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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:IFT20-SUZ12 (FusionGDB2 ID:38417)

Fusion Gene Summary for IFT20-SUZ12

check button Fusion gene summary
Fusion gene informationFusion gene name: IFT20-SUZ12
Fusion gene ID: 38417
HgeneTgene
Gene symbol

IFT20

SUZ12

Gene ID

90410

23512

Gene nameintraflagellar transport 20SUZ12 polycomb repressive complex 2 subunit
Synonyms-CHET9|IMMAS|JJAZ1
Cytomap

17q11.2

17q11.2

Type of geneprotein-codingprotein-coding
Descriptionintraflagellar transport protein 20 homologintraflagellar transport 20 homologintraflagellar transport protein IFT20polycomb protein SUZ12chET 9 proteinchromatin precipitated E2F target 9 proteinjoined to JAZF1 proteinsuppressor of zeste 12 protein homolog
Modification date2020032720200313
UniProtAcc.

Q15022

Ensembl transtripts involved in fusion geneENST00000357896, ENST00000578122, 
ENST00000585089, ENST00000395418, 
ENST00000579419, ENST00000585313, 
ENST00000578985, 		ENST00000322652, 
ENST00000580398, 
Fusion gene scores* DoF score3 X 3 X 3=2710 X 8 X 5=400
# samples 38
** MAII scorelog2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(8/400*10)=-2.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: IFT20 [Title/Abstract] AND SUZ12 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointIFT20(26656199)-SUZ12(30267305), # samples:2
Anticipated loss of major functional domain due to fusion event.IFT20-SUZ12 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
IFT20-SUZ12 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
IFT20-SUZ12 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
IFT20-SUZ12 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across IFT20 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SUZ12 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A08F-01AIFT20chr17

26656199

-SUZ12chr17

30267305

+


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Fusion Gene ORF analysis for IFT20-SUZ12

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000357896ENST00000322652IFT20chr17

26656199

-SUZ12chr17

30267305

+
Frame-shiftENST00000357896ENST00000580398IFT20chr17

26656199

-SUZ12chr17

30267305

+
Frame-shiftENST00000578122ENST00000322652IFT20chr17

26656199

-SUZ12chr17

30267305

+
Frame-shiftENST00000578122ENST00000580398IFT20chr17

26656199

-SUZ12chr17

30267305

+
Frame-shiftENST00000585089ENST00000322652IFT20chr17

26656199

-SUZ12chr17

30267305

+
Frame-shiftENST00000585089ENST00000580398IFT20chr17

26656199

-SUZ12chr17

30267305

+
In-frameENST00000395418ENST00000322652IFT20chr17

26656199

-SUZ12chr17

30267305

+
In-frameENST00000395418ENST00000580398IFT20chr17

26656199

-SUZ12chr17

30267305

+
In-frameENST00000579419ENST00000322652IFT20chr17

26656199

-SUZ12chr17

30267305

+
In-frameENST00000579419ENST00000580398IFT20chr17

26656199

-SUZ12chr17

30267305

+
In-frameENST00000585313ENST00000322652IFT20chr17

26656199

-SUZ12chr17

30267305

+
In-frameENST00000585313ENST00000580398IFT20chr17

26656199

-SUZ12chr17

30267305

+
intron-3CDSENST00000578985ENST00000322652IFT20chr17

26656199

-SUZ12chr17

30267305

+
intron-3CDSENST00000578985ENST00000580398IFT20chr17

26656199

-SUZ12chr17

30267305

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000579419IFT20chr1726656199-ENST00000322652SUZ12chr1730267305+44434555112400629
ENST00000579419IFT20chr1726656199-ENST00000580398SUZ12chr1730267305+39784555112331606
ENST00000395418IFT20chr1726656199-ENST00000322652SUZ12chr1730267305+44084204762365629
ENST00000395418IFT20chr1726656199-ENST00000580398SUZ12chr1730267305+39434204762296606
ENST00000585313IFT20chr1726656199-ENST00000322652SUZ12chr1730267305+44434555112400629
ENST00000585313IFT20chr1726656199-ENST00000580398SUZ12chr1730267305+39784555112331606

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000579419ENST00000322652IFT20chr1726656199-SUZ12chr1730267305+0.0002606790.99973935
ENST00000579419ENST00000580398IFT20chr1726656199-SUZ12chr1730267305+0.0001931890.9998068
ENST00000395418ENST00000322652IFT20chr1726656199-SUZ12chr1730267305+0.000245510.9997545
ENST00000395418ENST00000580398IFT20chr1726656199-SUZ12chr1730267305+0.0001804480.9998196
ENST00000585313ENST00000322652IFT20chr1726656199-SUZ12chr1730267305+0.0002606790.99973935
ENST00000585313ENST00000580398IFT20chr1726656199-SUZ12chr1730267305+0.0001931890.9998068

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Fusion Genomic Features for IFT20-SUZ12


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
IFT20chr1726656198-SUZ12chr1730267304+0.052380050.94762
IFT20chr1726656198-SUZ12chr1730267304+0.052380050.94762

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for IFT20-SUZ12


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:26656199/chr17:30267305)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.SUZ12

Q15022

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Polycomb group (PcG) protein. Component of the PRC2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene (PubMed:15225548, PubMed:15231737, PubMed:15385962, PubMed:16618801, PubMed:17344414, PubMed:18285464, PubMed:28229514, PubMed:29499137, PubMed:31959557). The PRC2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (PubMed:12435631, PubMed:12351676, PubMed:15385962, PubMed:15099518, PubMed:15225548, PubMed:15684044, PubMed:16431907, PubMed:18086877, PubMed:18285464). Genes repressed by the PRC2 complex include HOXC8, HOXA9, MYT1 and CDKN2A (PubMed:15231737, PubMed:16618801, PubMed:17200670, PubMed:31959557). {ECO:0000269|PubMed:12351676, ECO:0000269|PubMed:12435631, ECO:0000269|PubMed:15099518, ECO:0000269|PubMed:15225548, ECO:0000269|PubMed:15231737, ECO:0000269|PubMed:15385962, ECO:0000269|PubMed:15684044, ECO:0000269|PubMed:16431907, ECO:0000269|PubMed:16618801, ECO:0000269|PubMed:17200670, ECO:0000269|PubMed:17344414, ECO:0000269|PubMed:18086877, ECO:0000269|PubMed:18285464, ECO:0000269|PubMed:28229514, ECO:0000269|PubMed:29499137, ECO:0000269|PubMed:31959557}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIFT20chr17:26656199chr17:30267305ENST00000357896-5674_114145149.0Coiled coilOntology_term=ECO:0000255
HgeneIFT20chr17:26656199chr17:30267305ENST00000585089-5674_114131159.0Coiled coilOntology_term=ECO:0000255
HgeneIFT20chr17:26656199chr17:30267305ENST00000357896-5670_132145149.0RegionIFT57-binding
HgeneIFT20chr17:26656199chr17:30267305ENST00000585089-5670_132131159.0RegionIFT57-binding
TgeneSUZ12chr17:26656199chr17:30267305ENST00000322652016563_63991740.0RegionNote=VEFS-box
TgeneSUZ12chr17:26656199chr17:30267305ENST00000322652016448_47191740.0Zinc fingerNote=C2H2-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIFT20chr17:26656199chr17:30267305ENST00000395418-4574_114105133.0Coiled coilOntology_term=ECO:0000255
HgeneIFT20chr17:26656199chr17:30267305ENST00000579419-5674_114105115.0Coiled coilOntology_term=ECO:0000255
HgeneIFT20chr17:26656199chr17:30267305ENST00000585313-5674_114105133.0Coiled coilOntology_term=ECO:0000255
HgeneIFT20chr17:26656199chr17:30267305ENST00000395418-4570_132105133.0RegionIFT57-binding
HgeneIFT20chr17:26656199chr17:30267305ENST00000579419-5670_132105115.0RegionIFT57-binding
HgeneIFT20chr17:26656199chr17:30267305ENST00000585313-5670_132105133.0RegionIFT57-binding
TgeneSUZ12chr17:26656199chr17:30267305ENST0000032265201651_5991740.0Compositional biasNote=Poly-Ser
TgeneSUZ12chr17:26656199chr17:30267305ENST0000032265201660_6791740.0Compositional biasNote=Poly-Ala
TgeneSUZ12chr17:26656199chr17:30267305ENST000003226520167_5091740.0Compositional biasNote=Gly-rich


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Fusion Gene Sequence for IFT20-SUZ12


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>38417_38417_1_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000395418_SUZ12_chr17_30267305_ENST00000322652_length(transcript)=4408nt_BP=420nt
GCCGTGGCAGGCTGGCTGGGTACCGGCTGTCGCTGACCCAGGAGAAGCTGCCTGTCTACATCAGCCTGGGCTGCAGCGCGCTGCCGCCGC
GGGGCCGGCAGCCATGGCCAAGGACATCCTGGGTGAAGCAGGGCTACACTTTGATGAACTGAACAAGCTGAGGGTGTTGGACCCAGAGGT
TACCCAGCAGACCATAGAGCTGAAGGAAGAGTGCAAAGACTTTGTGGACAAAATTGGCCAGTTTCAGAAAATAGTTGGTGGTTTAATTGA
GCTTGTTGATCAACTTGCAAAAGAAGCAGAAAATGAAAAGATGAAGGCCATCGGTGCTCGGAACTTGCTCAAATCTATAGCAAAGCAGAG
AGAAGCTCAACAGCAGCAACTTCAAGCCCTAATAGCAGAAAAGAAAATGCAGCTAGAAAGAGCCAACACAGATCTATAGATTTCTTCGAA
CTCGGAATCTCATAGCACCAATATTTTTGCACAGAACTCTTACTTACATGTCTCATCGAAACTCCAGAACAAACATCAAAAGGAAAACAT
TTAAAGTTGATGATATGTTATCAAAAGTAGAGAAAATGAAAGGAGAGCAAGAATCTCATAGCTTGTCAGCTCATTTGCAGCTTACGTTTA
CTGGTTTCTTCCACAAAAATGATAAGCCATCACCAAACTCAGAAAATGAACAAAATTCTGTTACCCTGGAAGTCCTGCTTGTGAAAGTTT
GCCACAAAAAAAGAAAGGATGTAAGTTGTCCAATAAGGCAAGTTCCCACAGGTAAAAAGCAGGTGCCTTTGAATCCTGACCTCAATCAAA
CAAAACCCGGAAATTTCCCGTCCCTTGCAGTTTCCAGTAATGAATTTGAACCTAGTAACAGCCATATGGTGAAGTCTTACTCGTTGCTAT
TTAGAGTGACTCGTCCAGGAAGAAGAGAGTTTAATGGAATGATTAATGGAGAAACCAATGAAAATATTGATGTCAATGAAGAGCTTCCAG
CCAGAAGAAAACGAAATCGTGAGGATGGGGAAAAGACATTTGTTGCACAAATGACAGTATTTGATAAAAACAGGCGCTTACAGCTTTTAG
ATGGGGAATATGAAGTAGCCATGCAGGAAATGGAAGAATGTCCAATAAGCAAGAAAAGAGCAACATGGGAGACTATTCTTGATGGGAAGA
GGCTGCCTCCATTCGAAACATTTTCTCAGGGACCTACGTTGCAGTTCACTCTTCGTTGGACAGGAGAGACCAATGATAAATCTACGGCTC
CTATTGCCAAACCTCTTGCCACTAGAAATTCAGAGAGTCTCCATCAGGAAAACAAGCCTGGTTCAGTTAAACCTACTCAAACTATTGCTG
TTAAAGAATCATTGACTACAGATCTACAAACAAGAAAAGAAAAGGATACTCCAAATGAAAACCGACAAAAATTAAGAATATTTTATCAGT
TTCTCTATAACAACAATACAAGGCAACAAACTGAAGCAAGAGATGACCTGCATTGCCCTTGGTGTACTCTGAACTGCCGCAAACTTTATA
GTTTACTCAAGCATCTTAAACTCTGCCATAGCAGATTTATCTTCAACTATGTTTATCATCCAAAAGGTGCTAGGATAGATGTTTCTATCA
ATGAGTGTTATGATGGCTCCTATGCAGGAAATCCTCAGGATATTCATCGCCAACCTGGATTTGCTTTTAGTCGCAACGGACCAGTTAAGA
GAACACCTATCACACATATTCTTGTGTGCAGGCCAAAACGAACAAAAGCAAGCATGTCTGAATTTCTTGAATCTGAAGATGGGGAAGTAG
AACAGCAAAGAACATATAGTAGTGGCCACAATCGTCTGTATTTCCATAGTGATACCTGCTTACCTCTCCGTCCACAAGAAATGGAAGTAG
ATAGTGAAGATGAAAAGGATCCTGAATGGCTAAGAGAAAAAACCATTACACAAATTGAAGAGTTTTCTGATGTTAATGAAGGAGAGAAAG
AAGTGATGAAACTCTGGAATCTCCATGTCATGAAGCATGGGTTTATTGCTGACAATCAAATGAATCATGCCTGTATGCTGTTTGTAGAAA
ATTATGGACAGAAAATAATTAAGAAGAATTTATGTCGAAACTTCATGCTTCATCTAGTCAGCATGCATGACTTTAATCTTATTAGCATAA
TGTCAATAGATAAAGCTGTTACCAAGCTCCGTGAAATGCAGCAAAAATTAGAAAAGGGGGAATCTGCTTCCCCTGCAAACGAAGAAATAA
CTGAAGAACAAAATGGGACAGCAAATGGATTTAGTGAAATTAACTCAAAAGAGAAAGCTTTGGAAACAGATAGTGTCTCAGGGGTTTCAA
AACAGAGCAAAAAACAAAAACTCTGAAAAGCTCTAACCCCATGTTATGGACAAACACTGAAATTACATTTTAGGGAATTCATCCTCTAAG
AATTATGTTTTTGTTTTTAATCATATGTTCCAAACAGGCACTGTTAGATGAAGTAAATGATTTCAACAAGGATATTTGTATCAGGGTTCT
ACTTCACTTCATTATGCAGCATTACATGTATATCACTTTTATTGATGTCATTAAAACATTCTGTACTTTAAGCATGAAAAGCAATATTTC
AAAGTATTTTTAAACTCAACAAATGTCATCAAATATGTTGAATTGATCTAGAAATTATTTCATATATAAATCAGAATTTTTTTGCATTTA
TGAACGGCTGTTTTTCTACTTTGTAATTGTGAGACATTTTCTTGGGGAGGGAAAATTGGAATGGTTCCCTTTTTTAGAAATTGAAGTGGT
CTTCATATGTCAACTACAGAAAAGGAAAAAAATAGAAATTGAAGGATTTTTATGAAATTATATTGCATTACTATTTGCAGTCAAACTTTG
ATCCTTGTTTTTGAAATCATTTGTCAATTCGGAATGAAAAATTATAATGTAATTTTACATTACATAAGTTCCTTTTACAATTAAAAAATA
GCACTTCTTCATCTTATGCCTGTTTGAGAAGATATTAAATTTTCACATTGTTGACAGTGAAATGCTATGTTGGTTTATAAGATTACAGAC
CATTTGTTTTCATGTGGATAATTTTAGTGCATTGCTCACCCGGTATGTTTTTTTTTTTTAACTTGAACATTTTGCTTGTTTTGTTTTTCT
TTTTTAATTAGATAATCACACGGAAAATTAAGCTGTTCATATCTTTAAATTAGGATTGCAAACCAAGGAAAGAACGCATTTGAGATTTTA
AGATGTCACTTATAAGGGGAGAAGTGTTCTTAAAAAGTCAACCAGAAAACTGTTATGCCTTTTATTTGTTTGCAAGGATGTCTTTGTAAT
GTGTTTCATGAATAGAATATCCAATAGAGATAAGCTGACTTGAATCATTTTGAGCAATTTTGCCCTGTGTTATATGTGTTTCACGCACAT
ATTTGCAGTTGGATTTTCTCCAACAGAAAGTGGATTCACTACTGGCACATTAACAAGCACCAATAGGTTTTTATTCCAACTCCGAGCACT
GTGGTTGAGTAACATCACCTCAATTTTTTATTATCCTTAAAGATATTGCATTTTCATATTCTTTATTTATAAAGGATCAATGCTGCTGTA
AATACAGGTATTTTTAATTTTAAAATTTCATTCCACCACCATCAGATGCAGTTCCCTATTTTGTTTAATGAAGGGATATATAAGCTTTCT
AATGGTGTCTTCAGAAATTTATAAAATGTAAATACTGATTTGACTGGTCTTTAAGATGTGTTTAACTGTGAGGCTATTTAACGAATAGTG
TGGATGTGATTTGTCATCCAGTATTAAGTTCTTAGTCATTGATTTTTGTGTTTAAAAAAAAATAGGAAAGAGGGAAACTGCAGCTTTCAT
TACAGATTCCTTGATTGGTAAGCTCTCCAAATGATGAGTTCTAGTAAACTCTGATTTTTGCCTCTGGATAGTAGATCTCGAGCGTTTATC
TCGGGCTTTAATTTGCTAAAGCTGTGCACATATGTAAAAAAAAAAAAAAAAAGATTATTTTAGGGGAGATGTAGGTGTAGAATTATTGCT
TATGTCATTTCTTAAGCAGTTATGCTCTTAATGCTTAAAAGAAGGCTAGCATTGTTTGCACAAAAAGTTGGTGATTCCCACCCCAAATAG
TAATAAAATTACTTCTGTTGAGTAAACTTTTTATGTCATCGTAAAAGCTGAAAAAATCCCTTTGTTTCTATTTATAAAAAAAGTGCTTTT
CTATATGTACCCTTGATAACAGATTTTGAAGAAATCCTGTAAGATGATAAAGCATTTGAATGGTACAGTAGATGTAAAAAAAATTCAGTT

>38417_38417_1_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000395418_SUZ12_chr17_30267305_ENST00000322652_length(amino acids)=629AA_BP=
MHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVS
CPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNRED
GEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATR
NSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLC
HSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSG
HNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKK

--------------------------------------------------------------
>38417_38417_2_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000395418_SUZ12_chr17_30267305_ENST00000580398_length(transcript)=3943nt_BP=420nt
GCCGTGGCAGGCTGGCTGGGTACCGGCTGTCGCTGACCCAGGAGAAGCTGCCTGTCTACATCAGCCTGGGCTGCAGCGCGCTGCCGCCGC
GGGGCCGGCAGCCATGGCCAAGGACATCCTGGGTGAAGCAGGGCTACACTTTGATGAACTGAACAAGCTGAGGGTGTTGGACCCAGAGGT
TACCCAGCAGACCATAGAGCTGAAGGAAGAGTGCAAAGACTTTGTGGACAAAATTGGCCAGTTTCAGAAAATAGTTGGTGGTTTAATTGA
GCTTGTTGATCAACTTGCAAAAGAAGCAGAAAATGAAAAGATGAAGGCCATCGGTGCTCGGAACTTGCTCAAATCTATAGCAAAGCAGAG
AGAAGCTCAACAGCAGCAACTTCAAGCCCTAATAGCAGAAAAGAAAATGCAGCTAGAAAGAGCCAACACAGATCTATAGATTTCTTCGAA
CTCGGAATCTCATAGCACCAATATTTTTGCACAGAACTCTTACTTACATGTCTCATCGAAACTCCAGAACAAACATCAAAAGCTTGTCAG
CTCATTTGCAGCTTACGTTTACTGGTTTCTTCCACAAAAATGATAAGCCATCACCAAACTCAGAAAATGAACAAAATTCTGTTACCCTGG
AAGTCCTGCTTGTGAAAGTTTGCCACAAAAAAAGAAAGGATGTAAGTTGTCCAATAAGGCAAGTTCCCACAGGTAAAAAGCAGGTGCCTT
TGAATCCTGACCTCAATCAAACAAAACCCGGAAATTTCCCGTCCCTTGCAGTTTCCAGTAATGAATTTGAACCTAGTAACAGCCATATGG
TGAAGTCTTACTCGTTGCTATTTAGAGTGACTCGTCCAGGAAGAAGAGAGTTTAATGGAATGATTAATGGAGAAACCAATGAAAATATTG
ATGTCAATGAAGAGCTTCCAGCCAGAAGAAAACGAAATCGTGAGGATGGGGAAAAGACATTTGTTGCACAAATGACAGTATTTGATAAAA
ACAGGCGCTTACAGCTTTTAGATGGGGAATATGAAGTAGCCATGCAGGAAATGGAAGAATGTCCAATAAGCAAGAAAAGAGCAACATGGG
AGACTATTCTTGATGGGAAGAGGCTGCCTCCATTCGAAACATTTTCTCAGGGACCTACGTTGCAGTTCACTCTTCGTTGGACAGGAGAGA
CCAATGATAAATCTACGGCTCCTATTGCCAAACCTCTTGCCACTAGAAATTCAGAGAGTCTCCATCAGGAAAACAAGCCTGGTTCAGTTA
AACCTACTCAAACTATTGCTGTTAAAGAATCATTGACTACAGATCTACAAACAAGAAAAGAAAAGGATACTCCAAATGAAAACCGACAAA
AATTAAGAATATTTTATCAGTTTCTCTATAACAACAATACAAGGCAACAAACTGAAGCAAGAGATGACCTGCATTGCCCTTGGTGTACTC
TGAACTGCCGCAAACTTTATAGTTTACTCAAGCATCTTAAACTCTGCCATAGCAGATTTATCTTCAACTATGTTTATCATCCAAAAGGTG
CTAGGATAGATGTTTCTATCAATGAGTGTTATGATGGCTCCTATGCAGGAAATCCTCAGGATATTCATCGCCAACCTGGATTTGCTTTTA
GTCGCAACGGACCAGTTAAGAGAACACCTATCACACATATTCTTGTGTGCAGGCCAAAACGAACAAAAGCAAGCATGTCTGAATTTCTTG
AATCTGAAGATGGGGAAGTAGAACAGCAAAGAACATATAGTAGTGGCCACAATCGTCTGTATTTCCATAGTGATACCTGCTTACCTCTCC
GTCCACAAGAAATGGAAGTAGATAGTGAAGATGAAAAGGATCCTGAATGGCTAAGAGAAAAAACCATTACACAAATTGAAGAGTTTTCTG
ATGTTAATGAAGGAGAGAAAGAAGTGATGAAACTCTGGAATCTCCATGTCATGAAGCATGGGTTTATTGCTGACAATCAAATGAATCATG
CCTGTATGCTGTTTGTAGAAAATTATGGACAGAAAATAATTAAGAAGAATTTATGTCGAAACTTCATGCTTCATCTAGTCAGCATGCATG
ACTTTAATCTTATTAGCATAATGTCAATAGATAAAGCTGTTACCAAGCTCCGTGAAATGCAGCAAAAATTAGAAAAGGGGGAATCTGCTT
CCCCTGCAAACGAAGAAATAACTGAAGAACAAAATGGGACAGCAAATGGATTTAGTGAAATTAACTCAAAAGAGAAAGCTTTGGAAACAG
ATAGTGTCTCAGGGGTTTCAAAACAGAGCAAAAAACAAAAACTCTGAAAAGCTCTAACCCCATGTTATGGACAAACACTGAAATTACATT
TTAGGGAATTCATCCTCTAAGAATTATGTTTTTGTTTTTAATCATATGTTCCAAACAGGCACTGTTAGATGAAGTAAATGATTTCAACAA
GGATATTTGTATCAGGGTTCTACTTCACTTCATTATGCAGCATTACATGTATATCACTTTTATTGATGTCATTAAAACATTCTGTACTTT
AAGCATGAAAAGCAATATTTCAAAGTATTTTTAAACTCAACAAATGTCATCAAATATGTTGAATTGATCTAGAAATTATTTCATATATAA
ATCAGAATTTTTTTGCATTTATGAACGGCTGTTTTTCTACTTTGTAATTGTGAGACATTTTCTTGGGGAGGGAAAATTGGAATGGTTCCC
TTTTTTAGAAATTGAAGTGGTCTTCATATGTCAACTACAGAAAAGGAAAAAAATAGAAATTGAAGGATTTTTATGAAATTATATTGCATT
ACTATTTGCAGTCAAACTTTGATCCTTGTTTTTGAAATCATTTGTCAATTCGGAATGAAAAATTATAATGTAATTTTACATTACATAAGT
TCCTTTTACAATTAAAAAATAGCACTTCTTCATCTTATGCCTGTTTGAGAAGATATTAAATTTTCACATTGTTGACAGTGAAATGCTATG
TTGGTTTATAAGATTACAGACCATTTGTTTTCATGTGGATAATTTTAGTGCATTGCTCACCCGGTATGTTTTTTTTTTTTAACTTGAACA
TTTTGCTTGTTTTGTTTTTCTTTTTTAATTAGATAATCACACGGAAAATTAAGCTGTTCATATCTTTAAATTAGGATTGCAAACCAAGGA
AAGAACGCATTTGAGATTTTAAGATGTCACTTATAAGGGGAGAAGTGTTCTTAAAAAGTCAACCAGAAAACTGTTATGCCTTTTATTTGT
TTGCAAGGATGTCTTTGTAATGTGTTTCATGAATAGAATATCCAATAGAGATAAGCTGACTTGAATCATTTTGAGCAATTTTGCCCTGTG
TTATATGTGTTTCACGCACATATTTGCAGTTGGATTTTCTCCAACAGAAAGTGGATTCACTACTGGCACATTAACAAGCACCAATAGGTT
TTTATTCCAACTCCGAGCACTGTGGTTGAGTAACATCACCTCAATTTTTTATTATCCTTAAAGATATTGCATTTTCATATTCTTTATTTA
TAAAGGATCAATGCTGCTGTAAATACAGGTATTTTTAATTTTAAAATTTCATTCCACCACCATCAGATGCAGTTCCCTATTTTGTTTAAT
GAAGGGATATATAAGCTTTCTAATGGTGTCTTCAGAAATTTATAAAATGTAAATACTGATTTGACTGGTCTTTAAGATGTGTTTAACTGT
GAGGCTATTTAACGAATAGTGTGGATGTGATTTGTCATCCAGTATTAAGTTCTTAGTCATTGATTTTTGTGTTTAAAAAAAAATAGGAAA
GAGGGAAACTGCAGCTTTCATTACAGATTCCTTGATTGGTAAGCTCTCCAAATGATGAGTTCTAGTAAACTCTGATTTTTGCCTCTGGAT

>38417_38417_2_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000395418_SUZ12_chr17_30267305_ENST00000580398_length(amino acids)=606AA_BP=
MHRTLTYMSHRNSRTNIKSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTK
PGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDG
EYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVK
ESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINE
CYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDS
EDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMS

--------------------------------------------------------------
>38417_38417_3_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000579419_SUZ12_chr17_30267305_ENST00000322652_length(transcript)=4443nt_BP=455nt
CCGTGGCAGGCTGGCTGGGTACCGGCTGTCGCTGACCCAGGAGAAGCTGCCTGTCTACATCAGCCTGGGCTGCAGCGCGCTGCCGCCGCG
GGGCCGGCAGAGCAGAACTCCTCTAGGGAACCTGGATGGGAAACAGCCATGGCCAAGGACATCCTGGGTGAAGCAGGGCTACACTTTGAT
GAACTGAACAAGCTGAGGGTGTTGGACCCAGAGGTTACCCAGCAGACCATAGAGCTGAAGGAAGAGTGCAAAGACTTTGTGGACAAAATT
GGCCAGTTTCAGAAAATAGTTGGTGGTTTAATTGAGCTTGTTGATCAACTTGCAAAAGAAGCAGAAAATGAAAAGATGAAGGCCATCGGT
GCTCGGAACTTGCTCAAATCTATAGCAAAGCAGAGAGAAGCTCAACAGCAGCAACTTCAAGCCCTAATAGCAGAAAAGAAAATGCAGCTA
GAAAGAGCCAACACAGATCTATAGATTTCTTCGAACTCGGAATCTCATAGCACCAATATTTTTGCACAGAACTCTTACTTACATGTCTCA
TCGAAACTCCAGAACAAACATCAAAAGGAAAACATTTAAAGTTGATGATATGTTATCAAAAGTAGAGAAAATGAAAGGAGAGCAAGAATC
TCATAGCTTGTCAGCTCATTTGCAGCTTACGTTTACTGGTTTCTTCCACAAAAATGATAAGCCATCACCAAACTCAGAAAATGAACAAAA
TTCTGTTACCCTGGAAGTCCTGCTTGTGAAAGTTTGCCACAAAAAAAGAAAGGATGTAAGTTGTCCAATAAGGCAAGTTCCCACAGGTAA
AAAGCAGGTGCCTTTGAATCCTGACCTCAATCAAACAAAACCCGGAAATTTCCCGTCCCTTGCAGTTTCCAGTAATGAATTTGAACCTAG
TAACAGCCATATGGTGAAGTCTTACTCGTTGCTATTTAGAGTGACTCGTCCAGGAAGAAGAGAGTTTAATGGAATGATTAATGGAGAAAC
CAATGAAAATATTGATGTCAATGAAGAGCTTCCAGCCAGAAGAAAACGAAATCGTGAGGATGGGGAAAAGACATTTGTTGCACAAATGAC
AGTATTTGATAAAAACAGGCGCTTACAGCTTTTAGATGGGGAATATGAAGTAGCCATGCAGGAAATGGAAGAATGTCCAATAAGCAAGAA
AAGAGCAACATGGGAGACTATTCTTGATGGGAAGAGGCTGCCTCCATTCGAAACATTTTCTCAGGGACCTACGTTGCAGTTCACTCTTCG
TTGGACAGGAGAGACCAATGATAAATCTACGGCTCCTATTGCCAAACCTCTTGCCACTAGAAATTCAGAGAGTCTCCATCAGGAAAACAA
GCCTGGTTCAGTTAAACCTACTCAAACTATTGCTGTTAAAGAATCATTGACTACAGATCTACAAACAAGAAAAGAAAAGGATACTCCAAA
TGAAAACCGACAAAAATTAAGAATATTTTATCAGTTTCTCTATAACAACAATACAAGGCAACAAACTGAAGCAAGAGATGACCTGCATTG
CCCTTGGTGTACTCTGAACTGCCGCAAACTTTATAGTTTACTCAAGCATCTTAAACTCTGCCATAGCAGATTTATCTTCAACTATGTTTA
TCATCCAAAAGGTGCTAGGATAGATGTTTCTATCAATGAGTGTTATGATGGCTCCTATGCAGGAAATCCTCAGGATATTCATCGCCAACC
TGGATTTGCTTTTAGTCGCAACGGACCAGTTAAGAGAACACCTATCACACATATTCTTGTGTGCAGGCCAAAACGAACAAAAGCAAGCAT
GTCTGAATTTCTTGAATCTGAAGATGGGGAAGTAGAACAGCAAAGAACATATAGTAGTGGCCACAATCGTCTGTATTTCCATAGTGATAC
CTGCTTACCTCTCCGTCCACAAGAAATGGAAGTAGATAGTGAAGATGAAAAGGATCCTGAATGGCTAAGAGAAAAAACCATTACACAAAT
TGAAGAGTTTTCTGATGTTAATGAAGGAGAGAAAGAAGTGATGAAACTCTGGAATCTCCATGTCATGAAGCATGGGTTTATTGCTGACAA
TCAAATGAATCATGCCTGTATGCTGTTTGTAGAAAATTATGGACAGAAAATAATTAAGAAGAATTTATGTCGAAACTTCATGCTTCATCT
AGTCAGCATGCATGACTTTAATCTTATTAGCATAATGTCAATAGATAAAGCTGTTACCAAGCTCCGTGAAATGCAGCAAAAATTAGAAAA
GGGGGAATCTGCTTCCCCTGCAAACGAAGAAATAACTGAAGAACAAAATGGGACAGCAAATGGATTTAGTGAAATTAACTCAAAAGAGAA
AGCTTTGGAAACAGATAGTGTCTCAGGGGTTTCAAAACAGAGCAAAAAACAAAAACTCTGAAAAGCTCTAACCCCATGTTATGGACAAAC
ACTGAAATTACATTTTAGGGAATTCATCCTCTAAGAATTATGTTTTTGTTTTTAATCATATGTTCCAAACAGGCACTGTTAGATGAAGTA
AATGATTTCAACAAGGATATTTGTATCAGGGTTCTACTTCACTTCATTATGCAGCATTACATGTATATCACTTTTATTGATGTCATTAAA
ACATTCTGTACTTTAAGCATGAAAAGCAATATTTCAAAGTATTTTTAAACTCAACAAATGTCATCAAATATGTTGAATTGATCTAGAAAT
TATTTCATATATAAATCAGAATTTTTTTGCATTTATGAACGGCTGTTTTTCTACTTTGTAATTGTGAGACATTTTCTTGGGGAGGGAAAA
TTGGAATGGTTCCCTTTTTTAGAAATTGAAGTGGTCTTCATATGTCAACTACAGAAAAGGAAAAAAATAGAAATTGAAGGATTTTTATGA
AATTATATTGCATTACTATTTGCAGTCAAACTTTGATCCTTGTTTTTGAAATCATTTGTCAATTCGGAATGAAAAATTATAATGTAATTT
TACATTACATAAGTTCCTTTTACAATTAAAAAATAGCACTTCTTCATCTTATGCCTGTTTGAGAAGATATTAAATTTTCACATTGTTGAC
AGTGAAATGCTATGTTGGTTTATAAGATTACAGACCATTTGTTTTCATGTGGATAATTTTAGTGCATTGCTCACCCGGTATGTTTTTTTT
TTTTAACTTGAACATTTTGCTTGTTTTGTTTTTCTTTTTTAATTAGATAATCACACGGAAAATTAAGCTGTTCATATCTTTAAATTAGGA
TTGCAAACCAAGGAAAGAACGCATTTGAGATTTTAAGATGTCACTTATAAGGGGAGAAGTGTTCTTAAAAAGTCAACCAGAAAACTGTTA
TGCCTTTTATTTGTTTGCAAGGATGTCTTTGTAATGTGTTTCATGAATAGAATATCCAATAGAGATAAGCTGACTTGAATCATTTTGAGC
AATTTTGCCCTGTGTTATATGTGTTTCACGCACATATTTGCAGTTGGATTTTCTCCAACAGAAAGTGGATTCACTACTGGCACATTAACA
AGCACCAATAGGTTTTTATTCCAACTCCGAGCACTGTGGTTGAGTAACATCACCTCAATTTTTTATTATCCTTAAAGATATTGCATTTTC
ATATTCTTTATTTATAAAGGATCAATGCTGCTGTAAATACAGGTATTTTTAATTTTAAAATTTCATTCCACCACCATCAGATGCAGTTCC
CTATTTTGTTTAATGAAGGGATATATAAGCTTTCTAATGGTGTCTTCAGAAATTTATAAAATGTAAATACTGATTTGACTGGTCTTTAAG
ATGTGTTTAACTGTGAGGCTATTTAACGAATAGTGTGGATGTGATTTGTCATCCAGTATTAAGTTCTTAGTCATTGATTTTTGTGTTTAA
AAAAAAATAGGAAAGAGGGAAACTGCAGCTTTCATTACAGATTCCTTGATTGGTAAGCTCTCCAAATGATGAGTTCTAGTAAACTCTGAT
TTTTGCCTCTGGATAGTAGATCTCGAGCGTTTATCTCGGGCTTTAATTTGCTAAAGCTGTGCACATATGTAAAAAAAAAAAAAAAAAGAT
TATTTTAGGGGAGATGTAGGTGTAGAATTATTGCTTATGTCATTTCTTAAGCAGTTATGCTCTTAATGCTTAAAAGAAGGCTAGCATTGT
TTGCACAAAAAGTTGGTGATTCCCACCCCAAATAGTAATAAAATTACTTCTGTTGAGTAAACTTTTTATGTCATCGTAAAAGCTGAAAAA
ATCCCTTTGTTTCTATTTATAAAAAAAGTGCTTTTCTATATGTACCCTTGATAACAGATTTTGAAGAAATCCTGTAAGATGATAAAGCAT
TTGAATGGTACAGTAGATGTAAAAAAAATTCAGTTTAAAAGAACATTTGTTTTTACATTAAATGTTTATTTGAAATCAAATGATTTTGTA

>38417_38417_3_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000579419_SUZ12_chr17_30267305_ENST00000322652_length(amino acids)=629AA_BP=
MHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVS
CPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNRED
GEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATR
NSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLC
HSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSG
HNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKK

--------------------------------------------------------------
>38417_38417_4_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000579419_SUZ12_chr17_30267305_ENST00000580398_length(transcript)=3978nt_BP=455nt
CCGTGGCAGGCTGGCTGGGTACCGGCTGTCGCTGACCCAGGAGAAGCTGCCTGTCTACATCAGCCTGGGCTGCAGCGCGCTGCCGCCGCG
GGGCCGGCAGAGCAGAACTCCTCTAGGGAACCTGGATGGGAAACAGCCATGGCCAAGGACATCCTGGGTGAAGCAGGGCTACACTTTGAT
GAACTGAACAAGCTGAGGGTGTTGGACCCAGAGGTTACCCAGCAGACCATAGAGCTGAAGGAAGAGTGCAAAGACTTTGTGGACAAAATT
GGCCAGTTTCAGAAAATAGTTGGTGGTTTAATTGAGCTTGTTGATCAACTTGCAAAAGAAGCAGAAAATGAAAAGATGAAGGCCATCGGT
GCTCGGAACTTGCTCAAATCTATAGCAAAGCAGAGAGAAGCTCAACAGCAGCAACTTCAAGCCCTAATAGCAGAAAAGAAAATGCAGCTA
GAAAGAGCCAACACAGATCTATAGATTTCTTCGAACTCGGAATCTCATAGCACCAATATTTTTGCACAGAACTCTTACTTACATGTCTCA
TCGAAACTCCAGAACAAACATCAAAAGCTTGTCAGCTCATTTGCAGCTTACGTTTACTGGTTTCTTCCACAAAAATGATAAGCCATCACC
AAACTCAGAAAATGAACAAAATTCTGTTACCCTGGAAGTCCTGCTTGTGAAAGTTTGCCACAAAAAAAGAAAGGATGTAAGTTGTCCAAT
AAGGCAAGTTCCCACAGGTAAAAAGCAGGTGCCTTTGAATCCTGACCTCAATCAAACAAAACCCGGAAATTTCCCGTCCCTTGCAGTTTC
CAGTAATGAATTTGAACCTAGTAACAGCCATATGGTGAAGTCTTACTCGTTGCTATTTAGAGTGACTCGTCCAGGAAGAAGAGAGTTTAA
TGGAATGATTAATGGAGAAACCAATGAAAATATTGATGTCAATGAAGAGCTTCCAGCCAGAAGAAAACGAAATCGTGAGGATGGGGAAAA
GACATTTGTTGCACAAATGACAGTATTTGATAAAAACAGGCGCTTACAGCTTTTAGATGGGGAATATGAAGTAGCCATGCAGGAAATGGA
AGAATGTCCAATAAGCAAGAAAAGAGCAACATGGGAGACTATTCTTGATGGGAAGAGGCTGCCTCCATTCGAAACATTTTCTCAGGGACC
TACGTTGCAGTTCACTCTTCGTTGGACAGGAGAGACCAATGATAAATCTACGGCTCCTATTGCCAAACCTCTTGCCACTAGAAATTCAGA
GAGTCTCCATCAGGAAAACAAGCCTGGTTCAGTTAAACCTACTCAAACTATTGCTGTTAAAGAATCATTGACTACAGATCTACAAACAAG
AAAAGAAAAGGATACTCCAAATGAAAACCGACAAAAATTAAGAATATTTTATCAGTTTCTCTATAACAACAATACAAGGCAACAAACTGA
AGCAAGAGATGACCTGCATTGCCCTTGGTGTACTCTGAACTGCCGCAAACTTTATAGTTTACTCAAGCATCTTAAACTCTGCCATAGCAG
ATTTATCTTCAACTATGTTTATCATCCAAAAGGTGCTAGGATAGATGTTTCTATCAATGAGTGTTATGATGGCTCCTATGCAGGAAATCC
TCAGGATATTCATCGCCAACCTGGATTTGCTTTTAGTCGCAACGGACCAGTTAAGAGAACACCTATCACACATATTCTTGTGTGCAGGCC
AAAACGAACAAAAGCAAGCATGTCTGAATTTCTTGAATCTGAAGATGGGGAAGTAGAACAGCAAAGAACATATAGTAGTGGCCACAATCG
TCTGTATTTCCATAGTGATACCTGCTTACCTCTCCGTCCACAAGAAATGGAAGTAGATAGTGAAGATGAAAAGGATCCTGAATGGCTAAG
AGAAAAAACCATTACACAAATTGAAGAGTTTTCTGATGTTAATGAAGGAGAGAAAGAAGTGATGAAACTCTGGAATCTCCATGTCATGAA
GCATGGGTTTATTGCTGACAATCAAATGAATCATGCCTGTATGCTGTTTGTAGAAAATTATGGACAGAAAATAATTAAGAAGAATTTATG
TCGAAACTTCATGCTTCATCTAGTCAGCATGCATGACTTTAATCTTATTAGCATAATGTCAATAGATAAAGCTGTTACCAAGCTCCGTGA
AATGCAGCAAAAATTAGAAAAGGGGGAATCTGCTTCCCCTGCAAACGAAGAAATAACTGAAGAACAAAATGGGACAGCAAATGGATTTAG
TGAAATTAACTCAAAAGAGAAAGCTTTGGAAACAGATAGTGTCTCAGGGGTTTCAAAACAGAGCAAAAAACAAAAACTCTGAAAAGCTCT
AACCCCATGTTATGGACAAACACTGAAATTACATTTTAGGGAATTCATCCTCTAAGAATTATGTTTTTGTTTTTAATCATATGTTCCAAA
CAGGCACTGTTAGATGAAGTAAATGATTTCAACAAGGATATTTGTATCAGGGTTCTACTTCACTTCATTATGCAGCATTACATGTATATC
ACTTTTATTGATGTCATTAAAACATTCTGTACTTTAAGCATGAAAAGCAATATTTCAAAGTATTTTTAAACTCAACAAATGTCATCAAAT
ATGTTGAATTGATCTAGAAATTATTTCATATATAAATCAGAATTTTTTTGCATTTATGAACGGCTGTTTTTCTACTTTGTAATTGTGAGA
CATTTTCTTGGGGAGGGAAAATTGGAATGGTTCCCTTTTTTAGAAATTGAAGTGGTCTTCATATGTCAACTACAGAAAAGGAAAAAAATA
GAAATTGAAGGATTTTTATGAAATTATATTGCATTACTATTTGCAGTCAAACTTTGATCCTTGTTTTTGAAATCATTTGTCAATTCGGAA
TGAAAAATTATAATGTAATTTTACATTACATAAGTTCCTTTTACAATTAAAAAATAGCACTTCTTCATCTTATGCCTGTTTGAGAAGATA
TTAAATTTTCACATTGTTGACAGTGAAATGCTATGTTGGTTTATAAGATTACAGACCATTTGTTTTCATGTGGATAATTTTAGTGCATTG
CTCACCCGGTATGTTTTTTTTTTTTAACTTGAACATTTTGCTTGTTTTGTTTTTCTTTTTTAATTAGATAATCACACGGAAAATTAAGCT
GTTCATATCTTTAAATTAGGATTGCAAACCAAGGAAAGAACGCATTTGAGATTTTAAGATGTCACTTATAAGGGGAGAAGTGTTCTTAAA
AAGTCAACCAGAAAACTGTTATGCCTTTTATTTGTTTGCAAGGATGTCTTTGTAATGTGTTTCATGAATAGAATATCCAATAGAGATAAG
CTGACTTGAATCATTTTGAGCAATTTTGCCCTGTGTTATATGTGTTTCACGCACATATTTGCAGTTGGATTTTCTCCAACAGAAAGTGGA
TTCACTACTGGCACATTAACAAGCACCAATAGGTTTTTATTCCAACTCCGAGCACTGTGGTTGAGTAACATCACCTCAATTTTTTATTAT
CCTTAAAGATATTGCATTTTCATATTCTTTATTTATAAAGGATCAATGCTGCTGTAAATACAGGTATTTTTAATTTTAAAATTTCATTCC
ACCACCATCAGATGCAGTTCCCTATTTTGTTTAATGAAGGGATATATAAGCTTTCTAATGGTGTCTTCAGAAATTTATAAAATGTAAATA
CTGATTTGACTGGTCTTTAAGATGTGTTTAACTGTGAGGCTATTTAACGAATAGTGTGGATGTGATTTGTCATCCAGTATTAAGTTCTTA
GTCATTGATTTTTGTGTTTAAAAAAAAATAGGAAAGAGGGAAACTGCAGCTTTCATTACAGATTCCTTGATTGGTAAGCTCTCCAAATGA
TGAGTTCTAGTAAACTCTGATTTTTGCCTCTGGATAGTAGATCTCGAGCGTTTATCTCGGGCTTTAATTTGCTAAAGCTGTGCACATATG

>38417_38417_4_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000579419_SUZ12_chr17_30267305_ENST00000580398_length(amino acids)=606AA_BP=
MHRTLTYMSHRNSRTNIKSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTK
PGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDG
EYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVK
ESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINE
CYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDS
EDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMS

--------------------------------------------------------------
>38417_38417_5_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000585313_SUZ12_chr17_30267305_ENST00000322652_length(transcript)=4443nt_BP=455nt
CCGTGGCAGGCTGGCTGGGTACCGGCTGTCGCTGACCCAGGAGAAGCTGCCTGTCTACATCAGCCTGGGCTGCAGCGCGCTGCCGCCGCG
GGGCCGGCAGAGCAGAACTCCTCTAGGGAACCTGGATGGGAAACAGCCATGGCCAAGGACATCCTGGGTGAAGCAGGGCTACACTTTGAT
GAACTGAACAAGCTGAGGGTGTTGGACCCAGAGGTTACCCAGCAGACCATAGAGCTGAAGGAAGAGTGCAAAGACTTTGTGGACAAAATT
GGCCAGTTTCAGAAAATAGTTGGTGGTTTAATTGAGCTTGTTGATCAACTTGCAAAAGAAGCAGAAAATGAAAAGATGAAGGCCATCGGT
GCTCGGAACTTGCTCAAATCTATAGCAAAGCAGAGAGAAGCTCAACAGCAGCAACTTCAAGCCCTAATAGCAGAAAAGAAAATGCAGCTA
GAAAGAGCCAACACAGATCTATAGATTTCTTCGAACTCGGAATCTCATAGCACCAATATTTTTGCACAGAACTCTTACTTACATGTCTCA
TCGAAACTCCAGAACAAACATCAAAAGGAAAACATTTAAAGTTGATGATATGTTATCAAAAGTAGAGAAAATGAAAGGAGAGCAAGAATC
TCATAGCTTGTCAGCTCATTTGCAGCTTACGTTTACTGGTTTCTTCCACAAAAATGATAAGCCATCACCAAACTCAGAAAATGAACAAAA
TTCTGTTACCCTGGAAGTCCTGCTTGTGAAAGTTTGCCACAAAAAAAGAAAGGATGTAAGTTGTCCAATAAGGCAAGTTCCCACAGGTAA
AAAGCAGGTGCCTTTGAATCCTGACCTCAATCAAACAAAACCCGGAAATTTCCCGTCCCTTGCAGTTTCCAGTAATGAATTTGAACCTAG
TAACAGCCATATGGTGAAGTCTTACTCGTTGCTATTTAGAGTGACTCGTCCAGGAAGAAGAGAGTTTAATGGAATGATTAATGGAGAAAC
CAATGAAAATATTGATGTCAATGAAGAGCTTCCAGCCAGAAGAAAACGAAATCGTGAGGATGGGGAAAAGACATTTGTTGCACAAATGAC
AGTATTTGATAAAAACAGGCGCTTACAGCTTTTAGATGGGGAATATGAAGTAGCCATGCAGGAAATGGAAGAATGTCCAATAAGCAAGAA
AAGAGCAACATGGGAGACTATTCTTGATGGGAAGAGGCTGCCTCCATTCGAAACATTTTCTCAGGGACCTACGTTGCAGTTCACTCTTCG
TTGGACAGGAGAGACCAATGATAAATCTACGGCTCCTATTGCCAAACCTCTTGCCACTAGAAATTCAGAGAGTCTCCATCAGGAAAACAA
GCCTGGTTCAGTTAAACCTACTCAAACTATTGCTGTTAAAGAATCATTGACTACAGATCTACAAACAAGAAAAGAAAAGGATACTCCAAA
TGAAAACCGACAAAAATTAAGAATATTTTATCAGTTTCTCTATAACAACAATACAAGGCAACAAACTGAAGCAAGAGATGACCTGCATTG
CCCTTGGTGTACTCTGAACTGCCGCAAACTTTATAGTTTACTCAAGCATCTTAAACTCTGCCATAGCAGATTTATCTTCAACTATGTTTA
TCATCCAAAAGGTGCTAGGATAGATGTTTCTATCAATGAGTGTTATGATGGCTCCTATGCAGGAAATCCTCAGGATATTCATCGCCAACC
TGGATTTGCTTTTAGTCGCAACGGACCAGTTAAGAGAACACCTATCACACATATTCTTGTGTGCAGGCCAAAACGAACAAAAGCAAGCAT
GTCTGAATTTCTTGAATCTGAAGATGGGGAAGTAGAACAGCAAAGAACATATAGTAGTGGCCACAATCGTCTGTATTTCCATAGTGATAC
CTGCTTACCTCTCCGTCCACAAGAAATGGAAGTAGATAGTGAAGATGAAAAGGATCCTGAATGGCTAAGAGAAAAAACCATTACACAAAT
TGAAGAGTTTTCTGATGTTAATGAAGGAGAGAAAGAAGTGATGAAACTCTGGAATCTCCATGTCATGAAGCATGGGTTTATTGCTGACAA
TCAAATGAATCATGCCTGTATGCTGTTTGTAGAAAATTATGGACAGAAAATAATTAAGAAGAATTTATGTCGAAACTTCATGCTTCATCT
AGTCAGCATGCATGACTTTAATCTTATTAGCATAATGTCAATAGATAAAGCTGTTACCAAGCTCCGTGAAATGCAGCAAAAATTAGAAAA
GGGGGAATCTGCTTCCCCTGCAAACGAAGAAATAACTGAAGAACAAAATGGGACAGCAAATGGATTTAGTGAAATTAACTCAAAAGAGAA
AGCTTTGGAAACAGATAGTGTCTCAGGGGTTTCAAAACAGAGCAAAAAACAAAAACTCTGAAAAGCTCTAACCCCATGTTATGGACAAAC
ACTGAAATTACATTTTAGGGAATTCATCCTCTAAGAATTATGTTTTTGTTTTTAATCATATGTTCCAAACAGGCACTGTTAGATGAAGTA
AATGATTTCAACAAGGATATTTGTATCAGGGTTCTACTTCACTTCATTATGCAGCATTACATGTATATCACTTTTATTGATGTCATTAAA
ACATTCTGTACTTTAAGCATGAAAAGCAATATTTCAAAGTATTTTTAAACTCAACAAATGTCATCAAATATGTTGAATTGATCTAGAAAT
TATTTCATATATAAATCAGAATTTTTTTGCATTTATGAACGGCTGTTTTTCTACTTTGTAATTGTGAGACATTTTCTTGGGGAGGGAAAA
TTGGAATGGTTCCCTTTTTTAGAAATTGAAGTGGTCTTCATATGTCAACTACAGAAAAGGAAAAAAATAGAAATTGAAGGATTTTTATGA
AATTATATTGCATTACTATTTGCAGTCAAACTTTGATCCTTGTTTTTGAAATCATTTGTCAATTCGGAATGAAAAATTATAATGTAATTT
TACATTACATAAGTTCCTTTTACAATTAAAAAATAGCACTTCTTCATCTTATGCCTGTTTGAGAAGATATTAAATTTTCACATTGTTGAC
AGTGAAATGCTATGTTGGTTTATAAGATTACAGACCATTTGTTTTCATGTGGATAATTTTAGTGCATTGCTCACCCGGTATGTTTTTTTT
TTTTAACTTGAACATTTTGCTTGTTTTGTTTTTCTTTTTTAATTAGATAATCACACGGAAAATTAAGCTGTTCATATCTTTAAATTAGGA
TTGCAAACCAAGGAAAGAACGCATTTGAGATTTTAAGATGTCACTTATAAGGGGAGAAGTGTTCTTAAAAAGTCAACCAGAAAACTGTTA
TGCCTTTTATTTGTTTGCAAGGATGTCTTTGTAATGTGTTTCATGAATAGAATATCCAATAGAGATAAGCTGACTTGAATCATTTTGAGC
AATTTTGCCCTGTGTTATATGTGTTTCACGCACATATTTGCAGTTGGATTTTCTCCAACAGAAAGTGGATTCACTACTGGCACATTAACA
AGCACCAATAGGTTTTTATTCCAACTCCGAGCACTGTGGTTGAGTAACATCACCTCAATTTTTTATTATCCTTAAAGATATTGCATTTTC
ATATTCTTTATTTATAAAGGATCAATGCTGCTGTAAATACAGGTATTTTTAATTTTAAAATTTCATTCCACCACCATCAGATGCAGTTCC
CTATTTTGTTTAATGAAGGGATATATAAGCTTTCTAATGGTGTCTTCAGAAATTTATAAAATGTAAATACTGATTTGACTGGTCTTTAAG
ATGTGTTTAACTGTGAGGCTATTTAACGAATAGTGTGGATGTGATTTGTCATCCAGTATTAAGTTCTTAGTCATTGATTTTTGTGTTTAA
AAAAAAATAGGAAAGAGGGAAACTGCAGCTTTCATTACAGATTCCTTGATTGGTAAGCTCTCCAAATGATGAGTTCTAGTAAACTCTGAT
TTTTGCCTCTGGATAGTAGATCTCGAGCGTTTATCTCGGGCTTTAATTTGCTAAAGCTGTGCACATATGTAAAAAAAAAAAAAAAAAGAT
TATTTTAGGGGAGATGTAGGTGTAGAATTATTGCTTATGTCATTTCTTAAGCAGTTATGCTCTTAATGCTTAAAAGAAGGCTAGCATTGT
TTGCACAAAAAGTTGGTGATTCCCACCCCAAATAGTAATAAAATTACTTCTGTTGAGTAAACTTTTTATGTCATCGTAAAAGCTGAAAAA
ATCCCTTTGTTTCTATTTATAAAAAAAGTGCTTTTCTATATGTACCCTTGATAACAGATTTTGAAGAAATCCTGTAAGATGATAAAGCAT
TTGAATGGTACAGTAGATGTAAAAAAAATTCAGTTTAAAAGAACATTTGTTTTTACATTAAATGTTTATTTGAAATCAAATGATTTTGTA

>38417_38417_5_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000585313_SUZ12_chr17_30267305_ENST00000322652_length(amino acids)=629AA_BP=
MHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVS
CPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNRED
GEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATR
NSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLC
HSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSG
HNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKK

--------------------------------------------------------------
>38417_38417_6_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000585313_SUZ12_chr17_30267305_ENST00000580398_length(transcript)=3978nt_BP=455nt
CCGTGGCAGGCTGGCTGGGTACCGGCTGTCGCTGACCCAGGAGAAGCTGCCTGTCTACATCAGCCTGGGCTGCAGCGCGCTGCCGCCGCG
GGGCCGGCAGAGCAGAACTCCTCTAGGGAACCTGGATGGGAAACAGCCATGGCCAAGGACATCCTGGGTGAAGCAGGGCTACACTTTGAT
GAACTGAACAAGCTGAGGGTGTTGGACCCAGAGGTTACCCAGCAGACCATAGAGCTGAAGGAAGAGTGCAAAGACTTTGTGGACAAAATT
GGCCAGTTTCAGAAAATAGTTGGTGGTTTAATTGAGCTTGTTGATCAACTTGCAAAAGAAGCAGAAAATGAAAAGATGAAGGCCATCGGT
GCTCGGAACTTGCTCAAATCTATAGCAAAGCAGAGAGAAGCTCAACAGCAGCAACTTCAAGCCCTAATAGCAGAAAAGAAAATGCAGCTA
GAAAGAGCCAACACAGATCTATAGATTTCTTCGAACTCGGAATCTCATAGCACCAATATTTTTGCACAGAACTCTTACTTACATGTCTCA
TCGAAACTCCAGAACAAACATCAAAAGCTTGTCAGCTCATTTGCAGCTTACGTTTACTGGTTTCTTCCACAAAAATGATAAGCCATCACC
AAACTCAGAAAATGAACAAAATTCTGTTACCCTGGAAGTCCTGCTTGTGAAAGTTTGCCACAAAAAAAGAAAGGATGTAAGTTGTCCAAT
AAGGCAAGTTCCCACAGGTAAAAAGCAGGTGCCTTTGAATCCTGACCTCAATCAAACAAAACCCGGAAATTTCCCGTCCCTTGCAGTTTC
CAGTAATGAATTTGAACCTAGTAACAGCCATATGGTGAAGTCTTACTCGTTGCTATTTAGAGTGACTCGTCCAGGAAGAAGAGAGTTTAA
TGGAATGATTAATGGAGAAACCAATGAAAATATTGATGTCAATGAAGAGCTTCCAGCCAGAAGAAAACGAAATCGTGAGGATGGGGAAAA
GACATTTGTTGCACAAATGACAGTATTTGATAAAAACAGGCGCTTACAGCTTTTAGATGGGGAATATGAAGTAGCCATGCAGGAAATGGA
AGAATGTCCAATAAGCAAGAAAAGAGCAACATGGGAGACTATTCTTGATGGGAAGAGGCTGCCTCCATTCGAAACATTTTCTCAGGGACC
TACGTTGCAGTTCACTCTTCGTTGGACAGGAGAGACCAATGATAAATCTACGGCTCCTATTGCCAAACCTCTTGCCACTAGAAATTCAGA
GAGTCTCCATCAGGAAAACAAGCCTGGTTCAGTTAAACCTACTCAAACTATTGCTGTTAAAGAATCATTGACTACAGATCTACAAACAAG
AAAAGAAAAGGATACTCCAAATGAAAACCGACAAAAATTAAGAATATTTTATCAGTTTCTCTATAACAACAATACAAGGCAACAAACTGA
AGCAAGAGATGACCTGCATTGCCCTTGGTGTACTCTGAACTGCCGCAAACTTTATAGTTTACTCAAGCATCTTAAACTCTGCCATAGCAG
ATTTATCTTCAACTATGTTTATCATCCAAAAGGTGCTAGGATAGATGTTTCTATCAATGAGTGTTATGATGGCTCCTATGCAGGAAATCC
TCAGGATATTCATCGCCAACCTGGATTTGCTTTTAGTCGCAACGGACCAGTTAAGAGAACACCTATCACACATATTCTTGTGTGCAGGCC
AAAACGAACAAAAGCAAGCATGTCTGAATTTCTTGAATCTGAAGATGGGGAAGTAGAACAGCAAAGAACATATAGTAGTGGCCACAATCG
TCTGTATTTCCATAGTGATACCTGCTTACCTCTCCGTCCACAAGAAATGGAAGTAGATAGTGAAGATGAAAAGGATCCTGAATGGCTAAG
AGAAAAAACCATTACACAAATTGAAGAGTTTTCTGATGTTAATGAAGGAGAGAAAGAAGTGATGAAACTCTGGAATCTCCATGTCATGAA
GCATGGGTTTATTGCTGACAATCAAATGAATCATGCCTGTATGCTGTTTGTAGAAAATTATGGACAGAAAATAATTAAGAAGAATTTATG
TCGAAACTTCATGCTTCATCTAGTCAGCATGCATGACTTTAATCTTATTAGCATAATGTCAATAGATAAAGCTGTTACCAAGCTCCGTGA
AATGCAGCAAAAATTAGAAAAGGGGGAATCTGCTTCCCCTGCAAACGAAGAAATAACTGAAGAACAAAATGGGACAGCAAATGGATTTAG
TGAAATTAACTCAAAAGAGAAAGCTTTGGAAACAGATAGTGTCTCAGGGGTTTCAAAACAGAGCAAAAAACAAAAACTCTGAAAAGCTCT
AACCCCATGTTATGGACAAACACTGAAATTACATTTTAGGGAATTCATCCTCTAAGAATTATGTTTTTGTTTTTAATCATATGTTCCAAA
CAGGCACTGTTAGATGAAGTAAATGATTTCAACAAGGATATTTGTATCAGGGTTCTACTTCACTTCATTATGCAGCATTACATGTATATC
ACTTTTATTGATGTCATTAAAACATTCTGTACTTTAAGCATGAAAAGCAATATTTCAAAGTATTTTTAAACTCAACAAATGTCATCAAAT
ATGTTGAATTGATCTAGAAATTATTTCATATATAAATCAGAATTTTTTTGCATTTATGAACGGCTGTTTTTCTACTTTGTAATTGTGAGA
CATTTTCTTGGGGAGGGAAAATTGGAATGGTTCCCTTTTTTAGAAATTGAAGTGGTCTTCATATGTCAACTACAGAAAAGGAAAAAAATA
GAAATTGAAGGATTTTTATGAAATTATATTGCATTACTATTTGCAGTCAAACTTTGATCCTTGTTTTTGAAATCATTTGTCAATTCGGAA
TGAAAAATTATAATGTAATTTTACATTACATAAGTTCCTTTTACAATTAAAAAATAGCACTTCTTCATCTTATGCCTGTTTGAGAAGATA
TTAAATTTTCACATTGTTGACAGTGAAATGCTATGTTGGTTTATAAGATTACAGACCATTTGTTTTCATGTGGATAATTTTAGTGCATTG
CTCACCCGGTATGTTTTTTTTTTTTAACTTGAACATTTTGCTTGTTTTGTTTTTCTTTTTTAATTAGATAATCACACGGAAAATTAAGCT
GTTCATATCTTTAAATTAGGATTGCAAACCAAGGAAAGAACGCATTTGAGATTTTAAGATGTCACTTATAAGGGGAGAAGTGTTCTTAAA
AAGTCAACCAGAAAACTGTTATGCCTTTTATTTGTTTGCAAGGATGTCTTTGTAATGTGTTTCATGAATAGAATATCCAATAGAGATAAG
CTGACTTGAATCATTTTGAGCAATTTTGCCCTGTGTTATATGTGTTTCACGCACATATTTGCAGTTGGATTTTCTCCAACAGAAAGTGGA
TTCACTACTGGCACATTAACAAGCACCAATAGGTTTTTATTCCAACTCCGAGCACTGTGGTTGAGTAACATCACCTCAATTTTTTATTAT
CCTTAAAGATATTGCATTTTCATATTCTTTATTTATAAAGGATCAATGCTGCTGTAAATACAGGTATTTTTAATTTTAAAATTTCATTCC
ACCACCATCAGATGCAGTTCCCTATTTTGTTTAATGAAGGGATATATAAGCTTTCTAATGGTGTCTTCAGAAATTTATAAAATGTAAATA
CTGATTTGACTGGTCTTTAAGATGTGTTTAACTGTGAGGCTATTTAACGAATAGTGTGGATGTGATTTGTCATCCAGTATTAAGTTCTTA
GTCATTGATTTTTGTGTTTAAAAAAAAATAGGAAAGAGGGAAACTGCAGCTTTCATTACAGATTCCTTGATTGGTAAGCTCTCCAAATGA
TGAGTTCTAGTAAACTCTGATTTTTGCCTCTGGATAGTAGATCTCGAGCGTTTATCTCGGGCTTTAATTTGCTAAAGCTGTGCACATATG

>38417_38417_6_IFT20-SUZ12_IFT20_chr17_26656199_ENST00000585313_SUZ12_chr17_30267305_ENST00000580398_length(amino acids)=606AA_BP=
MHRTLTYMSHRNSRTNIKSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTK
PGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDG
EYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVK
ESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINE
CYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDS
EDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for IFT20-SUZ12


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneSUZ12chr17:26656199chr17:30267305ENST00000322652016146_36391.33333333333333740.0AEBP2 and PHF19


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneSUZ12chr17:26656199chr17:30267305ENST0000032265201679_10691.33333333333333740.0JARID2 and EPOP


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for IFT20-SUZ12


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for IFT20-SUZ12


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource