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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:IL6ST-YTHDC2 (FusionGDB2 ID:39595)

Fusion Gene Summary for IL6ST-YTHDC2

check button Fusion gene summary
Fusion gene informationFusion gene name: IL6ST-YTHDC2
Fusion gene ID: 39595
HgeneTgene
Gene symbol

IL6ST

YTHDC2

Gene ID

3572

64848

Gene nameinterleukin 6 signal transducerYTH domain containing 2
SynonymsCD130|CDW130|GP130|HIES4|IL-6RB|sGP130CAHL|hYTHDC2
Cytomap

5q11.2

5q22.2

Type of geneprotein-codingprotein-coding
Descriptioninterleukin-6 receptor subunit betaCD130 antigenIL-6 receptor subunit betaIL-6R subunit betagp130 of the rheumatoid arthritis antigenic peptide-bearing soluble formgp130, oncostatin M receptorinterleukin receptor beta chainmembrane glycoprotein 1303'-5' RNA helicase YTHDC2CsA-associated helicase-like proteinprobable ATP-dependent RNA helicase YTHDC2
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000336909, ENST00000381286, 
ENST00000381287, ENST00000381293, 
ENST00000381294, ENST00000381298, 
ENST00000396816, ENST00000502326, 
ENST00000522633, ENST00000536319, 
ENST00000577363, 		ENST00000515883, 
ENST00000161863, 
Fusion gene scores* DoF score16 X 11 X 5=8804 X 4 X 2=32
# samples 194
** MAII scorelog2(19/880*10)=-2.21150410519371
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: IL6ST [Title/Abstract] AND YTHDC2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointIL6ST(55272042)-YTHDC2(112926737), # samples:2
Anticipated loss of major functional domain due to fusion event.IL6ST-YTHDC2 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
IL6ST-YTHDC2 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
IL6ST-YTHDC2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneIL6ST

GO:0008284

positive regulation of cell proliferation

2261637

HgeneIL6ST

GO:0019221

cytokine-mediated signaling pathway

2261637

HgeneIL6ST

GO:0034097

response to cytokine

2261637|8999038

HgeneIL6ST

GO:0048861

leukemia inhibitory factor signaling pathway

8999038|12643274

HgeneIL6ST

GO:0070120

ciliary neurotrophic factor-mediated signaling pathway

12643274

TgeneYTHDC2

GO:0034612

response to tumor necrosis factor

21559518

TgeneYTHDC2

GO:0070555

response to interleukin-1

21559518


check buttonFusion gene breakpoints across IL6ST (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across YTHDC2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-G9-6329IL6STchr5

55272042

-YTHDC2chr5

112926737

+


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Fusion Gene ORF analysis for IL6ST-YTHDC2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000336909ENST00000515883IL6STchr5

55272042

-YTHDC2chr5

112926737

+
5CDS-intronENST00000381286ENST00000515883IL6STchr5

55272042

-YTHDC2chr5

112926737

+
5CDS-intronENST00000381287ENST00000515883IL6STchr5

55272042

-YTHDC2chr5

112926737

+
5CDS-intronENST00000381293ENST00000515883IL6STchr5

55272042

-YTHDC2chr5

112926737

+
5CDS-intronENST00000381294ENST00000515883IL6STchr5

55272042

-YTHDC2chr5

112926737

+
5CDS-intronENST00000381298ENST00000515883IL6STchr5

55272042

-YTHDC2chr5

112926737

+
5CDS-intronENST00000396816ENST00000515883IL6STchr5

55272042

-YTHDC2chr5

112926737

+
5CDS-intronENST00000502326ENST00000515883IL6STchr5

55272042

-YTHDC2chr5

112926737

+
5CDS-intronENST00000522633ENST00000515883IL6STchr5

55272042

-YTHDC2chr5

112926737

+
5CDS-intronENST00000536319ENST00000515883IL6STchr5

55272042

-YTHDC2chr5

112926737

+
5UTR-3CDSENST00000577363ENST00000161863IL6STchr5

55272042

-YTHDC2chr5

112926737

+
5UTR-intronENST00000577363ENST00000515883IL6STchr5

55272042

-YTHDC2chr5

112926737

+
Frame-shiftENST00000381298ENST00000161863IL6STchr5

55272042

-YTHDC2chr5

112926737

+
In-frameENST00000336909ENST00000161863IL6STchr5

55272042

-YTHDC2chr5

112926737

+
In-frameENST00000381286ENST00000161863IL6STchr5

55272042

-YTHDC2chr5

112926737

+
In-frameENST00000381287ENST00000161863IL6STchr5

55272042

-YTHDC2chr5

112926737

+
In-frameENST00000381293ENST00000161863IL6STchr5

55272042

-YTHDC2chr5

112926737

+
In-frameENST00000381294ENST00000161863IL6STchr5

55272042

-YTHDC2chr5

112926737

+
In-frameENST00000396816ENST00000161863IL6STchr5

55272042

-YTHDC2chr5

112926737

+
In-frameENST00000502326ENST00000161863IL6STchr5

55272042

-YTHDC2chr5

112926737

+
In-frameENST00000522633ENST00000161863IL6STchr5

55272042

-YTHDC2chr5

112926737

+
In-frameENST00000536319ENST00000161863IL6STchr5

55272042

-YTHDC2chr5

112926737

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000336909IL6STchr555272042-ENST00000161863YTHDC2chr5112926737+237810088567159
ENST00000381287IL6STchr555272042-ENST00000161863YTHDC2chr5112926737+237810088567159
ENST00000502326IL6STchr555272042-ENST00000161863YTHDC2chr5112926737+2538260248727159
ENST00000381294IL6STchr555272042-ENST00000161863YTHDC2chr5112926737+23426452531159
ENST00000536319IL6STchr555272042-ENST00000161863YTHDC2chr5112926737+23426452531159
ENST00000381293IL6STchr555272042-ENST00000161863YTHDC2chr5112926737+23426452531159
ENST00000381286IL6STchr555272042-ENST00000161863YTHDC2chr5112926737+23426452531159
ENST00000522633IL6STchr555272042-ENST00000161863YTHDC2chr5112926737+2434156144623159
ENST00000396816IL6STchr555272042-ENST00000161863YTHDC2chr5112926737+23426452531159

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000336909ENST00000161863IL6STchr555272042-YTHDC2chr5112926737+0.032680430.9673196
ENST00000381287ENST00000161863IL6STchr555272042-YTHDC2chr5112926737+0.032680430.9673196
ENST00000502326ENST00000161863IL6STchr555272042-YTHDC2chr5112926737+0.0197980.980202
ENST00000381294ENST00000161863IL6STchr555272042-YTHDC2chr5112926737+0.0347527640.9652473
ENST00000536319ENST00000161863IL6STchr555272042-YTHDC2chr5112926737+0.0347527640.9652473
ENST00000381293ENST00000161863IL6STchr555272042-YTHDC2chr5112926737+0.0347527640.9652473
ENST00000381286ENST00000161863IL6STchr555272042-YTHDC2chr5112926737+0.0347527640.9652473
ENST00000522633ENST00000161863IL6STchr555272042-YTHDC2chr5112926737+0.0417210050.958279
ENST00000396816ENST00000161863IL6STchr555272042-YTHDC2chr5112926737+0.0347527640.9652473

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Fusion Genomic Features for IL6ST-YTHDC2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
IL6STchr555272042-YTHDC2chr5112926737+8.06E-080.9999999
IL6STchr555272042-YTHDC2chr5112926737+8.06E-080.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for IL6ST-YTHDC2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:55272042/chr5:112926737)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneYTHDC2chr5:55272042chr5:112926737ENST0000016186325301288_141812751898.6666666666667DomainYTH
TgeneYTHDC2chr5:55272042chr5:112926737ENST0000016186325301294_129612751898.6666666666667RegionN6-methyladenosine binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIL6STchr5:55272042chr5:112926737ENST00000336909-115725_75521919.0Compositional biasNote=Ser-rich
HgeneIL6STchr5:55272042chr5:112926737ENST00000381287-114725_755212415.0Compositional biasNote=Ser-rich
HgeneIL6STchr5:55272042chr5:112926737ENST00000381294-114725_75521858.0Compositional biasNote=Ser-rich
HgeneIL6STchr5:55272042chr5:112926737ENST00000381298-317725_75521919.0Compositional biasNote=Ser-rich
HgeneIL6STchr5:55272042chr5:112926737ENST00000502326-216725_75521919.0Compositional biasNote=Ser-rich
HgeneIL6STchr5:55272042chr5:112926737ENST00000522633-213725_75521299.3333333333333Compositional biasNote=Ser-rich
HgeneIL6STchr5:55272042chr5:112926737ENST00000536319-113725_75521441.3333333333333Compositional biasNote=Ser-rich
HgeneIL6STchr5:55272042chr5:112926737ENST00000336909-115125_21621919.0DomainFibronectin type-III 1
HgeneIL6STchr5:55272042chr5:112926737ENST00000336909-115224_32421919.0DomainFibronectin type-III 2
HgeneIL6STchr5:55272042chr5:112926737ENST00000336909-11526_12021919.0DomainNote=Ig-like C2-type
HgeneIL6STchr5:55272042chr5:112926737ENST00000336909-115329_42421919.0DomainFibronectin type-III 3
HgeneIL6STchr5:55272042chr5:112926737ENST00000336909-115426_51721919.0DomainFibronectin type-III 4
HgeneIL6STchr5:55272042chr5:112926737ENST00000336909-115518_61321919.0DomainFibronectin type-III 5
HgeneIL6STchr5:55272042chr5:112926737ENST00000381287-114125_216212415.0DomainFibronectin type-III 1
HgeneIL6STchr5:55272042chr5:112926737ENST00000381287-114224_324212415.0DomainFibronectin type-III 2
HgeneIL6STchr5:55272042chr5:112926737ENST00000381287-11426_120212415.0DomainNote=Ig-like C2-type
HgeneIL6STchr5:55272042chr5:112926737ENST00000381287-114329_424212415.0DomainFibronectin type-III 3
HgeneIL6STchr5:55272042chr5:112926737ENST00000381287-114426_517212415.0DomainFibronectin type-III 4
HgeneIL6STchr5:55272042chr5:112926737ENST00000381287-114518_613212415.0DomainFibronectin type-III 5
HgeneIL6STchr5:55272042chr5:112926737ENST00000381294-114125_21621858.0DomainFibronectin type-III 1
HgeneIL6STchr5:55272042chr5:112926737ENST00000381294-114224_32421858.0DomainFibronectin type-III 2
HgeneIL6STchr5:55272042chr5:112926737ENST00000381294-11426_12021858.0DomainNote=Ig-like C2-type
HgeneIL6STchr5:55272042chr5:112926737ENST00000381294-114329_42421858.0DomainFibronectin type-III 3
HgeneIL6STchr5:55272042chr5:112926737ENST00000381294-114426_51721858.0DomainFibronectin type-III 4
HgeneIL6STchr5:55272042chr5:112926737ENST00000381294-114518_61321858.0DomainFibronectin type-III 5
HgeneIL6STchr5:55272042chr5:112926737ENST00000381298-317125_21621919.0DomainFibronectin type-III 1
HgeneIL6STchr5:55272042chr5:112926737ENST00000381298-317224_32421919.0DomainFibronectin type-III 2
HgeneIL6STchr5:55272042chr5:112926737ENST00000381298-31726_12021919.0DomainNote=Ig-like C2-type
HgeneIL6STchr5:55272042chr5:112926737ENST00000381298-317329_42421919.0DomainFibronectin type-III 3
HgeneIL6STchr5:55272042chr5:112926737ENST00000381298-317426_51721919.0DomainFibronectin type-III 4
HgeneIL6STchr5:55272042chr5:112926737ENST00000381298-317518_61321919.0DomainFibronectin type-III 5
HgeneIL6STchr5:55272042chr5:112926737ENST00000502326-216125_21621919.0DomainFibronectin type-III 1
HgeneIL6STchr5:55272042chr5:112926737ENST00000502326-216224_32421919.0DomainFibronectin type-III 2
HgeneIL6STchr5:55272042chr5:112926737ENST00000502326-21626_12021919.0DomainNote=Ig-like C2-type
HgeneIL6STchr5:55272042chr5:112926737ENST00000502326-216329_42421919.0DomainFibronectin type-III 3
HgeneIL6STchr5:55272042chr5:112926737ENST00000502326-216426_51721919.0DomainFibronectin type-III 4
HgeneIL6STchr5:55272042chr5:112926737ENST00000502326-216518_61321919.0DomainFibronectin type-III 5
HgeneIL6STchr5:55272042chr5:112926737ENST00000522633-213125_21621299.3333333333333DomainFibronectin type-III 1
HgeneIL6STchr5:55272042chr5:112926737ENST00000522633-213224_32421299.3333333333333DomainFibronectin type-III 2
HgeneIL6STchr5:55272042chr5:112926737ENST00000522633-21326_12021299.3333333333333DomainNote=Ig-like C2-type
HgeneIL6STchr5:55272042chr5:112926737ENST00000522633-213329_42421299.3333333333333DomainFibronectin type-III 3
HgeneIL6STchr5:55272042chr5:112926737ENST00000522633-213426_51721299.3333333333333DomainFibronectin type-III 4
HgeneIL6STchr5:55272042chr5:112926737ENST00000522633-213518_61321299.3333333333333DomainFibronectin type-III 5
HgeneIL6STchr5:55272042chr5:112926737ENST00000536319-113125_21621441.3333333333333DomainFibronectin type-III 1
HgeneIL6STchr5:55272042chr5:112926737ENST00000536319-113224_32421441.3333333333333DomainFibronectin type-III 2
HgeneIL6STchr5:55272042chr5:112926737ENST00000536319-11326_12021441.3333333333333DomainNote=Ig-like C2-type
HgeneIL6STchr5:55272042chr5:112926737ENST00000536319-113329_42421441.3333333333333DomainFibronectin type-III 3
HgeneIL6STchr5:55272042chr5:112926737ENST00000536319-113426_51721441.3333333333333DomainFibronectin type-III 4
HgeneIL6STchr5:55272042chr5:112926737ENST00000536319-113518_61321441.3333333333333DomainFibronectin type-III 5
HgeneIL6STchr5:55272042chr5:112926737ENST00000336909-115310_31421919.0MotifNote=WSXWS motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000336909-115651_65921919.0MotifNote=Box 1 motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000381287-114310_314212415.0MotifNote=WSXWS motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000381287-114651_659212415.0MotifNote=Box 1 motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000381294-114310_31421858.0MotifNote=WSXWS motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000381294-114651_65921858.0MotifNote=Box 1 motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000381298-317310_31421919.0MotifNote=WSXWS motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000381298-317651_65921919.0MotifNote=Box 1 motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000502326-216310_31421919.0MotifNote=WSXWS motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000502326-216651_65921919.0MotifNote=Box 1 motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000522633-213310_31421299.3333333333333MotifNote=WSXWS motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000522633-213651_65921299.3333333333333MotifNote=Box 1 motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000536319-113310_31421441.3333333333333MotifNote=WSXWS motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000536319-113651_65921441.3333333333333MotifNote=Box 1 motif
HgeneIL6STchr5:55272042chr5:112926737ENST00000336909-11523_61921919.0Topological domainExtracellular
HgeneIL6STchr5:55272042chr5:112926737ENST00000336909-115642_91821919.0Topological domainCytoplasmic
HgeneIL6STchr5:55272042chr5:112926737ENST00000381287-11423_619212415.0Topological domainExtracellular
HgeneIL6STchr5:55272042chr5:112926737ENST00000381287-114642_918212415.0Topological domainCytoplasmic
HgeneIL6STchr5:55272042chr5:112926737ENST00000381294-11423_61921858.0Topological domainExtracellular
HgeneIL6STchr5:55272042chr5:112926737ENST00000381294-114642_91821858.0Topological domainCytoplasmic
HgeneIL6STchr5:55272042chr5:112926737ENST00000381298-31723_61921919.0Topological domainExtracellular
HgeneIL6STchr5:55272042chr5:112926737ENST00000381298-317642_91821919.0Topological domainCytoplasmic
HgeneIL6STchr5:55272042chr5:112926737ENST00000502326-21623_61921919.0Topological domainExtracellular
HgeneIL6STchr5:55272042chr5:112926737ENST00000502326-216642_91821919.0Topological domainCytoplasmic
HgeneIL6STchr5:55272042chr5:112926737ENST00000522633-21323_61921299.3333333333333Topological domainExtracellular
HgeneIL6STchr5:55272042chr5:112926737ENST00000522633-213642_91821299.3333333333333Topological domainCytoplasmic
HgeneIL6STchr5:55272042chr5:112926737ENST00000536319-11323_61921441.3333333333333Topological domainExtracellular
HgeneIL6STchr5:55272042chr5:112926737ENST00000536319-113642_91821441.3333333333333Topological domainCytoplasmic
HgeneIL6STchr5:55272042chr5:112926737ENST00000336909-115620_64121919.0TransmembraneHelical
HgeneIL6STchr5:55272042chr5:112926737ENST00000381287-114620_641212415.0TransmembraneHelical
HgeneIL6STchr5:55272042chr5:112926737ENST00000381294-114620_64121858.0TransmembraneHelical
HgeneIL6STchr5:55272042chr5:112926737ENST00000381298-317620_64121919.0TransmembraneHelical
HgeneIL6STchr5:55272042chr5:112926737ENST00000502326-216620_64121919.0TransmembraneHelical
HgeneIL6STchr5:55272042chr5:112926737ENST00000522633-213620_64121299.3333333333333TransmembraneHelical
HgeneIL6STchr5:55272042chr5:112926737ENST00000536319-113620_64121441.3333333333333TransmembraneHelical
TgeneYTHDC2chr5:55272042chr5:112926737ENST0000016186325301248_128112751898.6666666666667Compositional biasNote=Ser-rich
TgeneYTHDC2chr5:55272042chr5:112926737ENST00000161863253015_3112751898.6666666666667Compositional biasNote=Gly-rich
TgeneYTHDC2chr5:55272042chr5:112926737ENST000001618632530203_36912751898.6666666666667DomainHelicase ATP-binding
TgeneYTHDC2chr5:55272042chr5:112926737ENST00000161863253038_10612751898.6666666666667DomainR3H
TgeneYTHDC2chr5:55272042chr5:112926737ENST000001618632530612_78412751898.6666666666667DomainHelicase C-terminal
TgeneYTHDC2chr5:55272042chr5:112926737ENST000001618632530316_31912751898.6666666666667MotifNote=DEAH box
TgeneYTHDC2chr5:55272042chr5:112926737ENST000001618632530216_22312751898.6666666666667Nucleotide bindingATP
TgeneYTHDC2chr5:55272042chr5:112926737ENST000001618632530506_53812751898.6666666666667RepeatNote=ANK 1
TgeneYTHDC2chr5:55272042chr5:112926737ENST000001618632530539_57112751898.6666666666667RepeatNote=ANK 2


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Fusion Gene Sequence for IL6ST-YTHDC2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>39595_39595_1_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000336909_YTHDC2_chr5_112926737_ENST00000161863_length(transcript)=2378nt_BP=100nt
TATTACATGTGTCTGTTGCAGAAATATCCGCGCAAGATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACT
GAATCTACAGGGCTCAAAATCTCCTTCGCCAAGACCAAACATGCCTGTTCGATACTTCATAATGAAGAGTAGCAATTTGAGAAACCTTGA
AATTTCTCAACAGAAGGGTATCTGGTCTACAACTCCTAGTAATGAACGGAAGCTAAATCGAGCCTTTTGGGAAAGCAGCATAGTTTACTT
GGTATTTTCTGTTCAAGGATCTGGACATTTCCAGGGATTTTCTAGGATGTCTTCTGAGATTGGAAGGGAAAAGAGTCAGGACTGGGGCTC
TGCTGGACTAGGAGGAGTATTTAAGGTGGAGTGGATACGAAAAGAAAGCCTTCCCTTTCAATTTGCACACCATTTACTCAATCCATGGAA
TGACAACAAGAAAGTGCAGATAAGCAGGGATGGGCAGGAACTAGAACCTCTGGTTGGTGAACAGTTGCTCCAGTTATGGGAACGTCTTCC
CTTGGGAGAAAAAAACACAACTGATTGACACTCAGAACTCTTAGCTGTGGAAGAACATCATGCCTATTTATAACCACTGAATGCACTGAC
TTTCAAAAACTGAGGTGGGGTGTGTGTTACGAATGGGCTTTTTAACACTTTTAGAGTGTTGCTTTAGAACTACCATCTTCATATACAGGA
GAAAGGAAGCATTTAAATTTTTATAGTGATTATAGAGAATGATTATATGATGTTTGTAATGAATAAAATAGTAGTTTCATTATTTGGCAC
AATAGCAGTTTATTTTAAACAAACAATTTGAAGTTAAACATTTCATTTTTAAAAACACTGAATTACAGTTCTTATTGATGACTTTTTAAT
GCAGAGTAAGTTGTTTAAGAAAGGCCTGAATATATCAGAACATCTGAGCACCATTTTAGAAGAGTCAACTCTTAAGATTATCATTAGAAA
ACAAATACGTCAACACCTATGAAAAGAAGCGGGGAAAACAACAACAAGGACAACAACAAAAAACCAGTGAAATTCTACAAGTGTCCCTTT
TAAAAATAGTGTGTGCTAACTAAGGGCTATTCATTCTGCCATTTTTAACTTGAGACACATTTAAGAATAAAGTTGGATGTTCTTTTTCTG
TGATTATGAAATGCAATAAAATCTGAATAAAGGGCAAAGTTTCTTCCTGATCAGATTAGATTAAGTGCTTAGTTTTATTCCTAATTCTGC
CCCTTTTAACCTGATGTGTACCTTACTCTTTCCTCCCTCTCTTCCTCCCTTCCTCCTCTCCCCGCTCCTTTCCTGCATTTCTCCCTCCCT
CCTTCCCTCGTCACATCTCTTATATGAGCACAGTAATTATGACCTTTTTGTTTTGGCTACAACTTGATTGAAACAAGTTCAAAATTTAAA
CAAGTTCATACAAGTTTTTAAAAATTCTCAACTGGTAGCTTGCTTGCTGTGCGTCTTCCAAACTAAAGCCTGCAAGCGCCACAATTCTAA
GTGCCGCCTTCCATTTTTTTTCAGTATGTTTTCACTGGCTTATGTTTTCAGATATGATTTTCCTTTTTCGCATATATGGTTTAATAAATG
GGGGATAATTTTTTTTTTGTAAATCCGTGCTTGTGCCAAGTCTCATATTTCTTTGCCATCTCAGAATTATCTTTTTACCACCACTGTTTA
TAAAATTTCCTTAGAGACTTTTTGAAGGGAAAATAGAGCAACAGGGAAAAATGAAAGAAATGTCTTGGTTACTGAGCTCTAAATAGACAG
GTTTGATGGCACTTCTCATGATACATTTTAGTTATTCTTATAAAAGCAAACAGGCAAACATGAGTGTAAATTAAAGACAAAAAGAAAACT
CTGGTTTTATATTTGAGAACACGTGAAAAATCATGGGTCAACATAAAATCTTGAGAACCTTCTACTTTCTCTGGGAAAGCATTATATAGT
GGTGCATTAGTTTAGAAAGTCAGCTATGATTTTGCCTATAGTTCTAGTTATTAGCTTTGGGGTTTTCTTGTACTTTAAGACATACCTGTA
AATTGAACCTATTTGAATTATATTCCACTGTATGTGTATTATGGCTCTTTTCCTATTAGAGCAACTTGTGTTTCCCTGATAATGTGTACA
TTTTTTAGGCATGTACTTAATAGTTCACAATGTTCTAAATTTGGAAGGACTTAAAAAAAAAACTTGTTTAAATTTCCATCTGTTTTGTAA
TATCTAGCTCTATATGTAAATGATGGGTTTGTTGGTATTTAAAATGAATACAACTTGAATGTAATTAAAGTGCTGTTTTTTGGAAGCGAT

>39595_39595_1_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000336909_YTHDC2_chr5_112926737_ENST00000161863_length(amino acids)=159AA_BP=2
MNLQGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWG

--------------------------------------------------------------
>39595_39595_2_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000381286_YTHDC2_chr5_112926737_ENST00000161863_length(transcript)=2342nt_BP=64nt
ATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACTGAATCTACAGGGCTCAAAATCTCCTTCGCCAAGACC
AAACATGCCTGTTCGATACTTCATAATGAAGAGTAGCAATTTGAGAAACCTTGAAATTTCTCAACAGAAGGGTATCTGGTCTACAACTCC
TAGTAATGAACGGAAGCTAAATCGAGCCTTTTGGGAAAGCAGCATAGTTTACTTGGTATTTTCTGTTCAAGGATCTGGACATTTCCAGGG
ATTTTCTAGGATGTCTTCTGAGATTGGAAGGGAAAAGAGTCAGGACTGGGGCTCTGCTGGACTAGGAGGAGTATTTAAGGTGGAGTGGAT
ACGAAAAGAAAGCCTTCCCTTTCAATTTGCACACCATTTACTCAATCCATGGAATGACAACAAGAAAGTGCAGATAAGCAGGGATGGGCA
GGAACTAGAACCTCTGGTTGGTGAACAGTTGCTCCAGTTATGGGAACGTCTTCCCTTGGGAGAAAAAAACACAACTGATTGACACTCAGA
ACTCTTAGCTGTGGAAGAACATCATGCCTATTTATAACCACTGAATGCACTGACTTTCAAAAACTGAGGTGGGGTGTGTGTTACGAATGG
GCTTTTTAACACTTTTAGAGTGTTGCTTTAGAACTACCATCTTCATATACAGGAGAAAGGAAGCATTTAAATTTTTATAGTGATTATAGA
GAATGATTATATGATGTTTGTAATGAATAAAATAGTAGTTTCATTATTTGGCACAATAGCAGTTTATTTTAAACAAACAATTTGAAGTTA
AACATTTCATTTTTAAAAACACTGAATTACAGTTCTTATTGATGACTTTTTAATGCAGAGTAAGTTGTTTAAGAAAGGCCTGAATATATC
AGAACATCTGAGCACCATTTTAGAAGAGTCAACTCTTAAGATTATCATTAGAAAACAAATACGTCAACACCTATGAAAAGAAGCGGGGAA
AACAACAACAAGGACAACAACAAAAAACCAGTGAAATTCTACAAGTGTCCCTTTTAAAAATAGTGTGTGCTAACTAAGGGCTATTCATTC
TGCCATTTTTAACTTGAGACACATTTAAGAATAAAGTTGGATGTTCTTTTTCTGTGATTATGAAATGCAATAAAATCTGAATAAAGGGCA
AAGTTTCTTCCTGATCAGATTAGATTAAGTGCTTAGTTTTATTCCTAATTCTGCCCCTTTTAACCTGATGTGTACCTTACTCTTTCCTCC
CTCTCTTCCTCCCTTCCTCCTCTCCCCGCTCCTTTCCTGCATTTCTCCCTCCCTCCTTCCCTCGTCACATCTCTTATATGAGCACAGTAA
TTATGACCTTTTTGTTTTGGCTACAACTTGATTGAAACAAGTTCAAAATTTAAACAAGTTCATACAAGTTTTTAAAAATTCTCAACTGGT
AGCTTGCTTGCTGTGCGTCTTCCAAACTAAAGCCTGCAAGCGCCACAATTCTAAGTGCCGCCTTCCATTTTTTTTCAGTATGTTTTCACT
GGCTTATGTTTTCAGATATGATTTTCCTTTTTCGCATATATGGTTTAATAAATGGGGGATAATTTTTTTTTTGTAAATCCGTGCTTGTGC
CAAGTCTCATATTTCTTTGCCATCTCAGAATTATCTTTTTACCACCACTGTTTATAAAATTTCCTTAGAGACTTTTTGAAGGGAAAATAG
AGCAACAGGGAAAAATGAAAGAAATGTCTTGGTTACTGAGCTCTAAATAGACAGGTTTGATGGCACTTCTCATGATACATTTTAGTTATT
CTTATAAAAGCAAACAGGCAAACATGAGTGTAAATTAAAGACAAAAAGAAAACTCTGGTTTTATATTTGAGAACACGTGAAAAATCATGG
GTCAACATAAAATCTTGAGAACCTTCTACTTTCTCTGGGAAAGCATTATATAGTGGTGCATTAGTTTAGAAAGTCAGCTATGATTTTGCC
TATAGTTCTAGTTATTAGCTTTGGGGTTTTCTTGTACTTTAAGACATACCTGTAAATTGAACCTATTTGAATTATATTCCACTGTATGTG
TATTATGGCTCTTTTCCTATTAGAGCAACTTGTGTTTCCCTGATAATGTGTACATTTTTTAGGCATGTACTTAATAGTTCACAATGTTCT
AAATTTGGAAGGACTTAAAAAAAAAACTTGTTTAAATTTCCATCTGTTTTGTAATATCTAGCTCTATATGTAAATGATGGGTTTGTTGGT
ATTTAAAATGAATACAACTTGAATGTAATTAAAGTGCTGTTTTTTGGAAGCGATAAACTTTAAATATACTTATTAAAATGAAATTCTATT

>39595_39595_2_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000381286_YTHDC2_chr5_112926737_ENST00000161863_length(amino acids)=159AA_BP=2
MNLQGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWG

--------------------------------------------------------------
>39595_39595_3_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000381287_YTHDC2_chr5_112926737_ENST00000161863_length(transcript)=2378nt_BP=100nt
TATTACATGTGTCTGTTGCAGAAATATCCGCGCAAGATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACT
GAATCTACAGGGCTCAAAATCTCCTTCGCCAAGACCAAACATGCCTGTTCGATACTTCATAATGAAGAGTAGCAATTTGAGAAACCTTGA
AATTTCTCAACAGAAGGGTATCTGGTCTACAACTCCTAGTAATGAACGGAAGCTAAATCGAGCCTTTTGGGAAAGCAGCATAGTTTACTT
GGTATTTTCTGTTCAAGGATCTGGACATTTCCAGGGATTTTCTAGGATGTCTTCTGAGATTGGAAGGGAAAAGAGTCAGGACTGGGGCTC
TGCTGGACTAGGAGGAGTATTTAAGGTGGAGTGGATACGAAAAGAAAGCCTTCCCTTTCAATTTGCACACCATTTACTCAATCCATGGAA
TGACAACAAGAAAGTGCAGATAAGCAGGGATGGGCAGGAACTAGAACCTCTGGTTGGTGAACAGTTGCTCCAGTTATGGGAACGTCTTCC
CTTGGGAGAAAAAAACACAACTGATTGACACTCAGAACTCTTAGCTGTGGAAGAACATCATGCCTATTTATAACCACTGAATGCACTGAC
TTTCAAAAACTGAGGTGGGGTGTGTGTTACGAATGGGCTTTTTAACACTTTTAGAGTGTTGCTTTAGAACTACCATCTTCATATACAGGA
GAAAGGAAGCATTTAAATTTTTATAGTGATTATAGAGAATGATTATATGATGTTTGTAATGAATAAAATAGTAGTTTCATTATTTGGCAC
AATAGCAGTTTATTTTAAACAAACAATTTGAAGTTAAACATTTCATTTTTAAAAACACTGAATTACAGTTCTTATTGATGACTTTTTAAT
GCAGAGTAAGTTGTTTAAGAAAGGCCTGAATATATCAGAACATCTGAGCACCATTTTAGAAGAGTCAACTCTTAAGATTATCATTAGAAA
ACAAATACGTCAACACCTATGAAAAGAAGCGGGGAAAACAACAACAAGGACAACAACAAAAAACCAGTGAAATTCTACAAGTGTCCCTTT
TAAAAATAGTGTGTGCTAACTAAGGGCTATTCATTCTGCCATTTTTAACTTGAGACACATTTAAGAATAAAGTTGGATGTTCTTTTTCTG
TGATTATGAAATGCAATAAAATCTGAATAAAGGGCAAAGTTTCTTCCTGATCAGATTAGATTAAGTGCTTAGTTTTATTCCTAATTCTGC
CCCTTTTAACCTGATGTGTACCTTACTCTTTCCTCCCTCTCTTCCTCCCTTCCTCCTCTCCCCGCTCCTTTCCTGCATTTCTCCCTCCCT
CCTTCCCTCGTCACATCTCTTATATGAGCACAGTAATTATGACCTTTTTGTTTTGGCTACAACTTGATTGAAACAAGTTCAAAATTTAAA
CAAGTTCATACAAGTTTTTAAAAATTCTCAACTGGTAGCTTGCTTGCTGTGCGTCTTCCAAACTAAAGCCTGCAAGCGCCACAATTCTAA
GTGCCGCCTTCCATTTTTTTTCAGTATGTTTTCACTGGCTTATGTTTTCAGATATGATTTTCCTTTTTCGCATATATGGTTTAATAAATG
GGGGATAATTTTTTTTTTGTAAATCCGTGCTTGTGCCAAGTCTCATATTTCTTTGCCATCTCAGAATTATCTTTTTACCACCACTGTTTA
TAAAATTTCCTTAGAGACTTTTTGAAGGGAAAATAGAGCAACAGGGAAAAATGAAAGAAATGTCTTGGTTACTGAGCTCTAAATAGACAG
GTTTGATGGCACTTCTCATGATACATTTTAGTTATTCTTATAAAAGCAAACAGGCAAACATGAGTGTAAATTAAAGACAAAAAGAAAACT
CTGGTTTTATATTTGAGAACACGTGAAAAATCATGGGTCAACATAAAATCTTGAGAACCTTCTACTTTCTCTGGGAAAGCATTATATAGT
GGTGCATTAGTTTAGAAAGTCAGCTATGATTTTGCCTATAGTTCTAGTTATTAGCTTTGGGGTTTTCTTGTACTTTAAGACATACCTGTA
AATTGAACCTATTTGAATTATATTCCACTGTATGTGTATTATGGCTCTTTTCCTATTAGAGCAACTTGTGTTTCCCTGATAATGTGTACA
TTTTTTAGGCATGTACTTAATAGTTCACAATGTTCTAAATTTGGAAGGACTTAAAAAAAAAACTTGTTTAAATTTCCATCTGTTTTGTAA
TATCTAGCTCTATATGTAAATGATGGGTTTGTTGGTATTTAAAATGAATACAACTTGAATGTAATTAAAGTGCTGTTTTTTGGAAGCGAT

>39595_39595_3_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000381287_YTHDC2_chr5_112926737_ENST00000161863_length(amino acids)=159AA_BP=2
MNLQGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWG

--------------------------------------------------------------
>39595_39595_4_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000381293_YTHDC2_chr5_112926737_ENST00000161863_length(transcript)=2342nt_BP=64nt
ATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACTGAATCTACAGGGCTCAAAATCTCCTTCGCCAAGACC
AAACATGCCTGTTCGATACTTCATAATGAAGAGTAGCAATTTGAGAAACCTTGAAATTTCTCAACAGAAGGGTATCTGGTCTACAACTCC
TAGTAATGAACGGAAGCTAAATCGAGCCTTTTGGGAAAGCAGCATAGTTTACTTGGTATTTTCTGTTCAAGGATCTGGACATTTCCAGGG
ATTTTCTAGGATGTCTTCTGAGATTGGAAGGGAAAAGAGTCAGGACTGGGGCTCTGCTGGACTAGGAGGAGTATTTAAGGTGGAGTGGAT
ACGAAAAGAAAGCCTTCCCTTTCAATTTGCACACCATTTACTCAATCCATGGAATGACAACAAGAAAGTGCAGATAAGCAGGGATGGGCA
GGAACTAGAACCTCTGGTTGGTGAACAGTTGCTCCAGTTATGGGAACGTCTTCCCTTGGGAGAAAAAAACACAACTGATTGACACTCAGA
ACTCTTAGCTGTGGAAGAACATCATGCCTATTTATAACCACTGAATGCACTGACTTTCAAAAACTGAGGTGGGGTGTGTGTTACGAATGG
GCTTTTTAACACTTTTAGAGTGTTGCTTTAGAACTACCATCTTCATATACAGGAGAAAGGAAGCATTTAAATTTTTATAGTGATTATAGA
GAATGATTATATGATGTTTGTAATGAATAAAATAGTAGTTTCATTATTTGGCACAATAGCAGTTTATTTTAAACAAACAATTTGAAGTTA
AACATTTCATTTTTAAAAACACTGAATTACAGTTCTTATTGATGACTTTTTAATGCAGAGTAAGTTGTTTAAGAAAGGCCTGAATATATC
AGAACATCTGAGCACCATTTTAGAAGAGTCAACTCTTAAGATTATCATTAGAAAACAAATACGTCAACACCTATGAAAAGAAGCGGGGAA
AACAACAACAAGGACAACAACAAAAAACCAGTGAAATTCTACAAGTGTCCCTTTTAAAAATAGTGTGTGCTAACTAAGGGCTATTCATTC
TGCCATTTTTAACTTGAGACACATTTAAGAATAAAGTTGGATGTTCTTTTTCTGTGATTATGAAATGCAATAAAATCTGAATAAAGGGCA
AAGTTTCTTCCTGATCAGATTAGATTAAGTGCTTAGTTTTATTCCTAATTCTGCCCCTTTTAACCTGATGTGTACCTTACTCTTTCCTCC
CTCTCTTCCTCCCTTCCTCCTCTCCCCGCTCCTTTCCTGCATTTCTCCCTCCCTCCTTCCCTCGTCACATCTCTTATATGAGCACAGTAA
TTATGACCTTTTTGTTTTGGCTACAACTTGATTGAAACAAGTTCAAAATTTAAACAAGTTCATACAAGTTTTTAAAAATTCTCAACTGGT
AGCTTGCTTGCTGTGCGTCTTCCAAACTAAAGCCTGCAAGCGCCACAATTCTAAGTGCCGCCTTCCATTTTTTTTCAGTATGTTTTCACT
GGCTTATGTTTTCAGATATGATTTTCCTTTTTCGCATATATGGTTTAATAAATGGGGGATAATTTTTTTTTTGTAAATCCGTGCTTGTGC
CAAGTCTCATATTTCTTTGCCATCTCAGAATTATCTTTTTACCACCACTGTTTATAAAATTTCCTTAGAGACTTTTTGAAGGGAAAATAG
AGCAACAGGGAAAAATGAAAGAAATGTCTTGGTTACTGAGCTCTAAATAGACAGGTTTGATGGCACTTCTCATGATACATTTTAGTTATT
CTTATAAAAGCAAACAGGCAAACATGAGTGTAAATTAAAGACAAAAAGAAAACTCTGGTTTTATATTTGAGAACACGTGAAAAATCATGG
GTCAACATAAAATCTTGAGAACCTTCTACTTTCTCTGGGAAAGCATTATATAGTGGTGCATTAGTTTAGAAAGTCAGCTATGATTTTGCC
TATAGTTCTAGTTATTAGCTTTGGGGTTTTCTTGTACTTTAAGACATACCTGTAAATTGAACCTATTTGAATTATATTCCACTGTATGTG
TATTATGGCTCTTTTCCTATTAGAGCAACTTGTGTTTCCCTGATAATGTGTACATTTTTTAGGCATGTACTTAATAGTTCACAATGTTCT
AAATTTGGAAGGACTTAAAAAAAAAACTTGTTTAAATTTCCATCTGTTTTGTAATATCTAGCTCTATATGTAAATGATGGGTTTGTTGGT
ATTTAAAATGAATACAACTTGAATGTAATTAAAGTGCTGTTTTTTGGAAGCGATAAACTTTAAATATACTTATTAAAATGAAATTCTATT

>39595_39595_4_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000381293_YTHDC2_chr5_112926737_ENST00000161863_length(amino acids)=159AA_BP=2
MNLQGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWG

--------------------------------------------------------------
>39595_39595_5_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000381294_YTHDC2_chr5_112926737_ENST00000161863_length(transcript)=2342nt_BP=64nt
ATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACTGAATCTACAGGGCTCAAAATCTCCTTCGCCAAGACC
AAACATGCCTGTTCGATACTTCATAATGAAGAGTAGCAATTTGAGAAACCTTGAAATTTCTCAACAGAAGGGTATCTGGTCTACAACTCC
TAGTAATGAACGGAAGCTAAATCGAGCCTTTTGGGAAAGCAGCATAGTTTACTTGGTATTTTCTGTTCAAGGATCTGGACATTTCCAGGG
ATTTTCTAGGATGTCTTCTGAGATTGGAAGGGAAAAGAGTCAGGACTGGGGCTCTGCTGGACTAGGAGGAGTATTTAAGGTGGAGTGGAT
ACGAAAAGAAAGCCTTCCCTTTCAATTTGCACACCATTTACTCAATCCATGGAATGACAACAAGAAAGTGCAGATAAGCAGGGATGGGCA
GGAACTAGAACCTCTGGTTGGTGAACAGTTGCTCCAGTTATGGGAACGTCTTCCCTTGGGAGAAAAAAACACAACTGATTGACACTCAGA
ACTCTTAGCTGTGGAAGAACATCATGCCTATTTATAACCACTGAATGCACTGACTTTCAAAAACTGAGGTGGGGTGTGTGTTACGAATGG
GCTTTTTAACACTTTTAGAGTGTTGCTTTAGAACTACCATCTTCATATACAGGAGAAAGGAAGCATTTAAATTTTTATAGTGATTATAGA
GAATGATTATATGATGTTTGTAATGAATAAAATAGTAGTTTCATTATTTGGCACAATAGCAGTTTATTTTAAACAAACAATTTGAAGTTA
AACATTTCATTTTTAAAAACACTGAATTACAGTTCTTATTGATGACTTTTTAATGCAGAGTAAGTTGTTTAAGAAAGGCCTGAATATATC
AGAACATCTGAGCACCATTTTAGAAGAGTCAACTCTTAAGATTATCATTAGAAAACAAATACGTCAACACCTATGAAAAGAAGCGGGGAA
AACAACAACAAGGACAACAACAAAAAACCAGTGAAATTCTACAAGTGTCCCTTTTAAAAATAGTGTGTGCTAACTAAGGGCTATTCATTC
TGCCATTTTTAACTTGAGACACATTTAAGAATAAAGTTGGATGTTCTTTTTCTGTGATTATGAAATGCAATAAAATCTGAATAAAGGGCA
AAGTTTCTTCCTGATCAGATTAGATTAAGTGCTTAGTTTTATTCCTAATTCTGCCCCTTTTAACCTGATGTGTACCTTACTCTTTCCTCC
CTCTCTTCCTCCCTTCCTCCTCTCCCCGCTCCTTTCCTGCATTTCTCCCTCCCTCCTTCCCTCGTCACATCTCTTATATGAGCACAGTAA
TTATGACCTTTTTGTTTTGGCTACAACTTGATTGAAACAAGTTCAAAATTTAAACAAGTTCATACAAGTTTTTAAAAATTCTCAACTGGT
AGCTTGCTTGCTGTGCGTCTTCCAAACTAAAGCCTGCAAGCGCCACAATTCTAAGTGCCGCCTTCCATTTTTTTTCAGTATGTTTTCACT
GGCTTATGTTTTCAGATATGATTTTCCTTTTTCGCATATATGGTTTAATAAATGGGGGATAATTTTTTTTTTGTAAATCCGTGCTTGTGC
CAAGTCTCATATTTCTTTGCCATCTCAGAATTATCTTTTTACCACCACTGTTTATAAAATTTCCTTAGAGACTTTTTGAAGGGAAAATAG
AGCAACAGGGAAAAATGAAAGAAATGTCTTGGTTACTGAGCTCTAAATAGACAGGTTTGATGGCACTTCTCATGATACATTTTAGTTATT
CTTATAAAAGCAAACAGGCAAACATGAGTGTAAATTAAAGACAAAAAGAAAACTCTGGTTTTATATTTGAGAACACGTGAAAAATCATGG
GTCAACATAAAATCTTGAGAACCTTCTACTTTCTCTGGGAAAGCATTATATAGTGGTGCATTAGTTTAGAAAGTCAGCTATGATTTTGCC
TATAGTTCTAGTTATTAGCTTTGGGGTTTTCTTGTACTTTAAGACATACCTGTAAATTGAACCTATTTGAATTATATTCCACTGTATGTG
TATTATGGCTCTTTTCCTATTAGAGCAACTTGTGTTTCCCTGATAATGTGTACATTTTTTAGGCATGTACTTAATAGTTCACAATGTTCT
AAATTTGGAAGGACTTAAAAAAAAAACTTGTTTAAATTTCCATCTGTTTTGTAATATCTAGCTCTATATGTAAATGATGGGTTTGTTGGT
ATTTAAAATGAATACAACTTGAATGTAATTAAAGTGCTGTTTTTTGGAAGCGATAAACTTTAAATATACTTATTAAAATGAAATTCTATT

>39595_39595_5_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000381294_YTHDC2_chr5_112926737_ENST00000161863_length(amino acids)=159AA_BP=2
MNLQGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWG

--------------------------------------------------------------
>39595_39595_6_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000396816_YTHDC2_chr5_112926737_ENST00000161863_length(transcript)=2342nt_BP=64nt
ATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACTGAATCTACAGGGCTCAAAATCTCCTTCGCCAAGACC
AAACATGCCTGTTCGATACTTCATAATGAAGAGTAGCAATTTGAGAAACCTTGAAATTTCTCAACAGAAGGGTATCTGGTCTACAACTCC
TAGTAATGAACGGAAGCTAAATCGAGCCTTTTGGGAAAGCAGCATAGTTTACTTGGTATTTTCTGTTCAAGGATCTGGACATTTCCAGGG
ATTTTCTAGGATGTCTTCTGAGATTGGAAGGGAAAAGAGTCAGGACTGGGGCTCTGCTGGACTAGGAGGAGTATTTAAGGTGGAGTGGAT
ACGAAAAGAAAGCCTTCCCTTTCAATTTGCACACCATTTACTCAATCCATGGAATGACAACAAGAAAGTGCAGATAAGCAGGGATGGGCA
GGAACTAGAACCTCTGGTTGGTGAACAGTTGCTCCAGTTATGGGAACGTCTTCCCTTGGGAGAAAAAAACACAACTGATTGACACTCAGA
ACTCTTAGCTGTGGAAGAACATCATGCCTATTTATAACCACTGAATGCACTGACTTTCAAAAACTGAGGTGGGGTGTGTGTTACGAATGG
GCTTTTTAACACTTTTAGAGTGTTGCTTTAGAACTACCATCTTCATATACAGGAGAAAGGAAGCATTTAAATTTTTATAGTGATTATAGA
GAATGATTATATGATGTTTGTAATGAATAAAATAGTAGTTTCATTATTTGGCACAATAGCAGTTTATTTTAAACAAACAATTTGAAGTTA
AACATTTCATTTTTAAAAACACTGAATTACAGTTCTTATTGATGACTTTTTAATGCAGAGTAAGTTGTTTAAGAAAGGCCTGAATATATC
AGAACATCTGAGCACCATTTTAGAAGAGTCAACTCTTAAGATTATCATTAGAAAACAAATACGTCAACACCTATGAAAAGAAGCGGGGAA
AACAACAACAAGGACAACAACAAAAAACCAGTGAAATTCTACAAGTGTCCCTTTTAAAAATAGTGTGTGCTAACTAAGGGCTATTCATTC
TGCCATTTTTAACTTGAGACACATTTAAGAATAAAGTTGGATGTTCTTTTTCTGTGATTATGAAATGCAATAAAATCTGAATAAAGGGCA
AAGTTTCTTCCTGATCAGATTAGATTAAGTGCTTAGTTTTATTCCTAATTCTGCCCCTTTTAACCTGATGTGTACCTTACTCTTTCCTCC
CTCTCTTCCTCCCTTCCTCCTCTCCCCGCTCCTTTCCTGCATTTCTCCCTCCCTCCTTCCCTCGTCACATCTCTTATATGAGCACAGTAA
TTATGACCTTTTTGTTTTGGCTACAACTTGATTGAAACAAGTTCAAAATTTAAACAAGTTCATACAAGTTTTTAAAAATTCTCAACTGGT
AGCTTGCTTGCTGTGCGTCTTCCAAACTAAAGCCTGCAAGCGCCACAATTCTAAGTGCCGCCTTCCATTTTTTTTCAGTATGTTTTCACT
GGCTTATGTTTTCAGATATGATTTTCCTTTTTCGCATATATGGTTTAATAAATGGGGGATAATTTTTTTTTTGTAAATCCGTGCTTGTGC
CAAGTCTCATATTTCTTTGCCATCTCAGAATTATCTTTTTACCACCACTGTTTATAAAATTTCCTTAGAGACTTTTTGAAGGGAAAATAG
AGCAACAGGGAAAAATGAAAGAAATGTCTTGGTTACTGAGCTCTAAATAGACAGGTTTGATGGCACTTCTCATGATACATTTTAGTTATT
CTTATAAAAGCAAACAGGCAAACATGAGTGTAAATTAAAGACAAAAAGAAAACTCTGGTTTTATATTTGAGAACACGTGAAAAATCATGG
GTCAACATAAAATCTTGAGAACCTTCTACTTTCTCTGGGAAAGCATTATATAGTGGTGCATTAGTTTAGAAAGTCAGCTATGATTTTGCC
TATAGTTCTAGTTATTAGCTTTGGGGTTTTCTTGTACTTTAAGACATACCTGTAAATTGAACCTATTTGAATTATATTCCACTGTATGTG
TATTATGGCTCTTTTCCTATTAGAGCAACTTGTGTTTCCCTGATAATGTGTACATTTTTTAGGCATGTACTTAATAGTTCACAATGTTCT
AAATTTGGAAGGACTTAAAAAAAAAACTTGTTTAAATTTCCATCTGTTTTGTAATATCTAGCTCTATATGTAAATGATGGGTTTGTTGGT
ATTTAAAATGAATACAACTTGAATGTAATTAAAGTGCTGTTTTTTGGAAGCGATAAACTTTAAATATACTTATTAAAATGAAATTCTATT

>39595_39595_6_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000396816_YTHDC2_chr5_112926737_ENST00000161863_length(amino acids)=159AA_BP=2
MNLQGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWG

--------------------------------------------------------------
>39595_39595_7_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000502326_YTHDC2_chr5_112926737_ENST00000161863_length(transcript)=2538nt_BP=260nt
AGGATCTGACAGTGTTCCGGAGCCGGGGCGAGCAGCCAAAAGGCCCGCGGAGTCGCGCTGGGCCGCCCCGGCGCAGCTGAACCGGGGGCC
GCGCCTGCCAGGCCGACGGGTCTGGCCCAGCCTGGCGCCAAGGGGTTCGTGCGCTGTGGAGACGCGGAGGGTCGAGGCGGCGCGGCCTGA
GAAATATCCGCGCAAGATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACTGAATCTACAGGGCTCAAAAT
CTCCTTCGCCAAGACCAAACATGCCTGTTCGATACTTCATAATGAAGAGTAGCAATTTGAGAAACCTTGAAATTTCTCAACAGAAGGGTA
TCTGGTCTACAACTCCTAGTAATGAACGGAAGCTAAATCGAGCCTTTTGGGAAAGCAGCATAGTTTACTTGGTATTTTCTGTTCAAGGAT
CTGGACATTTCCAGGGATTTTCTAGGATGTCTTCTGAGATTGGAAGGGAAAAGAGTCAGGACTGGGGCTCTGCTGGACTAGGAGGAGTAT
TTAAGGTGGAGTGGATACGAAAAGAAAGCCTTCCCTTTCAATTTGCACACCATTTACTCAATCCATGGAATGACAACAAGAAAGTGCAGA
TAAGCAGGGATGGGCAGGAACTAGAACCTCTGGTTGGTGAACAGTTGCTCCAGTTATGGGAACGTCTTCCCTTGGGAGAAAAAAACACAA
CTGATTGACACTCAGAACTCTTAGCTGTGGAAGAACATCATGCCTATTTATAACCACTGAATGCACTGACTTTCAAAAACTGAGGTGGGG
TGTGTGTTACGAATGGGCTTTTTAACACTTTTAGAGTGTTGCTTTAGAACTACCATCTTCATATACAGGAGAAAGGAAGCATTTAAATTT
TTATAGTGATTATAGAGAATGATTATATGATGTTTGTAATGAATAAAATAGTAGTTTCATTATTTGGCACAATAGCAGTTTATTTTAAAC
AAACAATTTGAAGTTAAACATTTCATTTTTAAAAACACTGAATTACAGTTCTTATTGATGACTTTTTAATGCAGAGTAAGTTGTTTAAGA
AAGGCCTGAATATATCAGAACATCTGAGCACCATTTTAGAAGAGTCAACTCTTAAGATTATCATTAGAAAACAAATACGTCAACACCTAT
GAAAAGAAGCGGGGAAAACAACAACAAGGACAACAACAAAAAACCAGTGAAATTCTACAAGTGTCCCTTTTAAAAATAGTGTGTGCTAAC
TAAGGGCTATTCATTCTGCCATTTTTAACTTGAGACACATTTAAGAATAAAGTTGGATGTTCTTTTTCTGTGATTATGAAATGCAATAAA
ATCTGAATAAAGGGCAAAGTTTCTTCCTGATCAGATTAGATTAAGTGCTTAGTTTTATTCCTAATTCTGCCCCTTTTAACCTGATGTGTA
CCTTACTCTTTCCTCCCTCTCTTCCTCCCTTCCTCCTCTCCCCGCTCCTTTCCTGCATTTCTCCCTCCCTCCTTCCCTCGTCACATCTCT
TATATGAGCACAGTAATTATGACCTTTTTGTTTTGGCTACAACTTGATTGAAACAAGTTCAAAATTTAAACAAGTTCATACAAGTTTTTA
AAAATTCTCAACTGGTAGCTTGCTTGCTGTGCGTCTTCCAAACTAAAGCCTGCAAGCGCCACAATTCTAAGTGCCGCCTTCCATTTTTTT
TCAGTATGTTTTCACTGGCTTATGTTTTCAGATATGATTTTCCTTTTTCGCATATATGGTTTAATAAATGGGGGATAATTTTTTTTTTGT
AAATCCGTGCTTGTGCCAAGTCTCATATTTCTTTGCCATCTCAGAATTATCTTTTTACCACCACTGTTTATAAAATTTCCTTAGAGACTT
TTTGAAGGGAAAATAGAGCAACAGGGAAAAATGAAAGAAATGTCTTGGTTACTGAGCTCTAAATAGACAGGTTTGATGGCACTTCTCATG
ATACATTTTAGTTATTCTTATAAAAGCAAACAGGCAAACATGAGTGTAAATTAAAGACAAAAAGAAAACTCTGGTTTTATATTTGAGAAC
ACGTGAAAAATCATGGGTCAACATAAAATCTTGAGAACCTTCTACTTTCTCTGGGAAAGCATTATATAGTGGTGCATTAGTTTAGAAAGT
CAGCTATGATTTTGCCTATAGTTCTAGTTATTAGCTTTGGGGTTTTCTTGTACTTTAAGACATACCTGTAAATTGAACCTATTTGAATTA
TATTCCACTGTATGTGTATTATGGCTCTTTTCCTATTAGAGCAACTTGTGTTTCCCTGATAATGTGTACATTTTTTAGGCATGTACTTAA
TAGTTCACAATGTTCTAAATTTGGAAGGACTTAAAAAAAAAACTTGTTTAAATTTCCATCTGTTTTGTAATATCTAGCTCTATATGTAAA
TGATGGGTTTGTTGGTATTTAAAATGAATACAACTTGAATGTAATTAAAGTGCTGTTTTTTGGAAGCGATAAACTTTAAATATACTTATT

>39595_39595_7_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000502326_YTHDC2_chr5_112926737_ENST00000161863_length(amino acids)=159AA_BP=2
MNLQGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWG

--------------------------------------------------------------
>39595_39595_8_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000522633_YTHDC2_chr5_112926737_ENST00000161863_length(transcript)=2434nt_BP=156nt
GGAAAAAGCATGACATTTAGAAGTAGAAGACTTAGCTTCAAATCCCTACTCCTTCACTTACTAATTTTGTGATTTGGAAATATCCGCGCA
AGATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACTGAATCTACAGGGCTCAAAATCTCCTTCGCCAAGA
CCAAACATGCCTGTTCGATACTTCATAATGAAGAGTAGCAATTTGAGAAACCTTGAAATTTCTCAACAGAAGGGTATCTGGTCTACAACT
CCTAGTAATGAACGGAAGCTAAATCGAGCCTTTTGGGAAAGCAGCATAGTTTACTTGGTATTTTCTGTTCAAGGATCTGGACATTTCCAG
GGATTTTCTAGGATGTCTTCTGAGATTGGAAGGGAAAAGAGTCAGGACTGGGGCTCTGCTGGACTAGGAGGAGTATTTAAGGTGGAGTGG
ATACGAAAAGAAAGCCTTCCCTTTCAATTTGCACACCATTTACTCAATCCATGGAATGACAACAAGAAAGTGCAGATAAGCAGGGATGGG
CAGGAACTAGAACCTCTGGTTGGTGAACAGTTGCTCCAGTTATGGGAACGTCTTCCCTTGGGAGAAAAAAACACAACTGATTGACACTCA
GAACTCTTAGCTGTGGAAGAACATCATGCCTATTTATAACCACTGAATGCACTGACTTTCAAAAACTGAGGTGGGGTGTGTGTTACGAAT
GGGCTTTTTAACACTTTTAGAGTGTTGCTTTAGAACTACCATCTTCATATACAGGAGAAAGGAAGCATTTAAATTTTTATAGTGATTATA
GAGAATGATTATATGATGTTTGTAATGAATAAAATAGTAGTTTCATTATTTGGCACAATAGCAGTTTATTTTAAACAAACAATTTGAAGT
TAAACATTTCATTTTTAAAAACACTGAATTACAGTTCTTATTGATGACTTTTTAATGCAGAGTAAGTTGTTTAAGAAAGGCCTGAATATA
TCAGAACATCTGAGCACCATTTTAGAAGAGTCAACTCTTAAGATTATCATTAGAAAACAAATACGTCAACACCTATGAAAAGAAGCGGGG
AAAACAACAACAAGGACAACAACAAAAAACCAGTGAAATTCTACAAGTGTCCCTTTTAAAAATAGTGTGTGCTAACTAAGGGCTATTCAT
TCTGCCATTTTTAACTTGAGACACATTTAAGAATAAAGTTGGATGTTCTTTTTCTGTGATTATGAAATGCAATAAAATCTGAATAAAGGG
CAAAGTTTCTTCCTGATCAGATTAGATTAAGTGCTTAGTTTTATTCCTAATTCTGCCCCTTTTAACCTGATGTGTACCTTACTCTTTCCT
CCCTCTCTTCCTCCCTTCCTCCTCTCCCCGCTCCTTTCCTGCATTTCTCCCTCCCTCCTTCCCTCGTCACATCTCTTATATGAGCACAGT
AATTATGACCTTTTTGTTTTGGCTACAACTTGATTGAAACAAGTTCAAAATTTAAACAAGTTCATACAAGTTTTTAAAAATTCTCAACTG
GTAGCTTGCTTGCTGTGCGTCTTCCAAACTAAAGCCTGCAAGCGCCACAATTCTAAGTGCCGCCTTCCATTTTTTTTCAGTATGTTTTCA
CTGGCTTATGTTTTCAGATATGATTTTCCTTTTTCGCATATATGGTTTAATAAATGGGGGATAATTTTTTTTTTGTAAATCCGTGCTTGT
GCCAAGTCTCATATTTCTTTGCCATCTCAGAATTATCTTTTTACCACCACTGTTTATAAAATTTCCTTAGAGACTTTTTGAAGGGAAAAT
AGAGCAACAGGGAAAAATGAAAGAAATGTCTTGGTTACTGAGCTCTAAATAGACAGGTTTGATGGCACTTCTCATGATACATTTTAGTTA
TTCTTATAAAAGCAAACAGGCAAACATGAGTGTAAATTAAAGACAAAAAGAAAACTCTGGTTTTATATTTGAGAACACGTGAAAAATCAT
GGGTCAACATAAAATCTTGAGAACCTTCTACTTTCTCTGGGAAAGCATTATATAGTGGTGCATTAGTTTAGAAAGTCAGCTATGATTTTG
CCTATAGTTCTAGTTATTAGCTTTGGGGTTTTCTTGTACTTTAAGACATACCTGTAAATTGAACCTATTTGAATTATATTCCACTGTATG
TGTATTATGGCTCTTTTCCTATTAGAGCAACTTGTGTTTCCCTGATAATGTGTACATTTTTTAGGCATGTACTTAATAGTTCACAATGTT
CTAAATTTGGAAGGACTTAAAAAAAAAACTTGTTTAAATTTCCATCTGTTTTGTAATATCTAGCTCTATATGTAAATGATGGGTTTGTTG
GTATTTAAAATGAATACAACTTGAATGTAATTAAAGTGCTGTTTTTTGGAAGCGATAAACTTTAAATATACTTATTAAAATGAAATTCTA

>39595_39595_8_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000522633_YTHDC2_chr5_112926737_ENST00000161863_length(amino acids)=159AA_BP=2
MNLQGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWG

--------------------------------------------------------------
>39595_39595_9_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000536319_YTHDC2_chr5_112926737_ENST00000161863_length(transcript)=2342nt_BP=64nt
ATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCTCACCACTGAATCTACAGGGCTCAAAATCTCCTTCGCCAAGACC
AAACATGCCTGTTCGATACTTCATAATGAAGAGTAGCAATTTGAGAAACCTTGAAATTTCTCAACAGAAGGGTATCTGGTCTACAACTCC
TAGTAATGAACGGAAGCTAAATCGAGCCTTTTGGGAAAGCAGCATAGTTTACTTGGTATTTTCTGTTCAAGGATCTGGACATTTCCAGGG
ATTTTCTAGGATGTCTTCTGAGATTGGAAGGGAAAAGAGTCAGGACTGGGGCTCTGCTGGACTAGGAGGAGTATTTAAGGTGGAGTGGAT
ACGAAAAGAAAGCCTTCCCTTTCAATTTGCACACCATTTACTCAATCCATGGAATGACAACAAGAAAGTGCAGATAAGCAGGGATGGGCA
GGAACTAGAACCTCTGGTTGGTGAACAGTTGCTCCAGTTATGGGAACGTCTTCCCTTGGGAGAAAAAAACACAACTGATTGACACTCAGA
ACTCTTAGCTGTGGAAGAACATCATGCCTATTTATAACCACTGAATGCACTGACTTTCAAAAACTGAGGTGGGGTGTGTGTTACGAATGG
GCTTTTTAACACTTTTAGAGTGTTGCTTTAGAACTACCATCTTCATATACAGGAGAAAGGAAGCATTTAAATTTTTATAGTGATTATAGA
GAATGATTATATGATGTTTGTAATGAATAAAATAGTAGTTTCATTATTTGGCACAATAGCAGTTTATTTTAAACAAACAATTTGAAGTTA
AACATTTCATTTTTAAAAACACTGAATTACAGTTCTTATTGATGACTTTTTAATGCAGAGTAAGTTGTTTAAGAAAGGCCTGAATATATC
AGAACATCTGAGCACCATTTTAGAAGAGTCAACTCTTAAGATTATCATTAGAAAACAAATACGTCAACACCTATGAAAAGAAGCGGGGAA
AACAACAACAAGGACAACAACAAAAAACCAGTGAAATTCTACAAGTGTCCCTTTTAAAAATAGTGTGTGCTAACTAAGGGCTATTCATTC
TGCCATTTTTAACTTGAGACACATTTAAGAATAAAGTTGGATGTTCTTTTTCTGTGATTATGAAATGCAATAAAATCTGAATAAAGGGCA
AAGTTTCTTCCTGATCAGATTAGATTAAGTGCTTAGTTTTATTCCTAATTCTGCCCCTTTTAACCTGATGTGTACCTTACTCTTTCCTCC
CTCTCTTCCTCCCTTCCTCCTCTCCCCGCTCCTTTCCTGCATTTCTCCCTCCCTCCTTCCCTCGTCACATCTCTTATATGAGCACAGTAA
TTATGACCTTTTTGTTTTGGCTACAACTTGATTGAAACAAGTTCAAAATTTAAACAAGTTCATACAAGTTTTTAAAAATTCTCAACTGGT
AGCTTGCTTGCTGTGCGTCTTCCAAACTAAAGCCTGCAAGCGCCACAATTCTAAGTGCCGCCTTCCATTTTTTTTCAGTATGTTTTCACT
GGCTTATGTTTTCAGATATGATTTTCCTTTTTCGCATATATGGTTTAATAAATGGGGGATAATTTTTTTTTTGTAAATCCGTGCTTGTGC
CAAGTCTCATATTTCTTTGCCATCTCAGAATTATCTTTTTACCACCACTGTTTATAAAATTTCCTTAGAGACTTTTTGAAGGGAAAATAG
AGCAACAGGGAAAAATGAAAGAAATGTCTTGGTTACTGAGCTCTAAATAGACAGGTTTGATGGCACTTCTCATGATACATTTTAGTTATT
CTTATAAAAGCAAACAGGCAAACATGAGTGTAAATTAAAGACAAAAAGAAAACTCTGGTTTTATATTTGAGAACACGTGAAAAATCATGG
GTCAACATAAAATCTTGAGAACCTTCTACTTTCTCTGGGAAAGCATTATATAGTGGTGCATTAGTTTAGAAAGTCAGCTATGATTTTGCC
TATAGTTCTAGTTATTAGCTTTGGGGTTTTCTTGTACTTTAAGACATACCTGTAAATTGAACCTATTTGAATTATATTCCACTGTATGTG
TATTATGGCTCTTTTCCTATTAGAGCAACTTGTGTTTCCCTGATAATGTGTACATTTTTTAGGCATGTACTTAATAGTTCACAATGTTCT
AAATTTGGAAGGACTTAAAAAAAAAACTTGTTTAAATTTCCATCTGTTTTGTAATATCTAGCTCTATATGTAAATGATGGGTTTGTTGGT
ATTTAAAATGAATACAACTTGAATGTAATTAAAGTGCTGTTTTTTGGAAGCGATAAACTTTAAATATACTTATTAAAATGAAATTCTATT

>39595_39595_9_IL6ST-YTHDC2_IL6ST_chr5_55272042_ENST00000536319_YTHDC2_chr5_112926737_ENST00000161863_length(amino acids)=159AA_BP=2
MNLQGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for IL6ST-YTHDC2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for IL6ST-YTHDC2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for IL6ST-YTHDC2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource