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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:IKBKAP-PTPN3 (FusionGDB2 ID:39361)

Fusion Gene Summary for IKBKAP-PTPN3

Fusion gene summary

Fusion gene information	Fusion gene name: IKBKAP-PTPN3
	Fusion gene ID: 39361
		Hgene	Tgene
	Gene symbol	IKBKAP	PTPN3
	Gene ID	8518	5774
	Gene name	elongator complex protein 1	protein tyrosine phosphatase non-receptor type 3
	Synonyms	DYS\|FD\|IKAP\|IKBKAP\|IKI3\|TOT1	PTP-H1\|PTPH1
	Cytomap	9q31.3	9q31.3
	Type of gene	protein-coding	protein-coding
	Description	elongator complex protein 1IKK complex-associated proteinelongator acetyltransferase complex subunit 1ikappaB kinase complex-associated proteininhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein	tyrosine-protein phosphatase non-receptor type 3cytoskeletal-associated protein tyrosine phosphataseprotein-tyrosine phosphatase H1
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000374647, ENST00000537196, ENST00000467959,	ENST00000497739, ENST00000262539, ENST00000374541, ENST00000394827, ENST00000412145, ENST00000446349,
Fusion gene scores	* DoF score	8 X 7 X 5=280	7 X 7 X 7=343
	# samples	9	10
	** MAII score	log2(9/280*10)=-1.63742992061529 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(10/343*10)=-1.77820857639809 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: IKBKAP [Title/Abstract] AND PTPN3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	IKBKAP(111673289)-PTPN3(112153841), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	PTPN3	GO:0006470	protein dephosphorylation	10364224
Tgene	PTPN3	GO:0045930	negative regulation of mitotic cell cycle	10364224
Tgene	PTPN3	GO:0098902	regulation of membrane depolarization during action potential	16930557
Tgene	PTPN3	GO:2000649	regulation of sodium ion transmembrane transporter activity	16930557

Fusion gene breakpoints across IKBKAP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PTPN3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	ESCA	TCGA-L5-A8NI	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-

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Fusion Gene ORF analysis for IKBKAP-PTPN3

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000374647	ENST00000497739	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
5CDS-5UTR	ENST00000537196	ENST00000497739	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
In-frame	ENST00000374647	ENST00000262539	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
In-frame	ENST00000374647	ENST00000374541	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
In-frame	ENST00000374647	ENST00000394827	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
In-frame	ENST00000374647	ENST00000412145	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
In-frame	ENST00000374647	ENST00000446349	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
In-frame	ENST00000537196	ENST00000262539	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
In-frame	ENST00000537196	ENST00000374541	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
In-frame	ENST00000537196	ENST00000394827	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
In-frame	ENST00000537196	ENST00000412145	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
In-frame	ENST00000537196	ENST00000446349	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
intron-3CDS	ENST00000467959	ENST00000262539	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
intron-3CDS	ENST00000467959	ENST00000374541	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
intron-3CDS	ENST00000467959	ENST00000394827	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
intron-3CDS	ENST00000467959	ENST00000412145	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
intron-3CDS	ENST00000467959	ENST00000446349	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-
intron-5UTR	ENST00000467959	ENST00000497739	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000374647	IKBKAP	chr9	111673289	-	ENST00000412145	PTPN3	chr9	112153841	-	6319	1668	278	1744	488
ENST00000374647	IKBKAP	chr9	111673289	-	ENST00000446349	PTPN3	chr9	112153841	-	6319	1668	278	1744	488
ENST00000374647	IKBKAP	chr9	111673289	-	ENST00000374541	PTPN3	chr9	112153841	-	6313	1668	278	1744	488
ENST00000374647	IKBKAP	chr9	111673289	-	ENST00000262539	PTPN3	chr9	112153841	-	2641	1668	278	1744	488
ENST00000374647	IKBKAP	chr9	111673289	-	ENST00000394827	PTPN3	chr9	112153841	-	2926	1668	278	1744	488
ENST00000537196	IKBKAP	chr9	111673289	-	ENST00000412145	PTPN3	chr9	112153841	-	5361	710	677	1498	273
ENST00000537196	IKBKAP	chr9	111673289	-	ENST00000446349	PTPN3	chr9	112153841	-	5361	710	677	1498	273
ENST00000537196	IKBKAP	chr9	111673289	-	ENST00000374541	PTPN3	chr9	112153841	-	5355	710	677	1498	273
ENST00000537196	IKBKAP	chr9	111673289	-	ENST00000262539	PTPN3	chr9	112153841	-	1683	710	677	1498	273
ENST00000537196	IKBKAP	chr9	111673289	-	ENST00000394827	PTPN3	chr9	112153841	-	1968	710	677	1498	273

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000374647	ENST00000412145	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-	0.001165563	0.99883443
ENST00000374647	ENST00000446349	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-	0.001165563	0.99883443
ENST00000374647	ENST00000374541	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-	0.001161671	0.99883837
ENST00000374647	ENST00000262539	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-	0.004170456	0.9958295
ENST00000374647	ENST00000394827	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-	0.003329303	0.99667066
ENST00000537196	ENST00000412145	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-	0.000835071	0.99916494
ENST00000537196	ENST00000446349	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-	0.000835071	0.99916494
ENST00000537196	ENST00000374541	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-	0.000836733	0.99916327
ENST00000537196	ENST00000262539	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-	0.000994495	0.9990055
ENST00000537196	ENST00000394827	IKBKAP	chr9	111673289	-	PTPN3	chr9	112153841	-	0.001149392	0.9988506

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Fusion Genomic Features for IKBKAP-PTPN3

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for IKBKAP-PTPN3

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:111673289/chr9:112153841)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

PTPN3

chr9:111673289

chr9:112153841

ENST00000412145

646_901

520

783.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN3

chr9:111673289

chr9:112153841

ENST00000446349

510_582

475

738.0

Domain

PDZ

Tgene

PTPN3

chr9:111673289

chr9:112153841

ENST00000446349

646_901

475

738.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN3

chr9:111673289

chr9:112153841

ENST00000374541

842_848

651

914.0

Region

Substrate binding

Tgene

PTPN3

chr9:111673289

chr9:112153841

ENST00000412145

842_848

520

783.0

Region

Substrate binding

Tgene

PTPN3

chr9:111673289

chr9:112153841

ENST00000446349

842_848

475

738.0

Region

Substrate binding

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

PTPN3

chr9:111673289

chr9:112153841

ENST00000374541

29_312

651

914.0

Domain

FERM

Tgene

PTPN3

chr9:111673289

chr9:112153841

ENST00000374541

510_582

651

914.0

Domain

PDZ

Tgene

PTPN3

chr9:111673289

chr9:112153841

ENST00000374541

646_901

651

914.0

Domain

Tyrosine-protein phosphatase

Tgene

PTPN3

chr9:111673289

chr9:112153841

ENST00000412145

29_312

520

783.0

Domain

FERM

Tgene

PTPN3

chr9:111673289

chr9:112153841

ENST00000412145

510_582

520

783.0

Domain

PDZ

Tgene

PTPN3

chr9:111673289

chr9:112153841

ENST00000446349

29_312

475

738.0

Domain

FERM

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Fusion Gene Sequence for IKBKAP-PTPN3

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>39361_39361_1_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000374647_PTPN3_chr9_112153841_ENST00000262539_length(transcript)=2641nt_BP=1668nt
AGTGCTGCGGCTGCCTAGTTGACGCACCCATTGAGTCGCTGGCTTCTTTGCAGCGCTTCAGCGTTTTCCCCTGGAGGGCGCCTCCATCCT
TGGAGGCCTAGTGCCGTCGGAGAGAGAGCGGGAGCCGCGGACAGAGACGCGTGCGCAATTCGGAGCCGACTCTGGGTGCGGACTGTGGGA
GCTGACTCTGGGTAGCCGGCTGCGCGTGGCTGGGGAGGCGAGGCCGGACGCACCTCTGTTTGGGGGTCCTCAGAGATTAATGATTCATCA
AGGGATAGTTGTACTTGTCTCGTGGGAATCACTTCATCATGCGAAATCTGAAATTATTTCGGACCCTGGAGTTCAGGGATATTCAAGGTC
CAGGGAATCCTCAGTGCTTCTCTCTCCGAACTGAACAGGGGACGGTGCTCATTGGTTCAGAACATGGCCTGATAGAAGTAGACCCTGTCT
CAAGAGAAGTGAAAAATGAAGTTTCTTTGGTGGCAGAAGGCTTTCTCCCAGAGGATGGAAGTGGCCGCATTGTTGGTGTTCAGGACTTGC
TGGATCAGGAGTCTGTGTGTGTGGCCACAGCCTCTGGAGACGTCATACTCTGCAGTCTCAGCACACAACAGCTGGAGTGTGTTGGGAGTG
TAGCCAGTGGTATCTCTGTTATGAGTTGGAGTCCTGACCAAGAGCTGGTGCTTCTTGCCACAGGTCAACAGACCCTGATTATGATGACAA
AAGATTTTGAGCCAATCCTGGAGCAGCAGATCCATCAGGATGATTTTGGTGAAAGCAAGTTTATCACTGTTGGATGGGGTAGGAAGGAGA
CACAGTTCCATGGATCAGAAGGCAGACAAGCAGCTTTTCAGATGCAAATGCATGAGTCTGCTTTGCCCTGGGATGACCATAGACCACAAG
TTACCTGGCGGGGGGATGGACAGTTTTTTGCTGTGAGTGTTGTTTGCCCAGAAACAGGGGCTCGGAAGGTCAGAGTGTGGAACCGAGAGT
TTGCTTTGCAGTCAACCAGTGAGCCTGTGGCAGGACTGGGACCAGCCCTGGCTTGGAAACCCTCAGGCAGTTTGATTGCATCTACACAAG
ATAAACCCAACCAGCAGGATATTGTGTTTTTTGAGAAAAATGGACTCCTTCATGGACACTTTACACTTCCCTTCCTTAAAGATGAGGTTA
AGGTAAATGACTTGCTCTGGAATGCAGATTCCTCTGTGCTTGCAGTCTGGCTGGAAGACCTTCAGAGAGAAGAAAGCTCCATTCCGAAAA
CCTGTGTTCAGCTCTGGACTGTTGGAAACTATCACTGGTATCTCAAGCAAAGTTTATCCTTCAGCACCTGTGGGAAGAGCAAGATTGTGT
CTCTGATGTGGGACCCTGTGACCCCATACCGGCTGCATGTTCTCTGTCAGGGCTGGCATTACCTCGCCTATGATTGGCACTGGACGACTG
ACCGGAGCGTGGGAGATAATTCAAGTGACTTGTCCAATGTGGCTGTCATTGATGGAAACAGGGTGTTGGTGACAGTCTTCCGGCAGACTG
TGGTTCCGCCTCCCATGTGCACCTACCAACTGCTGTTCCCACACCCTGTGAATCAAGTCACATTCTTAGCACACCCTCAAAAGAGTAATG
ACCTTGCTGTTCTAGATGCCAGTAACCAGATTTCTGTTTATAAATGTGCAACTCTACAGAAAAAAGCCAGGTTTGGCCATCACGTTTGCA
AAGCTGCCTCAAAATTTGGACAAAAACCGATATAAAGATGTGCTGCCTTATGACACCACCCGGGTATTATTGCAGGGAAATGAAGATTAT
ATTAATGCAAGTTACGTGAACATGGAAATTCCTGCTGCTAACCTTGTGAACAAGTACATCGCCACTCAGGGGCCCCTGCCGCATACCTGT
GCACAGTTTTGGCAGGTTGTCTGGGATCAGAAGTTGTCACTCATTGTCATGTTGACGACTCTCACAGAACGAGGGCGGACCAAATGTCAC
CAGTACTGGCCAGATCCCCCCGACGTCATGAACCACGGCGGCTTTCACATCCAGTGTCAGTCAGAGGACTGCACCATCGCCTATGTGTCC
CGAGAAATGCTGGTCACAAACACCCAGACCGGGGAAGAACACACAGTGACACATCTCCAGTACGTCGCATGGCCTGACCACGGTGTGCCC
GATGACTCCTCCGACTTTCTGGAATTTGTAAACTATGTGAGGTCTCTGAGAGTGGACAGCGAGCCCGTCCTAGTTCACTGCAGTGCTGGA
ATAGGTCGAACCGGTGTGTTGGTCACTATGGAAACAGCCATGTGCCTAACTGAGAGGAACCTGCCCATTTACCCACTGGATATTGTCCGA
AAAATGCGAGACCAGCGCGCCATGATGGTGCAGACATCAAGCCAGTACAAGTTTGTGTGTGAAGCGATTCTTCGTGTGTATGAAGAAGGT
TTAGTCCAAATGCTGGATCCTAGTTAAGACAACTGTGAAAAAGTTCATTCCTCTTTCCCAAGGGCATCCTCCTTGAAAGAGGAGGACAGA
CCTCTCTGGAAGCAGCAAGAGGAACCAGTAGCTGTGGGAAAGGAATGGGCACCTCTGAACCCAGGCACTTTAAACTTCTATAGAAAAGAT

>39361_39361_1_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000374647_PTPN3_chr9_112153841_ENST00000262539_length(amino acids)=488AA_BP=463
MYLSRGNHFIMRNLKLFRTLEFRDIQGPGNPQCFSLRTEQGTVLIGSEHGLIEVDPVSREVKNEVSLVAEGFLPEDGSGRIVGVQDLLDQ
ESVCVATASGDVILCSLSTQQLECVGSVASGISVMSWSPDQELVLLATGQQTLIMMTKDFEPILEQQIHQDDFGESKFITVGWGRKETQF
HGSEGRQAAFQMQMHESALPWDDHRPQVTWRGDGQFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGLGPALAWKPSGSLIASTQDKP
NQQDIVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSVLAVWLEDLQREESSIPKTCVQLWTVGNYHWYLKQSLSFSTCGKSKIVSLM
WDPVTPYRLHVLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDLA

--------------------------------------------------------------
>39361_39361_2_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000374647_PTPN3_chr9_112153841_ENST00000374541_length(transcript)=6313nt_BP=1668nt
AGTGCTGCGGCTGCCTAGTTGACGCACCCATTGAGTCGCTGGCTTCTTTGCAGCGCTTCAGCGTTTTCCCCTGGAGGGCGCCTCCATCCT
TGGAGGCCTAGTGCCGTCGGAGAGAGAGCGGGAGCCGCGGACAGAGACGCGTGCGCAATTCGGAGCCGACTCTGGGTGCGGACTGTGGGA
GCTGACTCTGGGTAGCCGGCTGCGCGTGGCTGGGGAGGCGAGGCCGGACGCACCTCTGTTTGGGGGTCCTCAGAGATTAATGATTCATCA
AGGGATAGTTGTACTTGTCTCGTGGGAATCACTTCATCATGCGAAATCTGAAATTATTTCGGACCCTGGAGTTCAGGGATATTCAAGGTC
CAGGGAATCCTCAGTGCTTCTCTCTCCGAACTGAACAGGGGACGGTGCTCATTGGTTCAGAACATGGCCTGATAGAAGTAGACCCTGTCT
CAAGAGAAGTGAAAAATGAAGTTTCTTTGGTGGCAGAAGGCTTTCTCCCAGAGGATGGAAGTGGCCGCATTGTTGGTGTTCAGGACTTGC
TGGATCAGGAGTCTGTGTGTGTGGCCACAGCCTCTGGAGACGTCATACTCTGCAGTCTCAGCACACAACAGCTGGAGTGTGTTGGGAGTG
TAGCCAGTGGTATCTCTGTTATGAGTTGGAGTCCTGACCAAGAGCTGGTGCTTCTTGCCACAGGTCAACAGACCCTGATTATGATGACAA
AAGATTTTGAGCCAATCCTGGAGCAGCAGATCCATCAGGATGATTTTGGTGAAAGCAAGTTTATCACTGTTGGATGGGGTAGGAAGGAGA
CACAGTTCCATGGATCAGAAGGCAGACAAGCAGCTTTTCAGATGCAAATGCATGAGTCTGCTTTGCCCTGGGATGACCATAGACCACAAG
TTACCTGGCGGGGGGATGGACAGTTTTTTGCTGTGAGTGTTGTTTGCCCAGAAACAGGGGCTCGGAAGGTCAGAGTGTGGAACCGAGAGT
TTGCTTTGCAGTCAACCAGTGAGCCTGTGGCAGGACTGGGACCAGCCCTGGCTTGGAAACCCTCAGGCAGTTTGATTGCATCTACACAAG
ATAAACCCAACCAGCAGGATATTGTGTTTTTTGAGAAAAATGGACTCCTTCATGGACACTTTACACTTCCCTTCCTTAAAGATGAGGTTA
AGGTAAATGACTTGCTCTGGAATGCAGATTCCTCTGTGCTTGCAGTCTGGCTGGAAGACCTTCAGAGAGAAGAAAGCTCCATTCCGAAAA
CCTGTGTTCAGCTCTGGACTGTTGGAAACTATCACTGGTATCTCAAGCAAAGTTTATCCTTCAGCACCTGTGGGAAGAGCAAGATTGTGT
CTCTGATGTGGGACCCTGTGACCCCATACCGGCTGCATGTTCTCTGTCAGGGCTGGCATTACCTCGCCTATGATTGGCACTGGACGACTG
ACCGGAGCGTGGGAGATAATTCAAGTGACTTGTCCAATGTGGCTGTCATTGATGGAAACAGGGTGTTGGTGACAGTCTTCCGGCAGACTG
TGGTTCCGCCTCCCATGTGCACCTACCAACTGCTGTTCCCACACCCTGTGAATCAAGTCACATTCTTAGCACACCCTCAAAAGAGTAATG
ACCTTGCTGTTCTAGATGCCAGTAACCAGATTTCTGTTTATAAATGTGCAACTCTACAGAAAAAAGCCAGGTTTGGCCATCACGTTTGCA
AAGCTGCCTCAAAATTTGGACAAAAACCGATATAAAGATGTGCTGCCTTATGACACCACCCGGGTATTATTGCAGGGAAATGAAGATTAT
ATTAATGCAAGTTACGTGAACATGGAAATTCCTGCTGCTAACCTTGTGAACAAGTACATCGCCACTCAGGGGCCCCTGCCGCATACCTGT
GCACAGTTTTGGCAGGTTGTCTGGGATCAGAAGTTGTCACTCATTGTCATGTTGACGACTCTCACAGAACGAGGGCGGACCAAATGTCAC
CAGTACTGGCCAGATCCCCCCGACGTCATGAACCACGGCGGCTTTCACATCCAGTGTCAGTCAGAGGACTGCACCATCGCCTATGTGTCC
CGAGAAATGCTGGTCACAAACACCCAGACCGGGGAAGAACACACAGTGACACATCTCCAGTACGTCGCATGGCCTGACCACGGTGTGCCC
GATGACTCCTCCGACTTTCTGGAATTTGTAAACTATGTGAGGTCTCTGAGAGTGGACAGCGAGCCCGTCCTAGTTCACTGCAGTGCTGGA
ATAGGTCGAACCGGTGTGTTGGTCACTATGGAAACAGCCATGTGCCTAACTGAGAGGAACCTGCCCATTTACCCACTGGATATTGTCCGA
AAAATGCGAGACCAGCGCGCCATGATGGTGCAGACATCAAGCCAGTACAAGTTTGTGTGTGAAGCGATTCTTCGTGTGTATGAAGAAGGT
TTAGTCCAAATGCTGGATCCTAGTTAAGACAACTGTGAAAAAGTTCATTCCTCTTTCCCAAGGGCATCCTCCTTGAAAGAGGAGGACAGA
CCTCTCTGGAAGCAGCAAGAGGAACCAGTAGCTGTGGGAAAGGAATGGGCACCTCTGAACCCAGGCACTTTAAACTTCTATAGAAAAGAT
ATCGTGTACATAGGAACTGGTGTAGATAAGCATGCAATTATGGCATCATTTAGGCCTGTATTTCTATGGAAAGATACAAAAAGGATCTCA
GTTTGGGGCCTGTCCTAATGCCTTCTTCCCTAACATCACCACACACACCCCTGTCGGCATCCTGGAGCAATTGAGACCGGACACCCACAG
AGCTGTTGTCCTCCCAGCAACAAGATGGTGTGGTTATCTTGGGTCATTTGGATGTTTTGTTTGTTTCTGTGTGTCAGACTGTAAGGGCTG
AGCTTTCTGTGCTTCTAGGTGGAGCTGGAACAATTCAGATTCACCCGCCCTGATGCTAAGGAAACCCTGACGTATGTACTAGATGGCAGG
GCACTGGGGGTCAGGCTGAAGGCTGAGCAACACCTCTCTGCCCTCCCTCCCTTTGTCCCATCTCCCAGCGACTTCCAATATTCATGTTTC
TGAGAATTGTGTCCCTCTTCAGGTTCCCTCTTGGTGCCTAACCTGGATTAGTAATGTGCATTCAGGTGAATTTTCAGCTGAGGCTCTGAG
AACTGGTACTCTCAGTGTGTTCTGGTCATCTTGTGGCTTAGTTGTAGAAGCAGGTGTGTCTCTTGCCTCTGCTTGCCTCCTACTGCACAC
TCAGCACCCAGGACTGGAATCACCGACTACTGAATCTCCTACATGTATTGCTGCTACTTCAAGCTCCTCCACTTGAAACCTTATGATTTT
CCCAAGGGGAGATGGGACAGTGTCATCTAAATATTCCGAATGTTTGGCCTTCTGAGAAAAGAGCTTCTAGTAATTGAACCATGGGAAACC
CAGCTTCTGGAGGGTTGGCCGTGGGGCTGTGTACATGTGTGTGCCCAGGGGTGAGTGTTTCTCAGGATTCCTAACGATTCAAATTACCGT
TGAGTATATATAAAGAATGAGTCTCTGTATGGAAGAACAAATGTGTGCATTCACCCCCAGTCACAATGGTCTCCATTGCATTTCAAAGGA
GAGGATCAGACTATCTGAATATAAACACAATCTGATGTTAATTTATTCTAAGAACACCATCATTTTGATTGTCCTAAAGAATTCTGCCTT
TGTGAATACCGTGTTAAATTTTTTTAAATTTGTGACAGGATTGTAGCAAATTATTATTTAAGGAAAATAAATTGTGTAAACATTTAATGT
GGTATTTTTGAACAGCGGTTTTTATGTACTCAGAAGAGGAAGTAAAGCCAGGTTCTTAATGGTATTTATAGAAAAGATGTTTTCATATTA
TAATGCACATAAATGAAGCCATTTTGATATTCAGCAAATTCGGTGCCAATTGAATAGTTTGCTGGTAGCAAGACGGATGAAGACCTATAT
GGGAGATTCTTTATCTCTAGAGCTAGCATATTTACTTGCATACTTTGTTTCTTTTCCACATGGATATTTTACTGCTAAATGGCAGAGGTG
GGAGGGAGATGTCACACAGTACCATAACCCCATATTGAAAACAAGAAACCACCAGAAAGTTTGCAGCTAAGGGGCAGGGGATTCAGTTCC
TACGCCCACTCAGCACTAACTACTTGCGGGCCTGGTTGCTTAGAAGCTCTACCTCTCTTTCATTATCTGTAAAATAGAAACAATACTTAG
GACTTTAGTTGGAACATGAGGATTGAATAAGATCACGCTATTCATGTGACTTTTTATCGGCTAGAACAGCAACAGACACTGCTGTGGGTG
AGTTACTTAGAAAAGTTTAGTTATCAGTGATTAGCCCAAAAACACATCAGTCAAAAATAGAATCCACTGGATTTTTGTCTCTCTTTTTAG
AGACAGGGTCTCACTGTCGCCCAGGCTGGAGTACAGTGGCATGATCATTGTTCACTGCAGCCTCAAATTCCTGGGCTCAAGCAATCCTCG
CACCTCAGCCTCCTGAGTAGCCGGGACTATAGGCACATGCCACCTCACCTGGCTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTAGAGACAGGATCTTGATGTGTTGCCTAGGCTGGTCTCAAACTCCTGGCCTCAAGTGATCTTCC
CACCTCAGCCTCCAAAACTGTTGGGATTATAGGCGTGAGCCACTGTGCCCAGCCTAACTGGGTTTTTATGAGAGGAAAATAGAAAATGCT
CTTCTAGAAGAGAGAGAACAAGAGCACAAAATAATCTGGACTCACAAAAATTCAGCAAGCTCCAAGAAAGGGGGATGGAGGGAACGCTGG
CAAAAATTTAAATGCCATTAGGATATTTAGCAAGTTATTACTGTTTGGTAAAAATGCATCATCACCCTGTGTGCAAAATGCTTGCAAAGT
AGTCTAAATGTCTTTGGAGATGGGTGTTTTACTGCTTTTTTCCAAAAACAAATTGTTTATTATGGTTGCAGAAATGCAGCCATTACGGTC
ACATAAATTTCTAAAAAGCCTACCAAAGGTTGCAAGCAGTCTTCTGCCACTGGGCAGGCCAGCAGTTCAGACCCAGCGAGGTTGCCAGGA
ACAAATCCAGGAAATACTGGGAAGAACAAGACAAGAGAATTACCTAAAAGAGCAAACAATTCAAGTAAATCCTGTAGCTATTACCACTTA
AAATCCGTAGCTCAAGATTCCTGTTTCACCACCTTATACACTTAAGCAATTATACTTAAGCCTTTTTTTAGTCCTAAGTGAAGAACTACA
TCAGAATCAGGATAAGTATTTTGCCTGGGAAATTTGGCTGCATATGAATGGAGAAGACATTTACATCCTATGTTCTGGCACTTTCTGAAA
GATCTAATTAAACATGTTGATGTGCCAATTTAATCAAGATGAGAGATCCCTGCTGGTGTCACCCTCTAGAACCTGCACTTGGTGTTTTGA
CTTTCCAGAAGAAAAAAATGCAACTTTGGTTAGGGGGCAGTGGTTGGATCACACAGTTGTCTTTCGTTTCCTACCACAGTAATTCATATT
TAAATATGCTTTTAGATTAGTGTGGATACTATTGCTGCTGTGTTGCTACCTGACCTTTTTCTGGGGGGGGTACCTCAGAAATGAGCATTT
GAGGGCAAGCGAAAAAGCCCTCTTCATCCTCCAGAGGCAACAAAGAGGCAGCAGAAATGGGGAAAGATTGTGAGAGGCAGGGCTTGGGTC
TAGACCTGGACTTAGGCAAGATATGTTGCCCTCAACCCTGAGTTTTCTTATATGTAAAAAGGGAAGGTTGGGCTGGACTAGATGAGGTCA
AGATTTGCCATTCTGGGAGGCTGATATTCCAGAGAATCAAAATTAATCCTAAACCAAAGCTTTATGGCTGCTACAGAGACATGTCACATT
TCTGAGACTTGTCACCAAGAGTTTGTCCCTCAGACTTTGGCGCTGTTGAATGCAAAGACAAGGATGGCCACCTTCTGGTTCTTGCCTGTT
GTCCTCAGCTGAGAGCAGTCTCGGTAAAGGTGGCAAAGATTCTGTGACCTCAGACCGGGGACCAAATGCTTGGGAGTCTGATGGCCGGGC
TGGGCCACCATTCTCATAGCTCTCATTCTGTTTGGAGCAACCAAAGGATTTGTGTGAAGTTATTTGGAAAAGGACCTTAACTGAGCAGTA
ATCTTTTTTCTGTATATTTGGAATGTTTTTCATTCTGACCTGTTCTGTCAGTGATTCTACTGAAAAACAATTTAATCAATATAAAAATGT

>39361_39361_2_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000374647_PTPN3_chr9_112153841_ENST00000374541_length(amino acids)=488AA_BP=463
MYLSRGNHFIMRNLKLFRTLEFRDIQGPGNPQCFSLRTEQGTVLIGSEHGLIEVDPVSREVKNEVSLVAEGFLPEDGSGRIVGVQDLLDQ
ESVCVATASGDVILCSLSTQQLECVGSVASGISVMSWSPDQELVLLATGQQTLIMMTKDFEPILEQQIHQDDFGESKFITVGWGRKETQF
HGSEGRQAAFQMQMHESALPWDDHRPQVTWRGDGQFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGLGPALAWKPSGSLIASTQDKP
NQQDIVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSVLAVWLEDLQREESSIPKTCVQLWTVGNYHWYLKQSLSFSTCGKSKIVSLM
WDPVTPYRLHVLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDLA

--------------------------------------------------------------
>39361_39361_3_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000374647_PTPN3_chr9_112153841_ENST00000394827_length(transcript)=2926nt_BP=1668nt
AGTGCTGCGGCTGCCTAGTTGACGCACCCATTGAGTCGCTGGCTTCTTTGCAGCGCTTCAGCGTTTTCCCCTGGAGGGCGCCTCCATCCT
TGGAGGCCTAGTGCCGTCGGAGAGAGAGCGGGAGCCGCGGACAGAGACGCGTGCGCAATTCGGAGCCGACTCTGGGTGCGGACTGTGGGA
GCTGACTCTGGGTAGCCGGCTGCGCGTGGCTGGGGAGGCGAGGCCGGACGCACCTCTGTTTGGGGGTCCTCAGAGATTAATGATTCATCA
AGGGATAGTTGTACTTGTCTCGTGGGAATCACTTCATCATGCGAAATCTGAAATTATTTCGGACCCTGGAGTTCAGGGATATTCAAGGTC
CAGGGAATCCTCAGTGCTTCTCTCTCCGAACTGAACAGGGGACGGTGCTCATTGGTTCAGAACATGGCCTGATAGAAGTAGACCCTGTCT
CAAGAGAAGTGAAAAATGAAGTTTCTTTGGTGGCAGAAGGCTTTCTCCCAGAGGATGGAAGTGGCCGCATTGTTGGTGTTCAGGACTTGC
TGGATCAGGAGTCTGTGTGTGTGGCCACAGCCTCTGGAGACGTCATACTCTGCAGTCTCAGCACACAACAGCTGGAGTGTGTTGGGAGTG
TAGCCAGTGGTATCTCTGTTATGAGTTGGAGTCCTGACCAAGAGCTGGTGCTTCTTGCCACAGGTCAACAGACCCTGATTATGATGACAA
AAGATTTTGAGCCAATCCTGGAGCAGCAGATCCATCAGGATGATTTTGGTGAAAGCAAGTTTATCACTGTTGGATGGGGTAGGAAGGAGA
CACAGTTCCATGGATCAGAAGGCAGACAAGCAGCTTTTCAGATGCAAATGCATGAGTCTGCTTTGCCCTGGGATGACCATAGACCACAAG
TTACCTGGCGGGGGGATGGACAGTTTTTTGCTGTGAGTGTTGTTTGCCCAGAAACAGGGGCTCGGAAGGTCAGAGTGTGGAACCGAGAGT
TTGCTTTGCAGTCAACCAGTGAGCCTGTGGCAGGACTGGGACCAGCCCTGGCTTGGAAACCCTCAGGCAGTTTGATTGCATCTACACAAG
ATAAACCCAACCAGCAGGATATTGTGTTTTTTGAGAAAAATGGACTCCTTCATGGACACTTTACACTTCCCTTCCTTAAAGATGAGGTTA
AGGTAAATGACTTGCTCTGGAATGCAGATTCCTCTGTGCTTGCAGTCTGGCTGGAAGACCTTCAGAGAGAAGAAAGCTCCATTCCGAAAA
CCTGTGTTCAGCTCTGGACTGTTGGAAACTATCACTGGTATCTCAAGCAAAGTTTATCCTTCAGCACCTGTGGGAAGAGCAAGATTGTGT
CTCTGATGTGGGACCCTGTGACCCCATACCGGCTGCATGTTCTCTGTCAGGGCTGGCATTACCTCGCCTATGATTGGCACTGGACGACTG
ACCGGAGCGTGGGAGATAATTCAAGTGACTTGTCCAATGTGGCTGTCATTGATGGAAACAGGGTGTTGGTGACAGTCTTCCGGCAGACTG
TGGTTCCGCCTCCCATGTGCACCTACCAACTGCTGTTCCCACACCCTGTGAATCAAGTCACATTCTTAGCACACCCTCAAAAGAGTAATG
ACCTTGCTGTTCTAGATGCCAGTAACCAGATTTCTGTTTATAAATGTGCAACTCTACAGAAAAAAGCCAGGTTTGGCCATCACGTTTGCA
AAGCTGCCTCAAAATTTGGACAAAAACCGATATAAAGATGTGCTGCCTTATGACACCACCCGGGTATTATTGCAGGGAAATGAAGATTAT
ATTAATGCAAGTTACGTGAACATGGAAATTCCTGCTGCTAACCTTGTGAACAAGTACATCGCCACTCAGGGGCCCCTGCCGCATACCTGT
GCACAGTTTTGGCAGGTTGTCTGGGATCAGAAGTTGTCACTCATTGTCATGTTGACGACTCTCACAGAACGAGGGCGGACCAAATGTCAC
CAGTACTGGCCAGATCCCCCCGACGTCATGAACCACGGCGGCTTTCACATCCAGTGTCAGTCAGAGGACTGCACCATCGCCTATGTGTCC
CGAGAAATGCTGGTCACAAACACCCAGACCGGGGAAGAACACACAGTGACACATCTCCAGTACGTCGCATGGCCTGACCACGGTGTGCCC
GATGACTCCTCCGACTTTCTGGAATTTGTAAACTATGTGAGGTCTCTGAGAGTGGACAGCGAGCCCGTCCTAGTTCACTGCAGTGCTGGA
ATAGGTCGAACCGGTGTGTTGGTCACTATGGAAACAGCCATGTGCCTAACTGAGAGGAACCTGCCCATTTACCCACTGGATATTGTCCGA
AAAATGCGAGACCAGCGCGCCATGATGGTGCAGACATCAAGCCAGTACAAGTTTGTGTGTGAAGCGATTCTTCGTGTGTATGAAGAAGGT
TTAGTCCAAATGCTGGATCCTAGTTAAGACAACTGTGAAAAAGTTCATTCCTCTTTCCCAAGGGCATCCTCCTTGAAAGAGGAGGACAGA
CCTCTCTGGAAGCAGCAAGAGGAACCAGTAGCTGTGGGAAAGGAATGGGCACCTCTGAACCCAGGCACTTTAAACTTCTATAGAAAAGAT
ATCGTGTACATAGGAACTGGTGTAGATAAGCATGCAATTATGGCATCATTTAGGCCTGTATTTCTATGGAAAGATACAAAAAGGATCTCA
GTTTGGGGCCTGTCCTAATGCCTTCTTCCCTAACATCACCACACACACCCCTGTCGGCATCCTGGAGCAATTGAGACCGGACACCCACAG
AGCTGTTGTCCTCCCAGCAACAAGATGGTGTGGTTATCTTGGGTCATTTGGATGTTTTGTTTGTTTCTGTGTGTCAGACTGTAAGGGCTG

>39361_39361_3_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000374647_PTPN3_chr9_112153841_ENST00000394827_length(amino acids)=488AA_BP=463
MYLSRGNHFIMRNLKLFRTLEFRDIQGPGNPQCFSLRTEQGTVLIGSEHGLIEVDPVSREVKNEVSLVAEGFLPEDGSGRIVGVQDLLDQ
ESVCVATASGDVILCSLSTQQLECVGSVASGISVMSWSPDQELVLLATGQQTLIMMTKDFEPILEQQIHQDDFGESKFITVGWGRKETQF
HGSEGRQAAFQMQMHESALPWDDHRPQVTWRGDGQFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGLGPALAWKPSGSLIASTQDKP
NQQDIVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSVLAVWLEDLQREESSIPKTCVQLWTVGNYHWYLKQSLSFSTCGKSKIVSLM
WDPVTPYRLHVLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDLA

--------------------------------------------------------------
>39361_39361_4_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000374647_PTPN3_chr9_112153841_ENST00000412145_length(transcript)=6319nt_BP=1668nt
AGTGCTGCGGCTGCCTAGTTGACGCACCCATTGAGTCGCTGGCTTCTTTGCAGCGCTTCAGCGTTTTCCCCTGGAGGGCGCCTCCATCCT
TGGAGGCCTAGTGCCGTCGGAGAGAGAGCGGGAGCCGCGGACAGAGACGCGTGCGCAATTCGGAGCCGACTCTGGGTGCGGACTGTGGGA
GCTGACTCTGGGTAGCCGGCTGCGCGTGGCTGGGGAGGCGAGGCCGGACGCACCTCTGTTTGGGGGTCCTCAGAGATTAATGATTCATCA
AGGGATAGTTGTACTTGTCTCGTGGGAATCACTTCATCATGCGAAATCTGAAATTATTTCGGACCCTGGAGTTCAGGGATATTCAAGGTC
CAGGGAATCCTCAGTGCTTCTCTCTCCGAACTGAACAGGGGACGGTGCTCATTGGTTCAGAACATGGCCTGATAGAAGTAGACCCTGTCT
CAAGAGAAGTGAAAAATGAAGTTTCTTTGGTGGCAGAAGGCTTTCTCCCAGAGGATGGAAGTGGCCGCATTGTTGGTGTTCAGGACTTGC
TGGATCAGGAGTCTGTGTGTGTGGCCACAGCCTCTGGAGACGTCATACTCTGCAGTCTCAGCACACAACAGCTGGAGTGTGTTGGGAGTG
TAGCCAGTGGTATCTCTGTTATGAGTTGGAGTCCTGACCAAGAGCTGGTGCTTCTTGCCACAGGTCAACAGACCCTGATTATGATGACAA
AAGATTTTGAGCCAATCCTGGAGCAGCAGATCCATCAGGATGATTTTGGTGAAAGCAAGTTTATCACTGTTGGATGGGGTAGGAAGGAGA
CACAGTTCCATGGATCAGAAGGCAGACAAGCAGCTTTTCAGATGCAAATGCATGAGTCTGCTTTGCCCTGGGATGACCATAGACCACAAG
TTACCTGGCGGGGGGATGGACAGTTTTTTGCTGTGAGTGTTGTTTGCCCAGAAACAGGGGCTCGGAAGGTCAGAGTGTGGAACCGAGAGT
TTGCTTTGCAGTCAACCAGTGAGCCTGTGGCAGGACTGGGACCAGCCCTGGCTTGGAAACCCTCAGGCAGTTTGATTGCATCTACACAAG
ATAAACCCAACCAGCAGGATATTGTGTTTTTTGAGAAAAATGGACTCCTTCATGGACACTTTACACTTCCCTTCCTTAAAGATGAGGTTA
AGGTAAATGACTTGCTCTGGAATGCAGATTCCTCTGTGCTTGCAGTCTGGCTGGAAGACCTTCAGAGAGAAGAAAGCTCCATTCCGAAAA
CCTGTGTTCAGCTCTGGACTGTTGGAAACTATCACTGGTATCTCAAGCAAAGTTTATCCTTCAGCACCTGTGGGAAGAGCAAGATTGTGT
CTCTGATGTGGGACCCTGTGACCCCATACCGGCTGCATGTTCTCTGTCAGGGCTGGCATTACCTCGCCTATGATTGGCACTGGACGACTG
ACCGGAGCGTGGGAGATAATTCAAGTGACTTGTCCAATGTGGCTGTCATTGATGGAAACAGGGTGTTGGTGACAGTCTTCCGGCAGACTG
TGGTTCCGCCTCCCATGTGCACCTACCAACTGCTGTTCCCACACCCTGTGAATCAAGTCACATTCTTAGCACACCCTCAAAAGAGTAATG
ACCTTGCTGTTCTAGATGCCAGTAACCAGATTTCTGTTTATAAATGTGCAACTCTACAGAAAAAAGCCAGGTTTGGCCATCACGTTTGCA
AAGCTGCCTCAAAATTTGGACAAAAACCGATATAAAGATGTGCTGCCTTATGACACCACCCGGGTATTATTGCAGGGAAATGAAGATTAT
ATTAATGCAAGTTACGTGAACATGGAAATTCCTGCTGCTAACCTTGTGAACAAGTACATCGCCACTCAGGGGCCCCTGCCGCATACCTGT
GCACAGTTTTGGCAGGTTGTCTGGGATCAGAAGTTGTCACTCATTGTCATGTTGACGACTCTCACAGAACGAGGGCGGACCAAATGTCAC
CAGTACTGGCCAGATCCCCCCGACGTCATGAACCACGGCGGCTTTCACATCCAGTGTCAGTCAGAGGACTGCACCATCGCCTATGTGTCC
CGAGAAATGCTGGTCACAAACACCCAGACCGGGGAAGAACACACAGTGACACATCTCCAGTACGTCGCATGGCCTGACCACGGTGTGCCC
GATGACTCCTCCGACTTTCTGGAATTTGTAAACTATGTGAGGTCTCTGAGAGTGGACAGCGAGCCCGTCCTAGTTCACTGCAGTGCTGGA
ATAGGTCGAACCGGTGTGTTGGTCACTATGGAAACAGCCATGTGCCTAACTGAGAGGAACCTGCCCATTTACCCACTGGATATTGTCCGA
AAAATGCGAGACCAGCGCGCCATGATGGTGCAGACATCAAGCCAGTACAAGTTTGTGTGTGAAGCGATTCTTCGTGTGTATGAAGAAGGT
TTAGTCCAAATGCTGGATCCTAGTTAAGACAACTGTGAAAAAGTTCATTCCTCTTTCCCAAGGGCATCCTCCTTGAAAGAGGAGGACAGA
CCTCTCTGGAAGCAGCAAGAGGAACCAGTAGCTGTGGGAAAGGAATGGGCACCTCTGAACCCAGGCACTTTAAACTTCTATAGAAAAGAT
ATCGTGTACATAGGAACTGGTGTAGATAAGCATGCAATTATGGCATCATTTAGGCCTGTATTTCTATGGAAAGATACAAAAAGGATCTCA
GTTTGGGGCCTGTCCTAATGCCTTCTTCCCTAACATCACCACACACACCCCTGTCGGCATCCTGGAGCAATTGAGACCGGACACCCACAG
AGCTGTTGTCCTCCCAGCAACAAGATGGTGTGGTTATCTTGGGTCATTTGGATGTTTTGTTTGTTTCTGTGTGTCAGACTGTAAGGGCTG
AGCTTTCTGTGCTTCTAGGTGGAGCTGGAACAATTCAGATTCACCCGCCCTGATGCTAAGGAAACCCTGACGTATGTACTAGATGGCAGG
GCACTGGGGGTCAGGCTGAAGGCTGAGCAACACCTCTCTGCCCTCCCTCCCTTTGTCCCATCTCCCAGCGACTTCCAATATTCATGTTTC
TGAGAATTGTGTCCCTCTTCAGGTTCCCTCTTGGTGCCTAACCTGGATTAGTAATGTGCATTCAGGTGAATTTTCAGCTGAGGCTCTGAG
AACTGGTACTCTCAGTGTGTTCTGGTCATCTTGTGGCTTAGTTGTAGAAGCAGGTGTGTCTCTTGCCTCTGCTTGCCTCCTACTGCACAC
TCAGCACCCAGGACTGGAATCACCGACTACTGAATCTCCTACATGTATTGCTGCTACTTCAAGCTCCTCCACTTGAAACCTTATGATTTT
CCCAAGGGGAGATGGGACAGTGTCATCTAAATATTCCGAATGTTTGGCCTTCTGAGAAAAGAGCTTCTAGTAATTGAACCATGGGAAACC
CAGCTTCTGGAGGGTTGGCCGTGGGGCTGTGTACATGTGTGTGCCCAGGGGTGAGTGTTTCTCAGGATTCCTAACGATTCAAATTACCGT
TGAGTATATATAAAGAATGAGTCTCTGTATGGAAGAACAAATGTGTGCATTCACCCCCAGTCACAATGGTCTCCATTGCATTTCAAAGGA
GAGGATCAGACTATCTGAATATAAACACAATCTGATGTTAATTTATTCTAAGAACACCATCATTTTGATTGTCCTAAAGAATTCTGCCTT
TGTGAATACCGTGTTAAATTTTTTTAAATTTGTGACAGGATTGTAGCAAATTATTATTTAAGGAAAATAAATTGTGTAAACATTTAATGT
GGTATTTTTGAACAGCGGTTTTTATGTACTCAGAAGAGGAAGTAAAGCCAGGTTCTTAATGGTATTTATAGAAAAGATGTTTTCATATTA
TAATGCACATAAATGAAGCCATTTTGATATTCAGCAAATTCGGTGCCAATTGAATAGTTTGCTGGTAGCAAGACGGATGAAGACCTATAT
GGGAGATTCTTTATCTCTAGAGCTAGCATATTTACTTGCATACTTTGTTTCTTTTCCACATGGATATTTTACTGCTAAATGGCAGAGGTG
GGAGGGAGATGTCACACAGTACCATAACCCCATATTGAAAACAAGAAACCACCAGAAAGTTTGCAGCTAAGGGGCAGGGGATTCAGTTCC
TACGCCCACTCAGCACTAACTACTTGCGGGCCTGGTTGCTTAGAAGCTCTACCTCTCTTTCATTATCTGTAAAATAGAAACAATACTTAG
GACTTTAGTTGGAACATGAGGATTGAATAAGATCACGCTATTCATGTGACTTTTTATCGGCTAGAACAGCAACAGACACTGCTGTGGGTG
AGTTACTTAGAAAAGTTTAGTTATCAGTGATTAGCCCAAAAACACATCAGTCAAAAATAGAATCCACTGGATTTTTGTCTCTCTTTTTAG
AGACAGGGTCTCACTGTCGCCCAGGCTGGAGTACAGTGGCATGATCATTGTTCACTGCAGCCTCAAATTCCTGGGCTCAAGCAATCCTCG
CACCTCAGCCTCCTGAGTAGCCGGGACTATAGGCACATGCCACCTCACCTGGCTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTAGAGACAGGATCTTGATGTGTTGCCTAGGCTGGTCTCAAACTCCTGGCCTCAAGTGATCTTCC
CACCTCAGCCTCCAAAACTGTTGGGATTATAGGCGTGAGCCACTGTGCCCAGCCTAACTGGGTTTTTATGAGAGGAAAATAGAAAATGCT
CTTCTAGAAGAGAGAGAACAAGAGCACAAAATAATCTGGACTCACAAAAATTCAGCAAGCTCCAAGAAAGGGGGATGGAGGGAACGCTGG
CAAAAATTTAAATGCCATTAGGATATTTAGCAAGTTATTACTGTTTGGTAAAAATGCATCATCACCCTGTGTGCAAAATGCTTGCAAAGT
AGTCTAAATGTCTTTGGAGATGGGTGTTTTACTGCTTTTTTCCAAAAACAAATTGTTTATTATGGTTGCAGAAATGCAGCCATTACGGTC
ACATAAATTTCTAAAAAGCCTACCAAAGGTTGCAAGCAGTCTTCTGCCACTGGGCAGGCCAGCAGTTCAGACCCAGCGAGGTTGCCAGGA
ACAAATCCAGGAAATACTGGGAAGAACAAGACAAGAGAATTACCTAAAAGAGCAAACAATTCAAGTAAATCCTGTAGCTATTACCACTTA
AAATCCGTAGCTCAAGATTCCTGTTTCACCACCTTATACACTTAAGCAATTATACTTAAGCCTTTTTTTAGTCCTAAGTGAAGAACTACA
TCAGAATCAGGATAAGTATTTTGCCTGGGAAATTTGGCTGCATATGAATGGAGAAGACATTTACATCCTATGTTCTGGCACTTTCTGAAA
GATCTAATTAAACATGTTGATGTGCCAATTTAATCAAGATGAGAGATCCCTGCTGGTGTCACCCTCTAGAACCTGCACTTGGTGTTTTGA
CTTTCCAGAAGAAAAAAATGCAACTTTGGTTAGGGGGCAGTGGTTGGATCACACAGTTGTCTTTCGTTTCCTACCACAGTAATTCATATT
TAAATATGCTTTTAGATTAGTGTGGATACTATTGCTGCTGTGTTGCTACCTGACCTTTTTCTGGGGGGGGTACCTCAGAAATGAGCATTT
GAGGGCAAGCGAAAAAGCCCTCTTCATCCTCCAGAGGCAACAAAGAGGCAGCAGAAATGGGGAAAGATTGTGAGAGGCAGGGCTTGGGTC
TAGACCTGGACTTAGGCAAGATATGTTGCCCTCAACCCTGAGTTTTCTTATATGTAAAAAGGGAAGGTTGGGCTGGACTAGATGAGGTCA
AGATTTGCCATTCTGGGAGGCTGATATTCCAGAGAATCAAAATTAATCCTAAACCAAAGCTTTATGGCTGCTACAGAGACATGTCACATT
TCTGAGACTTGTCACCAAGAGTTTGTCCCTCAGACTTTGGCGCTGTTGAATGCAAAGACAAGGATGGCCACCTTCTGGTTCTTGCCTGTT
GTCCTCAGCTGAGAGCAGTCTCGGTAAAGGTGGCAAAGATTCTGTGACCTCAGACCGGGGACCAAATGCTTGGGAGTCTGATGGCCGGGC
TGGGCCACCATTCTCATAGCTCTCATTCTGTTTGGAGCAACCAAAGGATTTGTGTGAAGTTATTTGGAAAAGGACCTTAACTGAGCAGTA
ATCTTTTTTCTGTATATTTGGAATGTTTTTCATTCTGACCTGTTCTGTCAGTGATTCTACTGAAAAACAATTTAATCAATATAAAAATGT

>39361_39361_4_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000374647_PTPN3_chr9_112153841_ENST00000412145_length(amino acids)=488AA_BP=463
MYLSRGNHFIMRNLKLFRTLEFRDIQGPGNPQCFSLRTEQGTVLIGSEHGLIEVDPVSREVKNEVSLVAEGFLPEDGSGRIVGVQDLLDQ
ESVCVATASGDVILCSLSTQQLECVGSVASGISVMSWSPDQELVLLATGQQTLIMMTKDFEPILEQQIHQDDFGESKFITVGWGRKETQF
HGSEGRQAAFQMQMHESALPWDDHRPQVTWRGDGQFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGLGPALAWKPSGSLIASTQDKP
NQQDIVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSVLAVWLEDLQREESSIPKTCVQLWTVGNYHWYLKQSLSFSTCGKSKIVSLM
WDPVTPYRLHVLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDLA

--------------------------------------------------------------
>39361_39361_5_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000374647_PTPN3_chr9_112153841_ENST00000446349_length(transcript)=6319nt_BP=1668nt
AGTGCTGCGGCTGCCTAGTTGACGCACCCATTGAGTCGCTGGCTTCTTTGCAGCGCTTCAGCGTTTTCCCCTGGAGGGCGCCTCCATCCT
TGGAGGCCTAGTGCCGTCGGAGAGAGAGCGGGAGCCGCGGACAGAGACGCGTGCGCAATTCGGAGCCGACTCTGGGTGCGGACTGTGGGA
GCTGACTCTGGGTAGCCGGCTGCGCGTGGCTGGGGAGGCGAGGCCGGACGCACCTCTGTTTGGGGGTCCTCAGAGATTAATGATTCATCA
AGGGATAGTTGTACTTGTCTCGTGGGAATCACTTCATCATGCGAAATCTGAAATTATTTCGGACCCTGGAGTTCAGGGATATTCAAGGTC
CAGGGAATCCTCAGTGCTTCTCTCTCCGAACTGAACAGGGGACGGTGCTCATTGGTTCAGAACATGGCCTGATAGAAGTAGACCCTGTCT
CAAGAGAAGTGAAAAATGAAGTTTCTTTGGTGGCAGAAGGCTTTCTCCCAGAGGATGGAAGTGGCCGCATTGTTGGTGTTCAGGACTTGC
TGGATCAGGAGTCTGTGTGTGTGGCCACAGCCTCTGGAGACGTCATACTCTGCAGTCTCAGCACACAACAGCTGGAGTGTGTTGGGAGTG
TAGCCAGTGGTATCTCTGTTATGAGTTGGAGTCCTGACCAAGAGCTGGTGCTTCTTGCCACAGGTCAACAGACCCTGATTATGATGACAA
AAGATTTTGAGCCAATCCTGGAGCAGCAGATCCATCAGGATGATTTTGGTGAAAGCAAGTTTATCACTGTTGGATGGGGTAGGAAGGAGA
CACAGTTCCATGGATCAGAAGGCAGACAAGCAGCTTTTCAGATGCAAATGCATGAGTCTGCTTTGCCCTGGGATGACCATAGACCACAAG
TTACCTGGCGGGGGGATGGACAGTTTTTTGCTGTGAGTGTTGTTTGCCCAGAAACAGGGGCTCGGAAGGTCAGAGTGTGGAACCGAGAGT
TTGCTTTGCAGTCAACCAGTGAGCCTGTGGCAGGACTGGGACCAGCCCTGGCTTGGAAACCCTCAGGCAGTTTGATTGCATCTACACAAG
ATAAACCCAACCAGCAGGATATTGTGTTTTTTGAGAAAAATGGACTCCTTCATGGACACTTTACACTTCCCTTCCTTAAAGATGAGGTTA
AGGTAAATGACTTGCTCTGGAATGCAGATTCCTCTGTGCTTGCAGTCTGGCTGGAAGACCTTCAGAGAGAAGAAAGCTCCATTCCGAAAA
CCTGTGTTCAGCTCTGGACTGTTGGAAACTATCACTGGTATCTCAAGCAAAGTTTATCCTTCAGCACCTGTGGGAAGAGCAAGATTGTGT
CTCTGATGTGGGACCCTGTGACCCCATACCGGCTGCATGTTCTCTGTCAGGGCTGGCATTACCTCGCCTATGATTGGCACTGGACGACTG
ACCGGAGCGTGGGAGATAATTCAAGTGACTTGTCCAATGTGGCTGTCATTGATGGAAACAGGGTGTTGGTGACAGTCTTCCGGCAGACTG
TGGTTCCGCCTCCCATGTGCACCTACCAACTGCTGTTCCCACACCCTGTGAATCAAGTCACATTCTTAGCACACCCTCAAAAGAGTAATG
ACCTTGCTGTTCTAGATGCCAGTAACCAGATTTCTGTTTATAAATGTGCAACTCTACAGAAAAAAGCCAGGTTTGGCCATCACGTTTGCA
AAGCTGCCTCAAAATTTGGACAAAAACCGATATAAAGATGTGCTGCCTTATGACACCACCCGGGTATTATTGCAGGGAAATGAAGATTAT
ATTAATGCAAGTTACGTGAACATGGAAATTCCTGCTGCTAACCTTGTGAACAAGTACATCGCCACTCAGGGGCCCCTGCCGCATACCTGT
GCACAGTTTTGGCAGGTTGTCTGGGATCAGAAGTTGTCACTCATTGTCATGTTGACGACTCTCACAGAACGAGGGCGGACCAAATGTCAC
CAGTACTGGCCAGATCCCCCCGACGTCATGAACCACGGCGGCTTTCACATCCAGTGTCAGTCAGAGGACTGCACCATCGCCTATGTGTCC
CGAGAAATGCTGGTCACAAACACCCAGACCGGGGAAGAACACACAGTGACACATCTCCAGTACGTCGCATGGCCTGACCACGGTGTGCCC
GATGACTCCTCCGACTTTCTGGAATTTGTAAACTATGTGAGGTCTCTGAGAGTGGACAGCGAGCCCGTCCTAGTTCACTGCAGTGCTGGA
ATAGGTCGAACCGGTGTGTTGGTCACTATGGAAACAGCCATGTGCCTAACTGAGAGGAACCTGCCCATTTACCCACTGGATATTGTCCGA
AAAATGCGAGACCAGCGCGCCATGATGGTGCAGACATCAAGCCAGTACAAGTTTGTGTGTGAAGCGATTCTTCGTGTGTATGAAGAAGGT
TTAGTCCAAATGCTGGATCCTAGTTAAGACAACTGTGAAAAAGTTCATTCCTCTTTCCCAAGGGCATCCTCCTTGAAAGAGGAGGACAGA
CCTCTCTGGAAGCAGCAAGAGGAACCAGTAGCTGTGGGAAAGGAATGGGCACCTCTGAACCCAGGCACTTTAAACTTCTATAGAAAAGAT
ATCGTGTACATAGGAACTGGTGTAGATAAGCATGCAATTATGGCATCATTTAGGCCTGTATTTCTATGGAAAGATACAAAAAGGATCTCA
GTTTGGGGCCTGTCCTAATGCCTTCTTCCCTAACATCACCACACACACCCCTGTCGGCATCCTGGAGCAATTGAGACCGGACACCCACAG
AGCTGTTGTCCTCCCAGCAACAAGATGGTGTGGTTATCTTGGGTCATTTGGATGTTTTGTTTGTTTCTGTGTGTCAGACTGTAAGGGCTG
AGCTTTCTGTGCTTCTAGGTGGAGCTGGAACAATTCAGATTCACCCGCCCTGATGCTAAGGAAACCCTGACGTATGTACTAGATGGCAGG
GCACTGGGGGTCAGGCTGAAGGCTGAGCAACACCTCTCTGCCCTCCCTCCCTTTGTCCCATCTCCCAGCGACTTCCAATATTCATGTTTC
TGAGAATTGTGTCCCTCTTCAGGTTCCCTCTTGGTGCCTAACCTGGATTAGTAATGTGCATTCAGGTGAATTTTCAGCTGAGGCTCTGAG
AACTGGTACTCTCAGTGTGTTCTGGTCATCTTGTGGCTTAGTTGTAGAAGCAGGTGTGTCTCTTGCCTCTGCTTGCCTCCTACTGCACAC
TCAGCACCCAGGACTGGAATCACCGACTACTGAATCTCCTACATGTATTGCTGCTACTTCAAGCTCCTCCACTTGAAACCTTATGATTTT
CCCAAGGGGAGATGGGACAGTGTCATCTAAATATTCCGAATGTTTGGCCTTCTGAGAAAAGAGCTTCTAGTAATTGAACCATGGGAAACC
CAGCTTCTGGAGGGTTGGCCGTGGGGCTGTGTACATGTGTGTGCCCAGGGGTGAGTGTTTCTCAGGATTCCTAACGATTCAAATTACCGT
TGAGTATATATAAAGAATGAGTCTCTGTATGGAAGAACAAATGTGTGCATTCACCCCCAGTCACAATGGTCTCCATTGCATTTCAAAGGA
GAGGATCAGACTATCTGAATATAAACACAATCTGATGTTAATTTATTCTAAGAACACCATCATTTTGATTGTCCTAAAGAATTCTGCCTT
TGTGAATACCGTGTTAAATTTTTTTAAATTTGTGACAGGATTGTAGCAAATTATTATTTAAGGAAAATAAATTGTGTAAACATTTAATGT
GGTATTTTTGAACAGCGGTTTTTATGTACTCAGAAGAGGAAGTAAAGCCAGGTTCTTAATGGTATTTATAGAAAAGATGTTTTCATATTA
TAATGCACATAAATGAAGCCATTTTGATATTCAGCAAATTCGGTGCCAATTGAATAGTTTGCTGGTAGCAAGACGGATGAAGACCTATAT
GGGAGATTCTTTATCTCTAGAGCTAGCATATTTACTTGCATACTTTGTTTCTTTTCCACATGGATATTTTACTGCTAAATGGCAGAGGTG
GGAGGGAGATGTCACACAGTACCATAACCCCATATTGAAAACAAGAAACCACCAGAAAGTTTGCAGCTAAGGGGCAGGGGATTCAGTTCC
TACGCCCACTCAGCACTAACTACTTGCGGGCCTGGTTGCTTAGAAGCTCTACCTCTCTTTCATTATCTGTAAAATAGAAACAATACTTAG
GACTTTAGTTGGAACATGAGGATTGAATAAGATCACGCTATTCATGTGACTTTTTATCGGCTAGAACAGCAACAGACACTGCTGTGGGTG
AGTTACTTAGAAAAGTTTAGTTATCAGTGATTAGCCCAAAAACACATCAGTCAAAAATAGAATCCACTGGATTTTTGTCTCTCTTTTTAG
AGACAGGGTCTCACTGTCGCCCAGGCTGGAGTACAGTGGCATGATCATTGTTCACTGCAGCCTCAAATTCCTGGGCTCAAGCAATCCTCG
CACCTCAGCCTCCTGAGTAGCCGGGACTATAGGCACATGCCACCTCACCTGGCTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTAGAGACAGGATCTTGATGTGTTGCCTAGGCTGGTCTCAAACTCCTGGCCTCAAGTGATCTTCC
CACCTCAGCCTCCAAAACTGTTGGGATTATAGGCGTGAGCCACTGTGCCCAGCCTAACTGGGTTTTTATGAGAGGAAAATAGAAAATGCT
CTTCTAGAAGAGAGAGAACAAGAGCACAAAATAATCTGGACTCACAAAAATTCAGCAAGCTCCAAGAAAGGGGGATGGAGGGAACGCTGG
CAAAAATTTAAATGCCATTAGGATATTTAGCAAGTTATTACTGTTTGGTAAAAATGCATCATCACCCTGTGTGCAAAATGCTTGCAAAGT
AGTCTAAATGTCTTTGGAGATGGGTGTTTTACTGCTTTTTTCCAAAAACAAATTGTTTATTATGGTTGCAGAAATGCAGCCATTACGGTC
ACATAAATTTCTAAAAAGCCTACCAAAGGTTGCAAGCAGTCTTCTGCCACTGGGCAGGCCAGCAGTTCAGACCCAGCGAGGTTGCCAGGA
ACAAATCCAGGAAATACTGGGAAGAACAAGACAAGAGAATTACCTAAAAGAGCAAACAATTCAAGTAAATCCTGTAGCTATTACCACTTA
AAATCCGTAGCTCAAGATTCCTGTTTCACCACCTTATACACTTAAGCAATTATACTTAAGCCTTTTTTTAGTCCTAAGTGAAGAACTACA
TCAGAATCAGGATAAGTATTTTGCCTGGGAAATTTGGCTGCATATGAATGGAGAAGACATTTACATCCTATGTTCTGGCACTTTCTGAAA
GATCTAATTAAACATGTTGATGTGCCAATTTAATCAAGATGAGAGATCCCTGCTGGTGTCACCCTCTAGAACCTGCACTTGGTGTTTTGA
CTTTCCAGAAGAAAAAAATGCAACTTTGGTTAGGGGGCAGTGGTTGGATCACACAGTTGTCTTTCGTTTCCTACCACAGTAATTCATATT
TAAATATGCTTTTAGATTAGTGTGGATACTATTGCTGCTGTGTTGCTACCTGACCTTTTTCTGGGGGGGGTACCTCAGAAATGAGCATTT
GAGGGCAAGCGAAAAAGCCCTCTTCATCCTCCAGAGGCAACAAAGAGGCAGCAGAAATGGGGAAAGATTGTGAGAGGCAGGGCTTGGGTC
TAGACCTGGACTTAGGCAAGATATGTTGCCCTCAACCCTGAGTTTTCTTATATGTAAAAAGGGAAGGTTGGGCTGGACTAGATGAGGTCA
AGATTTGCCATTCTGGGAGGCTGATATTCCAGAGAATCAAAATTAATCCTAAACCAAAGCTTTATGGCTGCTACAGAGACATGTCACATT
TCTGAGACTTGTCACCAAGAGTTTGTCCCTCAGACTTTGGCGCTGTTGAATGCAAAGACAAGGATGGCCACCTTCTGGTTCTTGCCTGTT
GTCCTCAGCTGAGAGCAGTCTCGGTAAAGGTGGCAAAGATTCTGTGACCTCAGACCGGGGACCAAATGCTTGGGAGTCTGATGGCCGGGC
TGGGCCACCATTCTCATAGCTCTCATTCTGTTTGGAGCAACCAAAGGATTTGTGTGAAGTTATTTGGAAAAGGACCTTAACTGAGCAGTA
ATCTTTTTTCTGTATATTTGGAATGTTTTTCATTCTGACCTGTTCTGTCAGTGATTCTACTGAAAAACAATTTAATCAATATAAAAATGT

>39361_39361_5_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000374647_PTPN3_chr9_112153841_ENST00000446349_length(amino acids)=488AA_BP=463
MYLSRGNHFIMRNLKLFRTLEFRDIQGPGNPQCFSLRTEQGTVLIGSEHGLIEVDPVSREVKNEVSLVAEGFLPEDGSGRIVGVQDLLDQ
ESVCVATASGDVILCSLSTQQLECVGSVASGISVMSWSPDQELVLLATGQQTLIMMTKDFEPILEQQIHQDDFGESKFITVGWGRKETQF
HGSEGRQAAFQMQMHESALPWDDHRPQVTWRGDGQFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGLGPALAWKPSGSLIASTQDKP
NQQDIVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSVLAVWLEDLQREESSIPKTCVQLWTVGNYHWYLKQSLSFSTCGKSKIVSLM
WDPVTPYRLHVLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDLA

--------------------------------------------------------------
>39361_39361_6_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000537196_PTPN3_chr9_112153841_ENST00000262539_length(transcript)=1683nt_BP=710nt
GGGTGCGGACTGTGGGAGCTGACTCTGGGTAGCCGGCTGCGCGTGGCTGGGGAGGCGAGGCCGGACGCACCTCTGTTTGGGGGTCCTCAG
ACCCTCAGGCAGTTTGATTGCATCTACACAAGATAAACCCAACCAGCAGGATATTGTGTTTTTTGAGAAAAATGGACTCCTTCATGGACA
CTTTACACTTCCCTTCCTTAAAGATGAGGTTAAGGTAAATGACTTGCTCTGGAATGCAGATTCCTCTGTGCTTGCAGTCTGGCTGGAAGA
CCTTCAGAGAGAAGAAAGCTCCATTCCGAAAACCTGTGTTCAGCTCTGGACTGTTGGAAACTATCACTGGTATCTCAAGCAAAGTTTATC
CTTCAGCACCTGTGGGAAGAGCAAGATTGTGTCTCTGATGTGGGACCCTGTGACCCCATACCGGCTGCATGTTCTCTGTCAGGGCTGGCA
TTACCTCGCCTATGATTGGCACTGGACGACTGACCGGAGCGTGGGAGATAATTCAAGTGACTTGTCCAATGTGGCTGTCATTGATGGAAA
CAGGGTGTTGGTGACAGTCTTCCGGCAGACTGTGGTTCCGCCTCCCATGTGCACCTACCAACTGCTGTTCCCACACCCTGTGAATCAAGT
CACATTCTTAGCACACCCTCAAAAGAGTAATGACCTTGCTGTTCTAGATGCCAGTAACCAGATTTCTGTTTATAAATGTGCAACTCTACA
GAAAAAAGCCAGGTTTGGCCATCACGTTTGCAAAGCTGCCTCAAAATTTGGACAAAAACCGATATAAAGATGTGCTGCCTTATGACACCA
CCCGGGTATTATTGCAGGGAAATGAAGATTATATTAATGCAAGTTACGTGAACATGGAAATTCCTGCTGCTAACCTTGTGAACAAGTACA
TCGCCACTCAGGGGCCCCTGCCGCATACCTGTGCACAGTTTTGGCAGGTTGTCTGGGATCAGAAGTTGTCACTCATTGTCATGTTGACGA
CTCTCACAGAACGAGGGCGGACCAAATGTCACCAGTACTGGCCAGATCCCCCCGACGTCATGAACCACGGCGGCTTTCACATCCAGTGTC
AGTCAGAGGACTGCACCATCGCCTATGTGTCCCGAGAAATGCTGGTCACAAACACCCAGACCGGGGAAGAACACACAGTGACACATCTCC
AGTACGTCGCATGGCCTGACCACGGTGTGCCCGATGACTCCTCCGACTTTCTGGAATTTGTAAACTATGTGAGGTCTCTGAGAGTGGACA
GCGAGCCCGTCCTAGTTCACTGCAGTGCTGGAATAGGTCGAACCGGTGTGTTGGTCACTATGGAAACAGCCATGTGCCTAACTGAGAGGA
ACCTGCCCATTTACCCACTGGATATTGTCCGAAAAATGCGAGACCAGCGCGCCATGATGGTGCAGACATCAAGCCAGTACAAGTTTGTGT
GTGAAGCGATTCTTCGTGTGTATGAAGAAGGTTTAGTCCAAATGCTGGATCCTAGTTAAGACAACTGTGAAAAAGTTCATTCCTCTTTCC
CAAGGGCATCCTCCTTGAAAGAGGAGGACAGACCTCTCTGGAAGCAGCAAGAGGAACCAGTAGCTGTGGGAAAGGAATGGGCACCTCTGA

>39361_39361_6_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000537196_PTPN3_chr9_112153841_ENST00000262539_length(amino acids)=273AA_BP=6
MPVTRFLFINVQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQ
VVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSD
FLEFVNYVRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQML

--------------------------------------------------------------
>39361_39361_7_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000537196_PTPN3_chr9_112153841_ENST00000374541_length(transcript)=5355nt_BP=710nt
GGGTGCGGACTGTGGGAGCTGACTCTGGGTAGCCGGCTGCGCGTGGCTGGGGAGGCGAGGCCGGACGCACCTCTGTTTGGGGGTCCTCAG
ACCCTCAGGCAGTTTGATTGCATCTACACAAGATAAACCCAACCAGCAGGATATTGTGTTTTTTGAGAAAAATGGACTCCTTCATGGACA
CTTTACACTTCCCTTCCTTAAAGATGAGGTTAAGGTAAATGACTTGCTCTGGAATGCAGATTCCTCTGTGCTTGCAGTCTGGCTGGAAGA
CCTTCAGAGAGAAGAAAGCTCCATTCCGAAAACCTGTGTTCAGCTCTGGACTGTTGGAAACTATCACTGGTATCTCAAGCAAAGTTTATC
CTTCAGCACCTGTGGGAAGAGCAAGATTGTGTCTCTGATGTGGGACCCTGTGACCCCATACCGGCTGCATGTTCTCTGTCAGGGCTGGCA
TTACCTCGCCTATGATTGGCACTGGACGACTGACCGGAGCGTGGGAGATAATTCAAGTGACTTGTCCAATGTGGCTGTCATTGATGGAAA
CAGGGTGTTGGTGACAGTCTTCCGGCAGACTGTGGTTCCGCCTCCCATGTGCACCTACCAACTGCTGTTCCCACACCCTGTGAATCAAGT
CACATTCTTAGCACACCCTCAAAAGAGTAATGACCTTGCTGTTCTAGATGCCAGTAACCAGATTTCTGTTTATAAATGTGCAACTCTACA
GAAAAAAGCCAGGTTTGGCCATCACGTTTGCAAAGCTGCCTCAAAATTTGGACAAAAACCGATATAAAGATGTGCTGCCTTATGACACCA
CCCGGGTATTATTGCAGGGAAATGAAGATTATATTAATGCAAGTTACGTGAACATGGAAATTCCTGCTGCTAACCTTGTGAACAAGTACA
TCGCCACTCAGGGGCCCCTGCCGCATACCTGTGCACAGTTTTGGCAGGTTGTCTGGGATCAGAAGTTGTCACTCATTGTCATGTTGACGA
CTCTCACAGAACGAGGGCGGACCAAATGTCACCAGTACTGGCCAGATCCCCCCGACGTCATGAACCACGGCGGCTTTCACATCCAGTGTC
AGTCAGAGGACTGCACCATCGCCTATGTGTCCCGAGAAATGCTGGTCACAAACACCCAGACCGGGGAAGAACACACAGTGACACATCTCC
AGTACGTCGCATGGCCTGACCACGGTGTGCCCGATGACTCCTCCGACTTTCTGGAATTTGTAAACTATGTGAGGTCTCTGAGAGTGGACA
GCGAGCCCGTCCTAGTTCACTGCAGTGCTGGAATAGGTCGAACCGGTGTGTTGGTCACTATGGAAACAGCCATGTGCCTAACTGAGAGGA
ACCTGCCCATTTACCCACTGGATATTGTCCGAAAAATGCGAGACCAGCGCGCCATGATGGTGCAGACATCAAGCCAGTACAAGTTTGTGT
GTGAAGCGATTCTTCGTGTGTATGAAGAAGGTTTAGTCCAAATGCTGGATCCTAGTTAAGACAACTGTGAAAAAGTTCATTCCTCTTTCC
CAAGGGCATCCTCCTTGAAAGAGGAGGACAGACCTCTCTGGAAGCAGCAAGAGGAACCAGTAGCTGTGGGAAAGGAATGGGCACCTCTGA
ACCCAGGCACTTTAAACTTCTATAGAAAAGATATCGTGTACATAGGAACTGGTGTAGATAAGCATGCAATTATGGCATCATTTAGGCCTG
TATTTCTATGGAAAGATACAAAAAGGATCTCAGTTTGGGGCCTGTCCTAATGCCTTCTTCCCTAACATCACCACACACACCCCTGTCGGC
ATCCTGGAGCAATTGAGACCGGACACCCACAGAGCTGTTGTCCTCCCAGCAACAAGATGGTGTGGTTATCTTGGGTCATTTGGATGTTTT
GTTTGTTTCTGTGTGTCAGACTGTAAGGGCTGAGCTTTCTGTGCTTCTAGGTGGAGCTGGAACAATTCAGATTCACCCGCCCTGATGCTA
AGGAAACCCTGACGTATGTACTAGATGGCAGGGCACTGGGGGTCAGGCTGAAGGCTGAGCAACACCTCTCTGCCCTCCCTCCCTTTGTCC
CATCTCCCAGCGACTTCCAATATTCATGTTTCTGAGAATTGTGTCCCTCTTCAGGTTCCCTCTTGGTGCCTAACCTGGATTAGTAATGTG
CATTCAGGTGAATTTTCAGCTGAGGCTCTGAGAACTGGTACTCTCAGTGTGTTCTGGTCATCTTGTGGCTTAGTTGTAGAAGCAGGTGTG
TCTCTTGCCTCTGCTTGCCTCCTACTGCACACTCAGCACCCAGGACTGGAATCACCGACTACTGAATCTCCTACATGTATTGCTGCTACT
TCAAGCTCCTCCACTTGAAACCTTATGATTTTCCCAAGGGGAGATGGGACAGTGTCATCTAAATATTCCGAATGTTTGGCCTTCTGAGAA
AAGAGCTTCTAGTAATTGAACCATGGGAAACCCAGCTTCTGGAGGGTTGGCCGTGGGGCTGTGTACATGTGTGTGCCCAGGGGTGAGTGT
TTCTCAGGATTCCTAACGATTCAAATTACCGTTGAGTATATATAAAGAATGAGTCTCTGTATGGAAGAACAAATGTGTGCATTCACCCCC
AGTCACAATGGTCTCCATTGCATTTCAAAGGAGAGGATCAGACTATCTGAATATAAACACAATCTGATGTTAATTTATTCTAAGAACACC
ATCATTTTGATTGTCCTAAAGAATTCTGCCTTTGTGAATACCGTGTTAAATTTTTTTAAATTTGTGACAGGATTGTAGCAAATTATTATT
TAAGGAAAATAAATTGTGTAAACATTTAATGTGGTATTTTTGAACAGCGGTTTTTATGTACTCAGAAGAGGAAGTAAAGCCAGGTTCTTA
ATGGTATTTATAGAAAAGATGTTTTCATATTATAATGCACATAAATGAAGCCATTTTGATATTCAGCAAATTCGGTGCCAATTGAATAGT
TTGCTGGTAGCAAGACGGATGAAGACCTATATGGGAGATTCTTTATCTCTAGAGCTAGCATATTTACTTGCATACTTTGTTTCTTTTCCA
CATGGATATTTTACTGCTAAATGGCAGAGGTGGGAGGGAGATGTCACACAGTACCATAACCCCATATTGAAAACAAGAAACCACCAGAAA
GTTTGCAGCTAAGGGGCAGGGGATTCAGTTCCTACGCCCACTCAGCACTAACTACTTGCGGGCCTGGTTGCTTAGAAGCTCTACCTCTCT
TTCATTATCTGTAAAATAGAAACAATACTTAGGACTTTAGTTGGAACATGAGGATTGAATAAGATCACGCTATTCATGTGACTTTTTATC
GGCTAGAACAGCAACAGACACTGCTGTGGGTGAGTTACTTAGAAAAGTTTAGTTATCAGTGATTAGCCCAAAAACACATCAGTCAAAAAT
AGAATCCACTGGATTTTTGTCTCTCTTTTTAGAGACAGGGTCTCACTGTCGCCCAGGCTGGAGTACAGTGGCATGATCATTGTTCACTGC
AGCCTCAAATTCCTGGGCTCAAGCAATCCTCGCACCTCAGCCTCCTGAGTAGCCGGGACTATAGGCACATGCCACCTCACCTGGCTTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAGAGACAGGATCTTGATGTGTTGCCTAGGCT
GGTCTCAAACTCCTGGCCTCAAGTGATCTTCCCACCTCAGCCTCCAAAACTGTTGGGATTATAGGCGTGAGCCACTGTGCCCAGCCTAAC
TGGGTTTTTATGAGAGGAAAATAGAAAATGCTCTTCTAGAAGAGAGAGAACAAGAGCACAAAATAATCTGGACTCACAAAAATTCAGCAA
GCTCCAAGAAAGGGGGATGGAGGGAACGCTGGCAAAAATTTAAATGCCATTAGGATATTTAGCAAGTTATTACTGTTTGGTAAAAATGCA
TCATCACCCTGTGTGCAAAATGCTTGCAAAGTAGTCTAAATGTCTTTGGAGATGGGTGTTTTACTGCTTTTTTCCAAAAACAAATTGTTT
ATTATGGTTGCAGAAATGCAGCCATTACGGTCACATAAATTTCTAAAAAGCCTACCAAAGGTTGCAAGCAGTCTTCTGCCACTGGGCAGG
CCAGCAGTTCAGACCCAGCGAGGTTGCCAGGAACAAATCCAGGAAATACTGGGAAGAACAAGACAAGAGAATTACCTAAAAGAGCAAACA
ATTCAAGTAAATCCTGTAGCTATTACCACTTAAAATCCGTAGCTCAAGATTCCTGTTTCACCACCTTATACACTTAAGCAATTATACTTA
AGCCTTTTTTTAGTCCTAAGTGAAGAACTACATCAGAATCAGGATAAGTATTTTGCCTGGGAAATTTGGCTGCATATGAATGGAGAAGAC
ATTTACATCCTATGTTCTGGCACTTTCTGAAAGATCTAATTAAACATGTTGATGTGCCAATTTAATCAAGATGAGAGATCCCTGCTGGTG
TCACCCTCTAGAACCTGCACTTGGTGTTTTGACTTTCCAGAAGAAAAAAATGCAACTTTGGTTAGGGGGCAGTGGTTGGATCACACAGTT
GTCTTTCGTTTCCTACCACAGTAATTCATATTTAAATATGCTTTTAGATTAGTGTGGATACTATTGCTGCTGTGTTGCTACCTGACCTTT
TTCTGGGGGGGGTACCTCAGAAATGAGCATTTGAGGGCAAGCGAAAAAGCCCTCTTCATCCTCCAGAGGCAACAAAGAGGCAGCAGAAAT
GGGGAAAGATTGTGAGAGGCAGGGCTTGGGTCTAGACCTGGACTTAGGCAAGATATGTTGCCCTCAACCCTGAGTTTTCTTATATGTAAA
AAGGGAAGGTTGGGCTGGACTAGATGAGGTCAAGATTTGCCATTCTGGGAGGCTGATATTCCAGAGAATCAAAATTAATCCTAAACCAAA
GCTTTATGGCTGCTACAGAGACATGTCACATTTCTGAGACTTGTCACCAAGAGTTTGTCCCTCAGACTTTGGCGCTGTTGAATGCAAAGA
CAAGGATGGCCACCTTCTGGTTCTTGCCTGTTGTCCTCAGCTGAGAGCAGTCTCGGTAAAGGTGGCAAAGATTCTGTGACCTCAGACCGG
GGACCAAATGCTTGGGAGTCTGATGGCCGGGCTGGGCCACCATTCTCATAGCTCTCATTCTGTTTGGAGCAACCAAAGGATTTGTGTGAA
GTTATTTGGAAAAGGACCTTAACTGAGCAGTAATCTTTTTTCTGTATATTTGGAATGTTTTTCATTCTGACCTGTTCTGTCAGTGATTCT

>39361_39361_7_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000537196_PTPN3_chr9_112153841_ENST00000374541_length(amino acids)=273AA_BP=6
MPVTRFLFINVQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQ
VVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSD
FLEFVNYVRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQML

--------------------------------------------------------------
>39361_39361_8_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000537196_PTPN3_chr9_112153841_ENST00000394827_length(transcript)=1968nt_BP=710nt
GGGTGCGGACTGTGGGAGCTGACTCTGGGTAGCCGGCTGCGCGTGGCTGGGGAGGCGAGGCCGGACGCACCTCTGTTTGGGGGTCCTCAG
ACCCTCAGGCAGTTTGATTGCATCTACACAAGATAAACCCAACCAGCAGGATATTGTGTTTTTTGAGAAAAATGGACTCCTTCATGGACA
CTTTACACTTCCCTTCCTTAAAGATGAGGTTAAGGTAAATGACTTGCTCTGGAATGCAGATTCCTCTGTGCTTGCAGTCTGGCTGGAAGA
CCTTCAGAGAGAAGAAAGCTCCATTCCGAAAACCTGTGTTCAGCTCTGGACTGTTGGAAACTATCACTGGTATCTCAAGCAAAGTTTATC
CTTCAGCACCTGTGGGAAGAGCAAGATTGTGTCTCTGATGTGGGACCCTGTGACCCCATACCGGCTGCATGTTCTCTGTCAGGGCTGGCA
TTACCTCGCCTATGATTGGCACTGGACGACTGACCGGAGCGTGGGAGATAATTCAAGTGACTTGTCCAATGTGGCTGTCATTGATGGAAA
CAGGGTGTTGGTGACAGTCTTCCGGCAGACTGTGGTTCCGCCTCCCATGTGCACCTACCAACTGCTGTTCCCACACCCTGTGAATCAAGT
CACATTCTTAGCACACCCTCAAAAGAGTAATGACCTTGCTGTTCTAGATGCCAGTAACCAGATTTCTGTTTATAAATGTGCAACTCTACA
GAAAAAAGCCAGGTTTGGCCATCACGTTTGCAAAGCTGCCTCAAAATTTGGACAAAAACCGATATAAAGATGTGCTGCCTTATGACACCA
CCCGGGTATTATTGCAGGGAAATGAAGATTATATTAATGCAAGTTACGTGAACATGGAAATTCCTGCTGCTAACCTTGTGAACAAGTACA
TCGCCACTCAGGGGCCCCTGCCGCATACCTGTGCACAGTTTTGGCAGGTTGTCTGGGATCAGAAGTTGTCACTCATTGTCATGTTGACGA
CTCTCACAGAACGAGGGCGGACCAAATGTCACCAGTACTGGCCAGATCCCCCCGACGTCATGAACCACGGCGGCTTTCACATCCAGTGTC
AGTCAGAGGACTGCACCATCGCCTATGTGTCCCGAGAAATGCTGGTCACAAACACCCAGACCGGGGAAGAACACACAGTGACACATCTCC
AGTACGTCGCATGGCCTGACCACGGTGTGCCCGATGACTCCTCCGACTTTCTGGAATTTGTAAACTATGTGAGGTCTCTGAGAGTGGACA
GCGAGCCCGTCCTAGTTCACTGCAGTGCTGGAATAGGTCGAACCGGTGTGTTGGTCACTATGGAAACAGCCATGTGCCTAACTGAGAGGA
ACCTGCCCATTTACCCACTGGATATTGTCCGAAAAATGCGAGACCAGCGCGCCATGATGGTGCAGACATCAAGCCAGTACAAGTTTGTGT
GTGAAGCGATTCTTCGTGTGTATGAAGAAGGTTTAGTCCAAATGCTGGATCCTAGTTAAGACAACTGTGAAAAAGTTCATTCCTCTTTCC
CAAGGGCATCCTCCTTGAAAGAGGAGGACAGACCTCTCTGGAAGCAGCAAGAGGAACCAGTAGCTGTGGGAAAGGAATGGGCACCTCTGA
ACCCAGGCACTTTAAACTTCTATAGAAAAGATATCGTGTACATAGGAACTGGTGTAGATAAGCATGCAATTATGGCATCATTTAGGCCTG
TATTTCTATGGAAAGATACAAAAAGGATCTCAGTTTGGGGCCTGTCCTAATGCCTTCTTCCCTAACATCACCACACACACCCCTGTCGGC
ATCCTGGAGCAATTGAGACCGGACACCCACAGAGCTGTTGTCCTCCCAGCAACAAGATGGTGTGGTTATCTTGGGTCATTTGGATGTTTT

>39361_39361_8_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000537196_PTPN3_chr9_112153841_ENST00000394827_length(amino acids)=273AA_BP=6
MPVTRFLFINVQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQ
VVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSD
FLEFVNYVRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQML

--------------------------------------------------------------
>39361_39361_9_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000537196_PTPN3_chr9_112153841_ENST00000412145_length(transcript)=5361nt_BP=710nt
GGGTGCGGACTGTGGGAGCTGACTCTGGGTAGCCGGCTGCGCGTGGCTGGGGAGGCGAGGCCGGACGCACCTCTGTTTGGGGGTCCTCAG
ACCCTCAGGCAGTTTGATTGCATCTACACAAGATAAACCCAACCAGCAGGATATTGTGTTTTTTGAGAAAAATGGACTCCTTCATGGACA
CTTTACACTTCCCTTCCTTAAAGATGAGGTTAAGGTAAATGACTTGCTCTGGAATGCAGATTCCTCTGTGCTTGCAGTCTGGCTGGAAGA
CCTTCAGAGAGAAGAAAGCTCCATTCCGAAAACCTGTGTTCAGCTCTGGACTGTTGGAAACTATCACTGGTATCTCAAGCAAAGTTTATC
CTTCAGCACCTGTGGGAAGAGCAAGATTGTGTCTCTGATGTGGGACCCTGTGACCCCATACCGGCTGCATGTTCTCTGTCAGGGCTGGCA
TTACCTCGCCTATGATTGGCACTGGACGACTGACCGGAGCGTGGGAGATAATTCAAGTGACTTGTCCAATGTGGCTGTCATTGATGGAAA
CAGGGTGTTGGTGACAGTCTTCCGGCAGACTGTGGTTCCGCCTCCCATGTGCACCTACCAACTGCTGTTCCCACACCCTGTGAATCAAGT
CACATTCTTAGCACACCCTCAAAAGAGTAATGACCTTGCTGTTCTAGATGCCAGTAACCAGATTTCTGTTTATAAATGTGCAACTCTACA
GAAAAAAGCCAGGTTTGGCCATCACGTTTGCAAAGCTGCCTCAAAATTTGGACAAAAACCGATATAAAGATGTGCTGCCTTATGACACCA
CCCGGGTATTATTGCAGGGAAATGAAGATTATATTAATGCAAGTTACGTGAACATGGAAATTCCTGCTGCTAACCTTGTGAACAAGTACA
TCGCCACTCAGGGGCCCCTGCCGCATACCTGTGCACAGTTTTGGCAGGTTGTCTGGGATCAGAAGTTGTCACTCATTGTCATGTTGACGA
CTCTCACAGAACGAGGGCGGACCAAATGTCACCAGTACTGGCCAGATCCCCCCGACGTCATGAACCACGGCGGCTTTCACATCCAGTGTC
AGTCAGAGGACTGCACCATCGCCTATGTGTCCCGAGAAATGCTGGTCACAAACACCCAGACCGGGGAAGAACACACAGTGACACATCTCC
AGTACGTCGCATGGCCTGACCACGGTGTGCCCGATGACTCCTCCGACTTTCTGGAATTTGTAAACTATGTGAGGTCTCTGAGAGTGGACA
GCGAGCCCGTCCTAGTTCACTGCAGTGCTGGAATAGGTCGAACCGGTGTGTTGGTCACTATGGAAACAGCCATGTGCCTAACTGAGAGGA
ACCTGCCCATTTACCCACTGGATATTGTCCGAAAAATGCGAGACCAGCGCGCCATGATGGTGCAGACATCAAGCCAGTACAAGTTTGTGT
GTGAAGCGATTCTTCGTGTGTATGAAGAAGGTTTAGTCCAAATGCTGGATCCTAGTTAAGACAACTGTGAAAAAGTTCATTCCTCTTTCC
CAAGGGCATCCTCCTTGAAAGAGGAGGACAGACCTCTCTGGAAGCAGCAAGAGGAACCAGTAGCTGTGGGAAAGGAATGGGCACCTCTGA
ACCCAGGCACTTTAAACTTCTATAGAAAAGATATCGTGTACATAGGAACTGGTGTAGATAAGCATGCAATTATGGCATCATTTAGGCCTG
TATTTCTATGGAAAGATACAAAAAGGATCTCAGTTTGGGGCCTGTCCTAATGCCTTCTTCCCTAACATCACCACACACACCCCTGTCGGC
ATCCTGGAGCAATTGAGACCGGACACCCACAGAGCTGTTGTCCTCCCAGCAACAAGATGGTGTGGTTATCTTGGGTCATTTGGATGTTTT
GTTTGTTTCTGTGTGTCAGACTGTAAGGGCTGAGCTTTCTGTGCTTCTAGGTGGAGCTGGAACAATTCAGATTCACCCGCCCTGATGCTA
AGGAAACCCTGACGTATGTACTAGATGGCAGGGCACTGGGGGTCAGGCTGAAGGCTGAGCAACACCTCTCTGCCCTCCCTCCCTTTGTCC
CATCTCCCAGCGACTTCCAATATTCATGTTTCTGAGAATTGTGTCCCTCTTCAGGTTCCCTCTTGGTGCCTAACCTGGATTAGTAATGTG
CATTCAGGTGAATTTTCAGCTGAGGCTCTGAGAACTGGTACTCTCAGTGTGTTCTGGTCATCTTGTGGCTTAGTTGTAGAAGCAGGTGTG
TCTCTTGCCTCTGCTTGCCTCCTACTGCACACTCAGCACCCAGGACTGGAATCACCGACTACTGAATCTCCTACATGTATTGCTGCTACT
TCAAGCTCCTCCACTTGAAACCTTATGATTTTCCCAAGGGGAGATGGGACAGTGTCATCTAAATATTCCGAATGTTTGGCCTTCTGAGAA
AAGAGCTTCTAGTAATTGAACCATGGGAAACCCAGCTTCTGGAGGGTTGGCCGTGGGGCTGTGTACATGTGTGTGCCCAGGGGTGAGTGT
TTCTCAGGATTCCTAACGATTCAAATTACCGTTGAGTATATATAAAGAATGAGTCTCTGTATGGAAGAACAAATGTGTGCATTCACCCCC
AGTCACAATGGTCTCCATTGCATTTCAAAGGAGAGGATCAGACTATCTGAATATAAACACAATCTGATGTTAATTTATTCTAAGAACACC
ATCATTTTGATTGTCCTAAAGAATTCTGCCTTTGTGAATACCGTGTTAAATTTTTTTAAATTTGTGACAGGATTGTAGCAAATTATTATT
TAAGGAAAATAAATTGTGTAAACATTTAATGTGGTATTTTTGAACAGCGGTTTTTATGTACTCAGAAGAGGAAGTAAAGCCAGGTTCTTA
ATGGTATTTATAGAAAAGATGTTTTCATATTATAATGCACATAAATGAAGCCATTTTGATATTCAGCAAATTCGGTGCCAATTGAATAGT
TTGCTGGTAGCAAGACGGATGAAGACCTATATGGGAGATTCTTTATCTCTAGAGCTAGCATATTTACTTGCATACTTTGTTTCTTTTCCA
CATGGATATTTTACTGCTAAATGGCAGAGGTGGGAGGGAGATGTCACACAGTACCATAACCCCATATTGAAAACAAGAAACCACCAGAAA
GTTTGCAGCTAAGGGGCAGGGGATTCAGTTCCTACGCCCACTCAGCACTAACTACTTGCGGGCCTGGTTGCTTAGAAGCTCTACCTCTCT
TTCATTATCTGTAAAATAGAAACAATACTTAGGACTTTAGTTGGAACATGAGGATTGAATAAGATCACGCTATTCATGTGACTTTTTATC
GGCTAGAACAGCAACAGACACTGCTGTGGGTGAGTTACTTAGAAAAGTTTAGTTATCAGTGATTAGCCCAAAAACACATCAGTCAAAAAT
AGAATCCACTGGATTTTTGTCTCTCTTTTTAGAGACAGGGTCTCACTGTCGCCCAGGCTGGAGTACAGTGGCATGATCATTGTTCACTGC
AGCCTCAAATTCCTGGGCTCAAGCAATCCTCGCACCTCAGCCTCCTGAGTAGCCGGGACTATAGGCACATGCCACCTCACCTGGCTTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAGAGACAGGATCTTGATGTGTTGCCTAGGCT
GGTCTCAAACTCCTGGCCTCAAGTGATCTTCCCACCTCAGCCTCCAAAACTGTTGGGATTATAGGCGTGAGCCACTGTGCCCAGCCTAAC
TGGGTTTTTATGAGAGGAAAATAGAAAATGCTCTTCTAGAAGAGAGAGAACAAGAGCACAAAATAATCTGGACTCACAAAAATTCAGCAA
GCTCCAAGAAAGGGGGATGGAGGGAACGCTGGCAAAAATTTAAATGCCATTAGGATATTTAGCAAGTTATTACTGTTTGGTAAAAATGCA
TCATCACCCTGTGTGCAAAATGCTTGCAAAGTAGTCTAAATGTCTTTGGAGATGGGTGTTTTACTGCTTTTTTCCAAAAACAAATTGTTT
ATTATGGTTGCAGAAATGCAGCCATTACGGTCACATAAATTTCTAAAAAGCCTACCAAAGGTTGCAAGCAGTCTTCTGCCACTGGGCAGG
CCAGCAGTTCAGACCCAGCGAGGTTGCCAGGAACAAATCCAGGAAATACTGGGAAGAACAAGACAAGAGAATTACCTAAAAGAGCAAACA
ATTCAAGTAAATCCTGTAGCTATTACCACTTAAAATCCGTAGCTCAAGATTCCTGTTTCACCACCTTATACACTTAAGCAATTATACTTA
AGCCTTTTTTTAGTCCTAAGTGAAGAACTACATCAGAATCAGGATAAGTATTTTGCCTGGGAAATTTGGCTGCATATGAATGGAGAAGAC
ATTTACATCCTATGTTCTGGCACTTTCTGAAAGATCTAATTAAACATGTTGATGTGCCAATTTAATCAAGATGAGAGATCCCTGCTGGTG
TCACCCTCTAGAACCTGCACTTGGTGTTTTGACTTTCCAGAAGAAAAAAATGCAACTTTGGTTAGGGGGCAGTGGTTGGATCACACAGTT
GTCTTTCGTTTCCTACCACAGTAATTCATATTTAAATATGCTTTTAGATTAGTGTGGATACTATTGCTGCTGTGTTGCTACCTGACCTTT
TTCTGGGGGGGGTACCTCAGAAATGAGCATTTGAGGGCAAGCGAAAAAGCCCTCTTCATCCTCCAGAGGCAACAAAGAGGCAGCAGAAAT
GGGGAAAGATTGTGAGAGGCAGGGCTTGGGTCTAGACCTGGACTTAGGCAAGATATGTTGCCCTCAACCCTGAGTTTTCTTATATGTAAA
AAGGGAAGGTTGGGCTGGACTAGATGAGGTCAAGATTTGCCATTCTGGGAGGCTGATATTCCAGAGAATCAAAATTAATCCTAAACCAAA
GCTTTATGGCTGCTACAGAGACATGTCACATTTCTGAGACTTGTCACCAAGAGTTTGTCCCTCAGACTTTGGCGCTGTTGAATGCAAAGA
CAAGGATGGCCACCTTCTGGTTCTTGCCTGTTGTCCTCAGCTGAGAGCAGTCTCGGTAAAGGTGGCAAAGATTCTGTGACCTCAGACCGG
GGACCAAATGCTTGGGAGTCTGATGGCCGGGCTGGGCCACCATTCTCATAGCTCTCATTCTGTTTGGAGCAACCAAAGGATTTGTGTGAA
GTTATTTGGAAAAGGACCTTAACTGAGCAGTAATCTTTTTTCTGTATATTTGGAATGTTTTTCATTCTGACCTGTTCTGTCAGTGATTCT

>39361_39361_9_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000537196_PTPN3_chr9_112153841_ENST00000412145_length(amino acids)=273AA_BP=6
MPVTRFLFINVQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQ
VVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSD
FLEFVNYVRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQML

--------------------------------------------------------------
>39361_39361_10_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000537196_PTPN3_chr9_112153841_ENST00000446349_length(transcript)=5361nt_BP=710nt
GGGTGCGGACTGTGGGAGCTGACTCTGGGTAGCCGGCTGCGCGTGGCTGGGGAGGCGAGGCCGGACGCACCTCTGTTTGGGGGTCCTCAG
ACCCTCAGGCAGTTTGATTGCATCTACACAAGATAAACCCAACCAGCAGGATATTGTGTTTTTTGAGAAAAATGGACTCCTTCATGGACA
CTTTACACTTCCCTTCCTTAAAGATGAGGTTAAGGTAAATGACTTGCTCTGGAATGCAGATTCCTCTGTGCTTGCAGTCTGGCTGGAAGA
CCTTCAGAGAGAAGAAAGCTCCATTCCGAAAACCTGTGTTCAGCTCTGGACTGTTGGAAACTATCACTGGTATCTCAAGCAAAGTTTATC
CTTCAGCACCTGTGGGAAGAGCAAGATTGTGTCTCTGATGTGGGACCCTGTGACCCCATACCGGCTGCATGTTCTCTGTCAGGGCTGGCA
TTACCTCGCCTATGATTGGCACTGGACGACTGACCGGAGCGTGGGAGATAATTCAAGTGACTTGTCCAATGTGGCTGTCATTGATGGAAA
CAGGGTGTTGGTGACAGTCTTCCGGCAGACTGTGGTTCCGCCTCCCATGTGCACCTACCAACTGCTGTTCCCACACCCTGTGAATCAAGT
CACATTCTTAGCACACCCTCAAAAGAGTAATGACCTTGCTGTTCTAGATGCCAGTAACCAGATTTCTGTTTATAAATGTGCAACTCTACA
GAAAAAAGCCAGGTTTGGCCATCACGTTTGCAAAGCTGCCTCAAAATTTGGACAAAAACCGATATAAAGATGTGCTGCCTTATGACACCA
CCCGGGTATTATTGCAGGGAAATGAAGATTATATTAATGCAAGTTACGTGAACATGGAAATTCCTGCTGCTAACCTTGTGAACAAGTACA
TCGCCACTCAGGGGCCCCTGCCGCATACCTGTGCACAGTTTTGGCAGGTTGTCTGGGATCAGAAGTTGTCACTCATTGTCATGTTGACGA
CTCTCACAGAACGAGGGCGGACCAAATGTCACCAGTACTGGCCAGATCCCCCCGACGTCATGAACCACGGCGGCTTTCACATCCAGTGTC
AGTCAGAGGACTGCACCATCGCCTATGTGTCCCGAGAAATGCTGGTCACAAACACCCAGACCGGGGAAGAACACACAGTGACACATCTCC
AGTACGTCGCATGGCCTGACCACGGTGTGCCCGATGACTCCTCCGACTTTCTGGAATTTGTAAACTATGTGAGGTCTCTGAGAGTGGACA
GCGAGCCCGTCCTAGTTCACTGCAGTGCTGGAATAGGTCGAACCGGTGTGTTGGTCACTATGGAAACAGCCATGTGCCTAACTGAGAGGA
ACCTGCCCATTTACCCACTGGATATTGTCCGAAAAATGCGAGACCAGCGCGCCATGATGGTGCAGACATCAAGCCAGTACAAGTTTGTGT
GTGAAGCGATTCTTCGTGTGTATGAAGAAGGTTTAGTCCAAATGCTGGATCCTAGTTAAGACAACTGTGAAAAAGTTCATTCCTCTTTCC
CAAGGGCATCCTCCTTGAAAGAGGAGGACAGACCTCTCTGGAAGCAGCAAGAGGAACCAGTAGCTGTGGGAAAGGAATGGGCACCTCTGA
ACCCAGGCACTTTAAACTTCTATAGAAAAGATATCGTGTACATAGGAACTGGTGTAGATAAGCATGCAATTATGGCATCATTTAGGCCTG
TATTTCTATGGAAAGATACAAAAAGGATCTCAGTTTGGGGCCTGTCCTAATGCCTTCTTCCCTAACATCACCACACACACCCCTGTCGGC
ATCCTGGAGCAATTGAGACCGGACACCCACAGAGCTGTTGTCCTCCCAGCAACAAGATGGTGTGGTTATCTTGGGTCATTTGGATGTTTT
GTTTGTTTCTGTGTGTCAGACTGTAAGGGCTGAGCTTTCTGTGCTTCTAGGTGGAGCTGGAACAATTCAGATTCACCCGCCCTGATGCTA
AGGAAACCCTGACGTATGTACTAGATGGCAGGGCACTGGGGGTCAGGCTGAAGGCTGAGCAACACCTCTCTGCCCTCCCTCCCTTTGTCC
CATCTCCCAGCGACTTCCAATATTCATGTTTCTGAGAATTGTGTCCCTCTTCAGGTTCCCTCTTGGTGCCTAACCTGGATTAGTAATGTG
CATTCAGGTGAATTTTCAGCTGAGGCTCTGAGAACTGGTACTCTCAGTGTGTTCTGGTCATCTTGTGGCTTAGTTGTAGAAGCAGGTGTG
TCTCTTGCCTCTGCTTGCCTCCTACTGCACACTCAGCACCCAGGACTGGAATCACCGACTACTGAATCTCCTACATGTATTGCTGCTACT
TCAAGCTCCTCCACTTGAAACCTTATGATTTTCCCAAGGGGAGATGGGACAGTGTCATCTAAATATTCCGAATGTTTGGCCTTCTGAGAA
AAGAGCTTCTAGTAATTGAACCATGGGAAACCCAGCTTCTGGAGGGTTGGCCGTGGGGCTGTGTACATGTGTGTGCCCAGGGGTGAGTGT
TTCTCAGGATTCCTAACGATTCAAATTACCGTTGAGTATATATAAAGAATGAGTCTCTGTATGGAAGAACAAATGTGTGCATTCACCCCC
AGTCACAATGGTCTCCATTGCATTTCAAAGGAGAGGATCAGACTATCTGAATATAAACACAATCTGATGTTAATTTATTCTAAGAACACC
ATCATTTTGATTGTCCTAAAGAATTCTGCCTTTGTGAATACCGTGTTAAATTTTTTTAAATTTGTGACAGGATTGTAGCAAATTATTATT
TAAGGAAAATAAATTGTGTAAACATTTAATGTGGTATTTTTGAACAGCGGTTTTTATGTACTCAGAAGAGGAAGTAAAGCCAGGTTCTTA
ATGGTATTTATAGAAAAGATGTTTTCATATTATAATGCACATAAATGAAGCCATTTTGATATTCAGCAAATTCGGTGCCAATTGAATAGT
TTGCTGGTAGCAAGACGGATGAAGACCTATATGGGAGATTCTTTATCTCTAGAGCTAGCATATTTACTTGCATACTTTGTTTCTTTTCCA
CATGGATATTTTACTGCTAAATGGCAGAGGTGGGAGGGAGATGTCACACAGTACCATAACCCCATATTGAAAACAAGAAACCACCAGAAA
GTTTGCAGCTAAGGGGCAGGGGATTCAGTTCCTACGCCCACTCAGCACTAACTACTTGCGGGCCTGGTTGCTTAGAAGCTCTACCTCTCT
TTCATTATCTGTAAAATAGAAACAATACTTAGGACTTTAGTTGGAACATGAGGATTGAATAAGATCACGCTATTCATGTGACTTTTTATC
GGCTAGAACAGCAACAGACACTGCTGTGGGTGAGTTACTTAGAAAAGTTTAGTTATCAGTGATTAGCCCAAAAACACATCAGTCAAAAAT
AGAATCCACTGGATTTTTGTCTCTCTTTTTAGAGACAGGGTCTCACTGTCGCCCAGGCTGGAGTACAGTGGCATGATCATTGTTCACTGC
AGCCTCAAATTCCTGGGCTCAAGCAATCCTCGCACCTCAGCCTCCTGAGTAGCCGGGACTATAGGCACATGCCACCTCACCTGGCTTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAGAGACAGGATCTTGATGTGTTGCCTAGGCT
GGTCTCAAACTCCTGGCCTCAAGTGATCTTCCCACCTCAGCCTCCAAAACTGTTGGGATTATAGGCGTGAGCCACTGTGCCCAGCCTAAC
TGGGTTTTTATGAGAGGAAAATAGAAAATGCTCTTCTAGAAGAGAGAGAACAAGAGCACAAAATAATCTGGACTCACAAAAATTCAGCAA
GCTCCAAGAAAGGGGGATGGAGGGAACGCTGGCAAAAATTTAAATGCCATTAGGATATTTAGCAAGTTATTACTGTTTGGTAAAAATGCA
TCATCACCCTGTGTGCAAAATGCTTGCAAAGTAGTCTAAATGTCTTTGGAGATGGGTGTTTTACTGCTTTTTTCCAAAAACAAATTGTTT
ATTATGGTTGCAGAAATGCAGCCATTACGGTCACATAAATTTCTAAAAAGCCTACCAAAGGTTGCAAGCAGTCTTCTGCCACTGGGCAGG
CCAGCAGTTCAGACCCAGCGAGGTTGCCAGGAACAAATCCAGGAAATACTGGGAAGAACAAGACAAGAGAATTACCTAAAAGAGCAAACA
ATTCAAGTAAATCCTGTAGCTATTACCACTTAAAATCCGTAGCTCAAGATTCCTGTTTCACCACCTTATACACTTAAGCAATTATACTTA
AGCCTTTTTTTAGTCCTAAGTGAAGAACTACATCAGAATCAGGATAAGTATTTTGCCTGGGAAATTTGGCTGCATATGAATGGAGAAGAC
ATTTACATCCTATGTTCTGGCACTTTCTGAAAGATCTAATTAAACATGTTGATGTGCCAATTTAATCAAGATGAGAGATCCCTGCTGGTG
TCACCCTCTAGAACCTGCACTTGGTGTTTTGACTTTCCAGAAGAAAAAAATGCAACTTTGGTTAGGGGGCAGTGGTTGGATCACACAGTT
GTCTTTCGTTTCCTACCACAGTAATTCATATTTAAATATGCTTTTAGATTAGTGTGGATACTATTGCTGCTGTGTTGCTACCTGACCTTT
TTCTGGGGGGGGTACCTCAGAAATGAGCATTTGAGGGCAAGCGAAAAAGCCCTCTTCATCCTCCAGAGGCAACAAAGAGGCAGCAGAAAT
GGGGAAAGATTGTGAGAGGCAGGGCTTGGGTCTAGACCTGGACTTAGGCAAGATATGTTGCCCTCAACCCTGAGTTTTCTTATATGTAAA
AAGGGAAGGTTGGGCTGGACTAGATGAGGTCAAGATTTGCCATTCTGGGAGGCTGATATTCCAGAGAATCAAAATTAATCCTAAACCAAA
GCTTTATGGCTGCTACAGAGACATGTCACATTTCTGAGACTTGTCACCAAGAGTTTGTCCCTCAGACTTTGGCGCTGTTGAATGCAAAGA
CAAGGATGGCCACCTTCTGGTTCTTGCCTGTTGTCCTCAGCTGAGAGCAGTCTCGGTAAAGGTGGCAAAGATTCTGTGACCTCAGACCGG
GGACCAAATGCTTGGGAGTCTGATGGCCGGGCTGGGCCACCATTCTCATAGCTCTCATTCTGTTTGGAGCAACCAAAGGATTTGTGTGAA
GTTATTTGGAAAAGGACCTTAACTGAGCAGTAATCTTTTTTCTGTATATTTGGAATGTTTTTCATTCTGACCTGTTCTGTCAGTGATTCT

>39361_39361_10_IKBKAP-PTPN3_IKBKAP_chr9_111673289_ENST00000537196_PTPN3_chr9_112153841_ENST00000446349_length(amino acids)=273AA_BP=6
MPVTRFLFINVQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQ
VVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSD
FLEFVNYVRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQML

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for IKBKAP-PTPN3

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for IKBKAP-PTPN3

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for IKBKAP-PTPN3

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source