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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:ALDH5A1-DCDC2 (FusionGDB2 ID:3916) |
Fusion Gene Summary for ALDH5A1-DCDC2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ALDH5A1-DCDC2 | Fusion gene ID: 3916 | Hgene | Tgene | Gene symbol | ALDH5A1 | DCDC2 | Gene ID | 7915 | 51473 |
| Gene name | aldehyde dehydrogenase 5 family member A1 | doublecortin domain containing 2 | |
| Synonyms | SSADH|SSDH | DCDC2A|DFNB66|NPHP19|NSC|RU2|RU2S | |
| Cytomap | 6p22.3 | 6p22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | succinate-semialdehyde dehydrogenase, mitochondrialNAD(+)-dependent succinic semialdehyde dehydrogenasemitochondrial succinate semialdehyde dehydrogenase | doublecortin domain-containing protein 2 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | P51649 | Q9UHG0 | |
| Ensembl transtripts involved in fusion gene | ENST00000348925, ENST00000357578, ENST00000491546, ENST00000546278, | ENST00000378450, ENST00000378454, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 14 X 8 X 11=1232 |
| # samples | 2 | 16 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(16/1232*10)=-2.94485844580754 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ALDH5A1 [Title/Abstract] AND DCDC2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | ALDH5A1(24495578)-DCDC2(24178860), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ALDH5A1 | GO:0009450 | gamma-aminobutyric acid catabolic process | 9683595 |
| Fusion gene breakpoints across ALDH5A1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across DCDC2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LGG | TCGA-DU-7015 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - |
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Fusion Gene ORF analysis for ALDH5A1-DCDC2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000348925 | ENST00000378450 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - |
| In-frame | ENST00000348925 | ENST00000378454 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - |
| In-frame | ENST00000357578 | ENST00000378450 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - |
| In-frame | ENST00000357578 | ENST00000378454 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - |
| In-frame | ENST00000491546 | ENST00000378450 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - |
| In-frame | ENST00000491546 | ENST00000378454 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - |
| In-frame | ENST00000546278 | ENST00000378450 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - |
| In-frame | ENST00000546278 | ENST00000378454 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000546278 | ALDH5A1 | chr6 | 24495578 | + | ENST00000378454 | DCDC2 | chr6 | 24178860 | - | 3539 | 157 | 7 | 564 | 185 |
| ENST00000546278 | ALDH5A1 | chr6 | 24495578 | + | ENST00000378450 | DCDC2 | chr6 | 24178860 | - | 3539 | 157 | 7 | 564 | 185 |
| ENST00000357578 | ALDH5A1 | chr6 | 24495578 | + | ENST00000378454 | DCDC2 | chr6 | 24178860 | - | 3881 | 499 | 7 | 906 | 299 |
| ENST00000357578 | ALDH5A1 | chr6 | 24495578 | + | ENST00000378450 | DCDC2 | chr6 | 24178860 | - | 3881 | 499 | 7 | 906 | 299 |
| ENST00000491546 | ALDH5A1 | chr6 | 24495578 | + | ENST00000378454 | DCDC2 | chr6 | 24178860 | - | 3866 | 484 | 70 | 891 | 273 |
| ENST00000491546 | ALDH5A1 | chr6 | 24495578 | + | ENST00000378450 | DCDC2 | chr6 | 24178860 | - | 3866 | 484 | 70 | 891 | 273 |
| ENST00000348925 | ALDH5A1 | chr6 | 24495578 | + | ENST00000378454 | DCDC2 | chr6 | 24178860 | - | 3764 | 382 | 28 | 789 | 253 |
| ENST00000348925 | ALDH5A1 | chr6 | 24495578 | + | ENST00000378450 | DCDC2 | chr6 | 24178860 | - | 3764 | 382 | 28 | 789 | 253 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000546278 | ENST00000378454 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - | 0.000486979 | 0.99951303 |
| ENST00000546278 | ENST00000378450 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - | 0.000486979 | 0.99951303 |
| ENST00000357578 | ENST00000378454 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - | 0.001098798 | 0.9989011 |
| ENST00000357578 | ENST00000378450 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - | 0.001098798 | 0.9989011 |
| ENST00000491546 | ENST00000378454 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - | 0.001086383 | 0.99891365 |
| ENST00000491546 | ENST00000378450 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - | 0.001086383 | 0.99891365 |
| ENST00000348925 | ENST00000378454 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - | 0.001117057 | 0.99888295 |
| ENST00000348925 | ENST00000378450 | ALDH5A1 | chr6 | 24495578 | + | DCDC2 | chr6 | 24178860 | - | 0.001117057 | 0.99888295 |
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Fusion Genomic Features for ALDH5A1-DCDC2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for ALDH5A1-DCDC2 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:24495578/chr6:24178860) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ALDH5A1 | DCDC2 |
| FUNCTION: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). {ECO:0000269|PubMed:19300440}. | FUNCTION: Protein that plays a role in the inhibition of canonical Wnt signaling pathway (PubMed:25557784). May be involved in neuronal migration during development of the cerebral neocortex (By similarity). Involved in the control of ciliogenesis and ciliary length (PubMed:25601850, PubMed:27319779). {ECO:0000250|UniProtKB:D3ZR10, ECO:0000269|PubMed:25557784, ECO:0000269|PubMed:25601850, ECO:0000269|PubMed:27319779}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | DCDC2 | chr6:24495578 | chr6:24178860 | ENST00000378450 | 0 | 3 | 139_221 | 94 | 230.0 | Domain | Doublecortin 2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ALDH5A1 | chr6:24495578 | chr6:24178860 | ENST00000348925 | + | 1 | 11 | 202_204 | 118 | 549.0 | Nucleotide binding | NAD |
| Hgene | ALDH5A1 | chr6:24495578 | chr6:24178860 | ENST00000348925 | + | 1 | 11 | 228_231 | 118 | 549.0 | Nucleotide binding | NAD |
| Hgene | ALDH5A1 | chr6:24495578 | chr6:24178860 | ENST00000348925 | + | 1 | 11 | 284_289 | 118 | 549.0 | Nucleotide binding | NAD |
| Hgene | ALDH5A1 | chr6:24495578 | chr6:24178860 | ENST00000348925 | + | 1 | 11 | 438_440 | 118 | 549.0 | Nucleotide binding | NAD |
| Hgene | ALDH5A1 | chr6:24495578 | chr6:24178860 | ENST00000357578 | + | 1 | 10 | 202_204 | 118 | 536.0 | Nucleotide binding | NAD |
| Hgene | ALDH5A1 | chr6:24495578 | chr6:24178860 | ENST00000357578 | + | 1 | 10 | 228_231 | 118 | 536.0 | Nucleotide binding | NAD |
| Hgene | ALDH5A1 | chr6:24495578 | chr6:24178860 | ENST00000357578 | + | 1 | 10 | 284_289 | 118 | 536.0 | Nucleotide binding | NAD |
| Hgene | ALDH5A1 | chr6:24495578 | chr6:24178860 | ENST00000357578 | + | 1 | 10 | 438_440 | 118 | 536.0 | Nucleotide binding | NAD |
| Tgene | DCDC2 | chr6:24495578 | chr6:24178860 | ENST00000378450 | 0 | 3 | 17_100 | 94 | 230.0 | Domain | Doublecortin 1 | |
| Tgene | DCDC2 | chr6:24495578 | chr6:24178860 | ENST00000378454 | 7 | 10 | 139_221 | 341 | 477.0 | Domain | Doublecortin 2 | |
| Tgene | DCDC2 | chr6:24495578 | chr6:24178860 | ENST00000378454 | 7 | 10 | 17_100 | 341 | 477.0 | Domain | Doublecortin 1 |
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Fusion Gene Sequence for ALDH5A1-DCDC2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >3916_3916_1_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000348925_DCDC2_chr6_24178860_ENST00000378450_length(transcript)=3764nt_BP=382nt GTTTCCTGTCGCCGTCGTTGCCCGGGCCATGGCGACCTGCATTTGGCTGCGGAGCTGTGGGGCCCGGCGCCTCGGGTCGACGTTTCCAGG CTGCCGCCTCCGCCCCCGCGCCGGCGGCCTGGTCCCTGCCTCCGGGCCTGCGCCCGGCCCGGCCCAGCTCCGCTGCTACGCTGGGCGCCT GGCGGGCCTCTCTGCGGCGCTGCTGCGCACCGACAGCTTCGTGGGCGGCCGCTGGCTCCCGGCCGCCGCCACCTTCCCCGTGCAAGACCC GGCCAGCGGCGCCGCTCTGGGCATGGTAGCCGACTGCGGGGTGCGAGAGGCCCGCGCCGCCGTGCGCGCTGCCTACGAGGCTTTCTGCCG CTGGAGGGAGGTCTCCGCCAAGAGGCCAGCAGAAATAGTAGACGAGGAAGAAGATGGAGAGAAGGCAAACAAGGATGCAGAACAGAAAGA AGACTTTTCAGGAATGAATGGTGACCTTGAAGAGGAAGGAGGTAGGGAGGCTACAGATGCCCCTGAGCAAGTCGAGGAGATTCTGGATCA CAGTGAGCAGCAGGCACGCCCTGCTCGTGTAAATGGAGGCACCGATGAGGAGAATGGTGAGGAGCTGCAGCAGGTTAATAATGAGCTTCA ACTGGTCCTAGACAAGGAAAGAAAGTCTCAAGGAGCTGGCAGTGGACAAGATGAGGCTGATGTAGACCCTCAAAGACCACCAAGGCCAGA AGTAAAAATTACCAGTCCAGAAGAAAATGAAAACAACCAACAAAACAAGGACTATGCTGCCGTGGCTTAGAACATTTTTAAAAAGAGAGT ATATGGATCGCAAGAAAAATGAAGGGTTATCATACTTGAAAGATAAGCACATAGTTATTGCTGAATATAATGTGACACTATGGTCGAATA CTACCTACGAATTATAACATTAGAAGCCTAGTGGAAAGACCAGATAACTTTAAATGGCTACTAAAGGATAATTACTTACTTTTATTGCAT GTGTTTTAAAAGTCATATAGAAATATTAAATAAGACGGACAGAGGAGAATTTGCACTGGAAGACAATTGCCACTTGTAAAGGATGAAAAA TAGGATCACTCTTATTGTACGCTTTATTATAAGTTTAGAAGGCAGTTTATTCTAAATAATTTTTCTCTAGGAAGGCGTAGAATTTTAAAG AACTGGTAATAGGAAAGCATGTACTATTTTCTTAAAGCAATAAACTCTTGAATGAACAGATTGCGATTTACTTTCAGACATAATTTGGAG ATGGCAGTAGATCAAAATGTGTCCATGACTTGTTAACATGCCTTTCTTTCTTCCTCCTTAGCCAAAATCCACCTTTGAACTACAAAGACA GAGCAAGGCGTTCATTTTGGTGGGAGGAAGCATTGGTTCAGAGTGTTAGTGACTAGTATCGCCATGCCGTCACTTAAATGCTTTCAGGCT TGCATGCTTGTGGCTCCAATGGCGCACACTCAGGAAGGAATTGTAAAGGAGCACCCAGTTATATTATAAAGCCTGGATGTATGGTTTGCA GATAATGGAAATCCTGTGGATTTTCACTGATCCAGTCTATCTTTACCAATAGTATCTCTCTCTTCTCCCTTATGTTATTAGAGAACCTGA TATTGGCTATTCCAAAGATTAAATTATTTTCAAATAGTTTTCAACAAAAATAAAAGTGTATTAGGAAGAAAAAAGTAGACTATATGAAGA GTTTGTGACTGCTCAATTTAACTTGTTTTTTGCCTTATTTCTATTAAGACTGTTTTACTATGTTTTTGCCCTAGGGATATCAGCAAATAT TTATTTTTCCTAGCATGATATAGTTAGAATTTCAAGCAGATTTCTTTGTAATTAGAAGGCATCTGATAGAAATTGTAAAACTTTAGAAGT TATTATAATGAAACCAATTCCTGAATCACAACTTCATGGACTGACTAAATTGATTTATAGTTGCCTTGTGAGGTATGTATGGGGAAAACA TAAAAACATAATTAAAACATAATTTCGTCCTTTTTATGAATTCTTAAGAGATGTTCTTCCATAAATATAGAAATAATATATTTTTCTTAA AGGATATATTTTTAATTATGTGGAAGTTGTAAGCTTGAAATTTTAACTTCTAGTGCTTTTCTAAAATTCACAATTACAAGTTTAAAACAT TTTTTCTCTTCCAGGTTTCATTTGGAATAAAGAGTTGGCAGTTATATAAAGCACTTAATAATACTATAGAAAATAGATGTGTTTTTTCTT AATATGATTTTGGTATTTTCCACAGATCAGAAGTGTAAACAGAGAGATAATGTAACAGTATTTGGAAGAGATAATGACACAAGGATATAG TGATCTGGGAGCATGAATTAGAAACAGGGTACTATGTTTCTGGTGTAAAATCTAAATTGTGCTTTCTACTAGCGTTACTTTTTCAAATGG GATGATATAAAGCACTGTGGGCTATAAGCAACAATCTTGGGTTGGTAGGCAAATAGACCAATTGATCTTTATTATTATTATTATTATTAT TATTATTATTTTTTGAGATGAAGTCTTGCTCTTGTCGCCCAGGCTGGGTGCAGTGGCATGATCTTGGCTTACTGCAACCTCTGCCTCCTG GGTTCAAGCACCTGAGCCTCCCGAGTAGCTGGGATTACAGGCATCTGCCACCACACCTGGCTAATTTTTGTATTTTTTGTAGAGACAGAT GTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCGCCCGCCTTTGCATCCCAAAATGCTGGGATTACAGGTGT GAGCCACAGCACCCGGTCCCAGTTGGTCTTTTAATATTAAATTTGTGCACTATTACTGGGTCTGGAGTTAATGATTTCAAATAGTTTCTA AAAATAACTGATTAAATGTAAGAAATTATAACTAATTATCAAGGTGATTCTCTTTTGTTTCTTCAATGGAGAGTTTCTCTTTCTCTTTTC CTCCTCTAATAAAAATATTTCTTTTTTTCCTGTCCTTTTATTCATTATATTATGAAACTTAGGTTTTAGGAAACACCTTAAGCGTCATTT TAATGAAGCACAACATTGATATTTTACATGAATAATAACGTTTGGTATTTTAAATATACTTCAAGGGGGTAATAAGCCACAATAACTGTA CCAAAAAAACTTAAAAATGGGGACATATTCATCCCTTGTGTGTGCATATTTTACCACTTGTTGACAAGATACAATTGTGACCTACTTTGA GGGGATGAATAACGACTTATCACTTTAAGACACTTTGCAAACATGTTACTAAAAAAAGGTGCCTAGCCAAGGAAAAAACCATTCACTTGG AATTAAAATTGTGGATGTCACTTCAGAGATGACTTTAACATAAATGCTGAAAGTTCATTCACCTCACAAATGTGGCAGTTTTCTCTGTGG AGAATGGTGGTCTCCGTGGCAGACTGGCTCTCCAAATTAAATGAAACTCATTGACAGACCTGGGACCTTTTATGTGAGTGGACAGACAAG ATCTTGGTTTGGCTTCATGTACTGTTTTCTAGAGAGAGTGCTACGAAAAACTTATGATGCTTTTATGTGATAACCAATATAATGCTTTAA TATGTTAATTCTTTGTGATGCTATATACATAGTTTTTATAGTTTTATGAAACCACTTTGTTAAACTTATCTGGATTTTAAGACACTTGTA >3916_3916_1_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000348925_DCDC2_chr6_24178860_ENST00000378450_length(amino acids)=253AA_BP=118 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMV ADCGVREARAAVRAAYEAFCRWREVSAKRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGREATDAPEQVEEILDHSEQQARPAR -------------------------------------------------------------- >3916_3916_2_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000348925_DCDC2_chr6_24178860_ENST00000378454_length(transcript)=3764nt_BP=382nt GTTTCCTGTCGCCGTCGTTGCCCGGGCCATGGCGACCTGCATTTGGCTGCGGAGCTGTGGGGCCCGGCGCCTCGGGTCGACGTTTCCAGG CTGCCGCCTCCGCCCCCGCGCCGGCGGCCTGGTCCCTGCCTCCGGGCCTGCGCCCGGCCCGGCCCAGCTCCGCTGCTACGCTGGGCGCCT GGCGGGCCTCTCTGCGGCGCTGCTGCGCACCGACAGCTTCGTGGGCGGCCGCTGGCTCCCGGCCGCCGCCACCTTCCCCGTGCAAGACCC GGCCAGCGGCGCCGCTCTGGGCATGGTAGCCGACTGCGGGGTGCGAGAGGCCCGCGCCGCCGTGCGCGCTGCCTACGAGGCTTTCTGCCG CTGGAGGGAGGTCTCCGCCAAGAGGCCAGCAGAAATAGTAGACGAGGAAGAAGATGGAGAGAAGGCAAACAAGGATGCAGAACAGAAAGA AGACTTTTCAGGAATGAATGGTGACCTTGAAGAGGAAGGAGGTAGGGAGGCTACAGATGCCCCTGAGCAAGTCGAGGAGATTCTGGATCA CAGTGAGCAGCAGGCACGCCCTGCTCGTGTAAATGGAGGCACCGATGAGGAGAATGGTGAGGAGCTGCAGCAGGTTAATAATGAGCTTCA ACTGGTCCTAGACAAGGAAAGAAAGTCTCAAGGAGCTGGCAGTGGACAAGATGAGGCTGATGTAGACCCTCAAAGACCACCAAGGCCAGA AGTAAAAATTACCAGTCCAGAAGAAAATGAAAACAACCAACAAAACAAGGACTATGCTGCCGTGGCTTAGAACATTTTTAAAAAGAGAGT ATATGGATCGCAAGAAAAATGAAGGGTTATCATACTTGAAAGATAAGCACATAGTTATTGCTGAATATAATGTGACACTATGGTCGAATA CTACCTACGAATTATAACATTAGAAGCCTAGTGGAAAGACCAGATAACTTTAAATGGCTACTAAAGGATAATTACTTACTTTTATTGCAT GTGTTTTAAAAGTCATATAGAAATATTAAATAAGACGGACAGAGGAGAATTTGCACTGGAAGACAATTGCCACTTGTAAAGGATGAAAAA TAGGATCACTCTTATTGTACGCTTTATTATAAGTTTAGAAGGCAGTTTATTCTAAATAATTTTTCTCTAGGAAGGCGTAGAATTTTAAAG AACTGGTAATAGGAAAGCATGTACTATTTTCTTAAAGCAATAAACTCTTGAATGAACAGATTGCGATTTACTTTCAGACATAATTTGGAG ATGGCAGTAGATCAAAATGTGTCCATGACTTGTTAACATGCCTTTCTTTCTTCCTCCTTAGCCAAAATCCACCTTTGAACTACAAAGACA GAGCAAGGCGTTCATTTTGGTGGGAGGAAGCATTGGTTCAGAGTGTTAGTGACTAGTATCGCCATGCCGTCACTTAAATGCTTTCAGGCT TGCATGCTTGTGGCTCCAATGGCGCACACTCAGGAAGGAATTGTAAAGGAGCACCCAGTTATATTATAAAGCCTGGATGTATGGTTTGCA GATAATGGAAATCCTGTGGATTTTCACTGATCCAGTCTATCTTTACCAATAGTATCTCTCTCTTCTCCCTTATGTTATTAGAGAACCTGA TATTGGCTATTCCAAAGATTAAATTATTTTCAAATAGTTTTCAACAAAAATAAAAGTGTATTAGGAAGAAAAAAGTAGACTATATGAAGA GTTTGTGACTGCTCAATTTAACTTGTTTTTTGCCTTATTTCTATTAAGACTGTTTTACTATGTTTTTGCCCTAGGGATATCAGCAAATAT TTATTTTTCCTAGCATGATATAGTTAGAATTTCAAGCAGATTTCTTTGTAATTAGAAGGCATCTGATAGAAATTGTAAAACTTTAGAAGT TATTATAATGAAACCAATTCCTGAATCACAACTTCATGGACTGACTAAATTGATTTATAGTTGCCTTGTGAGGTATGTATGGGGAAAACA TAAAAACATAATTAAAACATAATTTCGTCCTTTTTATGAATTCTTAAGAGATGTTCTTCCATAAATATAGAAATAATATATTTTTCTTAA AGGATATATTTTTAATTATGTGGAAGTTGTAAGCTTGAAATTTTAACTTCTAGTGCTTTTCTAAAATTCACAATTACAAGTTTAAAACAT TTTTTCTCTTCCAGGTTTCATTTGGAATAAAGAGTTGGCAGTTATATAAAGCACTTAATAATACTATAGAAAATAGATGTGTTTTTTCTT AATATGATTTTGGTATTTTCCACAGATCAGAAGTGTAAACAGAGAGATAATGTAACAGTATTTGGAAGAGATAATGACACAAGGATATAG TGATCTGGGAGCATGAATTAGAAACAGGGTACTATGTTTCTGGTGTAAAATCTAAATTGTGCTTTCTACTAGCGTTACTTTTTCAAATGG GATGATATAAAGCACTGTGGGCTATAAGCAACAATCTTGGGTTGGTAGGCAAATAGACCAATTGATCTTTATTATTATTATTATTATTAT TATTATTATTTTTTGAGATGAAGTCTTGCTCTTGTCGCCCAGGCTGGGTGCAGTGGCATGATCTTGGCTTACTGCAACCTCTGCCTCCTG GGTTCAAGCACCTGAGCCTCCCGAGTAGCTGGGATTACAGGCATCTGCCACCACACCTGGCTAATTTTTGTATTTTTTGTAGAGACAGAT GTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCGCCCGCCTTTGCATCCCAAAATGCTGGGATTACAGGTGT GAGCCACAGCACCCGGTCCCAGTTGGTCTTTTAATATTAAATTTGTGCACTATTACTGGGTCTGGAGTTAATGATTTCAAATAGTTTCTA AAAATAACTGATTAAATGTAAGAAATTATAACTAATTATCAAGGTGATTCTCTTTTGTTTCTTCAATGGAGAGTTTCTCTTTCTCTTTTC CTCCTCTAATAAAAATATTTCTTTTTTTCCTGTCCTTTTATTCATTATATTATGAAACTTAGGTTTTAGGAAACACCTTAAGCGTCATTT TAATGAAGCACAACATTGATATTTTACATGAATAATAACGTTTGGTATTTTAAATATACTTCAAGGGGGTAATAAGCCACAATAACTGTA CCAAAAAAACTTAAAAATGGGGACATATTCATCCCTTGTGTGTGCATATTTTACCACTTGTTGACAAGATACAATTGTGACCTACTTTGA GGGGATGAATAACGACTTATCACTTTAAGACACTTTGCAAACATGTTACTAAAAAAAGGTGCCTAGCCAAGGAAAAAACCATTCACTTGG AATTAAAATTGTGGATGTCACTTCAGAGATGACTTTAACATAAATGCTGAAAGTTCATTCACCTCACAAATGTGGCAGTTTTCTCTGTGG AGAATGGTGGTCTCCGTGGCAGACTGGCTCTCCAAATTAAATGAAACTCATTGACAGACCTGGGACCTTTTATGTGAGTGGACAGACAAG ATCTTGGTTTGGCTTCATGTACTGTTTTCTAGAGAGAGTGCTACGAAAAACTTATGATGCTTTTATGTGATAACCAATATAATGCTTTAA TATGTTAATTCTTTGTGATGCTATATACATAGTTTTTATAGTTTTATGAAACCACTTTGTTAAACTTATCTGGATTTTAAGACACTTGTA >3916_3916_2_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000348925_DCDC2_chr6_24178860_ENST00000378454_length(amino acids)=253AA_BP=118 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMV ADCGVREARAAVRAAYEAFCRWREVSAKRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGREATDAPEQVEEILDHSEQQARPAR -------------------------------------------------------------- >3916_3916_3_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000357578_DCDC2_chr6_24178860_ENST00000378450_length(transcript)=3881nt_BP=499nt TGTGGCTCTGCAACCTTCCGCCAGCTCCCACGCTTTCCCCGCGCGTCCCCGGCGCCTCCTCGCTCCTCTTGCTTCCCCGCGACCCCTGCG TTCCCGTGCGCGCGCGCCCGCTTGCCTGTTTCCTGTCGCCGTCGTTGCCCGGGCCATGGCGACCTGCATTTGGCTGCGGAGCTGTGGGGC CCGGCGCCTCGGGTCGACGTTTCCAGGCTGCCGCCTCCGCCCCCGCGCCGGCGGCCTGGTCCCTGCCTCCGGGCCTGCGCCCGGCCCGGC CCAGCTCCGCTGCTACGCTGGGCGCCTGGCGGGCCTCTCTGCGGCGCTGCTGCGCACCGACAGCTTCGTGGGCGGCCGCTGGCTCCCGGC CGCCGCCACCTTCCCCGTGCAAGACCCGGCCAGCGGCGCCGCTCTGGGCATGGTAGCCGACTGCGGGGTGCGAGAGGCCCGCGCCGCCGT GCGCGCTGCCTACGAGGCTTTCTGCCGCTGGAGGGAGGTCTCCGCCAAGAGGCCAGCAGAAATAGTAGACGAGGAAGAAGATGGAGAGAA GGCAAACAAGGATGCAGAACAGAAAGAAGACTTTTCAGGAATGAATGGTGACCTTGAAGAGGAAGGAGGTAGGGAGGCTACAGATGCCCC TGAGCAAGTCGAGGAGATTCTGGATCACAGTGAGCAGCAGGCACGCCCTGCTCGTGTAAATGGAGGCACCGATGAGGAGAATGGTGAGGA GCTGCAGCAGGTTAATAATGAGCTTCAACTGGTCCTAGACAAGGAAAGAAAGTCTCAAGGAGCTGGCAGTGGACAAGATGAGGCTGATGT AGACCCTCAAAGACCACCAAGGCCAGAAGTAAAAATTACCAGTCCAGAAGAAAATGAAAACAACCAACAAAACAAGGACTATGCTGCCGT GGCTTAGAACATTTTTAAAAAGAGAGTATATGGATCGCAAGAAAAATGAAGGGTTATCATACTTGAAAGATAAGCACATAGTTATTGCTG AATATAATGTGACACTATGGTCGAATACTACCTACGAATTATAACATTAGAAGCCTAGTGGAAAGACCAGATAACTTTAAATGGCTACTA AAGGATAATTACTTACTTTTATTGCATGTGTTTTAAAAGTCATATAGAAATATTAAATAAGACGGACAGAGGAGAATTTGCACTGGAAGA CAATTGCCACTTGTAAAGGATGAAAAATAGGATCACTCTTATTGTACGCTTTATTATAAGTTTAGAAGGCAGTTTATTCTAAATAATTTT TCTCTAGGAAGGCGTAGAATTTTAAAGAACTGGTAATAGGAAAGCATGTACTATTTTCTTAAAGCAATAAACTCTTGAATGAACAGATTG CGATTTACTTTCAGACATAATTTGGAGATGGCAGTAGATCAAAATGTGTCCATGACTTGTTAACATGCCTTTCTTTCTTCCTCCTTAGCC AAAATCCACCTTTGAACTACAAAGACAGAGCAAGGCGTTCATTTTGGTGGGAGGAAGCATTGGTTCAGAGTGTTAGTGACTAGTATCGCC ATGCCGTCACTTAAATGCTTTCAGGCTTGCATGCTTGTGGCTCCAATGGCGCACACTCAGGAAGGAATTGTAAAGGAGCACCCAGTTATA TTATAAAGCCTGGATGTATGGTTTGCAGATAATGGAAATCCTGTGGATTTTCACTGATCCAGTCTATCTTTACCAATAGTATCTCTCTCT TCTCCCTTATGTTATTAGAGAACCTGATATTGGCTATTCCAAAGATTAAATTATTTTCAAATAGTTTTCAACAAAAATAAAAGTGTATTA GGAAGAAAAAAGTAGACTATATGAAGAGTTTGTGACTGCTCAATTTAACTTGTTTTTTGCCTTATTTCTATTAAGACTGTTTTACTATGT TTTTGCCCTAGGGATATCAGCAAATATTTATTTTTCCTAGCATGATATAGTTAGAATTTCAAGCAGATTTCTTTGTAATTAGAAGGCATC TGATAGAAATTGTAAAACTTTAGAAGTTATTATAATGAAACCAATTCCTGAATCACAACTTCATGGACTGACTAAATTGATTTATAGTTG CCTTGTGAGGTATGTATGGGGAAAACATAAAAACATAATTAAAACATAATTTCGTCCTTTTTATGAATTCTTAAGAGATGTTCTTCCATA AATATAGAAATAATATATTTTTCTTAAAGGATATATTTTTAATTATGTGGAAGTTGTAAGCTTGAAATTTTAACTTCTAGTGCTTTTCTA AAATTCACAATTACAAGTTTAAAACATTTTTTCTCTTCCAGGTTTCATTTGGAATAAAGAGTTGGCAGTTATATAAAGCACTTAATAATA CTATAGAAAATAGATGTGTTTTTTCTTAATATGATTTTGGTATTTTCCACAGATCAGAAGTGTAAACAGAGAGATAATGTAACAGTATTT GGAAGAGATAATGACACAAGGATATAGTGATCTGGGAGCATGAATTAGAAACAGGGTACTATGTTTCTGGTGTAAAATCTAAATTGTGCT TTCTACTAGCGTTACTTTTTCAAATGGGATGATATAAAGCACTGTGGGCTATAAGCAACAATCTTGGGTTGGTAGGCAAATAGACCAATT GATCTTTATTATTATTATTATTATTATTATTATTATTTTTTGAGATGAAGTCTTGCTCTTGTCGCCCAGGCTGGGTGCAGTGGCATGATC TTGGCTTACTGCAACCTCTGCCTCCTGGGTTCAAGCACCTGAGCCTCCCGAGTAGCTGGGATTACAGGCATCTGCCACCACACCTGGCTA ATTTTTGTATTTTTTGTAGAGACAGATGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCGCCCGCCTTTGC ATCCCAAAATGCTGGGATTACAGGTGTGAGCCACAGCACCCGGTCCCAGTTGGTCTTTTAATATTAAATTTGTGCACTATTACTGGGTCT GGAGTTAATGATTTCAAATAGTTTCTAAAAATAACTGATTAAATGTAAGAAATTATAACTAATTATCAAGGTGATTCTCTTTTGTTTCTT CAATGGAGAGTTTCTCTTTCTCTTTTCCTCCTCTAATAAAAATATTTCTTTTTTTCCTGTCCTTTTATTCATTATATTATGAAACTTAGG TTTTAGGAAACACCTTAAGCGTCATTTTAATGAAGCACAACATTGATATTTTACATGAATAATAACGTTTGGTATTTTAAATATACTTCA AGGGGGTAATAAGCCACAATAACTGTACCAAAAAAACTTAAAAATGGGGACATATTCATCCCTTGTGTGTGCATATTTTACCACTTGTTG ACAAGATACAATTGTGACCTACTTTGAGGGGATGAATAACGACTTATCACTTTAAGACACTTTGCAAACATGTTACTAAAAAAAGGTGCC TAGCCAAGGAAAAAACCATTCACTTGGAATTAAAATTGTGGATGTCACTTCAGAGATGACTTTAACATAAATGCTGAAAGTTCATTCACC TCACAAATGTGGCAGTTTTCTCTGTGGAGAATGGTGGTCTCCGTGGCAGACTGGCTCTCCAAATTAAATGAAACTCATTGACAGACCTGG GACCTTTTATGTGAGTGGACAGACAAGATCTTGGTTTGGCTTCATGTACTGTTTTCTAGAGAGAGTGCTACGAAAAACTTATGATGCTTT TATGTGATAACCAATATAATGCTTTAATATGTTAATTCTTTGTGATGCTATATACATAGTTTTTATAGTTTTATGAAACCACTTTGTTAA ACTTATCTGGATTTTAAGACACTTGTAAACAAATGGTTTGTTAGTAAAATTGGGGCATTAAGAGTTTTACAGAGCAAATAAAGAAGATTT >3916_3916_3_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000357578_DCDC2_chr6_24178860_ENST00000378450_length(amino acids)=299AA_BP=164 MQPSASSHAFPARPRRLLAPLASPRPLRSRARAPACLFPVAVVARAMATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQL RCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKRPAEIVDEEEDGEKAN KDAEQKEDFSGMNGDLEEEGGREATDAPEQVEEILDHSEQQARPARVNGGTDEENGEELQQVNNELQLVLDKERKSQGAGSGQDEADVDP -------------------------------------------------------------- >3916_3916_4_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000357578_DCDC2_chr6_24178860_ENST00000378454_length(transcript)=3881nt_BP=499nt TGTGGCTCTGCAACCTTCCGCCAGCTCCCACGCTTTCCCCGCGCGTCCCCGGCGCCTCCTCGCTCCTCTTGCTTCCCCGCGACCCCTGCG TTCCCGTGCGCGCGCGCCCGCTTGCCTGTTTCCTGTCGCCGTCGTTGCCCGGGCCATGGCGACCTGCATTTGGCTGCGGAGCTGTGGGGC CCGGCGCCTCGGGTCGACGTTTCCAGGCTGCCGCCTCCGCCCCCGCGCCGGCGGCCTGGTCCCTGCCTCCGGGCCTGCGCCCGGCCCGGC CCAGCTCCGCTGCTACGCTGGGCGCCTGGCGGGCCTCTCTGCGGCGCTGCTGCGCACCGACAGCTTCGTGGGCGGCCGCTGGCTCCCGGC CGCCGCCACCTTCCCCGTGCAAGACCCGGCCAGCGGCGCCGCTCTGGGCATGGTAGCCGACTGCGGGGTGCGAGAGGCCCGCGCCGCCGT GCGCGCTGCCTACGAGGCTTTCTGCCGCTGGAGGGAGGTCTCCGCCAAGAGGCCAGCAGAAATAGTAGACGAGGAAGAAGATGGAGAGAA GGCAAACAAGGATGCAGAACAGAAAGAAGACTTTTCAGGAATGAATGGTGACCTTGAAGAGGAAGGAGGTAGGGAGGCTACAGATGCCCC TGAGCAAGTCGAGGAGATTCTGGATCACAGTGAGCAGCAGGCACGCCCTGCTCGTGTAAATGGAGGCACCGATGAGGAGAATGGTGAGGA GCTGCAGCAGGTTAATAATGAGCTTCAACTGGTCCTAGACAAGGAAAGAAAGTCTCAAGGAGCTGGCAGTGGACAAGATGAGGCTGATGT AGACCCTCAAAGACCACCAAGGCCAGAAGTAAAAATTACCAGTCCAGAAGAAAATGAAAACAACCAACAAAACAAGGACTATGCTGCCGT GGCTTAGAACATTTTTAAAAAGAGAGTATATGGATCGCAAGAAAAATGAAGGGTTATCATACTTGAAAGATAAGCACATAGTTATTGCTG AATATAATGTGACACTATGGTCGAATACTACCTACGAATTATAACATTAGAAGCCTAGTGGAAAGACCAGATAACTTTAAATGGCTACTA AAGGATAATTACTTACTTTTATTGCATGTGTTTTAAAAGTCATATAGAAATATTAAATAAGACGGACAGAGGAGAATTTGCACTGGAAGA CAATTGCCACTTGTAAAGGATGAAAAATAGGATCACTCTTATTGTACGCTTTATTATAAGTTTAGAAGGCAGTTTATTCTAAATAATTTT TCTCTAGGAAGGCGTAGAATTTTAAAGAACTGGTAATAGGAAAGCATGTACTATTTTCTTAAAGCAATAAACTCTTGAATGAACAGATTG CGATTTACTTTCAGACATAATTTGGAGATGGCAGTAGATCAAAATGTGTCCATGACTTGTTAACATGCCTTTCTTTCTTCCTCCTTAGCC AAAATCCACCTTTGAACTACAAAGACAGAGCAAGGCGTTCATTTTGGTGGGAGGAAGCATTGGTTCAGAGTGTTAGTGACTAGTATCGCC ATGCCGTCACTTAAATGCTTTCAGGCTTGCATGCTTGTGGCTCCAATGGCGCACACTCAGGAAGGAATTGTAAAGGAGCACCCAGTTATA TTATAAAGCCTGGATGTATGGTTTGCAGATAATGGAAATCCTGTGGATTTTCACTGATCCAGTCTATCTTTACCAATAGTATCTCTCTCT TCTCCCTTATGTTATTAGAGAACCTGATATTGGCTATTCCAAAGATTAAATTATTTTCAAATAGTTTTCAACAAAAATAAAAGTGTATTA GGAAGAAAAAAGTAGACTATATGAAGAGTTTGTGACTGCTCAATTTAACTTGTTTTTTGCCTTATTTCTATTAAGACTGTTTTACTATGT TTTTGCCCTAGGGATATCAGCAAATATTTATTTTTCCTAGCATGATATAGTTAGAATTTCAAGCAGATTTCTTTGTAATTAGAAGGCATC TGATAGAAATTGTAAAACTTTAGAAGTTATTATAATGAAACCAATTCCTGAATCACAACTTCATGGACTGACTAAATTGATTTATAGTTG CCTTGTGAGGTATGTATGGGGAAAACATAAAAACATAATTAAAACATAATTTCGTCCTTTTTATGAATTCTTAAGAGATGTTCTTCCATA AATATAGAAATAATATATTTTTCTTAAAGGATATATTTTTAATTATGTGGAAGTTGTAAGCTTGAAATTTTAACTTCTAGTGCTTTTCTA AAATTCACAATTACAAGTTTAAAACATTTTTTCTCTTCCAGGTTTCATTTGGAATAAAGAGTTGGCAGTTATATAAAGCACTTAATAATA CTATAGAAAATAGATGTGTTTTTTCTTAATATGATTTTGGTATTTTCCACAGATCAGAAGTGTAAACAGAGAGATAATGTAACAGTATTT GGAAGAGATAATGACACAAGGATATAGTGATCTGGGAGCATGAATTAGAAACAGGGTACTATGTTTCTGGTGTAAAATCTAAATTGTGCT TTCTACTAGCGTTACTTTTTCAAATGGGATGATATAAAGCACTGTGGGCTATAAGCAACAATCTTGGGTTGGTAGGCAAATAGACCAATT GATCTTTATTATTATTATTATTATTATTATTATTATTTTTTGAGATGAAGTCTTGCTCTTGTCGCCCAGGCTGGGTGCAGTGGCATGATC TTGGCTTACTGCAACCTCTGCCTCCTGGGTTCAAGCACCTGAGCCTCCCGAGTAGCTGGGATTACAGGCATCTGCCACCACACCTGGCTA ATTTTTGTATTTTTTGTAGAGACAGATGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCGCCCGCCTTTGC ATCCCAAAATGCTGGGATTACAGGTGTGAGCCACAGCACCCGGTCCCAGTTGGTCTTTTAATATTAAATTTGTGCACTATTACTGGGTCT GGAGTTAATGATTTCAAATAGTTTCTAAAAATAACTGATTAAATGTAAGAAATTATAACTAATTATCAAGGTGATTCTCTTTTGTTTCTT CAATGGAGAGTTTCTCTTTCTCTTTTCCTCCTCTAATAAAAATATTTCTTTTTTTCCTGTCCTTTTATTCATTATATTATGAAACTTAGG TTTTAGGAAACACCTTAAGCGTCATTTTAATGAAGCACAACATTGATATTTTACATGAATAATAACGTTTGGTATTTTAAATATACTTCA AGGGGGTAATAAGCCACAATAACTGTACCAAAAAAACTTAAAAATGGGGACATATTCATCCCTTGTGTGTGCATATTTTACCACTTGTTG ACAAGATACAATTGTGACCTACTTTGAGGGGATGAATAACGACTTATCACTTTAAGACACTTTGCAAACATGTTACTAAAAAAAGGTGCC TAGCCAAGGAAAAAACCATTCACTTGGAATTAAAATTGTGGATGTCACTTCAGAGATGACTTTAACATAAATGCTGAAAGTTCATTCACC TCACAAATGTGGCAGTTTTCTCTGTGGAGAATGGTGGTCTCCGTGGCAGACTGGCTCTCCAAATTAAATGAAACTCATTGACAGACCTGG GACCTTTTATGTGAGTGGACAGACAAGATCTTGGTTTGGCTTCATGTACTGTTTTCTAGAGAGAGTGCTACGAAAAACTTATGATGCTTT TATGTGATAACCAATATAATGCTTTAATATGTTAATTCTTTGTGATGCTATATACATAGTTTTTATAGTTTTATGAAACCACTTTGTTAA ACTTATCTGGATTTTAAGACACTTGTAAACAAATGGTTTGTTAGTAAAATTGGGGCATTAAGAGTTTTACAGAGCAAATAAAGAAGATTT >3916_3916_4_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000357578_DCDC2_chr6_24178860_ENST00000378454_length(amino acids)=299AA_BP=164 MQPSASSHAFPARPRRLLAPLASPRPLRSRARAPACLFPVAVVARAMATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQL RCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKRPAEIVDEEEDGEKAN KDAEQKEDFSGMNGDLEEEGGREATDAPEQVEEILDHSEQQARPARVNGGTDEENGEELQQVNNELQLVLDKERKSQGAGSGQDEADVDP -------------------------------------------------------------- >3916_3916_5_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000491546_DCDC2_chr6_24178860_ENST00000378450_length(transcript)=3866nt_BP=484nt TTCCGCCAGCTCCCACGCTTTCCCCGCGCGTCCCCGGCGCCTCCTCGCTCCTCTTGCTTCCCCGCGACCCCTGCGTTCCCGTGCGCGCGC GCCCGCTTGCCTGTTTCCTGTCGCCGTCGTTGCCCGGGCCATGGCGACCTGCATTTGGCTGCGGAGCTGTGGGGCCCGGCGCCTCGGGTC GACGTTTCCAGGCTGCCGCCTCCGCCCCCGCGCCGGCGGCCTGGTCCCTGCCTCCGGGCCTGCGCCCGGCCCGGCCCAGCTCCGCTGCTA CGCTGGGCGCCTGGCGGGCCTCTCTGCGGCGCTGCTGCGCACCGACAGCTTCGTGGGCGGCCGCTGGCTCCCGGCCGCCGCCACCTTCCC CGTGCAAGACCCGGCCAGCGGCGCCGCTCTGGGCATGGTAGCCGACTGCGGGGTGCGAGAGGCCCGCGCCGCCGTGCGCGCTGCCTACGA GGCTTTCTGCCGCTGGAGGGAGGTCTCCGCCAAGAGGCCAGCAGAAATAGTAGACGAGGAAGAAGATGGAGAGAAGGCAAACAAGGATGC AGAACAGAAAGAAGACTTTTCAGGAATGAATGGTGACCTTGAAGAGGAAGGAGGTAGGGAGGCTACAGATGCCCCTGAGCAAGTCGAGGA GATTCTGGATCACAGTGAGCAGCAGGCACGCCCTGCTCGTGTAAATGGAGGCACCGATGAGGAGAATGGTGAGGAGCTGCAGCAGGTTAA TAATGAGCTTCAACTGGTCCTAGACAAGGAAAGAAAGTCTCAAGGAGCTGGCAGTGGACAAGATGAGGCTGATGTAGACCCTCAAAGACC ACCAAGGCCAGAAGTAAAAATTACCAGTCCAGAAGAAAATGAAAACAACCAACAAAACAAGGACTATGCTGCCGTGGCTTAGAACATTTT TAAAAAGAGAGTATATGGATCGCAAGAAAAATGAAGGGTTATCATACTTGAAAGATAAGCACATAGTTATTGCTGAATATAATGTGACAC TATGGTCGAATACTACCTACGAATTATAACATTAGAAGCCTAGTGGAAAGACCAGATAACTTTAAATGGCTACTAAAGGATAATTACTTA CTTTTATTGCATGTGTTTTAAAAGTCATATAGAAATATTAAATAAGACGGACAGAGGAGAATTTGCACTGGAAGACAATTGCCACTTGTA AAGGATGAAAAATAGGATCACTCTTATTGTACGCTTTATTATAAGTTTAGAAGGCAGTTTATTCTAAATAATTTTTCTCTAGGAAGGCGT AGAATTTTAAAGAACTGGTAATAGGAAAGCATGTACTATTTTCTTAAAGCAATAAACTCTTGAATGAACAGATTGCGATTTACTTTCAGA CATAATTTGGAGATGGCAGTAGATCAAAATGTGTCCATGACTTGTTAACATGCCTTTCTTTCTTCCTCCTTAGCCAAAATCCACCTTTGA ACTACAAAGACAGAGCAAGGCGTTCATTTTGGTGGGAGGAAGCATTGGTTCAGAGTGTTAGTGACTAGTATCGCCATGCCGTCACTTAAA TGCTTTCAGGCTTGCATGCTTGTGGCTCCAATGGCGCACACTCAGGAAGGAATTGTAAAGGAGCACCCAGTTATATTATAAAGCCTGGAT GTATGGTTTGCAGATAATGGAAATCCTGTGGATTTTCACTGATCCAGTCTATCTTTACCAATAGTATCTCTCTCTTCTCCCTTATGTTAT TAGAGAACCTGATATTGGCTATTCCAAAGATTAAATTATTTTCAAATAGTTTTCAACAAAAATAAAAGTGTATTAGGAAGAAAAAAGTAG ACTATATGAAGAGTTTGTGACTGCTCAATTTAACTTGTTTTTTGCCTTATTTCTATTAAGACTGTTTTACTATGTTTTTGCCCTAGGGAT ATCAGCAAATATTTATTTTTCCTAGCATGATATAGTTAGAATTTCAAGCAGATTTCTTTGTAATTAGAAGGCATCTGATAGAAATTGTAA AACTTTAGAAGTTATTATAATGAAACCAATTCCTGAATCACAACTTCATGGACTGACTAAATTGATTTATAGTTGCCTTGTGAGGTATGT ATGGGGAAAACATAAAAACATAATTAAAACATAATTTCGTCCTTTTTATGAATTCTTAAGAGATGTTCTTCCATAAATATAGAAATAATA TATTTTTCTTAAAGGATATATTTTTAATTATGTGGAAGTTGTAAGCTTGAAATTTTAACTTCTAGTGCTTTTCTAAAATTCACAATTACA AGTTTAAAACATTTTTTCTCTTCCAGGTTTCATTTGGAATAAAGAGTTGGCAGTTATATAAAGCACTTAATAATACTATAGAAAATAGAT GTGTTTTTTCTTAATATGATTTTGGTATTTTCCACAGATCAGAAGTGTAAACAGAGAGATAATGTAACAGTATTTGGAAGAGATAATGAC ACAAGGATATAGTGATCTGGGAGCATGAATTAGAAACAGGGTACTATGTTTCTGGTGTAAAATCTAAATTGTGCTTTCTACTAGCGTTAC TTTTTCAAATGGGATGATATAAAGCACTGTGGGCTATAAGCAACAATCTTGGGTTGGTAGGCAAATAGACCAATTGATCTTTATTATTAT TATTATTATTATTATTATTATTTTTTGAGATGAAGTCTTGCTCTTGTCGCCCAGGCTGGGTGCAGTGGCATGATCTTGGCTTACTGCAAC CTCTGCCTCCTGGGTTCAAGCACCTGAGCCTCCCGAGTAGCTGGGATTACAGGCATCTGCCACCACACCTGGCTAATTTTTGTATTTTTT GTAGAGACAGATGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCGCCCGCCTTTGCATCCCAAAATGCTGG GATTACAGGTGTGAGCCACAGCACCCGGTCCCAGTTGGTCTTTTAATATTAAATTTGTGCACTATTACTGGGTCTGGAGTTAATGATTTC AAATAGTTTCTAAAAATAACTGATTAAATGTAAGAAATTATAACTAATTATCAAGGTGATTCTCTTTTGTTTCTTCAATGGAGAGTTTCT CTTTCTCTTTTCCTCCTCTAATAAAAATATTTCTTTTTTTCCTGTCCTTTTATTCATTATATTATGAAACTTAGGTTTTAGGAAACACCT TAAGCGTCATTTTAATGAAGCACAACATTGATATTTTACATGAATAATAACGTTTGGTATTTTAAATATACTTCAAGGGGGTAATAAGCC ACAATAACTGTACCAAAAAAACTTAAAAATGGGGACATATTCATCCCTTGTGTGTGCATATTTTACCACTTGTTGACAAGATACAATTGT GACCTACTTTGAGGGGATGAATAACGACTTATCACTTTAAGACACTTTGCAAACATGTTACTAAAAAAAGGTGCCTAGCCAAGGAAAAAA CCATTCACTTGGAATTAAAATTGTGGATGTCACTTCAGAGATGACTTTAACATAAATGCTGAAAGTTCATTCACCTCACAAATGTGGCAG TTTTCTCTGTGGAGAATGGTGGTCTCCGTGGCAGACTGGCTCTCCAAATTAAATGAAACTCATTGACAGACCTGGGACCTTTTATGTGAG TGGACAGACAAGATCTTGGTTTGGCTTCATGTACTGTTTTCTAGAGAGAGTGCTACGAAAAACTTATGATGCTTTTATGTGATAACCAAT ATAATGCTTTAATATGTTAATTCTTTGTGATGCTATATACATAGTTTTTATAGTTTTATGAAACCACTTTGTTAAACTTATCTGGATTTT >3916_3916_5_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000491546_DCDC2_chr6_24178860_ENST00000378450_length(amino acids)=273AA_BP=138 MRSRARAPACLFPVAVVARAMATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWL PAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGREATD APEQVEEILDHSEQQARPARVNGGTDEENGEELQQVNNELQLVLDKERKSQGAGSGQDEADVDPQRPPRPEVKITSPEENENNQQNKDYA -------------------------------------------------------------- >3916_3916_6_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000491546_DCDC2_chr6_24178860_ENST00000378454_length(transcript)=3866nt_BP=484nt TTCCGCCAGCTCCCACGCTTTCCCCGCGCGTCCCCGGCGCCTCCTCGCTCCTCTTGCTTCCCCGCGACCCCTGCGTTCCCGTGCGCGCGC GCCCGCTTGCCTGTTTCCTGTCGCCGTCGTTGCCCGGGCCATGGCGACCTGCATTTGGCTGCGGAGCTGTGGGGCCCGGCGCCTCGGGTC GACGTTTCCAGGCTGCCGCCTCCGCCCCCGCGCCGGCGGCCTGGTCCCTGCCTCCGGGCCTGCGCCCGGCCCGGCCCAGCTCCGCTGCTA CGCTGGGCGCCTGGCGGGCCTCTCTGCGGCGCTGCTGCGCACCGACAGCTTCGTGGGCGGCCGCTGGCTCCCGGCCGCCGCCACCTTCCC CGTGCAAGACCCGGCCAGCGGCGCCGCTCTGGGCATGGTAGCCGACTGCGGGGTGCGAGAGGCCCGCGCCGCCGTGCGCGCTGCCTACGA GGCTTTCTGCCGCTGGAGGGAGGTCTCCGCCAAGAGGCCAGCAGAAATAGTAGACGAGGAAGAAGATGGAGAGAAGGCAAACAAGGATGC AGAACAGAAAGAAGACTTTTCAGGAATGAATGGTGACCTTGAAGAGGAAGGAGGTAGGGAGGCTACAGATGCCCCTGAGCAAGTCGAGGA GATTCTGGATCACAGTGAGCAGCAGGCACGCCCTGCTCGTGTAAATGGAGGCACCGATGAGGAGAATGGTGAGGAGCTGCAGCAGGTTAA TAATGAGCTTCAACTGGTCCTAGACAAGGAAAGAAAGTCTCAAGGAGCTGGCAGTGGACAAGATGAGGCTGATGTAGACCCTCAAAGACC ACCAAGGCCAGAAGTAAAAATTACCAGTCCAGAAGAAAATGAAAACAACCAACAAAACAAGGACTATGCTGCCGTGGCTTAGAACATTTT TAAAAAGAGAGTATATGGATCGCAAGAAAAATGAAGGGTTATCATACTTGAAAGATAAGCACATAGTTATTGCTGAATATAATGTGACAC TATGGTCGAATACTACCTACGAATTATAACATTAGAAGCCTAGTGGAAAGACCAGATAACTTTAAATGGCTACTAAAGGATAATTACTTA CTTTTATTGCATGTGTTTTAAAAGTCATATAGAAATATTAAATAAGACGGACAGAGGAGAATTTGCACTGGAAGACAATTGCCACTTGTA AAGGATGAAAAATAGGATCACTCTTATTGTACGCTTTATTATAAGTTTAGAAGGCAGTTTATTCTAAATAATTTTTCTCTAGGAAGGCGT AGAATTTTAAAGAACTGGTAATAGGAAAGCATGTACTATTTTCTTAAAGCAATAAACTCTTGAATGAACAGATTGCGATTTACTTTCAGA CATAATTTGGAGATGGCAGTAGATCAAAATGTGTCCATGACTTGTTAACATGCCTTTCTTTCTTCCTCCTTAGCCAAAATCCACCTTTGA ACTACAAAGACAGAGCAAGGCGTTCATTTTGGTGGGAGGAAGCATTGGTTCAGAGTGTTAGTGACTAGTATCGCCATGCCGTCACTTAAA TGCTTTCAGGCTTGCATGCTTGTGGCTCCAATGGCGCACACTCAGGAAGGAATTGTAAAGGAGCACCCAGTTATATTATAAAGCCTGGAT GTATGGTTTGCAGATAATGGAAATCCTGTGGATTTTCACTGATCCAGTCTATCTTTACCAATAGTATCTCTCTCTTCTCCCTTATGTTAT TAGAGAACCTGATATTGGCTATTCCAAAGATTAAATTATTTTCAAATAGTTTTCAACAAAAATAAAAGTGTATTAGGAAGAAAAAAGTAG ACTATATGAAGAGTTTGTGACTGCTCAATTTAACTTGTTTTTTGCCTTATTTCTATTAAGACTGTTTTACTATGTTTTTGCCCTAGGGAT ATCAGCAAATATTTATTTTTCCTAGCATGATATAGTTAGAATTTCAAGCAGATTTCTTTGTAATTAGAAGGCATCTGATAGAAATTGTAA AACTTTAGAAGTTATTATAATGAAACCAATTCCTGAATCACAACTTCATGGACTGACTAAATTGATTTATAGTTGCCTTGTGAGGTATGT ATGGGGAAAACATAAAAACATAATTAAAACATAATTTCGTCCTTTTTATGAATTCTTAAGAGATGTTCTTCCATAAATATAGAAATAATA TATTTTTCTTAAAGGATATATTTTTAATTATGTGGAAGTTGTAAGCTTGAAATTTTAACTTCTAGTGCTTTTCTAAAATTCACAATTACA AGTTTAAAACATTTTTTCTCTTCCAGGTTTCATTTGGAATAAAGAGTTGGCAGTTATATAAAGCACTTAATAATACTATAGAAAATAGAT GTGTTTTTTCTTAATATGATTTTGGTATTTTCCACAGATCAGAAGTGTAAACAGAGAGATAATGTAACAGTATTTGGAAGAGATAATGAC ACAAGGATATAGTGATCTGGGAGCATGAATTAGAAACAGGGTACTATGTTTCTGGTGTAAAATCTAAATTGTGCTTTCTACTAGCGTTAC TTTTTCAAATGGGATGATATAAAGCACTGTGGGCTATAAGCAACAATCTTGGGTTGGTAGGCAAATAGACCAATTGATCTTTATTATTAT TATTATTATTATTATTATTATTTTTTGAGATGAAGTCTTGCTCTTGTCGCCCAGGCTGGGTGCAGTGGCATGATCTTGGCTTACTGCAAC CTCTGCCTCCTGGGTTCAAGCACCTGAGCCTCCCGAGTAGCTGGGATTACAGGCATCTGCCACCACACCTGGCTAATTTTTGTATTTTTT GTAGAGACAGATGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCGCCCGCCTTTGCATCCCAAAATGCTGG GATTACAGGTGTGAGCCACAGCACCCGGTCCCAGTTGGTCTTTTAATATTAAATTTGTGCACTATTACTGGGTCTGGAGTTAATGATTTC AAATAGTTTCTAAAAATAACTGATTAAATGTAAGAAATTATAACTAATTATCAAGGTGATTCTCTTTTGTTTCTTCAATGGAGAGTTTCT CTTTCTCTTTTCCTCCTCTAATAAAAATATTTCTTTTTTTCCTGTCCTTTTATTCATTATATTATGAAACTTAGGTTTTAGGAAACACCT TAAGCGTCATTTTAATGAAGCACAACATTGATATTTTACATGAATAATAACGTTTGGTATTTTAAATATACTTCAAGGGGGTAATAAGCC ACAATAACTGTACCAAAAAAACTTAAAAATGGGGACATATTCATCCCTTGTGTGTGCATATTTTACCACTTGTTGACAAGATACAATTGT GACCTACTTTGAGGGGATGAATAACGACTTATCACTTTAAGACACTTTGCAAACATGTTACTAAAAAAAGGTGCCTAGCCAAGGAAAAAA CCATTCACTTGGAATTAAAATTGTGGATGTCACTTCAGAGATGACTTTAACATAAATGCTGAAAGTTCATTCACCTCACAAATGTGGCAG TTTTCTCTGTGGAGAATGGTGGTCTCCGTGGCAGACTGGCTCTCCAAATTAAATGAAACTCATTGACAGACCTGGGACCTTTTATGTGAG TGGACAGACAAGATCTTGGTTTGGCTTCATGTACTGTTTTCTAGAGAGAGTGCTACGAAAAACTTATGATGCTTTTATGTGATAACCAAT ATAATGCTTTAATATGTTAATTCTTTGTGATGCTATATACATAGTTTTTATAGTTTTATGAAACCACTTTGTTAAACTTATCTGGATTTT >3916_3916_6_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000491546_DCDC2_chr6_24178860_ENST00000378454_length(amino acids)=273AA_BP=138 MRSRARAPACLFPVAVVARAMATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWL PAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGREATD APEQVEEILDHSEQQARPARVNGGTDEENGEELQQVNNELQLVLDKERKSQGAGSGQDEADVDPQRPPRPEVKITSPEENENNQQNKDYA -------------------------------------------------------------- >3916_3916_7_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000546278_DCDC2_chr6_24178860_ENST00000378450_length(transcript)=3539nt_BP=157nt TGTGGCTCTGCAACCTTCCGCCAGCTCCCACGCTTTCCCCGCGCGTCCCCGCGGCGCCGCTCTGGGCATGGTAGCCGACTGCGGGGTGCG AGAGGCCCGCGCCGCCGTGCGCGCTGCCTACGAGGCTTTCTGCCGCTGGAGGGAGGTCTCCGCCAAGAGGCCAGCAGAAATAGTAGACGA GGAAGAAGATGGAGAGAAGGCAAACAAGGATGCAGAACAGAAAGAAGACTTTTCAGGAATGAATGGTGACCTTGAAGAGGAAGGAGGTAG GGAGGCTACAGATGCCCCTGAGCAAGTCGAGGAGATTCTGGATCACAGTGAGCAGCAGGCACGCCCTGCTCGTGTAAATGGAGGCACCGA TGAGGAGAATGGTGAGGAGCTGCAGCAGGTTAATAATGAGCTTCAACTGGTCCTAGACAAGGAAAGAAAGTCTCAAGGAGCTGGCAGTGG ACAAGATGAGGCTGATGTAGACCCTCAAAGACCACCAAGGCCAGAAGTAAAAATTACCAGTCCAGAAGAAAATGAAAACAACCAACAAAA CAAGGACTATGCTGCCGTGGCTTAGAACATTTTTAAAAAGAGAGTATATGGATCGCAAGAAAAATGAAGGGTTATCATACTTGAAAGATA AGCACATAGTTATTGCTGAATATAATGTGACACTATGGTCGAATACTACCTACGAATTATAACATTAGAAGCCTAGTGGAAAGACCAGAT AACTTTAAATGGCTACTAAAGGATAATTACTTACTTTTATTGCATGTGTTTTAAAAGTCATATAGAAATATTAAATAAGACGGACAGAGG AGAATTTGCACTGGAAGACAATTGCCACTTGTAAAGGATGAAAAATAGGATCACTCTTATTGTACGCTTTATTATAAGTTTAGAAGGCAG TTTATTCTAAATAATTTTTCTCTAGGAAGGCGTAGAATTTTAAAGAACTGGTAATAGGAAAGCATGTACTATTTTCTTAAAGCAATAAAC TCTTGAATGAACAGATTGCGATTTACTTTCAGACATAATTTGGAGATGGCAGTAGATCAAAATGTGTCCATGACTTGTTAACATGCCTTT CTTTCTTCCTCCTTAGCCAAAATCCACCTTTGAACTACAAAGACAGAGCAAGGCGTTCATTTTGGTGGGAGGAAGCATTGGTTCAGAGTG TTAGTGACTAGTATCGCCATGCCGTCACTTAAATGCTTTCAGGCTTGCATGCTTGTGGCTCCAATGGCGCACACTCAGGAAGGAATTGTA AAGGAGCACCCAGTTATATTATAAAGCCTGGATGTATGGTTTGCAGATAATGGAAATCCTGTGGATTTTCACTGATCCAGTCTATCTTTA CCAATAGTATCTCTCTCTTCTCCCTTATGTTATTAGAGAACCTGATATTGGCTATTCCAAAGATTAAATTATTTTCAAATAGTTTTCAAC AAAAATAAAAGTGTATTAGGAAGAAAAAAGTAGACTATATGAAGAGTTTGTGACTGCTCAATTTAACTTGTTTTTTGCCTTATTTCTATT AAGACTGTTTTACTATGTTTTTGCCCTAGGGATATCAGCAAATATTTATTTTTCCTAGCATGATATAGTTAGAATTTCAAGCAGATTTCT TTGTAATTAGAAGGCATCTGATAGAAATTGTAAAACTTTAGAAGTTATTATAATGAAACCAATTCCTGAATCACAACTTCATGGACTGAC TAAATTGATTTATAGTTGCCTTGTGAGGTATGTATGGGGAAAACATAAAAACATAATTAAAACATAATTTCGTCCTTTTTATGAATTCTT AAGAGATGTTCTTCCATAAATATAGAAATAATATATTTTTCTTAAAGGATATATTTTTAATTATGTGGAAGTTGTAAGCTTGAAATTTTA ACTTCTAGTGCTTTTCTAAAATTCACAATTACAAGTTTAAAACATTTTTTCTCTTCCAGGTTTCATTTGGAATAAAGAGTTGGCAGTTAT ATAAAGCACTTAATAATACTATAGAAAATAGATGTGTTTTTTCTTAATATGATTTTGGTATTTTCCACAGATCAGAAGTGTAAACAGAGA GATAATGTAACAGTATTTGGAAGAGATAATGACACAAGGATATAGTGATCTGGGAGCATGAATTAGAAACAGGGTACTATGTTTCTGGTG TAAAATCTAAATTGTGCTTTCTACTAGCGTTACTTTTTCAAATGGGATGATATAAAGCACTGTGGGCTATAAGCAACAATCTTGGGTTGG TAGGCAAATAGACCAATTGATCTTTATTATTATTATTATTATTATTATTATTATTTTTTGAGATGAAGTCTTGCTCTTGTCGCCCAGGCT GGGTGCAGTGGCATGATCTTGGCTTACTGCAACCTCTGCCTCCTGGGTTCAAGCACCTGAGCCTCCCGAGTAGCTGGGATTACAGGCATC TGCCACCACACCTGGCTAATTTTTGTATTTTTTGTAGAGACAGATGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGG TGATCCGCCCGCCTTTGCATCCCAAAATGCTGGGATTACAGGTGTGAGCCACAGCACCCGGTCCCAGTTGGTCTTTTAATATTAAATTTG TGCACTATTACTGGGTCTGGAGTTAATGATTTCAAATAGTTTCTAAAAATAACTGATTAAATGTAAGAAATTATAACTAATTATCAAGGT GATTCTCTTTTGTTTCTTCAATGGAGAGTTTCTCTTTCTCTTTTCCTCCTCTAATAAAAATATTTCTTTTTTTCCTGTCCTTTTATTCAT TATATTATGAAACTTAGGTTTTAGGAAACACCTTAAGCGTCATTTTAATGAAGCACAACATTGATATTTTACATGAATAATAACGTTTGG TATTTTAAATATACTTCAAGGGGGTAATAAGCCACAATAACTGTACCAAAAAAACTTAAAAATGGGGACATATTCATCCCTTGTGTGTGC ATATTTTACCACTTGTTGACAAGATACAATTGTGACCTACTTTGAGGGGATGAATAACGACTTATCACTTTAAGACACTTTGCAAACATG TTACTAAAAAAAGGTGCCTAGCCAAGGAAAAAACCATTCACTTGGAATTAAAATTGTGGATGTCACTTCAGAGATGACTTTAACATAAAT GCTGAAAGTTCATTCACCTCACAAATGTGGCAGTTTTCTCTGTGGAGAATGGTGGTCTCCGTGGCAGACTGGCTCTCCAAATTAAATGAA ACTCATTGACAGACCTGGGACCTTTTATGTGAGTGGACAGACAAGATCTTGGTTTGGCTTCATGTACTGTTTTCTAGAGAGAGTGCTACG AAAAACTTATGATGCTTTTATGTGATAACCAATATAATGCTTTAATATGTTAATTCTTTGTGATGCTATATACATAGTTTTTATAGTTTT ATGAAACCACTTTGTTAAACTTATCTGGATTTTAAGACACTTGTAAACAAATGGTTTGTTAGTAAAATTGGGGCATTAAGAGTTTTACAG >3916_3916_7_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000546278_DCDC2_chr6_24178860_ENST00000378450_length(amino acids)=185AA_BP=50 MQPSASSHAFPARPRGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGREA TDAPEQVEEILDHSEQQARPARVNGGTDEENGEELQQVNNELQLVLDKERKSQGAGSGQDEADVDPQRPPRPEVKITSPEENENNQQNKD -------------------------------------------------------------- >3916_3916_8_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000546278_DCDC2_chr6_24178860_ENST00000378454_length(transcript)=3539nt_BP=157nt TGTGGCTCTGCAACCTTCCGCCAGCTCCCACGCTTTCCCCGCGCGTCCCCGCGGCGCCGCTCTGGGCATGGTAGCCGACTGCGGGGTGCG AGAGGCCCGCGCCGCCGTGCGCGCTGCCTACGAGGCTTTCTGCCGCTGGAGGGAGGTCTCCGCCAAGAGGCCAGCAGAAATAGTAGACGA GGAAGAAGATGGAGAGAAGGCAAACAAGGATGCAGAACAGAAAGAAGACTTTTCAGGAATGAATGGTGACCTTGAAGAGGAAGGAGGTAG GGAGGCTACAGATGCCCCTGAGCAAGTCGAGGAGATTCTGGATCACAGTGAGCAGCAGGCACGCCCTGCTCGTGTAAATGGAGGCACCGA TGAGGAGAATGGTGAGGAGCTGCAGCAGGTTAATAATGAGCTTCAACTGGTCCTAGACAAGGAAAGAAAGTCTCAAGGAGCTGGCAGTGG ACAAGATGAGGCTGATGTAGACCCTCAAAGACCACCAAGGCCAGAAGTAAAAATTACCAGTCCAGAAGAAAATGAAAACAACCAACAAAA CAAGGACTATGCTGCCGTGGCTTAGAACATTTTTAAAAAGAGAGTATATGGATCGCAAGAAAAATGAAGGGTTATCATACTTGAAAGATA AGCACATAGTTATTGCTGAATATAATGTGACACTATGGTCGAATACTACCTACGAATTATAACATTAGAAGCCTAGTGGAAAGACCAGAT AACTTTAAATGGCTACTAAAGGATAATTACTTACTTTTATTGCATGTGTTTTAAAAGTCATATAGAAATATTAAATAAGACGGACAGAGG AGAATTTGCACTGGAAGACAATTGCCACTTGTAAAGGATGAAAAATAGGATCACTCTTATTGTACGCTTTATTATAAGTTTAGAAGGCAG TTTATTCTAAATAATTTTTCTCTAGGAAGGCGTAGAATTTTAAAGAACTGGTAATAGGAAAGCATGTACTATTTTCTTAAAGCAATAAAC TCTTGAATGAACAGATTGCGATTTACTTTCAGACATAATTTGGAGATGGCAGTAGATCAAAATGTGTCCATGACTTGTTAACATGCCTTT CTTTCTTCCTCCTTAGCCAAAATCCACCTTTGAACTACAAAGACAGAGCAAGGCGTTCATTTTGGTGGGAGGAAGCATTGGTTCAGAGTG TTAGTGACTAGTATCGCCATGCCGTCACTTAAATGCTTTCAGGCTTGCATGCTTGTGGCTCCAATGGCGCACACTCAGGAAGGAATTGTA AAGGAGCACCCAGTTATATTATAAAGCCTGGATGTATGGTTTGCAGATAATGGAAATCCTGTGGATTTTCACTGATCCAGTCTATCTTTA CCAATAGTATCTCTCTCTTCTCCCTTATGTTATTAGAGAACCTGATATTGGCTATTCCAAAGATTAAATTATTTTCAAATAGTTTTCAAC AAAAATAAAAGTGTATTAGGAAGAAAAAAGTAGACTATATGAAGAGTTTGTGACTGCTCAATTTAACTTGTTTTTTGCCTTATTTCTATT AAGACTGTTTTACTATGTTTTTGCCCTAGGGATATCAGCAAATATTTATTTTTCCTAGCATGATATAGTTAGAATTTCAAGCAGATTTCT TTGTAATTAGAAGGCATCTGATAGAAATTGTAAAACTTTAGAAGTTATTATAATGAAACCAATTCCTGAATCACAACTTCATGGACTGAC TAAATTGATTTATAGTTGCCTTGTGAGGTATGTATGGGGAAAACATAAAAACATAATTAAAACATAATTTCGTCCTTTTTATGAATTCTT AAGAGATGTTCTTCCATAAATATAGAAATAATATATTTTTCTTAAAGGATATATTTTTAATTATGTGGAAGTTGTAAGCTTGAAATTTTA ACTTCTAGTGCTTTTCTAAAATTCACAATTACAAGTTTAAAACATTTTTTCTCTTCCAGGTTTCATTTGGAATAAAGAGTTGGCAGTTAT ATAAAGCACTTAATAATACTATAGAAAATAGATGTGTTTTTTCTTAATATGATTTTGGTATTTTCCACAGATCAGAAGTGTAAACAGAGA GATAATGTAACAGTATTTGGAAGAGATAATGACACAAGGATATAGTGATCTGGGAGCATGAATTAGAAACAGGGTACTATGTTTCTGGTG TAAAATCTAAATTGTGCTTTCTACTAGCGTTACTTTTTCAAATGGGATGATATAAAGCACTGTGGGCTATAAGCAACAATCTTGGGTTGG TAGGCAAATAGACCAATTGATCTTTATTATTATTATTATTATTATTATTATTATTTTTTGAGATGAAGTCTTGCTCTTGTCGCCCAGGCT GGGTGCAGTGGCATGATCTTGGCTTACTGCAACCTCTGCCTCCTGGGTTCAAGCACCTGAGCCTCCCGAGTAGCTGGGATTACAGGCATC TGCCACCACACCTGGCTAATTTTTGTATTTTTTGTAGAGACAGATGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGG TGATCCGCCCGCCTTTGCATCCCAAAATGCTGGGATTACAGGTGTGAGCCACAGCACCCGGTCCCAGTTGGTCTTTTAATATTAAATTTG TGCACTATTACTGGGTCTGGAGTTAATGATTTCAAATAGTTTCTAAAAATAACTGATTAAATGTAAGAAATTATAACTAATTATCAAGGT GATTCTCTTTTGTTTCTTCAATGGAGAGTTTCTCTTTCTCTTTTCCTCCTCTAATAAAAATATTTCTTTTTTTCCTGTCCTTTTATTCAT TATATTATGAAACTTAGGTTTTAGGAAACACCTTAAGCGTCATTTTAATGAAGCACAACATTGATATTTTACATGAATAATAACGTTTGG TATTTTAAATATACTTCAAGGGGGTAATAAGCCACAATAACTGTACCAAAAAAACTTAAAAATGGGGACATATTCATCCCTTGTGTGTGC ATATTTTACCACTTGTTGACAAGATACAATTGTGACCTACTTTGAGGGGATGAATAACGACTTATCACTTTAAGACACTTTGCAAACATG TTACTAAAAAAAGGTGCCTAGCCAAGGAAAAAACCATTCACTTGGAATTAAAATTGTGGATGTCACTTCAGAGATGACTTTAACATAAAT GCTGAAAGTTCATTCACCTCACAAATGTGGCAGTTTTCTCTGTGGAGAATGGTGGTCTCCGTGGCAGACTGGCTCTCCAAATTAAATGAA ACTCATTGACAGACCTGGGACCTTTTATGTGAGTGGACAGACAAGATCTTGGTTTGGCTTCATGTACTGTTTTCTAGAGAGAGTGCTACG AAAAACTTATGATGCTTTTATGTGATAACCAATATAATGCTTTAATATGTTAATTCTTTGTGATGCTATATACATAGTTTTTATAGTTTT ATGAAACCACTTTGTTAAACTTATCTGGATTTTAAGACACTTGTAAACAAATGGTTTGTTAGTAAAATTGGGGCATTAAGAGTTTTACAG >3916_3916_8_ALDH5A1-DCDC2_ALDH5A1_chr6_24495578_ENST00000546278_DCDC2_chr6_24178860_ENST00000378454_length(amino acids)=185AA_BP=50 MQPSASSHAFPARPRGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGREA TDAPEQVEEILDHSEQQARPARVNGGTDEENGEELQQVNNELQLVLDKERKSQGAGSGQDEADVDPQRPPRPEVKITSPEENENNQQNKD -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ALDH5A1-DCDC2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ALDH5A1-DCDC2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ALDH5A1-DCDC2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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