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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ICAM1-HNRNPM (FusionGDB2 ID:38189)

Fusion Gene Summary for ICAM1-HNRNPM

check button Fusion gene summary
Fusion gene informationFusion gene name: ICAM1-HNRNPM
Fusion gene ID: 38189
HgeneTgene
Gene symbol

ICAM1

HNRNPM

Gene ID

3383

4670

Gene nameintercellular adhesion molecule 1heterogeneous nuclear ribonucleoprotein M
SynonymsBB2|CD54|P3.58CEAR|HNRNPM4|HNRPM|HNRPM4|HTGR1|NAGR1|hnRNP M
Cytomap

19p13.2

19p13.2

Type of geneprotein-codingprotein-coding
Descriptionintercellular adhesion molecule 1ICAM-1cell surface glycoprotein P3.58epididymis secretory sperm binding proteinintercellular adhesion molecule 1 (CD54), human rhinovirus receptormajor group rhinovirus receptorheterogeneous nuclear ribonucleoprotein MCEA receptorN-acetylglucosamine receptor 1heterogenous nuclear ribonucleoprotein M4hnRNA-binding protein M4
Modification date2020032920200322
UniProtAcc.

P52272

Ensembl transtripts involved in fusion geneENST00000264832, ENST00000423829, 
ENST00000585443, 		ENST00000602219, 
ENST00000325495, ENST00000348943, 
Fusion gene scores* DoF score8 X 6 X 5=24016 X 16 X 5=1280
# samples 918
** MAII scorelog2(9/240*10)=-1.41503749927884
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/1280*10)=-2.83007499855769
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ICAM1 [Title/Abstract] AND HNRNPM [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointICAM1(10385704)-HNRNPM(8550487), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneICAM1

GO:0007155

cell adhesion

16809613

HgeneICAM1

GO:0044406

adhesion of symbiont to host

2538243

HgeneICAM1

GO:0046813

receptor-mediated virion attachment to host cell

2538243

HgeneICAM1

GO:1902042

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

10903502

HgeneICAM1

GO:1904646

cellular response to amyloid-beta

11078691

HgeneICAM1

GO:2000352

negative regulation of endothelial cell apoptotic process

10903502


check buttonFusion gene breakpoints across ICAM1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across HNRNPM (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-77-7338-01AICAM1chr19

10385704

-HNRNPMchr19

8550487

+
ChimerDB4LUSCTCGA-77-7338-01AICAM1chr19

10385704

+HNRNPMchr19

8550487

+
ChimerDB4LUSCTCGA-77-7338ICAM1chr19

10385704

+HNRNPMchr19

8550486

+
ChimerDB4LUSCTCGA-77-7338ICAM1chr19

10385704

+HNRNPMchr19

8550487

+


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Fusion Gene ORF analysis for ICAM1-HNRNPM

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000264832ENST00000602219ICAM1chr19

10385704

+HNRNPMchr19

8550487

+
5CDS-intronENST00000264832ENST00000602219ICAM1chr19

10385704

+HNRNPMchr19

8550486

+
In-frameENST00000264832ENST00000325495ICAM1chr19

10385704

+HNRNPMchr19

8550487

+
In-frameENST00000264832ENST00000325495ICAM1chr19

10385704

+HNRNPMchr19

8550486

+
In-frameENST00000264832ENST00000348943ICAM1chr19

10385704

+HNRNPMchr19

8550487

+
In-frameENST00000264832ENST00000348943ICAM1chr19

10385704

+HNRNPMchr19

8550486

+
intron-3CDSENST00000423829ENST00000325495ICAM1chr19

10385704

+HNRNPMchr19

8550487

+
intron-3CDSENST00000423829ENST00000325495ICAM1chr19

10385704

+HNRNPMchr19

8550486

+
intron-3CDSENST00000423829ENST00000348943ICAM1chr19

10385704

+HNRNPMchr19

8550487

+
intron-3CDSENST00000423829ENST00000348943ICAM1chr19

10385704

+HNRNPMchr19

8550486

+
intron-3CDSENST00000585443ENST00000325495ICAM1chr19

10385704

+HNRNPMchr19

8550487

+
intron-3CDSENST00000585443ENST00000325495ICAM1chr19

10385704

+HNRNPMchr19

8550486

+
intron-3CDSENST00000585443ENST00000348943ICAM1chr19

10385704

+HNRNPMchr19

8550487

+
intron-3CDSENST00000585443ENST00000348943ICAM1chr19

10385704

+HNRNPMchr19

8550486

+
intron-intronENST00000423829ENST00000602219ICAM1chr19

10385704

+HNRNPMchr19

8550487

+
intron-intronENST00000423829ENST00000602219ICAM1chr19

10385704

+HNRNPMchr19

8550486

+
intron-intronENST00000585443ENST00000602219ICAM1chr19

10385704

+HNRNPMchr19

8550487

+
intron-intronENST00000585443ENST00000602219ICAM1chr19

10385704

+HNRNPMchr19

8550486

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000264832ICAM1chr1910385704+ENST00000348943HNRNPMchr198550487+19356561751674499
ENST00000264832ICAM1chr1910385704+ENST00000325495HNRNPMchr198550487+19356561751674499
ENST00000264832ICAM1chr1910385704+ENST00000348943HNRNPMchr198550486+19356561751674499
ENST00000264832ICAM1chr1910385704+ENST00000325495HNRNPMchr198550486+19356561751674499

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000264832ENST00000348943ICAM1chr1910385704+HNRNPMchr198550487+0.0073243690.9926756
ENST00000264832ENST00000325495ICAM1chr1910385704+HNRNPMchr198550487+0.0073243690.9926756
ENST00000264832ENST00000348943ICAM1chr1910385704+HNRNPMchr198550486+0.0073243690.9926756
ENST00000264832ENST00000325495ICAM1chr1910385704+HNRNPMchr198550486+0.0073243690.9926756

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Fusion Genomic Features for ICAM1-HNRNPM


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ICAM1chr1910385704+HNRNPMchr198550486+1.18E-081
ICAM1chr1910385704+HNRNPMchr198550486+1.18E-081
ICAM1chr1910385704+HNRNPMchr198550486+1.18E-081
ICAM1chr1910385704+HNRNPMchr198550486+1.18E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ICAM1-HNRNPM


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:10385704/chr19:8550487)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.HNRNPM

P52272

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneICAM1chr19:10385704chr19:8550486ENST00000264832+2741_103110533.0DomainNote=Ig-like C2-type 1
HgeneICAM1chr19:10385704chr19:8550487ENST00000264832+2741_103110533.0DomainNote=Ig-like C2-type 1
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216390_396391731.0Compositional biasNote=Poly-Gly
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216612_616391731.0Compositional biasNote=Poly-Gly
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317390_396352692.0Compositional biasNote=Poly-Gly
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317612_616352692.0Compositional biasNote=Poly-Gly
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216390_396391731.0Compositional biasNote=Poly-Gly
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216612_616391731.0Compositional biasNote=Poly-Gly
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317390_396352692.0Compositional biasNote=Poly-Gly
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317612_616352692.0Compositional biasNote=Poly-Gly
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216653_729391731.0DomainRRM 3
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317653_729352692.0DomainRRM 3
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216653_729391731.0DomainRRM 3
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317653_729352692.0DomainRRM 3
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216400_608391731.0RegionNote=27 X 6 AA repeats of [GEVSTPAN]-[ILMV]-[DE]-[RH]-[MLVI]-[GAV]
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317400_608352692.0RegionNote=27 X 6 AA repeats of [GEVSTPAN]-[ILMV]-[DE]-[RH]-[MLVI]-[GAV]
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216400_608391731.0RegionNote=27 X 6 AA repeats of [GEVSTPAN]-[ILMV]-[DE]-[RH]-[MLVI]-[GAV]
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317400_608352692.0RegionNote=27 X 6 AA repeats of [GEVSTPAN]-[ILMV]-[DE]-[RH]-[MLVI]-[GAV]
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216400_405391731.0RepeatNote=1
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216407_412391731.0RepeatNote=2
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216415_420391731.0RepeatNote=3
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216426_431391731.0RepeatNote=4
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216433_438391731.0RepeatNote=5
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216440_445391731.0RepeatNote=6
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216446_451391731.0RepeatNote=7
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216453_458391731.0RepeatNote=8
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216461_466391731.0RepeatNote=9
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216468_473391731.0RepeatNote=10
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216475_480391731.0RepeatNote=11
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216482_487391731.0RepeatNote=12
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216493_498391731.0RepeatNote=13
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216500_505391731.0RepeatNote=14
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216507_512391731.0RepeatNote=15
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216514_519391731.0RepeatNote=16
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216521_526391731.0RepeatNote=17
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216528_533391731.0RepeatNote=18
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216540_545391731.0RepeatNote=19
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216547_552391731.0RepeatNote=20
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216554_559391731.0RepeatNote=21
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216562_566391731.0RepeatNote=22
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216567_572391731.0RepeatNote=23
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216575_579391731.0RepeatNote=24
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216580_585391731.0RepeatNote=25
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216588_593391731.0RepeatNote=26
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216603_608391731.0RepeatNote=27
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317400_405352692.0RepeatNote=1
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317407_412352692.0RepeatNote=2
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317415_420352692.0RepeatNote=3
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317426_431352692.0RepeatNote=4
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317433_438352692.0RepeatNote=5
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317440_445352692.0RepeatNote=6
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317446_451352692.0RepeatNote=7
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317453_458352692.0RepeatNote=8
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317461_466352692.0RepeatNote=9
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317468_473352692.0RepeatNote=10
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317475_480352692.0RepeatNote=11
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317482_487352692.0RepeatNote=12
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317493_498352692.0RepeatNote=13
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317500_505352692.0RepeatNote=14
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317507_512352692.0RepeatNote=15
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317514_519352692.0RepeatNote=16
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317521_526352692.0RepeatNote=17
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317528_533352692.0RepeatNote=18
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317540_545352692.0RepeatNote=19
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317547_552352692.0RepeatNote=20
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317554_559352692.0RepeatNote=21
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317562_566352692.0RepeatNote=22
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317567_572352692.0RepeatNote=23
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317575_579352692.0RepeatNote=24
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317580_585352692.0RepeatNote=25
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317588_593352692.0RepeatNote=26
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317603_608352692.0RepeatNote=27
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216400_405391731.0RepeatNote=1
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216407_412391731.0RepeatNote=2
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216415_420391731.0RepeatNote=3
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216426_431391731.0RepeatNote=4
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216433_438391731.0RepeatNote=5
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216440_445391731.0RepeatNote=6
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216446_451391731.0RepeatNote=7
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216453_458391731.0RepeatNote=8
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216461_466391731.0RepeatNote=9
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216468_473391731.0RepeatNote=10
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216475_480391731.0RepeatNote=11
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216482_487391731.0RepeatNote=12
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216493_498391731.0RepeatNote=13
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216500_505391731.0RepeatNote=14
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216507_512391731.0RepeatNote=15
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216514_519391731.0RepeatNote=16
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216521_526391731.0RepeatNote=17
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216528_533391731.0RepeatNote=18
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216540_545391731.0RepeatNote=19
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216547_552391731.0RepeatNote=20
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216554_559391731.0RepeatNote=21
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216562_566391731.0RepeatNote=22
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216567_572391731.0RepeatNote=23
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216575_579391731.0RepeatNote=24
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216580_585391731.0RepeatNote=25
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216588_593391731.0RepeatNote=26
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216603_608391731.0RepeatNote=27
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317400_405352692.0RepeatNote=1
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317407_412352692.0RepeatNote=2
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317415_420352692.0RepeatNote=3
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317426_431352692.0RepeatNote=4
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317433_438352692.0RepeatNote=5
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317440_445352692.0RepeatNote=6
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317446_451352692.0RepeatNote=7
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317453_458352692.0RepeatNote=8
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317461_466352692.0RepeatNote=9
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317468_473352692.0RepeatNote=10
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317475_480352692.0RepeatNote=11
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317482_487352692.0RepeatNote=12
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317493_498352692.0RepeatNote=13
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317500_505352692.0RepeatNote=14
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317507_512352692.0RepeatNote=15
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317514_519352692.0RepeatNote=16
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317521_526352692.0RepeatNote=17
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317528_533352692.0RepeatNote=18
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317540_545352692.0RepeatNote=19
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317547_552352692.0RepeatNote=20
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317554_559352692.0RepeatNote=21
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317562_566352692.0RepeatNote=22
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317567_572352692.0RepeatNote=23
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317575_579352692.0RepeatNote=24
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317580_585352692.0RepeatNote=25
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317588_593352692.0RepeatNote=26
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317603_608352692.0RepeatNote=27

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneICAM1chr19:10385704chr19:8550486ENST00000264832+27128_193110533.0DomainNote=Ig-like C2-type 2
HgeneICAM1chr19:10385704chr19:8550486ENST00000264832+27230_297110533.0DomainNote=Ig-like C2-type 3
HgeneICAM1chr19:10385704chr19:8550486ENST00000264832+27325_378110533.0DomainNote=Ig-like C2-type 4
HgeneICAM1chr19:10385704chr19:8550486ENST00000264832+27412_464110533.0DomainNote=Ig-like C2-type 5
HgeneICAM1chr19:10385704chr19:8550487ENST00000264832+27128_193110533.0DomainNote=Ig-like C2-type 2
HgeneICAM1chr19:10385704chr19:8550487ENST00000264832+27230_297110533.0DomainNote=Ig-like C2-type 3
HgeneICAM1chr19:10385704chr19:8550487ENST00000264832+27325_378110533.0DomainNote=Ig-like C2-type 4
HgeneICAM1chr19:10385704chr19:8550487ENST00000264832+27412_464110533.0DomainNote=Ig-like C2-type 5
HgeneICAM1chr19:10385704chr19:8550486ENST00000264832+27152_154110533.0MotifCell attachment site%3B atypical
HgeneICAM1chr19:10385704chr19:8550487ENST00000264832+27152_154110533.0MotifCell attachment site%3B atypical
HgeneICAM1chr19:10385704chr19:8550486ENST00000264832+2728_480110533.0Topological domainExtracellular
HgeneICAM1chr19:10385704chr19:8550486ENST00000264832+27504_532110533.0Topological domainCytoplasmic
HgeneICAM1chr19:10385704chr19:8550487ENST00000264832+2728_480110533.0Topological domainExtracellular
HgeneICAM1chr19:10385704chr19:8550487ENST00000264832+27504_532110533.0Topological domainCytoplasmic
HgeneICAM1chr19:10385704chr19:8550486ENST00000264832+27481_503110533.0TransmembraneHelical
HgeneICAM1chr19:10385704chr19:8550487ENST00000264832+27481_503110533.0TransmembraneHelical
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003254951216204_281391731.0DomainRRM 2
TgeneHNRNPMchr19:10385704chr19:8550486ENST00000325495121671_149391731.0DomainRRM 1
TgeneHNRNPMchr19:10385704chr19:8550486ENST000003489431317204_281352692.0DomainRRM 2
TgeneHNRNPMchr19:10385704chr19:8550486ENST00000348943131771_149352692.0DomainRRM 1
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003254951216204_281391731.0DomainRRM 2
TgeneHNRNPMchr19:10385704chr19:8550487ENST00000325495121671_149391731.0DomainRRM 1
TgeneHNRNPMchr19:10385704chr19:8550487ENST000003489431317204_281352692.0DomainRRM 2
TgeneHNRNPMchr19:10385704chr19:8550487ENST00000348943131771_149352692.0DomainRRM 1


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Fusion Gene Sequence for ICAM1-HNRNPM


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>38189_38189_1_ICAM1-HNRNPM_ICAM1_chr19_10385704_ENST00000264832_HNRNPM_chr19_8550486_ENST00000325495_length(transcript)=1935nt_BP=656nt
GTGATTCAAGCTTAGCCTGGCCGGGAAACGGGAGGCGTGGAGGCCGGGAGCAGCCCCCGGGGTCATCGCCCTGCCACCGCCGCCCGATTG
CTTTAGCTTGGAAATTCCGGAGCTGAAGCGGCCAGCGAGGGAGGATGACCCTCTCGGCCCGGGCACCCTGTCAGTCCGGAAATAACTGCA
GCATTTGTTCCGGAGGGGAAGGCGCGAGGTTTCCGGGAAAGCAGCACCGCCCCTTGGCCCCCAGGTGGCTAGCGCTATAAAGGATCACGC
GCCCCAGTCGACGCTGAGCTCCTCTGCTACTCAGAGTTGCAACCTCAGCCTCGCTATGGCTCCCAGCAGCCCCCGGCCCGCGCTGCCCGC
ACTCCTGGTCCTGCTCGGGGCTCTGTTCCCAGGACCTGGCAATGCCCAGACATCTGTGTCCCCCTCAAAAGTCATCCTGCCCCGGGGAGG
CTCCGTGCTGGTGACATGCAGCACCTCCTGTGACCAGCCCAAGTTGTTGGGCATAGAGACCCCGTTGCCTAAAAAGGAGTTGCTCCTGCC
TGGGAACAACCGGAAGGTGTATGAACTGAGCAATGTGCAAGAAGATAGCCAACCAATGTGCTATTCAAACTGCCCTGATGGGCAGTCAAC
AGCTAAAACCTTCCTCACCGTGTACTGTGGAGGTGGAGGAAGCGTCCCTGGGATCGAGAGGATGGGTCCTGGCATTGACCGCCTCGGGGG
TGCCGGCATGGAGCGCATGGGCGCGGGCCTGGGCCACGGCATGGATCGCGTGGGCTCCGAGATCGAGCGCATGGGCCTGGTCATGGACCG
CATGGGCTCCGTGGAGCGCATGGGCTCCGGCATTGAGCGCATGGGCCCGCTGGGCCTCGACCACATGGCCTCCAGCATTGAGCGCATGGG
CCAGACCATGGAGCGCATTGGCTCTGGCGTGGAGCGCATGGGTGCCGGCATGGGCTTCGGCCTTGAGCGCATGGCCGCTCCCATCGACCG
TGTGGGCCAGACCATTGAGCGCATGGGCTCTGGCGTGGAGCGCATGGGCCCTGCCATCGAGCGCATGGGCCTGAGCATGGAGCGCATGGT
GCCCGCAGGTATGGGAGCTGGCCTGGAGCGCATGGGCCCCGTGATGGATCGCATGGCCACCGGCCTGGAGCGCATGGGCGCCAACAATCT
GGAGCGGATGGGCCTGGAGCGCATGGGCGCCAACAGCCTCGAGCGCATGGGCCTGGAGCGCATGGGTGCCAACAGCCTCGAGCGCATGGG
CCCTGCCATGGGCCCGGCCCTGGGCGCTGGCATTGAGCGCATGGGCCTGGCCATGGGTGGCGGTGGCGGTGCCAGCTTTGACCGTGCCAT
CGAGATGGAGCGTGGCAACTTCGGAGGAAGCTTCGCAGGTTCCTTTGGTGGAGCTGGAGGCCATGCTCCTGGGGTGGCCAGGAAGGCCTG
CCAGATATTTGTGAGAAATCTGCCATTCGATTTCACATGGAAGATGCTAAAGGACAAATTCAACGAGTGCGGCCACGTGCTGTACGCCGA
CATCAAGATGGAGAATGGGAAGTCCAAGGGGTGTGGCGTGGTTAAGTTCGAGTCGCCAGAGGTGGCCGAGAGAGCCTGCCGGATGATGAA
TGGCATGAAGCTGAGTGGCCGAGAGATTGACGTTCGAATTGATAGAAACGCTTAAGCAGTTGCCTTTTTTAAACATCGATACGAGACCTC
TGAATTTGTATTTTTTCTTGTTAACCATTTTAATTTGTTGGCTGGATGTATAAAGATGTTTAAAAAATTCAGTTGCTTTTTGGGGTAATT
TGAATTACTTTTTTAATGACTGGGGTTCCATTTGACTGTTTGCATTGAGATTGCAATGTGCGCAATTTTTTTTGTAGTTGTGGCATCTTG

>38189_38189_1_ICAM1-HNRNPM_ICAM1_chr19_10385704_ENST00000264832_HNRNPM_chr19_8550486_ENST00000325495_length(amino acids)=499AA_BP=161
MQHLFRRGRREVSGKAAPPLGPQVASAIKDHAPQSTLSSSATQSCNLSLAMAPSSPRPALPALLVLLGALFPGPGNAQTSVSPSKVILPR
GGSVLVTCSTSCDQPKLLGIETPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYCGGGGSVPGIERMGPGIDRL
GGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPI
DRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLER
MGPAMGPALGAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLY

--------------------------------------------------------------
>38189_38189_2_ICAM1-HNRNPM_ICAM1_chr19_10385704_ENST00000264832_HNRNPM_chr19_8550486_ENST00000348943_length(transcript)=1935nt_BP=656nt
GTGATTCAAGCTTAGCCTGGCCGGGAAACGGGAGGCGTGGAGGCCGGGAGCAGCCCCCGGGGTCATCGCCCTGCCACCGCCGCCCGATTG
CTTTAGCTTGGAAATTCCGGAGCTGAAGCGGCCAGCGAGGGAGGATGACCCTCTCGGCCCGGGCACCCTGTCAGTCCGGAAATAACTGCA
GCATTTGTTCCGGAGGGGAAGGCGCGAGGTTTCCGGGAAAGCAGCACCGCCCCTTGGCCCCCAGGTGGCTAGCGCTATAAAGGATCACGC
GCCCCAGTCGACGCTGAGCTCCTCTGCTACTCAGAGTTGCAACCTCAGCCTCGCTATGGCTCCCAGCAGCCCCCGGCCCGCGCTGCCCGC
ACTCCTGGTCCTGCTCGGGGCTCTGTTCCCAGGACCTGGCAATGCCCAGACATCTGTGTCCCCCTCAAAAGTCATCCTGCCCCGGGGAGG
CTCCGTGCTGGTGACATGCAGCACCTCCTGTGACCAGCCCAAGTTGTTGGGCATAGAGACCCCGTTGCCTAAAAAGGAGTTGCTCCTGCC
TGGGAACAACCGGAAGGTGTATGAACTGAGCAATGTGCAAGAAGATAGCCAACCAATGTGCTATTCAAACTGCCCTGATGGGCAGTCAAC
AGCTAAAACCTTCCTCACCGTGTACTGTGGAGGTGGAGGAAGCGTCCCTGGGATCGAGAGGATGGGTCCTGGCATTGACCGCCTCGGGGG
TGCCGGCATGGAGCGCATGGGCGCGGGCCTGGGCCACGGCATGGATCGCGTGGGCTCCGAGATCGAGCGCATGGGCCTGGTCATGGACCG
CATGGGCTCCGTGGAGCGCATGGGCTCCGGCATTGAGCGCATGGGCCCGCTGGGCCTCGACCACATGGCCTCCAGCATTGAGCGCATGGG
CCAGACCATGGAGCGCATTGGCTCTGGCGTGGAGCGCATGGGTGCCGGCATGGGCTTCGGCCTTGAGCGCATGGCCGCTCCCATCGACCG
TGTGGGCCAGACCATTGAGCGCATGGGCTCTGGCGTGGAGCGCATGGGCCCTGCCATCGAGCGCATGGGCCTGAGCATGGAGCGCATGGT
GCCCGCAGGTATGGGAGCTGGCCTGGAGCGCATGGGCCCCGTGATGGATCGCATGGCCACCGGCCTGGAGCGCATGGGCGCCAACAATCT
GGAGCGGATGGGCCTGGAGCGCATGGGCGCCAACAGCCTCGAGCGCATGGGCCTGGAGCGCATGGGTGCCAACAGCCTCGAGCGCATGGG
CCCTGCCATGGGCCCGGCCCTGGGCGCTGGCATTGAGCGCATGGGCCTGGCCATGGGTGGCGGTGGCGGTGCCAGCTTTGACCGTGCCAT
CGAGATGGAGCGTGGCAACTTCGGAGGAAGCTTCGCAGGTTCCTTTGGTGGAGCTGGAGGCCATGCTCCTGGGGTGGCCAGGAAGGCCTG
CCAGATATTTGTGAGAAATCTGCCATTCGATTTCACATGGAAGATGCTAAAGGACAAATTCAACGAGTGCGGCCACGTGCTGTACGCCGA
CATCAAGATGGAGAATGGGAAGTCCAAGGGGTGTGGCGTGGTTAAGTTCGAGTCGCCAGAGGTGGCCGAGAGAGCCTGCCGGATGATGAA
TGGCATGAAGCTGAGTGGCCGAGAGATTGACGTTCGAATTGATAGAAACGCTTAAGCAGTTGCCTTTTTTAAACATCGATACGAGACCTC
TGAATTTGTATTTTTTCTTGTTAACCATTTTAATTTGTTGGCTGGATGTATAAAGATGTTTAAAAAATTCAGTTGCTTTTTGGGGTAATT
TGAATTACTTTTTTAATGACTGGGGTTCCATTTGACTGTTTGCATTGAGATTGCAATGTGCGCAATTTTTTTTGTAGTTGTGGCATCTTG

>38189_38189_2_ICAM1-HNRNPM_ICAM1_chr19_10385704_ENST00000264832_HNRNPM_chr19_8550486_ENST00000348943_length(amino acids)=499AA_BP=161
MQHLFRRGRREVSGKAAPPLGPQVASAIKDHAPQSTLSSSATQSCNLSLAMAPSSPRPALPALLVLLGALFPGPGNAQTSVSPSKVILPR
GGSVLVTCSTSCDQPKLLGIETPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYCGGGGSVPGIERMGPGIDRL
GGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPI
DRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLER
MGPAMGPALGAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLY

--------------------------------------------------------------
>38189_38189_3_ICAM1-HNRNPM_ICAM1_chr19_10385704_ENST00000264832_HNRNPM_chr19_8550487_ENST00000325495_length(transcript)=1935nt_BP=656nt
GTGATTCAAGCTTAGCCTGGCCGGGAAACGGGAGGCGTGGAGGCCGGGAGCAGCCCCCGGGGTCATCGCCCTGCCACCGCCGCCCGATTG
CTTTAGCTTGGAAATTCCGGAGCTGAAGCGGCCAGCGAGGGAGGATGACCCTCTCGGCCCGGGCACCCTGTCAGTCCGGAAATAACTGCA
GCATTTGTTCCGGAGGGGAAGGCGCGAGGTTTCCGGGAAAGCAGCACCGCCCCTTGGCCCCCAGGTGGCTAGCGCTATAAAGGATCACGC
GCCCCAGTCGACGCTGAGCTCCTCTGCTACTCAGAGTTGCAACCTCAGCCTCGCTATGGCTCCCAGCAGCCCCCGGCCCGCGCTGCCCGC
ACTCCTGGTCCTGCTCGGGGCTCTGTTCCCAGGACCTGGCAATGCCCAGACATCTGTGTCCCCCTCAAAAGTCATCCTGCCCCGGGGAGG
CTCCGTGCTGGTGACATGCAGCACCTCCTGTGACCAGCCCAAGTTGTTGGGCATAGAGACCCCGTTGCCTAAAAAGGAGTTGCTCCTGCC
TGGGAACAACCGGAAGGTGTATGAACTGAGCAATGTGCAAGAAGATAGCCAACCAATGTGCTATTCAAACTGCCCTGATGGGCAGTCAAC
AGCTAAAACCTTCCTCACCGTGTACTGTGGAGGTGGAGGAAGCGTCCCTGGGATCGAGAGGATGGGTCCTGGCATTGACCGCCTCGGGGG
TGCCGGCATGGAGCGCATGGGCGCGGGCCTGGGCCACGGCATGGATCGCGTGGGCTCCGAGATCGAGCGCATGGGCCTGGTCATGGACCG
CATGGGCTCCGTGGAGCGCATGGGCTCCGGCATTGAGCGCATGGGCCCGCTGGGCCTCGACCACATGGCCTCCAGCATTGAGCGCATGGG
CCAGACCATGGAGCGCATTGGCTCTGGCGTGGAGCGCATGGGTGCCGGCATGGGCTTCGGCCTTGAGCGCATGGCCGCTCCCATCGACCG
TGTGGGCCAGACCATTGAGCGCATGGGCTCTGGCGTGGAGCGCATGGGCCCTGCCATCGAGCGCATGGGCCTGAGCATGGAGCGCATGGT
GCCCGCAGGTATGGGAGCTGGCCTGGAGCGCATGGGCCCCGTGATGGATCGCATGGCCACCGGCCTGGAGCGCATGGGCGCCAACAATCT
GGAGCGGATGGGCCTGGAGCGCATGGGCGCCAACAGCCTCGAGCGCATGGGCCTGGAGCGCATGGGTGCCAACAGCCTCGAGCGCATGGG
CCCTGCCATGGGCCCGGCCCTGGGCGCTGGCATTGAGCGCATGGGCCTGGCCATGGGTGGCGGTGGCGGTGCCAGCTTTGACCGTGCCAT
CGAGATGGAGCGTGGCAACTTCGGAGGAAGCTTCGCAGGTTCCTTTGGTGGAGCTGGAGGCCATGCTCCTGGGGTGGCCAGGAAGGCCTG
CCAGATATTTGTGAGAAATCTGCCATTCGATTTCACATGGAAGATGCTAAAGGACAAATTCAACGAGTGCGGCCACGTGCTGTACGCCGA
CATCAAGATGGAGAATGGGAAGTCCAAGGGGTGTGGCGTGGTTAAGTTCGAGTCGCCAGAGGTGGCCGAGAGAGCCTGCCGGATGATGAA
TGGCATGAAGCTGAGTGGCCGAGAGATTGACGTTCGAATTGATAGAAACGCTTAAGCAGTTGCCTTTTTTAAACATCGATACGAGACCTC
TGAATTTGTATTTTTTCTTGTTAACCATTTTAATTTGTTGGCTGGATGTATAAAGATGTTTAAAAAATTCAGTTGCTTTTTGGGGTAATT
TGAATTACTTTTTTAATGACTGGGGTTCCATTTGACTGTTTGCATTGAGATTGCAATGTGCGCAATTTTTTTTGTAGTTGTGGCATCTTG

>38189_38189_3_ICAM1-HNRNPM_ICAM1_chr19_10385704_ENST00000264832_HNRNPM_chr19_8550487_ENST00000325495_length(amino acids)=499AA_BP=161
MQHLFRRGRREVSGKAAPPLGPQVASAIKDHAPQSTLSSSATQSCNLSLAMAPSSPRPALPALLVLLGALFPGPGNAQTSVSPSKVILPR
GGSVLVTCSTSCDQPKLLGIETPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYCGGGGSVPGIERMGPGIDRL
GGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPI
DRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLER
MGPAMGPALGAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLY

--------------------------------------------------------------
>38189_38189_4_ICAM1-HNRNPM_ICAM1_chr19_10385704_ENST00000264832_HNRNPM_chr19_8550487_ENST00000348943_length(transcript)=1935nt_BP=656nt
GTGATTCAAGCTTAGCCTGGCCGGGAAACGGGAGGCGTGGAGGCCGGGAGCAGCCCCCGGGGTCATCGCCCTGCCACCGCCGCCCGATTG
CTTTAGCTTGGAAATTCCGGAGCTGAAGCGGCCAGCGAGGGAGGATGACCCTCTCGGCCCGGGCACCCTGTCAGTCCGGAAATAACTGCA
GCATTTGTTCCGGAGGGGAAGGCGCGAGGTTTCCGGGAAAGCAGCACCGCCCCTTGGCCCCCAGGTGGCTAGCGCTATAAAGGATCACGC
GCCCCAGTCGACGCTGAGCTCCTCTGCTACTCAGAGTTGCAACCTCAGCCTCGCTATGGCTCCCAGCAGCCCCCGGCCCGCGCTGCCCGC
ACTCCTGGTCCTGCTCGGGGCTCTGTTCCCAGGACCTGGCAATGCCCAGACATCTGTGTCCCCCTCAAAAGTCATCCTGCCCCGGGGAGG
CTCCGTGCTGGTGACATGCAGCACCTCCTGTGACCAGCCCAAGTTGTTGGGCATAGAGACCCCGTTGCCTAAAAAGGAGTTGCTCCTGCC
TGGGAACAACCGGAAGGTGTATGAACTGAGCAATGTGCAAGAAGATAGCCAACCAATGTGCTATTCAAACTGCCCTGATGGGCAGTCAAC
AGCTAAAACCTTCCTCACCGTGTACTGTGGAGGTGGAGGAAGCGTCCCTGGGATCGAGAGGATGGGTCCTGGCATTGACCGCCTCGGGGG
TGCCGGCATGGAGCGCATGGGCGCGGGCCTGGGCCACGGCATGGATCGCGTGGGCTCCGAGATCGAGCGCATGGGCCTGGTCATGGACCG
CATGGGCTCCGTGGAGCGCATGGGCTCCGGCATTGAGCGCATGGGCCCGCTGGGCCTCGACCACATGGCCTCCAGCATTGAGCGCATGGG
CCAGACCATGGAGCGCATTGGCTCTGGCGTGGAGCGCATGGGTGCCGGCATGGGCTTCGGCCTTGAGCGCATGGCCGCTCCCATCGACCG
TGTGGGCCAGACCATTGAGCGCATGGGCTCTGGCGTGGAGCGCATGGGCCCTGCCATCGAGCGCATGGGCCTGAGCATGGAGCGCATGGT
GCCCGCAGGTATGGGAGCTGGCCTGGAGCGCATGGGCCCCGTGATGGATCGCATGGCCACCGGCCTGGAGCGCATGGGCGCCAACAATCT
GGAGCGGATGGGCCTGGAGCGCATGGGCGCCAACAGCCTCGAGCGCATGGGCCTGGAGCGCATGGGTGCCAACAGCCTCGAGCGCATGGG
CCCTGCCATGGGCCCGGCCCTGGGCGCTGGCATTGAGCGCATGGGCCTGGCCATGGGTGGCGGTGGCGGTGCCAGCTTTGACCGTGCCAT
CGAGATGGAGCGTGGCAACTTCGGAGGAAGCTTCGCAGGTTCCTTTGGTGGAGCTGGAGGCCATGCTCCTGGGGTGGCCAGGAAGGCCTG
CCAGATATTTGTGAGAAATCTGCCATTCGATTTCACATGGAAGATGCTAAAGGACAAATTCAACGAGTGCGGCCACGTGCTGTACGCCGA
CATCAAGATGGAGAATGGGAAGTCCAAGGGGTGTGGCGTGGTTAAGTTCGAGTCGCCAGAGGTGGCCGAGAGAGCCTGCCGGATGATGAA
TGGCATGAAGCTGAGTGGCCGAGAGATTGACGTTCGAATTGATAGAAACGCTTAAGCAGTTGCCTTTTTTAAACATCGATACGAGACCTC
TGAATTTGTATTTTTTCTTGTTAACCATTTTAATTTGTTGGCTGGATGTATAAAGATGTTTAAAAAATTCAGTTGCTTTTTGGGGTAATT
TGAATTACTTTTTTAATGACTGGGGTTCCATTTGACTGTTTGCATTGAGATTGCAATGTGCGCAATTTTTTTTGTAGTTGTGGCATCTTG

>38189_38189_4_ICAM1-HNRNPM_ICAM1_chr19_10385704_ENST00000264832_HNRNPM_chr19_8550487_ENST00000348943_length(amino acids)=499AA_BP=161
MQHLFRRGRREVSGKAAPPLGPQVASAIKDHAPQSTLSSSATQSCNLSLAMAPSSPRPALPALLVLLGALFPGPGNAQTSVSPSKVILPR
GGSVLVTCSTSCDQPKLLGIETPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYCGGGGSVPGIERMGPGIDRL
GGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPI
DRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLER
MGPAMGPALGAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLY

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ICAM1-HNRNPM


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ICAM1-HNRNPM


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ICAM1-HNRNPM


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource