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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:IGF1R-MAP7 (FusionGDB2 ID:38486)

Fusion Gene Summary for IGF1R-MAP7

check button Fusion gene summary
Fusion gene informationFusion gene name: IGF1R-MAP7
Fusion gene ID: 38486
HgeneTgene
Gene symbol

IGF1R

MAP7

Gene ID

3480

9053

Gene nameinsulin like growth factor 1 receptormicrotubule associated protein 7
SynonymsCD221|IGFIR|IGFR|JTK13E-MAP-115|EMAP115
Cytomap

15q26.3

6q23.3

Type of geneprotein-codingprotein-coding
Descriptioninsulin-like growth factor 1 receptorIGF-I receptorsoluble IGF1R variant 1soluble IGF1R variant 2ensconsinMAP-7dJ325F22.2 (microtubule-associated protein 7 (EMAP115, E-MAP-115))epithelial microtubule-associated protein of 115 kDa
Modification date2020032920200313
UniProtAcc.

Q8IWC1

Ensembl transtripts involved in fusion geneENST00000268035, ENST00000558762, 
ENST00000560432, 		ENST00000432797, 
ENST00000354570, ENST00000438100, 
ENST00000454590, ENST00000544465, 
Fusion gene scores* DoF score24 X 15 X 6=216014 X 12 X 7=1176
# samples 2515
** MAII scorelog2(25/2160*10)=-3.11103131238874
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1176*10)=-2.97085365434048
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: IGF1R [Title/Abstract] AND MAP7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointIGF1R(99251336)-MAP7(136742937), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneIGF1R

GO:0043066

negative regulation of apoptotic process

12556535

HgeneIGF1R

GO:0046328

regulation of JNK cascade

12556535

HgeneIGF1R

GO:0046777

protein autophosphorylation

1846292|7679099|11162456

HgeneIGF1R

GO:0048009

insulin-like growth factor receptor signaling pathway

7679099

HgeneIGF1R

GO:0048015

phosphatidylinositol-mediated signaling

7692086

HgeneIGF1R

GO:0051389

inactivation of MAPKK activity

12556535


check buttonFusion gene breakpoints across IGF1R (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MAP7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-3B-A9HL-01AIGF1Rchr15

99251336

-MAP7chr6

136742937

-
ChimerDB4SARCTCGA-3B-A9HL-01AIGF1Rchr15

99251336

+MAP7chr6

136742937

-


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Fusion Gene ORF analysis for IGF1R-MAP7

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000268035ENST00000432797IGF1Rchr15

99251336

+MAP7chr6

136742937

-
5CDS-5UTRENST00000558762ENST00000432797IGF1Rchr15

99251336

+MAP7chr6

136742937

-
In-frameENST00000268035ENST00000354570IGF1Rchr15

99251336

+MAP7chr6

136742937

-
In-frameENST00000268035ENST00000438100IGF1Rchr15

99251336

+MAP7chr6

136742937

-
In-frameENST00000268035ENST00000454590IGF1Rchr15

99251336

+MAP7chr6

136742937

-
In-frameENST00000268035ENST00000544465IGF1Rchr15

99251336

+MAP7chr6

136742937

-
In-frameENST00000558762ENST00000354570IGF1Rchr15

99251336

+MAP7chr6

136742937

-
In-frameENST00000558762ENST00000438100IGF1Rchr15

99251336

+MAP7chr6

136742937

-
In-frameENST00000558762ENST00000454590IGF1Rchr15

99251336

+MAP7chr6

136742937

-
In-frameENST00000558762ENST00000544465IGF1Rchr15

99251336

+MAP7chr6

136742937

-
intron-3CDSENST00000560432ENST00000354570IGF1Rchr15

99251336

+MAP7chr6

136742937

-
intron-3CDSENST00000560432ENST00000438100IGF1Rchr15

99251336

+MAP7chr6

136742937

-
intron-3CDSENST00000560432ENST00000454590IGF1Rchr15

99251336

+MAP7chr6

136742937

-
intron-3CDSENST00000560432ENST00000544465IGF1Rchr15

99251336

+MAP7chr6

136742937

-
intron-5UTRENST00000560432ENST00000432797IGF1Rchr15

99251336

+MAP7chr6

136742937

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000268035IGF1Rchr1599251336+ENST00000354570MAP7chr6136742937-492512516113433940
ENST00000268035IGF1Rchr1599251336+ENST00000454590MAP7chr6136742937-411912516113433940
ENST00000268035IGF1Rchr1599251336+ENST00000544465MAP7chr6136742937-388012516113433940
ENST00000268035IGF1Rchr1599251336+ENST00000438100MAP7chr6136742937-372112516113322903
ENST00000558762IGF1Rchr1599251336+ENST00000354570MAP7chr6136742937-485211785383360940
ENST00000558762IGF1Rchr1599251336+ENST00000454590MAP7chr6136742937-404611785383360940
ENST00000558762IGF1Rchr1599251336+ENST00000544465MAP7chr6136742937-380711785383360940
ENST00000558762IGF1Rchr1599251336+ENST00000438100MAP7chr6136742937-364811785383249903

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000268035ENST00000354570IGF1Rchr1599251336+MAP7chr6136742937-0.0004261180.9995739
ENST00000268035ENST00000454590IGF1Rchr1599251336+MAP7chr6136742937-0.0011524310.9988476
ENST00000268035ENST00000544465IGF1Rchr1599251336+MAP7chr6136742937-0.0016395810.99836046
ENST00000268035ENST00000438100IGF1Rchr1599251336+MAP7chr6136742937-0.0028196670.99718034
ENST00000558762ENST00000354570IGF1Rchr1599251336+MAP7chr6136742937-0.0003519440.9996481
ENST00000558762ENST00000454590IGF1Rchr1599251336+MAP7chr6136742937-0.0009582350.99904174
ENST00000558762ENST00000544465IGF1Rchr1599251336+MAP7chr6136742937-0.0013642470.9986357
ENST00000558762ENST00000438100IGF1Rchr1599251336+MAP7chr6136742937-0.0024930190.99750704

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Fusion Genomic Features for IGF1R-MAP7


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for IGF1R-MAP7


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:99251336/chr6:136742937)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MAP7

Q8IWC1

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Promotes the assembly and stability of microtubules. {ECO:0000269|PubMed:22142902, ECO:0000269|PubMed:24927501}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMAP7chr15:99251336chr6:136742937ENST00000354570018477_61222750.0Coiled coilOntology_term=ECO:0000255
TgeneMAP7chr15:99251336chr6:136742937ENST0000035457001889_15222750.0Coiled coilOntology_term=ECO:0000255
TgeneMAP7chr15:99251336chr6:136742937ENST00000432797018477_6120604.0Coiled coilOntology_term=ECO:0000255
TgeneMAP7chr15:99251336chr6:136742937ENST0000043279701889_1520604.0Coiled coilOntology_term=ECO:0000255
TgeneMAP7chr15:99251336chr6:136742937ENST00000438100017477_61244735.0Coiled coilOntology_term=ECO:0000255
TgeneMAP7chr15:99251336chr6:136742937ENST0000043810001789_15244735.0Coiled coilOntology_term=ECO:0000255
TgeneMAP7chr15:99251336chr6:136742937ENST00000454590119477_61244772.0Coiled coilOntology_term=ECO:0000255
TgeneMAP7chr15:99251336chr6:136742937ENST0000045459011989_15244772.0Coiled coilOntology_term=ECO:0000255
TgeneMAP7chr15:99251336chr6:136742937ENST00000544465018477_6127735.0Coiled coilOntology_term=ECO:0000255
TgeneMAP7chr15:99251336chr6:136742937ENST0000054446501889_1527735.0Coiled coilOntology_term=ECO:0000255
TgeneMAP7chr15:99251336chr6:136742937ENST00000354570018316_45122750.0Compositional biasNote=Pro-rich
TgeneMAP7chr15:99251336chr6:136742937ENST00000432797018316_4510604.0Compositional biasNote=Pro-rich
TgeneMAP7chr15:99251336chr6:136742937ENST00000438100017316_45144735.0Compositional biasNote=Pro-rich
TgeneMAP7chr15:99251336chr6:136742937ENST00000454590119316_45144772.0Compositional biasNote=Pro-rich
TgeneMAP7chr15:99251336chr6:136742937ENST00000544465018316_4517735.0Compositional biasNote=Pro-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIGF1Rchr15:99251336chr6:136742937ENST00000268035+221491_6092131368.0DomainFibronectin type-III 1
HgeneIGF1Rchr15:99251336chr6:136742937ENST00000268035+221610_7082131368.0DomainFibronectin type-III 2
HgeneIGF1Rchr15:99251336chr6:136742937ENST00000268035+221735_8282131368.0DomainFibronectin type-III 3
HgeneIGF1Rchr15:99251336chr6:136742937ENST00000268035+221834_9272131368.0DomainFibronectin type-III 4
HgeneIGF1Rchr15:99251336chr6:136742937ENST00000268035+221999_12742131368.0DomainProtein kinase
HgeneIGF1Rchr15:99251336chr6:136742937ENST00000268035+221977_9802131368.0MotifNote=IRS1- and SHC1-binding
HgeneIGF1Rchr15:99251336chr6:136742937ENST00000268035+2211005_10132131368.0Nucleotide bindingATP
HgeneIGF1Rchr15:99251336chr6:136742937ENST00000268035+221741_9352131368.0Topological domainExtracellular
HgeneIGF1Rchr15:99251336chr6:136742937ENST00000268035+221960_13672131368.0Topological domainCytoplasmic
HgeneIGF1Rchr15:99251336chr6:136742937ENST00000268035+221936_9592131368.0TransmembraneHelical


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Fusion Gene Sequence for IGF1R-MAP7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>38486_38486_1_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000268035_MAP7_chr6_136742937_ENST00000354570_length(transcript)=4925nt_BP=1251nt
GGGAAGGAGCTCGCCGCGGCGGCGGCGGCGCTGAGGGAGGAGGCGGCGGCGAGCGGAGCCAGGAGGAGGAGGAGGAGGGGGAGCCGCTCA
TTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAACTGCGTCGCGCCCTCCCG
CGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGATTTGGGCTTTGCCCCCTT
TCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCCGGCGCGCCTCGGGTTCC
CGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCACCCGGAGGGCCCCGGCG
GCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGTTTCCTTTCATTTCCTTT
TTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAATGAAGTCTGGCTCCGGAG
GAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGAAATCTGCGGGCCAGGCA
TCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACATCCTGCTCATCTCCAAGG
CCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGCTGGCCTCGAGAGCCTCG
GAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGAGATGACCAATCTCAAGG
ATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTACCTCTCCACTGTGGACT
GGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCTGTGTCCAGGGACCATGG
AGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTGCCAGAAAACACCCGACA
GCTACAAAGTGCAAGATAAGAAAAATGCCTCCAGCCGCCCTGCCTCTGCAATTTCAGGACAAAATAACAACCACTCAGGAAATAAACCAG
ACCCTCCGCCTGTGTTACGTGTTGATGACCGGCAGCGGCTGGCCCGGGAGCGACGTGAGGAACGGGAGAAACAGCTAGCTGCAAGAGAAA
TAGTGTGGTTAGAAAGAGAAGAGCGAGCCAGGCAGCACTACGAGAAGCACCTGGAAGAGCGGAAGAAGAGGTTGGAGGAGCAGAGGCAGA
AGGAGGAGCGGAGGAGGGCTGCTGTGGAGGAGAAGCGGAGGCAGAGACTTGAGGAGGACAAAGAACGCCACGAAGCTGTTGTACGGCGCA
CAATGGAAAGGAGCCAGAAGCCAAAACAGAAGCATAACCGTTGGTCGTGGGGAGGCTCTCTCCATGGGAGCCCTAGCATCCACAGTGCAG
ATCCAGACAGGCGGTCAGTTTCCACCATGAATCTTTCGAAATATGTTGATCCCGTCATTAGCAAGCGGCTCTCCTCTTCATCTGCAACTT
TACTAAATTCTCCAGATAGAGCTCGCCGCCTGCAGCTCAGCCCATGGGAGAGCAGCGTTGTTAACAGACTCCTGACGCCCACACATTCGT
TCCTGGCCAGAAGTAAAAGCACAGCTGCCTTGTCTGGAGAAGCAGCATCTTGCAGCCCCATCATCATGCCCTACAAAGCTGCACACTCTA
GAAATTCGATGGATCGACCAAAACTCTTTGTAACACCACCTGAGGGCTCTTCTCGCAGGAGGATCATTCATGGCACAGCGAGCTATAAAA
AAGAAAGAGAGAGAGAAAATGTACTCTTCCTCACATCTGGCACCCGAAGGGCTGTATCTCCATCTAATCCCAAAGCAAGACAACCAGCTC
GCTCCCGACTTTGGCTTCCGTCCAAGTCTCTTCCTCATTTGCCTGGCACACCCAGACCGACATCCTCCTTGCCACCCGGCTCAGTCAAAG
CTGCTCCTGCTCAGGTCCGGCCCCCATCCCCCGGCAACATCCGCCCTGTCAAGAGGGAAGTCAAAGTGGAGCCTGAGAAGAAAGATCCTG
AGAAGGAACCTCAGAAAGTTGCCAATGAGCCCTCACTAAAGGGCAGAGCACCTTTAGTGAAGGTAGAAGAAGCCACAGTTGAAGAGCGGA
CACCTGCTGAACCAGAAGTTGGCCCTGCTGCTCCAGCCATGGCCCCAGCTCCAGCCTCGGCCCCAGCTCCAGCCTCGGCCCCAGCTCCAG
CCCCGGTCCCCACCCCAGCCATGGTCTCAGCCCCGTCATCCACTGTGAATGCCAGTGCTTCTGTTAAGACTTCTGCAGGCACCACCGACC
CAGAGGAGGCCACAAGGCTTCTAGCTGAGAAGAGGCGGCTGGCCCGAGAGCAGAGAGAAAAGGAAGAAAGGGAGAGGAGGGAGCAGGAAG
AGCTTGAAAGACAAAAGAGAGAGGAATTGGCTCAACGTGTGGCTGAAGAGAGGACGACTCGCCGTGAGGAGGAGTCGCGCAGGCTGGAAG
CCGAGCAGGCCCGGGAGAAGGAGGAGCAGCTGCAGCGGCAGGCGGAGGAGCGGGCGCTGCGCGAGCGGGAGGAGGCAGAGCGCGCCCAGA
GGCAGAAAGAAGAAGAAGCTCGCGTTCGTGAAGAAGCAGAGAGGGTCCGGCAGGAACGAGAGAAGCATTTCCAGAGAGAAGAGCAAGAGC
GCCTGGAGAGAAAGAAGCGACTTGAGGAGATTATGAAAAGAACCAGGAGAACAGAAGCTACAGATAAGAAAACCAGTGATCAGAGAAACG
GTGATATAGCCAAGGGAGCTCTCACTGGAGGAACAGAGGTGTCTGCACTTCCATGTACAACAAACGCTCCGGGAAATGGAAAGCCAGTTG
GCAGCCCACATGTGGTTACCTCACACCAGTCAAAAGTGACAGTGGAGAGCACTCCCGATTTGGAAAAACAACCAAATGAAAATGGTGTAT
CTGTTCAGAATGAAAATTTTGAAGAAATTATAAACTTACCCATTGGATCTAAACCATCCAGATTAGATGTCACCAACAGTGAGAGCCCAG
AAATTCCTTTGAATCCAATTTTGGCCTTTGATGATGAAGGGACACTTGGGCCCCTGCCTCAGGTAGATGGTGTTCAGACACAGCAGACTG
CAGAAGTTATATGAGTGTTTCTTCTGAAGAACCAAAGCTGAAATTTAATGAGAATTTCTACAATTAATGGAATTCCTTTCCTGCTATAAA
GGAGCATCCCCTCCACCCGTTTTCTAGAGTTCTTGACCATCATTTTGAAAAGATTTATTAAAACTAGCTAAAGACAACAGACTGGATAGC
TTTTCTAATAATTTTCATCAATAGGAAAAAAGAAATACGTCTCATTCTTCAATACTTTAAAATGGCTTTTTCCAGTGTGCTCCTTCTTAG
CAATCAATATTTTTCTGCATTCTTTAAAAGACAAGAGAATTTGGTTATAAAAGAAATGGGCTGACTAGGCATGATTTTTTTGGTCTTAAA
AGCTTAACATGTAAAATTGGCAAAAAAAATTTTTTACCTTTTATAATACTTGAAAAATAAGTACCTCTTTGTTCTACAAGTAGAATGAAT
AGGAGAAGAGTTTAAGCCTGTTTTTTTAAAATATTATTGCAAAGAGCTCTATTTGTAGAAGCAAATTATAGGCAGATTACCAGGTTCTTA
TAAATACAGCTTGTACATGGACATTCTGCAAACCCAGCTGTCACATTTTTCTTGCAACTCCTTTTGCAAAAGCAGACTAAAATGTTTTAA
AATGTGAAAAAACATTATTTTTTCAAAGCAAGAAAATAATTTACTGCCCTCTTACATAATGTATTTATAAAGTTTTTCCAGATAAACTAA
TCAAATAAATTAGAATAATGTGACAACATTACAAATTTAATTTGTTAGCTGCATTCCTTCTGATGTTACCACGATAGAATGTTACTGATG
ATTCAGGGCTATTTCTGAAGTCTGTATGTTGCTGCTGTCCCCAGTGATGGTGGACTTATCTTTGCCTTACCTGATCACAAATTATGTTGG
GGAAAATAAAGATTTAATATTTCTTTAAATAGAAAAAGAATTTGGTTTTGCTCGTTTAAGAGCAATGAGAAAATGATGGAATGTTGACTG
TGTTTGGCACACAGGACACGGACCTTCATGGAAGTCCTTGCTCTGCGTGGCATCTGTCAGCTTTTCACCTTTCATTCTTATTCTTCACTT
TTGCTGCTGAGCCTAGCTGTACAAACTTGCACTTTCATTTGCTAATATAAATTCAGTTTTATTTTACCATTTTAGAGACTACTAATGATT
AAATGTAGAAGGAGAGGGTGCACATGTTTTTATGTGGAGTGTTTAAAAGATAAATTTATACCACTGTAATGTGCAGCTTTTATTAAAAGA
GAAATTGGTTGAACTGCTAGGTTGAATGAGAGACTTCATCTATTGGACTATTTTTTTTAATCCAGGCATATGGTCTTTAGTAATGGCTTG
TAATTTGTGAAAACATTAATTTGGGGGTTTTCCCTGTTTTCAGTTGTCCATGTACACATAGTCATTATATTAGAAAAGAAATCTGTTCAA

>38486_38486_1_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000268035_MAP7_chr6_136742937_ENST00000354570_length(amino acids)=940AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKTPDSYKVQDKKNASSRPASAISGQNNNHSGNKPDPPPVLRVDDRQRLARERREEREK
QLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGS
PSIHSADPDRRSVSTMNLSKYVDPVISKRLSSSSATLLNSPDRARRLQLSPWESSVVNRLLTPTHSFLARSKSTAALSGEAASCSPIIMP
YKAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTASYKKERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSL
PPGSVKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAP
ASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREE
ESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKK
TSDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKPVGSPHVVTSHQSKVTVESTPDLEKQPNENGVSVQNENFEEIINLPIGSKPSRLDV

--------------------------------------------------------------
>38486_38486_2_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000268035_MAP7_chr6_136742937_ENST00000438100_length(transcript)=3721nt_BP=1251nt
GGGAAGGAGCTCGCCGCGGCGGCGGCGGCGCTGAGGGAGGAGGCGGCGGCGAGCGGAGCCAGGAGGAGGAGGAGGAGGGGGAGCCGCTCA
TTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAACTGCGTCGCGCCCTCCCG
CGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGATTTGGGCTTTGCCCCCTT
TCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCCGGCGCGCCTCGGGTTCC
CGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCACCCGGAGGGCCCCGGCG
GCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGTTTCCTTTCATTTCCTTT
TTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAATGAAGTCTGGCTCCGGAG
GAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGAAATCTGCGGGCCAGGCA
TCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACATCCTGCTCATCTCCAAGG
CCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGCTGGCCTCGAGAGCCTCG
GAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGAGATGACCAATCTCAAGG
ATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTACCTCTCCACTGTGGACT
GGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCTGTGTCCAGGGACCATGG
AGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTGCCAGAAAACACCCGACA
GCTACAAAGTGCAAGATAAGAAAAATGCCTCCAGCCGCCCTGCCTCTGCAATTTCAGGACAAAATAACAACCACTCAGGAAATAAACCAG
ACCCTCCGCCTGTGTTACGTGTTGATGACCGGCAGCGGCTGGCCCGGGAGCGACGTGAGGAACGGGAGAAACAGCTAGCTGCAAGAGAAA
TAGTGTGGTTAGAAAGAGAAGAGCGAGCCAGGCAGCACTACGAGAAGCACCTGGAAGAGCGGAAGAAGAGGTTGGAGGAGCAGAGGCAGA
AGGAGGAGCGGAGGAGGGCTGCTGTGGAGGAGAAGCGGAGGCAGAGACTTGAGGAGGACAAAGAACGCCACGAAGCTGTTGTACGGCGCA
CAATGGAAAGGAGCCAGAAGCCAAAACAGAAGCATAACCGTTGGTCGTGGGGAGGCTCTCTCCATGGGAGCCCTAGCATCCACAGTGCAG
CTCGCCGCCTGCAGCTCAGCCCATGGGAGAGCAGCGTTGTTAACAGACTCCTGACGCCCACACATTCGTTCCTGGCCAGAAGTAAAAGCA
CAGCTGCCTTGTCTGGAGAAGCAGCATCTTGCAGCCCCATCATCATGCCCTACAAAGCTGCACACTCTAGAAATTCGATGGATCGACCAA
AACTCTTTGTAACACCACCTGAGGGCTCTTCTCGCAGGAGGATCATTCATGGCACAGCGAGCTATAAAAAAGAAAGAGAGAGAGAAAATG
TACTCTTCCTCACATCTGGCACCCGAAGGGCTGTATCTCCATCTAATCCCAAAGCAAGACAACCAGCTCGCTCCCGACTTTGGCTTCCGT
CCAAGTCTCTTCCTCATTTGCCTGGCACACCCAGACCGACATCCTCCTTGCCACCCGGCTCAGTCAAAGCTGCTCCTGCTCAGGTCCGGC
CCCCATCCCCCGGCAACATCCGCCCTGTCAAGAGGGAAGTCAAAGTGGAGCCTGAGAAGAAAGATCCTGAGAAGGAACCTCAGAAAGTTG
CCAATGAGCCCTCACTAAAGGGCAGAGCACCTTTAGTGAAGGTAGAAGAAGCCACAGTTGAAGAGCGGACACCTGCTGAACCAGAAGTTG
GCCCTGCTGCTCCAGCCATGGCCCCAGCTCCAGCCTCGGCCCCAGCTCCAGCCTCGGCCCCAGCTCCAGCCCCGGTCCCCACCCCAGCCA
TGGTCTCAGCCCCGTCATCCACTGTGAATGCCAGTGCTTCTGTTAAGACTTCTGCAGGCACCACCGACCCAGAGGAGGCCACAAGGCTTC
TAGCTGAGAAGAGGCGGCTGGCCCGAGAGCAGAGAGAAAAGGAAGAAAGGGAGAGGAGGGAGCAGGAAGAGCTTGAAAGACAAAAGAGAG
AGGAATTGGCTCAACGTGTGGCTGAAGAGAGGACGACTCGCCGTGAGGAGGAGTCGCGCAGGCTGGAAGCCGAGCAGGCCCGGGAGAAGG
AGGAGCAGCTGCAGCGGCAGGCGGAGGAGCGGGCGCTGCGCGAGCGGGAGGAGGCAGAGCGCGCCCAGAGGCAGAAAGAAGAAGAAGCTC
GCGTTCGTGAAGAAGCAGAGAGGGTCCGGCAGGAACGAGAGAAGCATTTCCAGAGAGAAGAGCAAGAGCGCCTGGAGAGAAAGAAGCGAC
TTGAGGAGATTATGAAAAGAACCAGGAGAACAGAAGCTACAGATAAGAAAACCAGTGATCAGAGAAACGGTGATATAGCCAAGGGAGCTC
TCACTGGAGGAACAGAGGTGTCTGCACTTCCATGTACAACAAACGCTCCGGGAAATGGAAAGCCAGTTGGCAGCCCACATGTGGTTACCT
CACACCAGTCAAAAGTGACAGTGGAGAGCACTCCCGATTTGGAAAAACAACCAAATGAAAATGGTGTATCTGTTCAGAATGAAAATTTTG
AAGAAATTATAAACTTACCCATTGGATCTAAACCATCCAGATTAGATGTCACCAACAGTGAGAGCCCAGAAATTCCTTTGAATCCAATTT
TGGCCTTTGATGATGAAGGGACACTTGGGCCCCTGCCTCAGGTAGATGGTGTTCAGACACAGCAGACTGCAGAAGTTATATGAGTGTTTC
TTCTGAAGAACCAAAGCTGAAATTTAATGAGAATTTCTACAATTAATGGAATTCCTTTCCTGCTATAAAGGAGCATCCCCTCCACCCGTT
TTCTAGAGTTCTTGACCATCATTTTGAAAAGATTTATTAAAACTAGCTAAAGACAACAGACTGGATAGCTTTTCTAATAATTTTCATCAA
TAGGAAAAAAGAAATACGTCTCATTCTTCAATACTTTAAAATGGCTTTTTCCAGTGTGCTCCTTCTTAGCAATCAATATTTTTCTGCATT
CTTTAAAAGACAAGAGAATTTGGTTATAAAAGAAATGGGCTGACTAGGCATGATTTTTTTGGTCTTAAAAGCTTAACATGTAAAATTGGC

>38486_38486_2_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000268035_MAP7_chr6_136742937_ENST00000438100_length(amino acids)=903AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKTPDSYKVQDKKNASSRPASAISGQNNNHSGNKPDPPPVLRVDDRQRLARERREEREK
QLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGS
PSIHSAARRLQLSPWESSVVNRLLTPTHSFLARSKSTAALSGEAASCSPIIMPYKAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTASYKK
ERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSLPPGSVKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPE
KEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDP
EEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQR
QKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKPVG
SPHVVTSHQSKVTVESTPDLEKQPNENGVSVQNENFEEIINLPIGSKPSRLDVTNSESPEIPLNPILAFDDEGTLGPLPQVDGVQTQQTA

--------------------------------------------------------------
>38486_38486_3_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000268035_MAP7_chr6_136742937_ENST00000454590_length(transcript)=4119nt_BP=1251nt
GGGAAGGAGCTCGCCGCGGCGGCGGCGGCGCTGAGGGAGGAGGCGGCGGCGAGCGGAGCCAGGAGGAGGAGGAGGAGGGGGAGCCGCTCA
TTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAACTGCGTCGCGCCCTCCCG
CGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGATTTGGGCTTTGCCCCCTT
TCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCCGGCGCGCCTCGGGTTCC
CGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCACCCGGAGGGCCCCGGCG
GCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGTTTCCTTTCATTTCCTTT
TTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAATGAAGTCTGGCTCCGGAG
GAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGAAATCTGCGGGCCAGGCA
TCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACATCCTGCTCATCTCCAAGG
CCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGCTGGCCTCGAGAGCCTCG
GAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGAGATGACCAATCTCAAGG
ATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTACCTCTCCACTGTGGACT
GGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCTGTGTCCAGGGACCATGG
AGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTGCCAGAAAACACCCGACA
GCTACAAAGTGCAAGATAAGAAAAATGCCTCCAGCCGCCCTGCCTCTGCAATTTCAGGACAAAATAACAACCACTCAGGAAATAAACCAG
ACCCTCCGCCTGTGTTACGTGTTGATGACCGGCAGCGGCTGGCCCGGGAGCGACGTGAGGAACGGGAGAAACAGCTAGCTGCAAGAGAAA
TAGTGTGGTTAGAAAGAGAAGAGCGAGCCAGGCAGCACTACGAGAAGCACCTGGAAGAGCGGAAGAAGAGGTTGGAGGAGCAGAGGCAGA
AGGAGGAGCGGAGGAGGGCTGCTGTGGAGGAGAAGCGGAGGCAGAGACTTGAGGAGGACAAAGAACGCCACGAAGCTGTTGTACGGCGCA
CAATGGAAAGGAGCCAGAAGCCAAAACAGAAGCATAACCGTTGGTCGTGGGGAGGCTCTCTCCATGGGAGCCCTAGCATCCACAGTGCAG
ATCCAGACAGGCGGTCAGTTTCCACCATGAATCTTTCGAAATATGTTGATCCCGTCATTAGCAAGCGGCTCTCCTCTTCATCTGCAACTT
TACTAAATTCTCCAGATAGAGCTCGCCGCCTGCAGCTCAGCCCATGGGAGAGCAGCGTTGTTAACAGACTCCTGACGCCCACACATTCGT
TCCTGGCCAGAAGTAAAAGCACAGCTGCCTTGTCTGGAGAAGCAGCATCTTGCAGCCCCATCATCATGCCCTACAAAGCTGCACACTCTA
GAAATTCGATGGATCGACCAAAACTCTTTGTAACACCACCTGAGGGCTCTTCTCGCAGGAGGATCATTCATGGCACAGCGAGCTATAAAA
AAGAAAGAGAGAGAGAAAATGTACTCTTCCTCACATCTGGCACCCGAAGGGCTGTATCTCCATCTAATCCCAAAGCAAGACAACCAGCTC
GCTCCCGACTTTGGCTTCCGTCCAAGTCTCTTCCTCATTTGCCTGGCACACCCAGACCGACATCCTCCTTGCCACCCGGCTCAGTCAAAG
CTGCTCCTGCTCAGGTCCGGCCCCCATCCCCCGGCAACATCCGCCCTGTCAAGAGGGAAGTCAAAGTGGAGCCTGAGAAGAAAGATCCTG
AGAAGGAACCTCAGAAAGTTGCCAATGAGCCCTCACTAAAGGGCAGAGCACCTTTAGTGAAGGTAGAAGAAGCCACAGTTGAAGAGCGGA
CACCTGCTGAACCAGAAGTTGGCCCTGCTGCTCCAGCCATGGCCCCAGCTCCAGCCTCGGCCCCAGCTCCAGCCTCGGCCCCAGCTCCAG
CCCCGGTCCCCACCCCAGCCATGGTCTCAGCCCCGTCATCCACTGTGAATGCCAGTGCTTCTGTTAAGACTTCTGCAGGCACCACCGACC
CAGAGGAGGCCACAAGGCTTCTAGCTGAGAAGAGGCGGCTGGCCCGAGAGCAGAGAGAAAAGGAAGAAAGGGAGAGGAGGGAGCAGGAAG
AGCTTGAAAGACAAAAGAGAGAGGAATTGGCTCAACGTGTGGCTGAAGAGAGGACGACTCGCCGTGAGGAGGAGTCGCGCAGGCTGGAAG
CCGAGCAGGCCCGGGAGAAGGAGGAGCAGCTGCAGCGGCAGGCGGAGGAGCGGGCGCTGCGCGAGCGGGAGGAGGCAGAGCGCGCCCAGA
GGCAGAAAGAAGAAGAAGCTCGCGTTCGTGAAGAAGCAGAGAGGGTCCGGCAGGAACGAGAGAAGCATTTCCAGAGAGAAGAGCAAGAGC
GCCTGGAGAGAAAGAAGCGACTTGAGGAGATTATGAAAAGAACCAGGAGAACAGAAGCTACAGATAAGAAAACCAGTGATCAGAGAAACG
GTGATATAGCCAAGGGAGCTCTCACTGGAGGAACAGAGGTGTCTGCACTTCCATGTACAACAAACGCTCCGGGAAATGGAAAGCCAGTTG
GCAGCCCACATGTGGTTACCTCACACCAGTCAAAAGTGACAGTGGAGAGCACTCCCGATTTGGAAAAACAACCAAATGAAAATGGTGTAT
CTGTTCAGAATGAAAATTTTGAAGAAATTATAAACTTACCCATTGGATCTAAACCATCCAGATTAGATGTCACCAACAGTGAGAGCCCAG
AAATTCCTTTGAATCCAATTTTGGCCTTTGATGATGAAGGGACACTTGGGCCCCTGCCTCAGGTAGATGGTGTTCAGACACAGCAGACTG
CAGAAGTTATATGAGTGTTTCTTCTGAAGAACCAAAGCTGAAATTTAATGAGAATTTCTACAATTAATGGAATTCCTTTCCTGCTATAAA
GGAGCATCCCCTCCACCCGTTTTCTAGAGTTCTTGACCATCATTTTGAAAAGATTTATTAAAACTAGCTAAAGACAACAGACTGGATAGC
TTTTCTAATAATTTTCATCAATAGGAAAAAAGAAATACGTCTCATTCTTCAATACTTTAAAATGGCTTTTTCCAGTGTGCTCCTTCTTAG
CAATCAATATTTTTCTGCATTCTTTAAAAGACAAGAGAATTTGGTTATAAAAGAAATGGGCTGACTAGGCATGATTTTTTTGGTCTTAAA
AGCTTAACATGTAAAATTGGCAAAAAAAATTTTTTACCTTTTATAATACTTGAAAAATAAGTACCTCTTTGTTCTACAAGTAGAATGAAT
AGGAGAAGAGTTTAAGCCTGTTTTTTTAAAATATTATTGCAAAGAGCTCTATTTGTAGAAGCAAATTATAGGCAGATTACCAGGTTCTTA
TAAATACAGCTTGTACATGGACATTCTGCAAACCCAGCTGTCACATTTTTCTTGCAACTCCTTTTGCAAAAGCAGACTAAAATGTTTTAA

>38486_38486_3_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000268035_MAP7_chr6_136742937_ENST00000454590_length(amino acids)=940AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKTPDSYKVQDKKNASSRPASAISGQNNNHSGNKPDPPPVLRVDDRQRLARERREEREK
QLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGS
PSIHSADPDRRSVSTMNLSKYVDPVISKRLSSSSATLLNSPDRARRLQLSPWESSVVNRLLTPTHSFLARSKSTAALSGEAASCSPIIMP
YKAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTASYKKERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSL
PPGSVKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAP
ASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREE
ESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKK
TSDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKPVGSPHVVTSHQSKVTVESTPDLEKQPNENGVSVQNENFEEIINLPIGSKPSRLDV

--------------------------------------------------------------
>38486_38486_4_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000268035_MAP7_chr6_136742937_ENST00000544465_length(transcript)=3880nt_BP=1251nt
GGGAAGGAGCTCGCCGCGGCGGCGGCGGCGCTGAGGGAGGAGGCGGCGGCGAGCGGAGCCAGGAGGAGGAGGAGGAGGGGGAGCCGCTCA
TTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAACTGCGTCGCGCCCTCCCG
CGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGATTTGGGCTTTGCCCCCTT
TCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCCGGCGCGCCTCGGGTTCC
CGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCACCCGGAGGGCCCCGGCG
GCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGTTTCCTTTCATTTCCTTT
TTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAATGAAGTCTGGCTCCGGAG
GAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGAAATCTGCGGGCCAGGCA
TCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACATCCTGCTCATCTCCAAGG
CCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGCTGGCCTCGAGAGCCTCG
GAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGAGATGACCAATCTCAAGG
ATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTACCTCTCCACTGTGGACT
GGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCTGTGTCCAGGGACCATGG
AGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTGCCAGAAAACACCCGACA
GCTACAAAGTGCAAGATAAGAAAAATGCCTCCAGCCGCCCTGCCTCTGCAATTTCAGGACAAAATAACAACCACTCAGGAAATAAACCAG
ACCCTCCGCCTGTGTTACGTGTTGATGACCGGCAGCGGCTGGCCCGGGAGCGACGTGAGGAACGGGAGAAACAGCTAGCTGCAAGAGAAA
TAGTGTGGTTAGAAAGAGAAGAGCGAGCCAGGCAGCACTACGAGAAGCACCTGGAAGAGCGGAAGAAGAGGTTGGAGGAGCAGAGGCAGA
AGGAGGAGCGGAGGAGGGCTGCTGTGGAGGAGAAGCGGAGGCAGAGACTTGAGGAGGACAAAGAACGCCACGAAGCTGTTGTACGGCGCA
CAATGGAAAGGAGCCAGAAGCCAAAACAGAAGCATAACCGTTGGTCGTGGGGAGGCTCTCTCCATGGGAGCCCTAGCATCCACAGTGCAG
ATCCAGACAGGCGGTCAGTTTCCACCATGAATCTTTCGAAATATGTTGATCCCGTCATTAGCAAGCGGCTCTCCTCTTCATCTGCAACTT
TACTAAATTCTCCAGATAGAGCTCGCCGCCTGCAGCTCAGCCCATGGGAGAGCAGCGTTGTTAACAGACTCCTGACGCCCACACATTCGT
TCCTGGCCAGAAGTAAAAGCACAGCTGCCTTGTCTGGAGAAGCAGCATCTTGCAGCCCCATCATCATGCCCTACAAAGCTGCACACTCTA
GAAATTCGATGGATCGACCAAAACTCTTTGTAACACCACCTGAGGGCTCTTCTCGCAGGAGGATCATTCATGGCACAGCGAGCTATAAAA
AAGAAAGAGAGAGAGAAAATGTACTCTTCCTCACATCTGGCACCCGAAGGGCTGTATCTCCATCTAATCCCAAAGCAAGACAACCAGCTC
GCTCCCGACTTTGGCTTCCGTCCAAGTCTCTTCCTCATTTGCCTGGCACACCCAGACCGACATCCTCCTTGCCACCCGGCTCAGTCAAAG
CTGCTCCTGCTCAGGTCCGGCCCCCATCCCCCGGCAACATCCGCCCTGTCAAGAGGGAAGTCAAAGTGGAGCCTGAGAAGAAAGATCCTG
AGAAGGAACCTCAGAAAGTTGCCAATGAGCCCTCACTAAAGGGCAGAGCACCTTTAGTGAAGGTAGAAGAAGCCACAGTTGAAGAGCGGA
CACCTGCTGAACCAGAAGTTGGCCCTGCTGCTCCAGCCATGGCCCCAGCTCCAGCCTCGGCCCCAGCTCCAGCCTCGGCCCCAGCTCCAG
CCCCGGTCCCCACCCCAGCCATGGTCTCAGCCCCGTCATCCACTGTGAATGCCAGTGCTTCTGTTAAGACTTCTGCAGGCACCACCGACC
CAGAGGAGGCCACAAGGCTTCTAGCTGAGAAGAGGCGGCTGGCCCGAGAGCAGAGAGAAAAGGAAGAAAGGGAGAGGAGGGAGCAGGAAG
AGCTTGAAAGACAAAAGAGAGAGGAATTGGCTCAACGTGTGGCTGAAGAGAGGACGACTCGCCGTGAGGAGGAGTCGCGCAGGCTGGAAG
CCGAGCAGGCCCGGGAGAAGGAGGAGCAGCTGCAGCGGCAGGCGGAGGAGCGGGCGCTGCGCGAGCGGGAGGAGGCAGAGCGCGCCCAGA
GGCAGAAAGAAGAAGAAGCTCGCGTTCGTGAAGAAGCAGAGAGGGTCCGGCAGGAACGAGAGAAGCATTTCCAGAGAGAAGAGCAAGAGC
GCCTGGAGAGAAAGAAGCGACTTGAGGAGATTATGAAAAGAACCAGGAGAACAGAAGCTACAGATAAGAAAACCAGTGATCAGAGAAACG
GTGATATAGCCAAGGGAGCTCTCACTGGAGGAACAGAGGTGTCTGCACTTCCATGTACAACAAACGCTCCGGGAAATGGAAAGCCAGTTG
GCAGCCCACATGTGGTTACCTCACACCAGTCAAAAGTGACAGTGGAGAGCACTCCCGATTTGGAAAAACAACCAAATGAAAATGGTGTAT
CTGTTCAGAATGAAAATTTTGAAGAAATTATAAACTTACCCATTGGATCTAAACCATCCAGATTAGATGTCACCAACAGTGAGAGCCCAG
AAATTCCTTTGAATCCAATTTTGGCCTTTGATGATGAAGGGACACTTGGGCCCCTGCCTCAGGTAGATGGTGTTCAGACACAGCAGACTG
CAGAAGTTATATGAGTGTTTCTTCTGAAGAACCAAAGCTGAAATTTAATGAGAATTTCTACAATTAATGGAATTCCTTTCCTGCTATAAA
GGAGCATCCCCTCCACCCGTTTTCTAGAGTTCTTGACCATCATTTTGAAAAGATTTATTAAAACTAGCTAAAGACAACAGACTGGATAGC
TTTTCTAATAATTTTCATCAATAGGAAAAAAGAAATACGTCTCATTCTTCAATACTTTAAAATGGCTTTTTCCAGTGTGCTCCTTCTTAG
CAATCAATATTTTTCTGCATTCTTTAAAAGACAAGAGAATTTGGTTATAAAAGAAATGGGCTGACTAGGCATGATTTTTTTGGTCTTAAA
AGCTTAACATGTAAAATTGGCAAAAAAAATTTTTTACCTTTTATAATACTTGAAAAATAAGTACCTCTTTGTTCTACAAGTAGAATGAAT

>38486_38486_4_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000268035_MAP7_chr6_136742937_ENST00000544465_length(amino acids)=940AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKTPDSYKVQDKKNASSRPASAISGQNNNHSGNKPDPPPVLRVDDRQRLARERREEREK
QLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGS
PSIHSADPDRRSVSTMNLSKYVDPVISKRLSSSSATLLNSPDRARRLQLSPWESSVVNRLLTPTHSFLARSKSTAALSGEAASCSPIIMP
YKAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTASYKKERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSL
PPGSVKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAP
ASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREE
ESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKK
TSDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKPVGSPHVVTSHQSKVTVESTPDLEKQPNENGVSVQNENFEEIINLPIGSKPSRLDV

--------------------------------------------------------------
>38486_38486_5_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000558762_MAP7_chr6_136742937_ENST00000354570_length(transcript)=4852nt_BP=1178nt
GGAGGGGGAGCCGCTCATTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAAC
TGCGTCGCGCCCTCCCGCGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGAT
TTGGGCTTTGCCCCCTTTCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCC
GGCGCGCCTCGGGTTCCCGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCA
CCCGGAGGGCCCCGGCGGCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGT
TTCCTTTCATTTCCTTTTTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAAT
GAAGTCTGGCTCCGGAGGAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGA
AATCTGCGGGCCAGGCATCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACAT
CCTGCTCATCTCCAAGGCCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGC
TGGCCTCGAGAGCCTCGGAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGA
GATGACCAATCTCAAGGATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTA
CCTCTCCACTGTGGACTGGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCT
GTGTCCAGGGACCATGGAGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTG
CCAGAAAACACCCGACAGCTACAAAGTGCAAGATAAGAAAAATGCCTCCAGCCGCCCTGCCTCTGCAATTTCAGGACAAAATAACAACCA
CTCAGGAAATAAACCAGACCCTCCGCCTGTGTTACGTGTTGATGACCGGCAGCGGCTGGCCCGGGAGCGACGTGAGGAACGGGAGAAACA
GCTAGCTGCAAGAGAAATAGTGTGGTTAGAAAGAGAAGAGCGAGCCAGGCAGCACTACGAGAAGCACCTGGAAGAGCGGAAGAAGAGGTT
GGAGGAGCAGAGGCAGAAGGAGGAGCGGAGGAGGGCTGCTGTGGAGGAGAAGCGGAGGCAGAGACTTGAGGAGGACAAAGAACGCCACGA
AGCTGTTGTACGGCGCACAATGGAAAGGAGCCAGAAGCCAAAACAGAAGCATAACCGTTGGTCGTGGGGAGGCTCTCTCCATGGGAGCCC
TAGCATCCACAGTGCAGATCCAGACAGGCGGTCAGTTTCCACCATGAATCTTTCGAAATATGTTGATCCCGTCATTAGCAAGCGGCTCTC
CTCTTCATCTGCAACTTTACTAAATTCTCCAGATAGAGCTCGCCGCCTGCAGCTCAGCCCATGGGAGAGCAGCGTTGTTAACAGACTCCT
GACGCCCACACATTCGTTCCTGGCCAGAAGTAAAAGCACAGCTGCCTTGTCTGGAGAAGCAGCATCTTGCAGCCCCATCATCATGCCCTA
CAAAGCTGCACACTCTAGAAATTCGATGGATCGACCAAAACTCTTTGTAACACCACCTGAGGGCTCTTCTCGCAGGAGGATCATTCATGG
CACAGCGAGCTATAAAAAAGAAAGAGAGAGAGAAAATGTACTCTTCCTCACATCTGGCACCCGAAGGGCTGTATCTCCATCTAATCCCAA
AGCAAGACAACCAGCTCGCTCCCGACTTTGGCTTCCGTCCAAGTCTCTTCCTCATTTGCCTGGCACACCCAGACCGACATCCTCCTTGCC
ACCCGGCTCAGTCAAAGCTGCTCCTGCTCAGGTCCGGCCCCCATCCCCCGGCAACATCCGCCCTGTCAAGAGGGAAGTCAAAGTGGAGCC
TGAGAAGAAAGATCCTGAGAAGGAACCTCAGAAAGTTGCCAATGAGCCCTCACTAAAGGGCAGAGCACCTTTAGTGAAGGTAGAAGAAGC
CACAGTTGAAGAGCGGACACCTGCTGAACCAGAAGTTGGCCCTGCTGCTCCAGCCATGGCCCCAGCTCCAGCCTCGGCCCCAGCTCCAGC
CTCGGCCCCAGCTCCAGCCCCGGTCCCCACCCCAGCCATGGTCTCAGCCCCGTCATCCACTGTGAATGCCAGTGCTTCTGTTAAGACTTC
TGCAGGCACCACCGACCCAGAGGAGGCCACAAGGCTTCTAGCTGAGAAGAGGCGGCTGGCCCGAGAGCAGAGAGAAAAGGAAGAAAGGGA
GAGGAGGGAGCAGGAAGAGCTTGAAAGACAAAAGAGAGAGGAATTGGCTCAACGTGTGGCTGAAGAGAGGACGACTCGCCGTGAGGAGGA
GTCGCGCAGGCTGGAAGCCGAGCAGGCCCGGGAGAAGGAGGAGCAGCTGCAGCGGCAGGCGGAGGAGCGGGCGCTGCGCGAGCGGGAGGA
GGCAGAGCGCGCCCAGAGGCAGAAAGAAGAAGAAGCTCGCGTTCGTGAAGAAGCAGAGAGGGTCCGGCAGGAACGAGAGAAGCATTTCCA
GAGAGAAGAGCAAGAGCGCCTGGAGAGAAAGAAGCGACTTGAGGAGATTATGAAAAGAACCAGGAGAACAGAAGCTACAGATAAGAAAAC
CAGTGATCAGAGAAACGGTGATATAGCCAAGGGAGCTCTCACTGGAGGAACAGAGGTGTCTGCACTTCCATGTACAACAAACGCTCCGGG
AAATGGAAAGCCAGTTGGCAGCCCACATGTGGTTACCTCACACCAGTCAAAAGTGACAGTGGAGAGCACTCCCGATTTGGAAAAACAACC
AAATGAAAATGGTGTATCTGTTCAGAATGAAAATTTTGAAGAAATTATAAACTTACCCATTGGATCTAAACCATCCAGATTAGATGTCAC
CAACAGTGAGAGCCCAGAAATTCCTTTGAATCCAATTTTGGCCTTTGATGATGAAGGGACACTTGGGCCCCTGCCTCAGGTAGATGGTGT
TCAGACACAGCAGACTGCAGAAGTTATATGAGTGTTTCTTCTGAAGAACCAAAGCTGAAATTTAATGAGAATTTCTACAATTAATGGAAT
TCCTTTCCTGCTATAAAGGAGCATCCCCTCCACCCGTTTTCTAGAGTTCTTGACCATCATTTTGAAAAGATTTATTAAAACTAGCTAAAG
ACAACAGACTGGATAGCTTTTCTAATAATTTTCATCAATAGGAAAAAAGAAATACGTCTCATTCTTCAATACTTTAAAATGGCTTTTTCC
AGTGTGCTCCTTCTTAGCAATCAATATTTTTCTGCATTCTTTAAAAGACAAGAGAATTTGGTTATAAAAGAAATGGGCTGACTAGGCATG
ATTTTTTTGGTCTTAAAAGCTTAACATGTAAAATTGGCAAAAAAAATTTTTTACCTTTTATAATACTTGAAAAATAAGTACCTCTTTGTT
CTACAAGTAGAATGAATAGGAGAAGAGTTTAAGCCTGTTTTTTTAAAATATTATTGCAAAGAGCTCTATTTGTAGAAGCAAATTATAGGC
AGATTACCAGGTTCTTATAAATACAGCTTGTACATGGACATTCTGCAAACCCAGCTGTCACATTTTTCTTGCAACTCCTTTTGCAAAAGC
AGACTAAAATGTTTTAAAATGTGAAAAAACATTATTTTTTCAAAGCAAGAAAATAATTTACTGCCCTCTTACATAATGTATTTATAAAGT
TTTTCCAGATAAACTAATCAAATAAATTAGAATAATGTGACAACATTACAAATTTAATTTGTTAGCTGCATTCCTTCTGATGTTACCACG
ATAGAATGTTACTGATGATTCAGGGCTATTTCTGAAGTCTGTATGTTGCTGCTGTCCCCAGTGATGGTGGACTTATCTTTGCCTTACCTG
ATCACAAATTATGTTGGGGAAAATAAAGATTTAATATTTCTTTAAATAGAAAAAGAATTTGGTTTTGCTCGTTTAAGAGCAATGAGAAAA
TGATGGAATGTTGACTGTGTTTGGCACACAGGACACGGACCTTCATGGAAGTCCTTGCTCTGCGTGGCATCTGTCAGCTTTTCACCTTTC
ATTCTTATTCTTCACTTTTGCTGCTGAGCCTAGCTGTACAAACTTGCACTTTCATTTGCTAATATAAATTCAGTTTTATTTTACCATTTT
AGAGACTACTAATGATTAAATGTAGAAGGAGAGGGTGCACATGTTTTTATGTGGAGTGTTTAAAAGATAAATTTATACCACTGTAATGTG
CAGCTTTTATTAAAAGAGAAATTGGTTGAACTGCTAGGTTGAATGAGAGACTTCATCTATTGGACTATTTTTTTTAATCCAGGCATATGG
TCTTTAGTAATGGCTTGTAATTTGTGAAAACATTAATTTGGGGGTTTTCCCTGTTTTCAGTTGTCCATGTACACATAGTCATTATATTAG

>38486_38486_5_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000558762_MAP7_chr6_136742937_ENST00000354570_length(amino acids)=940AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKTPDSYKVQDKKNASSRPASAISGQNNNHSGNKPDPPPVLRVDDRQRLARERREEREK
QLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGS
PSIHSADPDRRSVSTMNLSKYVDPVISKRLSSSSATLLNSPDRARRLQLSPWESSVVNRLLTPTHSFLARSKSTAALSGEAASCSPIIMP
YKAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTASYKKERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSL
PPGSVKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAP
ASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREE
ESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKK
TSDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKPVGSPHVVTSHQSKVTVESTPDLEKQPNENGVSVQNENFEEIINLPIGSKPSRLDV

--------------------------------------------------------------
>38486_38486_6_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000558762_MAP7_chr6_136742937_ENST00000438100_length(transcript)=3648nt_BP=1178nt
GGAGGGGGAGCCGCTCATTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAAC
TGCGTCGCGCCCTCCCGCGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGAT
TTGGGCTTTGCCCCCTTTCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCC
GGCGCGCCTCGGGTTCCCGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCA
CCCGGAGGGCCCCGGCGGCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGT
TTCCTTTCATTTCCTTTTTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAAT
GAAGTCTGGCTCCGGAGGAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGA
AATCTGCGGGCCAGGCATCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACAT
CCTGCTCATCTCCAAGGCCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGC
TGGCCTCGAGAGCCTCGGAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGA
GATGACCAATCTCAAGGATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTA
CCTCTCCACTGTGGACTGGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCT
GTGTCCAGGGACCATGGAGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTG
CCAGAAAACACCCGACAGCTACAAAGTGCAAGATAAGAAAAATGCCTCCAGCCGCCCTGCCTCTGCAATTTCAGGACAAAATAACAACCA
CTCAGGAAATAAACCAGACCCTCCGCCTGTGTTACGTGTTGATGACCGGCAGCGGCTGGCCCGGGAGCGACGTGAGGAACGGGAGAAACA
GCTAGCTGCAAGAGAAATAGTGTGGTTAGAAAGAGAAGAGCGAGCCAGGCAGCACTACGAGAAGCACCTGGAAGAGCGGAAGAAGAGGTT
GGAGGAGCAGAGGCAGAAGGAGGAGCGGAGGAGGGCTGCTGTGGAGGAGAAGCGGAGGCAGAGACTTGAGGAGGACAAAGAACGCCACGA
AGCTGTTGTACGGCGCACAATGGAAAGGAGCCAGAAGCCAAAACAGAAGCATAACCGTTGGTCGTGGGGAGGCTCTCTCCATGGGAGCCC
TAGCATCCACAGTGCAGCTCGCCGCCTGCAGCTCAGCCCATGGGAGAGCAGCGTTGTTAACAGACTCCTGACGCCCACACATTCGTTCCT
GGCCAGAAGTAAAAGCACAGCTGCCTTGTCTGGAGAAGCAGCATCTTGCAGCCCCATCATCATGCCCTACAAAGCTGCACACTCTAGAAA
TTCGATGGATCGACCAAAACTCTTTGTAACACCACCTGAGGGCTCTTCTCGCAGGAGGATCATTCATGGCACAGCGAGCTATAAAAAAGA
AAGAGAGAGAGAAAATGTACTCTTCCTCACATCTGGCACCCGAAGGGCTGTATCTCCATCTAATCCCAAAGCAAGACAACCAGCTCGCTC
CCGACTTTGGCTTCCGTCCAAGTCTCTTCCTCATTTGCCTGGCACACCCAGACCGACATCCTCCTTGCCACCCGGCTCAGTCAAAGCTGC
TCCTGCTCAGGTCCGGCCCCCATCCCCCGGCAACATCCGCCCTGTCAAGAGGGAAGTCAAAGTGGAGCCTGAGAAGAAAGATCCTGAGAA
GGAACCTCAGAAAGTTGCCAATGAGCCCTCACTAAAGGGCAGAGCACCTTTAGTGAAGGTAGAAGAAGCCACAGTTGAAGAGCGGACACC
TGCTGAACCAGAAGTTGGCCCTGCTGCTCCAGCCATGGCCCCAGCTCCAGCCTCGGCCCCAGCTCCAGCCTCGGCCCCAGCTCCAGCCCC
GGTCCCCACCCCAGCCATGGTCTCAGCCCCGTCATCCACTGTGAATGCCAGTGCTTCTGTTAAGACTTCTGCAGGCACCACCGACCCAGA
GGAGGCCACAAGGCTTCTAGCTGAGAAGAGGCGGCTGGCCCGAGAGCAGAGAGAAAAGGAAGAAAGGGAGAGGAGGGAGCAGGAAGAGCT
TGAAAGACAAAAGAGAGAGGAATTGGCTCAACGTGTGGCTGAAGAGAGGACGACTCGCCGTGAGGAGGAGTCGCGCAGGCTGGAAGCCGA
GCAGGCCCGGGAGAAGGAGGAGCAGCTGCAGCGGCAGGCGGAGGAGCGGGCGCTGCGCGAGCGGGAGGAGGCAGAGCGCGCCCAGAGGCA
GAAAGAAGAAGAAGCTCGCGTTCGTGAAGAAGCAGAGAGGGTCCGGCAGGAACGAGAGAAGCATTTCCAGAGAGAAGAGCAAGAGCGCCT
GGAGAGAAAGAAGCGACTTGAGGAGATTATGAAAAGAACCAGGAGAACAGAAGCTACAGATAAGAAAACCAGTGATCAGAGAAACGGTGA
TATAGCCAAGGGAGCTCTCACTGGAGGAACAGAGGTGTCTGCACTTCCATGTACAACAAACGCTCCGGGAAATGGAAAGCCAGTTGGCAG
CCCACATGTGGTTACCTCACACCAGTCAAAAGTGACAGTGGAGAGCACTCCCGATTTGGAAAAACAACCAAATGAAAATGGTGTATCTGT
TCAGAATGAAAATTTTGAAGAAATTATAAACTTACCCATTGGATCTAAACCATCCAGATTAGATGTCACCAACAGTGAGAGCCCAGAAAT
TCCTTTGAATCCAATTTTGGCCTTTGATGATGAAGGGACACTTGGGCCCCTGCCTCAGGTAGATGGTGTTCAGACACAGCAGACTGCAGA
AGTTATATGAGTGTTTCTTCTGAAGAACCAAAGCTGAAATTTAATGAGAATTTCTACAATTAATGGAATTCCTTTCCTGCTATAAAGGAG
CATCCCCTCCACCCGTTTTCTAGAGTTCTTGACCATCATTTTGAAAAGATTTATTAAAACTAGCTAAAGACAACAGACTGGATAGCTTTT
CTAATAATTTTCATCAATAGGAAAAAAGAAATACGTCTCATTCTTCAATACTTTAAAATGGCTTTTTCCAGTGTGCTCCTTCTTAGCAAT
CAATATTTTTCTGCATTCTTTAAAAGACAAGAGAATTTGGTTATAAAAGAAATGGGCTGACTAGGCATGATTTTTTTGGTCTTAAAAGCT

>38486_38486_6_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000558762_MAP7_chr6_136742937_ENST00000438100_length(amino acids)=903AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKTPDSYKVQDKKNASSRPASAISGQNNNHSGNKPDPPPVLRVDDRQRLARERREEREK
QLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGS
PSIHSAARRLQLSPWESSVVNRLLTPTHSFLARSKSTAALSGEAASCSPIIMPYKAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTASYKK
ERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSLPPGSVKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPE
KEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDP
EEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQR
QKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKPVG
SPHVVTSHQSKVTVESTPDLEKQPNENGVSVQNENFEEIINLPIGSKPSRLDVTNSESPEIPLNPILAFDDEGTLGPLPQVDGVQTQQTA

--------------------------------------------------------------
>38486_38486_7_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000558762_MAP7_chr6_136742937_ENST00000454590_length(transcript)=4046nt_BP=1178nt
GGAGGGGGAGCCGCTCATTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAAC
TGCGTCGCGCCCTCCCGCGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGAT
TTGGGCTTTGCCCCCTTTCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCC
GGCGCGCCTCGGGTTCCCGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCA
CCCGGAGGGCCCCGGCGGCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGT
TTCCTTTCATTTCCTTTTTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAAT
GAAGTCTGGCTCCGGAGGAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGA
AATCTGCGGGCCAGGCATCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACAT
CCTGCTCATCTCCAAGGCCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGC
TGGCCTCGAGAGCCTCGGAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGA
GATGACCAATCTCAAGGATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTA
CCTCTCCACTGTGGACTGGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCT
GTGTCCAGGGACCATGGAGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTG
CCAGAAAACACCCGACAGCTACAAAGTGCAAGATAAGAAAAATGCCTCCAGCCGCCCTGCCTCTGCAATTTCAGGACAAAATAACAACCA
CTCAGGAAATAAACCAGACCCTCCGCCTGTGTTACGTGTTGATGACCGGCAGCGGCTGGCCCGGGAGCGACGTGAGGAACGGGAGAAACA
GCTAGCTGCAAGAGAAATAGTGTGGTTAGAAAGAGAAGAGCGAGCCAGGCAGCACTACGAGAAGCACCTGGAAGAGCGGAAGAAGAGGTT
GGAGGAGCAGAGGCAGAAGGAGGAGCGGAGGAGGGCTGCTGTGGAGGAGAAGCGGAGGCAGAGACTTGAGGAGGACAAAGAACGCCACGA
AGCTGTTGTACGGCGCACAATGGAAAGGAGCCAGAAGCCAAAACAGAAGCATAACCGTTGGTCGTGGGGAGGCTCTCTCCATGGGAGCCC
TAGCATCCACAGTGCAGATCCAGACAGGCGGTCAGTTTCCACCATGAATCTTTCGAAATATGTTGATCCCGTCATTAGCAAGCGGCTCTC
CTCTTCATCTGCAACTTTACTAAATTCTCCAGATAGAGCTCGCCGCCTGCAGCTCAGCCCATGGGAGAGCAGCGTTGTTAACAGACTCCT
GACGCCCACACATTCGTTCCTGGCCAGAAGTAAAAGCACAGCTGCCTTGTCTGGAGAAGCAGCATCTTGCAGCCCCATCATCATGCCCTA
CAAAGCTGCACACTCTAGAAATTCGATGGATCGACCAAAACTCTTTGTAACACCACCTGAGGGCTCTTCTCGCAGGAGGATCATTCATGG
CACAGCGAGCTATAAAAAAGAAAGAGAGAGAGAAAATGTACTCTTCCTCACATCTGGCACCCGAAGGGCTGTATCTCCATCTAATCCCAA
AGCAAGACAACCAGCTCGCTCCCGACTTTGGCTTCCGTCCAAGTCTCTTCCTCATTTGCCTGGCACACCCAGACCGACATCCTCCTTGCC
ACCCGGCTCAGTCAAAGCTGCTCCTGCTCAGGTCCGGCCCCCATCCCCCGGCAACATCCGCCCTGTCAAGAGGGAAGTCAAAGTGGAGCC
TGAGAAGAAAGATCCTGAGAAGGAACCTCAGAAAGTTGCCAATGAGCCCTCACTAAAGGGCAGAGCACCTTTAGTGAAGGTAGAAGAAGC
CACAGTTGAAGAGCGGACACCTGCTGAACCAGAAGTTGGCCCTGCTGCTCCAGCCATGGCCCCAGCTCCAGCCTCGGCCCCAGCTCCAGC
CTCGGCCCCAGCTCCAGCCCCGGTCCCCACCCCAGCCATGGTCTCAGCCCCGTCATCCACTGTGAATGCCAGTGCTTCTGTTAAGACTTC
TGCAGGCACCACCGACCCAGAGGAGGCCACAAGGCTTCTAGCTGAGAAGAGGCGGCTGGCCCGAGAGCAGAGAGAAAAGGAAGAAAGGGA
GAGGAGGGAGCAGGAAGAGCTTGAAAGACAAAAGAGAGAGGAATTGGCTCAACGTGTGGCTGAAGAGAGGACGACTCGCCGTGAGGAGGA
GTCGCGCAGGCTGGAAGCCGAGCAGGCCCGGGAGAAGGAGGAGCAGCTGCAGCGGCAGGCGGAGGAGCGGGCGCTGCGCGAGCGGGAGGA
GGCAGAGCGCGCCCAGAGGCAGAAAGAAGAAGAAGCTCGCGTTCGTGAAGAAGCAGAGAGGGTCCGGCAGGAACGAGAGAAGCATTTCCA
GAGAGAAGAGCAAGAGCGCCTGGAGAGAAAGAAGCGACTTGAGGAGATTATGAAAAGAACCAGGAGAACAGAAGCTACAGATAAGAAAAC
CAGTGATCAGAGAAACGGTGATATAGCCAAGGGAGCTCTCACTGGAGGAACAGAGGTGTCTGCACTTCCATGTACAACAAACGCTCCGGG
AAATGGAAAGCCAGTTGGCAGCCCACATGTGGTTACCTCACACCAGTCAAAAGTGACAGTGGAGAGCACTCCCGATTTGGAAAAACAACC
AAATGAAAATGGTGTATCTGTTCAGAATGAAAATTTTGAAGAAATTATAAACTTACCCATTGGATCTAAACCATCCAGATTAGATGTCAC
CAACAGTGAGAGCCCAGAAATTCCTTTGAATCCAATTTTGGCCTTTGATGATGAAGGGACACTTGGGCCCCTGCCTCAGGTAGATGGTGT
TCAGACACAGCAGACTGCAGAAGTTATATGAGTGTTTCTTCTGAAGAACCAAAGCTGAAATTTAATGAGAATTTCTACAATTAATGGAAT
TCCTTTCCTGCTATAAAGGAGCATCCCCTCCACCCGTTTTCTAGAGTTCTTGACCATCATTTTGAAAAGATTTATTAAAACTAGCTAAAG
ACAACAGACTGGATAGCTTTTCTAATAATTTTCATCAATAGGAAAAAAGAAATACGTCTCATTCTTCAATACTTTAAAATGGCTTTTTCC
AGTGTGCTCCTTCTTAGCAATCAATATTTTTCTGCATTCTTTAAAAGACAAGAGAATTTGGTTATAAAAGAAATGGGCTGACTAGGCATG
ATTTTTTTGGTCTTAAAAGCTTAACATGTAAAATTGGCAAAAAAAATTTTTTACCTTTTATAATACTTGAAAAATAAGTACCTCTTTGTT
CTACAAGTAGAATGAATAGGAGAAGAGTTTAAGCCTGTTTTTTTAAAATATTATTGCAAAGAGCTCTATTTGTAGAAGCAAATTATAGGC
AGATTACCAGGTTCTTATAAATACAGCTTGTACATGGACATTCTGCAAACCCAGCTGTCACATTTTTCTTGCAACTCCTTTTGCAAAAGC

>38486_38486_7_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000558762_MAP7_chr6_136742937_ENST00000454590_length(amino acids)=940AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKTPDSYKVQDKKNASSRPASAISGQNNNHSGNKPDPPPVLRVDDRQRLARERREEREK
QLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGS
PSIHSADPDRRSVSTMNLSKYVDPVISKRLSSSSATLLNSPDRARRLQLSPWESSVVNRLLTPTHSFLARSKSTAALSGEAASCSPIIMP
YKAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTASYKKERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSL
PPGSVKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAP
ASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREE
ESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKK
TSDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKPVGSPHVVTSHQSKVTVESTPDLEKQPNENGVSVQNENFEEIINLPIGSKPSRLDV

--------------------------------------------------------------
>38486_38486_8_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000558762_MAP7_chr6_136742937_ENST00000544465_length(transcript)=3807nt_BP=1178nt
GGAGGGGGAGCCGCTCATTCATTTTGACTCCGCGTTTCTGCCCCTCGCCGGCCTCGCCTGTGACCCGGACTTCGGGGCGATCTTGCGAAC
TGCGTCGCGCCCTCCCGCGGCGGAAGCTCGGGCGTCCGGCCGCCTCCCGCGCGGCCAGGGCCGGGCTTGTTTTTCCTCGCCTAGGCAGAT
TTGGGCTTTGCCCCCTTTCTTTGCAGTTTTCCCCCCTTCCTGCCTCTCCGGGTTTGAAAATGGAGGCCGACGACGCCGACAGCCCGCCCC
GGCGCGCCTCGGGTTCCCGACTCCGCCGAGCCCTGGGCCGCTGCTGCCGGCGCTGAGGGGCCGCCCCGCGCCGCCCGCCCCGTCCGCGCA
CCCGGAGGGCCCCGGCGGCGCCGCCTTCGGAGTATTGTTTCCTTCGCCCTTGTTTTTGGAGGGGGAGCGAAGACTGAGTTTGAGACTTGT
TTCCTTTCATTTCCTTTTTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGAAAGGGGAATTTCATCCCAAATAAAAGGAAT
GAAGTCTGGCTCCGGAGGAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGA
AATCTGCGGGCCAGGCATCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACAT
CCTGCTCATCTCCAAGGCCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGC
TGGCCTCGAGAGCCTCGGAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGA
GATGACCAATCTCAAGGATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTA
CCTCTCCACTGTGGACTGGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCT
GTGTCCAGGGACCATGGAGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTG
CCAGAAAACACCCGACAGCTACAAAGTGCAAGATAAGAAAAATGCCTCCAGCCGCCCTGCCTCTGCAATTTCAGGACAAAATAACAACCA
CTCAGGAAATAAACCAGACCCTCCGCCTGTGTTACGTGTTGATGACCGGCAGCGGCTGGCCCGGGAGCGACGTGAGGAACGGGAGAAACA
GCTAGCTGCAAGAGAAATAGTGTGGTTAGAAAGAGAAGAGCGAGCCAGGCAGCACTACGAGAAGCACCTGGAAGAGCGGAAGAAGAGGTT
GGAGGAGCAGAGGCAGAAGGAGGAGCGGAGGAGGGCTGCTGTGGAGGAGAAGCGGAGGCAGAGACTTGAGGAGGACAAAGAACGCCACGA
AGCTGTTGTACGGCGCACAATGGAAAGGAGCCAGAAGCCAAAACAGAAGCATAACCGTTGGTCGTGGGGAGGCTCTCTCCATGGGAGCCC
TAGCATCCACAGTGCAGATCCAGACAGGCGGTCAGTTTCCACCATGAATCTTTCGAAATATGTTGATCCCGTCATTAGCAAGCGGCTCTC
CTCTTCATCTGCAACTTTACTAAATTCTCCAGATAGAGCTCGCCGCCTGCAGCTCAGCCCATGGGAGAGCAGCGTTGTTAACAGACTCCT
GACGCCCACACATTCGTTCCTGGCCAGAAGTAAAAGCACAGCTGCCTTGTCTGGAGAAGCAGCATCTTGCAGCCCCATCATCATGCCCTA
CAAAGCTGCACACTCTAGAAATTCGATGGATCGACCAAAACTCTTTGTAACACCACCTGAGGGCTCTTCTCGCAGGAGGATCATTCATGG
CACAGCGAGCTATAAAAAAGAAAGAGAGAGAGAAAATGTACTCTTCCTCACATCTGGCACCCGAAGGGCTGTATCTCCATCTAATCCCAA
AGCAAGACAACCAGCTCGCTCCCGACTTTGGCTTCCGTCCAAGTCTCTTCCTCATTTGCCTGGCACACCCAGACCGACATCCTCCTTGCC
ACCCGGCTCAGTCAAAGCTGCTCCTGCTCAGGTCCGGCCCCCATCCCCCGGCAACATCCGCCCTGTCAAGAGGGAAGTCAAAGTGGAGCC
TGAGAAGAAAGATCCTGAGAAGGAACCTCAGAAAGTTGCCAATGAGCCCTCACTAAAGGGCAGAGCACCTTTAGTGAAGGTAGAAGAAGC
CACAGTTGAAGAGCGGACACCTGCTGAACCAGAAGTTGGCCCTGCTGCTCCAGCCATGGCCCCAGCTCCAGCCTCGGCCCCAGCTCCAGC
CTCGGCCCCAGCTCCAGCCCCGGTCCCCACCCCAGCCATGGTCTCAGCCCCGTCATCCACTGTGAATGCCAGTGCTTCTGTTAAGACTTC
TGCAGGCACCACCGACCCAGAGGAGGCCACAAGGCTTCTAGCTGAGAAGAGGCGGCTGGCCCGAGAGCAGAGAGAAAAGGAAGAAAGGGA
GAGGAGGGAGCAGGAAGAGCTTGAAAGACAAAAGAGAGAGGAATTGGCTCAACGTGTGGCTGAAGAGAGGACGACTCGCCGTGAGGAGGA
GTCGCGCAGGCTGGAAGCCGAGCAGGCCCGGGAGAAGGAGGAGCAGCTGCAGCGGCAGGCGGAGGAGCGGGCGCTGCGCGAGCGGGAGGA
GGCAGAGCGCGCCCAGAGGCAGAAAGAAGAAGAAGCTCGCGTTCGTGAAGAAGCAGAGAGGGTCCGGCAGGAACGAGAGAAGCATTTCCA
GAGAGAAGAGCAAGAGCGCCTGGAGAGAAAGAAGCGACTTGAGGAGATTATGAAAAGAACCAGGAGAACAGAAGCTACAGATAAGAAAAC
CAGTGATCAGAGAAACGGTGATATAGCCAAGGGAGCTCTCACTGGAGGAACAGAGGTGTCTGCACTTCCATGTACAACAAACGCTCCGGG
AAATGGAAAGCCAGTTGGCAGCCCACATGTGGTTACCTCACACCAGTCAAAAGTGACAGTGGAGAGCACTCCCGATTTGGAAAAACAACC
AAATGAAAATGGTGTATCTGTTCAGAATGAAAATTTTGAAGAAATTATAAACTTACCCATTGGATCTAAACCATCCAGATTAGATGTCAC
CAACAGTGAGAGCCCAGAAATTCCTTTGAATCCAATTTTGGCCTTTGATGATGAAGGGACACTTGGGCCCCTGCCTCAGGTAGATGGTGT
TCAGACACAGCAGACTGCAGAAGTTATATGAGTGTTTCTTCTGAAGAACCAAAGCTGAAATTTAATGAGAATTTCTACAATTAATGGAAT
TCCTTTCCTGCTATAAAGGAGCATCCCCTCCACCCGTTTTCTAGAGTTCTTGACCATCATTTTGAAAAGATTTATTAAAACTAGCTAAAG
ACAACAGACTGGATAGCTTTTCTAATAATTTTCATCAATAGGAAAAAAGAAATACGTCTCATTCTTCAATACTTTAAAATGGCTTTTTCC
AGTGTGCTCCTTCTTAGCAATCAATATTTTTCTGCATTCTTTAAAAGACAAGAGAATTTGGTTATAAAAGAAATGGGCTGACTAGGCATG
ATTTTTTTGGTCTTAAAAGCTTAACATGTAAAATTGGCAAAAAAAATTTTTTACCTTTTATAATACTTGAAAAATAAGTACCTCTTTGTT

>38486_38486_8_IGF1R-MAP7_IGF1R_chr15_99251336_ENST00000558762_MAP7_chr6_136742937_ENST00000544465_length(amino acids)=940AA_BP=214
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKTPDSYKVQDKKNASSRPASAISGQNNNHSGNKPDPPPVLRVDDRQRLARERREEREK
QLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGS
PSIHSADPDRRSVSTMNLSKYVDPVISKRLSSSSATLLNSPDRARRLQLSPWESSVVNRLLTPTHSFLARSKSTAALSGEAASCSPIIMP
YKAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTASYKKERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSL
PPGSVKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAP
ASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREE
ESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKK
TSDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKPVGSPHVVTSHQSKVTVESTPDLEKQPNENGVSVQNENFEEIINLPIGSKPSRLDV

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Fusion Gene PPI Analysis for IGF1R-MAP7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for IGF1R-MAP7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for IGF1R-MAP7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource