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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:IL6ST-SKIV2L2 (FusionGDB2 ID:39593)

Fusion Gene Summary for IL6ST-SKIV2L2

check button Fusion gene summary
Fusion gene informationFusion gene name: IL6ST-SKIV2L2
Fusion gene ID: 39593
HgeneTgene
Gene symbol

IL6ST

SKIV2L2

Gene ID

3572

23517

Gene nameinterleukin 6 signal transducerMtr4 exosome RNA helicase
SynonymsCD130|CDW130|GP130|HIES4|IL-6RB|sGP130Dob1|KIAA0052|Mtr4|SKIV2L2|fSAP118
Cytomap

5q11.2

5q11.2

Type of geneprotein-codingprotein-coding
Descriptioninterleukin-6 receptor subunit betaCD130 antigenIL-6 receptor subunit betaIL-6R subunit betagp130 of the rheumatoid arthritis antigenic peptide-bearing soluble formgp130, oncostatin M receptorinterleukin receptor beta chainmembrane glycoprotein 130exosome RNA helicase MTR4ATP-dependent RNA helicase DOB1ATP-dependent RNA helicase SKIV2L2ATP-dependent helicase SKIV2L2Ski2 like RNA helicase 2TRAMP-like complex helicasefunctional spliceosome-associated protein 118superkiller viralicidic activity
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000381287, ENST00000522633, 
ENST00000536319, ENST00000336909, 
ENST00000381294, ENST00000381298, 
ENST00000502326, ENST00000381286, 
ENST00000381293, ENST00000396816, 
ENST00000577363, 		ENST00000230640, 
ENST00000545714, ENST00000504388, 
Fusion gene scores* DoF score16 X 11 X 5=8809 X 8 X 7=504
# samples 199
** MAII scorelog2(19/880*10)=-2.21150410519371
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/504*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: IL6ST [Title/Abstract] AND SKIV2L2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointIL6ST(55251853)-SKIV2L2(54639159), # samples:1
Anticipated loss of major functional domain due to fusion event.IL6ST-SKIV2L2 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
IL6ST-SKIV2L2 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
IL6ST-SKIV2L2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneIL6ST

GO:0008284

positive regulation of cell proliferation

2261637

HgeneIL6ST

GO:0019221

cytokine-mediated signaling pathway

2261637

HgeneIL6ST

GO:0034097

response to cytokine

2261637|8999038

HgeneIL6ST

GO:0048861

leukemia inhibitory factor signaling pathway

8999038|12643274

HgeneIL6ST

GO:0070120

ciliary neurotrophic factor-mediated signaling pathway

12643274

TgeneSKIV2L2

GO:0006401

RNA catabolic process

29906447


check buttonFusion gene breakpoints across IL6ST (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SKIV2L2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AR-A0TZ-01AIL6STchr5

55251853

-SKIV2L2chr5

54639159

+


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Fusion Gene ORF analysis for IL6ST-SKIV2L2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000381287ENST00000230640IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
3UTR-3CDSENST00000381287ENST00000545714IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
3UTR-3CDSENST00000522633ENST00000230640IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
3UTR-3CDSENST00000522633ENST00000545714IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
3UTR-3CDSENST00000536319ENST00000230640IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
3UTR-3CDSENST00000536319ENST00000545714IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
3UTR-intronENST00000381287ENST00000504388IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
3UTR-intronENST00000522633ENST00000504388IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
3UTR-intronENST00000536319ENST00000504388IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
5CDS-intronENST00000336909ENST00000504388IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
5CDS-intronENST00000381294ENST00000504388IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
5CDS-intronENST00000381298ENST00000504388IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
5CDS-intronENST00000502326ENST00000504388IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
Frame-shiftENST00000502326ENST00000230640IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
Frame-shiftENST00000502326ENST00000545714IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
In-frameENST00000336909ENST00000230640IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
In-frameENST00000336909ENST00000545714IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
In-frameENST00000381294ENST00000230640IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
In-frameENST00000381294ENST00000545714IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
In-frameENST00000381298ENST00000230640IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
In-frameENST00000381298ENST00000545714IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
intron-3CDSENST00000381286ENST00000230640IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
intron-3CDSENST00000381286ENST00000545714IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
intron-3CDSENST00000381293ENST00000230640IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
intron-3CDSENST00000381293ENST00000545714IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
intron-3CDSENST00000396816ENST00000230640IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
intron-3CDSENST00000396816ENST00000545714IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
intron-3CDSENST00000577363ENST00000230640IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
intron-3CDSENST00000577363ENST00000545714IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
intron-intronENST00000381286ENST00000504388IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
intron-intronENST00000381293ENST00000504388IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
intron-intronENST00000396816ENST00000504388IL6STchr5

55251853

-SKIV2L2chr5

54639159

+
intron-intronENST00000577363ENST00000504388IL6STchr5

55251853

-SKIV2L2chr5

54639159

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000381298IL6STchr555251853-ENST00000230640SKIV2L2chr554639159+4737158031339271204
ENST00000381298IL6STchr555251853-ENST00000545714SKIV2L2chr554639159+4262158031339271204
ENST00000336909IL6STchr555251853-ENST00000230640SKIV2L2chr554639159+44601303636501214
ENST00000336909IL6STchr555251853-ENST00000545714SKIV2L2chr554639159+39851303636501214
ENST00000381294IL6STchr555251853-ENST00000230640SKIV2L2chr554639159+44241267036141204
ENST00000381294IL6STchr555251853-ENST00000545714SKIV2L2chr554639159+39491267036141204

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000381298ENST00000230640IL6STchr555251853-SKIV2L2chr554639159+0.0001805760.99981946
ENST00000381298ENST00000545714IL6STchr555251853-SKIV2L2chr554639159+0.0002098410.99979013
ENST00000336909ENST00000230640IL6STchr555251853-SKIV2L2chr554639159+0.0001370860.9998629
ENST00000336909ENST00000545714IL6STchr555251853-SKIV2L2chr554639159+0.0001616070.99983835
ENST00000381294ENST00000230640IL6STchr555251853-SKIV2L2chr554639159+0.0001381840.99986184
ENST00000381294ENST00000545714IL6STchr555251853-SKIV2L2chr554639159+0.000161750.99983823

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Fusion Genomic Features for IL6ST-SKIV2L2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
IL6STchr555251852-SKIV2L2chr554639158+1.70E-070.9999999
IL6STchr555251852-SKIV2L2chr554639158+1.70E-070.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for IL6ST-SKIV2L2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:55251853/chr5:54639159)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIL6STchr5:55251853chr5:54639159ENST00000522633-813725_755394299.3333333333333Compositional biasNote=Ser-rich
HgeneIL6STchr5:55251853chr5:54639159ENST00000336909-815125_216422919.0DomainFibronectin type-III 1
HgeneIL6STchr5:55251853chr5:54639159ENST00000336909-815224_324422919.0DomainFibronectin type-III 2
HgeneIL6STchr5:55251853chr5:54639159ENST00000336909-81526_120422919.0DomainNote=Ig-like C2-type
HgeneIL6STchr5:55251853chr5:54639159ENST00000336909-815329_424422919.0DomainFibronectin type-III 3
HgeneIL6STchr5:55251853chr5:54639159ENST00000381287-714125_2163942415.0DomainFibronectin type-III 1
HgeneIL6STchr5:55251853chr5:54639159ENST00000381287-714224_3243942415.0DomainFibronectin type-III 2
HgeneIL6STchr5:55251853chr5:54639159ENST00000381287-71426_1203942415.0DomainNote=Ig-like C2-type
HgeneIL6STchr5:55251853chr5:54639159ENST00000381294-814125_216422858.0DomainFibronectin type-III 1
HgeneIL6STchr5:55251853chr5:54639159ENST00000381294-814224_324422858.0DomainFibronectin type-III 2
HgeneIL6STchr5:55251853chr5:54639159ENST00000381294-81426_120422858.0DomainNote=Ig-like C2-type
HgeneIL6STchr5:55251853chr5:54639159ENST00000381294-814329_424422858.0DomainFibronectin type-III 3
HgeneIL6STchr5:55251853chr5:54639159ENST00000381298-1017125_216422919.0DomainFibronectin type-III 1
HgeneIL6STchr5:55251853chr5:54639159ENST00000381298-1017224_324422919.0DomainFibronectin type-III 2
HgeneIL6STchr5:55251853chr5:54639159ENST00000381298-101726_120422919.0DomainNote=Ig-like C2-type
HgeneIL6STchr5:55251853chr5:54639159ENST00000381298-1017329_424422919.0DomainFibronectin type-III 3
HgeneIL6STchr5:55251853chr5:54639159ENST00000502326-916125_216422919.0DomainFibronectin type-III 1
HgeneIL6STchr5:55251853chr5:54639159ENST00000502326-916224_324422919.0DomainFibronectin type-III 2
HgeneIL6STchr5:55251853chr5:54639159ENST00000502326-91626_120422919.0DomainNote=Ig-like C2-type
HgeneIL6STchr5:55251853chr5:54639159ENST00000502326-916329_424422919.0DomainFibronectin type-III 3
HgeneIL6STchr5:55251853chr5:54639159ENST00000522633-813125_216394299.3333333333333DomainFibronectin type-III 1
HgeneIL6STchr5:55251853chr5:54639159ENST00000522633-813224_324394299.3333333333333DomainFibronectin type-III 2
HgeneIL6STchr5:55251853chr5:54639159ENST00000522633-81326_120394299.3333333333333DomainNote=Ig-like C2-type
HgeneIL6STchr5:55251853chr5:54639159ENST00000522633-813329_424394299.3333333333333DomainFibronectin type-III 3
HgeneIL6STchr5:55251853chr5:54639159ENST00000522633-813426_517394299.3333333333333DomainFibronectin type-III 4
HgeneIL6STchr5:55251853chr5:54639159ENST00000522633-813518_613394299.3333333333333DomainFibronectin type-III 5
HgeneIL6STchr5:55251853chr5:54639159ENST00000536319-713125_216394441.3333333333333DomainFibronectin type-III 1
HgeneIL6STchr5:55251853chr5:54639159ENST00000536319-713224_324394441.3333333333333DomainFibronectin type-III 2
HgeneIL6STchr5:55251853chr5:54639159ENST00000536319-71326_120394441.3333333333333DomainNote=Ig-like C2-type
HgeneIL6STchr5:55251853chr5:54639159ENST00000336909-815310_314422919.0MotifNote=WSXWS motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000381287-714310_3143942415.0MotifNote=WSXWS motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000381294-814310_314422858.0MotifNote=WSXWS motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000381298-1017310_314422919.0MotifNote=WSXWS motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000502326-916310_314422919.0MotifNote=WSXWS motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000522633-813310_314394299.3333333333333MotifNote=WSXWS motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000522633-813651_659394299.3333333333333MotifNote=Box 1 motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000536319-713310_314394441.3333333333333MotifNote=WSXWS motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000522633-81323_619394299.3333333333333Topological domainExtracellular
HgeneIL6STchr5:55251853chr5:54639159ENST00000522633-813642_918394299.3333333333333Topological domainCytoplasmic
HgeneIL6STchr5:55251853chr5:54639159ENST00000522633-813620_641394299.3333333333333TransmembraneHelical
TgeneSKIV2L2chr5:55251853chr5:54639159ENST00000230640627405_5772601043.0DomainHelicase C-terminal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIL6STchr5:55251853chr5:54639159ENST00000336909-815725_755422919.0Compositional biasNote=Ser-rich
HgeneIL6STchr5:55251853chr5:54639159ENST00000381287-714725_7553942415.0Compositional biasNote=Ser-rich
HgeneIL6STchr5:55251853chr5:54639159ENST00000381294-814725_755422858.0Compositional biasNote=Ser-rich
HgeneIL6STchr5:55251853chr5:54639159ENST00000381298-1017725_755422919.0Compositional biasNote=Ser-rich
HgeneIL6STchr5:55251853chr5:54639159ENST00000502326-916725_755422919.0Compositional biasNote=Ser-rich
HgeneIL6STchr5:55251853chr5:54639159ENST00000536319-713725_755394441.3333333333333Compositional biasNote=Ser-rich
HgeneIL6STchr5:55251853chr5:54639159ENST00000336909-815426_517422919.0DomainFibronectin type-III 4
HgeneIL6STchr5:55251853chr5:54639159ENST00000336909-815518_613422919.0DomainFibronectin type-III 5
HgeneIL6STchr5:55251853chr5:54639159ENST00000381287-714329_4243942415.0DomainFibronectin type-III 3
HgeneIL6STchr5:55251853chr5:54639159ENST00000381287-714426_5173942415.0DomainFibronectin type-III 4
HgeneIL6STchr5:55251853chr5:54639159ENST00000381287-714518_6133942415.0DomainFibronectin type-III 5
HgeneIL6STchr5:55251853chr5:54639159ENST00000381294-814426_517422858.0DomainFibronectin type-III 4
HgeneIL6STchr5:55251853chr5:54639159ENST00000381294-814518_613422858.0DomainFibronectin type-III 5
HgeneIL6STchr5:55251853chr5:54639159ENST00000381298-1017426_517422919.0DomainFibronectin type-III 4
HgeneIL6STchr5:55251853chr5:54639159ENST00000381298-1017518_613422919.0DomainFibronectin type-III 5
HgeneIL6STchr5:55251853chr5:54639159ENST00000502326-916426_517422919.0DomainFibronectin type-III 4
HgeneIL6STchr5:55251853chr5:54639159ENST00000502326-916518_613422919.0DomainFibronectin type-III 5
HgeneIL6STchr5:55251853chr5:54639159ENST00000536319-713329_424394441.3333333333333DomainFibronectin type-III 3
HgeneIL6STchr5:55251853chr5:54639159ENST00000536319-713426_517394441.3333333333333DomainFibronectin type-III 4
HgeneIL6STchr5:55251853chr5:54639159ENST00000536319-713518_613394441.3333333333333DomainFibronectin type-III 5
HgeneIL6STchr5:55251853chr5:54639159ENST00000336909-815651_659422919.0MotifNote=Box 1 motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000381287-714651_6593942415.0MotifNote=Box 1 motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000381294-814651_659422858.0MotifNote=Box 1 motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000381298-1017651_659422919.0MotifNote=Box 1 motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000502326-916651_659422919.0MotifNote=Box 1 motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000536319-713651_659394441.3333333333333MotifNote=Box 1 motif
HgeneIL6STchr5:55251853chr5:54639159ENST00000336909-81523_619422919.0Topological domainExtracellular
HgeneIL6STchr5:55251853chr5:54639159ENST00000336909-815642_918422919.0Topological domainCytoplasmic
HgeneIL6STchr5:55251853chr5:54639159ENST00000381287-71423_6193942415.0Topological domainExtracellular
HgeneIL6STchr5:55251853chr5:54639159ENST00000381287-714642_9183942415.0Topological domainCytoplasmic
HgeneIL6STchr5:55251853chr5:54639159ENST00000381294-81423_619422858.0Topological domainExtracellular
HgeneIL6STchr5:55251853chr5:54639159ENST00000381294-814642_918422858.0Topological domainCytoplasmic
HgeneIL6STchr5:55251853chr5:54639159ENST00000381298-101723_619422919.0Topological domainExtracellular
HgeneIL6STchr5:55251853chr5:54639159ENST00000381298-1017642_918422919.0Topological domainCytoplasmic
HgeneIL6STchr5:55251853chr5:54639159ENST00000502326-91623_619422919.0Topological domainExtracellular
HgeneIL6STchr5:55251853chr5:54639159ENST00000502326-916642_918422919.0Topological domainCytoplasmic
HgeneIL6STchr5:55251853chr5:54639159ENST00000536319-71323_619394441.3333333333333Topological domainExtracellular
HgeneIL6STchr5:55251853chr5:54639159ENST00000536319-713642_918394441.3333333333333Topological domainCytoplasmic
HgeneIL6STchr5:55251853chr5:54639159ENST00000336909-815620_641422919.0TransmembraneHelical
HgeneIL6STchr5:55251853chr5:54639159ENST00000381287-714620_6413942415.0TransmembraneHelical
HgeneIL6STchr5:55251853chr5:54639159ENST00000381294-814620_641422858.0TransmembraneHelical
HgeneIL6STchr5:55251853chr5:54639159ENST00000381298-1017620_641422919.0TransmembraneHelical
HgeneIL6STchr5:55251853chr5:54639159ENST00000502326-916620_641422919.0TransmembraneHelical
HgeneIL6STchr5:55251853chr5:54639159ENST00000536319-713620_641394441.3333333333333TransmembraneHelical
TgeneSKIV2L2chr5:55251853chr5:54639159ENST00000230640627148_3042601043.0DomainHelicase ATP-binding
TgeneSKIV2L2chr5:55251853chr5:54639159ENST00000230640627252_2552601043.0MotifNote=DEIH box
TgeneSKIV2L2chr5:55251853chr5:54639159ENST00000230640627161_1682601043.0Nucleotide bindingATP


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Fusion Gene Sequence for IL6ST-SKIV2L2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>39593_39593_1_IL6ST-SKIV2L2_IL6ST_chr5_55251853_ENST00000336909_SKIV2L2_chr5_54639159_ENST00000230640_length(transcript)=4460nt_BP=1303nt
TATTACATGTGTCTGTTGCAGAAATATCCGCGCAAGATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACT
GAATCTACAGGTGAACTTCTAGATCCATGTGGTTATATCAGTCCTGAATCTCCAGTTGTACAACTTCATTCTAATTTCACTGCAGTTTGT
GTGCTAAAGGAAAAATGTATGGATTATTTTCATGTAAATGCTAATTACATTGTCTGGAAAACAAACCATTTTACTATTCCTAAGGAGCAA
TATACTATCATAAACAGAACAGCATCCAGTGTCACCTTTACAGATATAGCTTCATTAAATATTCAGCTCACTTGCAACATTCTTACATTC
GGACAGCTTGAACAGAATGTTTATGGAATCACAATAATTTCAGGCTTGCCTCCAGAAAAACCTAAAAATTTGAGTTGCATTGTGAACGAG
GGGAAGAAAATGAGGTGTGAGTGGGATGGTGGAAGGGAAACACACTTGGAGACAAACTTCACTTTAAAATCTGAATGGGCAACACACAAG
TTTGCTGATTGCAAAGCAAAACGTGACACCCCCACCTCATGCACTGTTGATTATTCTACTGTGTATTTTGTCAACATTGAAGTCTGGGTA
GAAGCAGAGAATGCCCTTGGGAAGGTTACATCAGATCATATCAATTTTGATCCTGTATATAAAGTGAAGCCCAATCCGCCACATAATTTA
TCAGTGATCAACTCAGAGGAACTGTCTAGTATCTTAAAATTGACATGGACCAACCCAAGTATTAAGAGTGTTATAATACTAAAATATAAC
ATTCAATATAGGACCAAAGATGCCTCAACTTGGAGCCAGATTCCTCCTGAAGACACAGCATCCACCCGATCTTCATTCACTGTCCAAGAC
CTTAAACCTTTTACAGAATATGTGTTTAGGATTCGCTGTATGAAGGAAGATGGTAAGGGATACTGGAGTGACTGGAGTGAAGAAGCAAGT
GGGATCACCTATGAAGATAGACCATCTAAAGCACCAAGTTTCTGGTATAAAATAGATCCATCCCATACTCAAGGCTACAGAACTGTACAA
CTCGTGTGGAAGACATTGCCTCCTTTTGAAGCCAATGGAAAAATCTTGGATTATGAAGTGACTCTCACAAGATGGAAATCACATTTACAA
AATTACACAGTTAATGCCACAAAACTGACAGTAAATCTCACAAATGATCGCTATCTAGCAACCCTAACAGTAAGAAATCTTGTTGGCAAA
TCAGATGCAGCTGTTTTAACTATCCCTGCCTGTGACTTTCAAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCTGATAAC
GTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGTCATGTT
ATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAAAATGGT
GACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGGAAAGGA
GGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTTAGTAAG
AAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTCAGTAAT
GCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATTCACCAT
GGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACCTTTGCT
ATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCTGGTGAA
TACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGCCCAACA
ATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTACGTGTA
GAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAGGTAAAG
AATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCCAAATTG
GGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAATGAAGGA
GATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTATGTAGTA
GAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGAGAGATG
CAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGACAATAGA
CAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGCATTCAA
GATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAATTTGGAA
ACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACAGTCCTA
CAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGACGAGTG
GCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAGGCAACA
GCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAAATGCAG
GAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCTCACTTA
ATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGCAGCATAATTCGTTGT
ATGAGGCGCCTGGAAGAATTGCTTCGACAAATGTGTCAAGCAGCAAAAGCCATTGGAAACACTGAGCTGGAAAATAAATTTGCAGAAGGA
ATCACCAAAATCAAGAGAGATATTGTGTTTGCTGCCAGCCTCTACTTGTAGAGTCAGCTAAAGGAATGTGAGATTTTAAATTATTGACCA
CCTGTTTGATTACAGTTGACTACAAATGCCTGCAAGTGTGGATTTGGTTCTCCCATACATTTTAATATGTATTATATTTAAATCAAACAT
CATTCATAGAAAGCATATTACATACATGTTTATACATAAGCATTACATTTTTTTAATAAAAATGTATACAGGTGGGGCACTGTTTTGGTG
GAAGGCTTGGAGTTTTTTTAATGAGTTTAGAGCTATTAGATAACCACTGAGTTAAAGGTAACTATGTACACACAAAGTGTGCATCCAAGA
GGCATAGCAGCAGCAGAAGTCTTTAAAGGCTTGTACACCAGGAAGAAAGATGCATCCTCTTGCCTTGTGGCAATCATTTTCCTTTAGAAA
ACAGGCCAGCTTCACCTGGGCACCCTGCTGCCTTTCAAGGCTGGTGATTGCTCGGATAGTGATTCCCAGTTGTTGGTGTTTCATGCAGAG
TTGTATGAGAGTCCTCCTCTTTTCTTTCTTTAAAAGAAGTTCTTTCTTTGAAGAAATCCGATACATATACAGCCTACAGTGCAAAATATT
TAATGGTATAATTTAGATCAAGTTAAAAACTACATACAAAGTTGTGATCAACAGCATCCTAAGATAAATATAAACAAAAGGATATACTTT
GAGGTGTACAGATTAAGCATATAAAAAATTAGAGACTAACTGGGATTTTTTAAAGATTATTCCAAATTAAGAGTTGCTTTGTTATGCCTT

>39593_39593_1_IL6ST-SKIV2L2_IL6ST_chr5_55251853_ENST00000336909_SKIV2L2_chr5_54639159_ENST00000230640_length(amino acids)=1214AA_BP=430
MCLLQKYPRKMLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYT
IINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFA
DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQ
YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV
WKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQERGVVWEETIILLPDNVH
YVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGT
KGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGG
LLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIG
KQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGK
EIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQV
VPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETV
YTLCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATAL
LSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMR

--------------------------------------------------------------
>39593_39593_2_IL6ST-SKIV2L2_IL6ST_chr5_55251853_ENST00000336909_SKIV2L2_chr5_54639159_ENST00000545714_length(transcript)=3985nt_BP=1303nt
TATTACATGTGTCTGTTGCAGAAATATCCGCGCAAGATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACT
GAATCTACAGGTGAACTTCTAGATCCATGTGGTTATATCAGTCCTGAATCTCCAGTTGTACAACTTCATTCTAATTTCACTGCAGTTTGT
GTGCTAAAGGAAAAATGTATGGATTATTTTCATGTAAATGCTAATTACATTGTCTGGAAAACAAACCATTTTACTATTCCTAAGGAGCAA
TATACTATCATAAACAGAACAGCATCCAGTGTCACCTTTACAGATATAGCTTCATTAAATATTCAGCTCACTTGCAACATTCTTACATTC
GGACAGCTTGAACAGAATGTTTATGGAATCACAATAATTTCAGGCTTGCCTCCAGAAAAACCTAAAAATTTGAGTTGCATTGTGAACGAG
GGGAAGAAAATGAGGTGTGAGTGGGATGGTGGAAGGGAAACACACTTGGAGACAAACTTCACTTTAAAATCTGAATGGGCAACACACAAG
TTTGCTGATTGCAAAGCAAAACGTGACACCCCCACCTCATGCACTGTTGATTATTCTACTGTGTATTTTGTCAACATTGAAGTCTGGGTA
GAAGCAGAGAATGCCCTTGGGAAGGTTACATCAGATCATATCAATTTTGATCCTGTATATAAAGTGAAGCCCAATCCGCCACATAATTTA
TCAGTGATCAACTCAGAGGAACTGTCTAGTATCTTAAAATTGACATGGACCAACCCAAGTATTAAGAGTGTTATAATACTAAAATATAAC
ATTCAATATAGGACCAAAGATGCCTCAACTTGGAGCCAGATTCCTCCTGAAGACACAGCATCCACCCGATCTTCATTCACTGTCCAAGAC
CTTAAACCTTTTACAGAATATGTGTTTAGGATTCGCTGTATGAAGGAAGATGGTAAGGGATACTGGAGTGACTGGAGTGAAGAAGCAAGT
GGGATCACCTATGAAGATAGACCATCTAAAGCACCAAGTTTCTGGTATAAAATAGATCCATCCCATACTCAAGGCTACAGAACTGTACAA
CTCGTGTGGAAGACATTGCCTCCTTTTGAAGCCAATGGAAAAATCTTGGATTATGAAGTGACTCTCACAAGATGGAAATCACATTTACAA
AATTACACAGTTAATGCCACAAAACTGACAGTAAATCTCACAAATGATCGCTATCTAGCAACCCTAACAGTAAGAAATCTTGTTGGCAAA
TCAGATGCAGCTGTTTTAACTATCCCTGCCTGTGACTTTCAAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCTGATAAC
GTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGTCATGTT
ATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAAAATGGT
GACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGGAAAGGA
GGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTTAGTAAG
AAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTCAGTAAT
GCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATTCACCAT
GGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACCTTTGCT
ATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCTGGTGAA
TACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGCCCAACA
ATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTACGTGTA
GAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAGGTAAAG
AATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCCAAATTG
GGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAATGAAGGA
GATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTATGTAGTA
GAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGAGAGATG
CAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGACAATAGA
CAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGCATTCAA
GATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAATTTGGAA
ACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACAGTCCTA
CAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGACGAGTG
GCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAGGCAACA
GCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAAATGCAG
GAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCTCACTTA
ATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGCAGCATAATTCGTTGT
ATGAGGCGCCTGGAAGAATTGCTTCGACAAATGTGTCAAGCAGCAAAAGCCATTGGAAACACTGAGCTGGAAAATAAATTTGCAGAAGGA
ATCACCAAAATCAAGAGAGATATTGTGTTTGCTGCCAGCCTCTACTTGTAGAGTCAGCTAAAGGAATGTGAGATTTTAAATTATTGACCA
CCTGTTTGATTACAGTTGACTACAAATGCCTGCAAGTGTGGATTTGGTTCTCCCATACATTTTAATATGTATTATATTTAAATCAAACAT
CATTCATAGAAAGCATATTACATACATGTTTATACATAAGCATTACATTTTTTTAATAAAAATGTATACAGGTGGGGCACTGTTTTGGTG
GAAGGCTTGGAGTTTTTTTAATGAGTTTAGAGCTATTAGATAACCACTGAGTTAAAGGTAACTATGTACACACAAAGTGTGCATCCAAGA

>39593_39593_2_IL6ST-SKIV2L2_IL6ST_chr5_55251853_ENST00000336909_SKIV2L2_chr5_54639159_ENST00000545714_length(amino acids)=1214AA_BP=430
MCLLQKYPRKMLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYT
IINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFA
DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQ
YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV
WKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQERGVVWEETIILLPDNVH
YVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGT
KGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGG
LLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIG
KQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGK
EIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQV
VPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETV
YTLCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATAL
LSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMR

--------------------------------------------------------------
>39593_39593_3_IL6ST-SKIV2L2_IL6ST_chr5_55251853_ENST00000381294_SKIV2L2_chr5_54639159_ENST00000230640_length(transcript)=4424nt_BP=1267nt
ATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACTGAATCTACAGGTGAACTTCTAGATCCATGTGGTTAT
ATCAGTCCTGAATCTCCAGTTGTACAACTTCATTCTAATTTCACTGCAGTTTGTGTGCTAAAGGAAAAATGTATGGATTATTTTCATGTA
AATGCTAATTACATTGTCTGGAAAACAAACCATTTTACTATTCCTAAGGAGCAATATACTATCATAAACAGAACAGCATCCAGTGTCACC
TTTACAGATATAGCTTCATTAAATATTCAGCTCACTTGCAACATTCTTACATTCGGACAGCTTGAACAGAATGTTTATGGAATCACAATA
ATTTCAGGCTTGCCTCCAGAAAAACCTAAAAATTTGAGTTGCATTGTGAACGAGGGGAAGAAAATGAGGTGTGAGTGGGATGGTGGAAGG
GAAACACACTTGGAGACAAACTTCACTTTAAAATCTGAATGGGCAACACACAAGTTTGCTGATTGCAAAGCAAAACGTGACACCCCCACC
TCATGCACTGTTGATTATTCTACTGTGTATTTTGTCAACATTGAAGTCTGGGTAGAAGCAGAGAATGCCCTTGGGAAGGTTACATCAGAT
CATATCAATTTTGATCCTGTATATAAAGTGAAGCCCAATCCGCCACATAATTTATCAGTGATCAACTCAGAGGAACTGTCTAGTATCTTA
AAATTGACATGGACCAACCCAAGTATTAAGAGTGTTATAATACTAAAATATAACATTCAATATAGGACCAAAGATGCCTCAACTTGGAGC
CAGATTCCTCCTGAAGACACAGCATCCACCCGATCTTCATTCACTGTCCAAGACCTTAAACCTTTTACAGAATATGTGTTTAGGATTCGC
TGTATGAAGGAAGATGGTAAGGGATACTGGAGTGACTGGAGTGAAGAAGCAAGTGGGATCACCTATGAAGATAGACCATCTAAAGCACCA
AGTTTCTGGTATAAAATAGATCCATCCCATACTCAAGGCTACAGAACTGTACAACTCGTGTGGAAGACATTGCCTCCTTTTGAAGCCAAT
GGAAAAATCTTGGATTATGAAGTGACTCTCACAAGATGGAAATCACATTTACAAAATTACACAGTTAATGCCACAAAACTGACAGTAAAT
CTCACAAATGATCGCTATCTAGCAACCCTAACAGTAAGAAATCTTGTTGGCAAATCAGATGCAGCTGTTTTAACTATCCCTGCCTGTGAC
TTTCAAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCTGATAACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAAT
GCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGTCATGTTATTTACACAGATTATCGGCCCACTCCATTGCAACAC
TACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAAAATGGTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAA
GTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGGAAAGGAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTG
AAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTTAGTAAGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAA
TTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTCAGTAATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTC
CCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATTCACCATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAA
ATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACCTTTGCTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTT
ACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCTGGTGAATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGA
ATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGCCCAACAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCT
CTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTACGTGTAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCC
TTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAGGTAAAGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCC
AATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCCAAATTGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAA
TACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAATGAAGGAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCA
AAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTATGTAGTAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAA
AATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGAGAGATGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCT
ATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGACAATAGACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAA
CGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGCATTCAAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAA
GCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAATTTGGAAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATT
GCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACAGTCCTACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTA
AGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGACGAGTGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTA
ACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAGGCAACAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCT
AGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAAATGCAGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAA
GCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCTCACTTAATGGATGTAGTATATACCTGGGCAACTGGAGCTACA
TTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGCAGCATAATTCGTTGTATGAGGCGCCTGGAAGAATTGCTTCGACAAATGTGT
CAAGCAGCAAAAGCCATTGGAAACACTGAGCTGGAAAATAAATTTGCAGAAGGAATCACCAAAATCAAGAGAGATATTGTGTTTGCTGCC
AGCCTCTACTTGTAGAGTCAGCTAAAGGAATGTGAGATTTTAAATTATTGACCACCTGTTTGATTACAGTTGACTACAAATGCCTGCAAG
TGTGGATTTGGTTCTCCCATACATTTTAATATGTATTATATTTAAATCAAACATCATTCATAGAAAGCATATTACATACATGTTTATACA
TAAGCATTACATTTTTTTAATAAAAATGTATACAGGTGGGGCACTGTTTTGGTGGAAGGCTTGGAGTTTTTTTAATGAGTTTAGAGCTAT
TAGATAACCACTGAGTTAAAGGTAACTATGTACACACAAAGTGTGCATCCAAGAGGCATAGCAGCAGCAGAAGTCTTTAAAGGCTTGTAC
ACCAGGAAGAAAGATGCATCCTCTTGCCTTGTGGCAATCATTTTCCTTTAGAAAACAGGCCAGCTTCACCTGGGCACCCTGCTGCCTTTC
AAGGCTGGTGATTGCTCGGATAGTGATTCCCAGTTGTTGGTGTTTCATGCAGAGTTGTATGAGAGTCCTCCTCTTTTCTTTCTTTAAAAG
AAGTTCTTTCTTTGAAGAAATCCGATACATATACAGCCTACAGTGCAAAATATTTAATGGTATAATTTAGATCAAGTTAAAAACTACATA
CAAAGTTGTGATCAACAGCATCCTAAGATAAATATAAACAAAAGGATATACTTTGAGGTGTACAGATTAAGCATATAAAAAATTAGAGAC
TAACTGGGATTTTTTAAAGATTATTCCAAATTAAGAGTTGCTTTGTTATGCCTTCAGCAAATAGCTTCATTTTGCCAATACTGAATAAAA

>39593_39593_3_IL6ST-SKIV2L2_IL6ST_chr5_55251853_ENST00000381294_SKIV2L2_chr5_54639159_ENST00000230640_length(amino acids)=1204AA_BP=420
MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT
FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT
SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS
QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN
GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQERGVVWEETIILLPDNVHYVFLSATIPN
ARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIV
KMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIE
ILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADP
LNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPK
YCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSA
ISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQI
AIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENS
SEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMC

--------------------------------------------------------------
>39593_39593_4_IL6ST-SKIV2L2_IL6ST_chr5_55251853_ENST00000381294_SKIV2L2_chr5_54639159_ENST00000545714_length(transcript)=3949nt_BP=1267nt
ATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACTGAATCTACAGGTGAACTTCTAGATCCATGTGGTTAT
ATCAGTCCTGAATCTCCAGTTGTACAACTTCATTCTAATTTCACTGCAGTTTGTGTGCTAAAGGAAAAATGTATGGATTATTTTCATGTA
AATGCTAATTACATTGTCTGGAAAACAAACCATTTTACTATTCCTAAGGAGCAATATACTATCATAAACAGAACAGCATCCAGTGTCACC
TTTACAGATATAGCTTCATTAAATATTCAGCTCACTTGCAACATTCTTACATTCGGACAGCTTGAACAGAATGTTTATGGAATCACAATA
ATTTCAGGCTTGCCTCCAGAAAAACCTAAAAATTTGAGTTGCATTGTGAACGAGGGGAAGAAAATGAGGTGTGAGTGGGATGGTGGAAGG
GAAACACACTTGGAGACAAACTTCACTTTAAAATCTGAATGGGCAACACACAAGTTTGCTGATTGCAAAGCAAAACGTGACACCCCCACC
TCATGCACTGTTGATTATTCTACTGTGTATTTTGTCAACATTGAAGTCTGGGTAGAAGCAGAGAATGCCCTTGGGAAGGTTACATCAGAT
CATATCAATTTTGATCCTGTATATAAAGTGAAGCCCAATCCGCCACATAATTTATCAGTGATCAACTCAGAGGAACTGTCTAGTATCTTA
AAATTGACATGGACCAACCCAAGTATTAAGAGTGTTATAATACTAAAATATAACATTCAATATAGGACCAAAGATGCCTCAACTTGGAGC
CAGATTCCTCCTGAAGACACAGCATCCACCCGATCTTCATTCACTGTCCAAGACCTTAAACCTTTTACAGAATATGTGTTTAGGATTCGC
TGTATGAAGGAAGATGGTAAGGGATACTGGAGTGACTGGAGTGAAGAAGCAAGTGGGATCACCTATGAAGATAGACCATCTAAAGCACCA
AGTTTCTGGTATAAAATAGATCCATCCCATACTCAAGGCTACAGAACTGTACAACTCGTGTGGAAGACATTGCCTCCTTTTGAAGCCAAT
GGAAAAATCTTGGATTATGAAGTGACTCTCACAAGATGGAAATCACATTTACAAAATTACACAGTTAATGCCACAAAACTGACAGTAAAT
CTCACAAATGATCGCTATCTAGCAACCCTAACAGTAAGAAATCTTGTTGGCAAATCAGATGCAGCTGTTTTAACTATCCCTGCCTGTGAC
TTTCAAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCTGATAACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAAT
GCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGTCATGTTATTTACACAGATTATCGGCCCACTCCATTGCAACAC
TACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAAAATGGTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAA
GTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGGAAAGGAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTG
AAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTTAGTAAGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAA
TTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTCAGTAATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTC
CCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATTCACCATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAA
ATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACCTTTGCTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTT
ACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCTGGTGAATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGA
ATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGCCCAACAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCT
CTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTACGTGTAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCC
TTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAGGTAAAGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCC
AATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCCAAATTGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAA
TACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAATGAAGGAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCA
AAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTATGTAGTAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAA
AATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGAGAGATGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCT
ATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGACAATAGACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAA
CGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGCATTCAAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAA
GCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAATTTGGAAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATT
GCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACAGTCCTACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTA
AGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGACGAGTGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTA
ACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAGGCAACAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCT
AGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAAATGCAGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAA
GCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCTCACTTAATGGATGTAGTATATACCTGGGCAACTGGAGCTACA
TTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGCAGCATAATTCGTTGTATGAGGCGCCTGGAAGAATTGCTTCGACAAATGTGT
CAAGCAGCAAAAGCCATTGGAAACACTGAGCTGGAAAATAAATTTGCAGAAGGAATCACCAAAATCAAGAGAGATATTGTGTTTGCTGCC
AGCCTCTACTTGTAGAGTCAGCTAAAGGAATGTGAGATTTTAAATTATTGACCACCTGTTTGATTACAGTTGACTACAAATGCCTGCAAG
TGTGGATTTGGTTCTCCCATACATTTTAATATGTATTATATTTAAATCAAACATCATTCATAGAAAGCATATTACATACATGTTTATACA
TAAGCATTACATTTTTTTAATAAAAATGTATACAGGTGGGGCACTGTTTTGGTGGAAGGCTTGGAGTTTTTTTAATGAGTTTAGAGCTAT

>39593_39593_4_IL6ST-SKIV2L2_IL6ST_chr5_55251853_ENST00000381294_SKIV2L2_chr5_54639159_ENST00000545714_length(amino acids)=1204AA_BP=420
MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT
FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT
SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS
QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN
GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQERGVVWEETIILLPDNVHYVFLSATIPN
ARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIV
KMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIE
ILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADP
LNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPK
YCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSA
ISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQI
AIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENS
SEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMC

--------------------------------------------------------------
>39593_39593_5_IL6ST-SKIV2L2_IL6ST_chr5_55251853_ENST00000381298_SKIV2L2_chr5_54639159_ENST00000230640_length(transcript)=4737nt_BP=1580nt
ACTGGGGTGGCGCGCTACCTCTGCGGAGAAGGATCTGACAGTGTTCCGGAGCCGGGGCGAGCAGCCAAAAGGCCCGCGGAGTCGCGCTGG
GCCGCCCCGGCGCAGCTGAACCGGGGGCCGCGCCTGCCAGGCCGACGGGTCTGGCCCAGCCTGGCGCCAAGGGGTTCGTGCGCTGTGGAG
ACGCGGAGGGTCGAGGCGGCGCGGCCTGAGTGAAACCCAATGGAAAAAGCATGACATTTAGAAGTAGAAGACTTAGCTTCAAATCCCTAC
TCCTTCACTTACTAATTTTGTGATTTGGAAATATCCGCGCAAGATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCT
CACCACTGAATCTACAGGTGAACTTCTAGATCCATGTGGTTATATCAGTCCTGAATCTCCAGTTGTACAACTTCATTCTAATTTCACTGC
AGTTTGTGTGCTAAAGGAAAAATGTATGGATTATTTTCATGTAAATGCTAATTACATTGTCTGGAAAACAAACCATTTTACTATTCCTAA
GGAGCAATATACTATCATAAACAGAACAGCATCCAGTGTCACCTTTACAGATATAGCTTCATTAAATATTCAGCTCACTTGCAACATTCT
TACATTCGGACAGCTTGAACAGAATGTTTATGGAATCACAATAATTTCAGGCTTGCCTCCAGAAAAACCTAAAAATTTGAGTTGCATTGT
GAACGAGGGGAAGAAAATGAGGTGTGAGTGGGATGGTGGAAGGGAAACACACTTGGAGACAAACTTCACTTTAAAATCTGAATGGGCAAC
ACACAAGTTTGCTGATTGCAAAGCAAAACGTGACACCCCCACCTCATGCACTGTTGATTATTCTACTGTGTATTTTGTCAACATTGAAGT
CTGGGTAGAAGCAGAGAATGCCCTTGGGAAGGTTACATCAGATCATATCAATTTTGATCCTGTATATAAAGTGAAGCCCAATCCGCCACA
TAATTTATCAGTGATCAACTCAGAGGAACTGTCTAGTATCTTAAAATTGACATGGACCAACCCAAGTATTAAGAGTGTTATAATACTAAA
ATATAACATTCAATATAGGACCAAAGATGCCTCAACTTGGAGCCAGATTCCTCCTGAAGACACAGCATCCACCCGATCTTCATTCACTGT
CCAAGACCTTAAACCTTTTACAGAATATGTGTTTAGGATTCGCTGTATGAAGGAAGATGGTAAGGGATACTGGAGTGACTGGAGTGAAGA
AGCAAGTGGGATCACCTATGAAGATAGACCATCTAAAGCACCAAGTTTCTGGTATAAAATAGATCCATCCCATACTCAAGGCTACAGAAC
TGTACAACTCGTGTGGAAGACATTGCCTCCTTTTGAAGCCAATGGAAAAATCTTGGATTATGAAGTGACTCTCACAAGATGGAAATCACA
TTTACAAAATTACACAGTTAATGCCACAAAACTGACAGTAAATCTCACAAATGATCGCTATCTAGCAACCCTAACAGTAAGAAATCTTGT
TGGCAAATCAGATGCAGCTGTTTTAACTATCCCTGCCTGTGACTTTCAAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCC
TGATAACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTG
TCATGTTATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGA
AAATGGTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCG
GAAAGGAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTT
TAGTAAGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATT
CAGTAATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTAT
TCACCATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGAC
CTTTGCTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTC
TGGTGAATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAG
CCCAACAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACT
ACGTGTAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAA
GGTAAAGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGC
CAAATTGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAA
TGAAGGAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTA
TGTAGTAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGG
AGAGATGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGA
CAATAGACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGG
CATTCAAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAA
TTTGGAAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAAC
AGTCCTACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGG
ACGAGTGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACA
GGCAACAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCA
AATGCAGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACC
TCACTTAATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGCAGCATAAT
TCGTTGTATGAGGCGCCTGGAAGAATTGCTTCGACAAATGTGTCAAGCAGCAAAAGCCATTGGAAACACTGAGCTGGAAAATAAATTTGC
AGAAGGAATCACCAAAATCAAGAGAGATATTGTGTTTGCTGCCAGCCTCTACTTGTAGAGTCAGCTAAAGGAATGTGAGATTTTAAATTA
TTGACCACCTGTTTGATTACAGTTGACTACAAATGCCTGCAAGTGTGGATTTGGTTCTCCCATACATTTTAATATGTATTATATTTAAAT
CAAACATCATTCATAGAAAGCATATTACATACATGTTTATACATAAGCATTACATTTTTTTAATAAAAATGTATACAGGTGGGGCACTGT
TTTGGTGGAAGGCTTGGAGTTTTTTTAATGAGTTTAGAGCTATTAGATAACCACTGAGTTAAAGGTAACTATGTACACACAAAGTGTGCA
TCCAAGAGGCATAGCAGCAGCAGAAGTCTTTAAAGGCTTGTACACCAGGAAGAAAGATGCATCCTCTTGCCTTGTGGCAATCATTTTCCT
TTAGAAAACAGGCCAGCTTCACCTGGGCACCCTGCTGCCTTTCAAGGCTGGTGATTGCTCGGATAGTGATTCCCAGTTGTTGGTGTTTCA
TGCAGAGTTGTATGAGAGTCCTCCTCTTTTCTTTCTTTAAAAGAAGTTCTTTCTTTGAAGAAATCCGATACATATACAGCCTACAGTGCA
AAATATTTAATGGTATAATTTAGATCAAGTTAAAAACTACATACAAAGTTGTGATCAACAGCATCCTAAGATAAATATAAACAAAAGGAT
ATACTTTGAGGTGTACAGATTAAGCATATAAAAAATTAGAGACTAACTGGGATTTTTTAAAGATTATTCCAAATTAAGAGTTGCTTTGTT

>39593_39593_5_IL6ST-SKIV2L2_IL6ST_chr5_55251853_ENST00000381298_SKIV2L2_chr5_54639159_ENST00000230640_length(amino acids)=1204AA_BP=420
MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT
FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT
SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS
QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN
GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQERGVVWEETIILLPDNVHYVFLSATIPN
ARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIV
KMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIE
ILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADP
LNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPK
YCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSA
ISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQI
AIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENS
SEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMC

--------------------------------------------------------------
>39593_39593_6_IL6ST-SKIV2L2_IL6ST_chr5_55251853_ENST00000381298_SKIV2L2_chr5_54639159_ENST00000545714_length(transcript)=4262nt_BP=1580nt
ACTGGGGTGGCGCGCTACCTCTGCGGAGAAGGATCTGACAGTGTTCCGGAGCCGGGGCGAGCAGCCAAAAGGCCCGCGGAGTCGCGCTGG
GCCGCCCCGGCGCAGCTGAACCGGGGGCCGCGCCTGCCAGGCCGACGGGTCTGGCCCAGCCTGGCGCCAAGGGGTTCGTGCGCTGTGGAG
ACGCGGAGGGTCGAGGCGGCGCGGCCTGAGTGAAACCCAATGGAAAAAGCATGACATTTAGAAGTAGAAGACTTAGCTTCAAATCCCTAC
TCCTTCACTTACTAATTTTGTGATTTGGAAATATCCGCGCAAGATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCT
CACCACTGAATCTACAGGTGAACTTCTAGATCCATGTGGTTATATCAGTCCTGAATCTCCAGTTGTACAACTTCATTCTAATTTCACTGC
AGTTTGTGTGCTAAAGGAAAAATGTATGGATTATTTTCATGTAAATGCTAATTACATTGTCTGGAAAACAAACCATTTTACTATTCCTAA
GGAGCAATATACTATCATAAACAGAACAGCATCCAGTGTCACCTTTACAGATATAGCTTCATTAAATATTCAGCTCACTTGCAACATTCT
TACATTCGGACAGCTTGAACAGAATGTTTATGGAATCACAATAATTTCAGGCTTGCCTCCAGAAAAACCTAAAAATTTGAGTTGCATTGT
GAACGAGGGGAAGAAAATGAGGTGTGAGTGGGATGGTGGAAGGGAAACACACTTGGAGACAAACTTCACTTTAAAATCTGAATGGGCAAC
ACACAAGTTTGCTGATTGCAAAGCAAAACGTGACACCCCCACCTCATGCACTGTTGATTATTCTACTGTGTATTTTGTCAACATTGAAGT
CTGGGTAGAAGCAGAGAATGCCCTTGGGAAGGTTACATCAGATCATATCAATTTTGATCCTGTATATAAAGTGAAGCCCAATCCGCCACA
TAATTTATCAGTGATCAACTCAGAGGAACTGTCTAGTATCTTAAAATTGACATGGACCAACCCAAGTATTAAGAGTGTTATAATACTAAA
ATATAACATTCAATATAGGACCAAAGATGCCTCAACTTGGAGCCAGATTCCTCCTGAAGACACAGCATCCACCCGATCTTCATTCACTGT
CCAAGACCTTAAACCTTTTACAGAATATGTGTTTAGGATTCGCTGTATGAAGGAAGATGGTAAGGGATACTGGAGTGACTGGAGTGAAGA
AGCAAGTGGGATCACCTATGAAGATAGACCATCTAAAGCACCAAGTTTCTGGTATAAAATAGATCCATCCCATACTCAAGGCTACAGAAC
TGTACAACTCGTGTGGAAGACATTGCCTCCTTTTGAAGCCAATGGAAAAATCTTGGATTATGAAGTGACTCTCACAAGATGGAAATCACA
TTTACAAAATTACACAGTTAATGCCACAAAACTGACAGTAAATCTCACAAATGATCGCTATCTAGCAACCCTAACAGTAAGAAATCTTGT
TGGCAAATCAGATGCAGCTGTTTTAACTATCCCTGCCTGTGACTTTCAAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCC
TGATAACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTG
TCATGTTATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGA
AAATGGTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCG
GAAAGGAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTT
TAGTAAGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATT
CAGTAATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTAT
TCACCATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGAC
CTTTGCTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTC
TGGTGAATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAG
CCCAACAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACT
ACGTGTAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAA
GGTAAAGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGC
CAAATTGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAA
TGAAGGAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTA
TGTAGTAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGG
AGAGATGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGA
CAATAGACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGG
CATTCAAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAA
TTTGGAAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAAC
AGTCCTACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGG
ACGAGTGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACA
GGCAACAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCA
AATGCAGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACC
TCACTTAATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGCAGCATAAT
TCGTTGTATGAGGCGCCTGGAAGAATTGCTTCGACAAATGTGTCAAGCAGCAAAAGCCATTGGAAACACTGAGCTGGAAAATAAATTTGC
AGAAGGAATCACCAAAATCAAGAGAGATATTGTGTTTGCTGCCAGCCTCTACTTGTAGAGTCAGCTAAAGGAATGTGAGATTTTAAATTA
TTGACCACCTGTTTGATTACAGTTGACTACAAATGCCTGCAAGTGTGGATTTGGTTCTCCCATACATTTTAATATGTATTATATTTAAAT
CAAACATCATTCATAGAAAGCATATTACATACATGTTTATACATAAGCATTACATTTTTTTAATAAAAATGTATACAGGTGGGGCACTGT
TTTGGTGGAAGGCTTGGAGTTTTTTTAATGAGTTTAGAGCTATTAGATAACCACTGAGTTAAAGGTAACTATGTACACACAAAGTGTGCA

>39593_39593_6_IL6ST-SKIV2L2_IL6ST_chr5_55251853_ENST00000381298_SKIV2L2_chr5_54639159_ENST00000545714_length(amino acids)=1204AA_BP=420
MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT
FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT
SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS
QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN
GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQERGVVWEETIILLPDNVHYVFLSATIPN
ARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIV
KMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIE
ILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADP
LNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPK
YCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSA
ISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQI
AIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENS
SEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMC

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Fusion Gene PPI Analysis for IL6ST-SKIV2L2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for IL6ST-SKIV2L2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for IL6ST-SKIV2L2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource