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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ALB-TF (FusionGDB2 ID:3798)

Fusion Gene Summary for ALB-TF

check button Fusion gene summary
Fusion gene informationFusion gene name: ALB-TF
Fusion gene ID: 3798
HgeneTgene
Gene symbol

ALB

TF

Gene ID

213

7018

Gene namealbumintransferrin
SynonymsHSA|PRO0883|PRO0903|PRO1341HEL-S-71p|PRO1557|PRO2086|TFQTL1
Cytomap

4q13.3

3q22.1

Type of geneprotein-codingprotein-coding
Descriptionserum albuminserotransferrinbeta-1 metal-binding globulinepididymis secretory sperm binding protein Li 71psiderophilin
Modification date2020032920200313
UniProtAcc

P02768

GTF2A1L

Ensembl transtripts involved in fusion geneENST00000505649, ENST00000295897, 
ENST00000401494, ENST00000415165, 
ENST00000503124, ENST00000509063, 
ENST00000264998, ENST00000402696, 
ENST00000475382, 
Fusion gene scores* DoF score66 X 51 X 5=168309 X 12 X 4=432
# samples 7413
** MAII scorelog2(74/16830*10)=-4.507366095701
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/432*10)=-1.73251968913501
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ALB [Title/Abstract] AND TF [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTF(133495892)-ALB(74280797), # samples:2
TF(133490670)-ALB(74279289), # samples:2
ALB(74283351)-TF(133497492), # samples:1
ALB(74272402)-TF(133495984), # samples:1
ALB(74285355)-TF(133475820), # samples:1
ALB(74283820)-TF(133497528), # samples:1
Anticipated loss of major functional domain due to fusion event.ALB-TF seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ALB-TF seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ALB-TF seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
TF-ALB seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
TF-ALB seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
TF-ALB seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneALB

GO:0009267

cellular response to starvation

16245148

HgeneALB

GO:0043066

negative regulation of apoptotic process

16153637

HgeneALB

GO:0051659

maintenance of mitochondrion location

16153637

TgeneTF

GO:0048260

positive regulation of receptor-mediated endocytosis

12704209


check buttonFusion gene breakpoints across ALB (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TF (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CHOLTCGA-W5-AA2X-11AALBchr4

74272402

+TFchr3

133495984

+
ChimerDB4CHOLTCGA-W5-AA31-11AALBchr4

74285355

+TFchr3

133475820

+
ChimerDB4CHOLTCGA-W5-AA34-11AALBchr4

74283351

+TFchr3

133497492

+
ChiTaRS5.0N/AAI065112ALBchr4

74283820

-TFchr3

133497528

+


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Fusion Gene ORF analysis for ALB-TF

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000505649ENST00000264998ALBchr4

74285355

+TFchr3

133475820

+
3UTR-3CDSENST00000505649ENST00000402696ALBchr4

74285355

+TFchr3

133475820

+
3UTR-3UTRENST00000505649ENST00000264998ALBchr4

74283820

-TFchr3

133497528

+
3UTR-3UTRENST00000505649ENST00000402696ALBchr4

74283820

-TFchr3

133497528

+
3UTR-intronENST00000505649ENST00000475382ALBchr4

74285355

+TFchr3

133475820

+
3UTR-intronENST00000505649ENST00000475382ALBchr4

74283820

-TFchr3

133497528

+
5CDS-3UTRENST00000295897ENST00000264998ALBchr4

74283351

+TFchr3

133497492

+
5CDS-3UTRENST00000295897ENST00000264998ALBchr4

74283820

-TFchr3

133497528

+
5CDS-3UTRENST00000295897ENST00000402696ALBchr4

74283351

+TFchr3

133497492

+
5CDS-3UTRENST00000295897ENST00000402696ALBchr4

74283820

-TFchr3

133497528

+
5CDS-3UTRENST00000401494ENST00000264998ALBchr4

74283351

+TFchr3

133497492

+
5CDS-3UTRENST00000401494ENST00000264998ALBchr4

74283820

-TFchr3

133497528

+
5CDS-3UTRENST00000401494ENST00000402696ALBchr4

74283351

+TFchr3

133497492

+
5CDS-3UTRENST00000401494ENST00000402696ALBchr4

74283820

-TFchr3

133497528

+
5CDS-3UTRENST00000415165ENST00000264998ALBchr4

74283351

+TFchr3

133497492

+
5CDS-3UTRENST00000415165ENST00000264998ALBchr4

74283820

-TFchr3

133497528

+
5CDS-3UTRENST00000415165ENST00000402696ALBchr4

74283351

+TFchr3

133497492

+
5CDS-3UTRENST00000415165ENST00000402696ALBchr4

74283820

-TFchr3

133497528

+
5CDS-3UTRENST00000503124ENST00000264998ALBchr4

74283351

+TFchr3

133497492

+
5CDS-3UTRENST00000503124ENST00000264998ALBchr4

74283820

-TFchr3

133497528

+
5CDS-3UTRENST00000503124ENST00000402696ALBchr4

74283351

+TFchr3

133497492

+
5CDS-3UTRENST00000503124ENST00000402696ALBchr4

74283820

-TFchr3

133497528

+
5CDS-3UTRENST00000509063ENST00000264998ALBchr4

74283351

+TFchr3

133497492

+
5CDS-3UTRENST00000509063ENST00000264998ALBchr4

74283820

-TFchr3

133497528

+
5CDS-3UTRENST00000509063ENST00000402696ALBchr4

74283351

+TFchr3

133497492

+
5CDS-3UTRENST00000509063ENST00000402696ALBchr4

74283820

-TFchr3

133497528

+
5CDS-intronENST00000295897ENST00000475382ALBchr4

74272402

+TFchr3

133495984

+
5CDS-intronENST00000295897ENST00000475382ALBchr4

74285355

+TFchr3

133475820

+
5CDS-intronENST00000295897ENST00000475382ALBchr4

74283351

+TFchr3

133497492

+
5CDS-intronENST00000295897ENST00000475382ALBchr4

74283820

-TFchr3

133497528

+
5CDS-intronENST00000401494ENST00000475382ALBchr4

74285355

+TFchr3

133475820

+
5CDS-intronENST00000401494ENST00000475382ALBchr4

74283351

+TFchr3

133497492

+
5CDS-intronENST00000401494ENST00000475382ALBchr4

74283820

-TFchr3

133497528

+
5CDS-intronENST00000415165ENST00000475382ALBchr4

74285355

+TFchr3

133475820

+
5CDS-intronENST00000415165ENST00000475382ALBchr4

74283351

+TFchr3

133497492

+
5CDS-intronENST00000415165ENST00000475382ALBchr4

74283820

-TFchr3

133497528

+
5CDS-intronENST00000503124ENST00000475382ALBchr4

74285355

+TFchr3

133475820

+
5CDS-intronENST00000503124ENST00000475382ALBchr4

74283351

+TFchr3

133497492

+
5CDS-intronENST00000503124ENST00000475382ALBchr4

74283820

-TFchr3

133497528

+
5CDS-intronENST00000509063ENST00000475382ALBchr4

74272402

+TFchr3

133495984

+
5CDS-intronENST00000509063ENST00000475382ALBchr4

74285355

+TFchr3

133475820

+
5CDS-intronENST00000509063ENST00000475382ALBchr4

74283351

+TFchr3

133497492

+
5CDS-intronENST00000509063ENST00000475382ALBchr4

74283820

-TFchr3

133497528

+
5UTR-3CDSENST00000503124ENST00000264998ALBchr4

74272402

+TFchr3

133495984

+
5UTR-3CDSENST00000503124ENST00000402696ALBchr4

74272402

+TFchr3

133495984

+
5UTR-intronENST00000503124ENST00000475382ALBchr4

74272402

+TFchr3

133495984

+
Frame-shiftENST00000295897ENST00000264998ALBchr4

74285355

+TFchr3

133475820

+
Frame-shiftENST00000295897ENST00000402696ALBchr4

74285355

+TFchr3

133475820

+
Frame-shiftENST00000401494ENST00000264998ALBchr4

74285355

+TFchr3

133475820

+
Frame-shiftENST00000401494ENST00000402696ALBchr4

74285355

+TFchr3

133475820

+
Frame-shiftENST00000415165ENST00000264998ALBchr4

74285355

+TFchr3

133475820

+
Frame-shiftENST00000415165ENST00000402696ALBchr4

74285355

+TFchr3

133475820

+
Frame-shiftENST00000503124ENST00000264998ALBchr4

74285355

+TFchr3

133475820

+
Frame-shiftENST00000503124ENST00000402696ALBchr4

74285355

+TFchr3

133475820

+
Frame-shiftENST00000509063ENST00000264998ALBchr4

74285355

+TFchr3

133475820

+
Frame-shiftENST00000509063ENST00000402696ALBchr4

74285355

+TFchr3

133475820

+
In-frameENST00000295897ENST00000264998ALBchr4

74272402

+TFchr3

133495984

+
In-frameENST00000295897ENST00000402696ALBchr4

74272402

+TFchr3

133495984

+
In-frameENST00000509063ENST00000264998ALBchr4

74272402

+TFchr3

133495984

+
In-frameENST00000509063ENST00000402696ALBchr4

74272402

+TFchr3

133495984

+
intron-3CDSENST00000401494ENST00000264998ALBchr4

74272402

+TFchr3

133495984

+
intron-3CDSENST00000401494ENST00000402696ALBchr4

74272402

+TFchr3

133495984

+
intron-3CDSENST00000415165ENST00000264998ALBchr4

74272402

+TFchr3

133495984

+
intron-3CDSENST00000415165ENST00000402696ALBchr4

74272402

+TFchr3

133495984

+
intron-3CDSENST00000505649ENST00000264998ALBchr4

74272402

+TFchr3

133495984

+
intron-3CDSENST00000505649ENST00000402696ALBchr4

74272402

+TFchr3

133495984

+
intron-3UTRENST00000505649ENST00000264998ALBchr4

74283351

+TFchr3

133497492

+
intron-3UTRENST00000505649ENST00000402696ALBchr4

74283351

+TFchr3

133497492

+
intron-intronENST00000401494ENST00000475382ALBchr4

74272402

+TFchr3

133495984

+
intron-intronENST00000415165ENST00000475382ALBchr4

74272402

+TFchr3

133495984

+
intron-intronENST00000505649ENST00000475382ALBchr4

74272402

+TFchr3

133495984

+
intron-intronENST00000505649ENST00000475382ALBchr4

74283351

+TFchr3

133497492

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000295897ALBchr474272402+ENST00000402696TFchr3133495984+82130253681191
ENST00000295897ALBchr474272402+ENST00000264998TFchr3133495984+6063026232286
ENST00000509063ALBchr474272402+ENST00000402696TFchr3133495984+75623747174691
ENST00000509063ALBchr474272402+ENST00000264998TFchr3133495984+5412372425777

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000295897ENST00000402696ALBchr474272402+TFchr3133495984+0.637459160.36254084
ENST00000295897ENST00000264998ALBchr474272402+TFchr3133495984+0.0593860970.94061387
ENST00000509063ENST00000402696ALBchr474272402+TFchr3133495984+0.49188340.5081166
ENST00000509063ENST00000264998ALBchr474272402+TFchr3133495984+0.0622350420.937765

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Fusion Genomic Features for ALB-TF


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ALB-TF


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:133495892/chr3:74280797)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ALB

P02768

TF

GTF2A1L

FUNCTION: Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (PubMed:19021548). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity). The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity). The rank order of affinity is zinc > calcium > magnesium (By similarity). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed:6234017). Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed:6234017). {ECO:0000250|UniProtKB:P02769, ECO:0000269|PubMed:19021548, ECO:0000269|PubMed:6234017, ECO:0000305|PubMed:1630489}.478

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTFchr4:74272402chr3:133495984ENST0000040269601725_3470699.0DomainTransferrin-like 1
TgeneTFchr4:74272402chr3:133495984ENST00000402696017361_6830699.0DomainTransferrin-like 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneALBchr4:74272402chr3:133495984ENST00000295897+11519_2100661.0DomainAlbumin 1
HgeneALBchr4:74272402chr3:133495984ENST00000295897+115211_4030661.0DomainAlbumin 2
HgeneALBchr4:74272402chr3:133495984ENST00000295897+115404_6010661.0DomainAlbumin 3
HgeneALBchr4:74272402chr3:133495984ENST00000509063+11419_2100605.0DomainAlbumin 1
HgeneALBchr4:74272402chr3:133495984ENST00000509063+114211_4030605.0DomainAlbumin 2
HgeneALBchr4:74272402chr3:133495984ENST00000509063+114404_6010605.0DomainAlbumin 3


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Fusion Gene Sequence for ALB-TF


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>3798_3798_1_ALB-TF_ALB_chr4_74272402_ENST00000295897_TF_chr3_133495984_ENST00000264998_length(transcript)=606nt_BP=302nt
AATTATTGGTTAAAGAAGTATATTAGTGCTAATTTCCCTCCGTTTGTCCTAGCTTTTCTCTTCTGTCAACCCCACACGCCTTTGGCACAA
TGAAGTGGGTAACCTTTATTTCCCTTCTTTTTCTCTTTAGCTCGGCTTATTCCAGGGGTGTGTTTCGTCGAGATGCACACAAGAGTGAGG
TTGCTCATCGGTTTAAAGATTTGGGAGAAGAAAATTTCAAAGCCTTATTAGTGAATGAAGTAACTGAATTTGCAAAAACATGTGTTGCTG
ATGAGTCAGCTGAAAATTGTGACAAATCACTTATGTTTGGCCAAACTTCATGACAGAAACACATATGAAAAATACTTAGGAGAAGAATAT
GTCAAGGCTGTTGGTAACCTGAGAAAATGCTCCACCTCATCACTCCTGGAAGCCTGCACTTTCCGTAGACCTTAAAATCTCAGAGGTAGG
GCTGCCACCAAGGTGAAGATGGGAACGCAGATGATCCATGAGTTTGCCCTGGTTTCACTGGCCCAAGTGGTTTGTGCTAACCACGTCTGT

>3798_3798_1_ALB-TF_ALB_chr4_74272402_ENST00000295897_TF_chr3_133495984_ENST00000264998_length(amino acids)=86AA_BP=

--------------------------------------------------------------
>3798_3798_2_ALB-TF_ALB_chr4_74272402_ENST00000295897_TF_chr3_133495984_ENST00000402696_length(transcript)=821nt_BP=302nt
AATTATTGGTTAAAGAAGTATATTAGTGCTAATTTCCCTCCGTTTGTCCTAGCTTTTCTCTTCTGTCAACCCCACACGCCTTTGGCACAA
TGAAGTGGGTAACCTTTATTTCCCTTCTTTTTCTCTTTAGCTCGGCTTATTCCAGGGGTGTGTTTCGTCGAGATGCACACAAGAGTGAGG
TTGCTCATCGGTTTAAAGATTTGGGAGAAGAAAATTTCAAAGCCTTATTAGTGAATGAAGTAACTGAATTTGCAAAAACATGTGTTGCTG
ATGAGTCAGCTGAAAATTGTGACAAATCACTTATGTTTGGCCAAACTTCATGACAGAAACACATATGAAAAATACTTAGGAGAAGAATAT
GTCAAGGCTGTTGGTAACCTGAGAAAATGCTCCACCTCATCACTCCTGGAAGCCTGCACTTTCCGTAGACCTTAAAATCTCAGAGGTAGG
GCTGCCACCAAGGTGAAGATGGGAACGCAGATGATCCATGAGTTTGCCCTGGTTTCACTGGCCCAAGTGGTTTGTGCTAACCACGTCTGT
CTTCACAGCTCTGTGTTGCCATGTGTGCTGAACAAAAAATAAAAATTATTATTGATTTTATATTTCAAAAACTCCATTCTTTCCTAAATA
TTTTCAACAAAGGATTTCTTTATGCATTCTGCCTAAATACCTATGCAACTGAGCCCTTCCTTCTCAGCTCAAGATTCGTCTGGTCTTTCC
CTACAGCTTTGTGTGTGCCATGGCCACATCTCCTGGGTACAGTTCAAGGAGACATCTTTTCTAAAAGGGTCTGCGTGATCATTAAAATAT

>3798_3798_2_ALB-TF_ALB_chr4_74272402_ENST00000295897_TF_chr3_133495984_ENST00000402696_length(amino acids)=91AA_BP=
MSSQLCVAMCAEQKIKIIIDFIFQKLHSFLNIFNKGFLYAFCLNTYATEPFLLSSRFVWSFPTALCVPWPHLLGTVQGDIFSKRVCVIIK

--------------------------------------------------------------
>3798_3798_3_ALB-TF_ALB_chr4_74272402_ENST00000509063_TF_chr3_133495984_ENST00000264998_length(transcript)=541nt_BP=237nt
TCAACCCCACACGCCTTTGGCACAATGAAGTGGGTAACCTTTATTTCCCTTCTTTTTCTCTTTAGCTCGGCTTATTCCAGGGGTGTGTTT
CGTCGAGATGCACACAAGAGTGAGGTTGCTCATCGGTTTAAAGATTTGGGAGAAGAAAATTTCAAAGCCTTATTAGTGAATGAAGTAACT
GAATTTGCAAAAACATGTGTTGCTGATGAGTCAGCTGAAAATTGTGACAAATCACTTATGTTTGGCCAAACTTCATGACAGAAACACATA
TGAAAAATACTTAGGAGAAGAATATGTCAAGGCTGTTGGTAACCTGAGAAAATGCTCCACCTCATCACTCCTGGAAGCCTGCACTTTCCG
TAGACCTTAAAATCTCAGAGGTAGGGCTGCCACCAAGGTGAAGATGGGAACGCAGATGATCCATGAGTTTGCCCTGGTTTCACTGGCCCA
AGTGGTTTGTGCTAACCACGTCTGTCTTCACAGCTCTGTGTTGCCATGTGTGCTGAACAAAAAATAAAAATTATTATTGATTTTATATTT

>3798_3798_3_ALB-TF_ALB_chr4_74272402_ENST00000509063_TF_chr3_133495984_ENST00000264998_length(amino acids)=77AA_BP=

--------------------------------------------------------------
>3798_3798_4_ALB-TF_ALB_chr4_74272402_ENST00000509063_TF_chr3_133495984_ENST00000402696_length(transcript)=756nt_BP=237nt
TCAACCCCACACGCCTTTGGCACAATGAAGTGGGTAACCTTTATTTCCCTTCTTTTTCTCTTTAGCTCGGCTTATTCCAGGGGTGTGTTT
CGTCGAGATGCACACAAGAGTGAGGTTGCTCATCGGTTTAAAGATTTGGGAGAAGAAAATTTCAAAGCCTTATTAGTGAATGAAGTAACT
GAATTTGCAAAAACATGTGTTGCTGATGAGTCAGCTGAAAATTGTGACAAATCACTTATGTTTGGCCAAACTTCATGACAGAAACACATA
TGAAAAATACTTAGGAGAAGAATATGTCAAGGCTGTTGGTAACCTGAGAAAATGCTCCACCTCATCACTCCTGGAAGCCTGCACTTTCCG
TAGACCTTAAAATCTCAGAGGTAGGGCTGCCACCAAGGTGAAGATGGGAACGCAGATGATCCATGAGTTTGCCCTGGTTTCACTGGCCCA
AGTGGTTTGTGCTAACCACGTCTGTCTTCACAGCTCTGTGTTGCCATGTGTGCTGAACAAAAAATAAAAATTATTATTGATTTTATATTT
CAAAAACTCCATTCTTTCCTAAATATTTTCAACAAAGGATTTCTTTATGCATTCTGCCTAAATACCTATGCAACTGAGCCCTTCCTTCTC
AGCTCAAGATTCGTCTGGTCTTTCCCTACAGCTTTGTGTGTGCCATGGCCACATCTCCTGGGTACAGTTCAAGGAGACATCTTTTCTAAA

>3798_3798_4_ALB-TF_ALB_chr4_74272402_ENST00000509063_TF_chr3_133495984_ENST00000402696_length(amino acids)=91AA_BP=
MSSQLCVAMCAEQKIKIIIDFIFQKLHSFLNIFNKGFLYAFCLNTYATEPFLLSSRFVWSFPTALCVPWPHLLGTVQGDIFSKRVCVIIK

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Fusion Gene PPI Analysis for ALB-TF


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ALB-TF


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ALB-TF


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource