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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:IL4R-RBBP6 (FusionGDB2 ID:39565)

Fusion Gene Summary for IL4R-RBBP6

check button Fusion gene summary
Fusion gene informationFusion gene name: IL4R-RBBP6
Fusion gene ID: 39565
HgeneTgene
Gene symbol

IL4R

RBBP6

Gene ID

3566

5930

Gene nameinterleukin 4 receptorRB binding protein 6, ubiquitin ligase
SynonymsCD124|IL-4RA|IL4RAMY038|P2P-R|PACT|RBQ-1|SNAMA
Cytomap

16p12.1

16p12.1

Type of geneprotein-codingprotein-coding
Descriptioninterleukin-4 receptor subunit alphaIL-4 receptor subunit alphaIL4R nirs variant 1interleukin 13 receptorinterleukin-4 receptor alpha chainE3 ubiquitin-protein ligase RBBP6RB-binding Q-protein 1RING-type E3 ubiquitin transferase RBBP6p53-associated cellular protein of testisproliferation potential-related proteinprotein P2P-Rretinoblastoma binding protein 6retinoblastoma-binding Q pro
Modification date2020032220200313
UniProtAcc

P24394

.
Ensembl transtripts involved in fusion geneENST00000380922, ENST00000170630, 
ENST00000395762, ENST00000449195, 
ENST00000543915, ENST00000565915, 
ENST00000319715, ENST00000348022, 
ENST00000381039, ENST00000452655, 
Fusion gene scores* DoF score9 X 8 X 5=3606 X 6 X 5=180
# samples 106
** MAII scorelog2(10/360*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/180*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: IL4R [Title/Abstract] AND RBBP6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointIL4R(27351594)-RBBP6(24557483), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneRBBP6

GO:0006511

ubiquitin-dependent protein catabolic process

18851979


check buttonFusion gene breakpoints across IL4R (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RBBP6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CN-A6V1IL4Rchr16

27351594

+RBBP6chr16

24557483

+


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Fusion Gene ORF analysis for IL4R-RBBP6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000380922ENST00000319715IL4Rchr16

27351594

+RBBP6chr16

24557483

+
5UTR-3CDSENST00000380922ENST00000348022IL4Rchr16

27351594

+RBBP6chr16

24557483

+
5UTR-3CDSENST00000380922ENST00000381039IL4Rchr16

27351594

+RBBP6chr16

24557483

+
5UTR-3CDSENST00000380922ENST00000452655IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000170630ENST00000319715IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000170630ENST00000348022IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000170630ENST00000381039IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000170630ENST00000452655IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000395762ENST00000319715IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000395762ENST00000348022IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000395762ENST00000381039IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000395762ENST00000452655IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000449195ENST00000319715IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000449195ENST00000348022IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000449195ENST00000381039IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000449195ENST00000452655IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000543915ENST00000319715IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000543915ENST00000348022IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000543915ENST00000381039IL4Rchr16

27351594

+RBBP6chr16

24557483

+
In-frameENST00000543915ENST00000452655IL4Rchr16

27351594

+RBBP6chr16

24557483

+
intron-3CDSENST00000565915ENST00000319715IL4Rchr16

27351594

+RBBP6chr16

24557483

+
intron-3CDSENST00000565915ENST00000348022IL4Rchr16

27351594

+RBBP6chr16

24557483

+
intron-3CDSENST00000565915ENST00000381039IL4Rchr16

27351594

+RBBP6chr16

24557483

+
intron-3CDSENST00000565915ENST00000452655IL4Rchr16

27351594

+RBBP6chr16

24557483

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000395762IL4Rchr1627351594+ENST00000319715RBBP6chr1624557483+596032923855411767
ENST00000395762IL4Rchr1627351594+ENST00000452655RBBP6chr1624557483+88632923851993
ENST00000395762IL4Rchr1627351594+ENST00000381039RBBP6chr1624557483+34403292383021927
ENST00000395762IL4Rchr1627351594+ENST00000348022RBBP6chr1624557483+585832923854391733
ENST00000543915IL4Rchr1627351594+ENST00000319715RBBP6chr1624557483+581418311353951760
ENST00000543915IL4Rchr1627351594+ENST00000452655RBBP6chr1624557483+740183270190
ENST00000543915IL4Rchr1627351594+ENST00000381039RBBP6chr1624557483+32941831132875920
ENST00000543915IL4Rchr1627351594+ENST00000348022RBBP6chr1624557483+571218311352931726
ENST00000449195IL4Rchr1627351594+ENST00000319715RBBP6chr1624557483+594331222155241767
ENST00000449195IL4Rchr1627351594+ENST00000452655RBBP6chr1624557483+86931222150293
ENST00000449195IL4Rchr1627351594+ENST00000381039RBBP6chr1624557483+34233122213004927
ENST00000449195IL4Rchr1627351594+ENST00000348022RBBP6chr1624557483+584131222154221733
ENST00000170630IL4Rchr1627351594+ENST00000319715RBBP6chr1624557483+5722912153031760
ENST00000170630IL4Rchr1627351594+ENST00000452655RBBP6chr1624557483+648912128186
ENST00000170630IL4Rchr1627351594+ENST00000381039RBBP6chr1624557483+320291212783920
ENST00000170630IL4Rchr1627351594+ENST00000348022RBBP6chr1624557483+5620912152011726

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000395762ENST00000319715IL4Rchr1627351594+RBBP6chr1624557483+0.0004058380.99959415
ENST00000395762ENST00000452655IL4Rchr1627351594+RBBP6chr1624557483+0.303682450.69631755
ENST00000395762ENST00000381039IL4Rchr1627351594+RBBP6chr1624557483+0.0003572220.9996427
ENST00000395762ENST00000348022IL4Rchr1627351594+RBBP6chr1624557483+0.000405930.99959403
ENST00000543915ENST00000319715IL4Rchr1627351594+RBBP6chr1624557483+0.0003507430.9996493
ENST00000543915ENST00000452655IL4Rchr1627351594+RBBP6chr1624557483+0.224228130.7757719
ENST00000543915ENST00000381039IL4Rchr1627351594+RBBP6chr1624557483+0.0003656680.99963427
ENST00000543915ENST00000348022IL4Rchr1627351594+RBBP6chr1624557483+0.0003493560.9996506
ENST00000449195ENST00000319715IL4Rchr1627351594+RBBP6chr1624557483+0.0003988720.9996012
ENST00000449195ENST00000452655IL4Rchr1627351594+RBBP6chr1624557483+0.469979140.5300209
ENST00000449195ENST00000381039IL4Rchr1627351594+RBBP6chr1624557483+0.0003577930.99964225
ENST00000449195ENST00000348022IL4Rchr1627351594+RBBP6chr1624557483+0.0003990510.99960095
ENST00000170630ENST00000319715IL4Rchr1627351594+RBBP6chr1624557483+0.0003334850.9996666
ENST00000170630ENST00000452655IL4Rchr1627351594+RBBP6chr1624557483+0.267261270.7327387
ENST00000170630ENST00000381039IL4Rchr1627351594+RBBP6chr1624557483+0.0004024890.9995975
ENST00000170630ENST00000348022IL4Rchr1627351594+RBBP6chr1624557483+0.000326740.99967325

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Fusion Genomic Features for IL4R-RBBP6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
IL4Rchr1627351594+RBBP6chr1624557483+0.0010016120.99899834
IL4Rchr1627351594+RBBP6chr1624557483+0.0010016120.99899834

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for IL4R-RBBP6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:27351594/chr16:24557483)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
IL4R

P24394

.
FUNCTION: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. {ECO:0000269|PubMed:8124718}.; FUNCTION: Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells. {ECO:0000269|PubMed:8124718}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRBBP6chr16:27351594chr16:24557483ENST00000319715018560_565551793.0MotifPPxPxY
TgeneRBBP6chr16:27351594chr16:24557483ENST00000348022017560_565551759.0MotifPPxPxY
TgeneRBBP6chr16:27351594chr16:24557483ENST00000381039011560_56555953.0MotifPPxPxY
TgeneRBBP6chr16:27351594chr16:24557483ENST0000045265503560_56555119.0MotifPPxPxY
TgeneRBBP6chr16:27351594chr16:24557483ENST00000319715018159_176551793.0Zinc fingerCCHC-type
TgeneRBBP6chr16:27351594chr16:24557483ENST00000319715018259_300551793.0Zinc fingerRING-type%3B degenerate
TgeneRBBP6chr16:27351594chr16:24557483ENST00000348022017159_176551759.0Zinc fingerCCHC-type
TgeneRBBP6chr16:27351594chr16:24557483ENST00000348022017259_300551759.0Zinc fingerRING-type%3B degenerate
TgeneRBBP6chr16:27351594chr16:24557483ENST00000381039011159_17655953.0Zinc fingerCCHC-type
TgeneRBBP6chr16:27351594chr16:24557483ENST00000381039011259_30055953.0Zinc fingerRING-type%3B degenerate
TgeneRBBP6chr16:27351594chr16:24557483ENST0000045265503159_17655119.0Zinc fingerCCHC-type
TgeneRBBP6chr16:27351594chr16:24557483ENST0000045265503259_30055119.0Zinc fingerRING-type%3B degenerate

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIL4Rchr16:27351594chr16:24557483ENST00000170630+19370_38023826.0Compositional biasNote=Poly-Glu
HgeneIL4Rchr16:27351594chr16:24557483ENST00000170630+19563_56623826.0Compositional biasNote=Poly-Ala
HgeneIL4Rchr16:27351594chr16:24557483ENST00000170630+19789_79423826.0Compositional biasNote=Poly-Ser
HgeneIL4Rchr16:27351594chr16:24557483ENST00000395762+311370_38023826.0Compositional biasNote=Poly-Glu
HgeneIL4Rchr16:27351594chr16:24557483ENST00000395762+311563_56623826.0Compositional biasNote=Poly-Ala
HgeneIL4Rchr16:27351594chr16:24557483ENST00000395762+311789_79423826.0Compositional biasNote=Poly-Ser
HgeneIL4Rchr16:27351594chr16:24557483ENST00000449195+38370_38023228.0Compositional biasNote=Poly-Glu
HgeneIL4Rchr16:27351594chr16:24557483ENST00000449195+38563_56623228.0Compositional biasNote=Poly-Ala
HgeneIL4Rchr16:27351594chr16:24557483ENST00000449195+38789_79423228.0Compositional biasNote=Poly-Ser
HgeneIL4Rchr16:27351594chr16:24557483ENST00000543915+210370_38023826.0Compositional biasNote=Poly-Glu
HgeneIL4Rchr16:27351594chr16:24557483ENST00000543915+210563_56623826.0Compositional biasNote=Poly-Ala
HgeneIL4Rchr16:27351594chr16:24557483ENST00000543915+210789_79423826.0Compositional biasNote=Poly-Ser
HgeneIL4Rchr16:27351594chr16:24557483ENST00000170630+19125_22423826.0DomainFibronectin type-III
HgeneIL4Rchr16:27351594chr16:24557483ENST00000395762+311125_22423826.0DomainFibronectin type-III
HgeneIL4Rchr16:27351594chr16:24557483ENST00000449195+38125_22423228.0DomainFibronectin type-III
HgeneIL4Rchr16:27351594chr16:24557483ENST00000543915+210125_22423826.0DomainFibronectin type-III
HgeneIL4Rchr16:27351594chr16:24557483ENST00000170630+19212_21623826.0MotifNote=WSXWS motif
HgeneIL4Rchr16:27351594chr16:24557483ENST00000170630+19262_27023826.0MotifNote=Box 1 motif
HgeneIL4Rchr16:27351594chr16:24557483ENST00000170630+19711_71623826.0MotifNote=ITIM motif
HgeneIL4Rchr16:27351594chr16:24557483ENST00000395762+311212_21623826.0MotifNote=WSXWS motif
HgeneIL4Rchr16:27351594chr16:24557483ENST00000395762+311262_27023826.0MotifNote=Box 1 motif
HgeneIL4Rchr16:27351594chr16:24557483ENST00000395762+311711_71623826.0MotifNote=ITIM motif
HgeneIL4Rchr16:27351594chr16:24557483ENST00000449195+38212_21623228.0MotifNote=WSXWS motif
HgeneIL4Rchr16:27351594chr16:24557483ENST00000449195+38262_27023228.0MotifNote=Box 1 motif
HgeneIL4Rchr16:27351594chr16:24557483ENST00000449195+38711_71623228.0MotifNote=ITIM motif
HgeneIL4Rchr16:27351594chr16:24557483ENST00000543915+210212_21623826.0MotifNote=WSXWS motif
HgeneIL4Rchr16:27351594chr16:24557483ENST00000543915+210262_27023826.0MotifNote=Box 1 motif
HgeneIL4Rchr16:27351594chr16:24557483ENST00000543915+210711_71623826.0MotifNote=ITIM motif
HgeneIL4Rchr16:27351594chr16:24557483ENST00000170630+19437_55723826.0RegionNote=Required for IRS1 activation and IL4-induced cell growth
HgeneIL4Rchr16:27351594chr16:24557483ENST00000170630+19558_65723826.0RegionNote=Required for IL4-induced gene expression
HgeneIL4Rchr16:27351594chr16:24557483ENST00000395762+311437_55723826.0RegionNote=Required for IRS1 activation and IL4-induced cell growth
HgeneIL4Rchr16:27351594chr16:24557483ENST00000395762+311558_65723826.0RegionNote=Required for IL4-induced gene expression
HgeneIL4Rchr16:27351594chr16:24557483ENST00000449195+38437_55723228.0RegionNote=Required for IRS1 activation and IL4-induced cell growth
HgeneIL4Rchr16:27351594chr16:24557483ENST00000449195+38558_65723228.0RegionNote=Required for IL4-induced gene expression
HgeneIL4Rchr16:27351594chr16:24557483ENST00000543915+210437_55723826.0RegionNote=Required for IRS1 activation and IL4-induced cell growth
HgeneIL4Rchr16:27351594chr16:24557483ENST00000543915+210558_65723826.0RegionNote=Required for IL4-induced gene expression
HgeneIL4Rchr16:27351594chr16:24557483ENST00000170630+19257_82523826.0Topological domainCytoplasmic
HgeneIL4Rchr16:27351594chr16:24557483ENST00000170630+1926_23223826.0Topological domainExtracellular
HgeneIL4Rchr16:27351594chr16:24557483ENST00000395762+311257_82523826.0Topological domainCytoplasmic
HgeneIL4Rchr16:27351594chr16:24557483ENST00000395762+31126_23223826.0Topological domainExtracellular
HgeneIL4Rchr16:27351594chr16:24557483ENST00000449195+38257_82523228.0Topological domainCytoplasmic
HgeneIL4Rchr16:27351594chr16:24557483ENST00000449195+3826_23223228.0Topological domainExtracellular
HgeneIL4Rchr16:27351594chr16:24557483ENST00000543915+210257_82523826.0Topological domainCytoplasmic
HgeneIL4Rchr16:27351594chr16:24557483ENST00000543915+21026_23223826.0Topological domainExtracellular
HgeneIL4Rchr16:27351594chr16:24557483ENST00000170630+19233_25623826.0TransmembraneHelical
HgeneIL4Rchr16:27351594chr16:24557483ENST00000395762+311233_25623826.0TransmembraneHelical
HgeneIL4Rchr16:27351594chr16:24557483ENST00000449195+38233_25623228.0TransmembraneHelical
HgeneIL4Rchr16:27351594chr16:24557483ENST00000543915+210233_25623826.0TransmembraneHelical
TgeneRBBP6chr16:27351594chr16:24557483ENST000003197150184_76551793.0DomainDWNN
TgeneRBBP6chr16:27351594chr16:24557483ENST000003480220174_76551759.0DomainDWNN
TgeneRBBP6chr16:27351594chr16:24557483ENST000003810390114_7655953.0DomainDWNN
TgeneRBBP6chr16:27351594chr16:24557483ENST00000452655034_7655119.0DomainDWNN


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Fusion Gene Sequence for IL4R-RBBP6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>39565_39565_1_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000170630_RBBP6_chr16_24557483_ENST00000319715_length(transcript)=5722nt_BP=91nt
CAGGTGCCTTGGCATCTCCCAATGGGGTGGCTTTGCTCTGGGCTCCTGTTCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCTCT
GAATATACTGATGATAATGCTCTGATTCCTAAGAATTCTTCTGTAATTGTTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCAAG
ACATATGTTATAAGTCGAACTGAACCAGCGATGGCAACTACAAAAGCAATTGATGACTCTTCCGCGTCTATTTCTCTGGCCCAGCTTACA
AAGACTGCCAATCTGGCTGAAGCCAATGCTTCTGAAGAAGATAAAATTAAAGCAATGATGTCGCAATCTGGCCATGAATACGACCCAATC
AATTACATGAAGAAACCTCTAGGTCCACCACCTCCATCTTACACGTGTTTCCGTTGTGGTAAACCTGGACATTATATTAAGAATTGCCCA
ACAAATGGGGATAAAAACTTTGAATCTGGTCCTAGGATTAAAAAGAGCACTGGAATTCCCAGAAGTTTCATGATGGAAGTGAAAGATCCT
AATATGAAAGGTGCAATGCTTACCAACACTGGAAAATATGCAATACCAACTATAGATGCAGAAGCATATGCAATTGGGAAGAAAGAGAAA
CCTCCCTTCTTACCAGAGGAGCCATCTTCTTCCTCAGAAGAAGATGATCCTATCCCAGATGAATTGTTGTGTCTCATCTGCAAGGATATT
ATGACTGATGCTGTTGTGATTCCCTGCTGTGGAAACAGTTACTGTGATGAATGTATAAGAACAGCACTCCTGGAATCAGATGAGCACACA
TGTCCGACGTGTCATCAAAATGATGTTTCTCCTGATGCTTTAATTGCCAATAAATTTTTACGACAGGCTGTAAATAACTTCAAAAATGAA
ACTGGCTATACAAAAAGACTACGAAAACAGTTACCTCCTCCACCACCCCCAATACCACCTCCGAGACCACTGATTCAGAGGAACCTACAA
CCTCTGATGAGATCTCCGATATCAAGACAACAAGATCCTCTTATGATTCCAGTGACATCTTCATCAACTCACCCAGCTCCGTCTATATCT
TCATTAACTTCTAATCAGTCTTCCTTGGCCCCTCCTGTGTCTGGAAATCCGTCTTCTGCTCCAGCTCCTGTACCTGATATAACTGCAACA
GTATCCATATCAGTTCATTCAGAAAAATCAGATGGACCTTTTCGGGATTCTGATAATAAAATATTGCCAGCTGCAGCTCTTGCATCAGAG
CACTCAAAGGGAACCTCCTCAATTGCAATTACCGCTCTTATGGAAGAGAAGGGTTACCAGGTGCCTGTTCTTGGAACCCCATCTTTGCTT
GGACAGTCATTATTGCATGGACAGTTGATCCCCACAACTGGTCCAGTAAGAATAAATACTGCTCGTCCAGGTGGTGGTCGACCAGGCTGG
GAACATTCCAACAAACTTGGCTATCTGGTTTCTCCACCACAACAAATTAGAAGAGGGGAGAGGAGCTGCTACAGAAGTATAAACCGTGGG
CGACACCACAGCGAAAGATCACAGAGGACTCAAGGCCCGTCACTACCAGCAACTCCAGTCTTTGTACCTGTTCCACCACCTCCTTTGTAT
CCGCCTCCTCCCCATACACTTCCTCTCCCTCCGGGTGTTCCTCCTCCACAGTTTTCTCCTCAGTTTCCTCCTGGCCAGCCACCACCCGCT
GGGTATAGTGTCCCTCCTCCAGGGTTTCCTCCAGCTCCTGCCAATTTATCAACACCTTGGGTATCATCAGGAGTGCAGACAGCTCATTCA
AATACCATCCCAACAACACAAGCACCACCTTTGTCCAGGGAAGAATTCTATAGAGAGCAGCGACGACTAAAAGAAGAGGAAAAGAAAAAG
TCCAAGCTAGATGAGTTTACAAATGATTTTGCTAAGGAATTGATGGAATACAAAAAGATTCAAAAGGAGCGTAGGCGCTCATTTTCCAGG
TCTAAATCTCCCTATAGTGGTTCTTCGTATTCAAGAAGTTCATATACTTATTCTAAATCAAGATCTGGTTCAACACGTTCACGCTCTTAT
TCTCGATCATTCAGCCGCTCACATTCTCGTTCCTATTCACGGTCACCTCCATACCCCAGAAGAGGCAGAGGCAAGAGCCGCAATTACCGT
TCACGGTCTAGATCTCATGGATATCATCGATCTAGGTCAAGGTCACCCCCTTACAGACGCTATCATTCACGATCAAGATCTCCTCAAGCG
TTTAGGGGACAGTCTCCTAATAAACGTAATGTACCTCAAGGGGAAACAGAACGTGAATATTTTAATAGATACAGAGAAGTTCCACCACCA
TATGACATGAAAGCATATTATGGGAGAAGTGTTGACTTTAGAGACCCATTTGAAAAAGAACGCTACCGAGAATGGGAGAGAAAATATAGA
GAGTGGTATGAAAAATATTATAAAGGTTATGCTGCTGGAGCACAGCCTAGACCCTCAGCAAATAGAGAGAACTTTTCTCCAGAGAGATTT
TTGCCACTTAACATCAGGAATTCTCCCTTCACAAGAGGCCGCAGAGAAGACTATGTTGGTGGGCAAAGTCATAGAAGTCGAAACATAGGT
AGCAACTATCCAGAAAAGCTTTCAGCAAGAGATGGTCACAATCAGAAGGATAATACAAAGTCAAAAGAGAAGGAGAGTGAAAACGCTCCA
GGAGATGGTAAAGGAAATAAGCATAAGAAACACAGAAAAAGAAGAAAAGGGGAGGAAAGTGAGGGTTTTCTGAACCCAGAGTTATTAGAG
ACTTCTAGGAAATCAAGAGAACCTACAGGTGTTGAAGAAAATAAAACAGACTCATTGTTTGTTCTCCCAAGTAGAGATGATGCCACACCT
GTTAGAGATGAACCAATGGATGCAGAATCAATCACTTTTAAATCAGTGTCTGAAAAAGACAAGAGAGAAAGGGATAAACCAAAAGCAAAG
GGTGATAAAACCAAACGGAAGAATGATGGATCTGCTGTGTCCAAAAAAGAAAATATTGTAAAACCTGCTAAAGGACCCCAAGAAAAAGTA
GATGGAGAACGTGAGAGATCTCCTCGATCTGAACCTCCAATTAAAAAAGCCAAAGAGGAGACTCCGAAGACTGACAATACTAAATCATCA
TCTTCCTCTCAGAAGGATGAAAAAATCACTGGAACCCCCAGAAAAGCTCACTCTAAATCAGCAAAAGAACACCAAGAAACAAAACCAGTC
AAAGAGGAAAAAGTGAAGAAGGACTATTCCAAAGATGTCAAATCAGAAAAGCTAACAACTAAGGAAGAAAAGGCCAAGAAGCCTAATGAG
AAAAACAAACCACTTGATAATAAGGGAGAAAAAAGAAAAAGAAAAACTGAAGAAAAAGGCGTAGATAAAGATTTTGAGTCTTCTTCAATG
AAAATCTCGAAACTAGAAGTGACTGAAATAGTGAAACCATCACCAAAGCGCAAAATGGAACCTGATACTGAAAAAATGGATAGGACCCCT
GAAAAGGACAAAATTTCTTTAAGTGCGCCAGCCAAAAAAATCAAACTCAACAGAGAAACTGGGAAGAAAATTGGAAGTACAGAAAATATA
TCAAACACAAAAGAACCCTCTGAAAAATTGGAGTCAACATCTAGCAAAGTTAAACAAGAAAAAGTCAAAGGAAAGGTCAGACGAAAAGTG
ACTGGAACTGAAGGATCCAGCTCAACTCTGGTGGATTACACCAGTACGAGCTCAACTGGAGGCAGTCCTGTGCGGAAATCTGAAGAAAAA
ACAGATACAAAGCGAACTGTGATTAAAACGATGGAAGAATATAATAATGACAATACCGCGCCAGCTGAAGATGTTATCATTATGATTCAG
GTTCCTCAATCCAAATGGGATAAAGATGACTTTGAATCTGAAGAAGAAGATGTTAAATCCACACAGCCTATATCAAGTGTAGGAAAACCT
GCTAGTGTTATAAAAAATGTTAGTACAAAGCCATCAAATATAGTCAAGTATCCTGAGAAAGAAAGTGAGCCATCCGAGAAAATTCAGAAA
TTCACCAAGGACGTGAGCCATGAAATCATACAACATGAGGTTAAAAGTTCAAAAAACTCTGCATCTAGTGAAAAAGGGAAAACCAAAGAT
CGAGATTATTCAGTGTTGGAAAAGGAGAACCCTGAAAAGAGGAAGAACAGCACTCAGCCAGAGAAAGAGAGTAATTTGGACCGTCTGAAT
GAACAAGGAAATTTTAAAAGTCTGTCTCAATCTTCCAAAGAGGCTAGAACGTCAGATAAACATGATTCCACTCGTGCTTCCTCAAATAAA
GACTTCACTCCCAATAGAGACAAAAAAACTGACTATGACACCAGAGAGTATTCAAGTTCCAAACGTAGAGATGAAAAGAATGAATTAACA
AGACGAAAAGACTCTCCTTCTCGGAATAAAGATTCTGCATCTGGACAGAAAAATAAACCAAGGGAAGAGAGAGATTTGCCTAAAAAAGGA
ACAGGAGATTCCAAAAAAAGTAATTCTAGTCCCTCAAGAGACAGAAAACCTCATGATCACAAAGCCACTTATGATACTAAACGGCCAAAT
GAAGAGACAAAATCTGTAGATAAAAATCCTTGTAAGGATCGTGAGAAGCATGTATTAGAAGCAAGGAACAATAAAGAGTCAAGTGGCAAT
AAACTACTTTATATACTTAACCCACCAGAGACACAGGTTGAAAAAGAGCAAATTACTGGGCAAATTGACAAGAGTACTGTCAAGCCTAAA
CCCCAGTTAAGTCATTCCTCTAGACTTTCCTCTGACTTAACTAGAGAAACTGATGAAGCTGCTTTTGAACCAGACTATAATGAAAGTGAC
AGTGAAAGTAATGTTTCTGTAAAAGAAGAGGAATCTTCAGGAAACATTTCTAAGGACCTGAAAGATAAAATAGTGGAGAAAGCAAAAGAG
AGCCTGGACACAGCAGCAGTTGTCCAGGTGGGCATAAGCAGGAATCAGAGCCACAGCAGCCCCAGCGTCAGCCCCAGCAGAAGCCACAGT
CCTTCTGGAAGCCAGACCCGAAGCCACAGTAGCAGTGCCAGCTCAGCAGAAAGTCAGGACAGCAAGAAGAAGAAGAAAAAGAAGGAAAAG
AAAAAACACAAGAAACATAAAAAGCATAAGAAGCATAAGAAACATGCAGGCACTGAAGTGGAATTGGAAAAAAGCCAAAAACACAAACAC
AAGAAAAAGAAGTCAAAGAAGAACAAAGATAAAGAGAAGGAGAAGGAGAAAGATGACCAAAAAGTGAAATCTGTCACTGTGTAAAAAGAC
AGATTTTTTAAATTGACTTAATTACTAAGTCATCTGTATTAAATTTTGTTATAATGTAAAGAGATTCAAGCCTTGTAAATAATGACATGG
AAGACCCTGTGCTGCACTTAAAATATTGCTGCTTGATTATTTGATTTTTACATCAGAGCTTTATAACACGAACTTTTGTACAGAATTGTG
AGTTGTGACCATGTAACATGAGAGGTTTTGCTAGGGCCTATTATTTTTAACCACCATTAATTAGTTGGGGTGGAGTTTACTGTAATGTGA
AATTTTCACATTTGAATTTTTTAATTGCCTGGCAAAAGCTGATATAAGTTCTAAAATATCAGCAGAATGATTTGCTGAATTCATTACAAC

>39565_39565_1_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000170630_RBBP6_chr16_24557483_ENST00000319715_length(amino acids)=1760AA_BP=1691
MGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANLAE
ANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGAML
TNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCHQN
DVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQS
SLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLLHG
QLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTL
PLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKKSKLDEFT
NDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHG
YHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYY
KGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNK
HKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRK
NDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKK
DYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISL
SAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTV
IKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSH
EIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRD
KKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVD
KNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSV
KEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHK

--------------------------------------------------------------
>39565_39565_2_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000170630_RBBP6_chr16_24557483_ENST00000348022_length(transcript)=5620nt_BP=91nt
CAGGTGCCTTGGCATCTCCCAATGGGGTGGCTTTGCTCTGGGCTCCTGTTCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCTCT
GAATATACTGATGATAATGCTCTGATTCCTAAGAATTCTTCTGTAATTGTTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCAAG
ACATATGTTATAAGTCGAACTGAACCAGCGATGGCAACTACAAAAGCAATTGATGACTCTTCCGCGTCTATTTCTCTGGCCCAGCTTACA
AAGACTGCCAATCTGGCTGAAGCCAATGCTTCTGAAGAAGATAAAATTAAAGCAATGATGTCGCAATCTGGCCATGAATACGACCCAATC
AATTACATGAAGAAACCTCTAGGTCCACCACCTCCATCTTACACGTGTTTCCGTTGTGGTAAACCTGGACATTATATTAAGAATTGCCCA
ACAAATGGGGATAAAAACTTTGAATCTGGTCCTAGGATTAAAAAGAGCACTGGAATTCCCAGAAGTTTCATGATGGAAGTGAAAGATCCT
AATATGAAAGGTGCAATGCTTACCAACACTGGAAAATATGCAATACCAACTATAGATGCAGAAGCATATGCAATTGGGAAGAAAGAGAAA
CCTCCCTTCTTACCAGAGGAGCCATCTTCTTCCTCAGAAGAAGATGATCCTATCCCAGATGAATTGTTGTGTCTCATCTGCAAGGATATT
ATGACTGATGCTGTTGTGATTCCCTGCTGTGGAAACAGTTACTGTGATGAATGTATAAGAACAGCACTCCTGGAATCAGATGAGCACACA
TGTCCGACGTGTCATCAAAATGATGTTTCTCCTGATGCTTTAATTGCCAATAAATTTTTACGACAGGCTGTAAATAACTTCAAAAATGAA
ACTGGCTATACAAAAAGACTACGAAAACAGTTACCTCCTCCACCACCCCCAATACCACCTCCGAGACCACTGATTCAGAGGAACCTACAA
CCTCTGATGAGATCTCCGATATCAAGACAACAAGATCCTCTTATGATTCCAGTGACATCTTCATCAACTCACCCAGCTCCGTCTATATCT
TCATTAACTTCTAATCAGTCTTCCTTGGCCCCTCCTGTGTCTGGAAATCCGTCTTCTGCTCCAGCTCCTGTACCTGATATAACTGCAACA
GTATCCATATCAGTTCATTCAGAAAAATCAGATGGACCTTTTCGGGATTCTGATAATAAAATATTGCCAGCTGCAGCTCTTGCATCAGAG
CACTCAAAGGGAACCTCCTCAATTGCAATTACCGCTCTTATGGAAGAGAAGGGTTACCAGGTGCCTGTTCTTGGAACCCCATCTTTGCTT
GGACAGTCATTATTGCATGGACAGTTGATCCCCACAACTGGTCCAGTAAGAATAAATACTGCTCGTCCAGGTGGTGGTCGACCAGGCTGG
GAACATTCCAACAAACTTGGCTATCTGGTTTCTCCACCACAACAAATTAGAAGAGGGGAGAGGAGCTGCTACAGAAGTATAAACCGTGGG
CGACACCACAGCGAAAGATCACAGAGGACTCAAGGCCCGTCACTACCAGCAACTCCAGTCTTTGTACCTGTTCCACCACCTCCTTTGTAT
CCGCCTCCTCCCCATACACTTCCTCTCCCTCCGGGTGTTCCTCCTCCACAGTTTTCTCCTCAGTTTCCTCCTGGCCAGCCACCACCCGCT
GGGTATAGTGTCCCTCCTCCAGGGTTTCCTCCAGCTCCTGCCAATTTATCAACACCTTGGGTATCATCAGGAGTGCAGACAGCTCATTCA
AATACCATCCCAACAACACAAGCACCACCTTTGTCCAGGGAAGAATTCTATAGAGAGCAGCGACGACTAAAAGAAGAGTCTAAATCTCCC
TATAGTGGTTCTTCGTATTCAAGAAGTTCATATACTTATTCTAAATCAAGATCTGGTTCAACACGTTCACGCTCTTATTCTCGATCATTC
AGCCGCTCACATTCTCGTTCCTATTCACGGTCACCTCCATACCCCAGAAGAGGCAGAGGCAAGAGCCGCAATTACCGTTCACGGTCTAGA
TCTCATGGATATCATCGATCTAGGTCAAGGTCACCCCCTTACAGACGCTATCATTCACGATCAAGATCTCCTCAAGCGTTTAGGGGACAG
TCTCCTAATAAACGTAATGTACCTCAAGGGGAAACAGAACGTGAATATTTTAATAGATACAGAGAAGTTCCACCACCATATGACATGAAA
GCATATTATGGGAGAAGTGTTGACTTTAGAGACCCATTTGAAAAAGAACGCTACCGAGAATGGGAGAGAAAATATAGAGAGTGGTATGAA
AAATATTATAAAGGTTATGCTGCTGGAGCACAGCCTAGACCCTCAGCAAATAGAGAGAACTTTTCTCCAGAGAGATTTTTGCCACTTAAC
ATCAGGAATTCTCCCTTCACAAGAGGCCGCAGAGAAGACTATGTTGGTGGGCAAAGTCATAGAAGTCGAAACATAGGTAGCAACTATCCA
GAAAAGCTTTCAGCAAGAGATGGTCACAATCAGAAGGATAATACAAAGTCAAAAGAGAAGGAGAGTGAAAACGCTCCAGGAGATGGTAAA
GGAAATAAGCATAAGAAACACAGAAAAAGAAGAAAAGGGGAGGAAAGTGAGGGTTTTCTGAACCCAGAGTTATTAGAGACTTCTAGGAAA
TCAAGAGAACCTACAGGTGTTGAAGAAAATAAAACAGACTCATTGTTTGTTCTCCCAAGTAGAGATGATGCCACACCTGTTAGAGATGAA
CCAATGGATGCAGAATCAATCACTTTTAAATCAGTGTCTGAAAAAGACAAGAGAGAAAGGGATAAACCAAAAGCAAAGGGTGATAAAACC
AAACGGAAGAATGATGGATCTGCTGTGTCCAAAAAAGAAAATATTGTAAAACCTGCTAAAGGACCCCAAGAAAAAGTAGATGGAGAACGT
GAGAGATCTCCTCGATCTGAACCTCCAATTAAAAAAGCCAAAGAGGAGACTCCGAAGACTGACAATACTAAATCATCATCTTCCTCTCAG
AAGGATGAAAAAATCACTGGAACCCCCAGAAAAGCTCACTCTAAATCAGCAAAAGAACACCAAGAAACAAAACCAGTCAAAGAGGAAAAA
GTGAAGAAGGACTATTCCAAAGATGTCAAATCAGAAAAGCTAACAACTAAGGAAGAAAAGGCCAAGAAGCCTAATGAGAAAAACAAACCA
CTTGATAATAAGGGAGAAAAAAGAAAAAGAAAAACTGAAGAAAAAGGCGTAGATAAAGATTTTGAGTCTTCTTCAATGAAAATCTCGAAA
CTAGAAGTGACTGAAATAGTGAAACCATCACCAAAGCGCAAAATGGAACCTGATACTGAAAAAATGGATAGGACCCCTGAAAAGGACAAA
ATTTCTTTAAGTGCGCCAGCCAAAAAAATCAAACTCAACAGAGAAACTGGGAAGAAAATTGGAAGTACAGAAAATATATCAAACACAAAA
GAACCCTCTGAAAAATTGGAGTCAACATCTAGCAAAGTTAAACAAGAAAAAGTCAAAGGAAAGGTCAGACGAAAAGTGACTGGAACTGAA
GGATCCAGCTCAACTCTGGTGGATTACACCAGTACGAGCTCAACTGGAGGCAGTCCTGTGCGGAAATCTGAAGAAAAAACAGATACAAAG
CGAACTGTGATTAAAACGATGGAAGAATATAATAATGACAATACCGCGCCAGCTGAAGATGTTATCATTATGATTCAGGTTCCTCAATCC
AAATGGGATAAAGATGACTTTGAATCTGAAGAAGAAGATGTTAAATCCACACAGCCTATATCAAGTGTAGGAAAACCTGCTAGTGTTATA
AAAAATGTTAGTACAAAGCCATCAAATATAGTCAAGTATCCTGAGAAAGAAAGTGAGCCATCCGAGAAAATTCAGAAATTCACCAAGGAC
GTGAGCCATGAAATCATACAACATGAGGTTAAAAGTTCAAAAAACTCTGCATCTAGTGAAAAAGGGAAAACCAAAGATCGAGATTATTCA
GTGTTGGAAAAGGAGAACCCTGAAAAGAGGAAGAACAGCACTCAGCCAGAGAAAGAGAGTAATTTGGACCGTCTGAATGAACAAGGAAAT
TTTAAAAGTCTGTCTCAATCTTCCAAAGAGGCTAGAACGTCAGATAAACATGATTCCACTCGTGCTTCCTCAAATAAAGACTTCACTCCC
AATAGAGACAAAAAAACTGACTATGACACCAGAGAGTATTCAAGTTCCAAACGTAGAGATGAAAAGAATGAATTAACAAGACGAAAAGAC
TCTCCTTCTCGGAATAAAGATTCTGCATCTGGACAGAAAAATAAACCAAGGGAAGAGAGAGATTTGCCTAAAAAAGGAACAGGAGATTCC
AAAAAAAGTAATTCTAGTCCCTCAAGAGACAGAAAACCTCATGATCACAAAGCCACTTATGATACTAAACGGCCAAATGAAGAGACAAAA
TCTGTAGATAAAAATCCTTGTAAGGATCGTGAGAAGCATGTATTAGAAGCAAGGAACAATAAAGAGTCAAGTGGCAATAAACTACTTTAT
ATACTTAACCCACCAGAGACACAGGTTGAAAAAGAGCAAATTACTGGGCAAATTGACAAGAGTACTGTCAAGCCTAAACCCCAGTTAAGT
CATTCCTCTAGACTTTCCTCTGACTTAACTAGAGAAACTGATGAAGCTGCTTTTGAACCAGACTATAATGAAAGTGACAGTGAAAGTAAT
GTTTCTGTAAAAGAAGAGGAATCTTCAGGAAACATTTCTAAGGACCTGAAAGATAAAATAGTGGAGAAAGCAAAAGAGAGCCTGGACACA
GCAGCAGTTGTCCAGGTGGGCATAAGCAGGAATCAGAGCCACAGCAGCCCCAGCGTCAGCCCCAGCAGAAGCCACAGTCCTTCTGGAAGC
CAGACCCGAAGCCACAGTAGCAGTGCCAGCTCAGCAGAAAGTCAGGACAGCAAGAAGAAGAAGAAAAAGAAGGAAAAGAAAAAACACAAG
AAACATAAAAAGCATAAGAAGCATAAGAAACATGCAGGCACTGAAGTGGAATTGGAAAAAAGCCAAAAACACAAACACAAGAAAAAGAAG
TCAAAGAAGAACAAAGATAAAGAGAAGGAGAAGGAGAAAGATGACCAAAAAGTGAAATCTGTCACTGTGTAAAAAGACAGATTTTTTAAA
TTGACTTAATTACTAAGTCATCTGTATTAAATTTTGTTATAATGTAAAGAGATTCAAGCCTTGTAAATAATGACATGGAAGACCCTGTGC
TGCACTTAAAATATTGCTGCTTGATTATTTGATTTTTACATCAGAGCTTTATAACACGAACTTTTGTACAGAATTGTGAGTTGTGACCAT
GTAACATGAGAGGTTTTGCTAGGGCCTATTATTTTTAACCACCATTAATTAGTTGGGGTGGAGTTTACTGTAATGTGAAATTTTCACATT
TGAATTTTTTAATTGCCTGGCAAAAGCTGATATAAGTTCTAAAATATCAGCAGAATGATTTGCTGAATTCATTACAACCCTGTTATGTCA

>39565_39565_2_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000170630_RBBP6_chr16_24557483_ENST00000348022_length(amino acids)=1726AA_BP=1657
MGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANLAE
ANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGAML
TNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCHQN
DVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQS
SLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLLHG
QLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTL
PLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSPYSGSSYS
RSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNV
PQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFT
RGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGV
EENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSE
PPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEK
RKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLE
STSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDF
ESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENP
EKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKD
SASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPET
QVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVG
ISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDK

--------------------------------------------------------------
>39565_39565_3_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000170630_RBBP6_chr16_24557483_ENST00000381039_length(transcript)=3202nt_BP=91nt
CAGGTGCCTTGGCATCTCCCAATGGGGTGGCTTTGCTCTGGGCTCCTGTTCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCTCT
GAATATACTGATGATAATGCTCTGATTCCTAAGAATTCTTCTGTAATTGTTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCAAG
ACATATGTTATAAGTCGAACTGAACCAGCGATGGCAACTACAAAAGCAATTGATGACTCTTCCGCGTCTATTTCTCTGGCCCAGCTTACA
AAGACTGCCAATCTGGCTGAAGCCAATGCTTCTGAAGAAGATAAAATTAAAGCAATGATGTCGCAATCTGGCCATGAATACGACCCAATC
AATTACATGAAGAAACCTCTAGGTCCACCACCTCCATCTTACACGTGTTTCCGTTGTGGTAAACCTGGACATTATATTAAGAATTGCCCA
ACAAATGGGGATAAAAACTTTGAATCTGGTCCTAGGATTAAAAAGAGCACTGGAATTCCCAGAAGTTTCATGATGGAAGTGAAAGATCCT
AATATGAAAGGTGCAATGCTTACCAACACTGGAAAATATGCAATACCAACTATAGATGCAGAAGCATATGCAATTGGGAAGAAAGAGAAA
CCTCCCTTCTTACCAGAGGAGCCATCTTCTTCCTCAGAAGAAGATGATCCTATCCCAGATGAATTGTTGTGTCTCATCTGCAAGGATATT
ATGACTGATGCTGTTGTGATTCCCTGCTGTGGAAACAGTTACTGTGATGAATGTATAAGAACAGCACTCCTGGAATCAGATGAGCACACA
TGTCCGACGTGTCATCAAAATGATGTTTCTCCTGATGCTTTAATTGCCAATAAATTTTTACGACAGGCTGTAAATAACTTCAAAAATGAA
ACTGGCTATACAAAAAGACTACGAAAACAGTTACCTCCTCCACCACCCCCAATACCACCTCCGAGACCACTGATTCAGAGGAACCTACAA
CCTCTGATGAGATCTCCGATATCAAGACAACAAGATCCTCTTATGATTCCAGTGACATCTTCATCAACTCACCCAGCTCCGTCTATATCT
TCATTAACTTCTAATCAGTCTTCCTTGGCCCCTCCTGTGTCTGGAAATCCGTCTTCTGCTCCAGCTCCTGTACCTGATATAACTGCAACA
GTATCCATATCAGTTCATTCAGAAAAATCAGATGGACCTTTTCGTACGAGCTCAACTGGAGGCAGTCCTGTGCGGAAATCTGAAGAAAAA
ACAGATACAAAGCGAACTGTGATTAAAACGATGGAAGAATATAATAATGACAATACCGCGCCAGCTGAAGATGTTATCATTATGATTCAG
GTTCCTCAATCCAAATGGGATAAAGATGACTTTGAATCTGAAGAAGAAGATGTTAAATCCACACAGCCTATATCAAGTGTAGGAAAACCT
GCTAGTGTTATAAAAAATGTTAGTACAAAGCCATCAAATATAGTCAAGTATCCTGAGAAAGAAAGTGAGCCATCCGAGAAAATTCAGAAA
TTCACCAAGGACGTGAGCCATGAAATCATACAACATGAGGTTAAAAGTTCAAAAAACTCTGCATCTAGTGAAAAAGGGAAAACCAAAGAT
CGAGATTATTCAGTGTTGGAAAAGGAGAACCCTGAAAAGAGGAAGAACAGCACTCAGCCAGAGAAAGAGAGTAATTTGGACCGTCTGAAT
GAACAAGGAAATTTTAAAAGTCTGTCTCAATCTTCCAAAGAGGCTAGAACGTCAGATAAACATGATTCCACTCGTGCTTCCTCAAATAAA
GACTTCACTCCCAATAGAGACAAAAAAACTGACTATGACACCAGAGAGTATTCAAGTTCCAAACGTAGAGATGAAAAGAATGAATTAACA
AGACGAAAAGACTCTCCTTCTCGGAATAAAGATTCTGCATCTGGACAGAAAAATAAACCAAGGGAAGAGAGAGATTTGCCTAAAAAAGGA
ACAGGAGATTCCAAAAAAAGTAATTCTAGTCCCTCAAGAGACAGAAAACCTCATGATCACAAAGCCACTTATGATACTAAACGGCCAAAT
GAAGAGACAAAATCTGTAGATAAAAATCCTTGTAAGGATCGTGAGAAGCATGTATTAGAAGCAAGGAACAATAAAGAGTCAAGTGGCAAT
AAACTACTTTATATACTTAACCCACCAGAGACACAGGTTGAAAAAGAGCAAATTACTGGGCAAATTGACAAGAGTACTGTCAAGCCTAAA
CCCCAGTTAAGTCATTCCTCTAGACTTTCCTCTGACTTAACTAGAGAAACTGATGAAGCTGCTTTTGAACCAGACTATAATGAAAGTGAC
AGTGAAAGTAATGTTTCTGTAAAAGAAGAGGAATCTTCAGGAAACATTTCTAAGGACCTGAAAGATAAAATAGTGGAGAAAGCAAAAGAG
AGCCTGGACACAGCAGCAGTTGTCCAGGTGGGCATAAGCAGGAATCAGAGCCACAGCAGCCCCAGCGTCAGCCCCAGCAGAAGCCACAGT
CCTTCTGGAAGCCAGACCCGAAGCCACAGTAGCAGTGCCAGCTCAGCAGAAAGTCAGGACAGCAAGAAGAAGAAGAAAAAGAAGGAAAAG
AAAAAACACAAGAAACATAAAAAGCATAAGAAGCATAAGAAACATGCAGGCACTGAAGTGGAATTGGAAAAAAGCCAAAAACACAAACAC
AAGAAAAAGAAGTCAAAGAAGAACAAAGATAAAGAGAAGGAGAAGGAGAAAGATGACCAAAAAGTGAAATCTGTCACTGTGTAAAAAGAC
AGATTTTTTAAATTGACTTAATTACTAAGTCATCTGTATTAAATTTTGTTATAATGTAAAGAGATTCAAGCCTTGTAAATAATGACATGG
AAGACCCTGTGCTGCACTTAAAATATTGCTGCTTGATTATTTGATTTTTACATCAGAGCTTTATAACACGAACTTTTGTACAGAATTGTG
AGTTGTGACCATGTAACATGAGAGGTTTTGCTAGGGCCTATTATTTTTAACCACCATTAATTAGTTGGGGTGGAGTTTACTGTAATGTGA
AATTTTCACATTTGAATTTTTTAATTGCCTGGCAAAAGCTGATATAAGTTCTAAAATATCAGCAGAATGATTTGCTGAATTCATTACAAC

>39565_39565_3_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000170630_RBBP6_chr16_24557483_ENST00000381039_length(amino acids)=920AA_BP=851
MGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANLAE
ANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGAML
TNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCHQN
DVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQS
SLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWD
KDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLE
KENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPS
RNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILN
PPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAV
VQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKK

--------------------------------------------------------------
>39565_39565_4_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000170630_RBBP6_chr16_24557483_ENST00000452655_length(transcript)=648nt_BP=91nt
CAGGTGCCTTGGCATCTCCCAATGGGGTGGCTTTGCTCTGGGCTCCTGTTCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCTCT
GAATATACTGATGATAATGCTCTGATTCCTAAGAATTCTTCTGTAATTGTTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCAAG
ACATATGTTATAAGTCGAACTGAACCAGCGATGGCAACTACAAAAGCAGTATGTAAAAACACAATCTCACACTTTTTCTACACATTGCTT
TTACCTTTATAATGTAGCAGTGAAGTAAATCATTTTAGAACTTAATATCCAACTGATCATAGTACATATTGTAAATAAAATGTATTTTGA
TGACAGCTCAGTTGAATATGGATAATATGTGGCATCACTTGCACACTTATTTTGTAGAAATGGGTAATTTGTGCCCGTAACACTGTTTCA
TATTAAATATGATAGCATTATCCCTGTATGACACTGTGTTGTACAGTTAATGTATGATCCTTTTTAGATCGTTTAGGTTTTACACTAAGG
AACATGATGACATGTTCTACATTTGTCTGTCTATAGTTAGTATTTTGTATGTATGTACAGGCTGTTGTGTGCTTTTTGTTTCTTGCAATA

>39565_39565_4_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000170630_RBBP6_chr16_24557483_ENST00000452655_length(amino acids)=86AA_BP=11

--------------------------------------------------------------
>39565_39565_5_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000395762_RBBP6_chr16_24557483_ENST00000319715_length(transcript)=5960nt_BP=329nt
CTCCGCGCCCAGGAAAGCCCCGCGCGGCGCGGGCCAGGGAAGGGCCACCCAGGGGTCCCCCACTTCCCGCTTGGGCGCCCGGACGGCGAA
TGGAGCAGGGGCGCGCAGATAATTAAAGATTTACACACAGCTGGAAGAAATCATAGAGAAGCCGGGCGTGGTGGCTCATGCCTATAATCC
CAGCACTTTTGGAGGCTGAGGCGGGCAGATCACTTGAGATCAGGAGTTCGAGACCAGCCTGGTGCCTTGGCATCTCCCAATGGGGTGGCT
TTGCTCTGGGCTCCTGTTCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCTCTGAATATACTGATGATAATGCTCTGATTCCTAA
GAATTCTTCTGTAATTGTTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCAAGACATATGTTATAAGTCGAACTGAACCAGCGAT
GGCAACTACAAAAGCAATTGATGACTCTTCCGCGTCTATTTCTCTGGCCCAGCTTACAAAGACTGCCAATCTGGCTGAAGCCAATGCTTC
TGAAGAAGATAAAATTAAAGCAATGATGTCGCAATCTGGCCATGAATACGACCCAATCAATTACATGAAGAAACCTCTAGGTCCACCACC
TCCATCTTACACGTGTTTCCGTTGTGGTAAACCTGGACATTATATTAAGAATTGCCCAACAAATGGGGATAAAAACTTTGAATCTGGTCC
TAGGATTAAAAAGAGCACTGGAATTCCCAGAAGTTTCATGATGGAAGTGAAAGATCCTAATATGAAAGGTGCAATGCTTACCAACACTGG
AAAATATGCAATACCAACTATAGATGCAGAAGCATATGCAATTGGGAAGAAAGAGAAACCTCCCTTCTTACCAGAGGAGCCATCTTCTTC
CTCAGAAGAAGATGATCCTATCCCAGATGAATTGTTGTGTCTCATCTGCAAGGATATTATGACTGATGCTGTTGTGATTCCCTGCTGTGG
AAACAGTTACTGTGATGAATGTATAAGAACAGCACTCCTGGAATCAGATGAGCACACATGTCCGACGTGTCATCAAAATGATGTTTCTCC
TGATGCTTTAATTGCCAATAAATTTTTACGACAGGCTGTAAATAACTTCAAAAATGAAACTGGCTATACAAAAAGACTACGAAAACAGTT
ACCTCCTCCACCACCCCCAATACCACCTCCGAGACCACTGATTCAGAGGAACCTACAACCTCTGATGAGATCTCCGATATCAAGACAACA
AGATCCTCTTATGATTCCAGTGACATCTTCATCAACTCACCCAGCTCCGTCTATATCTTCATTAACTTCTAATCAGTCTTCCTTGGCCCC
TCCTGTGTCTGGAAATCCGTCTTCTGCTCCAGCTCCTGTACCTGATATAACTGCAACAGTATCCATATCAGTTCATTCAGAAAAATCAGA
TGGACCTTTTCGGGATTCTGATAATAAAATATTGCCAGCTGCAGCTCTTGCATCAGAGCACTCAAAGGGAACCTCCTCAATTGCAATTAC
CGCTCTTATGGAAGAGAAGGGTTACCAGGTGCCTGTTCTTGGAACCCCATCTTTGCTTGGACAGTCATTATTGCATGGACAGTTGATCCC
CACAACTGGTCCAGTAAGAATAAATACTGCTCGTCCAGGTGGTGGTCGACCAGGCTGGGAACATTCCAACAAACTTGGCTATCTGGTTTC
TCCACCACAACAAATTAGAAGAGGGGAGAGGAGCTGCTACAGAAGTATAAACCGTGGGCGACACCACAGCGAAAGATCACAGAGGACTCA
AGGCCCGTCACTACCAGCAACTCCAGTCTTTGTACCTGTTCCACCACCTCCTTTGTATCCGCCTCCTCCCCATACACTTCCTCTCCCTCC
GGGTGTTCCTCCTCCACAGTTTTCTCCTCAGTTTCCTCCTGGCCAGCCACCACCCGCTGGGTATAGTGTCCCTCCTCCAGGGTTTCCTCC
AGCTCCTGCCAATTTATCAACACCTTGGGTATCATCAGGAGTGCAGACAGCTCATTCAAATACCATCCCAACAACACAAGCACCACCTTT
GTCCAGGGAAGAATTCTATAGAGAGCAGCGACGACTAAAAGAAGAGGAAAAGAAAAAGTCCAAGCTAGATGAGTTTACAAATGATTTTGC
TAAGGAATTGATGGAATACAAAAAGATTCAAAAGGAGCGTAGGCGCTCATTTTCCAGGTCTAAATCTCCCTATAGTGGTTCTTCGTATTC
AAGAAGTTCATATACTTATTCTAAATCAAGATCTGGTTCAACACGTTCACGCTCTTATTCTCGATCATTCAGCCGCTCACATTCTCGTTC
CTATTCACGGTCACCTCCATACCCCAGAAGAGGCAGAGGCAAGAGCCGCAATTACCGTTCACGGTCTAGATCTCATGGATATCATCGATC
TAGGTCAAGGTCACCCCCTTACAGACGCTATCATTCACGATCAAGATCTCCTCAAGCGTTTAGGGGACAGTCTCCTAATAAACGTAATGT
ACCTCAAGGGGAAACAGAACGTGAATATTTTAATAGATACAGAGAAGTTCCACCACCATATGACATGAAAGCATATTATGGGAGAAGTGT
TGACTTTAGAGACCCATTTGAAAAAGAACGCTACCGAGAATGGGAGAGAAAATATAGAGAGTGGTATGAAAAATATTATAAAGGTTATGC
TGCTGGAGCACAGCCTAGACCCTCAGCAAATAGAGAGAACTTTTCTCCAGAGAGATTTTTGCCACTTAACATCAGGAATTCTCCCTTCAC
AAGAGGCCGCAGAGAAGACTATGTTGGTGGGCAAAGTCATAGAAGTCGAAACATAGGTAGCAACTATCCAGAAAAGCTTTCAGCAAGAGA
TGGTCACAATCAGAAGGATAATACAAAGTCAAAAGAGAAGGAGAGTGAAAACGCTCCAGGAGATGGTAAAGGAAATAAGCATAAGAAACA
CAGAAAAAGAAGAAAAGGGGAGGAAAGTGAGGGTTTTCTGAACCCAGAGTTATTAGAGACTTCTAGGAAATCAAGAGAACCTACAGGTGT
TGAAGAAAATAAAACAGACTCATTGTTTGTTCTCCCAAGTAGAGATGATGCCACACCTGTTAGAGATGAACCAATGGATGCAGAATCAAT
CACTTTTAAATCAGTGTCTGAAAAAGACAAGAGAGAAAGGGATAAACCAAAAGCAAAGGGTGATAAAACCAAACGGAAGAATGATGGATC
TGCTGTGTCCAAAAAAGAAAATATTGTAAAACCTGCTAAAGGACCCCAAGAAAAAGTAGATGGAGAACGTGAGAGATCTCCTCGATCTGA
ACCTCCAATTAAAAAAGCCAAAGAGGAGACTCCGAAGACTGACAATACTAAATCATCATCTTCCTCTCAGAAGGATGAAAAAATCACTGG
AACCCCCAGAAAAGCTCACTCTAAATCAGCAAAAGAACACCAAGAAACAAAACCAGTCAAAGAGGAAAAAGTGAAGAAGGACTATTCCAA
AGATGTCAAATCAGAAAAGCTAACAACTAAGGAAGAAAAGGCCAAGAAGCCTAATGAGAAAAACAAACCACTTGATAATAAGGGAGAAAA
AAGAAAAAGAAAAACTGAAGAAAAAGGCGTAGATAAAGATTTTGAGTCTTCTTCAATGAAAATCTCGAAACTAGAAGTGACTGAAATAGT
GAAACCATCACCAAAGCGCAAAATGGAACCTGATACTGAAAAAATGGATAGGACCCCTGAAAAGGACAAAATTTCTTTAAGTGCGCCAGC
CAAAAAAATCAAACTCAACAGAGAAACTGGGAAGAAAATTGGAAGTACAGAAAATATATCAAACACAAAAGAACCCTCTGAAAAATTGGA
GTCAACATCTAGCAAAGTTAAACAAGAAAAAGTCAAAGGAAAGGTCAGACGAAAAGTGACTGGAACTGAAGGATCCAGCTCAACTCTGGT
GGATTACACCAGTACGAGCTCAACTGGAGGCAGTCCTGTGCGGAAATCTGAAGAAAAAACAGATACAAAGCGAACTGTGATTAAAACGAT
GGAAGAATATAATAATGACAATACCGCGCCAGCTGAAGATGTTATCATTATGATTCAGGTTCCTCAATCCAAATGGGATAAAGATGACTT
TGAATCTGAAGAAGAAGATGTTAAATCCACACAGCCTATATCAAGTGTAGGAAAACCTGCTAGTGTTATAAAAAATGTTAGTACAAAGCC
ATCAAATATAGTCAAGTATCCTGAGAAAGAAAGTGAGCCATCCGAGAAAATTCAGAAATTCACCAAGGACGTGAGCCATGAAATCATACA
ACATGAGGTTAAAAGTTCAAAAAACTCTGCATCTAGTGAAAAAGGGAAAACCAAAGATCGAGATTATTCAGTGTTGGAAAAGGAGAACCC
TGAAAAGAGGAAGAACAGCACTCAGCCAGAGAAAGAGAGTAATTTGGACCGTCTGAATGAACAAGGAAATTTTAAAAGTCTGTCTCAATC
TTCCAAAGAGGCTAGAACGTCAGATAAACATGATTCCACTCGTGCTTCCTCAAATAAAGACTTCACTCCCAATAGAGACAAAAAAACTGA
CTATGACACCAGAGAGTATTCAAGTTCCAAACGTAGAGATGAAAAGAATGAATTAACAAGACGAAAAGACTCTCCTTCTCGGAATAAAGA
TTCTGCATCTGGACAGAAAAATAAACCAAGGGAAGAGAGAGATTTGCCTAAAAAAGGAACAGGAGATTCCAAAAAAAGTAATTCTAGTCC
CTCAAGAGACAGAAAACCTCATGATCACAAAGCCACTTATGATACTAAACGGCCAAATGAAGAGACAAAATCTGTAGATAAAAATCCTTG
TAAGGATCGTGAGAAGCATGTATTAGAAGCAAGGAACAATAAAGAGTCAAGTGGCAATAAACTACTTTATATACTTAACCCACCAGAGAC
ACAGGTTGAAAAAGAGCAAATTACTGGGCAAATTGACAAGAGTACTGTCAAGCCTAAACCCCAGTTAAGTCATTCCTCTAGACTTTCCTC
TGACTTAACTAGAGAAACTGATGAAGCTGCTTTTGAACCAGACTATAATGAAAGTGACAGTGAAAGTAATGTTTCTGTAAAAGAAGAGGA
ATCTTCAGGAAACATTTCTAAGGACCTGAAAGATAAAATAGTGGAGAAAGCAAAAGAGAGCCTGGACACAGCAGCAGTTGTCCAGGTGGG
CATAAGCAGGAATCAGAGCCACAGCAGCCCCAGCGTCAGCCCCAGCAGAAGCCACAGTCCTTCTGGAAGCCAGACCCGAAGCCACAGTAG
CAGTGCCAGCTCAGCAGAAAGTCAGGACAGCAAGAAGAAGAAGAAAAAGAAGGAAAAGAAAAAACACAAGAAACATAAAAAGCATAAGAA
GCATAAGAAACATGCAGGCACTGAAGTGGAATTGGAAAAAAGCCAAAAACACAAACACAAGAAAAAGAAGTCAAAGAAGAACAAAGATAA
AGAGAAGGAGAAGGAGAAAGATGACCAAAAAGTGAAATCTGTCACTGTGTAAAAAGACAGATTTTTTAAATTGACTTAATTACTAAGTCA
TCTGTATTAAATTTTGTTATAATGTAAAGAGATTCAAGCCTTGTAAATAATGACATGGAAGACCCTGTGCTGCACTTAAAATATTGCTGC
TTGATTATTTGATTTTTACATCAGAGCTTTATAACACGAACTTTTGTACAGAATTGTGAGTTGTGACCATGTAACATGAGAGGTTTTGCT
AGGGCCTATTATTTTTAACCACCATTAATTAGTTGGGGTGGAGTTTACTGTAATGTGAAATTTTCACATTTGAATTTTTTAATTGCCTGG
CAAAAGCTGATATAAGTTCTAAAATATCAGCAGAATGATTTGCTGAATTCATTACAACCCTGTTATGTCACTTTTTGATTACAATAAAAG

>39565_39565_5_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000395762_RBBP6_chr16_24557483_ENST00000319715_length(amino acids)=1767AA_BP=1698
MVPWHLPMGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLT
KTANLAEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDP
NMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHT
CPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSIS
SLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLL
GQSLLHGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLY
PPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKK
SKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYR
SRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYR
EWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAP
GDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAK
GDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPV
KEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTP
EKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEK
TDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQK
FTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNK
DFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPN
EETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESD
SESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEK

--------------------------------------------------------------
>39565_39565_6_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000395762_RBBP6_chr16_24557483_ENST00000348022_length(transcript)=5858nt_BP=329nt
CTCCGCGCCCAGGAAAGCCCCGCGCGGCGCGGGCCAGGGAAGGGCCACCCAGGGGTCCCCCACTTCCCGCTTGGGCGCCCGGACGGCGAA
TGGAGCAGGGGCGCGCAGATAATTAAAGATTTACACACAGCTGGAAGAAATCATAGAGAAGCCGGGCGTGGTGGCTCATGCCTATAATCC
CAGCACTTTTGGAGGCTGAGGCGGGCAGATCACTTGAGATCAGGAGTTCGAGACCAGCCTGGTGCCTTGGCATCTCCCAATGGGGTGGCT
TTGCTCTGGGCTCCTGTTCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCTCTGAATATACTGATGATAATGCTCTGATTCCTAA
GAATTCTTCTGTAATTGTTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCAAGACATATGTTATAAGTCGAACTGAACCAGCGAT
GGCAACTACAAAAGCAATTGATGACTCTTCCGCGTCTATTTCTCTGGCCCAGCTTACAAAGACTGCCAATCTGGCTGAAGCCAATGCTTC
TGAAGAAGATAAAATTAAAGCAATGATGTCGCAATCTGGCCATGAATACGACCCAATCAATTACATGAAGAAACCTCTAGGTCCACCACC
TCCATCTTACACGTGTTTCCGTTGTGGTAAACCTGGACATTATATTAAGAATTGCCCAACAAATGGGGATAAAAACTTTGAATCTGGTCC
TAGGATTAAAAAGAGCACTGGAATTCCCAGAAGTTTCATGATGGAAGTGAAAGATCCTAATATGAAAGGTGCAATGCTTACCAACACTGG
AAAATATGCAATACCAACTATAGATGCAGAAGCATATGCAATTGGGAAGAAAGAGAAACCTCCCTTCTTACCAGAGGAGCCATCTTCTTC
CTCAGAAGAAGATGATCCTATCCCAGATGAATTGTTGTGTCTCATCTGCAAGGATATTATGACTGATGCTGTTGTGATTCCCTGCTGTGG
AAACAGTTACTGTGATGAATGTATAAGAACAGCACTCCTGGAATCAGATGAGCACACATGTCCGACGTGTCATCAAAATGATGTTTCTCC
TGATGCTTTAATTGCCAATAAATTTTTACGACAGGCTGTAAATAACTTCAAAAATGAAACTGGCTATACAAAAAGACTACGAAAACAGTT
ACCTCCTCCACCACCCCCAATACCACCTCCGAGACCACTGATTCAGAGGAACCTACAACCTCTGATGAGATCTCCGATATCAAGACAACA
AGATCCTCTTATGATTCCAGTGACATCTTCATCAACTCACCCAGCTCCGTCTATATCTTCATTAACTTCTAATCAGTCTTCCTTGGCCCC
TCCTGTGTCTGGAAATCCGTCTTCTGCTCCAGCTCCTGTACCTGATATAACTGCAACAGTATCCATATCAGTTCATTCAGAAAAATCAGA
TGGACCTTTTCGGGATTCTGATAATAAAATATTGCCAGCTGCAGCTCTTGCATCAGAGCACTCAAAGGGAACCTCCTCAATTGCAATTAC
CGCTCTTATGGAAGAGAAGGGTTACCAGGTGCCTGTTCTTGGAACCCCATCTTTGCTTGGACAGTCATTATTGCATGGACAGTTGATCCC
CACAACTGGTCCAGTAAGAATAAATACTGCTCGTCCAGGTGGTGGTCGACCAGGCTGGGAACATTCCAACAAACTTGGCTATCTGGTTTC
TCCACCACAACAAATTAGAAGAGGGGAGAGGAGCTGCTACAGAAGTATAAACCGTGGGCGACACCACAGCGAAAGATCACAGAGGACTCA
AGGCCCGTCACTACCAGCAACTCCAGTCTTTGTACCTGTTCCACCACCTCCTTTGTATCCGCCTCCTCCCCATACACTTCCTCTCCCTCC
GGGTGTTCCTCCTCCACAGTTTTCTCCTCAGTTTCCTCCTGGCCAGCCACCACCCGCTGGGTATAGTGTCCCTCCTCCAGGGTTTCCTCC
AGCTCCTGCCAATTTATCAACACCTTGGGTATCATCAGGAGTGCAGACAGCTCATTCAAATACCATCCCAACAACACAAGCACCACCTTT
GTCCAGGGAAGAATTCTATAGAGAGCAGCGACGACTAAAAGAAGAGTCTAAATCTCCCTATAGTGGTTCTTCGTATTCAAGAAGTTCATA
TACTTATTCTAAATCAAGATCTGGTTCAACACGTTCACGCTCTTATTCTCGATCATTCAGCCGCTCACATTCTCGTTCCTATTCACGGTC
ACCTCCATACCCCAGAAGAGGCAGAGGCAAGAGCCGCAATTACCGTTCACGGTCTAGATCTCATGGATATCATCGATCTAGGTCAAGGTC
ACCCCCTTACAGACGCTATCATTCACGATCAAGATCTCCTCAAGCGTTTAGGGGACAGTCTCCTAATAAACGTAATGTACCTCAAGGGGA
AACAGAACGTGAATATTTTAATAGATACAGAGAAGTTCCACCACCATATGACATGAAAGCATATTATGGGAGAAGTGTTGACTTTAGAGA
CCCATTTGAAAAAGAACGCTACCGAGAATGGGAGAGAAAATATAGAGAGTGGTATGAAAAATATTATAAAGGTTATGCTGCTGGAGCACA
GCCTAGACCCTCAGCAAATAGAGAGAACTTTTCTCCAGAGAGATTTTTGCCACTTAACATCAGGAATTCTCCCTTCACAAGAGGCCGCAG
AGAAGACTATGTTGGTGGGCAAAGTCATAGAAGTCGAAACATAGGTAGCAACTATCCAGAAAAGCTTTCAGCAAGAGATGGTCACAATCA
GAAGGATAATACAAAGTCAAAAGAGAAGGAGAGTGAAAACGCTCCAGGAGATGGTAAAGGAAATAAGCATAAGAAACACAGAAAAAGAAG
AAAAGGGGAGGAAAGTGAGGGTTTTCTGAACCCAGAGTTATTAGAGACTTCTAGGAAATCAAGAGAACCTACAGGTGTTGAAGAAAATAA
AACAGACTCATTGTTTGTTCTCCCAAGTAGAGATGATGCCACACCTGTTAGAGATGAACCAATGGATGCAGAATCAATCACTTTTAAATC
AGTGTCTGAAAAAGACAAGAGAGAAAGGGATAAACCAAAAGCAAAGGGTGATAAAACCAAACGGAAGAATGATGGATCTGCTGTGTCCAA
AAAAGAAAATATTGTAAAACCTGCTAAAGGACCCCAAGAAAAAGTAGATGGAGAACGTGAGAGATCTCCTCGATCTGAACCTCCAATTAA
AAAAGCCAAAGAGGAGACTCCGAAGACTGACAATACTAAATCATCATCTTCCTCTCAGAAGGATGAAAAAATCACTGGAACCCCCAGAAA
AGCTCACTCTAAATCAGCAAAAGAACACCAAGAAACAAAACCAGTCAAAGAGGAAAAAGTGAAGAAGGACTATTCCAAAGATGTCAAATC
AGAAAAGCTAACAACTAAGGAAGAAAAGGCCAAGAAGCCTAATGAGAAAAACAAACCACTTGATAATAAGGGAGAAAAAAGAAAAAGAAA
AACTGAAGAAAAAGGCGTAGATAAAGATTTTGAGTCTTCTTCAATGAAAATCTCGAAACTAGAAGTGACTGAAATAGTGAAACCATCACC
AAAGCGCAAAATGGAACCTGATACTGAAAAAATGGATAGGACCCCTGAAAAGGACAAAATTTCTTTAAGTGCGCCAGCCAAAAAAATCAA
ACTCAACAGAGAAACTGGGAAGAAAATTGGAAGTACAGAAAATATATCAAACACAAAAGAACCCTCTGAAAAATTGGAGTCAACATCTAG
CAAAGTTAAACAAGAAAAAGTCAAAGGAAAGGTCAGACGAAAAGTGACTGGAACTGAAGGATCCAGCTCAACTCTGGTGGATTACACCAG
TACGAGCTCAACTGGAGGCAGTCCTGTGCGGAAATCTGAAGAAAAAACAGATACAAAGCGAACTGTGATTAAAACGATGGAAGAATATAA
TAATGACAATACCGCGCCAGCTGAAGATGTTATCATTATGATTCAGGTTCCTCAATCCAAATGGGATAAAGATGACTTTGAATCTGAAGA
AGAAGATGTTAAATCCACACAGCCTATATCAAGTGTAGGAAAACCTGCTAGTGTTATAAAAAATGTTAGTACAAAGCCATCAAATATAGT
CAAGTATCCTGAGAAAGAAAGTGAGCCATCCGAGAAAATTCAGAAATTCACCAAGGACGTGAGCCATGAAATCATACAACATGAGGTTAA
AAGTTCAAAAAACTCTGCATCTAGTGAAAAAGGGAAAACCAAAGATCGAGATTATTCAGTGTTGGAAAAGGAGAACCCTGAAAAGAGGAA
GAACAGCACTCAGCCAGAGAAAGAGAGTAATTTGGACCGTCTGAATGAACAAGGAAATTTTAAAAGTCTGTCTCAATCTTCCAAAGAGGC
TAGAACGTCAGATAAACATGATTCCACTCGTGCTTCCTCAAATAAAGACTTCACTCCCAATAGAGACAAAAAAACTGACTATGACACCAG
AGAGTATTCAAGTTCCAAACGTAGAGATGAAAAGAATGAATTAACAAGACGAAAAGACTCTCCTTCTCGGAATAAAGATTCTGCATCTGG
ACAGAAAAATAAACCAAGGGAAGAGAGAGATTTGCCTAAAAAAGGAACAGGAGATTCCAAAAAAAGTAATTCTAGTCCCTCAAGAGACAG
AAAACCTCATGATCACAAAGCCACTTATGATACTAAACGGCCAAATGAAGAGACAAAATCTGTAGATAAAAATCCTTGTAAGGATCGTGA
GAAGCATGTATTAGAAGCAAGGAACAATAAAGAGTCAAGTGGCAATAAACTACTTTATATACTTAACCCACCAGAGACACAGGTTGAAAA
AGAGCAAATTACTGGGCAAATTGACAAGAGTACTGTCAAGCCTAAACCCCAGTTAAGTCATTCCTCTAGACTTTCCTCTGACTTAACTAG
AGAAACTGATGAAGCTGCTTTTGAACCAGACTATAATGAAAGTGACAGTGAAAGTAATGTTTCTGTAAAAGAAGAGGAATCTTCAGGAAA
CATTTCTAAGGACCTGAAAGATAAAATAGTGGAGAAAGCAAAAGAGAGCCTGGACACAGCAGCAGTTGTCCAGGTGGGCATAAGCAGGAA
TCAGAGCCACAGCAGCCCCAGCGTCAGCCCCAGCAGAAGCCACAGTCCTTCTGGAAGCCAGACCCGAAGCCACAGTAGCAGTGCCAGCTC
AGCAGAAAGTCAGGACAGCAAGAAGAAGAAGAAAAAGAAGGAAAAGAAAAAACACAAGAAACATAAAAAGCATAAGAAGCATAAGAAACA
TGCAGGCACTGAAGTGGAATTGGAAAAAAGCCAAAAACACAAACACAAGAAAAAGAAGTCAAAGAAGAACAAAGATAAAGAGAAGGAGAA
GGAGAAAGATGACCAAAAAGTGAAATCTGTCACTGTGTAAAAAGACAGATTTTTTAAATTGACTTAATTACTAAGTCATCTGTATTAAAT
TTTGTTATAATGTAAAGAGATTCAAGCCTTGTAAATAATGACATGGAAGACCCTGTGCTGCACTTAAAATATTGCTGCTTGATTATTTGA
TTTTTACATCAGAGCTTTATAACACGAACTTTTGTACAGAATTGTGAGTTGTGACCATGTAACATGAGAGGTTTTGCTAGGGCCTATTAT
TTTTAACCACCATTAATTAGTTGGGGTGGAGTTTACTGTAATGTGAAATTTTCACATTTGAATTTTTTAATTGCCTGGCAAAAGCTGATA
TAAGTTCTAAAATATCAGCAGAATGATTTGCTGAATTCATTACAACCCTGTTATGTCACTTTTTGATTACAATAAAAGTTTTCAGTAAAC

>39565_39565_6_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000395762_RBBP6_chr16_24557483_ENST00000348022_length(amino acids)=1733AA_BP=1664
MVPWHLPMGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLT
KTANLAEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDP
NMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHT
CPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSIS
SLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLL
GQSLLHGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLY
PPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSP
YSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQ
SPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLN
IRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRK
SREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGER
ERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKP
LDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTK
EPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQS
KWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYS
VLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKD
SPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLY
ILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDT
AAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKK

--------------------------------------------------------------
>39565_39565_7_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000395762_RBBP6_chr16_24557483_ENST00000381039_length(transcript)=3440nt_BP=329nt
CTCCGCGCCCAGGAAAGCCCCGCGCGGCGCGGGCCAGGGAAGGGCCACCCAGGGGTCCCCCACTTCCCGCTTGGGCGCCCGGACGGCGAA
TGGAGCAGGGGCGCGCAGATAATTAAAGATTTACACACAGCTGGAAGAAATCATAGAGAAGCCGGGCGTGGTGGCTCATGCCTATAATCC
CAGCACTTTTGGAGGCTGAGGCGGGCAGATCACTTGAGATCAGGAGTTCGAGACCAGCCTGGTGCCTTGGCATCTCCCAATGGGGTGGCT
TTGCTCTGGGCTCCTGTTCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCTCTGAATATACTGATGATAATGCTCTGATTCCTAA
GAATTCTTCTGTAATTGTTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCAAGACATATGTTATAAGTCGAACTGAACCAGCGAT
GGCAACTACAAAAGCAATTGATGACTCTTCCGCGTCTATTTCTCTGGCCCAGCTTACAAAGACTGCCAATCTGGCTGAAGCCAATGCTTC
TGAAGAAGATAAAATTAAAGCAATGATGTCGCAATCTGGCCATGAATACGACCCAATCAATTACATGAAGAAACCTCTAGGTCCACCACC
TCCATCTTACACGTGTTTCCGTTGTGGTAAACCTGGACATTATATTAAGAATTGCCCAACAAATGGGGATAAAAACTTTGAATCTGGTCC
TAGGATTAAAAAGAGCACTGGAATTCCCAGAAGTTTCATGATGGAAGTGAAAGATCCTAATATGAAAGGTGCAATGCTTACCAACACTGG
AAAATATGCAATACCAACTATAGATGCAGAAGCATATGCAATTGGGAAGAAAGAGAAACCTCCCTTCTTACCAGAGGAGCCATCTTCTTC
CTCAGAAGAAGATGATCCTATCCCAGATGAATTGTTGTGTCTCATCTGCAAGGATATTATGACTGATGCTGTTGTGATTCCCTGCTGTGG
AAACAGTTACTGTGATGAATGTATAAGAACAGCACTCCTGGAATCAGATGAGCACACATGTCCGACGTGTCATCAAAATGATGTTTCTCC
TGATGCTTTAATTGCCAATAAATTTTTACGACAGGCTGTAAATAACTTCAAAAATGAAACTGGCTATACAAAAAGACTACGAAAACAGTT
ACCTCCTCCACCACCCCCAATACCACCTCCGAGACCACTGATTCAGAGGAACCTACAACCTCTGATGAGATCTCCGATATCAAGACAACA
AGATCCTCTTATGATTCCAGTGACATCTTCATCAACTCACCCAGCTCCGTCTATATCTTCATTAACTTCTAATCAGTCTTCCTTGGCCCC
TCCTGTGTCTGGAAATCCGTCTTCTGCTCCAGCTCCTGTACCTGATATAACTGCAACAGTATCCATATCAGTTCATTCAGAAAAATCAGA
TGGACCTTTTCGTACGAGCTCAACTGGAGGCAGTCCTGTGCGGAAATCTGAAGAAAAAACAGATACAAAGCGAACTGTGATTAAAACGAT
GGAAGAATATAATAATGACAATACCGCGCCAGCTGAAGATGTTATCATTATGATTCAGGTTCCTCAATCCAAATGGGATAAAGATGACTT
TGAATCTGAAGAAGAAGATGTTAAATCCACACAGCCTATATCAAGTGTAGGAAAACCTGCTAGTGTTATAAAAAATGTTAGTACAAAGCC
ATCAAATATAGTCAAGTATCCTGAGAAAGAAAGTGAGCCATCCGAGAAAATTCAGAAATTCACCAAGGACGTGAGCCATGAAATCATACA
ACATGAGGTTAAAAGTTCAAAAAACTCTGCATCTAGTGAAAAAGGGAAAACCAAAGATCGAGATTATTCAGTGTTGGAAAAGGAGAACCC
TGAAAAGAGGAAGAACAGCACTCAGCCAGAGAAAGAGAGTAATTTGGACCGTCTGAATGAACAAGGAAATTTTAAAAGTCTGTCTCAATC
TTCCAAAGAGGCTAGAACGTCAGATAAACATGATTCCACTCGTGCTTCCTCAAATAAAGACTTCACTCCCAATAGAGACAAAAAAACTGA
CTATGACACCAGAGAGTATTCAAGTTCCAAACGTAGAGATGAAAAGAATGAATTAACAAGACGAAAAGACTCTCCTTCTCGGAATAAAGA
TTCTGCATCTGGACAGAAAAATAAACCAAGGGAAGAGAGAGATTTGCCTAAAAAAGGAACAGGAGATTCCAAAAAAAGTAATTCTAGTCC
CTCAAGAGACAGAAAACCTCATGATCACAAAGCCACTTATGATACTAAACGGCCAAATGAAGAGACAAAATCTGTAGATAAAAATCCTTG
TAAGGATCGTGAGAAGCATGTATTAGAAGCAAGGAACAATAAAGAGTCAAGTGGCAATAAACTACTTTATATACTTAACCCACCAGAGAC
ACAGGTTGAAAAAGAGCAAATTACTGGGCAAATTGACAAGAGTACTGTCAAGCCTAAACCCCAGTTAAGTCATTCCTCTAGACTTTCCTC
TGACTTAACTAGAGAAACTGATGAAGCTGCTTTTGAACCAGACTATAATGAAAGTGACAGTGAAAGTAATGTTTCTGTAAAAGAAGAGGA
ATCTTCAGGAAACATTTCTAAGGACCTGAAAGATAAAATAGTGGAGAAAGCAAAAGAGAGCCTGGACACAGCAGCAGTTGTCCAGGTGGG
CATAAGCAGGAATCAGAGCCACAGCAGCCCCAGCGTCAGCCCCAGCAGAAGCCACAGTCCTTCTGGAAGCCAGACCCGAAGCCACAGTAG
CAGTGCCAGCTCAGCAGAAAGTCAGGACAGCAAGAAGAAGAAGAAAAAGAAGGAAAAGAAAAAACACAAGAAACATAAAAAGCATAAGAA
GCATAAGAAACATGCAGGCACTGAAGTGGAATTGGAAAAAAGCCAAAAACACAAACACAAGAAAAAGAAGTCAAAGAAGAACAAAGATAA
AGAGAAGGAGAAGGAGAAAGATGACCAAAAAGTGAAATCTGTCACTGTGTAAAAAGACAGATTTTTTAAATTGACTTAATTACTAAGTCA
TCTGTATTAAATTTTGTTATAATGTAAAGAGATTCAAGCCTTGTAAATAATGACATGGAAGACCCTGTGCTGCACTTAAAATATTGCTGC
TTGATTATTTGATTTTTACATCAGAGCTTTATAACACGAACTTTTGTACAGAATTGTGAGTTGTGACCATGTAACATGAGAGGTTTTGCT
AGGGCCTATTATTTTTAACCACCATTAATTAGTTGGGGTGGAGTTTACTGTAATGTGAAATTTTCACATTTGAATTTTTTAATTGCCTGG
CAAAAGCTGATATAAGTTCTAAAATATCAGCAGAATGATTTGCTGAATTCATTACAACCCTGTTATGTCACTTTTTGATTACAATAAAAG

>39565_39565_7_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000395762_RBBP6_chr16_24557483_ENST00000381039_length(amino acids)=927AA_BP=858
MVPWHLPMGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLT
KTANLAEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDP
NMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHT
CPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSIS
SLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQ
VPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKD
RDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELT
RRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGN
KLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKE
SLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKH

--------------------------------------------------------------
>39565_39565_8_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000395762_RBBP6_chr16_24557483_ENST00000452655_length(transcript)=886nt_BP=329nt
CTCCGCGCCCAGGAAAGCCCCGCGCGGCGCGGGCCAGGGAAGGGCCACCCAGGGGTCCCCCACTTCCCGCTTGGGCGCCCGGACGGCGAA
TGGAGCAGGGGCGCGCAGATAATTAAAGATTTACACACAGCTGGAAGAAATCATAGAGAAGCCGGGCGTGGTGGCTCATGCCTATAATCC
CAGCACTTTTGGAGGCTGAGGCGGGCAGATCACTTGAGATCAGGAGTTCGAGACCAGCCTGGTGCCTTGGCATCTCCCAATGGGGTGGCT
TTGCTCTGGGCTCCTGTTCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCTCTGAATATACTGATGATAATGCTCTGATTCCTAA
GAATTCTTCTGTAATTGTTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCAAGACATATGTTATAAGTCGAACTGAACCAGCGAT
GGCAACTACAAAAGCAGTATGTAAAAACACAATCTCACACTTTTTCTACACATTGCTTTTACCTTTATAATGTAGCAGTGAAGTAAATCA
TTTTAGAACTTAATATCCAACTGATCATAGTACATATTGTAAATAAAATGTATTTTGATGACAGCTCAGTTGAATATGGATAATATGTGG
CATCACTTGCACACTTATTTTGTAGAAATGGGTAATTTGTGCCCGTAACACTGTTTCATATTAAATATGATAGCATTATCCCTGTATGAC
ACTGTGTTGTACAGTTAATGTATGATCCTTTTTAGATCGTTTAGGTTTTACACTAAGGAACATGATGACATGTTCTACATTTGTCTGTCT

>39565_39565_8_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000395762_RBBP6_chr16_24557483_ENST00000452655_length(amino acids)=93AA_BP=18
MVPWHLPMGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAVCKNTISHFFYTLL

--------------------------------------------------------------
>39565_39565_9_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000449195_RBBP6_chr16_24557483_ENST00000319715_length(transcript)=5943nt_BP=312nt
CCCCGCGCGGCGCGGGCCAGGGAAGGGCCACCCAGGGGTCCCCCACTTCCCGCTTGGGCGCCCGGACGGCGAATGGAGCAGGGGCGCGCA
GATAATTAAAGATTTACACACAGCTGGAAGAAATCATAGAGAAGCCGGGCGTGGTGGCTCATGCCTATAATCCCAGCACTTTTGGAGGCT
GAGGCGGGCAGATCACTTGAGATCAGGAGTTCGAGACCAGCCTGGTGCCTTGGCATCTCCCAATGGGGTGGCTTTGCTCTGGGCTCCTGT
TCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCTCTGAATATACTGATGATAATGCTCTGATTCCTAAGAATTCTTCTGTAATTG
TTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCAAGACATATGTTATAAGTCGAACTGAACCAGCGATGGCAACTACAAAAGCAA
TTGATGACTCTTCCGCGTCTATTTCTCTGGCCCAGCTTACAAAGACTGCCAATCTGGCTGAAGCCAATGCTTCTGAAGAAGATAAAATTA
AAGCAATGATGTCGCAATCTGGCCATGAATACGACCCAATCAATTACATGAAGAAACCTCTAGGTCCACCACCTCCATCTTACACGTGTT
TCCGTTGTGGTAAACCTGGACATTATATTAAGAATTGCCCAACAAATGGGGATAAAAACTTTGAATCTGGTCCTAGGATTAAAAAGAGCA
CTGGAATTCCCAGAAGTTTCATGATGGAAGTGAAAGATCCTAATATGAAAGGTGCAATGCTTACCAACACTGGAAAATATGCAATACCAA
CTATAGATGCAGAAGCATATGCAATTGGGAAGAAAGAGAAACCTCCCTTCTTACCAGAGGAGCCATCTTCTTCCTCAGAAGAAGATGATC
CTATCCCAGATGAATTGTTGTGTCTCATCTGCAAGGATATTATGACTGATGCTGTTGTGATTCCCTGCTGTGGAAACAGTTACTGTGATG
AATGTATAAGAACAGCACTCCTGGAATCAGATGAGCACACATGTCCGACGTGTCATCAAAATGATGTTTCTCCTGATGCTTTAATTGCCA
ATAAATTTTTACGACAGGCTGTAAATAACTTCAAAAATGAAACTGGCTATACAAAAAGACTACGAAAACAGTTACCTCCTCCACCACCCC
CAATACCACCTCCGAGACCACTGATTCAGAGGAACCTACAACCTCTGATGAGATCTCCGATATCAAGACAACAAGATCCTCTTATGATTC
CAGTGACATCTTCATCAACTCACCCAGCTCCGTCTATATCTTCATTAACTTCTAATCAGTCTTCCTTGGCCCCTCCTGTGTCTGGAAATC
CGTCTTCTGCTCCAGCTCCTGTACCTGATATAACTGCAACAGTATCCATATCAGTTCATTCAGAAAAATCAGATGGACCTTTTCGGGATT
CTGATAATAAAATATTGCCAGCTGCAGCTCTTGCATCAGAGCACTCAAAGGGAACCTCCTCAATTGCAATTACCGCTCTTATGGAAGAGA
AGGGTTACCAGGTGCCTGTTCTTGGAACCCCATCTTTGCTTGGACAGTCATTATTGCATGGACAGTTGATCCCCACAACTGGTCCAGTAA
GAATAAATACTGCTCGTCCAGGTGGTGGTCGACCAGGCTGGGAACATTCCAACAAACTTGGCTATCTGGTTTCTCCACCACAACAAATTA
GAAGAGGGGAGAGGAGCTGCTACAGAAGTATAAACCGTGGGCGACACCACAGCGAAAGATCACAGAGGACTCAAGGCCCGTCACTACCAG
CAACTCCAGTCTTTGTACCTGTTCCACCACCTCCTTTGTATCCGCCTCCTCCCCATACACTTCCTCTCCCTCCGGGTGTTCCTCCTCCAC
AGTTTTCTCCTCAGTTTCCTCCTGGCCAGCCACCACCCGCTGGGTATAGTGTCCCTCCTCCAGGGTTTCCTCCAGCTCCTGCCAATTTAT
CAACACCTTGGGTATCATCAGGAGTGCAGACAGCTCATTCAAATACCATCCCAACAACACAAGCACCACCTTTGTCCAGGGAAGAATTCT
ATAGAGAGCAGCGACGACTAAAAGAAGAGGAAAAGAAAAAGTCCAAGCTAGATGAGTTTACAAATGATTTTGCTAAGGAATTGATGGAAT
ACAAAAAGATTCAAAAGGAGCGTAGGCGCTCATTTTCCAGGTCTAAATCTCCCTATAGTGGTTCTTCGTATTCAAGAAGTTCATATACTT
ATTCTAAATCAAGATCTGGTTCAACACGTTCACGCTCTTATTCTCGATCATTCAGCCGCTCACATTCTCGTTCCTATTCACGGTCACCTC
CATACCCCAGAAGAGGCAGAGGCAAGAGCCGCAATTACCGTTCACGGTCTAGATCTCATGGATATCATCGATCTAGGTCAAGGTCACCCC
CTTACAGACGCTATCATTCACGATCAAGATCTCCTCAAGCGTTTAGGGGACAGTCTCCTAATAAACGTAATGTACCTCAAGGGGAAACAG
AACGTGAATATTTTAATAGATACAGAGAAGTTCCACCACCATATGACATGAAAGCATATTATGGGAGAAGTGTTGACTTTAGAGACCCAT
TTGAAAAAGAACGCTACCGAGAATGGGAGAGAAAATATAGAGAGTGGTATGAAAAATATTATAAAGGTTATGCTGCTGGAGCACAGCCTA
GACCCTCAGCAAATAGAGAGAACTTTTCTCCAGAGAGATTTTTGCCACTTAACATCAGGAATTCTCCCTTCACAAGAGGCCGCAGAGAAG
ACTATGTTGGTGGGCAAAGTCATAGAAGTCGAAACATAGGTAGCAACTATCCAGAAAAGCTTTCAGCAAGAGATGGTCACAATCAGAAGG
ATAATACAAAGTCAAAAGAGAAGGAGAGTGAAAACGCTCCAGGAGATGGTAAAGGAAATAAGCATAAGAAACACAGAAAAAGAAGAAAAG
GGGAGGAAAGTGAGGGTTTTCTGAACCCAGAGTTATTAGAGACTTCTAGGAAATCAAGAGAACCTACAGGTGTTGAAGAAAATAAAACAG
ACTCATTGTTTGTTCTCCCAAGTAGAGATGATGCCACACCTGTTAGAGATGAACCAATGGATGCAGAATCAATCACTTTTAAATCAGTGT
CTGAAAAAGACAAGAGAGAAAGGGATAAACCAAAAGCAAAGGGTGATAAAACCAAACGGAAGAATGATGGATCTGCTGTGTCCAAAAAAG
AAAATATTGTAAAACCTGCTAAAGGACCCCAAGAAAAAGTAGATGGAGAACGTGAGAGATCTCCTCGATCTGAACCTCCAATTAAAAAAG
CCAAAGAGGAGACTCCGAAGACTGACAATACTAAATCATCATCTTCCTCTCAGAAGGATGAAAAAATCACTGGAACCCCCAGAAAAGCTC
ACTCTAAATCAGCAAAAGAACACCAAGAAACAAAACCAGTCAAAGAGGAAAAAGTGAAGAAGGACTATTCCAAAGATGTCAAATCAGAAA
AGCTAACAACTAAGGAAGAAAAGGCCAAGAAGCCTAATGAGAAAAACAAACCACTTGATAATAAGGGAGAAAAAAGAAAAAGAAAAACTG
AAGAAAAAGGCGTAGATAAAGATTTTGAGTCTTCTTCAATGAAAATCTCGAAACTAGAAGTGACTGAAATAGTGAAACCATCACCAAAGC
GCAAAATGGAACCTGATACTGAAAAAATGGATAGGACCCCTGAAAAGGACAAAATTTCTTTAAGTGCGCCAGCCAAAAAAATCAAACTCA
ACAGAGAAACTGGGAAGAAAATTGGAAGTACAGAAAATATATCAAACACAAAAGAACCCTCTGAAAAATTGGAGTCAACATCTAGCAAAG
TTAAACAAGAAAAAGTCAAAGGAAAGGTCAGACGAAAAGTGACTGGAACTGAAGGATCCAGCTCAACTCTGGTGGATTACACCAGTACGA
GCTCAACTGGAGGCAGTCCTGTGCGGAAATCTGAAGAAAAAACAGATACAAAGCGAACTGTGATTAAAACGATGGAAGAATATAATAATG
ACAATACCGCGCCAGCTGAAGATGTTATCATTATGATTCAGGTTCCTCAATCCAAATGGGATAAAGATGACTTTGAATCTGAAGAAGAAG
ATGTTAAATCCACACAGCCTATATCAAGTGTAGGAAAACCTGCTAGTGTTATAAAAAATGTTAGTACAAAGCCATCAAATATAGTCAAGT
ATCCTGAGAAAGAAAGTGAGCCATCCGAGAAAATTCAGAAATTCACCAAGGACGTGAGCCATGAAATCATACAACATGAGGTTAAAAGTT
CAAAAAACTCTGCATCTAGTGAAAAAGGGAAAACCAAAGATCGAGATTATTCAGTGTTGGAAAAGGAGAACCCTGAAAAGAGGAAGAACA
GCACTCAGCCAGAGAAAGAGAGTAATTTGGACCGTCTGAATGAACAAGGAAATTTTAAAAGTCTGTCTCAATCTTCCAAAGAGGCTAGAA
CGTCAGATAAACATGATTCCACTCGTGCTTCCTCAAATAAAGACTTCACTCCCAATAGAGACAAAAAAACTGACTATGACACCAGAGAGT
ATTCAAGTTCCAAACGTAGAGATGAAAAGAATGAATTAACAAGACGAAAAGACTCTCCTTCTCGGAATAAAGATTCTGCATCTGGACAGA
AAAATAAACCAAGGGAAGAGAGAGATTTGCCTAAAAAAGGAACAGGAGATTCCAAAAAAAGTAATTCTAGTCCCTCAAGAGACAGAAAAC
CTCATGATCACAAAGCCACTTATGATACTAAACGGCCAAATGAAGAGACAAAATCTGTAGATAAAAATCCTTGTAAGGATCGTGAGAAGC
ATGTATTAGAAGCAAGGAACAATAAAGAGTCAAGTGGCAATAAACTACTTTATATACTTAACCCACCAGAGACACAGGTTGAAAAAGAGC
AAATTACTGGGCAAATTGACAAGAGTACTGTCAAGCCTAAACCCCAGTTAAGTCATTCCTCTAGACTTTCCTCTGACTTAACTAGAGAAA
CTGATGAAGCTGCTTTTGAACCAGACTATAATGAAAGTGACAGTGAAAGTAATGTTTCTGTAAAAGAAGAGGAATCTTCAGGAAACATTT
CTAAGGACCTGAAAGATAAAATAGTGGAGAAAGCAAAAGAGAGCCTGGACACAGCAGCAGTTGTCCAGGTGGGCATAAGCAGGAATCAGA
GCCACAGCAGCCCCAGCGTCAGCCCCAGCAGAAGCCACAGTCCTTCTGGAAGCCAGACCCGAAGCCACAGTAGCAGTGCCAGCTCAGCAG
AAAGTCAGGACAGCAAGAAGAAGAAGAAAAAGAAGGAAAAGAAAAAACACAAGAAACATAAAAAGCATAAGAAGCATAAGAAACATGCAG
GCACTGAAGTGGAATTGGAAAAAAGCCAAAAACACAAACACAAGAAAAAGAAGTCAAAGAAGAACAAAGATAAAGAGAAGGAGAAGGAGA
AAGATGACCAAAAAGTGAAATCTGTCACTGTGTAAAAAGACAGATTTTTTAAATTGACTTAATTACTAAGTCATCTGTATTAAATTTTGT
TATAATGTAAAGAGATTCAAGCCTTGTAAATAATGACATGGAAGACCCTGTGCTGCACTTAAAATATTGCTGCTTGATTATTTGATTTTT
ACATCAGAGCTTTATAACACGAACTTTTGTACAGAATTGTGAGTTGTGACCATGTAACATGAGAGGTTTTGCTAGGGCCTATTATTTTTA
ACCACCATTAATTAGTTGGGGTGGAGTTTACTGTAATGTGAAATTTTCACATTTGAATTTTTTAATTGCCTGGCAAAAGCTGATATAAGT
TCTAAAATATCAGCAGAATGATTTGCTGAATTCATTACAACCCTGTTATGTCACTTTTTGATTACAATAAAAGTTTTCAGTAAACTTTTC

>39565_39565_9_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000449195_RBBP6_chr16_24557483_ENST00000319715_length(amino acids)=1767AA_BP=1698
MVPWHLPMGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLT
KTANLAEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDP
NMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHT
CPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSIS
SLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLL
GQSLLHGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLY
PPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKK
SKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYR
SRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYR
EWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAP
GDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAK
GDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPV
KEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTP
EKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEK
TDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQK
FTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNK
DFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPN
EETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESD
SESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEK

--------------------------------------------------------------
>39565_39565_10_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000449195_RBBP6_chr16_24557483_ENST00000348022_length(transcript)=5841nt_BP=312nt
CCCCGCGCGGCGCGGGCCAGGGAAGGGCCACCCAGGGGTCCCCCACTTCCCGCTTGGGCGCCCGGACGGCGAATGGAGCAGGGGCGCGCA
GATAATTAAAGATTTACACACAGCTGGAAGAAATCATAGAGAAGCCGGGCGTGGTGGCTCATGCCTATAATCCCAGCACTTTTGGAGGCT
GAGGCGGGCAGATCACTTGAGATCAGGAGTTCGAGACCAGCCTGGTGCCTTGGCATCTCCCAATGGGGTGGCTTTGCTCTGGGCTCCTGT
TCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCTCTGAATATACTGATGATAATGCTCTGATTCCTAAGAATTCTTCTGTAATTG
TTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCAAGACATATGTTATAAGTCGAACTGAACCAGCGATGGCAACTACAAAAGCAA
TTGATGACTCTTCCGCGTCTATTTCTCTGGCCCAGCTTACAAAGACTGCCAATCTGGCTGAAGCCAATGCTTCTGAAGAAGATAAAATTA
AAGCAATGATGTCGCAATCTGGCCATGAATACGACCCAATCAATTACATGAAGAAACCTCTAGGTCCACCACCTCCATCTTACACGTGTT
TCCGTTGTGGTAAACCTGGACATTATATTAAGAATTGCCCAACAAATGGGGATAAAAACTTTGAATCTGGTCCTAGGATTAAAAAGAGCA
CTGGAATTCCCAGAAGTTTCATGATGGAAGTGAAAGATCCTAATATGAAAGGTGCAATGCTTACCAACACTGGAAAATATGCAATACCAA
CTATAGATGCAGAAGCATATGCAATTGGGAAGAAAGAGAAACCTCCCTTCTTACCAGAGGAGCCATCTTCTTCCTCAGAAGAAGATGATC
CTATCCCAGATGAATTGTTGTGTCTCATCTGCAAGGATATTATGACTGATGCTGTTGTGATTCCCTGCTGTGGAAACAGTTACTGTGATG
AATGTATAAGAACAGCACTCCTGGAATCAGATGAGCACACATGTCCGACGTGTCATCAAAATGATGTTTCTCCTGATGCTTTAATTGCCA
ATAAATTTTTACGACAGGCTGTAAATAACTTCAAAAATGAAACTGGCTATACAAAAAGACTACGAAAACAGTTACCTCCTCCACCACCCC
CAATACCACCTCCGAGACCACTGATTCAGAGGAACCTACAACCTCTGATGAGATCTCCGATATCAAGACAACAAGATCCTCTTATGATTC
CAGTGACATCTTCATCAACTCACCCAGCTCCGTCTATATCTTCATTAACTTCTAATCAGTCTTCCTTGGCCCCTCCTGTGTCTGGAAATC
CGTCTTCTGCTCCAGCTCCTGTACCTGATATAACTGCAACAGTATCCATATCAGTTCATTCAGAAAAATCAGATGGACCTTTTCGGGATT
CTGATAATAAAATATTGCCAGCTGCAGCTCTTGCATCAGAGCACTCAAAGGGAACCTCCTCAATTGCAATTACCGCTCTTATGGAAGAGA
AGGGTTACCAGGTGCCTGTTCTTGGAACCCCATCTTTGCTTGGACAGTCATTATTGCATGGACAGTTGATCCCCACAACTGGTCCAGTAA
GAATAAATACTGCTCGTCCAGGTGGTGGTCGACCAGGCTGGGAACATTCCAACAAACTTGGCTATCTGGTTTCTCCACCACAACAAATTA
GAAGAGGGGAGAGGAGCTGCTACAGAAGTATAAACCGTGGGCGACACCACAGCGAAAGATCACAGAGGACTCAAGGCCCGTCACTACCAG
CAACTCCAGTCTTTGTACCTGTTCCACCACCTCCTTTGTATCCGCCTCCTCCCCATACACTTCCTCTCCCTCCGGGTGTTCCTCCTCCAC
AGTTTTCTCCTCAGTTTCCTCCTGGCCAGCCACCACCCGCTGGGTATAGTGTCCCTCCTCCAGGGTTTCCTCCAGCTCCTGCCAATTTAT
CAACACCTTGGGTATCATCAGGAGTGCAGACAGCTCATTCAAATACCATCCCAACAACACAAGCACCACCTTTGTCCAGGGAAGAATTCT
ATAGAGAGCAGCGACGACTAAAAGAAGAGTCTAAATCTCCCTATAGTGGTTCTTCGTATTCAAGAAGTTCATATACTTATTCTAAATCAA
GATCTGGTTCAACACGTTCACGCTCTTATTCTCGATCATTCAGCCGCTCACATTCTCGTTCCTATTCACGGTCACCTCCATACCCCAGAA
GAGGCAGAGGCAAGAGCCGCAATTACCGTTCACGGTCTAGATCTCATGGATATCATCGATCTAGGTCAAGGTCACCCCCTTACAGACGCT
ATCATTCACGATCAAGATCTCCTCAAGCGTTTAGGGGACAGTCTCCTAATAAACGTAATGTACCTCAAGGGGAAACAGAACGTGAATATT
TTAATAGATACAGAGAAGTTCCACCACCATATGACATGAAAGCATATTATGGGAGAAGTGTTGACTTTAGAGACCCATTTGAAAAAGAAC
GCTACCGAGAATGGGAGAGAAAATATAGAGAGTGGTATGAAAAATATTATAAAGGTTATGCTGCTGGAGCACAGCCTAGACCCTCAGCAA
ATAGAGAGAACTTTTCTCCAGAGAGATTTTTGCCACTTAACATCAGGAATTCTCCCTTCACAAGAGGCCGCAGAGAAGACTATGTTGGTG
GGCAAAGTCATAGAAGTCGAAACATAGGTAGCAACTATCCAGAAAAGCTTTCAGCAAGAGATGGTCACAATCAGAAGGATAATACAAAGT
CAAAAGAGAAGGAGAGTGAAAACGCTCCAGGAGATGGTAAAGGAAATAAGCATAAGAAACACAGAAAAAGAAGAAAAGGGGAGGAAAGTG
AGGGTTTTCTGAACCCAGAGTTATTAGAGACTTCTAGGAAATCAAGAGAACCTACAGGTGTTGAAGAAAATAAAACAGACTCATTGTTTG
TTCTCCCAAGTAGAGATGATGCCACACCTGTTAGAGATGAACCAATGGATGCAGAATCAATCACTTTTAAATCAGTGTCTGAAAAAGACA
AGAGAGAAAGGGATAAACCAAAAGCAAAGGGTGATAAAACCAAACGGAAGAATGATGGATCTGCTGTGTCCAAAAAAGAAAATATTGTAA
AACCTGCTAAAGGACCCCAAGAAAAAGTAGATGGAGAACGTGAGAGATCTCCTCGATCTGAACCTCCAATTAAAAAAGCCAAAGAGGAGA
CTCCGAAGACTGACAATACTAAATCATCATCTTCCTCTCAGAAGGATGAAAAAATCACTGGAACCCCCAGAAAAGCTCACTCTAAATCAG
CAAAAGAACACCAAGAAACAAAACCAGTCAAAGAGGAAAAAGTGAAGAAGGACTATTCCAAAGATGTCAAATCAGAAAAGCTAACAACTA
AGGAAGAAAAGGCCAAGAAGCCTAATGAGAAAAACAAACCACTTGATAATAAGGGAGAAAAAAGAAAAAGAAAAACTGAAGAAAAAGGCG
TAGATAAAGATTTTGAGTCTTCTTCAATGAAAATCTCGAAACTAGAAGTGACTGAAATAGTGAAACCATCACCAAAGCGCAAAATGGAAC
CTGATACTGAAAAAATGGATAGGACCCCTGAAAAGGACAAAATTTCTTTAAGTGCGCCAGCCAAAAAAATCAAACTCAACAGAGAAACTG
GGAAGAAAATTGGAAGTACAGAAAATATATCAAACACAAAAGAACCCTCTGAAAAATTGGAGTCAACATCTAGCAAAGTTAAACAAGAAA
AAGTCAAAGGAAAGGTCAGACGAAAAGTGACTGGAACTGAAGGATCCAGCTCAACTCTGGTGGATTACACCAGTACGAGCTCAACTGGAG
GCAGTCCTGTGCGGAAATCTGAAGAAAAAACAGATACAAAGCGAACTGTGATTAAAACGATGGAAGAATATAATAATGACAATACCGCGC
CAGCTGAAGATGTTATCATTATGATTCAGGTTCCTCAATCCAAATGGGATAAAGATGACTTTGAATCTGAAGAAGAAGATGTTAAATCCA
CACAGCCTATATCAAGTGTAGGAAAACCTGCTAGTGTTATAAAAAATGTTAGTACAAAGCCATCAAATATAGTCAAGTATCCTGAGAAAG
AAAGTGAGCCATCCGAGAAAATTCAGAAATTCACCAAGGACGTGAGCCATGAAATCATACAACATGAGGTTAAAAGTTCAAAAAACTCTG
CATCTAGTGAAAAAGGGAAAACCAAAGATCGAGATTATTCAGTGTTGGAAAAGGAGAACCCTGAAAAGAGGAAGAACAGCACTCAGCCAG
AGAAAGAGAGTAATTTGGACCGTCTGAATGAACAAGGAAATTTTAAAAGTCTGTCTCAATCTTCCAAAGAGGCTAGAACGTCAGATAAAC
ATGATTCCACTCGTGCTTCCTCAAATAAAGACTTCACTCCCAATAGAGACAAAAAAACTGACTATGACACCAGAGAGTATTCAAGTTCCA
AACGTAGAGATGAAAAGAATGAATTAACAAGACGAAAAGACTCTCCTTCTCGGAATAAAGATTCTGCATCTGGACAGAAAAATAAACCAA
GGGAAGAGAGAGATTTGCCTAAAAAAGGAACAGGAGATTCCAAAAAAAGTAATTCTAGTCCCTCAAGAGACAGAAAACCTCATGATCACA
AAGCCACTTATGATACTAAACGGCCAAATGAAGAGACAAAATCTGTAGATAAAAATCCTTGTAAGGATCGTGAGAAGCATGTATTAGAAG
CAAGGAACAATAAAGAGTCAAGTGGCAATAAACTACTTTATATACTTAACCCACCAGAGACACAGGTTGAAAAAGAGCAAATTACTGGGC
AAATTGACAAGAGTACTGTCAAGCCTAAACCCCAGTTAAGTCATTCCTCTAGACTTTCCTCTGACTTAACTAGAGAAACTGATGAAGCTG
CTTTTGAACCAGACTATAATGAAAGTGACAGTGAAAGTAATGTTTCTGTAAAAGAAGAGGAATCTTCAGGAAACATTTCTAAGGACCTGA
AAGATAAAATAGTGGAGAAAGCAAAAGAGAGCCTGGACACAGCAGCAGTTGTCCAGGTGGGCATAAGCAGGAATCAGAGCCACAGCAGCC
CCAGCGTCAGCCCCAGCAGAAGCCACAGTCCTTCTGGAAGCCAGACCCGAAGCCACAGTAGCAGTGCCAGCTCAGCAGAAAGTCAGGACA
GCAAGAAGAAGAAGAAAAAGAAGGAAAAGAAAAAACACAAGAAACATAAAAAGCATAAGAAGCATAAGAAACATGCAGGCACTGAAGTGG
AATTGGAAAAAAGCCAAAAACACAAACACAAGAAAAAGAAGTCAAAGAAGAACAAAGATAAAGAGAAGGAGAAGGAGAAAGATGACCAAA
AAGTGAAATCTGTCACTGTGTAAAAAGACAGATTTTTTAAATTGACTTAATTACTAAGTCATCTGTATTAAATTTTGTTATAATGTAAAG
AGATTCAAGCCTTGTAAATAATGACATGGAAGACCCTGTGCTGCACTTAAAATATTGCTGCTTGATTATTTGATTTTTACATCAGAGCTT
TATAACACGAACTTTTGTACAGAATTGTGAGTTGTGACCATGTAACATGAGAGGTTTTGCTAGGGCCTATTATTTTTAACCACCATTAAT
TAGTTGGGGTGGAGTTTACTGTAATGTGAAATTTTCACATTTGAATTTTTTAATTGCCTGGCAAAAGCTGATATAAGTTCTAAAATATCA

>39565_39565_10_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000449195_RBBP6_chr16_24557483_ENST00000348022_length(amino acids)=1733AA_BP=1664
MVPWHLPMGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLT
KTANLAEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDP
NMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHT
CPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSIS
SLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLL
GQSLLHGQLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLY
PPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSP
YSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQ
SPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLN
IRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRK
SREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGER
ERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKP
LDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTK
EPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQS
KWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYS
VLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKD
SPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLY
ILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDT
AAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKK

--------------------------------------------------------------
>39565_39565_11_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000449195_RBBP6_chr16_24557483_ENST00000381039_length(transcript)=3423nt_BP=312nt
CCCCGCGCGGCGCGGGCCAGGGAAGGGCCACCCAGGGGTCCCCCACTTCCCGCTTGGGCGCCCGGACGGCGAATGGAGCAGGGGCGCGCA
GATAATTAAAGATTTACACACAGCTGGAAGAAATCATAGAGAAGCCGGGCGTGGTGGCTCATGCCTATAATCCCAGCACTTTTGGAGGCT
GAGGCGGGCAGATCACTTGAGATCAGGAGTTCGAGACCAGCCTGGTGCCTTGGCATCTCCCAATGGGGTGGCTTTGCTCTGGGCTCCTGT
TCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCTCTGAATATACTGATGATAATGCTCTGATTCCTAAGAATTCTTCTGTAATTG
TTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCAAGACATATGTTATAAGTCGAACTGAACCAGCGATGGCAACTACAAAAGCAA
TTGATGACTCTTCCGCGTCTATTTCTCTGGCCCAGCTTACAAAGACTGCCAATCTGGCTGAAGCCAATGCTTCTGAAGAAGATAAAATTA
AAGCAATGATGTCGCAATCTGGCCATGAATACGACCCAATCAATTACATGAAGAAACCTCTAGGTCCACCACCTCCATCTTACACGTGTT
TCCGTTGTGGTAAACCTGGACATTATATTAAGAATTGCCCAACAAATGGGGATAAAAACTTTGAATCTGGTCCTAGGATTAAAAAGAGCA
CTGGAATTCCCAGAAGTTTCATGATGGAAGTGAAAGATCCTAATATGAAAGGTGCAATGCTTACCAACACTGGAAAATATGCAATACCAA
CTATAGATGCAGAAGCATATGCAATTGGGAAGAAAGAGAAACCTCCCTTCTTACCAGAGGAGCCATCTTCTTCCTCAGAAGAAGATGATC
CTATCCCAGATGAATTGTTGTGTCTCATCTGCAAGGATATTATGACTGATGCTGTTGTGATTCCCTGCTGTGGAAACAGTTACTGTGATG
AATGTATAAGAACAGCACTCCTGGAATCAGATGAGCACACATGTCCGACGTGTCATCAAAATGATGTTTCTCCTGATGCTTTAATTGCCA
ATAAATTTTTACGACAGGCTGTAAATAACTTCAAAAATGAAACTGGCTATACAAAAAGACTACGAAAACAGTTACCTCCTCCACCACCCC
CAATACCACCTCCGAGACCACTGATTCAGAGGAACCTACAACCTCTGATGAGATCTCCGATATCAAGACAACAAGATCCTCTTATGATTC
CAGTGACATCTTCATCAACTCACCCAGCTCCGTCTATATCTTCATTAACTTCTAATCAGTCTTCCTTGGCCCCTCCTGTGTCTGGAAATC
CGTCTTCTGCTCCAGCTCCTGTACCTGATATAACTGCAACAGTATCCATATCAGTTCATTCAGAAAAATCAGATGGACCTTTTCGTACGA
GCTCAACTGGAGGCAGTCCTGTGCGGAAATCTGAAGAAAAAACAGATACAAAGCGAACTGTGATTAAAACGATGGAAGAATATAATAATG
ACAATACCGCGCCAGCTGAAGATGTTATCATTATGATTCAGGTTCCTCAATCCAAATGGGATAAAGATGACTTTGAATCTGAAGAAGAAG
ATGTTAAATCCACACAGCCTATATCAAGTGTAGGAAAACCTGCTAGTGTTATAAAAAATGTTAGTACAAAGCCATCAAATATAGTCAAGT
ATCCTGAGAAAGAAAGTGAGCCATCCGAGAAAATTCAGAAATTCACCAAGGACGTGAGCCATGAAATCATACAACATGAGGTTAAAAGTT
CAAAAAACTCTGCATCTAGTGAAAAAGGGAAAACCAAAGATCGAGATTATTCAGTGTTGGAAAAGGAGAACCCTGAAAAGAGGAAGAACA
GCACTCAGCCAGAGAAAGAGAGTAATTTGGACCGTCTGAATGAACAAGGAAATTTTAAAAGTCTGTCTCAATCTTCCAAAGAGGCTAGAA
CGTCAGATAAACATGATTCCACTCGTGCTTCCTCAAATAAAGACTTCACTCCCAATAGAGACAAAAAAACTGACTATGACACCAGAGAGT
ATTCAAGTTCCAAACGTAGAGATGAAAAGAATGAATTAACAAGACGAAAAGACTCTCCTTCTCGGAATAAAGATTCTGCATCTGGACAGA
AAAATAAACCAAGGGAAGAGAGAGATTTGCCTAAAAAAGGAACAGGAGATTCCAAAAAAAGTAATTCTAGTCCCTCAAGAGACAGAAAAC
CTCATGATCACAAAGCCACTTATGATACTAAACGGCCAAATGAAGAGACAAAATCTGTAGATAAAAATCCTTGTAAGGATCGTGAGAAGC
ATGTATTAGAAGCAAGGAACAATAAAGAGTCAAGTGGCAATAAACTACTTTATATACTTAACCCACCAGAGACACAGGTTGAAAAAGAGC
AAATTACTGGGCAAATTGACAAGAGTACTGTCAAGCCTAAACCCCAGTTAAGTCATTCCTCTAGACTTTCCTCTGACTTAACTAGAGAAA
CTGATGAAGCTGCTTTTGAACCAGACTATAATGAAAGTGACAGTGAAAGTAATGTTTCTGTAAAAGAAGAGGAATCTTCAGGAAACATTT
CTAAGGACCTGAAAGATAAAATAGTGGAGAAAGCAAAAGAGAGCCTGGACACAGCAGCAGTTGTCCAGGTGGGCATAAGCAGGAATCAGA
GCCACAGCAGCCCCAGCGTCAGCCCCAGCAGAAGCCACAGTCCTTCTGGAAGCCAGACCCGAAGCCACAGTAGCAGTGCCAGCTCAGCAG
AAAGTCAGGACAGCAAGAAGAAGAAGAAAAAGAAGGAAAAGAAAAAACACAAGAAACATAAAAAGCATAAGAAGCATAAGAAACATGCAG
GCACTGAAGTGGAATTGGAAAAAAGCCAAAAACACAAACACAAGAAAAAGAAGTCAAAGAAGAACAAAGATAAAGAGAAGGAGAAGGAGA
AAGATGACCAAAAAGTGAAATCTGTCACTGTGTAAAAAGACAGATTTTTTAAATTGACTTAATTACTAAGTCATCTGTATTAAATTTTGT
TATAATGTAAAGAGATTCAAGCCTTGTAAATAATGACATGGAAGACCCTGTGCTGCACTTAAAATATTGCTGCTTGATTATTTGATTTTT
ACATCAGAGCTTTATAACACGAACTTTTGTACAGAATTGTGAGTTGTGACCATGTAACATGAGAGGTTTTGCTAGGGCCTATTATTTTTA
ACCACCATTAATTAGTTGGGGTGGAGTTTACTGTAATGTGAAATTTTCACATTTGAATTTTTTAATTGCCTGGCAAAAGCTGATATAAGT
TCTAAAATATCAGCAGAATGATTTGCTGAATTCATTACAACCCTGTTATGTCACTTTTTGATTACAATAAAAGTTTTCAGTAAACTTTTC

>39565_39565_11_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000449195_RBBP6_chr16_24557483_ENST00000381039_length(amino acids)=927AA_BP=858
MVPWHLPMGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLT
KTANLAEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDP
NMKGAMLTNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHT
CPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSIS
SLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQ
VPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKD
RDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELT
RRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGN
KLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKE
SLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKH

--------------------------------------------------------------
>39565_39565_12_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000449195_RBBP6_chr16_24557483_ENST00000452655_length(transcript)=869nt_BP=312nt
CCCCGCGCGGCGCGGGCCAGGGAAGGGCCACCCAGGGGTCCCCCACTTCCCGCTTGGGCGCCCGGACGGCGAATGGAGCAGGGGCGCGCA
GATAATTAAAGATTTACACACAGCTGGAAGAAATCATAGAGAAGCCGGGCGTGGTGGCTCATGCCTATAATCCCAGCACTTTTGGAGGCT
GAGGCGGGCAGATCACTTGAGATCAGGAGTTCGAGACCAGCCTGGTGCCTTGGCATCTCCCAATGGGGTGGCTTTGCTCTGGGCTCCTGT
TCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCTCTGAATATACTGATGATAATGCTCTGATTCCTAAGAATTCTTCTGTAATTG
TTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCAAGACATATGTTATAAGTCGAACTGAACCAGCGATGGCAACTACAAAAGCAG
TATGTAAAAACACAATCTCACACTTTTTCTACACATTGCTTTTACCTTTATAATGTAGCAGTGAAGTAAATCATTTTAGAACTTAATATC
CAACTGATCATAGTACATATTGTAAATAAAATGTATTTTGATGACAGCTCAGTTGAATATGGATAATATGTGGCATCACTTGCACACTTA
TTTTGTAGAAATGGGTAATTTGTGCCCGTAACACTGTTTCATATTAAATATGATAGCATTATCCCTGTATGACACTGTGTTGTACAGTTA
ATGTATGATCCTTTTTAGATCGTTTAGGTTTTACACTAAGGAACATGATGACATGTTCTACATTTGTCTGTCTATAGTTAGTATTTTGTA

>39565_39565_12_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000449195_RBBP6_chr16_24557483_ENST00000452655_length(amino acids)=93AA_BP=18
MVPWHLPMGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAVCKNTISHFFYTLL

--------------------------------------------------------------
>39565_39565_13_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000543915_RBBP6_chr16_24557483_ENST00000319715_length(transcript)=5814nt_BP=183nt
AAAGCCCCGCGCGGCGCGGGCCAGGGAAGGGCCACCCAGGGGTCCCCCACTTCCCGCTTGGGCGCCCGGACGGCGAATGGAGCAGGGGCG
CGCAGGTGCCTTGGCATCTCCCAATGGGGTGGCTTTGCTCTGGGCTCCTGTTCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCT
CTGAATATACTGATGATAATGCTCTGATTCCTAAGAATTCTTCTGTAATTGTTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCA
AGACATATGTTATAAGTCGAACTGAACCAGCGATGGCAACTACAAAAGCAATTGATGACTCTTCCGCGTCTATTTCTCTGGCCCAGCTTA
CAAAGACTGCCAATCTGGCTGAAGCCAATGCTTCTGAAGAAGATAAAATTAAAGCAATGATGTCGCAATCTGGCCATGAATACGACCCAA
TCAATTACATGAAGAAACCTCTAGGTCCACCACCTCCATCTTACACGTGTTTCCGTTGTGGTAAACCTGGACATTATATTAAGAATTGCC
CAACAAATGGGGATAAAAACTTTGAATCTGGTCCTAGGATTAAAAAGAGCACTGGAATTCCCAGAAGTTTCATGATGGAAGTGAAAGATC
CTAATATGAAAGGTGCAATGCTTACCAACACTGGAAAATATGCAATACCAACTATAGATGCAGAAGCATATGCAATTGGGAAGAAAGAGA
AACCTCCCTTCTTACCAGAGGAGCCATCTTCTTCCTCAGAAGAAGATGATCCTATCCCAGATGAATTGTTGTGTCTCATCTGCAAGGATA
TTATGACTGATGCTGTTGTGATTCCCTGCTGTGGAAACAGTTACTGTGATGAATGTATAAGAACAGCACTCCTGGAATCAGATGAGCACA
CATGTCCGACGTGTCATCAAAATGATGTTTCTCCTGATGCTTTAATTGCCAATAAATTTTTACGACAGGCTGTAAATAACTTCAAAAATG
AAACTGGCTATACAAAAAGACTACGAAAACAGTTACCTCCTCCACCACCCCCAATACCACCTCCGAGACCACTGATTCAGAGGAACCTAC
AACCTCTGATGAGATCTCCGATATCAAGACAACAAGATCCTCTTATGATTCCAGTGACATCTTCATCAACTCACCCAGCTCCGTCTATAT
CTTCATTAACTTCTAATCAGTCTTCCTTGGCCCCTCCTGTGTCTGGAAATCCGTCTTCTGCTCCAGCTCCTGTACCTGATATAACTGCAA
CAGTATCCATATCAGTTCATTCAGAAAAATCAGATGGACCTTTTCGGGATTCTGATAATAAAATATTGCCAGCTGCAGCTCTTGCATCAG
AGCACTCAAAGGGAACCTCCTCAATTGCAATTACCGCTCTTATGGAAGAGAAGGGTTACCAGGTGCCTGTTCTTGGAACCCCATCTTTGC
TTGGACAGTCATTATTGCATGGACAGTTGATCCCCACAACTGGTCCAGTAAGAATAAATACTGCTCGTCCAGGTGGTGGTCGACCAGGCT
GGGAACATTCCAACAAACTTGGCTATCTGGTTTCTCCACCACAACAAATTAGAAGAGGGGAGAGGAGCTGCTACAGAAGTATAAACCGTG
GGCGACACCACAGCGAAAGATCACAGAGGACTCAAGGCCCGTCACTACCAGCAACTCCAGTCTTTGTACCTGTTCCACCACCTCCTTTGT
ATCCGCCTCCTCCCCATACACTTCCTCTCCCTCCGGGTGTTCCTCCTCCACAGTTTTCTCCTCAGTTTCCTCCTGGCCAGCCACCACCCG
CTGGGTATAGTGTCCCTCCTCCAGGGTTTCCTCCAGCTCCTGCCAATTTATCAACACCTTGGGTATCATCAGGAGTGCAGACAGCTCATT
CAAATACCATCCCAACAACACAAGCACCACCTTTGTCCAGGGAAGAATTCTATAGAGAGCAGCGACGACTAAAAGAAGAGGAAAAGAAAA
AGTCCAAGCTAGATGAGTTTACAAATGATTTTGCTAAGGAATTGATGGAATACAAAAAGATTCAAAAGGAGCGTAGGCGCTCATTTTCCA
GGTCTAAATCTCCCTATAGTGGTTCTTCGTATTCAAGAAGTTCATATACTTATTCTAAATCAAGATCTGGTTCAACACGTTCACGCTCTT
ATTCTCGATCATTCAGCCGCTCACATTCTCGTTCCTATTCACGGTCACCTCCATACCCCAGAAGAGGCAGAGGCAAGAGCCGCAATTACC
GTTCACGGTCTAGATCTCATGGATATCATCGATCTAGGTCAAGGTCACCCCCTTACAGACGCTATCATTCACGATCAAGATCTCCTCAAG
CGTTTAGGGGACAGTCTCCTAATAAACGTAATGTACCTCAAGGGGAAACAGAACGTGAATATTTTAATAGATACAGAGAAGTTCCACCAC
CATATGACATGAAAGCATATTATGGGAGAAGTGTTGACTTTAGAGACCCATTTGAAAAAGAACGCTACCGAGAATGGGAGAGAAAATATA
GAGAGTGGTATGAAAAATATTATAAAGGTTATGCTGCTGGAGCACAGCCTAGACCCTCAGCAAATAGAGAGAACTTTTCTCCAGAGAGAT
TTTTGCCACTTAACATCAGGAATTCTCCCTTCACAAGAGGCCGCAGAGAAGACTATGTTGGTGGGCAAAGTCATAGAAGTCGAAACATAG
GTAGCAACTATCCAGAAAAGCTTTCAGCAAGAGATGGTCACAATCAGAAGGATAATACAAAGTCAAAAGAGAAGGAGAGTGAAAACGCTC
CAGGAGATGGTAAAGGAAATAAGCATAAGAAACACAGAAAAAGAAGAAAAGGGGAGGAAAGTGAGGGTTTTCTGAACCCAGAGTTATTAG
AGACTTCTAGGAAATCAAGAGAACCTACAGGTGTTGAAGAAAATAAAACAGACTCATTGTTTGTTCTCCCAAGTAGAGATGATGCCACAC
CTGTTAGAGATGAACCAATGGATGCAGAATCAATCACTTTTAAATCAGTGTCTGAAAAAGACAAGAGAGAAAGGGATAAACCAAAAGCAA
AGGGTGATAAAACCAAACGGAAGAATGATGGATCTGCTGTGTCCAAAAAAGAAAATATTGTAAAACCTGCTAAAGGACCCCAAGAAAAAG
TAGATGGAGAACGTGAGAGATCTCCTCGATCTGAACCTCCAATTAAAAAAGCCAAAGAGGAGACTCCGAAGACTGACAATACTAAATCAT
CATCTTCCTCTCAGAAGGATGAAAAAATCACTGGAACCCCCAGAAAAGCTCACTCTAAATCAGCAAAAGAACACCAAGAAACAAAACCAG
TCAAAGAGGAAAAAGTGAAGAAGGACTATTCCAAAGATGTCAAATCAGAAAAGCTAACAACTAAGGAAGAAAAGGCCAAGAAGCCTAATG
AGAAAAACAAACCACTTGATAATAAGGGAGAAAAAAGAAAAAGAAAAACTGAAGAAAAAGGCGTAGATAAAGATTTTGAGTCTTCTTCAA
TGAAAATCTCGAAACTAGAAGTGACTGAAATAGTGAAACCATCACCAAAGCGCAAAATGGAACCTGATACTGAAAAAATGGATAGGACCC
CTGAAAAGGACAAAATTTCTTTAAGTGCGCCAGCCAAAAAAATCAAACTCAACAGAGAAACTGGGAAGAAAATTGGAAGTACAGAAAATA
TATCAAACACAAAAGAACCCTCTGAAAAATTGGAGTCAACATCTAGCAAAGTTAAACAAGAAAAAGTCAAAGGAAAGGTCAGACGAAAAG
TGACTGGAACTGAAGGATCCAGCTCAACTCTGGTGGATTACACCAGTACGAGCTCAACTGGAGGCAGTCCTGTGCGGAAATCTGAAGAAA
AAACAGATACAAAGCGAACTGTGATTAAAACGATGGAAGAATATAATAATGACAATACCGCGCCAGCTGAAGATGTTATCATTATGATTC
AGGTTCCTCAATCCAAATGGGATAAAGATGACTTTGAATCTGAAGAAGAAGATGTTAAATCCACACAGCCTATATCAAGTGTAGGAAAAC
CTGCTAGTGTTATAAAAAATGTTAGTACAAAGCCATCAAATATAGTCAAGTATCCTGAGAAAGAAAGTGAGCCATCCGAGAAAATTCAGA
AATTCACCAAGGACGTGAGCCATGAAATCATACAACATGAGGTTAAAAGTTCAAAAAACTCTGCATCTAGTGAAAAAGGGAAAACCAAAG
ATCGAGATTATTCAGTGTTGGAAAAGGAGAACCCTGAAAAGAGGAAGAACAGCACTCAGCCAGAGAAAGAGAGTAATTTGGACCGTCTGA
ATGAACAAGGAAATTTTAAAAGTCTGTCTCAATCTTCCAAAGAGGCTAGAACGTCAGATAAACATGATTCCACTCGTGCTTCCTCAAATA
AAGACTTCACTCCCAATAGAGACAAAAAAACTGACTATGACACCAGAGAGTATTCAAGTTCCAAACGTAGAGATGAAAAGAATGAATTAA
CAAGACGAAAAGACTCTCCTTCTCGGAATAAAGATTCTGCATCTGGACAGAAAAATAAACCAAGGGAAGAGAGAGATTTGCCTAAAAAAG
GAACAGGAGATTCCAAAAAAAGTAATTCTAGTCCCTCAAGAGACAGAAAACCTCATGATCACAAAGCCACTTATGATACTAAACGGCCAA
ATGAAGAGACAAAATCTGTAGATAAAAATCCTTGTAAGGATCGTGAGAAGCATGTATTAGAAGCAAGGAACAATAAAGAGTCAAGTGGCA
ATAAACTACTTTATATACTTAACCCACCAGAGACACAGGTTGAAAAAGAGCAAATTACTGGGCAAATTGACAAGAGTACTGTCAAGCCTA
AACCCCAGTTAAGTCATTCCTCTAGACTTTCCTCTGACTTAACTAGAGAAACTGATGAAGCTGCTTTTGAACCAGACTATAATGAAAGTG
ACAGTGAAAGTAATGTTTCTGTAAAAGAAGAGGAATCTTCAGGAAACATTTCTAAGGACCTGAAAGATAAAATAGTGGAGAAAGCAAAAG
AGAGCCTGGACACAGCAGCAGTTGTCCAGGTGGGCATAAGCAGGAATCAGAGCCACAGCAGCCCCAGCGTCAGCCCCAGCAGAAGCCACA
GTCCTTCTGGAAGCCAGACCCGAAGCCACAGTAGCAGTGCCAGCTCAGCAGAAAGTCAGGACAGCAAGAAGAAGAAGAAAAAGAAGGAAA
AGAAAAAACACAAGAAACATAAAAAGCATAAGAAGCATAAGAAACATGCAGGCACTGAAGTGGAATTGGAAAAAAGCCAAAAACACAAAC
ACAAGAAAAAGAAGTCAAAGAAGAACAAAGATAAAGAGAAGGAGAAGGAGAAAGATGACCAAAAAGTGAAATCTGTCACTGTGTAAAAAG
ACAGATTTTTTAAATTGACTTAATTACTAAGTCATCTGTATTAAATTTTGTTATAATGTAAAGAGATTCAAGCCTTGTAAATAATGACAT
GGAAGACCCTGTGCTGCACTTAAAATATTGCTGCTTGATTATTTGATTTTTACATCAGAGCTTTATAACACGAACTTTTGTACAGAATTG
TGAGTTGTGACCATGTAACATGAGAGGTTTTGCTAGGGCCTATTATTTTTAACCACCATTAATTAGTTGGGGTGGAGTTTACTGTAATGT
GAAATTTTCACATTTGAATTTTTTAATTGCCTGGCAAAAGCTGATATAAGTTCTAAAATATCAGCAGAATGATTTGCTGAATTCATTACA

>39565_39565_13_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000543915_RBBP6_chr16_24557483_ENST00000319715_length(amino acids)=1760AA_BP=1691
MGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANLAE
ANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGAML
TNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCHQN
DVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQS
SLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLLHG
QLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTL
PLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKKSKLDEFT
NDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHG
YHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYY
KGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNK
HKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRK
NDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKK
DYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISL
SAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTV
IKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSH
EIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRD
KKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVD
KNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSV
KEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHK

--------------------------------------------------------------
>39565_39565_14_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000543915_RBBP6_chr16_24557483_ENST00000348022_length(transcript)=5712nt_BP=183nt
AAAGCCCCGCGCGGCGCGGGCCAGGGAAGGGCCACCCAGGGGTCCCCCACTTCCCGCTTGGGCGCCCGGACGGCGAATGGAGCAGGGGCG
CGCAGGTGCCTTGGCATCTCCCAATGGGGTGGCTTTGCTCTGGGCTCCTGTTCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCT
CTGAATATACTGATGATAATGCTCTGATTCCTAAGAATTCTTCTGTAATTGTTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCA
AGACATATGTTATAAGTCGAACTGAACCAGCGATGGCAACTACAAAAGCAATTGATGACTCTTCCGCGTCTATTTCTCTGGCCCAGCTTA
CAAAGACTGCCAATCTGGCTGAAGCCAATGCTTCTGAAGAAGATAAAATTAAAGCAATGATGTCGCAATCTGGCCATGAATACGACCCAA
TCAATTACATGAAGAAACCTCTAGGTCCACCACCTCCATCTTACACGTGTTTCCGTTGTGGTAAACCTGGACATTATATTAAGAATTGCC
CAACAAATGGGGATAAAAACTTTGAATCTGGTCCTAGGATTAAAAAGAGCACTGGAATTCCCAGAAGTTTCATGATGGAAGTGAAAGATC
CTAATATGAAAGGTGCAATGCTTACCAACACTGGAAAATATGCAATACCAACTATAGATGCAGAAGCATATGCAATTGGGAAGAAAGAGA
AACCTCCCTTCTTACCAGAGGAGCCATCTTCTTCCTCAGAAGAAGATGATCCTATCCCAGATGAATTGTTGTGTCTCATCTGCAAGGATA
TTATGACTGATGCTGTTGTGATTCCCTGCTGTGGAAACAGTTACTGTGATGAATGTATAAGAACAGCACTCCTGGAATCAGATGAGCACA
CATGTCCGACGTGTCATCAAAATGATGTTTCTCCTGATGCTTTAATTGCCAATAAATTTTTACGACAGGCTGTAAATAACTTCAAAAATG
AAACTGGCTATACAAAAAGACTACGAAAACAGTTACCTCCTCCACCACCCCCAATACCACCTCCGAGACCACTGATTCAGAGGAACCTAC
AACCTCTGATGAGATCTCCGATATCAAGACAACAAGATCCTCTTATGATTCCAGTGACATCTTCATCAACTCACCCAGCTCCGTCTATAT
CTTCATTAACTTCTAATCAGTCTTCCTTGGCCCCTCCTGTGTCTGGAAATCCGTCTTCTGCTCCAGCTCCTGTACCTGATATAACTGCAA
CAGTATCCATATCAGTTCATTCAGAAAAATCAGATGGACCTTTTCGGGATTCTGATAATAAAATATTGCCAGCTGCAGCTCTTGCATCAG
AGCACTCAAAGGGAACCTCCTCAATTGCAATTACCGCTCTTATGGAAGAGAAGGGTTACCAGGTGCCTGTTCTTGGAACCCCATCTTTGC
TTGGACAGTCATTATTGCATGGACAGTTGATCCCCACAACTGGTCCAGTAAGAATAAATACTGCTCGTCCAGGTGGTGGTCGACCAGGCT
GGGAACATTCCAACAAACTTGGCTATCTGGTTTCTCCACCACAACAAATTAGAAGAGGGGAGAGGAGCTGCTACAGAAGTATAAACCGTG
GGCGACACCACAGCGAAAGATCACAGAGGACTCAAGGCCCGTCACTACCAGCAACTCCAGTCTTTGTACCTGTTCCACCACCTCCTTTGT
ATCCGCCTCCTCCCCATACACTTCCTCTCCCTCCGGGTGTTCCTCCTCCACAGTTTTCTCCTCAGTTTCCTCCTGGCCAGCCACCACCCG
CTGGGTATAGTGTCCCTCCTCCAGGGTTTCCTCCAGCTCCTGCCAATTTATCAACACCTTGGGTATCATCAGGAGTGCAGACAGCTCATT
CAAATACCATCCCAACAACACAAGCACCACCTTTGTCCAGGGAAGAATTCTATAGAGAGCAGCGACGACTAAAAGAAGAGTCTAAATCTC
CCTATAGTGGTTCTTCGTATTCAAGAAGTTCATATACTTATTCTAAATCAAGATCTGGTTCAACACGTTCACGCTCTTATTCTCGATCAT
TCAGCCGCTCACATTCTCGTTCCTATTCACGGTCACCTCCATACCCCAGAAGAGGCAGAGGCAAGAGCCGCAATTACCGTTCACGGTCTA
GATCTCATGGATATCATCGATCTAGGTCAAGGTCACCCCCTTACAGACGCTATCATTCACGATCAAGATCTCCTCAAGCGTTTAGGGGAC
AGTCTCCTAATAAACGTAATGTACCTCAAGGGGAAACAGAACGTGAATATTTTAATAGATACAGAGAAGTTCCACCACCATATGACATGA
AAGCATATTATGGGAGAAGTGTTGACTTTAGAGACCCATTTGAAAAAGAACGCTACCGAGAATGGGAGAGAAAATATAGAGAGTGGTATG
AAAAATATTATAAAGGTTATGCTGCTGGAGCACAGCCTAGACCCTCAGCAAATAGAGAGAACTTTTCTCCAGAGAGATTTTTGCCACTTA
ACATCAGGAATTCTCCCTTCACAAGAGGCCGCAGAGAAGACTATGTTGGTGGGCAAAGTCATAGAAGTCGAAACATAGGTAGCAACTATC
CAGAAAAGCTTTCAGCAAGAGATGGTCACAATCAGAAGGATAATACAAAGTCAAAAGAGAAGGAGAGTGAAAACGCTCCAGGAGATGGTA
AAGGAAATAAGCATAAGAAACACAGAAAAAGAAGAAAAGGGGAGGAAAGTGAGGGTTTTCTGAACCCAGAGTTATTAGAGACTTCTAGGA
AATCAAGAGAACCTACAGGTGTTGAAGAAAATAAAACAGACTCATTGTTTGTTCTCCCAAGTAGAGATGATGCCACACCTGTTAGAGATG
AACCAATGGATGCAGAATCAATCACTTTTAAATCAGTGTCTGAAAAAGACAAGAGAGAAAGGGATAAACCAAAAGCAAAGGGTGATAAAA
CCAAACGGAAGAATGATGGATCTGCTGTGTCCAAAAAAGAAAATATTGTAAAACCTGCTAAAGGACCCCAAGAAAAAGTAGATGGAGAAC
GTGAGAGATCTCCTCGATCTGAACCTCCAATTAAAAAAGCCAAAGAGGAGACTCCGAAGACTGACAATACTAAATCATCATCTTCCTCTC
AGAAGGATGAAAAAATCACTGGAACCCCCAGAAAAGCTCACTCTAAATCAGCAAAAGAACACCAAGAAACAAAACCAGTCAAAGAGGAAA
AAGTGAAGAAGGACTATTCCAAAGATGTCAAATCAGAAAAGCTAACAACTAAGGAAGAAAAGGCCAAGAAGCCTAATGAGAAAAACAAAC
CACTTGATAATAAGGGAGAAAAAAGAAAAAGAAAAACTGAAGAAAAAGGCGTAGATAAAGATTTTGAGTCTTCTTCAATGAAAATCTCGA
AACTAGAAGTGACTGAAATAGTGAAACCATCACCAAAGCGCAAAATGGAACCTGATACTGAAAAAATGGATAGGACCCCTGAAAAGGACA
AAATTTCTTTAAGTGCGCCAGCCAAAAAAATCAAACTCAACAGAGAAACTGGGAAGAAAATTGGAAGTACAGAAAATATATCAAACACAA
AAGAACCCTCTGAAAAATTGGAGTCAACATCTAGCAAAGTTAAACAAGAAAAAGTCAAAGGAAAGGTCAGACGAAAAGTGACTGGAACTG
AAGGATCCAGCTCAACTCTGGTGGATTACACCAGTACGAGCTCAACTGGAGGCAGTCCTGTGCGGAAATCTGAAGAAAAAACAGATACAA
AGCGAACTGTGATTAAAACGATGGAAGAATATAATAATGACAATACCGCGCCAGCTGAAGATGTTATCATTATGATTCAGGTTCCTCAAT
CCAAATGGGATAAAGATGACTTTGAATCTGAAGAAGAAGATGTTAAATCCACACAGCCTATATCAAGTGTAGGAAAACCTGCTAGTGTTA
TAAAAAATGTTAGTACAAAGCCATCAAATATAGTCAAGTATCCTGAGAAAGAAAGTGAGCCATCCGAGAAAATTCAGAAATTCACCAAGG
ACGTGAGCCATGAAATCATACAACATGAGGTTAAAAGTTCAAAAAACTCTGCATCTAGTGAAAAAGGGAAAACCAAAGATCGAGATTATT
CAGTGTTGGAAAAGGAGAACCCTGAAAAGAGGAAGAACAGCACTCAGCCAGAGAAAGAGAGTAATTTGGACCGTCTGAATGAACAAGGAA
ATTTTAAAAGTCTGTCTCAATCTTCCAAAGAGGCTAGAACGTCAGATAAACATGATTCCACTCGTGCTTCCTCAAATAAAGACTTCACTC
CCAATAGAGACAAAAAAACTGACTATGACACCAGAGAGTATTCAAGTTCCAAACGTAGAGATGAAAAGAATGAATTAACAAGACGAAAAG
ACTCTCCTTCTCGGAATAAAGATTCTGCATCTGGACAGAAAAATAAACCAAGGGAAGAGAGAGATTTGCCTAAAAAAGGAACAGGAGATT
CCAAAAAAAGTAATTCTAGTCCCTCAAGAGACAGAAAACCTCATGATCACAAAGCCACTTATGATACTAAACGGCCAAATGAAGAGACAA
AATCTGTAGATAAAAATCCTTGTAAGGATCGTGAGAAGCATGTATTAGAAGCAAGGAACAATAAAGAGTCAAGTGGCAATAAACTACTTT
ATATACTTAACCCACCAGAGACACAGGTTGAAAAAGAGCAAATTACTGGGCAAATTGACAAGAGTACTGTCAAGCCTAAACCCCAGTTAA
GTCATTCCTCTAGACTTTCCTCTGACTTAACTAGAGAAACTGATGAAGCTGCTTTTGAACCAGACTATAATGAAAGTGACAGTGAAAGTA
ATGTTTCTGTAAAAGAAGAGGAATCTTCAGGAAACATTTCTAAGGACCTGAAAGATAAAATAGTGGAGAAAGCAAAAGAGAGCCTGGACA
CAGCAGCAGTTGTCCAGGTGGGCATAAGCAGGAATCAGAGCCACAGCAGCCCCAGCGTCAGCCCCAGCAGAAGCCACAGTCCTTCTGGAA
GCCAGACCCGAAGCCACAGTAGCAGTGCCAGCTCAGCAGAAAGTCAGGACAGCAAGAAGAAGAAGAAAAAGAAGGAAAAGAAAAAACACA
AGAAACATAAAAAGCATAAGAAGCATAAGAAACATGCAGGCACTGAAGTGGAATTGGAAAAAAGCCAAAAACACAAACACAAGAAAAAGA
AGTCAAAGAAGAACAAAGATAAAGAGAAGGAGAAGGAGAAAGATGACCAAAAAGTGAAATCTGTCACTGTGTAAAAAGACAGATTTTTTA
AATTGACTTAATTACTAAGTCATCTGTATTAAATTTTGTTATAATGTAAAGAGATTCAAGCCTTGTAAATAATGACATGGAAGACCCTGT
GCTGCACTTAAAATATTGCTGCTTGATTATTTGATTTTTACATCAGAGCTTTATAACACGAACTTTTGTACAGAATTGTGAGTTGTGACC
ATGTAACATGAGAGGTTTTGCTAGGGCCTATTATTTTTAACCACCATTAATTAGTTGGGGTGGAGTTTACTGTAATGTGAAATTTTCACA
TTTGAATTTTTTAATTGCCTGGCAAAAGCTGATATAAGTTCTAAAATATCAGCAGAATGATTTGCTGAATTCATTACAACCCTGTTATGT

>39565_39565_14_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000543915_RBBP6_chr16_24557483_ENST00000348022_length(amino acids)=1726AA_BP=1657
MGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANLAE
ANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGAML
TNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCHQN
DVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQS
SLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKILPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLLHG
QLIPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTL
PLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSPYSGSSYS
RSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNV
PQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFT
RGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGV
EENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSE
PPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEK
RKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLE
STSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDF
ESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENP
EKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKD
SASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPET
QVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVG
ISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDK

--------------------------------------------------------------
>39565_39565_15_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000543915_RBBP6_chr16_24557483_ENST00000381039_length(transcript)=3294nt_BP=183nt
AAAGCCCCGCGCGGCGCGGGCCAGGGAAGGGCCACCCAGGGGTCCCCCACTTCCCGCTTGGGCGCCCGGACGGCGAATGGAGCAGGGGCG
CGCAGGTGCCTTGGCATCTCCCAATGGGGTGGCTTTGCTCTGGGCTCCTGTTCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCT
CTGAATATACTGATGATAATGCTCTGATTCCTAAGAATTCTTCTGTAATTGTTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCA
AGACATATGTTATAAGTCGAACTGAACCAGCGATGGCAACTACAAAAGCAATTGATGACTCTTCCGCGTCTATTTCTCTGGCCCAGCTTA
CAAAGACTGCCAATCTGGCTGAAGCCAATGCTTCTGAAGAAGATAAAATTAAAGCAATGATGTCGCAATCTGGCCATGAATACGACCCAA
TCAATTACATGAAGAAACCTCTAGGTCCACCACCTCCATCTTACACGTGTTTCCGTTGTGGTAAACCTGGACATTATATTAAGAATTGCC
CAACAAATGGGGATAAAAACTTTGAATCTGGTCCTAGGATTAAAAAGAGCACTGGAATTCCCAGAAGTTTCATGATGGAAGTGAAAGATC
CTAATATGAAAGGTGCAATGCTTACCAACACTGGAAAATATGCAATACCAACTATAGATGCAGAAGCATATGCAATTGGGAAGAAAGAGA
AACCTCCCTTCTTACCAGAGGAGCCATCTTCTTCCTCAGAAGAAGATGATCCTATCCCAGATGAATTGTTGTGTCTCATCTGCAAGGATA
TTATGACTGATGCTGTTGTGATTCCCTGCTGTGGAAACAGTTACTGTGATGAATGTATAAGAACAGCACTCCTGGAATCAGATGAGCACA
CATGTCCGACGTGTCATCAAAATGATGTTTCTCCTGATGCTTTAATTGCCAATAAATTTTTACGACAGGCTGTAAATAACTTCAAAAATG
AAACTGGCTATACAAAAAGACTACGAAAACAGTTACCTCCTCCACCACCCCCAATACCACCTCCGAGACCACTGATTCAGAGGAACCTAC
AACCTCTGATGAGATCTCCGATATCAAGACAACAAGATCCTCTTATGATTCCAGTGACATCTTCATCAACTCACCCAGCTCCGTCTATAT
CTTCATTAACTTCTAATCAGTCTTCCTTGGCCCCTCCTGTGTCTGGAAATCCGTCTTCTGCTCCAGCTCCTGTACCTGATATAACTGCAA
CAGTATCCATATCAGTTCATTCAGAAAAATCAGATGGACCTTTTCGTACGAGCTCAACTGGAGGCAGTCCTGTGCGGAAATCTGAAGAAA
AAACAGATACAAAGCGAACTGTGATTAAAACGATGGAAGAATATAATAATGACAATACCGCGCCAGCTGAAGATGTTATCATTATGATTC
AGGTTCCTCAATCCAAATGGGATAAAGATGACTTTGAATCTGAAGAAGAAGATGTTAAATCCACACAGCCTATATCAAGTGTAGGAAAAC
CTGCTAGTGTTATAAAAAATGTTAGTACAAAGCCATCAAATATAGTCAAGTATCCTGAGAAAGAAAGTGAGCCATCCGAGAAAATTCAGA
AATTCACCAAGGACGTGAGCCATGAAATCATACAACATGAGGTTAAAAGTTCAAAAAACTCTGCATCTAGTGAAAAAGGGAAAACCAAAG
ATCGAGATTATTCAGTGTTGGAAAAGGAGAACCCTGAAAAGAGGAAGAACAGCACTCAGCCAGAGAAAGAGAGTAATTTGGACCGTCTGA
ATGAACAAGGAAATTTTAAAAGTCTGTCTCAATCTTCCAAAGAGGCTAGAACGTCAGATAAACATGATTCCACTCGTGCTTCCTCAAATA
AAGACTTCACTCCCAATAGAGACAAAAAAACTGACTATGACACCAGAGAGTATTCAAGTTCCAAACGTAGAGATGAAAAGAATGAATTAA
CAAGACGAAAAGACTCTCCTTCTCGGAATAAAGATTCTGCATCTGGACAGAAAAATAAACCAAGGGAAGAGAGAGATTTGCCTAAAAAAG
GAACAGGAGATTCCAAAAAAAGTAATTCTAGTCCCTCAAGAGACAGAAAACCTCATGATCACAAAGCCACTTATGATACTAAACGGCCAA
ATGAAGAGACAAAATCTGTAGATAAAAATCCTTGTAAGGATCGTGAGAAGCATGTATTAGAAGCAAGGAACAATAAAGAGTCAAGTGGCA
ATAAACTACTTTATATACTTAACCCACCAGAGACACAGGTTGAAAAAGAGCAAATTACTGGGCAAATTGACAAGAGTACTGTCAAGCCTA
AACCCCAGTTAAGTCATTCCTCTAGACTTTCCTCTGACTTAACTAGAGAAACTGATGAAGCTGCTTTTGAACCAGACTATAATGAAAGTG
ACAGTGAAAGTAATGTTTCTGTAAAAGAAGAGGAATCTTCAGGAAACATTTCTAAGGACCTGAAAGATAAAATAGTGGAGAAAGCAAAAG
AGAGCCTGGACACAGCAGCAGTTGTCCAGGTGGGCATAAGCAGGAATCAGAGCCACAGCAGCCCCAGCGTCAGCCCCAGCAGAAGCCACA
GTCCTTCTGGAAGCCAGACCCGAAGCCACAGTAGCAGTGCCAGCTCAGCAGAAAGTCAGGACAGCAAGAAGAAGAAGAAAAAGAAGGAAA
AGAAAAAACACAAGAAACATAAAAAGCATAAGAAGCATAAGAAACATGCAGGCACTGAAGTGGAATTGGAAAAAAGCCAAAAACACAAAC
ACAAGAAAAAGAAGTCAAAGAAGAACAAAGATAAAGAGAAGGAGAAGGAGAAAGATGACCAAAAAGTGAAATCTGTCACTGTGTAAAAAG
ACAGATTTTTTAAATTGACTTAATTACTAAGTCATCTGTATTAAATTTTGTTATAATGTAAAGAGATTCAAGCCTTGTAAATAATGACAT
GGAAGACCCTGTGCTGCACTTAAAATATTGCTGCTTGATTATTTGATTTTTACATCAGAGCTTTATAACACGAACTTTTGTACAGAATTG
TGAGTTGTGACCATGTAACATGAGAGGTTTTGCTAGGGCCTATTATTTTTAACCACCATTAATTAGTTGGGGTGGAGTTTACTGTAATGT
GAAATTTTCACATTTGAATTTTTTAATTGCCTGGCAAAAGCTGATATAAGTTCTAAAATATCAGCAGAATGATTTGCTGAATTCATTACA

>39565_39565_15_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000543915_RBBP6_chr16_24557483_ENST00000381039_length(amino acids)=920AA_BP=851
MGWLCSGLLFPVSCLVLLQVASSEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASISLAQLTKTANLAE
ANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYTCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGAML
TNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCHQN
DVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQS
SLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWD
KDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLE
KENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPS
RNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILN
PPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAV
VQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKK

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>39565_39565_16_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000543915_RBBP6_chr16_24557483_ENST00000452655_length(transcript)=740nt_BP=183nt
AAAGCCCCGCGCGGCGCGGGCCAGGGAAGGGCCACCCAGGGGTCCCCCACTTCCCGCTTGGGCGCCCGGACGGCGAATGGAGCAGGGGCG
CGCAGGTGCCTTGGCATCTCCCAATGGGGTGGCTTTGCTCTGGGCTCCTGTTCCCTGTGAGCTGCCTGGTCCTGCTGCAGGTGGCAAGCT
CTGAATATACTGATGATAATGCTCTGATTCCTAAGAATTCTTCTGTAATTGTTAGAAGAATTCCTATTGGAGGTGTTAAATCTACAAGCA
AGACATATGTTATAAGTCGAACTGAACCAGCGATGGCAACTACAAAAGCAGTATGTAAAAACACAATCTCACACTTTTTCTACACATTGC
TTTTACCTTTATAATGTAGCAGTGAAGTAAATCATTTTAGAACTTAATATCCAACTGATCATAGTACATATTGTAAATAAAATGTATTTT
GATGACAGCTCAGTTGAATATGGATAATATGTGGCATCACTTGCACACTTATTTTGTAGAAATGGGTAATTTGTGCCCGTAACACTGTTT
CATATTAAATATGATAGCATTATCCCTGTATGACACTGTGTTGTACAGTTAATGTATGATCCTTTTTAGATCGTTTAGGTTTTACACTAA
GGAACATGATGACATGTTCTACATTTGTCTGTCTATAGTTAGTATTTTGTATGTATGTACAGGCTGTTGTGTGCTTTTTGTTTCTTGCAA

>39565_39565_16_IL4R-RBBP6_IL4R_chr16_27351594_ENST00000543915_RBBP6_chr16_24557483_ENST00000452655_length(amino acids)=90AA_BP=1
MLVDLTPPIGILLTITEEFLGIRALSSVYSELATCSRTRQLTGNRSPEQSHPIGRCQGTCAPLLHSPSGRPSGKWGTPGWPFPGPRRAGL

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Fusion Gene PPI Analysis for IL4R-RBBP6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneRBBP6chr16:27351594chr16:24557483ENST000003197150181433_154455.3333333333333361793.0p53
TgeneRBBP6chr16:27351594chr16:24557483ENST000003480220171433_154455.3333333333333361759.0p53
TgeneRBBP6chr16:27351594chr16:24557483ENST000003810390111433_154455.333333333333336953.0p53
TgeneRBBP6chr16:27351594chr16:24557483ENST00000452655031433_154455.333333333333336119.0p53
TgeneRBBP6chr16:27351594chr16:24557483ENST00000319715018982_113955.3333333333333361793.0RB1
TgeneRBBP6chr16:27351594chr16:24557483ENST00000348022017982_113955.3333333333333361759.0RB1
TgeneRBBP6chr16:27351594chr16:24557483ENST00000381039011982_113955.333333333333336953.0RB1
TgeneRBBP6chr16:27351594chr16:24557483ENST0000045265503982_113955.333333333333336119.0RB1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for IL4R-RBBP6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for IL4R-RBBP6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource