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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ING4-NCAPD2 (FusionGDB2 ID:39747)

Fusion Gene Summary for ING4-NCAPD2

check button Fusion gene summary
Fusion gene informationFusion gene name: ING4-NCAPD2
Fusion gene ID: 39747
HgeneTgene
Gene symbol

ING4

NCAPD2

Gene ID

51147

9918

Gene nameinhibitor of growth family member 4non-SMC condensin I complex subunit D2
Synonymsmy036|p29ING4CAP-D2|CNAP1|MCPH21|hCAP-D2
Cytomap

12p13.31

12p13.31

Type of geneprotein-codingprotein-coding
Descriptioninhibitor of growth protein 4brain my036 proteincandidate tumor suppressor p33 ING1 homologcondensin complex subunit 1XCAP-D2 homologchromosome condensation-related SMC-associated protein 1chromosome-associated protein D2
Modification date2020032220200313
UniProtAcc

Q9UNL4

Q15021

Ensembl transtripts involved in fusion geneENST00000341550, ENST00000396807, 
ENST00000412586, ENST00000423703, 
ENST00000446105, ENST00000486287, 
ENST00000444704, 		ENST00000542492, 
ENST00000315579, ENST00000545962, 
Fusion gene scores* DoF score3 X 3 X 3=276 X 6 X 5=180
# samples 36
** MAII scorelog2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(6/180*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ING4 [Title/Abstract] AND NCAPD2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointING4(6765892)-NCAPD2(6618882), # samples:1
Anticipated loss of major functional domain due to fusion event.ING4-NCAPD2 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
ING4-NCAPD2 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
ING4-NCAPD2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneING4

GO:0006260

DNA replication

16387653

HgeneING4

GO:0006473

protein acetylation

12750254

HgeneING4

GO:0006915

apoptotic process

15251430

HgeneING4

GO:0006978

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

16387653

HgeneING4

GO:0007050

cell cycle arrest

15251430

HgeneING4

GO:0008285

negative regulation of cell proliferation

12750254|15251430

HgeneING4

GO:0043065

positive regulation of apoptotic process

16387653

HgeneING4

GO:0043966

histone H3 acetylation

16387653

HgeneING4

GO:0043981

histone H4-K5 acetylation

16387653

HgeneING4

GO:0043982

histone H4-K8 acetylation

16387653

HgeneING4

GO:0043983

histone H4-K12 acetylation

16387653

HgeneING4

GO:0043984

histone H4-K16 acetylation

16387653

HgeneING4

GO:0045892

negative regulation of transcription, DNA-templated

15029197

HgeneING4

GO:0045926

negative regulation of growth

12750254

TgeneNCAPD2

GO:0007076

mitotic chromosome condensation

11136719


check buttonFusion gene breakpoints across ING4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NCAPD2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-Cancer43NING4chr12

6765892

-NCAPD2chr12

6618882

+


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Fusion Gene ORF analysis for ING4-NCAPD2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000341550ENST00000542492ING4chr12

6765892

-NCAPD2chr12

6618882

+
5CDS-intronENST00000396807ENST00000542492ING4chr12

6765892

-NCAPD2chr12

6618882

+
5CDS-intronENST00000412586ENST00000542492ING4chr12

6765892

-NCAPD2chr12

6618882

+
5CDS-intronENST00000423703ENST00000542492ING4chr12

6765892

-NCAPD2chr12

6618882

+
5CDS-intronENST00000446105ENST00000542492ING4chr12

6765892

-NCAPD2chr12

6618882

+
5UTR-3CDSENST00000486287ENST00000315579ING4chr12

6765892

-NCAPD2chr12

6618882

+
5UTR-3CDSENST00000486287ENST00000545962ING4chr12

6765892

-NCAPD2chr12

6618882

+
5UTR-intronENST00000486287ENST00000542492ING4chr12

6765892

-NCAPD2chr12

6618882

+
Frame-shiftENST00000341550ENST00000545962ING4chr12

6765892

-NCAPD2chr12

6618882

+
Frame-shiftENST00000396807ENST00000545962ING4chr12

6765892

-NCAPD2chr12

6618882

+
Frame-shiftENST00000412586ENST00000545962ING4chr12

6765892

-NCAPD2chr12

6618882

+
Frame-shiftENST00000423703ENST00000315579ING4chr12

6765892

-NCAPD2chr12

6618882

+
Frame-shiftENST00000446105ENST00000545962ING4chr12

6765892

-NCAPD2chr12

6618882

+
In-frameENST00000341550ENST00000315579ING4chr12

6765892

-NCAPD2chr12

6618882

+
In-frameENST00000396807ENST00000315579ING4chr12

6765892

-NCAPD2chr12

6618882

+
In-frameENST00000412586ENST00000315579ING4chr12

6765892

-NCAPD2chr12

6618882

+
In-frameENST00000423703ENST00000545962ING4chr12

6765892

-NCAPD2chr12

6618882

+
In-frameENST00000446105ENST00000315579ING4chr12

6765892

-NCAPD2chr12

6618882

+
intron-3CDSENST00000444704ENST00000315579ING4chr12

6765892

-NCAPD2chr12

6618882

+
intron-3CDSENST00000444704ENST00000545962ING4chr12

6765892

-NCAPD2chr12

6618882

+
intron-intronENST00000444704ENST00000542492ING4chr12

6765892

-NCAPD2chr12

6618882

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000341550ING4chr126765892-ENST00000315579NCAPD2chr126618882+47781563242341400
ENST00000396807ING4chr126765892-ENST00000315579NCAPD2chr126618882+47701482442261400
ENST00000446105ING4chr126765892-ENST00000315579NCAPD2chr126618882+47721502642281400
ENST00000423703ING4chr126765892-ENST00000545962NCAPD2chr126618882+419310911841281336
ENST00000412586ING4chr126765892-ENST00000315579NCAPD2chr126618882+4731109041871395

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000341550ENST00000315579ING4chr126765892-NCAPD2chr126618882+0.0007041620.99929583
ENST00000396807ENST00000315579ING4chr126765892-NCAPD2chr126618882+0.0007199910.99928004
ENST00000446105ENST00000315579ING4chr126765892-NCAPD2chr126618882+0.0007171050.9992829
ENST00000423703ENST00000545962ING4chr126765892-NCAPD2chr126618882+0.001405870.9985941
ENST00000412586ENST00000315579ING4chr126765892-NCAPD2chr126618882+0.0006884740.99931157

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Fusion Genomic Features for ING4-NCAPD2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ING4chr126765892-NCAPD2chr126618882+0.0003076980.9996923
ING4chr126765892-NCAPD2chr126618882+0.0003076980.9996923

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ING4-NCAPD2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:6765892/chr12:6618882)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ING4

Q9UNL4

NCAPD2

Q15021

FUNCTION: Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4 (PubMed:16387653). Through chromatin acetylation it may function in DNA replication (PubMed:16387653). May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation (PubMed:15251430, PubMed:15528276). Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA (PubMed:15029197). May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC (PubMed:15029197). Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1) (PubMed:15897452). Can enhance apoptosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity). {ECO:0000250|UniProtKB:Q8C0D7, ECO:0000269|PubMed:15029197, ECO:0000269|PubMed:15251430, ECO:0000269|PubMed:15528276, ECO:0000269|PubMed:15897452, ECO:0000269|PubMed:16387653}.FUNCTION: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain (PubMed:11136719). May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size (PubMed:27737959). {ECO:0000269|PubMed:11136719, ECO:0000269|PubMed:27737959}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNCAPD2chr12:6765892chr12:6618882ENST000003155791321342_1362421402.0MotifNote=Bipartite nuclear localization signal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneING4chr12:6765892chr12:6618882ENST00000341550-2825_11836249.0Coiled coilOntology_term=ECO:0000269
HgeneING4chr12:6765892chr12:6618882ENST00000396807-2825_11836250.0Coiled coilOntology_term=ECO:0000269
HgeneING4chr12:6765892chr12:6618882ENST00000412586-2825_11836247.0Coiled coilOntology_term=ECO:0000269
HgeneING4chr12:6765892chr12:6618882ENST00000423703-2725_11836177.66666666666666Coiled coilOntology_term=ECO:0000269
HgeneING4chr12:6765892chr12:6618882ENST00000444704-1725_1180226.0Coiled coilOntology_term=ECO:0000269
HgeneING4chr12:6765892chr12:6618882ENST00000446105-2825_11836246.0Coiled coilOntology_term=ECO:0000269
HgeneING4chr12:6765892chr12:6618882ENST00000341550-28127_14836249.0MotifNote=Bipartite nuclear localization signal
HgeneING4chr12:6765892chr12:6618882ENST00000396807-28127_14836250.0MotifNote=Bipartite nuclear localization signal
HgeneING4chr12:6765892chr12:6618882ENST00000412586-28127_14836247.0MotifNote=Bipartite nuclear localization signal
HgeneING4chr12:6765892chr12:6618882ENST00000423703-27127_14836177.66666666666666MotifNote=Bipartite nuclear localization signal
HgeneING4chr12:6765892chr12:6618882ENST00000444704-17127_1480226.0MotifNote=Bipartite nuclear localization signal
HgeneING4chr12:6765892chr12:6618882ENST00000446105-28127_14836246.0MotifNote=Bipartite nuclear localization signal
HgeneING4chr12:6765892chr12:6618882ENST00000341550-28196_24536249.0Zinc fingerPHD-type
HgeneING4chr12:6765892chr12:6618882ENST00000396807-28196_24536250.0Zinc fingerPHD-type
HgeneING4chr12:6765892chr12:6618882ENST00000412586-28196_24536247.0Zinc fingerPHD-type
HgeneING4chr12:6765892chr12:6618882ENST00000423703-27196_24536177.66666666666666Zinc fingerPHD-type
HgeneING4chr12:6765892chr12:6618882ENST00000444704-17196_2450226.0Zinc fingerPHD-type
HgeneING4chr12:6765892chr12:6618882ENST00000446105-28196_24536246.0Zinc fingerPHD-type


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Fusion Gene Sequence for ING4-NCAPD2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>39747_39747_1_ING4-NCAPD2_ING4_chr12_6765892_ENST00000341550_NCAPD2_chr12_6618882_ENST00000315579_length(transcript)=4778nt_BP=156nt
ACAGTCACTTCCGGGGCGGATCGGAAGTTGCTTTGTTTTGCTTCGAGATGGCTGCGGGGATGTATTTGGAACATTATCTGGACAGTATTG
AAAACCTTCCCTTTGAATTACAGAGAAACTTTCAGCTCATGAGGGACCTAGACCAAAGAACAGAGGCTTTTCAGGCTGCCTTTCGAGCTC
AGGGGCCCCTGGCTATGCTGCAGCACTTTGATACTATCTACAGCATTTTGCATCACTTTCGAAGTATAGATCCTGGCCTCAAAGAAGATA
CTCTGCAATTCCTGATAAAAGTGGTATCCCGCCACTCCCAGGAGCTTCCAGCTATCCTGGATGATACAACTTTGAGTGGATCAGATAGAA
ACGCCCATCTAAATGCCCTCAAAATGAACTGTTATGCTCTGATACGTCTCCTGGAATCCTTTGAGACCATGGCCAGCCAGACAAACCTTG
TGGACCTGGACCTTGGTGGGAAGGGTAAGAAAGCTCGGACCAAGGCAGCCCATGGCTTTGACTGGGAAGAAGAGAGGCAACCAATTCTTC
AGCTTTTAACACAGCTACTTCAGTTGGACATCCGTCACCTGTGGAACCACTCAATAATTGAAGAAGAATTTGTCAGTTTGGTTACTGGCT
GTTGCTACCGCCTTCTGGAGAATCCCACCATTAATCACCAGAAGAACCGCCCCACTCGGGAAGCCATAACACACCTGCTTGGTGTAGCCT
TGACCCGTTATAACCATATGCTCAGTGCTACAGTGAAGATCATCCAGATGCTGCAGCACTTTGAACACCTGGCACCTGTACTGGTTGCAG
CCGTGAGTCTATGGGCAACTGACTATGGAATGAAGAGCATAGTGGGAGAGATTGTAAGAGAGATTGGACAAAAGTGTCCCCAAGAGCTGA
GTCGAGACCCTTCAGGGACAAAGGGCTTTGCAGCATTCCTGACAGAACTAGCAGAACGTGTCCCAGCTATCCTGATGTCCAGCATGTGCA
TTTTGCTAGATCACCTGGATGGAGAAAATTACATGATGCGTAATGCTGTGCTGGCAGCCATGGCGGAGATGGTGCTGCAGGTTCTCAGTG
GCGATCAACTGGAAGCAGCAGCCCGAGACACCAGAGACCAGTTCTTGGATACTTTACAAGCCCATGGCCATGATGTCAACTCCTTTGTGC
GGAGCCGTGTTTTGCAGCTCTTCACCCGAATTGTCCAGCAGAAGGCTCTCCCCCTGACACGTTTCCAGGCAGTGGTGGCTTTAGCTGTGG
GACGTCTGGCAGACAAGTCAGTGCTAGTATGTAAAAATGCCATCCAGCTGCTGGCCAGTTTTCTAGCCAATAATCCTTTCTCCTGCAAGC
TTAGTGATGCTGACCTTGCCGGACCACTGCAGAAGGAGACCCAGAAATTACAAGAGATGAGGGCCCAGAGGCGAACTGCAGCAGCTTCTG
CAGTGCTGGACCCAGAGGAGGAGTGGGAAGCCATGCTGCCAGAGTTGAAGTCTACCCTGCAGCAGCTTCTACAGCTTCCCCAGGGAGAGG
AGGAGATTCCTGAGCAAATTGCCAATACAGAGACAACTGAAGATGTGAAAGGACGCATCTATCAACTGCTTGCCAAAGCTAGTTACAAAA
AGGCCATCATTCTCACTCGAGAAGCCACAGGCCACTTCCAGGAGTCCGAACCCTTCAGTCATATAGACCCAGAGGAGTCAGAGGAGACCA
GGCTCTTGAATATCTTAGGACTTATCTTCAAAGGCCCAGCAGCTTCCACACAAGAAAAGAATCCCCGGGAGTCTACAGGAAACATGGTCA
CAGGACAGACTGTCTGTAAAAATAAACCCAATATGTCGGATCCTGAGGAATCCAGGGGAAATGATGAACTAGTGAAGCAGGAGATGCTGG
TACAGTATCTGCAGGATGCCTACAGCTTCTCCCGGAAGATTACAGAGGCCATTGGCATCATCAGCAAGATGATGTATGAAAACACAACTA
CAGTGGTGCAGGAGGTGATTGAATTCTTTGTGATGGTCTTCCAATTTGGGGTACCCCAGGCCCTGTTTGGGGTGCGCCGTATGCTGCCTC
TCATCTGGTCTAAGGAGCCTGGTGTCCGGGAAGCCGTGCTTAATGCCTACCGCCAACTCTACCTCAACCCCAAAGGGGACTCTGCCAGAG
CCAAGGCCCAGGCTTTGATTCAGAATCTCTCTCTGCTGCTAGTGGATGCCTCGGTTGGGACCATTCAGTGTCTTGAGGAAATTCTCTGTG
AGTTTGTGCAGAAGGATGAGTTGAAACCAGCAGTGACCCAGCTGCTGTGGGAGCGGGCCACCGAGAAGGTCGCCTGCTGTCCTCTGGAGC
GCTGTTCCTCTGTCATGCTTCTTGGCATGATGGCACGAGGAAAGCCAGAAATTGTGGGAAGCAATTTAGACACACTGGTGAGCATAGGGC
TGGATGAGAAGTTTCCACAGGACTACAGGCTGGCCCAGCAGGTGTGCCATGCCATTGCCAACATCTCGGACAGGAGAAAGCCTTCTCTGG
GCAAACGTCACCCCCCCTTCCGGCTGCCTCAGGAACACAGGTTGTTTGAGCGACTGCGGGAGACAGTCACAAAAGGCTTTGTCCACCCAG
ACCCACTCTGGATCCCATTCAAAGAGGTGGCAGTGACCCTCATTTACCAACTGGCAGAGGGCCCCGAAGTGATCTGTGCCCAGATATTGC
AGGGCTGTGCAAAACAGGCCCTGGAGAAGCTAGAAGAGAAGAGAACCAGTCAGGAGGACCCGAAGGAGTCCCCCGCAATGCTCCCCACTT
TCCTGTTGATGAACCTGCTGTCCCTGGCTGGGGATGTGGCTCTGCAGCAGCTGGTCCACTTGGAGCAGGCAGTGAGTGGAGAGCTCTGCC
GGCGCCGAGTTCTCCGGGAAGAACAGGAGCACAAGACCAAAGATCCCAAGGAGAAGAATACGAGCTCTGAGACCACCATGGAGGAGGAGC
TGGGGCTGGTTGGGGCAACAGCAGATGACACAGAGGCAGAACTAATCCGTGGCATCTGCGAGATGGAACTGTTGGATGGCAAACAGACAC
TGGCTGCCTTTGTTCCACTCTTGCTTAAAGTCTGTAACAACCCAGGCCTCTATAGCAACCCAGACCTCTCTGCAGCTGCTTCACTTGCCC
TTGGCAAGTTCTGCATGATCAGTGCCACTTTCTGCGACTCCCAGCTTCGTCTTCTGTTCACCATGCTGGAAAAGTCTCCACTTCCCATTG
TCCGGTCTAACCTCATGGTTGCCACTGGGGATCTGGCCATCCGCTTTCCCAATCTGGTGGACCCCTGGACTCCTCATCTGTATGCTCGTC
TCCGGGACCCTGCTCAGCAAGTGCGGAAAACAGCGGGGCTGGTGATGACCCACCTGATCCTCAAGGACATGGTGAAGGTGAAGGGGCAGG
TCAGCGAGATGGCGGTGCTGCTCATCGACCCCGAGCCTCAGATTGCTGCCCTGGCCAAGAACTTCTTCAATGAGCTCTCCCACAAGGGCA
ACGCAATCTATAATCTCCTTCCAGATATCATCAGCCGCCTGTCAGACCCCGAGCTGGGGGTGGAGGAAGAGCCTTTCCACACCATCATGA
AACAGCTCCTCTCCTACATCACCAAGGACAAGCAGACAGAGAGCCTGGTGGAAAAGCTGTGTCAGCGGTTCCGCACATCCCGAACTGAGC
GGCAGCAGCGAGACCTGGCCTACTGTGTGTCACAGCTGCCCCTCACAGAGCGAGGCCTCCGTAAGATGCTTGACAATTTTGACTGTTTTG
GAGACAAACTGTCAGATGAGTCCATCTTCAGTGCTTTTTTGTCAGTTGTAGGCAAGCTGCGACGTGGGGCCAAGCCTGAGGGCAAGGCTA
TAATAGATGAATTTGAGCAGAAGCTTCGGGCCTGTCATACCAGAGGTTTGGATGGAATCAAGGAGCTTGAGATTGGCCAAGCAGGTAGCC
AGAGAGCGCCATCAGCCAAGAAACCATCCACTGGTTCTAGGTACCAGCCTCTGGCTTCTACAGCCTCAGACAATGACTTTGTCACACCAG
AGCCCCGCCGTACTACCCGTCGGCATCCAAACACCCAGCAGCGAGCTTCCAAAAAGAAACCCAAAGTTGTCTTCTCAAGTGATGAGTCCA
GTGAGGAAGATCTTTCAGCAGAGATGACAGAAGACGAGACACCCAAGAAAACAACTCCCATTCTCAGAGCATCGGCTCGCAGGCACAGAT
CCTAGGAAGTCTGTTCCTGTCCTCCCTGTGCAGGGTATCCTGTAGGGTGACCTGGAATTCGAATTCTGTTTCCCTTGTAAAATATTTGTC
TGTCTCTTTTTTTTAAAAAAAAAAAAGGCCGGGCACTGTGGCTCACGCCTGTAATCCCAGCACTTTGCGATACCAAGGCGGGTGGATAAC
CTGAGGTAGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATAAAAAATTAGCCGGGCGTATTGGCGTGC
GCCTGTAATCCCAGCTACTCAAGAGGCTGAGGCAGGAGAATCGCCTGAACCCAGAGGCGGAGGTTGTAGTGAGCCGAAATCACACCATTG
CACTCCAGCTTGGGCAACAATAGCGAACCTCCATCTCAAATTAAAAAAAAAATGCCTACACGCTCTTTAAAATGCAAGGCTTTCTCTTAA
ATTAGCCTAACTGAACTGCGTTGAGCTGCTTCAACTTTGGAATATATGTTTGCCAATCTCCTTGTTTTCTAATGAATAAATGTTTTTATA

>39747_39747_1_ING4-NCAPD2_ING4_chr12_6765892_ENST00000341550_NCAPD2_chr12_6618882_ENST00000315579_length(amino acids)=1400AA_BP=41
MFCFEMAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEAFQAAFRAQGPLAMLQHFDTIYSILHHFRSIDPGLKEDTLQFLIKVVSR
HSQELPAILDDTTLSGSDRNAHLNALKMNCYALIRLLESFETMASQTNLVDLDLGGKGKKARTKAAHGFDWEEERQPILQLLTQLLQLDI
RHLWNHSIIEEEFVSLVTGCCYRLLENPTINHQKNRPTREAITHLLGVALTRYNHMLSATVKIIQMLQHFEHLAPVLVAAVSLWATDYGM
KSIVGEIVREIGQKCPQELSRDPSGTKGFAAFLTELAERVPAILMSSMCILLDHLDGENYMMRNAVLAAMAEMVLQVLSGDQLEAAARDT
RDQFLDTLQAHGHDVNSFVRSRVLQLFTRIVQQKALPLTRFQAVVALAVGRLADKSVLVCKNAIQLLASFLANNPFSCKLSDADLAGPLQ
KETQKLQEMRAQRRTAAASAVLDPEEEWEAMLPELKSTLQQLLQLPQGEEEIPEQIANTETTEDVKGRIYQLLAKASYKKAIILTREATG
HFQESEPFSHIDPEESEETRLLNILGLIFKGPAASTQEKNPRESTGNMVTGQTVCKNKPNMSDPEESRGNDELVKQEMLVQYLQDAYSFS
RKITEAIGIISKMMYENTTTVVQEVIEFFVMVFQFGVPQALFGVRRMLPLIWSKEPGVREAVLNAYRQLYLNPKGDSARAKAQALIQNLS
LLLVDASVGTIQCLEEILCEFVQKDELKPAVTQLLWERATEKVACCPLERCSSVMLLGMMARGKPEIVGSNLDTLVSIGLDEKFPQDYRL
AQQVCHAIANISDRRKPSLGKRHPPFRLPQEHRLFERLRETVTKGFVHPDPLWIPFKEVAVTLIYQLAEGPEVICAQILQGCAKQALEKL
EEKRTSQEDPKESPAMLPTFLLMNLLSLAGDVALQQLVHLEQAVSGELCRRRVLREEQEHKTKDPKEKNTSSETTMEEELGLVGATADDT
EAELIRGICEMELLDGKQTLAAFVPLLLKVCNNPGLYSNPDLSAAASLALGKFCMISATFCDSQLRLLFTMLEKSPLPIVRSNLMVATGD
LAIRFPNLVDPWTPHLYARLRDPAQQVRKTAGLVMTHLILKDMVKVKGQVSEMAVLLIDPEPQIAALAKNFFNELSHKGNAIYNLLPDII
SRLSDPELGVEEEPFHTIMKQLLSYITKDKQTESLVEKLCQRFRTSRTERQQRDLAYCVSQLPLTERGLRKMLDNFDCFGDKLSDESIFS
AFLSVVGKLRRGAKPEGKAIIDEFEQKLRACHTRGLDGIKELEIGQAGSQRAPSAKKPSTGSRYQPLASTASDNDFVTPEPRRTTRRHPN

--------------------------------------------------------------
>39747_39747_2_ING4-NCAPD2_ING4_chr12_6765892_ENST00000396807_NCAPD2_chr12_6618882_ENST00000315579_length(transcript)=4770nt_BP=148nt
TTCCGGGGCGGATCGGAAGTTGCTTTGTTTTGCTTCGAGATGGCTGCGGGGATGTATTTGGAACATTATCTGGACAGTATTGAAAACCTT
CCCTTTGAATTACAGAGAAACTTTCAGCTCATGAGGGACCTAGACCAAAGAACAGAGGCTTTTCAGGCTGCCTTTCGAGCTCAGGGGCCC
CTGGCTATGCTGCAGCACTTTGATACTATCTACAGCATTTTGCATCACTTTCGAAGTATAGATCCTGGCCTCAAAGAAGATACTCTGCAA
TTCCTGATAAAAGTGGTATCCCGCCACTCCCAGGAGCTTCCAGCTATCCTGGATGATACAACTTTGAGTGGATCAGATAGAAACGCCCAT
CTAAATGCCCTCAAAATGAACTGTTATGCTCTGATACGTCTCCTGGAATCCTTTGAGACCATGGCCAGCCAGACAAACCTTGTGGACCTG
GACCTTGGTGGGAAGGGTAAGAAAGCTCGGACCAAGGCAGCCCATGGCTTTGACTGGGAAGAAGAGAGGCAACCAATTCTTCAGCTTTTA
ACACAGCTACTTCAGTTGGACATCCGTCACCTGTGGAACCACTCAATAATTGAAGAAGAATTTGTCAGTTTGGTTACTGGCTGTTGCTAC
CGCCTTCTGGAGAATCCCACCATTAATCACCAGAAGAACCGCCCCACTCGGGAAGCCATAACACACCTGCTTGGTGTAGCCTTGACCCGT
TATAACCATATGCTCAGTGCTACAGTGAAGATCATCCAGATGCTGCAGCACTTTGAACACCTGGCACCTGTACTGGTTGCAGCCGTGAGT
CTATGGGCAACTGACTATGGAATGAAGAGCATAGTGGGAGAGATTGTAAGAGAGATTGGACAAAAGTGTCCCCAAGAGCTGAGTCGAGAC
CCTTCAGGGACAAAGGGCTTTGCAGCATTCCTGACAGAACTAGCAGAACGTGTCCCAGCTATCCTGATGTCCAGCATGTGCATTTTGCTA
GATCACCTGGATGGAGAAAATTACATGATGCGTAATGCTGTGCTGGCAGCCATGGCGGAGATGGTGCTGCAGGTTCTCAGTGGCGATCAA
CTGGAAGCAGCAGCCCGAGACACCAGAGACCAGTTCTTGGATACTTTACAAGCCCATGGCCATGATGTCAACTCCTTTGTGCGGAGCCGT
GTTTTGCAGCTCTTCACCCGAATTGTCCAGCAGAAGGCTCTCCCCCTGACACGTTTCCAGGCAGTGGTGGCTTTAGCTGTGGGACGTCTG
GCAGACAAGTCAGTGCTAGTATGTAAAAATGCCATCCAGCTGCTGGCCAGTTTTCTAGCCAATAATCCTTTCTCCTGCAAGCTTAGTGAT
GCTGACCTTGCCGGACCACTGCAGAAGGAGACCCAGAAATTACAAGAGATGAGGGCCCAGAGGCGAACTGCAGCAGCTTCTGCAGTGCTG
GACCCAGAGGAGGAGTGGGAAGCCATGCTGCCAGAGTTGAAGTCTACCCTGCAGCAGCTTCTACAGCTTCCCCAGGGAGAGGAGGAGATT
CCTGAGCAAATTGCCAATACAGAGACAACTGAAGATGTGAAAGGACGCATCTATCAACTGCTTGCCAAAGCTAGTTACAAAAAGGCCATC
ATTCTCACTCGAGAAGCCACAGGCCACTTCCAGGAGTCCGAACCCTTCAGTCATATAGACCCAGAGGAGTCAGAGGAGACCAGGCTCTTG
AATATCTTAGGACTTATCTTCAAAGGCCCAGCAGCTTCCACACAAGAAAAGAATCCCCGGGAGTCTACAGGAAACATGGTCACAGGACAG
ACTGTCTGTAAAAATAAACCCAATATGTCGGATCCTGAGGAATCCAGGGGAAATGATGAACTAGTGAAGCAGGAGATGCTGGTACAGTAT
CTGCAGGATGCCTACAGCTTCTCCCGGAAGATTACAGAGGCCATTGGCATCATCAGCAAGATGATGTATGAAAACACAACTACAGTGGTG
CAGGAGGTGATTGAATTCTTTGTGATGGTCTTCCAATTTGGGGTACCCCAGGCCCTGTTTGGGGTGCGCCGTATGCTGCCTCTCATCTGG
TCTAAGGAGCCTGGTGTCCGGGAAGCCGTGCTTAATGCCTACCGCCAACTCTACCTCAACCCCAAAGGGGACTCTGCCAGAGCCAAGGCC
CAGGCTTTGATTCAGAATCTCTCTCTGCTGCTAGTGGATGCCTCGGTTGGGACCATTCAGTGTCTTGAGGAAATTCTCTGTGAGTTTGTG
CAGAAGGATGAGTTGAAACCAGCAGTGACCCAGCTGCTGTGGGAGCGGGCCACCGAGAAGGTCGCCTGCTGTCCTCTGGAGCGCTGTTCC
TCTGTCATGCTTCTTGGCATGATGGCACGAGGAAAGCCAGAAATTGTGGGAAGCAATTTAGACACACTGGTGAGCATAGGGCTGGATGAG
AAGTTTCCACAGGACTACAGGCTGGCCCAGCAGGTGTGCCATGCCATTGCCAACATCTCGGACAGGAGAAAGCCTTCTCTGGGCAAACGT
CACCCCCCCTTCCGGCTGCCTCAGGAACACAGGTTGTTTGAGCGACTGCGGGAGACAGTCACAAAAGGCTTTGTCCACCCAGACCCACTC
TGGATCCCATTCAAAGAGGTGGCAGTGACCCTCATTTACCAACTGGCAGAGGGCCCCGAAGTGATCTGTGCCCAGATATTGCAGGGCTGT
GCAAAACAGGCCCTGGAGAAGCTAGAAGAGAAGAGAACCAGTCAGGAGGACCCGAAGGAGTCCCCCGCAATGCTCCCCACTTTCCTGTTG
ATGAACCTGCTGTCCCTGGCTGGGGATGTGGCTCTGCAGCAGCTGGTCCACTTGGAGCAGGCAGTGAGTGGAGAGCTCTGCCGGCGCCGA
GTTCTCCGGGAAGAACAGGAGCACAAGACCAAAGATCCCAAGGAGAAGAATACGAGCTCTGAGACCACCATGGAGGAGGAGCTGGGGCTG
GTTGGGGCAACAGCAGATGACACAGAGGCAGAACTAATCCGTGGCATCTGCGAGATGGAACTGTTGGATGGCAAACAGACACTGGCTGCC
TTTGTTCCACTCTTGCTTAAAGTCTGTAACAACCCAGGCCTCTATAGCAACCCAGACCTCTCTGCAGCTGCTTCACTTGCCCTTGGCAAG
TTCTGCATGATCAGTGCCACTTTCTGCGACTCCCAGCTTCGTCTTCTGTTCACCATGCTGGAAAAGTCTCCACTTCCCATTGTCCGGTCT
AACCTCATGGTTGCCACTGGGGATCTGGCCATCCGCTTTCCCAATCTGGTGGACCCCTGGACTCCTCATCTGTATGCTCGTCTCCGGGAC
CCTGCTCAGCAAGTGCGGAAAACAGCGGGGCTGGTGATGACCCACCTGATCCTCAAGGACATGGTGAAGGTGAAGGGGCAGGTCAGCGAG
ATGGCGGTGCTGCTCATCGACCCCGAGCCTCAGATTGCTGCCCTGGCCAAGAACTTCTTCAATGAGCTCTCCCACAAGGGCAACGCAATC
TATAATCTCCTTCCAGATATCATCAGCCGCCTGTCAGACCCCGAGCTGGGGGTGGAGGAAGAGCCTTTCCACACCATCATGAAACAGCTC
CTCTCCTACATCACCAAGGACAAGCAGACAGAGAGCCTGGTGGAAAAGCTGTGTCAGCGGTTCCGCACATCCCGAACTGAGCGGCAGCAG
CGAGACCTGGCCTACTGTGTGTCACAGCTGCCCCTCACAGAGCGAGGCCTCCGTAAGATGCTTGACAATTTTGACTGTTTTGGAGACAAA
CTGTCAGATGAGTCCATCTTCAGTGCTTTTTTGTCAGTTGTAGGCAAGCTGCGACGTGGGGCCAAGCCTGAGGGCAAGGCTATAATAGAT
GAATTTGAGCAGAAGCTTCGGGCCTGTCATACCAGAGGTTTGGATGGAATCAAGGAGCTTGAGATTGGCCAAGCAGGTAGCCAGAGAGCG
CCATCAGCCAAGAAACCATCCACTGGTTCTAGGTACCAGCCTCTGGCTTCTACAGCCTCAGACAATGACTTTGTCACACCAGAGCCCCGC
CGTACTACCCGTCGGCATCCAAACACCCAGCAGCGAGCTTCCAAAAAGAAACCCAAAGTTGTCTTCTCAAGTGATGAGTCCAGTGAGGAA
GATCTTTCAGCAGAGATGACAGAAGACGAGACACCCAAGAAAACAACTCCCATTCTCAGAGCATCGGCTCGCAGGCACAGATCCTAGGAA
GTCTGTTCCTGTCCTCCCTGTGCAGGGTATCCTGTAGGGTGACCTGGAATTCGAATTCTGTTTCCCTTGTAAAATATTTGTCTGTCTCTT
TTTTTTAAAAAAAAAAAAGGCCGGGCACTGTGGCTCACGCCTGTAATCCCAGCACTTTGCGATACCAAGGCGGGTGGATAACCTGAGGTA
GGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATAAAAAATTAGCCGGGCGTATTGGCGTGCGCCTGTAA
TCCCAGCTACTCAAGAGGCTGAGGCAGGAGAATCGCCTGAACCCAGAGGCGGAGGTTGTAGTGAGCCGAAATCACACCATTGCACTCCAG
CTTGGGCAACAATAGCGAACCTCCATCTCAAATTAAAAAAAAAATGCCTACACGCTCTTTAAAATGCAAGGCTTTCTCTTAAATTAGCCT
AACTGAACTGCGTTGAGCTGCTTCAACTTTGGAATATATGTTTGCCAATCTCCTTGTTTTCTAATGAATAAATGTTTTTATATACTTTTA

>39747_39747_2_ING4-NCAPD2_ING4_chr12_6765892_ENST00000396807_NCAPD2_chr12_6618882_ENST00000315579_length(amino acids)=1400AA_BP=41
MFCFEMAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEAFQAAFRAQGPLAMLQHFDTIYSILHHFRSIDPGLKEDTLQFLIKVVSR
HSQELPAILDDTTLSGSDRNAHLNALKMNCYALIRLLESFETMASQTNLVDLDLGGKGKKARTKAAHGFDWEEERQPILQLLTQLLQLDI
RHLWNHSIIEEEFVSLVTGCCYRLLENPTINHQKNRPTREAITHLLGVALTRYNHMLSATVKIIQMLQHFEHLAPVLVAAVSLWATDYGM
KSIVGEIVREIGQKCPQELSRDPSGTKGFAAFLTELAERVPAILMSSMCILLDHLDGENYMMRNAVLAAMAEMVLQVLSGDQLEAAARDT
RDQFLDTLQAHGHDVNSFVRSRVLQLFTRIVQQKALPLTRFQAVVALAVGRLADKSVLVCKNAIQLLASFLANNPFSCKLSDADLAGPLQ
KETQKLQEMRAQRRTAAASAVLDPEEEWEAMLPELKSTLQQLLQLPQGEEEIPEQIANTETTEDVKGRIYQLLAKASYKKAIILTREATG
HFQESEPFSHIDPEESEETRLLNILGLIFKGPAASTQEKNPRESTGNMVTGQTVCKNKPNMSDPEESRGNDELVKQEMLVQYLQDAYSFS
RKITEAIGIISKMMYENTTTVVQEVIEFFVMVFQFGVPQALFGVRRMLPLIWSKEPGVREAVLNAYRQLYLNPKGDSARAKAQALIQNLS
LLLVDASVGTIQCLEEILCEFVQKDELKPAVTQLLWERATEKVACCPLERCSSVMLLGMMARGKPEIVGSNLDTLVSIGLDEKFPQDYRL
AQQVCHAIANISDRRKPSLGKRHPPFRLPQEHRLFERLRETVTKGFVHPDPLWIPFKEVAVTLIYQLAEGPEVICAQILQGCAKQALEKL
EEKRTSQEDPKESPAMLPTFLLMNLLSLAGDVALQQLVHLEQAVSGELCRRRVLREEQEHKTKDPKEKNTSSETTMEEELGLVGATADDT
EAELIRGICEMELLDGKQTLAAFVPLLLKVCNNPGLYSNPDLSAAASLALGKFCMISATFCDSQLRLLFTMLEKSPLPIVRSNLMVATGD
LAIRFPNLVDPWTPHLYARLRDPAQQVRKTAGLVMTHLILKDMVKVKGQVSEMAVLLIDPEPQIAALAKNFFNELSHKGNAIYNLLPDII
SRLSDPELGVEEEPFHTIMKQLLSYITKDKQTESLVEKLCQRFRTSRTERQQRDLAYCVSQLPLTERGLRKMLDNFDCFGDKLSDESIFS
AFLSVVGKLRRGAKPEGKAIIDEFEQKLRACHTRGLDGIKELEIGQAGSQRAPSAKKPSTGSRYQPLASTASDNDFVTPEPRRTTRRHPN

--------------------------------------------------------------
>39747_39747_3_ING4-NCAPD2_ING4_chr12_6765892_ENST00000412586_NCAPD2_chr12_6618882_ENST00000315579_length(transcript)=4731nt_BP=109nt
ATGGCTGCGGGGATGTATTTGGAACATTATCTGGACAGTATTGAAAACCTTCCCTTTGAATTACAGAGAAACTTTCAGCTCATGAGGGAC
CTAGACCAAAGAACAGAGGCTTTTCAGGCTGCCTTTCGAGCTCAGGGGCCCCTGGCTATGCTGCAGCACTTTGATACTATCTACAGCATT
TTGCATCACTTTCGAAGTATAGATCCTGGCCTCAAAGAAGATACTCTGCAATTCCTGATAAAAGTGGTATCCCGCCACTCCCAGGAGCTT
CCAGCTATCCTGGATGATACAACTTTGAGTGGATCAGATAGAAACGCCCATCTAAATGCCCTCAAAATGAACTGTTATGCTCTGATACGT
CTCCTGGAATCCTTTGAGACCATGGCCAGCCAGACAAACCTTGTGGACCTGGACCTTGGTGGGAAGGGTAAGAAAGCTCGGACCAAGGCA
GCCCATGGCTTTGACTGGGAAGAAGAGAGGCAACCAATTCTTCAGCTTTTAACACAGCTACTTCAGTTGGACATCCGTCACCTGTGGAAC
CACTCAATAATTGAAGAAGAATTTGTCAGTTTGGTTACTGGCTGTTGCTACCGCCTTCTGGAGAATCCCACCATTAATCACCAGAAGAAC
CGCCCCACTCGGGAAGCCATAACACACCTGCTTGGTGTAGCCTTGACCCGTTATAACCATATGCTCAGTGCTACAGTGAAGATCATCCAG
ATGCTGCAGCACTTTGAACACCTGGCACCTGTACTGGTTGCAGCCGTGAGTCTATGGGCAACTGACTATGGAATGAAGAGCATAGTGGGA
GAGATTGTAAGAGAGATTGGACAAAAGTGTCCCCAAGAGCTGAGTCGAGACCCTTCAGGGACAAAGGGCTTTGCAGCATTCCTGACAGAA
CTAGCAGAACGTGTCCCAGCTATCCTGATGTCCAGCATGTGCATTTTGCTAGATCACCTGGATGGAGAAAATTACATGATGCGTAATGCT
GTGCTGGCAGCCATGGCGGAGATGGTGCTGCAGGTTCTCAGTGGCGATCAACTGGAAGCAGCAGCCCGAGACACCAGAGACCAGTTCTTG
GATACTTTACAAGCCCATGGCCATGATGTCAACTCCTTTGTGCGGAGCCGTGTTTTGCAGCTCTTCACCCGAATTGTCCAGCAGAAGGCT
CTCCCCCTGACACGTTTCCAGGCAGTGGTGGCTTTAGCTGTGGGACGTCTGGCAGACAAGTCAGTGCTAGTATGTAAAAATGCCATCCAG
CTGCTGGCCAGTTTTCTAGCCAATAATCCTTTCTCCTGCAAGCTTAGTGATGCTGACCTTGCCGGACCACTGCAGAAGGAGACCCAGAAA
TTACAAGAGATGAGGGCCCAGAGGCGAACTGCAGCAGCTTCTGCAGTGCTGGACCCAGAGGAGGAGTGGGAAGCCATGCTGCCAGAGTTG
AAGTCTACCCTGCAGCAGCTTCTACAGCTTCCCCAGGGAGAGGAGGAGATTCCTGAGCAAATTGCCAATACAGAGACAACTGAAGATGTG
AAAGGACGCATCTATCAACTGCTTGCCAAAGCTAGTTACAAAAAGGCCATCATTCTCACTCGAGAAGCCACAGGCCACTTCCAGGAGTCC
GAACCCTTCAGTCATATAGACCCAGAGGAGTCAGAGGAGACCAGGCTCTTGAATATCTTAGGACTTATCTTCAAAGGCCCAGCAGCTTCC
ACACAAGAAAAGAATCCCCGGGAGTCTACAGGAAACATGGTCACAGGACAGACTGTCTGTAAAAATAAACCCAATATGTCGGATCCTGAG
GAATCCAGGGGAAATGATGAACTAGTGAAGCAGGAGATGCTGGTACAGTATCTGCAGGATGCCTACAGCTTCTCCCGGAAGATTACAGAG
GCCATTGGCATCATCAGCAAGATGATGTATGAAAACACAACTACAGTGGTGCAGGAGGTGATTGAATTCTTTGTGATGGTCTTCCAATTT
GGGGTACCCCAGGCCCTGTTTGGGGTGCGCCGTATGCTGCCTCTCATCTGGTCTAAGGAGCCTGGTGTCCGGGAAGCCGTGCTTAATGCC
TACCGCCAACTCTACCTCAACCCCAAAGGGGACTCTGCCAGAGCCAAGGCCCAGGCTTTGATTCAGAATCTCTCTCTGCTGCTAGTGGAT
GCCTCGGTTGGGACCATTCAGTGTCTTGAGGAAATTCTCTGTGAGTTTGTGCAGAAGGATGAGTTGAAACCAGCAGTGACCCAGCTGCTG
TGGGAGCGGGCCACCGAGAAGGTCGCCTGCTGTCCTCTGGAGCGCTGTTCCTCTGTCATGCTTCTTGGCATGATGGCACGAGGAAAGCCA
GAAATTGTGGGAAGCAATTTAGACACACTGGTGAGCATAGGGCTGGATGAGAAGTTTCCACAGGACTACAGGCTGGCCCAGCAGGTGTGC
CATGCCATTGCCAACATCTCGGACAGGAGAAAGCCTTCTCTGGGCAAACGTCACCCCCCCTTCCGGCTGCCTCAGGAACACAGGTTGTTT
GAGCGACTGCGGGAGACAGTCACAAAAGGCTTTGTCCACCCAGACCCACTCTGGATCCCATTCAAAGAGGTGGCAGTGACCCTCATTTAC
CAACTGGCAGAGGGCCCCGAAGTGATCTGTGCCCAGATATTGCAGGGCTGTGCAAAACAGGCCCTGGAGAAGCTAGAAGAGAAGAGAACC
AGTCAGGAGGACCCGAAGGAGTCCCCCGCAATGCTCCCCACTTTCCTGTTGATGAACCTGCTGTCCCTGGCTGGGGATGTGGCTCTGCAG
CAGCTGGTCCACTTGGAGCAGGCAGTGAGTGGAGAGCTCTGCCGGCGCCGAGTTCTCCGGGAAGAACAGGAGCACAAGACCAAAGATCCC
AAGGAGAAGAATACGAGCTCTGAGACCACCATGGAGGAGGAGCTGGGGCTGGTTGGGGCAACAGCAGATGACACAGAGGCAGAACTAATC
CGTGGCATCTGCGAGATGGAACTGTTGGATGGCAAACAGACACTGGCTGCCTTTGTTCCACTCTTGCTTAAAGTCTGTAACAACCCAGGC
CTCTATAGCAACCCAGACCTCTCTGCAGCTGCTTCACTTGCCCTTGGCAAGTTCTGCATGATCAGTGCCACTTTCTGCGACTCCCAGCTT
CGTCTTCTGTTCACCATGCTGGAAAAGTCTCCACTTCCCATTGTCCGGTCTAACCTCATGGTTGCCACTGGGGATCTGGCCATCCGCTTT
CCCAATCTGGTGGACCCCTGGACTCCTCATCTGTATGCTCGTCTCCGGGACCCTGCTCAGCAAGTGCGGAAAACAGCGGGGCTGGTGATG
ACCCACCTGATCCTCAAGGACATGGTGAAGGTGAAGGGGCAGGTCAGCGAGATGGCGGTGCTGCTCATCGACCCCGAGCCTCAGATTGCT
GCCCTGGCCAAGAACTTCTTCAATGAGCTCTCCCACAAGGGCAACGCAATCTATAATCTCCTTCCAGATATCATCAGCCGCCTGTCAGAC
CCCGAGCTGGGGGTGGAGGAAGAGCCTTTCCACACCATCATGAAACAGCTCCTCTCCTACATCACCAAGGACAAGCAGACAGAGAGCCTG
GTGGAAAAGCTGTGTCAGCGGTTCCGCACATCCCGAACTGAGCGGCAGCAGCGAGACCTGGCCTACTGTGTGTCACAGCTGCCCCTCACA
GAGCGAGGCCTCCGTAAGATGCTTGACAATTTTGACTGTTTTGGAGACAAACTGTCAGATGAGTCCATCTTCAGTGCTTTTTTGTCAGTT
GTAGGCAAGCTGCGACGTGGGGCCAAGCCTGAGGGCAAGGCTATAATAGATGAATTTGAGCAGAAGCTTCGGGCCTGTCATACCAGAGGT
TTGGATGGAATCAAGGAGCTTGAGATTGGCCAAGCAGGTAGCCAGAGAGCGCCATCAGCCAAGAAACCATCCACTGGTTCTAGGTACCAG
CCTCTGGCTTCTACAGCCTCAGACAATGACTTTGTCACACCAGAGCCCCGCCGTACTACCCGTCGGCATCCAAACACCCAGCAGCGAGCT
TCCAAAAAGAAACCCAAAGTTGTCTTCTCAAGTGATGAGTCCAGTGAGGAAGATCTTTCAGCAGAGATGACAGAAGACGAGACACCCAAG
AAAACAACTCCCATTCTCAGAGCATCGGCTCGCAGGCACAGATCCTAGGAAGTCTGTTCCTGTCCTCCCTGTGCAGGGTATCCTGTAGGG
TGACCTGGAATTCGAATTCTGTTTCCCTTGTAAAATATTTGTCTGTCTCTTTTTTTTAAAAAAAAAAAAGGCCGGGCACTGTGGCTCACG
CCTGTAATCCCAGCACTTTGCGATACCAAGGCGGGTGGATAACCTGAGGTAGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCCC
ATCTCTACTAAAAATAAAAAATTAGCCGGGCGTATTGGCGTGCGCCTGTAATCCCAGCTACTCAAGAGGCTGAGGCAGGAGAATCGCCTG
AACCCAGAGGCGGAGGTTGTAGTGAGCCGAAATCACACCATTGCACTCCAGCTTGGGCAACAATAGCGAACCTCCATCTCAAATTAAAAA
AAAAATGCCTACACGCTCTTTAAAATGCAAGGCTTTCTCTTAAATTAGCCTAACTGAACTGCGTTGAGCTGCTTCAACTTTGGAATATAT

>39747_39747_3_ING4-NCAPD2_ING4_chr12_6765892_ENST00000412586_NCAPD2_chr12_6618882_ENST00000315579_length(amino acids)=1395AA_BP=36
MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEAFQAAFRAQGPLAMLQHFDTIYSILHHFRSIDPGLKEDTLQFLIKVVSRHSQEL
PAILDDTTLSGSDRNAHLNALKMNCYALIRLLESFETMASQTNLVDLDLGGKGKKARTKAAHGFDWEEERQPILQLLTQLLQLDIRHLWN
HSIIEEEFVSLVTGCCYRLLENPTINHQKNRPTREAITHLLGVALTRYNHMLSATVKIIQMLQHFEHLAPVLVAAVSLWATDYGMKSIVG
EIVREIGQKCPQELSRDPSGTKGFAAFLTELAERVPAILMSSMCILLDHLDGENYMMRNAVLAAMAEMVLQVLSGDQLEAAARDTRDQFL
DTLQAHGHDVNSFVRSRVLQLFTRIVQQKALPLTRFQAVVALAVGRLADKSVLVCKNAIQLLASFLANNPFSCKLSDADLAGPLQKETQK
LQEMRAQRRTAAASAVLDPEEEWEAMLPELKSTLQQLLQLPQGEEEIPEQIANTETTEDVKGRIYQLLAKASYKKAIILTREATGHFQES
EPFSHIDPEESEETRLLNILGLIFKGPAASTQEKNPRESTGNMVTGQTVCKNKPNMSDPEESRGNDELVKQEMLVQYLQDAYSFSRKITE
AIGIISKMMYENTTTVVQEVIEFFVMVFQFGVPQALFGVRRMLPLIWSKEPGVREAVLNAYRQLYLNPKGDSARAKAQALIQNLSLLLVD
ASVGTIQCLEEILCEFVQKDELKPAVTQLLWERATEKVACCPLERCSSVMLLGMMARGKPEIVGSNLDTLVSIGLDEKFPQDYRLAQQVC
HAIANISDRRKPSLGKRHPPFRLPQEHRLFERLRETVTKGFVHPDPLWIPFKEVAVTLIYQLAEGPEVICAQILQGCAKQALEKLEEKRT
SQEDPKESPAMLPTFLLMNLLSLAGDVALQQLVHLEQAVSGELCRRRVLREEQEHKTKDPKEKNTSSETTMEEELGLVGATADDTEAELI
RGICEMELLDGKQTLAAFVPLLLKVCNNPGLYSNPDLSAAASLALGKFCMISATFCDSQLRLLFTMLEKSPLPIVRSNLMVATGDLAIRF
PNLVDPWTPHLYARLRDPAQQVRKTAGLVMTHLILKDMVKVKGQVSEMAVLLIDPEPQIAALAKNFFNELSHKGNAIYNLLPDIISRLSD
PELGVEEEPFHTIMKQLLSYITKDKQTESLVEKLCQRFRTSRTERQQRDLAYCVSQLPLTERGLRKMLDNFDCFGDKLSDESIFSAFLSV
VGKLRRGAKPEGKAIIDEFEQKLRACHTRGLDGIKELEIGQAGSQRAPSAKKPSTGSRYQPLASTASDNDFVTPEPRRTTRRHPNTQQRA

--------------------------------------------------------------
>39747_39747_4_ING4-NCAPD2_ING4_chr12_6765892_ENST00000423703_NCAPD2_chr12_6618882_ENST00000545962_length(transcript)=4193nt_BP=109nt
ATGGCTGCGGGGATGTATTTGGAACATTATCTGGACAGTATTGAAAACCTTCCCTTTGAATTACAGAGAAACTTTCAGCTCATGAGGGAC
CTAGACCAAAGAACAGAGGCTTTTCAGGCTGCCTTTCGAGCTCAGGGGCCCCTGGCTATGCTGCAGCACTTTGATACTATCTACAGCATT
TTGCATGGTATCCCGCCACTCCCAGGAGCTTCCAGCTATCCTGGATGATACAACTTTGAGTGGATCAGATAGAAACGCCCATCTAAATGC
CCTCAAAATGAACTGTTATGCTCTGATACGTCTCCTGGAATCCTTTGAGACCATGGCCAGCCAGACAAACCTTGTGGACCTGGACCTTGG
TGGGAAGGGTAAGAAAGCTCGGACCAAGGCAGCCCATGGCTTTGACTGGGAAGAAGAGAGGCAACCAATTCTTCAGCTTTTAACACAGCT
ACTTCAGTTGGACATCCGTCACCTGTGGAACCACTCAATAATTGAAGAAGAATTTGTCAGTTTGGTTACTGGCTGTTGCTACCGCCTTCT
GGAGAATCCCACCATTAATCACCAGAAGAACCGCCCCACTCGGGAAGCCATAACACACCTGCTTGGTGTAGCCTTGACCCGTTATAACCA
TATGCTCAGTGCTACAGTGAAGATCATCCAGATGCTGCAGCACTTTGAACACCTGGCACCTGTACTGGTTGCAGCCGTGAGTCTATGGGC
AACTGACTATGGAATGAAGAGCATAGTGGGAGAGATTGTAAGAGAGATTGGACAAAAGTGTCCCCAAGAGCTGAGTCGAGACCCTTCAGG
GACAAAGGGCTTTGCAGCATTCCTGACAGAACTAGCAGAACGTGTCCCAGCTATCCTGATGTCCAGCATGTGCATTTTGCTAGATCACCT
GGATGGAGAAAATTACATGATGCGTAATGCTGTGCTGGCAGCCATGGCGGAGATGGTGCTGCAGGTTCTCAGTGGCGATCAACTGGAAGC
AGCAGCCCGAGACACCAGAGACCAGTTCTTGGATACTTTACAAGCCCATGGCCATGATGTCAACTCCTTTGTGCGGAGCCGTGTTTTGCA
GCTCTTCACCCGAATTGTCCAGCAGAAGGCTCTCCCCCTGACACGTTTCCAGGCAGTGGTGGCTTTAGCTGTGGGACGTCTGGCAGACAA
GTCAGTGCTAGTATGTAAAAATGCCATCCAGCTGCTGGCCAGTTTTCTAGCCAATAATCCTTTCTCCTGCAAGCTTAGTGATGCTGACCT
TGCCGGACCACTGCAGAAGGAGACCCAGAAATTACAAGAGATGAGGGCCCAGAGGCGAACTGCAGCAGCTTCTGCAGTGCTGGACCCAGA
GGAGGAGTGGGAAGCCATGCTGCCAGAGTTGAAGTCTACCCTGCAGCAGCTTCTACAGCTTCCCCAGGGAGAGGAGGAGATTCCTGAGCA
AATTGCCAATACAGAGACAACTGAAGATGTGAAAGGACGCATCTATCAACTGCTTGCCAAAGCTAGTTACAAAAAGGCCATCATTCTCAC
TCGAGAAGCCACAGGCCACTTCCAGGAGTCCGAACCCTTCAGTCATATAGACCCAGAGGAGTCAGAGGAGACCAGGCTCTTGAATATCTT
AGGACTTATCTTCAAAGGCCCAGCAGCTTCCACACAAGAAAAGAATCCCCGGGAGTCTACAGGAAACATGGTCACAGGACAGACTGTCTG
TAAAAATAAACCCAATATGTCGGATCCTGAGGAATCCAGGGGAAATGATGAACTAGTGAAGCAGGAGATGCTGGTACAGTATCTGCAGGA
TGCCTACAGCTTCTCCCGGAAGATTACAGAGGCCATTGGCATCATCAGCAAGATGATGTATGAAAACACAACTACAGTGGTGCAGGAGGT
GATTGAATTCTTTGTGATGGTCTTCCAATTTGGGGTACCCCAGGCCCTGTTTGGGGTGCGCCGTATGCTGCCTCTCATCTGGTCTAAGGA
GCCTGGTGTCCGGGAAGCCGTGCTTAATGCCTACCGCCAACTCTACCTCAACCCCAAAGGGGACTCTGCCAGAGCCAAGGCCCAGGCTTT
GATTCAGAATCTCTCTCTGCTGCTAGTGGATGCCTCGGTTGGGACCATTCAGTGTCTTGAGGAAATTCTCTGTGAGTTTGTGCAGAAGGA
TGAGTTGAAACCAGCAGTGACCCAGCTGCTGTGGGAGCGGGCCACCGAGAAGGTCGCCTGCTGTCCTCTGGAGCGCTGTTCCTCTGTCAT
GCTTCTTGGCATGATGGCACGAGGAAAGCCAGAAATTGTGGGAAGCAATTTAGACACACTGGTGAGCATAGGGCTGGATGAGAAGTTTCC
ACAGGACTACAGGCTGGCCCAGCAGGTGTGCCATGCCATTGCCAACATCTCGGACAGGAGAAAGCCTTCTCTGGGCAAACGTCACCCCCC
CTTCCGGCTGCCTCAGGAACACAGGTTGTTTGAGCGACTGCGGGAGACAGTCACAAAAGGCTTTGTCCACCCAGACCCACTCTGGATCCC
ATTCAAAGAGGTGGCAGTGACCCTCATTTACCAACTGGCAGAGGGCCCCGAAGTGATCTGTGCCCAGATATTGCAGGGCTGTGCAAAACA
GGCCCTGGAGAAGCTAGAAGAGAAGAGAACCAGTCAGGAGGACCCGAAGGAGTCCCCCGCAATGCTCCCCACTTTCCTGTTGATGAACCT
GCTGTCCCTGGCTGGGGATGTGGCTCTGCAGCAGCTGGTCCACTTGGAGCAGGCAGTGAGTGGAGAGCTCTGCCGGCGCCGAGTTCTCCG
GGAAGAACAGGAGCACAAGACCAAAGATCCCAAGGAGAAGAATACGAGCTCTGAGACCACCATGGAGGAGGAGCTGGGGCTGGTTGGGGC
AACAGCAGATGACACAGAGGCAGAACTAATCCGTGGCATCTGCGAGATGGAACTGTTGGATGGCAAACAGACACTGGCTGCCTTTGTTCC
ACTCTTGCTTAAAGTCTGTAACAACCCAGGCCTCTATAGCAACCCAGACCTCTCTGCAGCTGCTTCACTTGCCCTTGGCAAGTTCTGCAT
GATCAGTGCCACTTTCTGCGACTCCCAGCTTCGTCTTCTGTTCACCATGCTGGAAAAGTCTCCACTTCCCATTGTCCGGTCTAACCTCAT
GGTTGCCACTGGGGATCTGGCCATCCGCTTTCCCAATCTGGTGGACCCCTGGACTCCTCATCTGTATGCTCGTCTCCGGGACCCTGCTCA
GCAAGTGCGGAAAACAGCGGGGCTGGTGATGACCCACCTGATCCTCAAGGACATGGTGAAGGTGAAGGGGCAGGTCAGCGAGATGGCGGT
GCTGCTCATCGACCCCGAGCCTCAGATTGCTGCCCTGGCCAAGAACTTCTTCAATGAGCTCTCCCACAAGGGCAACGCAATCTATAATCT
CCTTCCAGATATCATCAGCCGCCTGTCAGACCCCGAGCTGGGGGTGGAGGAAGAGCCTTTCCACACCATCATGAAACAGCTCCTCTCCTA
CATCACCAAGGACAAGCAGACAGAGAGCCTGGTGGAAAAGCTGTGTCAGCGGTTCCGCACATCCCGAACTGAGCGGCAGCAGCGAGACCT
GGCCTACTGTGTGTCACAGCTGCCCCTCACAGAGCGAGGCCTCCGTAAGATGCTTGACAATTTTGACTGTTTTGGAGACAAACTGTCAGA
TGAGTCCATCTTCAGTGCTTTTTTGTCAGTTGTAGGCAAGCTGCGACGTGGGGCCAAGCCTGAGGGCAAGGCTATAATAGATGAATTTGA
GCAGAAGCTTCGGGCCTGTCATACCAGAGGTTTGGATGGAATCAAGGAGCTTGAGATTGGCCAAGCAGGTAGCCAGAGAGCGCCATCAGC
CAAGAAACCATCCACTGGTTCTAGGTACCAGCCTCTGGCTTCTACAGCCTCAGACAATGACTTTGTCACACCAGAGCCCCGCCGTACTAC
CCGTCGGCATCCAAACACCCAGCAGCGAGCTTCCAAAAAGAAACCCAAAGTTGTCTTCTCAAGTGATGAGTCCAGTGAGGAAGATCTTTC
AGCAGAGATGACAGAAGACGAGACACCCAAGAAAACAACTCCCATTCTCAGAGCATCGGCTCGCAGGCACAGATCCTAGGAAGTCTGTTC

>39747_39747_4_ING4-NCAPD2_ING4_chr12_6765892_ENST00000423703_NCAPD2_chr12_6618882_ENST00000545962_length(amino acids)=1336AA_BP=
MPFELRGPWLCCSTLILSTAFCMVSRHSQELPAILDDTTLSGSDRNAHLNALKMNCYALIRLLESFETMASQTNLVDLDLGGKGKKARTK
AAHGFDWEEERQPILQLLTQLLQLDIRHLWNHSIIEEEFVSLVTGCCYRLLENPTINHQKNRPTREAITHLLGVALTRYNHMLSATVKII
QMLQHFEHLAPVLVAAVSLWATDYGMKSIVGEIVREIGQKCPQELSRDPSGTKGFAAFLTELAERVPAILMSSMCILLDHLDGENYMMRN
AVLAAMAEMVLQVLSGDQLEAAARDTRDQFLDTLQAHGHDVNSFVRSRVLQLFTRIVQQKALPLTRFQAVVALAVGRLADKSVLVCKNAI
QLLASFLANNPFSCKLSDADLAGPLQKETQKLQEMRAQRRTAAASAVLDPEEEWEAMLPELKSTLQQLLQLPQGEEEIPEQIANTETTED
VKGRIYQLLAKASYKKAIILTREATGHFQESEPFSHIDPEESEETRLLNILGLIFKGPAASTQEKNPRESTGNMVTGQTVCKNKPNMSDP
EESRGNDELVKQEMLVQYLQDAYSFSRKITEAIGIISKMMYENTTTVVQEVIEFFVMVFQFGVPQALFGVRRMLPLIWSKEPGVREAVLN
AYRQLYLNPKGDSARAKAQALIQNLSLLLVDASVGTIQCLEEILCEFVQKDELKPAVTQLLWERATEKVACCPLERCSSVMLLGMMARGK
PEIVGSNLDTLVSIGLDEKFPQDYRLAQQVCHAIANISDRRKPSLGKRHPPFRLPQEHRLFERLRETVTKGFVHPDPLWIPFKEVAVTLI
YQLAEGPEVICAQILQGCAKQALEKLEEKRTSQEDPKESPAMLPTFLLMNLLSLAGDVALQQLVHLEQAVSGELCRRRVLREEQEHKTKD
PKEKNTSSETTMEEELGLVGATADDTEAELIRGICEMELLDGKQTLAAFVPLLLKVCNNPGLYSNPDLSAAASLALGKFCMISATFCDSQ
LRLLFTMLEKSPLPIVRSNLMVATGDLAIRFPNLVDPWTPHLYARLRDPAQQVRKTAGLVMTHLILKDMVKVKGQVSEMAVLLIDPEPQI
AALAKNFFNELSHKGNAIYNLLPDIISRLSDPELGVEEEPFHTIMKQLLSYITKDKQTESLVEKLCQRFRTSRTERQQRDLAYCVSQLPL
TERGLRKMLDNFDCFGDKLSDESIFSAFLSVVGKLRRGAKPEGKAIIDEFEQKLRACHTRGLDGIKELEIGQAGSQRAPSAKKPSTGSRY

--------------------------------------------------------------
>39747_39747_5_ING4-NCAPD2_ING4_chr12_6765892_ENST00000446105_NCAPD2_chr12_6618882_ENST00000315579_length(transcript)=4772nt_BP=150nt
ACTTCCGGGGCGGATCGGAAGTTGCTTTGTTTTGCTTCGAGATGGCTGCGGGGATGTATTTGGAACATTATCTGGACAGTATTGAAAACC
TTCCCTTTGAATTACAGAGAAACTTTCAGCTCATGAGGGACCTAGACCAAAGAACAGAGGCTTTTCAGGCTGCCTTTCGAGCTCAGGGGC
CCCTGGCTATGCTGCAGCACTTTGATACTATCTACAGCATTTTGCATCACTTTCGAAGTATAGATCCTGGCCTCAAAGAAGATACTCTGC
AATTCCTGATAAAAGTGGTATCCCGCCACTCCCAGGAGCTTCCAGCTATCCTGGATGATACAACTTTGAGTGGATCAGATAGAAACGCCC
ATCTAAATGCCCTCAAAATGAACTGTTATGCTCTGATACGTCTCCTGGAATCCTTTGAGACCATGGCCAGCCAGACAAACCTTGTGGACC
TGGACCTTGGTGGGAAGGGTAAGAAAGCTCGGACCAAGGCAGCCCATGGCTTTGACTGGGAAGAAGAGAGGCAACCAATTCTTCAGCTTT
TAACACAGCTACTTCAGTTGGACATCCGTCACCTGTGGAACCACTCAATAATTGAAGAAGAATTTGTCAGTTTGGTTACTGGCTGTTGCT
ACCGCCTTCTGGAGAATCCCACCATTAATCACCAGAAGAACCGCCCCACTCGGGAAGCCATAACACACCTGCTTGGTGTAGCCTTGACCC
GTTATAACCATATGCTCAGTGCTACAGTGAAGATCATCCAGATGCTGCAGCACTTTGAACACCTGGCACCTGTACTGGTTGCAGCCGTGA
GTCTATGGGCAACTGACTATGGAATGAAGAGCATAGTGGGAGAGATTGTAAGAGAGATTGGACAAAAGTGTCCCCAAGAGCTGAGTCGAG
ACCCTTCAGGGACAAAGGGCTTTGCAGCATTCCTGACAGAACTAGCAGAACGTGTCCCAGCTATCCTGATGTCCAGCATGTGCATTTTGC
TAGATCACCTGGATGGAGAAAATTACATGATGCGTAATGCTGTGCTGGCAGCCATGGCGGAGATGGTGCTGCAGGTTCTCAGTGGCGATC
AACTGGAAGCAGCAGCCCGAGACACCAGAGACCAGTTCTTGGATACTTTACAAGCCCATGGCCATGATGTCAACTCCTTTGTGCGGAGCC
GTGTTTTGCAGCTCTTCACCCGAATTGTCCAGCAGAAGGCTCTCCCCCTGACACGTTTCCAGGCAGTGGTGGCTTTAGCTGTGGGACGTC
TGGCAGACAAGTCAGTGCTAGTATGTAAAAATGCCATCCAGCTGCTGGCCAGTTTTCTAGCCAATAATCCTTTCTCCTGCAAGCTTAGTG
ATGCTGACCTTGCCGGACCACTGCAGAAGGAGACCCAGAAATTACAAGAGATGAGGGCCCAGAGGCGAACTGCAGCAGCTTCTGCAGTGC
TGGACCCAGAGGAGGAGTGGGAAGCCATGCTGCCAGAGTTGAAGTCTACCCTGCAGCAGCTTCTACAGCTTCCCCAGGGAGAGGAGGAGA
TTCCTGAGCAAATTGCCAATACAGAGACAACTGAAGATGTGAAAGGACGCATCTATCAACTGCTTGCCAAAGCTAGTTACAAAAAGGCCA
TCATTCTCACTCGAGAAGCCACAGGCCACTTCCAGGAGTCCGAACCCTTCAGTCATATAGACCCAGAGGAGTCAGAGGAGACCAGGCTCT
TGAATATCTTAGGACTTATCTTCAAAGGCCCAGCAGCTTCCACACAAGAAAAGAATCCCCGGGAGTCTACAGGAAACATGGTCACAGGAC
AGACTGTCTGTAAAAATAAACCCAATATGTCGGATCCTGAGGAATCCAGGGGAAATGATGAACTAGTGAAGCAGGAGATGCTGGTACAGT
ATCTGCAGGATGCCTACAGCTTCTCCCGGAAGATTACAGAGGCCATTGGCATCATCAGCAAGATGATGTATGAAAACACAACTACAGTGG
TGCAGGAGGTGATTGAATTCTTTGTGATGGTCTTCCAATTTGGGGTACCCCAGGCCCTGTTTGGGGTGCGCCGTATGCTGCCTCTCATCT
GGTCTAAGGAGCCTGGTGTCCGGGAAGCCGTGCTTAATGCCTACCGCCAACTCTACCTCAACCCCAAAGGGGACTCTGCCAGAGCCAAGG
CCCAGGCTTTGATTCAGAATCTCTCTCTGCTGCTAGTGGATGCCTCGGTTGGGACCATTCAGTGTCTTGAGGAAATTCTCTGTGAGTTTG
TGCAGAAGGATGAGTTGAAACCAGCAGTGACCCAGCTGCTGTGGGAGCGGGCCACCGAGAAGGTCGCCTGCTGTCCTCTGGAGCGCTGTT
CCTCTGTCATGCTTCTTGGCATGATGGCACGAGGAAAGCCAGAAATTGTGGGAAGCAATTTAGACACACTGGTGAGCATAGGGCTGGATG
AGAAGTTTCCACAGGACTACAGGCTGGCCCAGCAGGTGTGCCATGCCATTGCCAACATCTCGGACAGGAGAAAGCCTTCTCTGGGCAAAC
GTCACCCCCCCTTCCGGCTGCCTCAGGAACACAGGTTGTTTGAGCGACTGCGGGAGACAGTCACAAAAGGCTTTGTCCACCCAGACCCAC
TCTGGATCCCATTCAAAGAGGTGGCAGTGACCCTCATTTACCAACTGGCAGAGGGCCCCGAAGTGATCTGTGCCCAGATATTGCAGGGCT
GTGCAAAACAGGCCCTGGAGAAGCTAGAAGAGAAGAGAACCAGTCAGGAGGACCCGAAGGAGTCCCCCGCAATGCTCCCCACTTTCCTGT
TGATGAACCTGCTGTCCCTGGCTGGGGATGTGGCTCTGCAGCAGCTGGTCCACTTGGAGCAGGCAGTGAGTGGAGAGCTCTGCCGGCGCC
GAGTTCTCCGGGAAGAACAGGAGCACAAGACCAAAGATCCCAAGGAGAAGAATACGAGCTCTGAGACCACCATGGAGGAGGAGCTGGGGC
TGGTTGGGGCAACAGCAGATGACACAGAGGCAGAACTAATCCGTGGCATCTGCGAGATGGAACTGTTGGATGGCAAACAGACACTGGCTG
CCTTTGTTCCACTCTTGCTTAAAGTCTGTAACAACCCAGGCCTCTATAGCAACCCAGACCTCTCTGCAGCTGCTTCACTTGCCCTTGGCA
AGTTCTGCATGATCAGTGCCACTTTCTGCGACTCCCAGCTTCGTCTTCTGTTCACCATGCTGGAAAAGTCTCCACTTCCCATTGTCCGGT
CTAACCTCATGGTTGCCACTGGGGATCTGGCCATCCGCTTTCCCAATCTGGTGGACCCCTGGACTCCTCATCTGTATGCTCGTCTCCGGG
ACCCTGCTCAGCAAGTGCGGAAAACAGCGGGGCTGGTGATGACCCACCTGATCCTCAAGGACATGGTGAAGGTGAAGGGGCAGGTCAGCG
AGATGGCGGTGCTGCTCATCGACCCCGAGCCTCAGATTGCTGCCCTGGCCAAGAACTTCTTCAATGAGCTCTCCCACAAGGGCAACGCAA
TCTATAATCTCCTTCCAGATATCATCAGCCGCCTGTCAGACCCCGAGCTGGGGGTGGAGGAAGAGCCTTTCCACACCATCATGAAACAGC
TCCTCTCCTACATCACCAAGGACAAGCAGACAGAGAGCCTGGTGGAAAAGCTGTGTCAGCGGTTCCGCACATCCCGAACTGAGCGGCAGC
AGCGAGACCTGGCCTACTGTGTGTCACAGCTGCCCCTCACAGAGCGAGGCCTCCGTAAGATGCTTGACAATTTTGACTGTTTTGGAGACA
AACTGTCAGATGAGTCCATCTTCAGTGCTTTTTTGTCAGTTGTAGGCAAGCTGCGACGTGGGGCCAAGCCTGAGGGCAAGGCTATAATAG
ATGAATTTGAGCAGAAGCTTCGGGCCTGTCATACCAGAGGTTTGGATGGAATCAAGGAGCTTGAGATTGGCCAAGCAGGTAGCCAGAGAG
CGCCATCAGCCAAGAAACCATCCACTGGTTCTAGGTACCAGCCTCTGGCTTCTACAGCCTCAGACAATGACTTTGTCACACCAGAGCCCC
GCCGTACTACCCGTCGGCATCCAAACACCCAGCAGCGAGCTTCCAAAAAGAAACCCAAAGTTGTCTTCTCAAGTGATGAGTCCAGTGAGG
AAGATCTTTCAGCAGAGATGACAGAAGACGAGACACCCAAGAAAACAACTCCCATTCTCAGAGCATCGGCTCGCAGGCACAGATCCTAGG
AAGTCTGTTCCTGTCCTCCCTGTGCAGGGTATCCTGTAGGGTGACCTGGAATTCGAATTCTGTTTCCCTTGTAAAATATTTGTCTGTCTC
TTTTTTTTAAAAAAAAAAAAGGCCGGGCACTGTGGCTCACGCCTGTAATCCCAGCACTTTGCGATACCAAGGCGGGTGGATAACCTGAGG
TAGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATAAAAAATTAGCCGGGCGTATTGGCGTGCGCCTGT
AATCCCAGCTACTCAAGAGGCTGAGGCAGGAGAATCGCCTGAACCCAGAGGCGGAGGTTGTAGTGAGCCGAAATCACACCATTGCACTCC
AGCTTGGGCAACAATAGCGAACCTCCATCTCAAATTAAAAAAAAAATGCCTACACGCTCTTTAAAATGCAAGGCTTTCTCTTAAATTAGC
CTAACTGAACTGCGTTGAGCTGCTTCAACTTTGGAATATATGTTTGCCAATCTCCTTGTTTTCTAATGAATAAATGTTTTTATATACTTT

>39747_39747_5_ING4-NCAPD2_ING4_chr12_6765892_ENST00000446105_NCAPD2_chr12_6618882_ENST00000315579_length(amino acids)=1400AA_BP=41
MFCFEMAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEAFQAAFRAQGPLAMLQHFDTIYSILHHFRSIDPGLKEDTLQFLIKVVSR
HSQELPAILDDTTLSGSDRNAHLNALKMNCYALIRLLESFETMASQTNLVDLDLGGKGKKARTKAAHGFDWEEERQPILQLLTQLLQLDI
RHLWNHSIIEEEFVSLVTGCCYRLLENPTINHQKNRPTREAITHLLGVALTRYNHMLSATVKIIQMLQHFEHLAPVLVAAVSLWATDYGM
KSIVGEIVREIGQKCPQELSRDPSGTKGFAAFLTELAERVPAILMSSMCILLDHLDGENYMMRNAVLAAMAEMVLQVLSGDQLEAAARDT
RDQFLDTLQAHGHDVNSFVRSRVLQLFTRIVQQKALPLTRFQAVVALAVGRLADKSVLVCKNAIQLLASFLANNPFSCKLSDADLAGPLQ
KETQKLQEMRAQRRTAAASAVLDPEEEWEAMLPELKSTLQQLLQLPQGEEEIPEQIANTETTEDVKGRIYQLLAKASYKKAIILTREATG
HFQESEPFSHIDPEESEETRLLNILGLIFKGPAASTQEKNPRESTGNMVTGQTVCKNKPNMSDPEESRGNDELVKQEMLVQYLQDAYSFS
RKITEAIGIISKMMYENTTTVVQEVIEFFVMVFQFGVPQALFGVRRMLPLIWSKEPGVREAVLNAYRQLYLNPKGDSARAKAQALIQNLS
LLLVDASVGTIQCLEEILCEFVQKDELKPAVTQLLWERATEKVACCPLERCSSVMLLGMMARGKPEIVGSNLDTLVSIGLDEKFPQDYRL
AQQVCHAIANISDRRKPSLGKRHPPFRLPQEHRLFERLRETVTKGFVHPDPLWIPFKEVAVTLIYQLAEGPEVICAQILQGCAKQALEKL
EEKRTSQEDPKESPAMLPTFLLMNLLSLAGDVALQQLVHLEQAVSGELCRRRVLREEQEHKTKDPKEKNTSSETTMEEELGLVGATADDT
EAELIRGICEMELLDGKQTLAAFVPLLLKVCNNPGLYSNPDLSAAASLALGKFCMISATFCDSQLRLLFTMLEKSPLPIVRSNLMVATGD
LAIRFPNLVDPWTPHLYARLRDPAQQVRKTAGLVMTHLILKDMVKVKGQVSEMAVLLIDPEPQIAALAKNFFNELSHKGNAIYNLLPDII
SRLSDPELGVEEEPFHTIMKQLLSYITKDKQTESLVEKLCQRFRTSRTERQQRDLAYCVSQLPLTERGLRKMLDNFDCFGDKLSDESIFS
AFLSVVGKLRRGAKPEGKAIIDEFEQKLRACHTRGLDGIKELEIGQAGSQRAPSAKKPSTGSRYQPLASTASDNDFVTPEPRRTTRRHPN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ING4-NCAPD2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ING4-NCAPD2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ING4-NCAPD2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource