCTACCGCTGAGGAGATGTCCAGCTTGACGCCAGAGTCCTCCCCGGAGCTGGCAAAACGCTCCTGGTTCGGGAACTTCATCTCCTT
GGACAAAGAAGAACAAATATTCCTCGTGCTAAAGGACAAACCTCTCAGCAGCATCAAAGCAGACATCGTCCATGCCTTTCTGTCGATCCC
CAGCCTGAGTCACAGTGTGCTGTCACAGACCAGCTTCAGGGCCGAGTACAAGGCCAGTGGCGGCCCCTCCGTCTTCCAAAAGCCCGTCCG
CTTCCAGGTGGACATCAGCTCCTCTGAGGGTCCAGAGCCCTCCCCGCGACGGGACGGCAGCGGAGGTGGTGGCATCTACTCCGTCACCTT
CACTCTCATCTCGGGTCCCAGCCGTCGGTTCAAGCGAGTGGTGGAGACCATCCAGGCACAGCTCCTGAGCACTCATGACCAGCCCTCCGT
GCAGGCCCTGGCAGACGAGAAGAACGGGGCCCAGACCCGGCCTGCTGGTGCCCCACCCCGAAGCCTGCAGCCCCCACCCGGCCGCCCAGA
CCCAGAGCTGAGCAGCTCTCCCCGCCGAGGCCCCCCCAAGGACAAGAAGCTCCTGGCCACCAACGGGACCCCTCTGCCCTGACCCCACGG
GGCCGGGGAGGGAGGGGACCCCCCTCCACCCCCCTTCCGTGCCCCCCAACTGTGAATCTGTAAATAAGGCCCAAGGAACATGTCGGGAGG
GGGGTGGACACAAAAACCGGCCTTGCCCTGCAGGGATGGGGCTCCACAGGCCGTGCCCAACTGGGGGTGGTTCTAGGGGAACAGGGGGCG
GGGGAGCTGTTTCTATTTTATTTATTGATTAATTTATTATTTTATTTATTGATCAATCTCTCTGCGGGGTGGGGTGGGGGAGGGACGGGA
GCTGGTTGGGGTGGCTTAGCAGATCCGGACAGGGCCCTCTGTCCCTGTGTCGTCCCCAACCCCCTCTTCCCGGGCCCCTCCTCCCCTGGT
CCTCCCCCCACGACCTTCTGTACGGATTTGCTCTCCGGAAGGAATTCTGGTTTCGCGTGATCCTGCCTGCGTCCGTGTCTCTGATTCCGC

>37305_37305_4_HNRNPUL1-BRSK1_HNRNPUL1_chr19_41787180_ENST00000593587_BRSK1_chr19_55795889_ENST00000590333_length(amino acids)=985AA_BP=233
MDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDR
RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPH
VVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFAHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIK
IVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSIC
HRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKV
KRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFRDRE
RLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPRNDVDPPRKRVDSPMLSRHGKRRPERKSMEVLSITDAGGGGSPVPTRRALEM
AQHSQRSRSVSGASTGLSSSPLSSPRSPVFSFSPEPGAGDEARGGGSPTSKTQTLPSRGPRGGGAGEQPPPPSARSTPLPGPPGSPRSSG
GTPLHSPLHTPRASPTGTPGTTPPPSPGGGVGGAAWRSRLNSIRNSFLGSPRFHRRKMQVPTAEEMSSLTPESSPELAKRSWFGNFISLD
KEEQIFLVLKDKPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASGGPSVFQKPVRFQVDISSSEGPEPSPRRDGSGGGGIYSVTFT

--------------------------------------------------------------
>37305_37305_5_HNRNPUL1-BRSK1_HNRNPUL1_chr19_41787180_ENST00000595018_BRSK1_chr19_55795889_ENST00000590333_length(transcript)=3492nt_BP=768nt
AGAGAGAGAGGAAGTCGGACGTGGGCGAGGGGCGGGGTGTCTGGACTGGAACCTCTGGGCCCACATGCCATGGACAATATTACCAGGCAG
AACCAATTCTACGATACCCAAGTCATCAAACAAGAAAACGAGTCAGGCTACGAGAGGAGACCACTGGAAATGGAGCAGCAGCAGGCCTAT
CGTCCAGAAATGAAGACAGAGATGAAGCAAGGAGCACCCACCAGCTTCCTCCCGCCTGAAGCTTCTCAACTCAAGCCAGACAGGCAGCAA
TTCCAGAGTCGAAAGAGGCCTTATGAAGAAAACCGGGGACGGGGGTACTTTGAGCACCGAGAGGATAGGAGGGGCCGCTCTCCTCAGCCT
CCTGCTGAAGAGGATGAAGATGACTTTGATGATACCCTTGTTGCTATTGACACCTATAACTGCGACCTCCACTTCAAGGTGGCCCGAGAT
CGGAGTAGTGGCTATCCGCTCACAATTGAGGGCTTTGCATACCTGTGGTCAGGAGCCCGTGCCAGCTATGGGGTCAGAAGGGGCCGTGTA
TGCTTCGAGATGAAGATCAATGAGGAAATCTCCGTGAAGCACCTTCCGTCTACAGAGCCTGACCCCCACGTGGTCCGTATCGGCTGGTCC
CTGGACTCCTGCAGCACCCAGCTAGGCGAAGAGCCTTTCTCCTATGGCTATGGAGGCACTGGGAAGAAGTCCACCAATAGCCGGTTTGAA
AACTACGGAGACAAGTTTGCAGAGAACGATGTGATTGGCTGCTTTGCGCACGCCCAATATGTGGGCCCCTATCGGCTGGAGAAGACGCTG
GGCAAAGGACAGACAGGGCTGGTTAAACTCGGGGTCCACTGCATCACGGGTCAGAAGGTCGCCATCAAGATCGTGAACCGGGAGAAGCTG
TCGGAGTCGGTGCTGATGAAGGTGGAGCGGGAGATCGCCATCCTGAAGCTCATCGAACACCCACATGTCCTCAAGCTCCACGACGTCTAC
GAGAACAAGAAATATTTGTACCTGGTTCTGGAGCACGTCTCGGGGGGTGAGCTATTCGACTACCTGGTAAAGAAGGGGAGACTGACGCCC
AAGGAGGCCCGAAAGTTCTTCCGCCAGATTGTGTCTGCGCTGGACTTCTGCCACAGCTACTCCATCTGCCACAGAGACCTAAAGCCCGAG
AACCTGCTTTTGGATGAGAAAAACAACATCCGCATTGCAGACTTCGGCATGGCGTCCCTGCAGGTGGGGGACAGCCTCCTGGAGACCAGC
TGCGGGTCCCCCCATTATGCGTGTCCAGAGGTGATTAAGGGGGAAAAATATGATGGCCGCCGGGCAGACATGTGGAGCTGTGGAGTCATC
CTCTTCGCCCTGCTCGTGGGGGCTCTGCCCTTTGATGACGACAACCTCCGCCAGCTGCTGGAGAAGGTGAAACGGGGCGTCTTCCACATG
CCCCACTTCATTCCTCCAGATTGCCAGAGCCTCCTGAGGGGAATGATCGAAGTGGAGCCCGAAAAAAGGCTCAGTCTGGAGCAAATTCAG
AAACATCCTTGGTACCTAGGCGGGAAACACGAGCCAGACCCGTGCCTGGAGCCAGCCCCTGGCCGCCGGGTAGCCATGCGGAGCCTGCCA
TCCAACGGAGAGCTGGACCCCGACGTCCTAGAGAGCATGGCATCACTGGGCTGCTTCAGGGACCGCGAGAGGCTGCATCGCGAGCTGCGC
AGTGAGGAGGAGAACCAAGAAAAGATGATATATTATCTGCTTTTGGATCGGAAGGAGCGGTATCCCAGCTGTGAGGACCAGGACCTGCCT
CCCCGGAATGATGTTGACCCCCCCCGGAAGCGTGTGGATTCTCCCATGCTGAGCCGTCACGGGAAGCGGCGACCAGAGCGGAAGTCCATG
GAAGTCCTGAGCATCACCGATGCCGGGGGTGGTGGCTCCCCTGTACCCACCCGACGGGCCTTGGAGATGGCCCAGCACAGCCAGAGATCC
CGTAGCGTCAGTGGAGCCTCCACGGGTCTGTCCTCCAGCCCTCTAAGCAGCCCAAGGAGTCCGGTCTTTTCCTTTTCACCGGAGCCGGGG
GCTGGAGATGAGGCTCGAGGCGGGGGCTCCCCGACTTCCAAAACGCAGACGCTGCCTTCTCGGGGCCCCAGGGGTGGGGGCGCCGGGGAG
CAGCCCCCGCCCCCCAGTGCCCGCTCCACACCCCTGCCCGGCCCCCCAGGCTCCCCGCGCTCCTCTGGCGGGACCCCCTTGCACTCGCCT
CTGCACACGCCCCGGGCCAGTCCCACCGGGACCCCGGGGACAACACCACCCCCCAGCCCCGGCGGTGGCGTCGGGGGAGCCGCCTGGAGG
AGTCGTCTCAACTCCATCCGCAACAGCTTCCTGGGCTCCCCTCGCTTTCACCGGCGCAAGATGCAGGTCCCTACCGCTGAGGAGATGTCC
AGCTTGACGCCAGAGTCCTCCCCGGAGCTGGCAAAACGCTCCTGGTTCGGGAACTTCATCTCCTTGGACAAAGAAGAACAAATATTCCTC
GTGCTAAAGGACAAACCTCTCAGCAGCATCAAAGCAGACATCGTCCATGCCTTTCTGTCGATCCCCAGCCTGAGTCACAGTGTGCTGTCA
CAGACCAGCTTCAGGGCCGAGTACAAGGCCAGTGGCGGCCCCTCCGTCTTCCAAAAGCCCGTCCGCTTCCAGGTGGACATCAGCTCCTCT
GAGGGTCCAGAGCCCTCCCCGCGACGGGACGGCAGCGGAGGTGGTGGCATCTACTCCGTCACCTTCACTCTCATCTCGGGTCCCAGCCGT
CGGTTCAAGCGAGTGGTGGAGACCATCCAGGCACAGCTCCTGAGCACTCATGACCAGCCCTCCGTGCAGGCCCTGGCAGACGAGAAGAAC
GGGGCCCAGACCCGGCCTGCTGGTGCCCCACCCCGAAGCCTGCAGCCCCCACCCGGCCGCCCAGACCCAGAGCTGAGCAGCTCTCCCCGC
CGAGGCCCCCCCAAGGACAAGAAGCTCCTGGCCACCAACGGGACCCCTCTGCCCTGACCCCACGGGGCCGGGGAGGGAGGGGACCCCCCT
CCACCCCCCTTCCGTGCCCCCCAACTGTGAATCTGTAAATAAGGCCCAAGGAACATGTCGGGAGGGGGGTGGACACAAAAACCGGCCTTG
CCCTGCAGGGATGGGGCTCCACAGGCCGTGCCCAACTGGGGGTGGTTCTAGGGGAACAGGGGGCGGGGGAGCTGTTTCTATTTTATTTAT
TGATTAATTTATTATTTTATTTATTGATCAATCTCTCTGCGGGGTGGGGTGGGGGAGGGACGGGAGCTGGTTGGGGTGGCTTAGCAGATC
CGGACAGGGCCCTCTGTCCCTGTGTCGTCCCCAACCCCCTCTTCCCGGGCCCCTCCTCCCCTGGTCCTCCCCCCACGACCTTCTGTACGG

>37305_37305_5_HNRNPUL1-BRSK1_HNRNPUL1_chr19_41787180_ENST00000595018_BRSK1_chr19_55795889_ENST00000590333_length(amino acids)=993AA_BP=241
MEPLGPHAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRG
YFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHL
PSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFAHAQYVGPYRLEKTLGKGQTGLVKLGVHCI
TGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALD
FCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDN
LRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMAS
LGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPRNDVDPPRKRVDSPMLSRHGKRRPERKSMEVLSITDAGGGGSPV
PTRRALEMAQHSQRSRSVSGASTGLSSSPLSSPRSPVFSFSPEPGAGDEARGGGSPTSKTQTLPSRGPRGGGAGEQPPPPSARSTPLPGP
PGSPRSSGGTPLHSPLHTPRASPTGTPGTTPPPSPGGGVGGAAWRSRLNSIRNSFLGSPRFHRRKMQVPTAEEMSSLTPESSPELAKRSW
FGNFISLDKEEQIFLVLKDKPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASGGPSVFQKPVRFQVDISSSEGPEPSPRRDGSGGG
GIYSVTFTLISGPSRRFKRVVETIQAQLLSTHDQPSVQALADEKNGAQTRPAGAPPRSLQPPPGRPDPELSSSPRRGPPKDKKLLATNGT

--------------------------------------------------------------
>37305_37305_6_HNRNPUL1-BRSK1_HNRNPUL1_chr19_41787180_ENST00000602130_BRSK1_chr19_55795889_ENST00000590333_length(transcript)=3776nt_BP=1052nt
CAGAGCCCTGGGAGGCCGGGCCGGGCTCGGGGGCCACCCCGGGGGCCCGGGCCATGGATGTGCGCCGTCTGAAGGTGAACGAACTTCGCG
AGGAGCTGCAGCGCCGCGGCCTGGACACTCGAGGCCTCAAGGCCGAGCTTGCTGAGCGGCTGCAGGCGGCGTTGGAGGCCGAGGAGCCTG
ACGACGAGCGGGAGCTCGACGCCGACGACGAACCGGGGCGACCCGGGCACATCAACGAGGAGGTCGAGACCGAGGGGGGCTCCGAGCTGG
AGGGGACCGCGCAGCCACCGCCGCCCGGGCTGCAGCCGCACGCGGAGCCCGGCGGCTACTCGGGGCCGGACGGACATTATGCCATGGACA
ATATTACCAGGCAGAACCAATTCTACGATACCCAAGTCATCAAACAAGAAAACGAGTCAGGCTACGAGAGGAGACCACTGGAAATGGAGC
AGCAGCAGGCCTATCGTCCAGAAATGAAGACAGAGATGAAGCAAGGAGCACCCACCAGCTTCCTCCCGCCTGAAGCTTCTCAACTCAAGC
CAGACAGGCAGCAATTCCAGAGTCGAAAGAGGCCTTATGAAGAAAACCGGGGACGGGGGTACTTTGAGCACCGAGAGGATAGGAGGGGCC
GCTCTCCTCAGCCTCCTGCTGAAGAGGATGAAGATGACTTTGATGATACCCTTGTTGCTATTGACACCTATAACTGCGACCTCCACTTCA
AGGTGGCCCGAGATCGGAGTAGTGGCTATCCGCTCACAATTGAGGGCTTTGCATACCTGTGGTCAGGAGCCCGTGCCAGCTATGGGGTCA
GAAGGGGCCGTGTATGCTTCGAGATGAAGATCAATGAGGAAATCTCCGTGAAGCACCTTCCGTCTACAGAGCCTGACCCCCACGTGGTCC
GTATCGGCTGGTCCCTGGACTCCTGCAGCACCCAGCTAGGCGAAGAGCCTTTCTCCTATGGCTATGGAGGCACTGGGAAGAAGTCCACCA
ATAGCCGGTTTGAAAACTACGGAGACAAGTTTGCAGAGAACGATGTGATTGGCTGCTTTGCGCACGCCCAATATGTGGGCCCCTATCGGC
TGGAGAAGACGCTGGGCAAAGGACAGACAGGGCTGGTTAAACTCGGGGTCCACTGCATCACGGGTCAGAAGGTCGCCATCAAGATCGTGA
ACCGGGAGAAGCTGTCGGAGTCGGTGCTGATGAAGGTGGAGCGGGAGATCGCCATCCTGAAGCTCATCGAACACCCACATGTCCTCAAGC
TCCACGACGTCTACGAGAACAAGAAATATTTGTACCTGGTTCTGGAGCACGTCTCGGGGGGTGAGCTATTCGACTACCTGGTAAAGAAGG
GGAGACTGACGCCCAAGGAGGCCCGAAAGTTCTTCCGCCAGATTGTGTCTGCGCTGGACTTCTGCCACAGCTACTCCATCTGCCACAGAG
ACCTAAAGCCCGAGAACCTGCTTTTGGATGAGAAAAACAACATCCGCATTGCAGACTTCGGCATGGCGTCCCTGCAGGTGGGGGACAGCC
TCCTGGAGACCAGCTGCGGGTCCCCCCATTATGCGTGTCCAGAGGTGATTAAGGGGGAAAAATATGATGGCCGCCGGGCAGACATGTGGA
GCTGTGGAGTCATCCTCTTCGCCCTGCTCGTGGGGGCTCTGCCCTTTGATGACGACAACCTCCGCCAGCTGCTGGAGAAGGTGAAACGGG
GCGTCTTCCACATGCCCCACTTCATTCCTCCAGATTGCCAGAGCCTCCTGAGGGGAATGATCGAAGTGGAGCCCGAAAAAAGGCTCAGTC
TGGAGCAAATTCAGAAACATCCTTGGTACCTAGGCGGGAAACACGAGCCAGACCCGTGCCTGGAGCCAGCCCCTGGCCGCCGGGTAGCCA
TGCGGAGCCTGCCATCCAACGGAGAGCTGGACCCCGACGTCCTAGAGAGCATGGCATCACTGGGCTGCTTCAGGGACCGCGAGAGGCTGC
ATCGCGAGCTGCGCAGTGAGGAGGAGAACCAAGAAAAGATGATATATTATCTGCTTTTGGATCGGAAGGAGCGGTATCCCAGCTGTGAGG
ACCAGGACCTGCCTCCCCGGAATGATGTTGACCCCCCCCGGAAGCGTGTGGATTCTCCCATGCTGAGCCGTCACGGGAAGCGGCGACCAG
AGCGGAAGTCCATGGAAGTCCTGAGCATCACCGATGCCGGGGGTGGTGGCTCCCCTGTACCCACCCGACGGGCCTTGGAGATGGCCCAGC
ACAGCCAGAGATCCCGTAGCGTCAGTGGAGCCTCCACGGGTCTGTCCTCCAGCCCTCTAAGCAGCCCAAGGAGTCCGGTCTTTTCCTTTT
CACCGGAGCCGGGGGCTGGAGATGAGGCTCGAGGCGGGGGCTCCCCGACTTCCAAAACGCAGACGCTGCCTTCTCGGGGCCCCAGGGGTG
GGGGCGCCGGGGAGCAGCCCCCGCCCCCCAGTGCCCGCTCCACACCCCTGCCCGGCCCCCCAGGCTCCCCGCGCTCCTCTGGCGGGACCC
CCTTGCACTCGCCTCTGCACACGCCCCGGGCCAGTCCCACCGGGACCCCGGGGACAACACCACCCCCCAGCCCCGGCGGTGGCGTCGGGG
GAGCCGCCTGGAGGAGTCGTCTCAACTCCATCCGCAACAGCTTCCTGGGCTCCCCTCGCTTTCACCGGCGCAAGATGCAGGTCCCTACCG
CTGAGGAGATGTCCAGCTTGACGCCAGAGTCCTCCCCGGAGCTGGCAAAACGCTCCTGGTTCGGGAACTTCATCTCCTTGGACAAAGAAG
AACAAATATTCCTCGTGCTAAAGGACAAACCTCTCAGCAGCATCAAAGCAGACATCGTCCATGCCTTTCTGTCGATCCCCAGCCTGAGTC
ACAGTGTGCTGTCACAGACCAGCTTCAGGGCCGAGTACAAGGCCAGTGGCGGCCCCTCCGTCTTCCAAAAGCCCGTCCGCTTCCAGGTGG
ACATCAGCTCCTCTGAGGGTCCAGAGCCCTCCCCGCGACGGGACGGCAGCGGAGGTGGTGGCATCTACTCCGTCACCTTCACTCTCATCT
CGGGTCCCAGCCGTCGGTTCAAGCGAGTGGTGGAGACCATCCAGGCACAGCTCCTGAGCACTCATGACCAGCCCTCCGTGCAGGCCCTGG
CAGACGAGAAGAACGGGGCCCAGACCCGGCCTGCTGGTGCCCCACCCCGAAGCCTGCAGCCCCCACCCGGCCGCCCAGACCCAGAGCTGA
GCAGCTCTCCCCGCCGAGGCCCCCCCAAGGACAAGAAGCTCCTGGCCACCAACGGGACCCCTCTGCCCTGACCCCACGGGGCCGGGGAGG
GAGGGGACCCCCCTCCACCCCCCTTCCGTGCCCCCCAACTGTGAATCTGTAAATAAGGCCCAAGGAACATGTCGGGAGGGGGGTGGACAC
AAAAACCGGCCTTGCCCTGCAGGGATGGGGCTCCACAGGCCGTGCCCAACTGGGGGTGGTTCTAGGGGAACAGGGGGCGGGGGAGCTGTT
TCTATTTTATTTATTGATTAATTTATTATTTTATTTATTGATCAATCTCTCTGCGGGGTGGGGTGGGGGAGGGACGGGAGCTGGTTGGGG
TGGCTTAGCAGATCCGGACAGGGCCCTCTGTCCCTGTGTCGTCCCCAACCCCCTCTTCCCGGGCCCCTCCTCCCCTGGTCCTCCCCCCAC

>37305_37305_6_HNRNPUL1-BRSK1_HNRNPUL1_chr19_41787180_ENST00000602130_BRSK1_chr19_55795889_ENST00000590333_length(amino acids)=1085AA_BP=333
MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELDADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPHAEPG
GYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRG
RGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVK
HLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFAHAQYVGPYRLEKTLGKGQTGLVKLGVH
CITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSA
LDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDD
DNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESM
ASLGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPRNDVDPPRKRVDSPMLSRHGKRRPERKSMEVLSITDAGGGGS
PVPTRRALEMAQHSQRSRSVSGASTGLSSSPLSSPRSPVFSFSPEPGAGDEARGGGSPTSKTQTLPSRGPRGGGAGEQPPPPSARSTPLP
GPPGSPRSSGGTPLHSPLHTPRASPTGTPGTTPPPSPGGGVGGAAWRSRLNSIRNSFLGSPRFHRRKMQVPTAEEMSSLTPESSPELAKR
SWFGNFISLDKEEQIFLVLKDKPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASGGPSVFQKPVRFQVDISSSEGPEPSPRRDGSG
GGGIYSVTFTLISGPSRRFKRVVETIQAQLLSTHDQPSVQALADEKNGAQTRPAGAPPRSLQPPPGRPDPELSSSPRRGPPKDKKLLATN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for HNRNPUL1-BRSK1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for HNRNPUL1-BRSK1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for HNRNPUL1-BRSK1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource