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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:IFT74-CAAP1 (FusionGDB2 ID:38440)

Fusion Gene Summary for IFT74-CAAP1

check button Fusion gene summary
Fusion gene informationFusion gene name: IFT74-CAAP1
Fusion gene ID: 38440
HgeneTgene
Gene symbol

IFT74

CAAP1

Gene ID

80173

79886

Gene nameintraflagellar transport 74caspase activity and apoptosis inhibitor 1
SynonymsCCDC2|CMG-1|CMG1C9orf82|CAAP
Cytomap

9p21.2

9p21.2

Type of geneprotein-codingprotein-coding
Descriptionintraflagellar transport protein 74 homologcapillary morphogenesis gene 1 proteincapillary morphogenesis protein 1coiled-coil domain containing 2coiled-coil domain-containing protein 2intraflagellar transport 74 homologcaspase activity and apoptosis inhibitor 1conserved anti-apoptotic protein
Modification date2020032620200313
UniProtAcc

Q96LB3

Q9H8G2

Ensembl transtripts involved in fusion geneENST00000380062, ENST00000429045, 
ENST00000433700, ENST00000443698, 
ENST00000495958, ENST00000520187, 
ENST00000333916, ENST00000535437, 
Fusion gene scores* DoF score5 X 2 X 5=503 X 2 X 3=18
# samples 54
** MAII scorelog2(5/50*10)=0log2(4/18*10)=1.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: IFT74 [Title/Abstract] AND CAAP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointIFT74(26990193)-CAAP1(26861137), # samples:1
CAAP1(26884808)-IFT74(27009018), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across IFT74 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CAAP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerTCGA-CV-7101-11AIFT74chr9

26990193

+CAAP1chr9

26861137

-


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Fusion Gene ORF analysis for IFT74-CAAP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000380062ENST00000495958IFT74chr9

26990193

+CAAP1chr9

26861137

-
5CDS-5UTRENST00000429045ENST00000495958IFT74chr9

26990193

+CAAP1chr9

26861137

-
5CDS-5UTRENST00000433700ENST00000495958IFT74chr9

26990193

+CAAP1chr9

26861137

-
5CDS-5UTRENST00000443698ENST00000495958IFT74chr9

26990193

+CAAP1chr9

26861137

-
5CDS-intronENST00000380062ENST00000520187IFT74chr9

26990193

+CAAP1chr9

26861137

-
5CDS-intronENST00000429045ENST00000520187IFT74chr9

26990193

+CAAP1chr9

26861137

-
5CDS-intronENST00000433700ENST00000520187IFT74chr9

26990193

+CAAP1chr9

26861137

-
5CDS-intronENST00000443698ENST00000520187IFT74chr9

26990193

+CAAP1chr9

26861137

-
In-frameENST00000380062ENST00000333916IFT74chr9

26990193

+CAAP1chr9

26861137

-
In-frameENST00000380062ENST00000535437IFT74chr9

26990193

+CAAP1chr9

26861137

-
In-frameENST00000429045ENST00000333916IFT74chr9

26990193

+CAAP1chr9

26861137

-
In-frameENST00000429045ENST00000535437IFT74chr9

26990193

+CAAP1chr9

26861137

-
In-frameENST00000433700ENST00000333916IFT74chr9

26990193

+CAAP1chr9

26861137

-
In-frameENST00000433700ENST00000535437IFT74chr9

26990193

+CAAP1chr9

26861137

-
In-frameENST00000443698ENST00000333916IFT74chr9

26990193

+CAAP1chr9

26861137

-
In-frameENST00000443698ENST00000535437IFT74chr9

26990193

+CAAP1chr9

26861137

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000433700IFT74chr926990193+ENST00000333916CAAP1chr926861137-27517141271134335
ENST00000433700IFT74chr926990193+ENST00000535437CAAP1chr926861137-17007141271134335
ENST00000443698IFT74chr926990193+ENST00000333916CAAP1chr926861137-27957581711178335
ENST00000443698IFT74chr926990193+ENST00000535437CAAP1chr926861137-17447581711178335
ENST00000380062IFT74chr926990193+ENST00000333916CAAP1chr926861137-27877501631170335
ENST00000380062IFT74chr926990193+ENST00000535437CAAP1chr926861137-17367501631170335
ENST00000429045IFT74chr926990193+ENST00000333916CAAP1chr926861137-2681644571064335
ENST00000429045IFT74chr926990193+ENST00000535437CAAP1chr926861137-1630644571064335

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000433700ENST00000333916IFT74chr926990193+CAAP1chr926861137-9.95E-050.99990046
ENST00000433700ENST00000535437IFT74chr926990193+CAAP1chr926861137-0.0001971990.99980277
ENST00000443698ENST00000333916IFT74chr926990193+CAAP1chr926861137-0.0001108720.99988914
ENST00000443698ENST00000535437IFT74chr926990193+CAAP1chr926861137-0.0002412990.99975866
ENST00000380062ENST00000333916IFT74chr926990193+CAAP1chr926861137-0.0001058660.99989414
ENST00000380062ENST00000535437IFT74chr926990193+CAAP1chr926861137-0.0002278210.99977213
ENST00000429045ENST00000333916IFT74chr926990193+CAAP1chr926861137-0.0001031330.9998969
ENST00000429045ENST00000535437IFT74chr926990193+CAAP1chr926861137-0.0001878140.9998122

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Fusion Genomic Features for IFT74-CAAP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for IFT74-CAAP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:26990193/chr9:26861137)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
IFT74

Q96LB3

CAAP1

Q9H8G2

FUNCTION: Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis. {ECO:0000269|PubMed:23990561}.FUNCTION: Anti-apoptotic protein that modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop. {ECO:0000269|PubMed:21980415}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIFT74chr9:26990193chr9:26861137ENST00000380062+8201_90195601.0RegionNote=Basic region
HgeneIFT74chr9:26990193chr9:26861137ENST00000429045+8141_90195373.0RegionNote=Basic region
HgeneIFT74chr9:26990193chr9:26861137ENST00000433700+8201_90195601.0RegionNote=Basic region
HgeneIFT74chr9:26990193chr9:26861137ENST00000443698+8201_90195601.0RegionNote=Basic region
TgeneCAAP1chr9:26990193chr9:26861137ENST0000033391636281_311221362.0Coiled coilOntology_term=ECO:0000255
TgeneCAAP1chr9:26990193chr9:26861137ENST0000053543736281_31176217.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIFT74chr9:26990193chr9:26861137ENST00000380062+82098_482195601.0Coiled coilOntology_term=ECO:0000255
HgeneIFT74chr9:26990193chr9:26861137ENST00000429045+81498_482195373.0Coiled coilOntology_term=ECO:0000255
HgeneIFT74chr9:26990193chr9:26861137ENST00000433700+82098_482195601.0Coiled coilOntology_term=ECO:0000255
HgeneIFT74chr9:26990193chr9:26861137ENST00000443698+82098_482195601.0Coiled coilOntology_term=ECO:0000255
TgeneCAAP1chr9:26990193chr9:26861137ENST000003339163619_25221362.0Compositional biasNote=Poly-Ala
TgeneCAAP1chr9:26990193chr9:26861137ENST000005354373619_2576217.0Compositional biasNote=Poly-Ala


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Fusion Gene Sequence for IFT74-CAAP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>38440_38440_1_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000380062_CAAP1_chr9_26861137_ENST00000333916_length(transcript)=2787nt_BP=750nt
ATCCCGCCCCCGTTGCCGGGATACGCCGCGGCGCACGGCAGTTAGTGGGTAGGCCTGAGAGCCGAGGAAAACTGAGCGTGGGCCTCAGAA
AGAAGTTAAGGCACCCGCGAGCCGGGCAACTGCCCTCCTTCCGCGCCGGCGGAGCGATTAAAGTGAAGAAACAATGGCCAGCAATCACAA
ATCTTCAGCAGCTCGCCCTGTTTCAAGAGGTGGAGTTGGGTTAACAGGAAGGCCTCCTTCTGGGATACGACCCCTATCAGGAAATATTCG
AGTGGCAACTGCAATGCCACCTGGGACAGCAAGACCAGGTTCTCGTGGTTGTCCCATAGGGACTGGTGGAGTTCTGTCTTCTCAAATCAA
AGTTGCCCATCGCCCTGTAACACAACAAGGTTTGACTGGAATGAAAACTGGGACGAAAGGTCCCCAGAGGCAAATTTTAGACAAATCTTA
CTATCTTGGGCTTCTTAGAAGTAAAATAAGTGAACTTACAACTGAAGTTAATAAACTTCAGAAGGGAATAGAAATGTACAATCAAGAGAA
TTCAGTATATTTGTCATATGAAAAGAGGGCTGAGACTTTAGCTGTTGAGATAAAAGAGCTTCAAGGACAACTAGCAGACTACAACATGTT
GGTAGATAAACTTAATACCAACACTGAAATGGAAGAAGTAATGAATGATTACAATATGCTTAAAGCTCAAAATGATCGAGAAACACAAAG
TTTGGATGTCATATTTACTGAAAGACAAGCGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAGGTTT
GGAATTAAAACAAGGAAAAGGGGAAGATAGTGATGTACTCAGTATAAATGCAGATGCTTATGACAGCGACATAGAAGGCCCATGCAACGA
AGAAGCAGCTGCTCCCGAGGCACCAGAAAATACAGTCCAAAGTGAAGCTGGTCAGATAGATGACCTGGAGAAAGACATTGAGAAAAGTGT
GAATGAGATTCTAGGACTGGCAGAGTCTAGCCCAAACGAACCCAAAGCAGCCACCCTGGCTGTTCCTCCACCAGAAGATGTTCAACCTTC
TGCACAGCAACTGGAGCTGCTAGAACTTGAGATGAGGGCAAGAGCGATTAAAGCCCTAATGAAAGCTGGTGATATAAAAAAGCCAGCCTA
GGTATTTAACTTGATTTTGAATTTTAGGTATGTTTGAACAAAGCCACATCATTTAATTTTGTATCTAAAATTTATTTGGGGTCTTATATG
TTATTTCTCATGTAACCCTTATTAGGACTCATTTTAGCCCTAAATTACCTGTGGCTGTTTCTTTTTATTTTTTTGACTACTTTTATATTA
TAAATGTGTGTTACTGTCTTATGAATTCATGGCAATATAGTTGGATAGCCTGGATACTTTGTTAGATGAGTATTTAGCTGTGTCTGCAAA
TCTTAAAAGCCATTAGCAAAGAGTCGTGGTATTTTTTTCTTTATTTTTAAATGTTTGGGCACCAAACCTAAAAGCAAAAGATTGACGAAG
CATGTTTCTCTTAAGGCTACTTGTATTTTACAATACAATATTAAATTATTTAATTTGAGAAATTTAGTTTTGCTTATATGCACTTTTTAA
ATATATACTATTTTGAAGATTCCTTATGTAAATGCAAATTTCCTAGTTAAAACCGAATAACAGAGATCTGAAATGACTGAGAAAAACTTT
TTTATTAAAGGAAGGAATTAATTTAAGGCAATTTTTAACTATGTAGAACTAATTGCCCATGTTTAATTATAGCAGACACGCCATTCTAAC
AGGTATTTGATACCATTGGATGCATTATTCTAGGTTTTTTCTTTAATAAAAATGGAACAAGTTTTCATTTACATTCCAAGCTGTCAGGAA
ATGAAGAATATTTTATTATCTAGGATTTTATCTGATGTAGTTGCTTAAAGATCTGATGTGCTATAATTCCATGAATCAGAAATAATAAAA
TGCTATCATTCTGGATCTGAAGACTTTTGATACTTTTTCAAAAGCAAAATTAATTTCAGGAACCTTTGATAAGTTGTTGTTATAATTAAT
CTAATTTTGTATAGTTTTTGTAAATAAATTACCATCCTTCCACAATTAGGGATGCTTTTATCCCCCCATCACTAATTGCAGTTGTTTGAT
ACCAAAATAAATTTACGTAGAGATCCTTAACTTAAAATAAATTAATTTTTTCAAAAAACATAAATCTGGAACTGTTGTTTCTATATTTGA
TAACAAATACAGTATATTTTATTTATAAGCCATGGTCTACTGATACTGTATGAGGACTTTCCTTATATATAAAAGTTGCAGGGATTGTGT
TTTATTAGCTGCTTTAATTATGTTAATTTTAGAGAGTTTTTAAATGGAAATAGAGGACATTTATGAAACGCTGGAATTGCAGTTACAAAT
TCTTTTTGTTGTTGTTGTTCCTGAACATGCCTTGGAATAATTCTACCATTTTTTCCCCCTCCATAAATCTTTCTAATAAAGCATAGAAAA
AGCCTATATGATTTTAAATGCTTCTCTTAAGCTGGTAAACAGATTTGAGTTATGAGTTCATTGTTATTGCTTCAAGATGAAAAGACAGTG
ATATAATTTTTCTATTTCAACTTAAAAGTAATAGTTAATATGCTAAAGTAGTACAGAATAAACTTTATTGCTGCTTACTAACTACAAAAT

>38440_38440_1_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000380062_CAAP1_chr9_26861137_ENST00000333916_length(amino acids)=335AA_BP=196
MASNHKSSAARPVSRGGVGLTGRPPSGIRPLSGNIRVATAMPPGTARPGSRGCPIGTGGVLSSQIKVAHRPVTQQGLTGMKTGTKGPQRQ
ILDKSYYLGLLRSKISELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVEIKELQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQN
DRETQSLDVIFTERQAQDICIDSASSVRENKQPEGLELKQGKGEDSDVLSINADAYDSDIEGPCNEEAAAPEAPENTVQSEAGQIDDLEK

--------------------------------------------------------------
>38440_38440_2_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000380062_CAAP1_chr9_26861137_ENST00000535437_length(transcript)=1736nt_BP=750nt
ATCCCGCCCCCGTTGCCGGGATACGCCGCGGCGCACGGCAGTTAGTGGGTAGGCCTGAGAGCCGAGGAAAACTGAGCGTGGGCCTCAGAA
AGAAGTTAAGGCACCCGCGAGCCGGGCAACTGCCCTCCTTCCGCGCCGGCGGAGCGATTAAAGTGAAGAAACAATGGCCAGCAATCACAA
ATCTTCAGCAGCTCGCCCTGTTTCAAGAGGTGGAGTTGGGTTAACAGGAAGGCCTCCTTCTGGGATACGACCCCTATCAGGAAATATTCG
AGTGGCAACTGCAATGCCACCTGGGACAGCAAGACCAGGTTCTCGTGGTTGTCCCATAGGGACTGGTGGAGTTCTGTCTTCTCAAATCAA
AGTTGCCCATCGCCCTGTAACACAACAAGGTTTGACTGGAATGAAAACTGGGACGAAAGGTCCCCAGAGGCAAATTTTAGACAAATCTTA
CTATCTTGGGCTTCTTAGAAGTAAAATAAGTGAACTTACAACTGAAGTTAATAAACTTCAGAAGGGAATAGAAATGTACAATCAAGAGAA
TTCAGTATATTTGTCATATGAAAAGAGGGCTGAGACTTTAGCTGTTGAGATAAAAGAGCTTCAAGGACAACTAGCAGACTACAACATGTT
GGTAGATAAACTTAATACCAACACTGAAATGGAAGAAGTAATGAATGATTACAATATGCTTAAAGCTCAAAATGATCGAGAAACACAAAG
TTTGGATGTCATATTTACTGAAAGACAAGCGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAGGTTT
GGAATTAAAACAAGGAAAAGGGGAAGATAGTGATGTACTCAGTATAAATGCAGATGCTTATGACAGCGACATAGAAGGCCCATGCAACGA
AGAAGCAGCTGCTCCCGAGGCACCAGAAAATACAGTCCAAAGTGAAGCTGGTCAGATAGATGACCTGGAGAAAGACATTGAGAAAAGTGT
GAATGAGATTCTAGGACTGGCAGAGTCTAGCCCAAACGAACCCAAAGCAGCCACCCTGGCTGTTCCTCCACCAGAAGATGTTCAACCTTC
TGCACAGCAACTGGAGCTGCTAGAACTTGAGATGAGGGCAAGAGCGATTAAAGCCCTAATGAAAGCTGGTGATATAAAAAAGCCAGCCTA
GGTATTTAACTTGATTTTGAATTTTAGGTATGTTTGAACAAAGCCACATCATTTAATTTTGTATCTAAAATTTATTTGGGGTCTTATATG
TTATTTCTCATGTAACCCTTATTAGGACTCATTTTAGCCCTAAATTACCTGTGGCTGTTTCTTTTTATTTTTTTGACTACTTTTATATTA
TAAATGTGTGTTACTGTCTTATGAATTCATGGCAATATAGTTGGATAGCCTGGATACTTTGTTAGATGAGTATTTAGCTGTGTCTGCAAA
TCTTAAAAGCCATTAGCAAAGAGTCGTGGTATTTTTTTCTTTATTTTTAAATGTTTGGGCACCAAACCTAAAAGCAAAAGATTGACGAAG
CATGTTTCTCTTAAGGCTACTTGTATTTTACAATACAATATTAAATTATTTAATTTGAGAAATTTAGTTTTGCTTATATGCACTTTTTAA
ATATATACTATTTTGAAGATTCCTTATGTAAATGCAAATTTCCTAGTTAAAACCGAATAACAGAGATCTGAAATGACTGAGAAAAACTTT

>38440_38440_2_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000380062_CAAP1_chr9_26861137_ENST00000535437_length(amino acids)=335AA_BP=196
MASNHKSSAARPVSRGGVGLTGRPPSGIRPLSGNIRVATAMPPGTARPGSRGCPIGTGGVLSSQIKVAHRPVTQQGLTGMKTGTKGPQRQ
ILDKSYYLGLLRSKISELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVEIKELQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQN
DRETQSLDVIFTERQAQDICIDSASSVRENKQPEGLELKQGKGEDSDVLSINADAYDSDIEGPCNEEAAAPEAPENTVQSEAGQIDDLEK

--------------------------------------------------------------
>38440_38440_3_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000429045_CAAP1_chr9_26861137_ENST00000333916_length(transcript)=2681nt_BP=644nt
GCGAGCCGGGCAACTGCCCTCCTTCCGCGCCGGCGGAGCGATTAAAGTGAAGAAACAATGGCCAGCAATCACAAATCTTCAGCAGCTCGC
CCTGTTTCAAGAGGTGGAGTTGGGTTAACAGGAAGGCCTCCTTCTGGGATACGACCCCTATCAGGAAATATTCGAGTGGCAACTGCAATG
CCACCTGGGACAGCAAGACCAGGTTCTCGTGGTTGTCCCATAGGGACTGGTGGAGTTCTGTCTTCTCAAATCAAAGTTGCCCATCGCCCT
GTAACACAACAAGGTTTGACTGGAATGAAAACTGGGACGAAAGGTCCCCAGAGGCAAATTTTAGACAAATCTTACTATCTTGGGCTTCTT
AGAAGTAAAATAAGTGAACTTACAACTGAAGTTAATAAACTTCAGAAGGGAATAGAAATGTACAATCAAGAGAATTCAGTATATTTGTCA
TATGAAAAGAGGGCTGAGACTTTAGCTGTTGAGATAAAAGAGCTTCAAGGACAACTAGCAGACTACAACATGTTGGTAGATAAACTTAAT
ACCAACACTGAAATGGAAGAAGTAATGAATGATTACAATATGCTTAAAGCTCAAAATGATCGAGAAACACAAAGTTTGGATGTCATATTT
ACTGAAAGACAAGCGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAGGTTTGGAATTAAAACAAGGA
AAAGGGGAAGATAGTGATGTACTCAGTATAAATGCAGATGCTTATGACAGCGACATAGAAGGCCCATGCAACGAAGAAGCAGCTGCTCCC
GAGGCACCAGAAAATACAGTCCAAAGTGAAGCTGGTCAGATAGATGACCTGGAGAAAGACATTGAGAAAAGTGTGAATGAGATTCTAGGA
CTGGCAGAGTCTAGCCCAAACGAACCCAAAGCAGCCACCCTGGCTGTTCCTCCACCAGAAGATGTTCAACCTTCTGCACAGCAACTGGAG
CTGCTAGAACTTGAGATGAGGGCAAGAGCGATTAAAGCCCTAATGAAAGCTGGTGATATAAAAAAGCCAGCCTAGGTATTTAACTTGATT
TTGAATTTTAGGTATGTTTGAACAAAGCCACATCATTTAATTTTGTATCTAAAATTTATTTGGGGTCTTATATGTTATTTCTCATGTAAC
CCTTATTAGGACTCATTTTAGCCCTAAATTACCTGTGGCTGTTTCTTTTTATTTTTTTGACTACTTTTATATTATAAATGTGTGTTACTG
TCTTATGAATTCATGGCAATATAGTTGGATAGCCTGGATACTTTGTTAGATGAGTATTTAGCTGTGTCTGCAAATCTTAAAAGCCATTAG
CAAAGAGTCGTGGTATTTTTTTCTTTATTTTTAAATGTTTGGGCACCAAACCTAAAAGCAAAAGATTGACGAAGCATGTTTCTCTTAAGG
CTACTTGTATTTTACAATACAATATTAAATTATTTAATTTGAGAAATTTAGTTTTGCTTATATGCACTTTTTAAATATATACTATTTTGA
AGATTCCTTATGTAAATGCAAATTTCCTAGTTAAAACCGAATAACAGAGATCTGAAATGACTGAGAAAAACTTTTTTATTAAAGGAAGGA
ATTAATTTAAGGCAATTTTTAACTATGTAGAACTAATTGCCCATGTTTAATTATAGCAGACACGCCATTCTAACAGGTATTTGATACCAT
TGGATGCATTATTCTAGGTTTTTTCTTTAATAAAAATGGAACAAGTTTTCATTTACATTCCAAGCTGTCAGGAAATGAAGAATATTTTAT
TATCTAGGATTTTATCTGATGTAGTTGCTTAAAGATCTGATGTGCTATAATTCCATGAATCAGAAATAATAAAATGCTATCATTCTGGAT
CTGAAGACTTTTGATACTTTTTCAAAAGCAAAATTAATTTCAGGAACCTTTGATAAGTTGTTGTTATAATTAATCTAATTTTGTATAGTT
TTTGTAAATAAATTACCATCCTTCCACAATTAGGGATGCTTTTATCCCCCCATCACTAATTGCAGTTGTTTGATACCAAAATAAATTTAC
GTAGAGATCCTTAACTTAAAATAAATTAATTTTTTCAAAAAACATAAATCTGGAACTGTTGTTTCTATATTTGATAACAAATACAGTATA
TTTTATTTATAAGCCATGGTCTACTGATACTGTATGAGGACTTTCCTTATATATAAAAGTTGCAGGGATTGTGTTTTATTAGCTGCTTTA
ATTATGTTAATTTTAGAGAGTTTTTAAATGGAAATAGAGGACATTTATGAAACGCTGGAATTGCAGTTACAAATTCTTTTTGTTGTTGTT
GTTCCTGAACATGCCTTGGAATAATTCTACCATTTTTTCCCCCTCCATAAATCTTTCTAATAAAGCATAGAAAAAGCCTATATGATTTTA
AATGCTTCTCTTAAGCTGGTAAACAGATTTGAGTTATGAGTTCATTGTTATTGCTTCAAGATGAAAAGACAGTGATATAATTTTTCTATT
TCAACTTAAAAGTAATAGTTAATATGCTAAAGTAGTACAGAATAAACTTTATTGCTGCTTACTAACTACAAAATACTGTAGATGGCATCT

>38440_38440_3_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000429045_CAAP1_chr9_26861137_ENST00000333916_length(amino acids)=335AA_BP=196
MASNHKSSAARPVSRGGVGLTGRPPSGIRPLSGNIRVATAMPPGTARPGSRGCPIGTGGVLSSQIKVAHRPVTQQGLTGMKTGTKGPQRQ
ILDKSYYLGLLRSKISELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVEIKELQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQN
DRETQSLDVIFTERQAQDICIDSASSVRENKQPEGLELKQGKGEDSDVLSINADAYDSDIEGPCNEEAAAPEAPENTVQSEAGQIDDLEK

--------------------------------------------------------------
>38440_38440_4_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000429045_CAAP1_chr9_26861137_ENST00000535437_length(transcript)=1630nt_BP=644nt
GCGAGCCGGGCAACTGCCCTCCTTCCGCGCCGGCGGAGCGATTAAAGTGAAGAAACAATGGCCAGCAATCACAAATCTTCAGCAGCTCGC
CCTGTTTCAAGAGGTGGAGTTGGGTTAACAGGAAGGCCTCCTTCTGGGATACGACCCCTATCAGGAAATATTCGAGTGGCAACTGCAATG
CCACCTGGGACAGCAAGACCAGGTTCTCGTGGTTGTCCCATAGGGACTGGTGGAGTTCTGTCTTCTCAAATCAAAGTTGCCCATCGCCCT
GTAACACAACAAGGTTTGACTGGAATGAAAACTGGGACGAAAGGTCCCCAGAGGCAAATTTTAGACAAATCTTACTATCTTGGGCTTCTT
AGAAGTAAAATAAGTGAACTTACAACTGAAGTTAATAAACTTCAGAAGGGAATAGAAATGTACAATCAAGAGAATTCAGTATATTTGTCA
TATGAAAAGAGGGCTGAGACTTTAGCTGTTGAGATAAAAGAGCTTCAAGGACAACTAGCAGACTACAACATGTTGGTAGATAAACTTAAT
ACCAACACTGAAATGGAAGAAGTAATGAATGATTACAATATGCTTAAAGCTCAAAATGATCGAGAAACACAAAGTTTGGATGTCATATTT
ACTGAAAGACAAGCGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAGGTTTGGAATTAAAACAAGGA
AAAGGGGAAGATAGTGATGTACTCAGTATAAATGCAGATGCTTATGACAGCGACATAGAAGGCCCATGCAACGAAGAAGCAGCTGCTCCC
GAGGCACCAGAAAATACAGTCCAAAGTGAAGCTGGTCAGATAGATGACCTGGAGAAAGACATTGAGAAAAGTGTGAATGAGATTCTAGGA
CTGGCAGAGTCTAGCCCAAACGAACCCAAAGCAGCCACCCTGGCTGTTCCTCCACCAGAAGATGTTCAACCTTCTGCACAGCAACTGGAG
CTGCTAGAACTTGAGATGAGGGCAAGAGCGATTAAAGCCCTAATGAAAGCTGGTGATATAAAAAAGCCAGCCTAGGTATTTAACTTGATT
TTGAATTTTAGGTATGTTTGAACAAAGCCACATCATTTAATTTTGTATCTAAAATTTATTTGGGGTCTTATATGTTATTTCTCATGTAAC
CCTTATTAGGACTCATTTTAGCCCTAAATTACCTGTGGCTGTTTCTTTTTATTTTTTTGACTACTTTTATATTATAAATGTGTGTTACTG
TCTTATGAATTCATGGCAATATAGTTGGATAGCCTGGATACTTTGTTAGATGAGTATTTAGCTGTGTCTGCAAATCTTAAAAGCCATTAG
CAAAGAGTCGTGGTATTTTTTTCTTTATTTTTAAATGTTTGGGCACCAAACCTAAAAGCAAAAGATTGACGAAGCATGTTTCTCTTAAGG
CTACTTGTATTTTACAATACAATATTAAATTATTTAATTTGAGAAATTTAGTTTTGCTTATATGCACTTTTTAAATATATACTATTTTGA
AGATTCCTTATGTAAATGCAAATTTCCTAGTTAAAACCGAATAACAGAGATCTGAAATGACTGAGAAAAACTTTTTTATTAAAGGAAGGA

>38440_38440_4_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000429045_CAAP1_chr9_26861137_ENST00000535437_length(amino acids)=335AA_BP=196
MASNHKSSAARPVSRGGVGLTGRPPSGIRPLSGNIRVATAMPPGTARPGSRGCPIGTGGVLSSQIKVAHRPVTQQGLTGMKTGTKGPQRQ
ILDKSYYLGLLRSKISELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVEIKELQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQN
DRETQSLDVIFTERQAQDICIDSASSVRENKQPEGLELKQGKGEDSDVLSINADAYDSDIEGPCNEEAAAPEAPENTVQSEAGQIDDLEK

--------------------------------------------------------------
>38440_38440_5_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000433700_CAAP1_chr9_26861137_ENST00000333916_length(transcript)=2751nt_BP=714nt
TCGTCATGGCCAGTGTCTGTCTGGCGCCCGGTGCCCAGGCACTGTGCGAGACCAGTCCGCAGGGGCGACTCGGAGAGCGCCGGGCCGCGG
CGGGAGAAGAGCCTGCAGCGATTAAAGTGAAGAAACAATGGCCAGCAATCACAAATCTTCAGCAGCTCGCCCTGTTTCAAGAGGTGGAGT
TGGGTTAACAGGAAGGCCTCCTTCTGGGATACGACCCCTATCAGGAAATATTCGAGTGGCAACTGCAATGCCACCTGGGACAGCAAGACC
AGGTTCTCGTGGTTGTCCCATAGGGACTGGTGGAGTTCTGTCTTCTCAAATCAAAGTTGCCCATCGCCCTGTAACACAACAAGGTTTGAC
TGGAATGAAAACTGGGACGAAAGGTCCCCAGAGGCAAATTTTAGACAAATCTTACTATCTTGGGCTTCTTAGAAGTAAAATAAGTGAACT
TACAACTGAAGTTAATAAACTTCAGAAGGGAATAGAAATGTACAATCAAGAGAATTCAGTATATTTGTCATATGAAAAGAGGGCTGAGAC
TTTAGCTGTTGAGATAAAAGAGCTTCAAGGACAACTAGCAGACTACAACATGTTGGTAGATAAACTTAATACCAACACTGAAATGGAAGA
AGTAATGAATGATTACAATATGCTTAAAGCTCAAAATGATCGAGAAACACAAAGTTTGGATGTCATATTTACTGAAAGACAAGCGCAAGA
CATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAGGTTTGGAATTAAAACAAGGAAAAGGGGAAGATAGTGATGT
ACTCAGTATAAATGCAGATGCTTATGACAGCGACATAGAAGGCCCATGCAACGAAGAAGCAGCTGCTCCCGAGGCACCAGAAAATACAGT
CCAAAGTGAAGCTGGTCAGATAGATGACCTGGAGAAAGACATTGAGAAAAGTGTGAATGAGATTCTAGGACTGGCAGAGTCTAGCCCAAA
CGAACCCAAAGCAGCCACCCTGGCTGTTCCTCCACCAGAAGATGTTCAACCTTCTGCACAGCAACTGGAGCTGCTAGAACTTGAGATGAG
GGCAAGAGCGATTAAAGCCCTAATGAAAGCTGGTGATATAAAAAAGCCAGCCTAGGTATTTAACTTGATTTTGAATTTTAGGTATGTTTG
AACAAAGCCACATCATTTAATTTTGTATCTAAAATTTATTTGGGGTCTTATATGTTATTTCTCATGTAACCCTTATTAGGACTCATTTTA
GCCCTAAATTACCTGTGGCTGTTTCTTTTTATTTTTTTGACTACTTTTATATTATAAATGTGTGTTACTGTCTTATGAATTCATGGCAAT
ATAGTTGGATAGCCTGGATACTTTGTTAGATGAGTATTTAGCTGTGTCTGCAAATCTTAAAAGCCATTAGCAAAGAGTCGTGGTATTTTT
TTCTTTATTTTTAAATGTTTGGGCACCAAACCTAAAAGCAAAAGATTGACGAAGCATGTTTCTCTTAAGGCTACTTGTATTTTACAATAC
AATATTAAATTATTTAATTTGAGAAATTTAGTTTTGCTTATATGCACTTTTTAAATATATACTATTTTGAAGATTCCTTATGTAAATGCA
AATTTCCTAGTTAAAACCGAATAACAGAGATCTGAAATGACTGAGAAAAACTTTTTTATTAAAGGAAGGAATTAATTTAAGGCAATTTTT
AACTATGTAGAACTAATTGCCCATGTTTAATTATAGCAGACACGCCATTCTAACAGGTATTTGATACCATTGGATGCATTATTCTAGGTT
TTTTCTTTAATAAAAATGGAACAAGTTTTCATTTACATTCCAAGCTGTCAGGAAATGAAGAATATTTTATTATCTAGGATTTTATCTGAT
GTAGTTGCTTAAAGATCTGATGTGCTATAATTCCATGAATCAGAAATAATAAAATGCTATCATTCTGGATCTGAAGACTTTTGATACTTT
TTCAAAAGCAAAATTAATTTCAGGAACCTTTGATAAGTTGTTGTTATAATTAATCTAATTTTGTATAGTTTTTGTAAATAAATTACCATC
CTTCCACAATTAGGGATGCTTTTATCCCCCCATCACTAATTGCAGTTGTTTGATACCAAAATAAATTTACGTAGAGATCCTTAACTTAAA
ATAAATTAATTTTTTCAAAAAACATAAATCTGGAACTGTTGTTTCTATATTTGATAACAAATACAGTATATTTTATTTATAAGCCATGGT
CTACTGATACTGTATGAGGACTTTCCTTATATATAAAAGTTGCAGGGATTGTGTTTTATTAGCTGCTTTAATTATGTTAATTTTAGAGAG
TTTTTAAATGGAAATAGAGGACATTTATGAAACGCTGGAATTGCAGTTACAAATTCTTTTTGTTGTTGTTGTTCCTGAACATGCCTTGGA
ATAATTCTACCATTTTTTCCCCCTCCATAAATCTTTCTAATAAAGCATAGAAAAAGCCTATATGATTTTAAATGCTTCTCTTAAGCTGGT
AAACAGATTTGAGTTATGAGTTCATTGTTATTGCTTCAAGATGAAAAGACAGTGATATAATTTTTCTATTTCAACTTAAAAGTAATAGTT
AATATGCTAAAGTAGTACAGAATAAACTTTATTGCTGCTTACTAACTACAAAATACTGTAGATGGCATCTGTATGATTAAACATATAAAG

>38440_38440_5_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000433700_CAAP1_chr9_26861137_ENST00000333916_length(amino acids)=335AA_BP=196
MASNHKSSAARPVSRGGVGLTGRPPSGIRPLSGNIRVATAMPPGTARPGSRGCPIGTGGVLSSQIKVAHRPVTQQGLTGMKTGTKGPQRQ
ILDKSYYLGLLRSKISELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVEIKELQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQN
DRETQSLDVIFTERQAQDICIDSASSVRENKQPEGLELKQGKGEDSDVLSINADAYDSDIEGPCNEEAAAPEAPENTVQSEAGQIDDLEK

--------------------------------------------------------------
>38440_38440_6_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000433700_CAAP1_chr9_26861137_ENST00000535437_length(transcript)=1700nt_BP=714nt
TCGTCATGGCCAGTGTCTGTCTGGCGCCCGGTGCCCAGGCACTGTGCGAGACCAGTCCGCAGGGGCGACTCGGAGAGCGCCGGGCCGCGG
CGGGAGAAGAGCCTGCAGCGATTAAAGTGAAGAAACAATGGCCAGCAATCACAAATCTTCAGCAGCTCGCCCTGTTTCAAGAGGTGGAGT
TGGGTTAACAGGAAGGCCTCCTTCTGGGATACGACCCCTATCAGGAAATATTCGAGTGGCAACTGCAATGCCACCTGGGACAGCAAGACC
AGGTTCTCGTGGTTGTCCCATAGGGACTGGTGGAGTTCTGTCTTCTCAAATCAAAGTTGCCCATCGCCCTGTAACACAACAAGGTTTGAC
TGGAATGAAAACTGGGACGAAAGGTCCCCAGAGGCAAATTTTAGACAAATCTTACTATCTTGGGCTTCTTAGAAGTAAAATAAGTGAACT
TACAACTGAAGTTAATAAACTTCAGAAGGGAATAGAAATGTACAATCAAGAGAATTCAGTATATTTGTCATATGAAAAGAGGGCTGAGAC
TTTAGCTGTTGAGATAAAAGAGCTTCAAGGACAACTAGCAGACTACAACATGTTGGTAGATAAACTTAATACCAACACTGAAATGGAAGA
AGTAATGAATGATTACAATATGCTTAAAGCTCAAAATGATCGAGAAACACAAAGTTTGGATGTCATATTTACTGAAAGACAAGCGCAAGA
CATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAGGTTTGGAATTAAAACAAGGAAAAGGGGAAGATAGTGATGT
ACTCAGTATAAATGCAGATGCTTATGACAGCGACATAGAAGGCCCATGCAACGAAGAAGCAGCTGCTCCCGAGGCACCAGAAAATACAGT
CCAAAGTGAAGCTGGTCAGATAGATGACCTGGAGAAAGACATTGAGAAAAGTGTGAATGAGATTCTAGGACTGGCAGAGTCTAGCCCAAA
CGAACCCAAAGCAGCCACCCTGGCTGTTCCTCCACCAGAAGATGTTCAACCTTCTGCACAGCAACTGGAGCTGCTAGAACTTGAGATGAG
GGCAAGAGCGATTAAAGCCCTAATGAAAGCTGGTGATATAAAAAAGCCAGCCTAGGTATTTAACTTGATTTTGAATTTTAGGTATGTTTG
AACAAAGCCACATCATTTAATTTTGTATCTAAAATTTATTTGGGGTCTTATATGTTATTTCTCATGTAACCCTTATTAGGACTCATTTTA
GCCCTAAATTACCTGTGGCTGTTTCTTTTTATTTTTTTGACTACTTTTATATTATAAATGTGTGTTACTGTCTTATGAATTCATGGCAAT
ATAGTTGGATAGCCTGGATACTTTGTTAGATGAGTATTTAGCTGTGTCTGCAAATCTTAAAAGCCATTAGCAAAGAGTCGTGGTATTTTT
TTCTTTATTTTTAAATGTTTGGGCACCAAACCTAAAAGCAAAAGATTGACGAAGCATGTTTCTCTTAAGGCTACTTGTATTTTACAATAC
AATATTAAATTATTTAATTTGAGAAATTTAGTTTTGCTTATATGCACTTTTTAAATATATACTATTTTGAAGATTCCTTATGTAAATGCA

>38440_38440_6_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000433700_CAAP1_chr9_26861137_ENST00000535437_length(amino acids)=335AA_BP=196
MASNHKSSAARPVSRGGVGLTGRPPSGIRPLSGNIRVATAMPPGTARPGSRGCPIGTGGVLSSQIKVAHRPVTQQGLTGMKTGTKGPQRQ
ILDKSYYLGLLRSKISELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVEIKELQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQN
DRETQSLDVIFTERQAQDICIDSASSVRENKQPEGLELKQGKGEDSDVLSINADAYDSDIEGPCNEEAAAPEAPENTVQSEAGQIDDLEK

--------------------------------------------------------------
>38440_38440_7_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000443698_CAAP1_chr9_26861137_ENST00000333916_length(transcript)=2795nt_BP=758nt
GACGCCGATGCGGAGCTGAGCTGGCTTTCCTCCAGGGCTCTGGACTCCCTGCTGAGCAAGAGAGAAAGAGGCCCGCCCTTCCACCAGGAC
GCCTGACCCTGGGGTCCTTCCCAAACCCGGGTCTCTTCCGACTCCGGGCCCAACAGTTTGTGCGATTAAAGTGAAGAAACAATGGCCAGC
AATCACAAATCTTCAGCAGCTCGCCCTGTTTCAAGAGGTGGAGTTGGGTTAACAGGAAGGCCTCCTTCTGGGATACGACCCCTATCAGGA
AATATTCGAGTGGCAACTGCAATGCCACCTGGGACAGCAAGACCAGGTTCTCGTGGTTGTCCCATAGGGACTGGTGGAGTTCTGTCTTCT
CAAATCAAAGTTGCCCATCGCCCTGTAACACAACAAGGTTTGACTGGAATGAAAACTGGGACGAAAGGTCCCCAGAGGCAAATTTTAGAC
AAATCTTACTATCTTGGGCTTCTTAGAAGTAAAATAAGTGAACTTACAACTGAAGTTAATAAACTTCAGAAGGGAATAGAAATGTACAAT
CAAGAGAATTCAGTATATTTGTCATATGAAAAGAGGGCTGAGACTTTAGCTGTTGAGATAAAAGAGCTTCAAGGACAACTAGCAGACTAC
AACATGTTGGTAGATAAACTTAATACCAACACTGAAATGGAAGAAGTAATGAATGATTACAATATGCTTAAAGCTCAAAATGATCGAGAA
ACACAAAGTTTGGATGTCATATTTACTGAAAGACAAGCGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCT
GAAGGTTTGGAATTAAAACAAGGAAAAGGGGAAGATAGTGATGTACTCAGTATAAATGCAGATGCTTATGACAGCGACATAGAAGGCCCA
TGCAACGAAGAAGCAGCTGCTCCCGAGGCACCAGAAAATACAGTCCAAAGTGAAGCTGGTCAGATAGATGACCTGGAGAAAGACATTGAG
AAAAGTGTGAATGAGATTCTAGGACTGGCAGAGTCTAGCCCAAACGAACCCAAAGCAGCCACCCTGGCTGTTCCTCCACCAGAAGATGTT
CAACCTTCTGCACAGCAACTGGAGCTGCTAGAACTTGAGATGAGGGCAAGAGCGATTAAAGCCCTAATGAAAGCTGGTGATATAAAAAAG
CCAGCCTAGGTATTTAACTTGATTTTGAATTTTAGGTATGTTTGAACAAAGCCACATCATTTAATTTTGTATCTAAAATTTATTTGGGGT
CTTATATGTTATTTCTCATGTAACCCTTATTAGGACTCATTTTAGCCCTAAATTACCTGTGGCTGTTTCTTTTTATTTTTTTGACTACTT
TTATATTATAAATGTGTGTTACTGTCTTATGAATTCATGGCAATATAGTTGGATAGCCTGGATACTTTGTTAGATGAGTATTTAGCTGTG
TCTGCAAATCTTAAAAGCCATTAGCAAAGAGTCGTGGTATTTTTTTCTTTATTTTTAAATGTTTGGGCACCAAACCTAAAAGCAAAAGAT
TGACGAAGCATGTTTCTCTTAAGGCTACTTGTATTTTACAATACAATATTAAATTATTTAATTTGAGAAATTTAGTTTTGCTTATATGCA
CTTTTTAAATATATACTATTTTGAAGATTCCTTATGTAAATGCAAATTTCCTAGTTAAAACCGAATAACAGAGATCTGAAATGACTGAGA
AAAACTTTTTTATTAAAGGAAGGAATTAATTTAAGGCAATTTTTAACTATGTAGAACTAATTGCCCATGTTTAATTATAGCAGACACGCC
ATTCTAACAGGTATTTGATACCATTGGATGCATTATTCTAGGTTTTTTCTTTAATAAAAATGGAACAAGTTTTCATTTACATTCCAAGCT
GTCAGGAAATGAAGAATATTTTATTATCTAGGATTTTATCTGATGTAGTTGCTTAAAGATCTGATGTGCTATAATTCCATGAATCAGAAA
TAATAAAATGCTATCATTCTGGATCTGAAGACTTTTGATACTTTTTCAAAAGCAAAATTAATTTCAGGAACCTTTGATAAGTTGTTGTTA
TAATTAATCTAATTTTGTATAGTTTTTGTAAATAAATTACCATCCTTCCACAATTAGGGATGCTTTTATCCCCCCATCACTAATTGCAGT
TGTTTGATACCAAAATAAATTTACGTAGAGATCCTTAACTTAAAATAAATTAATTTTTTCAAAAAACATAAATCTGGAACTGTTGTTTCT
ATATTTGATAACAAATACAGTATATTTTATTTATAAGCCATGGTCTACTGATACTGTATGAGGACTTTCCTTATATATAAAAGTTGCAGG
GATTGTGTTTTATTAGCTGCTTTAATTATGTTAATTTTAGAGAGTTTTTAAATGGAAATAGAGGACATTTATGAAACGCTGGAATTGCAG
TTACAAATTCTTTTTGTTGTTGTTGTTCCTGAACATGCCTTGGAATAATTCTACCATTTTTTCCCCCTCCATAAATCTTTCTAATAAAGC
ATAGAAAAAGCCTATATGATTTTAAATGCTTCTCTTAAGCTGGTAAACAGATTTGAGTTATGAGTTCATTGTTATTGCTTCAAGATGAAA
AGACAGTGATATAATTTTTCTATTTCAACTTAAAAGTAATAGTTAATATGCTAAAGTAGTACAGAATAAACTTTATTGCTGCTTACTAAC
TACAAAATACTGTAGATGGCATCTGTATGATTAAACATATAAAGTAAAACAGGTCTGAGGGCTTTGTAGATGATTAAAGTCTCCACCTTC

>38440_38440_7_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000443698_CAAP1_chr9_26861137_ENST00000333916_length(amino acids)=335AA_BP=196
MASNHKSSAARPVSRGGVGLTGRPPSGIRPLSGNIRVATAMPPGTARPGSRGCPIGTGGVLSSQIKVAHRPVTQQGLTGMKTGTKGPQRQ
ILDKSYYLGLLRSKISELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVEIKELQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQN
DRETQSLDVIFTERQAQDICIDSASSVRENKQPEGLELKQGKGEDSDVLSINADAYDSDIEGPCNEEAAAPEAPENTVQSEAGQIDDLEK

--------------------------------------------------------------
>38440_38440_8_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000443698_CAAP1_chr9_26861137_ENST00000535437_length(transcript)=1744nt_BP=758nt
GACGCCGATGCGGAGCTGAGCTGGCTTTCCTCCAGGGCTCTGGACTCCCTGCTGAGCAAGAGAGAAAGAGGCCCGCCCTTCCACCAGGAC
GCCTGACCCTGGGGTCCTTCCCAAACCCGGGTCTCTTCCGACTCCGGGCCCAACAGTTTGTGCGATTAAAGTGAAGAAACAATGGCCAGC
AATCACAAATCTTCAGCAGCTCGCCCTGTTTCAAGAGGTGGAGTTGGGTTAACAGGAAGGCCTCCTTCTGGGATACGACCCCTATCAGGA
AATATTCGAGTGGCAACTGCAATGCCACCTGGGACAGCAAGACCAGGTTCTCGTGGTTGTCCCATAGGGACTGGTGGAGTTCTGTCTTCT
CAAATCAAAGTTGCCCATCGCCCTGTAACACAACAAGGTTTGACTGGAATGAAAACTGGGACGAAAGGTCCCCAGAGGCAAATTTTAGAC
AAATCTTACTATCTTGGGCTTCTTAGAAGTAAAATAAGTGAACTTACAACTGAAGTTAATAAACTTCAGAAGGGAATAGAAATGTACAAT
CAAGAGAATTCAGTATATTTGTCATATGAAAAGAGGGCTGAGACTTTAGCTGTTGAGATAAAAGAGCTTCAAGGACAACTAGCAGACTAC
AACATGTTGGTAGATAAACTTAATACCAACACTGAAATGGAAGAAGTAATGAATGATTACAATATGCTTAAAGCTCAAAATGATCGAGAA
ACACAAAGTTTGGATGTCATATTTACTGAAAGACAAGCGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCT
GAAGGTTTGGAATTAAAACAAGGAAAAGGGGAAGATAGTGATGTACTCAGTATAAATGCAGATGCTTATGACAGCGACATAGAAGGCCCA
TGCAACGAAGAAGCAGCTGCTCCCGAGGCACCAGAAAATACAGTCCAAAGTGAAGCTGGTCAGATAGATGACCTGGAGAAAGACATTGAG
AAAAGTGTGAATGAGATTCTAGGACTGGCAGAGTCTAGCCCAAACGAACCCAAAGCAGCCACCCTGGCTGTTCCTCCACCAGAAGATGTT
CAACCTTCTGCACAGCAACTGGAGCTGCTAGAACTTGAGATGAGGGCAAGAGCGATTAAAGCCCTAATGAAAGCTGGTGATATAAAAAAG
CCAGCCTAGGTATTTAACTTGATTTTGAATTTTAGGTATGTTTGAACAAAGCCACATCATTTAATTTTGTATCTAAAATTTATTTGGGGT
CTTATATGTTATTTCTCATGTAACCCTTATTAGGACTCATTTTAGCCCTAAATTACCTGTGGCTGTTTCTTTTTATTTTTTTGACTACTT
TTATATTATAAATGTGTGTTACTGTCTTATGAATTCATGGCAATATAGTTGGATAGCCTGGATACTTTGTTAGATGAGTATTTAGCTGTG
TCTGCAAATCTTAAAAGCCATTAGCAAAGAGTCGTGGTATTTTTTTCTTTATTTTTAAATGTTTGGGCACCAAACCTAAAAGCAAAAGAT
TGACGAAGCATGTTTCTCTTAAGGCTACTTGTATTTTACAATACAATATTAAATTATTTAATTTGAGAAATTTAGTTTTGCTTATATGCA
CTTTTTAAATATATACTATTTTGAAGATTCCTTATGTAAATGCAAATTTCCTAGTTAAAACCGAATAACAGAGATCTGAAATGACTGAGA

>38440_38440_8_IFT74-CAAP1_IFT74_chr9_26990193_ENST00000443698_CAAP1_chr9_26861137_ENST00000535437_length(amino acids)=335AA_BP=196
MASNHKSSAARPVSRGGVGLTGRPPSGIRPLSGNIRVATAMPPGTARPGSRGCPIGTGGVLSSQIKVAHRPVTQQGLTGMKTGTKGPQRQ
ILDKSYYLGLLRSKISELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVEIKELQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQN
DRETQSLDVIFTERQAQDICIDSASSVRENKQPEGLELKQGKGEDSDVLSINADAYDSDIEGPCNEEAAAPEAPENTVQSEAGQIDDLEK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for IFT74-CAAP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for IFT74-CAAP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for IFT74-CAAP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource