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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:INPP4B-ARHGEF26 (FusionGDB2 ID:39781)

Fusion Gene Summary for INPP4B-ARHGEF26

check button Fusion gene summary
Fusion gene informationFusion gene name: INPP4B-ARHGEF26
Fusion gene ID: 39781
HgeneTgene
Gene symbol

INPP4B

ARHGEF26

Gene ID

8821

26084

Gene nameinositol polyphosphate-4-phosphatase type II BRho guanine nucleotide exchange factor 26
Synonyms-CSGEF|HMFN1864|SGEF
Cytomap

4q31.21

3q25.2

Type of geneprotein-codingprotein-coding
Descriptioninositol polyphosphate 4-phosphatase type IIinositol polyphosphate 4-phosphatase II; 4-phosphatase IIinositol polyphosphate-4-phosphatase, type II, 105kDatype II inositol 3,4-bisphosphate 4-phosphataserho guanine nucleotide exchange factor 26Rho guanine nucleotide exchange factor (GEF) 26SH3 domain-containing guanine exchange factorSrc homology 3 domain-containing guanine nucleotide exchange factortesticular tissue protein Li 171
Modification date2020031320200313
UniProtAcc.

Q96DR7

Ensembl transtripts involved in fusion geneENST00000262992, ENST00000308502, 
ENST00000506217, ENST00000508116, 
ENST00000509777, ENST00000513000, 
ENST00000507861, ENST00000508084, 
ENST00000465817, ENST00000483068, 
ENST00000356448, ENST00000465093, 
Fusion gene scores* DoF score13 X 12 X 5=7806 X 5 X 4=120
# samples 146
** MAII scorelog2(14/780*10)=-2.47804729680464
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: INPP4B [Title/Abstract] AND ARHGEF26 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointINPP4B(143324090)-ARHGEF26(153935657), # samples:1
Anticipated loss of major functional domain due to fusion event.INPP4B-ARHGEF26 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
INPP4B-ARHGEF26 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
INPP4B-ARHGEF26 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
INPP4B-ARHGEF26 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
INPP4B-ARHGEF26 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across INPP4B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ARHGEF26 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-C8-A12OINPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+


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Fusion Gene ORF analysis for INPP4B-ARHGEF26

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000262992ENST00000465817INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
5CDS-intronENST00000262992ENST00000483068INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
5CDS-intronENST00000308502ENST00000465817INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
5CDS-intronENST00000308502ENST00000483068INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
5CDS-intronENST00000506217ENST00000465817INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
5CDS-intronENST00000506217ENST00000483068INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
5CDS-intronENST00000508116ENST00000465817INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
5CDS-intronENST00000508116ENST00000483068INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
5CDS-intronENST00000509777ENST00000465817INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
5CDS-intronENST00000509777ENST00000483068INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
5CDS-intronENST00000513000ENST00000465817INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
5CDS-intronENST00000513000ENST00000483068INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
Frame-shiftENST00000262992ENST00000356448INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
Frame-shiftENST00000262992ENST00000465093INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
Frame-shiftENST00000508116ENST00000356448INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
Frame-shiftENST00000508116ENST00000465093INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
In-frameENST00000308502ENST00000356448INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
In-frameENST00000308502ENST00000465093INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
In-frameENST00000506217ENST00000356448INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
In-frameENST00000506217ENST00000465093INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
In-frameENST00000509777ENST00000356448INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
In-frameENST00000509777ENST00000465093INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
In-frameENST00000513000ENST00000356448INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
In-frameENST00000513000ENST00000465093INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
intron-3CDSENST00000507861ENST00000356448INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
intron-3CDSENST00000507861ENST00000465093INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
intron-3CDSENST00000508084ENST00000356448INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
intron-3CDSENST00000508084ENST00000465093INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
intron-intronENST00000507861ENST00000465817INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
intron-intronENST00000507861ENST00000483068INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
intron-intronENST00000508084ENST00000465817INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+
intron-intronENST00000508084ENST00000483068INPP4Bchr4

143324090

-ARHGEF26chr3

153935657

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000513000INPP4Bchr4143324090-ENST00000356448ARHGEF26chr3153935657+39318064281576382
ENST00000513000INPP4Bchr4143324090-ENST00000465093ARHGEF26chr3153935657+26798064281576382
ENST00000509777INPP4Bchr4143324090-ENST00000356448ARHGEF26chr3153935657+38427173391487382
ENST00000509777INPP4Bchr4143324090-ENST00000465093ARHGEF26chr3153935657+25907173391487382
ENST00000308502INPP4Bchr4143324090-ENST00000356448ARHGEF26chr3153935657+36174921141262382
ENST00000308502INPP4Bchr4143324090-ENST00000465093ARHGEF26chr3153935657+23654921141262382
ENST00000506217INPP4Bchr4143324090-ENST00000356448ARHGEF26chr3153935657+349737201142380
ENST00000506217INPP4Bchr4143324090-ENST00000465093ARHGEF26chr3153935657+224537201142380

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000513000ENST00000356448INPP4Bchr4143324090-ARHGEF26chr3153935657+0.0008083450.9991917
ENST00000513000ENST00000465093INPP4Bchr4143324090-ARHGEF26chr3153935657+0.0011913740.9988086
ENST00000509777ENST00000356448INPP4Bchr4143324090-ARHGEF26chr3153935657+0.000794870.9992052
ENST00000509777ENST00000465093INPP4Bchr4143324090-ARHGEF26chr3153935657+0.0011488730.99885106
ENST00000308502ENST00000356448INPP4Bchr4143324090-ARHGEF26chr3153935657+0.0006954760.99930453
ENST00000308502ENST00000465093INPP4Bchr4143324090-ARHGEF26chr3153935657+0.0009866650.9990133
ENST00000506217ENST00000356448INPP4Bchr4143324090-ARHGEF26chr3153935657+0.0006844290.9993156
ENST00000506217ENST00000465093INPP4Bchr4143324090-ARHGEF26chr3153935657+0.0009855190.9990145

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Fusion Genomic Features for INPP4B-ARHGEF26


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
INPP4Bchr4143324090-ARHGEF26chr3153935657+0.0006044090.9993956
INPP4Bchr4143324090-ARHGEF26chr3153935657+0.0006044090.9993956

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for INPP4B-ARHGEF26


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:143324090/chr3:153935657)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ARHGEF26

Q96DR7

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry. {ECO:0000269|PubMed:15133129, ECO:0000269|PubMed:17074883, ECO:0000269|PubMed:17875742}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneARHGEF26chr4:143324090chr3:153935657ENST0000046581705106_1730447.0Compositional biasNote=Pro-rich
TgeneARHGEF26chr4:143324090chr3:153935657ENST00000356448815655_782615872.0DomainPH
TgeneARHGEF26chr4:143324090chr3:153935657ENST00000356448815789_850615872.0DomainSH3
TgeneARHGEF26chr4:143324090chr3:153935657ENST00000465093815655_782615872.0DomainPH
TgeneARHGEF26chr4:143324090chr3:153935657ENST00000465093815789_850615872.0DomainSH3
TgeneARHGEF26chr4:143324090chr3:153935657ENST0000046581705439_6230447.0DomainDH
TgeneARHGEF26chr4:143324090chr3:153935657ENST0000046581705655_7820447.0DomainPH
TgeneARHGEF26chr4:143324090chr3:153935657ENST0000046581705789_8500447.0DomainSH3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneINPP4Bchr4:143324090chr3:153935657ENST00000262992-52423_165124925.0DomainC2
HgeneINPP4Bchr4:143324090chr3:153935657ENST00000308502-42323_165124925.0DomainC2
HgeneINPP4Bchr4:143324090chr3:153935657ENST00000506217-4523_165124132.0DomainC2
HgeneINPP4Bchr4:143324090chr3:153935657ENST00000508116-62523_165124925.0DomainC2
HgeneINPP4Bchr4:143324090chr3:153935657ENST00000513000-82723_165124925.0DomainC2
TgeneARHGEF26chr4:143324090chr3:153935657ENST00000356448815106_173615872.0Compositional biasNote=Pro-rich
TgeneARHGEF26chr4:143324090chr3:153935657ENST00000465093815106_173615872.0Compositional biasNote=Pro-rich
TgeneARHGEF26chr4:143324090chr3:153935657ENST00000356448815439_623615872.0DomainDH
TgeneARHGEF26chr4:143324090chr3:153935657ENST00000465093815439_623615872.0DomainDH


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Fusion Gene Sequence for INPP4B-ARHGEF26


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>39781_39781_1_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000308502_ARHGEF26_chr3_153935657_ENST00000356448_length(transcript)=3617nt_BP=492nt
AATTTCAGAGTGGGATATCAGATCTTTAGTGTGAAGATACATCTACATTAAACCAGGAATCACTAGAACTGACATTTGGACAAGAAAATT
TGGAAAATTTTAAAACTGTGAAGGTTGATCATGGAAATTAAAGAGGAAGGGGCATCAGAAGAAGGGCAGCACTTTCTTCCTACAGCCCAG
GCCAATGATCCCGGGGACTGTCAGTTCACAAGTATCCAGAAGACTCCAAATGAACCGCAGTTGGAATTCATCCTTGCATGCAAGGATCTC
GTGGCTCCTGTCCGTGATCGTAAACTGAATACACTGGTGCAGATCTCCGTAATCCACCCCGTGGAGCAGAGTCTGACAAGATACTCCAGC
ACCGAAATTGTGGAGGGAACAAGGGACCCACTGTTTTTGACTGGTGTCACATTCCCATCTGAGTATCCCATCTATGAGGAGACCAAAATA
AAACTAACAGTCTATGATGTCAAGGATAAGTCTCATGACACCTTGGTTCGACTATGCAATGAGGGCGCCCGGAAGATGGAAAGGACTGAG
ATGATGTACACAATTAACTCCCAGCTGGAATTTAAAATTAAGCCTTTTCCTTTAGTCTCCTCTTCCCGGTGGTTGGTAAAAAGAGGTGAA
TTGACAGCCTATGTTGAAGACACTGTGCTTTTCTCAAGAAGGACATCCAAACAGCAAGTCTACTTCTTTCTCTTTAACGATGTGCTCATT
ATCACCAAGAAGAAGAGTGAAGAAAGTTACAACGTCAATGATTATTCCTTAAGAGATCAGCTATTGGTGGAATCTTGTGACAATGAAGAG
CTTAATTCTTCTCCAGGGAAGAACAGCTCCACAATGCTCTATTCAAGACAGAGCTCTGCCAGTCACCTCTTTACTCTGACAGTCCTTAGT
AACCACGCGAATGAGAAAGTGGAGATGCTACTAGGAGCTGAGACGCAGAGCGAGCGAGCCCGCTGGATAACTGCCCTGGGACACAGCAGC
GGGAAGCCGCCTGCAGACCGAACCTCACTGACCCAGGTGGAAATCGTTAGGTCATTTACTGCTAAGCAGCCAGATGAACTCTCCCTGCAG
GTGGCTGACGTCGTCCTCATCTATCAACGTGTCAGCGATGGCTGGTATGAGGGGGAACGACTACGAGATGGAGAAAGAGGCTGGTTTCCT
ATGGAATGTGCCAAGGAGATAACATGTCAAGCTACAATTGATAAGAATGTGGAGAGAATGGGACGCTTGCTAGGACTGGAGACCAACGTG
TAGTCTCTCAGATGGTCTTTTGTTACTGCAAGATTTGCACGACACTTACCGGGCTGGTTGGTTCTGGGCTAGTTTTATTGTTAATTTTGT
CACAGCCTATTTAATTAAAAGAACGAAAACACTTGCCTTTAAGCTTGCCAGGTTGTTCTGCTCTCTCATGAGAAGAGCTTGGATACAGTG
AGTTTGCACAGCTCAGTTTTTACCTAACCACACACTTGCAGACCTCCTGAGGTACACAGAATAGCTGAGCAGTTCACTTCAGGGATCAGG
TCATCTCTGCTCCTCCTAGTTTCACCATGTTCTGGCAATAAAAAACACATATTATATCCTGGTTTTCTCTATCCTTGCATTACTAAGGTG
ACTGTCTCTCTTTATACATCCTTGTATGGTTCTCCCAGTATTAGCAAGATTGTATATCTGTAAAGAATGTCCAGTTTTGTAAATATTTCC
CTGCCTTTTTTTTTCTTTTTTTACATCTGATTTTAATGCTTCGTTAACTTCAAAAGGAACTGGTAGAGTTCAGAAGGTGAGCTGTTGTTT
TTCTAAACCTCTTCCCAGGAAGGGGACATTGACACTTGAATTTTTGTCACCTTTTTCCTCATTAGAAGGAAAGTAGAAAGCCTTACTTTA
GGATTTTTAAAAAAAAATCCATCTCACCCCATATTGTTCTTAAATAAGTATAGACTAATTAACCTAAGCTACCTTTAACAACGTAGAATT
TAGATGGGTTCATATATGTGAGAAAAACCTGAATATAGGACAGGGGTCCTACTTTTTTCCCCACCTCTGTCGCCCAGGCTAGAGTATAGT
GGTGTGATCTTGGCCCACTGCAACCTCTGCTTCCTAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTGTAAGAGTA
TGCCACCACGCCCAGCTACTTTTTGTATTTTTAGTAGAGACAGGGTTTCATCATGTTGGCCAGGATGGTCTCTTAACTCCTGCCCTCAAG
TGATCCACCAGAGAGGAGATCCTCGGCCTCCCCAAGTGCTGGGATTATAGGCATGAGCCACCGTGCCCAGCCTACTTTCTAATTAATTAA
AAAAAAAAAAAAAAAAAAAAAAAAACCTTCCCAAATGAGCTGATAAAAAACTGACGTGAGGCTGCTTTGCCTTCAATAATACCTAGTTTT
CAGCTGTTCCAACTCGTTTCCAAATAGAAATTAGCTGGAACACACTACAGTAATCTCAAGGAAGGGAAAATTAGGCCTTAAAAGATACCA
AGAAGTCAGCATGGTACCCAATTGAAACCTTTTGACCTTAGTGGGAATTCATTCTATTTGCACTAAAAGCCTTAACTTGCTGTATTCAGA
GTCCCTCTTAACTGTGAGTTTCTATAGAACTTTACTTTTTCCACTAGTGCACAGAGAGAGAAAGGTTATCTTAATAGTCGGTTTCATGGA
GATGAAGGATGGGAGATTAAGAGGGGGGAAATGATTTTTACTGGCAGCTATATTCCCTCTCTGTTCTATTTGCTTTAACAAAGGGATAAA
ACCTGGCAAAGTGTACATTATTGGAGGACTCAAATCTGTATGTGACATGTCCCAACTACTGTCCGCTAACTAGTTATCCAAATTGTAAAG
CTACAGAAGCCCAGTTGAGGGGTAAGTGTGCCTGGCTCACACAGCCTGCACCCTGTCACCTCGGCAATGAGCCAGTGTGGGGCACTGGGG
ACTTCTAACCCTTGGATTGCTCTTTTTGACCTGTGCATACCTTCTAATTGTAAAATATATTTCAGACCGTGAGTACCTTGAGATCTGAGC
AACTGTGTTAATGAAGTAATAGCAATGGTCCACAGTGAAAGATGTGTTGGGGTTTGCAAAACAAGCATTCCGTCACCTCTTTAATAATGT
CACAGACTTTTTAAAAGAGAGGCTATCAAGTTGTAATATAATCTGTCATGTTTTATTTAGGAAGGAAGGTAAATTTGTGCTTGCACGGGG
ATCATTTTGTATTATTTTTGCTAATACCCAGTTGAAGCTAAAAAGCAACTATTTGAATCCTGTGAATTAATTTATAAGAATGTTAAACAG
CTTTGGAAATACATGCATCTTATGAATCATAGCCTTATTTAGCAAGATCAATGTTAAAGTGTTGTTATATGGCAAGTATTTAACACATTC
ACAGTGTTTGTTTGATTTCAACTGTGAATTGTCTTAAGTTTTTTCAAACCTAGTTGTTTCTATGGACACCTGCTCTGAATTGTACATTGA
CTTCATTACTAAAGAACAAAAATGTTCATTTTTGTCCCAGTAAATTGAGACTGCTTGTACACTTTCAGAAAAATATGTGAATTTATAAAG

>39781_39781_1_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000308502_ARHGEF26_chr3_153935657_ENST00000356448_length(amino acids)=382AA_BP=126
MIMEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTR
DPLFLTGVTFPSEYPIYEETKIKLTVYDVKDKSHDTLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDT
VLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVE
MLLGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEIT

--------------------------------------------------------------
>39781_39781_2_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000308502_ARHGEF26_chr3_153935657_ENST00000465093_length(transcript)=2365nt_BP=492nt
AATTTCAGAGTGGGATATCAGATCTTTAGTGTGAAGATACATCTACATTAAACCAGGAATCACTAGAACTGACATTTGGACAAGAAAATT
TGGAAAATTTTAAAACTGTGAAGGTTGATCATGGAAATTAAAGAGGAAGGGGCATCAGAAGAAGGGCAGCACTTTCTTCCTACAGCCCAG
GCCAATGATCCCGGGGACTGTCAGTTCACAAGTATCCAGAAGACTCCAAATGAACCGCAGTTGGAATTCATCCTTGCATGCAAGGATCTC
GTGGCTCCTGTCCGTGATCGTAAACTGAATACACTGGTGCAGATCTCCGTAATCCACCCCGTGGAGCAGAGTCTGACAAGATACTCCAGC
ACCGAAATTGTGGAGGGAACAAGGGACCCACTGTTTTTGACTGGTGTCACATTCCCATCTGAGTATCCCATCTATGAGGAGACCAAAATA
AAACTAACAGTCTATGATGTCAAGGATAAGTCTCATGACACCTTGGTTCGACTATGCAATGAGGGCGCCCGGAAGATGGAAAGGACTGAG
ATGATGTACACAATTAACTCCCAGCTGGAATTTAAAATTAAGCCTTTTCCTTTAGTCTCCTCTTCCCGGTGGTTGGTAAAAAGAGGTGAA
TTGACAGCCTATGTTGAAGACACTGTGCTTTTCTCAAGAAGGACATCCAAACAGCAAGTCTACTTCTTTCTCTTTAACGATGTGCTCATT
ATCACCAAGAAGAAGAGTGAAGAAAGTTACAACGTCAATGATTATTCCTTAAGAGATCAGCTATTGGTGGAATCTTGTGACAATGAAGAG
CTTAATTCTTCTCCAGGGAAGAACAGCTCCACAATGCTCTATTCAAGACAGAGCTCTGCCAGTCACCTCTTTACTCTGACAGTCCTTAGT
AACCACGCGAATGAGAAAGTGGAGATGCTACTAGGAGCTGAGACGCAGAGCGAGCGAGCCCGCTGGATAACTGCCCTGGGACACAGCAGC
GGGAAGCCGCCTGCAGACCGAACCTCACTGACCCAGGTGGAAATCGTTAGGTCATTTACTGCTAAGCAGCCAGATGAACTCTCCCTGCAG
GTGGCTGACGTCGTCCTCATCTATCAACGTGTCAGCGATGGCTGGTATGAGGGGGAACGACTACGAGATGGAGAAAGAGGCTGGTTTCCT
ATGGAATGTGCCAAGGAGATAACATGTCAAGCTACAATTGATAAGAATGTGGAGAGAATGGGACGCTTGCTAGGACTGGAGACCAACGTG
TAGTCTCTCAGATGGTCTTTTGTTACTGCAAGATTTGCACGACACTTACCGGGCTGGTTGGTTCTGGGCTAGTTTTATTGTTAATTTTGT
CACAGCCTATTTAATTAAAAGAACGAAAACACTTGCCTTTAAGCTTGCCAGGTTGTTCTGCTCTCTCATGAGAAGAGCTTGGATACAGTG
AGTTTGCACAGCTCAGTTTTTACCTAACCACACACTTGCAGACCTCCTGAGGTACACAGAATAGCTGAGCAGTTCACTTCAGGGATCAGG
TCATCTCTGCTCCTCCTAGTTTCACCATGTTCTGGCAATAAAAAACACATATTATATCCTGGTTTTCTCTATCCTTGCATTACTAAGGTG
ACTGTCTCTCTTTATACATCCTTGTATGGTTCTCCCAGTATTAGCAAGATTGTATATCTGTAAAGAATGTCCAGTTTTGTAAATATTTCC
CTGCCTTTTTTTTTCTTTTTTTACATCTGATTTTAATGCTTCGTTAACTTCAAAAGGAACTGGTAGAGTTCAGAAGGTGAGCTGTTGTTT
TTCTAAACCTCTTCCCAGGAAGGGGACATTGACACTTGAATTTTTGTCACCTTTTTCCTCATTAGAAGGAAAGTAGAAAGCCTTACTTTA
GGATTTTTAAAAAAAAATCCATCTCACCCCATATTGTTCTTAAATAAGTATAGACTAATTAACCTAAGCTACCTTTAACAACGTAGAATT
TAGATGGGTTCATATATGTGAGAAAAACCTGAATATAGGACAGGGGTCCTACTTTTTTCCCCACCTCTGTCGCCCAGGCTAGAGTATAGT
GGTGTGATCTTGGCCCACTGCAACCTCTGCTTCCTAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTGTAAGAGTA
TGCCACCACGCCCAGCTACTTTTTGTATTTTTAGTAGAGACAGGGTTTCATCATGTTGGCCAGGATGGTCTCTTAACTCCTGCCCTCAAG
TGATCCACCAGAGAGGAGATCCTCGGCCTCCCCAAGTGCTGGGATTATAGGCATGAGCCACCGTGCCCAGCCTACTTTCTAATTAATTAA

>39781_39781_2_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000308502_ARHGEF26_chr3_153935657_ENST00000465093_length(amino acids)=382AA_BP=126
MIMEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTR
DPLFLTGVTFPSEYPIYEETKIKLTVYDVKDKSHDTLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDT
VLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVE
MLLGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEIT

--------------------------------------------------------------
>39781_39781_3_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000506217_ARHGEF26_chr3_153935657_ENST00000356448_length(transcript)=3497nt_BP=372nt
ATGGAAATTAAAGAGGAAGGGGCATCAGAAGAAGGGCAGCACTTTCTTCCTACAGCCCAGGCCAATGATCCCGGGGACTGTCAGTTCACA
AGTATCCAGAAGACTCCAAATGAACCGCAGTTGGAATTCATCCTTGCATGCAAGGATCTCGTGGCTCCTGTCCGTGATCGTAAACTGAAT
ACACTGGTGCAGATCTCCGTAATCCACCCCGTGGAGCAGAGTCTGACAAGATACTCCAGCACCGAAATTGTGGAGGGAACAAGGGACCCA
CTGTTTTTGACTGGTGTCACATTCCCATCTGAGTATCCCATCTATGAGGAGACCAAAATAAAACTAACAGTCTATGATGTCAAGGATAAG
TCTCATGACACCTTGGTTCGACTATGCAATGAGGGCGCCCGGAAGATGGAAAGGACTGAGATGATGTACACAATTAACTCCCAGCTGGAA
TTTAAAATTAAGCCTTTTCCTTTAGTCTCCTCTTCCCGGTGGTTGGTAAAAAGAGGTGAATTGACAGCCTATGTTGAAGACACTGTGCTT
TTCTCAAGAAGGACATCCAAACAGCAAGTCTACTTCTTTCTCTTTAACGATGTGCTCATTATCACCAAGAAGAAGAGTGAAGAAAGTTAC
AACGTCAATGATTATTCCTTAAGAGATCAGCTATTGGTGGAATCTTGTGACAATGAAGAGCTTAATTCTTCTCCAGGGAAGAACAGCTCC
ACAATGCTCTATTCAAGACAGAGCTCTGCCAGTCACCTCTTTACTCTGACAGTCCTTAGTAACCACGCGAATGAGAAAGTGGAGATGCTA
CTAGGAGCTGAGACGCAGAGCGAGCGAGCCCGCTGGATAACTGCCCTGGGACACAGCAGCGGGAAGCCGCCTGCAGACCGAACCTCACTG
ACCCAGGTGGAAATCGTTAGGTCATTTACTGCTAAGCAGCCAGATGAACTCTCCCTGCAGGTGGCTGACGTCGTCCTCATCTATCAACGT
GTCAGCGATGGCTGGTATGAGGGGGAACGACTACGAGATGGAGAAAGAGGCTGGTTTCCTATGGAATGTGCCAAGGAGATAACATGTCAA
GCTACAATTGATAAGAATGTGGAGAGAATGGGACGCTTGCTAGGACTGGAGACCAACGTGTAGTCTCTCAGATGGTCTTTTGTTACTGCA
AGATTTGCACGACACTTACCGGGCTGGTTGGTTCTGGGCTAGTTTTATTGTTAATTTTGTCACAGCCTATTTAATTAAAAGAACGAAAAC
ACTTGCCTTTAAGCTTGCCAGGTTGTTCTGCTCTCTCATGAGAAGAGCTTGGATACAGTGAGTTTGCACAGCTCAGTTTTTACCTAACCA
CACACTTGCAGACCTCCTGAGGTACACAGAATAGCTGAGCAGTTCACTTCAGGGATCAGGTCATCTCTGCTCCTCCTAGTTTCACCATGT
TCTGGCAATAAAAAACACATATTATATCCTGGTTTTCTCTATCCTTGCATTACTAAGGTGACTGTCTCTCTTTATACATCCTTGTATGGT
TCTCCCAGTATTAGCAAGATTGTATATCTGTAAAGAATGTCCAGTTTTGTAAATATTTCCCTGCCTTTTTTTTTCTTTTTTTACATCTGA
TTTTAATGCTTCGTTAACTTCAAAAGGAACTGGTAGAGTTCAGAAGGTGAGCTGTTGTTTTTCTAAACCTCTTCCCAGGAAGGGGACATT
GACACTTGAATTTTTGTCACCTTTTTCCTCATTAGAAGGAAAGTAGAAAGCCTTACTTTAGGATTTTTAAAAAAAAATCCATCTCACCCC
ATATTGTTCTTAAATAAGTATAGACTAATTAACCTAAGCTACCTTTAACAACGTAGAATTTAGATGGGTTCATATATGTGAGAAAAACCT
GAATATAGGACAGGGGTCCTACTTTTTTCCCCACCTCTGTCGCCCAGGCTAGAGTATAGTGGTGTGATCTTGGCCCACTGCAACCTCTGC
TTCCTAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTGTAAGAGTATGCCACCACGCCCAGCTACTTTTTGTATTT
TTAGTAGAGACAGGGTTTCATCATGTTGGCCAGGATGGTCTCTTAACTCCTGCCCTCAAGTGATCCACCAGAGAGGAGATCCTCGGCCTC
CCCAAGTGCTGGGATTATAGGCATGAGCCACCGTGCCCAGCCTACTTTCTAATTAATTAAAAAAAAAAAAAAAAAAAAAAAAAAACCTTC
CCAAATGAGCTGATAAAAAACTGACGTGAGGCTGCTTTGCCTTCAATAATACCTAGTTTTCAGCTGTTCCAACTCGTTTCCAAATAGAAA
TTAGCTGGAACACACTACAGTAATCTCAAGGAAGGGAAAATTAGGCCTTAAAAGATACCAAGAAGTCAGCATGGTACCCAATTGAAACCT
TTTGACCTTAGTGGGAATTCATTCTATTTGCACTAAAAGCCTTAACTTGCTGTATTCAGAGTCCCTCTTAACTGTGAGTTTCTATAGAAC
TTTACTTTTTCCACTAGTGCACAGAGAGAGAAAGGTTATCTTAATAGTCGGTTTCATGGAGATGAAGGATGGGAGATTAAGAGGGGGGAA
ATGATTTTTACTGGCAGCTATATTCCCTCTCTGTTCTATTTGCTTTAACAAAGGGATAAAACCTGGCAAAGTGTACATTATTGGAGGACT
CAAATCTGTATGTGACATGTCCCAACTACTGTCCGCTAACTAGTTATCCAAATTGTAAAGCTACAGAAGCCCAGTTGAGGGGTAAGTGTG
CCTGGCTCACACAGCCTGCACCCTGTCACCTCGGCAATGAGCCAGTGTGGGGCACTGGGGACTTCTAACCCTTGGATTGCTCTTTTTGAC
CTGTGCATACCTTCTAATTGTAAAATATATTTCAGACCGTGAGTACCTTGAGATCTGAGCAACTGTGTTAATGAAGTAATAGCAATGGTC
CACAGTGAAAGATGTGTTGGGGTTTGCAAAACAAGCATTCCGTCACCTCTTTAATAATGTCACAGACTTTTTAAAAGAGAGGCTATCAAG
TTGTAATATAATCTGTCATGTTTTATTTAGGAAGGAAGGTAAATTTGTGCTTGCACGGGGATCATTTTGTATTATTTTTGCTAATACCCA
GTTGAAGCTAAAAAGCAACTATTTGAATCCTGTGAATTAATTTATAAGAATGTTAAACAGCTTTGGAAATACATGCATCTTATGAATCAT
AGCCTTATTTAGCAAGATCAATGTTAAAGTGTTGTTATATGGCAAGTATTTAACACATTCACAGTGTTTGTTTGATTTCAACTGTGAATT
GTCTTAAGTTTTTTCAAACCTAGTTGTTTCTATGGACACCTGCTCTGAATTGTACATTGACTTCATTACTAAAGAACAAAAATGTTCATT

>39781_39781_3_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000506217_ARHGEF26_chr3_153935657_ENST00000356448_length(amino acids)=380AA_BP=124
MEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDP
LFLTGVTFPSEYPIYEETKIKLTVYDVKDKSHDTLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVL
FSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEML
LGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEITCQ

--------------------------------------------------------------
>39781_39781_4_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000506217_ARHGEF26_chr3_153935657_ENST00000465093_length(transcript)=2245nt_BP=372nt
ATGGAAATTAAAGAGGAAGGGGCATCAGAAGAAGGGCAGCACTTTCTTCCTACAGCCCAGGCCAATGATCCCGGGGACTGTCAGTTCACA
AGTATCCAGAAGACTCCAAATGAACCGCAGTTGGAATTCATCCTTGCATGCAAGGATCTCGTGGCTCCTGTCCGTGATCGTAAACTGAAT
ACACTGGTGCAGATCTCCGTAATCCACCCCGTGGAGCAGAGTCTGACAAGATACTCCAGCACCGAAATTGTGGAGGGAACAAGGGACCCA
CTGTTTTTGACTGGTGTCACATTCCCATCTGAGTATCCCATCTATGAGGAGACCAAAATAAAACTAACAGTCTATGATGTCAAGGATAAG
TCTCATGACACCTTGGTTCGACTATGCAATGAGGGCGCCCGGAAGATGGAAAGGACTGAGATGATGTACACAATTAACTCCCAGCTGGAA
TTTAAAATTAAGCCTTTTCCTTTAGTCTCCTCTTCCCGGTGGTTGGTAAAAAGAGGTGAATTGACAGCCTATGTTGAAGACACTGTGCTT
TTCTCAAGAAGGACATCCAAACAGCAAGTCTACTTCTTTCTCTTTAACGATGTGCTCATTATCACCAAGAAGAAGAGTGAAGAAAGTTAC
AACGTCAATGATTATTCCTTAAGAGATCAGCTATTGGTGGAATCTTGTGACAATGAAGAGCTTAATTCTTCTCCAGGGAAGAACAGCTCC
ACAATGCTCTATTCAAGACAGAGCTCTGCCAGTCACCTCTTTACTCTGACAGTCCTTAGTAACCACGCGAATGAGAAAGTGGAGATGCTA
CTAGGAGCTGAGACGCAGAGCGAGCGAGCCCGCTGGATAACTGCCCTGGGACACAGCAGCGGGAAGCCGCCTGCAGACCGAACCTCACTG
ACCCAGGTGGAAATCGTTAGGTCATTTACTGCTAAGCAGCCAGATGAACTCTCCCTGCAGGTGGCTGACGTCGTCCTCATCTATCAACGT
GTCAGCGATGGCTGGTATGAGGGGGAACGACTACGAGATGGAGAAAGAGGCTGGTTTCCTATGGAATGTGCCAAGGAGATAACATGTCAA
GCTACAATTGATAAGAATGTGGAGAGAATGGGACGCTTGCTAGGACTGGAGACCAACGTGTAGTCTCTCAGATGGTCTTTTGTTACTGCA
AGATTTGCACGACACTTACCGGGCTGGTTGGTTCTGGGCTAGTTTTATTGTTAATTTTGTCACAGCCTATTTAATTAAAAGAACGAAAAC
ACTTGCCTTTAAGCTTGCCAGGTTGTTCTGCTCTCTCATGAGAAGAGCTTGGATACAGTGAGTTTGCACAGCTCAGTTTTTACCTAACCA
CACACTTGCAGACCTCCTGAGGTACACAGAATAGCTGAGCAGTTCACTTCAGGGATCAGGTCATCTCTGCTCCTCCTAGTTTCACCATGT
TCTGGCAATAAAAAACACATATTATATCCTGGTTTTCTCTATCCTTGCATTACTAAGGTGACTGTCTCTCTTTATACATCCTTGTATGGT
TCTCCCAGTATTAGCAAGATTGTATATCTGTAAAGAATGTCCAGTTTTGTAAATATTTCCCTGCCTTTTTTTTTCTTTTTTTACATCTGA
TTTTAATGCTTCGTTAACTTCAAAAGGAACTGGTAGAGTTCAGAAGGTGAGCTGTTGTTTTTCTAAACCTCTTCCCAGGAAGGGGACATT
GACACTTGAATTTTTGTCACCTTTTTCCTCATTAGAAGGAAAGTAGAAAGCCTTACTTTAGGATTTTTAAAAAAAAATCCATCTCACCCC
ATATTGTTCTTAAATAAGTATAGACTAATTAACCTAAGCTACCTTTAACAACGTAGAATTTAGATGGGTTCATATATGTGAGAAAAACCT
GAATATAGGACAGGGGTCCTACTTTTTTCCCCACCTCTGTCGCCCAGGCTAGAGTATAGTGGTGTGATCTTGGCCCACTGCAACCTCTGC
TTCCTAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTGTAAGAGTATGCCACCACGCCCAGCTACTTTTTGTATTT
TTAGTAGAGACAGGGTTTCATCATGTTGGCCAGGATGGTCTCTTAACTCCTGCCCTCAAGTGATCCACCAGAGAGGAGATCCTCGGCCTC

>39781_39781_4_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000506217_ARHGEF26_chr3_153935657_ENST00000465093_length(amino acids)=380AA_BP=124
MEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDP
LFLTGVTFPSEYPIYEETKIKLTVYDVKDKSHDTLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVL
FSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEML
LGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEITCQ

--------------------------------------------------------------
>39781_39781_5_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000509777_ARHGEF26_chr3_153935657_ENST00000356448_length(transcript)=3842nt_BP=717nt
CGCACACGCTCACACGCTCGCAAGCGAACGCAGGAAAGTCAGGCTAAAAGTGTCTGCTGCTGCTGCCGCCCCCCACTCCGCCTCCGGGAG
AGAATACAAAGAAATGGTGTTACCTGGCAAGAGGTCTTCTGTCTTTTATGAAAAATTAGACAAAGAGCCTTGAAACCAGCGAAACAATAA
TCAAAGAGCAGTTCTGTCAAAGAAAACAACATAAATCAGGTACAGAATTTCAGAGTGGGATATCAGATCTTTAGTGTGAAGATACATCTA
CATTAAACCAGGAATCACTAGAACTGACATTTGGACAAGAAAATTTGGAAAATTTTAAAACTGTGAAGGTTGATCATGGAAATTAAAGAG
GAAGGGGCATCAGAAGAAGGGCAGCACTTTCTTCCTACAGCCCAGGCCAATGATCCCGGGGACTGTCAGTTCACAAGTATCCAGAAGACT
CCAAATGAACCGCAGTTGGAATTCATCCTTGCATGCAAGGATCTCGTGGCTCCTGTCCGTGATCGTAAACTGAATACACTGGTGCAGATC
TCCGTAATCCACCCCGTGGAGCAGAGTCTGACAAGATACTCCAGCACCGAAATTGTGGAGGGAACAAGGGACCCACTGTTTTTGACTGGT
GTCACATTCCCATCTGAGTATCCCATCTATGAGGAGACCAAAATAAAACTAACAGTCTATGATGTCAAGGATAAGTCTCATGACACCTTG
GTTCGACTATGCAATGAGGGCGCCCGGAAGATGGAAAGGACTGAGATGATGTACACAATTAACTCCCAGCTGGAATTTAAAATTAAGCCT
TTTCCTTTAGTCTCCTCTTCCCGGTGGTTGGTAAAAAGAGGTGAATTGACAGCCTATGTTGAAGACACTGTGCTTTTCTCAAGAAGGACA
TCCAAACAGCAAGTCTACTTCTTTCTCTTTAACGATGTGCTCATTATCACCAAGAAGAAGAGTGAAGAAAGTTACAACGTCAATGATTAT
TCCTTAAGAGATCAGCTATTGGTGGAATCTTGTGACAATGAAGAGCTTAATTCTTCTCCAGGGAAGAACAGCTCCACAATGCTCTATTCA
AGACAGAGCTCTGCCAGTCACCTCTTTACTCTGACAGTCCTTAGTAACCACGCGAATGAGAAAGTGGAGATGCTACTAGGAGCTGAGACG
CAGAGCGAGCGAGCCCGCTGGATAACTGCCCTGGGACACAGCAGCGGGAAGCCGCCTGCAGACCGAACCTCACTGACCCAGGTGGAAATC
GTTAGGTCATTTACTGCTAAGCAGCCAGATGAACTCTCCCTGCAGGTGGCTGACGTCGTCCTCATCTATCAACGTGTCAGCGATGGCTGG
TATGAGGGGGAACGACTACGAGATGGAGAAAGAGGCTGGTTTCCTATGGAATGTGCCAAGGAGATAACATGTCAAGCTACAATTGATAAG
AATGTGGAGAGAATGGGACGCTTGCTAGGACTGGAGACCAACGTGTAGTCTCTCAGATGGTCTTTTGTTACTGCAAGATTTGCACGACAC
TTACCGGGCTGGTTGGTTCTGGGCTAGTTTTATTGTTAATTTTGTCACAGCCTATTTAATTAAAAGAACGAAAACACTTGCCTTTAAGCT
TGCCAGGTTGTTCTGCTCTCTCATGAGAAGAGCTTGGATACAGTGAGTTTGCACAGCTCAGTTTTTACCTAACCACACACTTGCAGACCT
CCTGAGGTACACAGAATAGCTGAGCAGTTCACTTCAGGGATCAGGTCATCTCTGCTCCTCCTAGTTTCACCATGTTCTGGCAATAAAAAA
CACATATTATATCCTGGTTTTCTCTATCCTTGCATTACTAAGGTGACTGTCTCTCTTTATACATCCTTGTATGGTTCTCCCAGTATTAGC
AAGATTGTATATCTGTAAAGAATGTCCAGTTTTGTAAATATTTCCCTGCCTTTTTTTTTCTTTTTTTACATCTGATTTTAATGCTTCGTT
AACTTCAAAAGGAACTGGTAGAGTTCAGAAGGTGAGCTGTTGTTTTTCTAAACCTCTTCCCAGGAAGGGGACATTGACACTTGAATTTTT
GTCACCTTTTTCCTCATTAGAAGGAAAGTAGAAAGCCTTACTTTAGGATTTTTAAAAAAAAATCCATCTCACCCCATATTGTTCTTAAAT
AAGTATAGACTAATTAACCTAAGCTACCTTTAACAACGTAGAATTTAGATGGGTTCATATATGTGAGAAAAACCTGAATATAGGACAGGG
GTCCTACTTTTTTCCCCACCTCTGTCGCCCAGGCTAGAGTATAGTGGTGTGATCTTGGCCCACTGCAACCTCTGCTTCCTAGGTTCAAGT
GATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTGTAAGAGTATGCCACCACGCCCAGCTACTTTTTGTATTTTTAGTAGAGACAGGG
TTTCATCATGTTGGCCAGGATGGTCTCTTAACTCCTGCCCTCAAGTGATCCACCAGAGAGGAGATCCTCGGCCTCCCCAAGTGCTGGGAT
TATAGGCATGAGCCACCGTGCCCAGCCTACTTTCTAATTAATTAAAAAAAAAAAAAAAAAAAAAAAAAAACCTTCCCAAATGAGCTGATA
AAAAACTGACGTGAGGCTGCTTTGCCTTCAATAATACCTAGTTTTCAGCTGTTCCAACTCGTTTCCAAATAGAAATTAGCTGGAACACAC
TACAGTAATCTCAAGGAAGGGAAAATTAGGCCTTAAAAGATACCAAGAAGTCAGCATGGTACCCAATTGAAACCTTTTGACCTTAGTGGG
AATTCATTCTATTTGCACTAAAAGCCTTAACTTGCTGTATTCAGAGTCCCTCTTAACTGTGAGTTTCTATAGAACTTTACTTTTTCCACT
AGTGCACAGAGAGAGAAAGGTTATCTTAATAGTCGGTTTCATGGAGATGAAGGATGGGAGATTAAGAGGGGGGAAATGATTTTTACTGGC
AGCTATATTCCCTCTCTGTTCTATTTGCTTTAACAAAGGGATAAAACCTGGCAAAGTGTACATTATTGGAGGACTCAAATCTGTATGTGA
CATGTCCCAACTACTGTCCGCTAACTAGTTATCCAAATTGTAAAGCTACAGAAGCCCAGTTGAGGGGTAAGTGTGCCTGGCTCACACAGC
CTGCACCCTGTCACCTCGGCAATGAGCCAGTGTGGGGCACTGGGGACTTCTAACCCTTGGATTGCTCTTTTTGACCTGTGCATACCTTCT
AATTGTAAAATATATTTCAGACCGTGAGTACCTTGAGATCTGAGCAACTGTGTTAATGAAGTAATAGCAATGGTCCACAGTGAAAGATGT
GTTGGGGTTTGCAAAACAAGCATTCCGTCACCTCTTTAATAATGTCACAGACTTTTTAAAAGAGAGGCTATCAAGTTGTAATATAATCTG
TCATGTTTTATTTAGGAAGGAAGGTAAATTTGTGCTTGCACGGGGATCATTTTGTATTATTTTTGCTAATACCCAGTTGAAGCTAAAAAG
CAACTATTTGAATCCTGTGAATTAATTTATAAGAATGTTAAACAGCTTTGGAAATACATGCATCTTATGAATCATAGCCTTATTTAGCAA
GATCAATGTTAAAGTGTTGTTATATGGCAAGTATTTAACACATTCACAGTGTTTGTTTGATTTCAACTGTGAATTGTCTTAAGTTTTTTC
AAACCTAGTTGTTTCTATGGACACCTGCTCTGAATTGTACATTGACTTCATTACTAAAGAACAAAAATGTTCATTTTTGTCCCAGTAAAT

>39781_39781_5_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000509777_ARHGEF26_chr3_153935657_ENST00000356448_length(amino acids)=382AA_BP=126
MIMEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTR
DPLFLTGVTFPSEYPIYEETKIKLTVYDVKDKSHDTLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDT
VLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVE
MLLGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEIT

--------------------------------------------------------------
>39781_39781_6_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000509777_ARHGEF26_chr3_153935657_ENST00000465093_length(transcript)=2590nt_BP=717nt
CGCACACGCTCACACGCTCGCAAGCGAACGCAGGAAAGTCAGGCTAAAAGTGTCTGCTGCTGCTGCCGCCCCCCACTCCGCCTCCGGGAG
AGAATACAAAGAAATGGTGTTACCTGGCAAGAGGTCTTCTGTCTTTTATGAAAAATTAGACAAAGAGCCTTGAAACCAGCGAAACAATAA
TCAAAGAGCAGTTCTGTCAAAGAAAACAACATAAATCAGGTACAGAATTTCAGAGTGGGATATCAGATCTTTAGTGTGAAGATACATCTA
CATTAAACCAGGAATCACTAGAACTGACATTTGGACAAGAAAATTTGGAAAATTTTAAAACTGTGAAGGTTGATCATGGAAATTAAAGAG
GAAGGGGCATCAGAAGAAGGGCAGCACTTTCTTCCTACAGCCCAGGCCAATGATCCCGGGGACTGTCAGTTCACAAGTATCCAGAAGACT
CCAAATGAACCGCAGTTGGAATTCATCCTTGCATGCAAGGATCTCGTGGCTCCTGTCCGTGATCGTAAACTGAATACACTGGTGCAGATC
TCCGTAATCCACCCCGTGGAGCAGAGTCTGACAAGATACTCCAGCACCGAAATTGTGGAGGGAACAAGGGACCCACTGTTTTTGACTGGT
GTCACATTCCCATCTGAGTATCCCATCTATGAGGAGACCAAAATAAAACTAACAGTCTATGATGTCAAGGATAAGTCTCATGACACCTTG
GTTCGACTATGCAATGAGGGCGCCCGGAAGATGGAAAGGACTGAGATGATGTACACAATTAACTCCCAGCTGGAATTTAAAATTAAGCCT
TTTCCTTTAGTCTCCTCTTCCCGGTGGTTGGTAAAAAGAGGTGAATTGACAGCCTATGTTGAAGACACTGTGCTTTTCTCAAGAAGGACA
TCCAAACAGCAAGTCTACTTCTTTCTCTTTAACGATGTGCTCATTATCACCAAGAAGAAGAGTGAAGAAAGTTACAACGTCAATGATTAT
TCCTTAAGAGATCAGCTATTGGTGGAATCTTGTGACAATGAAGAGCTTAATTCTTCTCCAGGGAAGAACAGCTCCACAATGCTCTATTCA
AGACAGAGCTCTGCCAGTCACCTCTTTACTCTGACAGTCCTTAGTAACCACGCGAATGAGAAAGTGGAGATGCTACTAGGAGCTGAGACG
CAGAGCGAGCGAGCCCGCTGGATAACTGCCCTGGGACACAGCAGCGGGAAGCCGCCTGCAGACCGAACCTCACTGACCCAGGTGGAAATC
GTTAGGTCATTTACTGCTAAGCAGCCAGATGAACTCTCCCTGCAGGTGGCTGACGTCGTCCTCATCTATCAACGTGTCAGCGATGGCTGG
TATGAGGGGGAACGACTACGAGATGGAGAAAGAGGCTGGTTTCCTATGGAATGTGCCAAGGAGATAACATGTCAAGCTACAATTGATAAG
AATGTGGAGAGAATGGGACGCTTGCTAGGACTGGAGACCAACGTGTAGTCTCTCAGATGGTCTTTTGTTACTGCAAGATTTGCACGACAC
TTACCGGGCTGGTTGGTTCTGGGCTAGTTTTATTGTTAATTTTGTCACAGCCTATTTAATTAAAAGAACGAAAACACTTGCCTTTAAGCT
TGCCAGGTTGTTCTGCTCTCTCATGAGAAGAGCTTGGATACAGTGAGTTTGCACAGCTCAGTTTTTACCTAACCACACACTTGCAGACCT
CCTGAGGTACACAGAATAGCTGAGCAGTTCACTTCAGGGATCAGGTCATCTCTGCTCCTCCTAGTTTCACCATGTTCTGGCAATAAAAAA
CACATATTATATCCTGGTTTTCTCTATCCTTGCATTACTAAGGTGACTGTCTCTCTTTATACATCCTTGTATGGTTCTCCCAGTATTAGC
AAGATTGTATATCTGTAAAGAATGTCCAGTTTTGTAAATATTTCCCTGCCTTTTTTTTTCTTTTTTTACATCTGATTTTAATGCTTCGTT
AACTTCAAAAGGAACTGGTAGAGTTCAGAAGGTGAGCTGTTGTTTTTCTAAACCTCTTCCCAGGAAGGGGACATTGACACTTGAATTTTT
GTCACCTTTTTCCTCATTAGAAGGAAAGTAGAAAGCCTTACTTTAGGATTTTTAAAAAAAAATCCATCTCACCCCATATTGTTCTTAAAT
AAGTATAGACTAATTAACCTAAGCTACCTTTAACAACGTAGAATTTAGATGGGTTCATATATGTGAGAAAAACCTGAATATAGGACAGGG
GTCCTACTTTTTTCCCCACCTCTGTCGCCCAGGCTAGAGTATAGTGGTGTGATCTTGGCCCACTGCAACCTCTGCTTCCTAGGTTCAAGT
GATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTGTAAGAGTATGCCACCACGCCCAGCTACTTTTTGTATTTTTAGTAGAGACAGGG
TTTCATCATGTTGGCCAGGATGGTCTCTTAACTCCTGCCCTCAAGTGATCCACCAGAGAGGAGATCCTCGGCCTCCCCAAGTGCTGGGAT

>39781_39781_6_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000509777_ARHGEF26_chr3_153935657_ENST00000465093_length(amino acids)=382AA_BP=126
MIMEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTR
DPLFLTGVTFPSEYPIYEETKIKLTVYDVKDKSHDTLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDT
VLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVE
MLLGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEIT

--------------------------------------------------------------
>39781_39781_7_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000513000_ARHGEF26_chr3_153935657_ENST00000356448_length(transcript)=3931nt_BP=806nt
CACACGCTCGCAAGCGAACGCAGGAAAGTCAGGCTAAAAGTGTCTGCTGCTGCTGCCGCCCCCCACTCCGCCTCCGGGAGAGAATACAAA
GAAATGGTGTTACCTGGCAAGAGGTCTTCTGTCTTTTATGAAAAATTAGACAAAGGCTTTACAGGAGGCATAGTACTGGAAATCTGCTCC
TGATGAGGTCTCAGAAAGCTTCCACTCGTGGTGGAAGGCAAAGGAGGAGCAGGCACATCACATGAGCCTTGAAACCAGCGAAACAATAAT
CAAAGAGCAGTTCTGTCAAAGAAAACAACATAAATCAGGTACAGAATTTCAGAGTGGGATATCAGATCTTTAGTGTGAAGATACATCTAC
ATTAAACCAGGAATCACTAGAACTGACATTTGGACAAGAAAATTTGGAAAATTTTAAAACTGTGAAGGTTGATCATGGAAATTAAAGAGG
AAGGGGCATCAGAAGAAGGGCAGCACTTTCTTCCTACAGCCCAGGCCAATGATCCCGGGGACTGTCAGTTCACAAGTATCCAGAAGACTC
CAAATGAACCGCAGTTGGAATTCATCCTTGCATGCAAGGATCTCGTGGCTCCTGTCCGTGATCGTAAACTGAATACACTGGTGCAGATCT
CCGTAATCCACCCCGTGGAGCAGAGTCTGACAAGATACTCCAGCACCGAAATTGTGGAGGGAACAAGGGACCCACTGTTTTTGACTGGTG
TCACATTCCCATCTGAGTATCCCATCTATGAGGAGACCAAAATAAAACTAACAGTCTATGATGTCAAGGATAAGTCTCATGACACCTTGG
TTCGACTATGCAATGAGGGCGCCCGGAAGATGGAAAGGACTGAGATGATGTACACAATTAACTCCCAGCTGGAATTTAAAATTAAGCCTT
TTCCTTTAGTCTCCTCTTCCCGGTGGTTGGTAAAAAGAGGTGAATTGACAGCCTATGTTGAAGACACTGTGCTTTTCTCAAGAAGGACAT
CCAAACAGCAAGTCTACTTCTTTCTCTTTAACGATGTGCTCATTATCACCAAGAAGAAGAGTGAAGAAAGTTACAACGTCAATGATTATT
CCTTAAGAGATCAGCTATTGGTGGAATCTTGTGACAATGAAGAGCTTAATTCTTCTCCAGGGAAGAACAGCTCCACAATGCTCTATTCAA
GACAGAGCTCTGCCAGTCACCTCTTTACTCTGACAGTCCTTAGTAACCACGCGAATGAGAAAGTGGAGATGCTACTAGGAGCTGAGACGC
AGAGCGAGCGAGCCCGCTGGATAACTGCCCTGGGACACAGCAGCGGGAAGCCGCCTGCAGACCGAACCTCACTGACCCAGGTGGAAATCG
TTAGGTCATTTACTGCTAAGCAGCCAGATGAACTCTCCCTGCAGGTGGCTGACGTCGTCCTCATCTATCAACGTGTCAGCGATGGCTGGT
ATGAGGGGGAACGACTACGAGATGGAGAAAGAGGCTGGTTTCCTATGGAATGTGCCAAGGAGATAACATGTCAAGCTACAATTGATAAGA
ATGTGGAGAGAATGGGACGCTTGCTAGGACTGGAGACCAACGTGTAGTCTCTCAGATGGTCTTTTGTTACTGCAAGATTTGCACGACACT
TACCGGGCTGGTTGGTTCTGGGCTAGTTTTATTGTTAATTTTGTCACAGCCTATTTAATTAAAAGAACGAAAACACTTGCCTTTAAGCTT
GCCAGGTTGTTCTGCTCTCTCATGAGAAGAGCTTGGATACAGTGAGTTTGCACAGCTCAGTTTTTACCTAACCACACACTTGCAGACCTC
CTGAGGTACACAGAATAGCTGAGCAGTTCACTTCAGGGATCAGGTCATCTCTGCTCCTCCTAGTTTCACCATGTTCTGGCAATAAAAAAC
ACATATTATATCCTGGTTTTCTCTATCCTTGCATTACTAAGGTGACTGTCTCTCTTTATACATCCTTGTATGGTTCTCCCAGTATTAGCA
AGATTGTATATCTGTAAAGAATGTCCAGTTTTGTAAATATTTCCCTGCCTTTTTTTTTCTTTTTTTACATCTGATTTTAATGCTTCGTTA
ACTTCAAAAGGAACTGGTAGAGTTCAGAAGGTGAGCTGTTGTTTTTCTAAACCTCTTCCCAGGAAGGGGACATTGACACTTGAATTTTTG
TCACCTTTTTCCTCATTAGAAGGAAAGTAGAAAGCCTTACTTTAGGATTTTTAAAAAAAAATCCATCTCACCCCATATTGTTCTTAAATA
AGTATAGACTAATTAACCTAAGCTACCTTTAACAACGTAGAATTTAGATGGGTTCATATATGTGAGAAAAACCTGAATATAGGACAGGGG
TCCTACTTTTTTCCCCACCTCTGTCGCCCAGGCTAGAGTATAGTGGTGTGATCTTGGCCCACTGCAACCTCTGCTTCCTAGGTTCAAGTG
ATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTGTAAGAGTATGCCACCACGCCCAGCTACTTTTTGTATTTTTAGTAGAGACAGGGT
TTCATCATGTTGGCCAGGATGGTCTCTTAACTCCTGCCCTCAAGTGATCCACCAGAGAGGAGATCCTCGGCCTCCCCAAGTGCTGGGATT
ATAGGCATGAGCCACCGTGCCCAGCCTACTTTCTAATTAATTAAAAAAAAAAAAAAAAAAAAAAAAAAACCTTCCCAAATGAGCTGATAA
AAAACTGACGTGAGGCTGCTTTGCCTTCAATAATACCTAGTTTTCAGCTGTTCCAACTCGTTTCCAAATAGAAATTAGCTGGAACACACT
ACAGTAATCTCAAGGAAGGGAAAATTAGGCCTTAAAAGATACCAAGAAGTCAGCATGGTACCCAATTGAAACCTTTTGACCTTAGTGGGA
ATTCATTCTATTTGCACTAAAAGCCTTAACTTGCTGTATTCAGAGTCCCTCTTAACTGTGAGTTTCTATAGAACTTTACTTTTTCCACTA
GTGCACAGAGAGAGAAAGGTTATCTTAATAGTCGGTTTCATGGAGATGAAGGATGGGAGATTAAGAGGGGGGAAATGATTTTTACTGGCA
GCTATATTCCCTCTCTGTTCTATTTGCTTTAACAAAGGGATAAAACCTGGCAAAGTGTACATTATTGGAGGACTCAAATCTGTATGTGAC
ATGTCCCAACTACTGTCCGCTAACTAGTTATCCAAATTGTAAAGCTACAGAAGCCCAGTTGAGGGGTAAGTGTGCCTGGCTCACACAGCC
TGCACCCTGTCACCTCGGCAATGAGCCAGTGTGGGGCACTGGGGACTTCTAACCCTTGGATTGCTCTTTTTGACCTGTGCATACCTTCTA
ATTGTAAAATATATTTCAGACCGTGAGTACCTTGAGATCTGAGCAACTGTGTTAATGAAGTAATAGCAATGGTCCACAGTGAAAGATGTG
TTGGGGTTTGCAAAACAAGCATTCCGTCACCTCTTTAATAATGTCACAGACTTTTTAAAAGAGAGGCTATCAAGTTGTAATATAATCTGT
CATGTTTTATTTAGGAAGGAAGGTAAATTTGTGCTTGCACGGGGATCATTTTGTATTATTTTTGCTAATACCCAGTTGAAGCTAAAAAGC
AACTATTTGAATCCTGTGAATTAATTTATAAGAATGTTAAACAGCTTTGGAAATACATGCATCTTATGAATCATAGCCTTATTTAGCAAG
ATCAATGTTAAAGTGTTGTTATATGGCAAGTATTTAACACATTCACAGTGTTTGTTTGATTTCAACTGTGAATTGTCTTAAGTTTTTTCA
AACCTAGTTGTTTCTATGGACACCTGCTCTGAATTGTACATTGACTTCATTACTAAAGAACAAAAATGTTCATTTTTGTCCCAGTAAATT

>39781_39781_7_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000513000_ARHGEF26_chr3_153935657_ENST00000356448_length(amino acids)=382AA_BP=126
MIMEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTR
DPLFLTGVTFPSEYPIYEETKIKLTVYDVKDKSHDTLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDT
VLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVE
MLLGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEIT

--------------------------------------------------------------
>39781_39781_8_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000513000_ARHGEF26_chr3_153935657_ENST00000465093_length(transcript)=2679nt_BP=806nt
CACACGCTCGCAAGCGAACGCAGGAAAGTCAGGCTAAAAGTGTCTGCTGCTGCTGCCGCCCCCCACTCCGCCTCCGGGAGAGAATACAAA
GAAATGGTGTTACCTGGCAAGAGGTCTTCTGTCTTTTATGAAAAATTAGACAAAGGCTTTACAGGAGGCATAGTACTGGAAATCTGCTCC
TGATGAGGTCTCAGAAAGCTTCCACTCGTGGTGGAAGGCAAAGGAGGAGCAGGCACATCACATGAGCCTTGAAACCAGCGAAACAATAAT
CAAAGAGCAGTTCTGTCAAAGAAAACAACATAAATCAGGTACAGAATTTCAGAGTGGGATATCAGATCTTTAGTGTGAAGATACATCTAC
ATTAAACCAGGAATCACTAGAACTGACATTTGGACAAGAAAATTTGGAAAATTTTAAAACTGTGAAGGTTGATCATGGAAATTAAAGAGG
AAGGGGCATCAGAAGAAGGGCAGCACTTTCTTCCTACAGCCCAGGCCAATGATCCCGGGGACTGTCAGTTCACAAGTATCCAGAAGACTC
CAAATGAACCGCAGTTGGAATTCATCCTTGCATGCAAGGATCTCGTGGCTCCTGTCCGTGATCGTAAACTGAATACACTGGTGCAGATCT
CCGTAATCCACCCCGTGGAGCAGAGTCTGACAAGATACTCCAGCACCGAAATTGTGGAGGGAACAAGGGACCCACTGTTTTTGACTGGTG
TCACATTCCCATCTGAGTATCCCATCTATGAGGAGACCAAAATAAAACTAACAGTCTATGATGTCAAGGATAAGTCTCATGACACCTTGG
TTCGACTATGCAATGAGGGCGCCCGGAAGATGGAAAGGACTGAGATGATGTACACAATTAACTCCCAGCTGGAATTTAAAATTAAGCCTT
TTCCTTTAGTCTCCTCTTCCCGGTGGTTGGTAAAAAGAGGTGAATTGACAGCCTATGTTGAAGACACTGTGCTTTTCTCAAGAAGGACAT
CCAAACAGCAAGTCTACTTCTTTCTCTTTAACGATGTGCTCATTATCACCAAGAAGAAGAGTGAAGAAAGTTACAACGTCAATGATTATT
CCTTAAGAGATCAGCTATTGGTGGAATCTTGTGACAATGAAGAGCTTAATTCTTCTCCAGGGAAGAACAGCTCCACAATGCTCTATTCAA
GACAGAGCTCTGCCAGTCACCTCTTTACTCTGACAGTCCTTAGTAACCACGCGAATGAGAAAGTGGAGATGCTACTAGGAGCTGAGACGC
AGAGCGAGCGAGCCCGCTGGATAACTGCCCTGGGACACAGCAGCGGGAAGCCGCCTGCAGACCGAACCTCACTGACCCAGGTGGAAATCG
TTAGGTCATTTACTGCTAAGCAGCCAGATGAACTCTCCCTGCAGGTGGCTGACGTCGTCCTCATCTATCAACGTGTCAGCGATGGCTGGT
ATGAGGGGGAACGACTACGAGATGGAGAAAGAGGCTGGTTTCCTATGGAATGTGCCAAGGAGATAACATGTCAAGCTACAATTGATAAGA
ATGTGGAGAGAATGGGACGCTTGCTAGGACTGGAGACCAACGTGTAGTCTCTCAGATGGTCTTTTGTTACTGCAAGATTTGCACGACACT
TACCGGGCTGGTTGGTTCTGGGCTAGTTTTATTGTTAATTTTGTCACAGCCTATTTAATTAAAAGAACGAAAACACTTGCCTTTAAGCTT
GCCAGGTTGTTCTGCTCTCTCATGAGAAGAGCTTGGATACAGTGAGTTTGCACAGCTCAGTTTTTACCTAACCACACACTTGCAGACCTC
CTGAGGTACACAGAATAGCTGAGCAGTTCACTTCAGGGATCAGGTCATCTCTGCTCCTCCTAGTTTCACCATGTTCTGGCAATAAAAAAC
ACATATTATATCCTGGTTTTCTCTATCCTTGCATTACTAAGGTGACTGTCTCTCTTTATACATCCTTGTATGGTTCTCCCAGTATTAGCA
AGATTGTATATCTGTAAAGAATGTCCAGTTTTGTAAATATTTCCCTGCCTTTTTTTTTCTTTTTTTACATCTGATTTTAATGCTTCGTTA
ACTTCAAAAGGAACTGGTAGAGTTCAGAAGGTGAGCTGTTGTTTTTCTAAACCTCTTCCCAGGAAGGGGACATTGACACTTGAATTTTTG
TCACCTTTTTCCTCATTAGAAGGAAAGTAGAAAGCCTTACTTTAGGATTTTTAAAAAAAAATCCATCTCACCCCATATTGTTCTTAAATA
AGTATAGACTAATTAACCTAAGCTACCTTTAACAACGTAGAATTTAGATGGGTTCATATATGTGAGAAAAACCTGAATATAGGACAGGGG
TCCTACTTTTTTCCCCACCTCTGTCGCCCAGGCTAGAGTATAGTGGTGTGATCTTGGCCCACTGCAACCTCTGCTTCCTAGGTTCAAGTG
ATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTGTAAGAGTATGCCACCACGCCCAGCTACTTTTTGTATTTTTAGTAGAGACAGGGT
TTCATCATGTTGGCCAGGATGGTCTCTTAACTCCTGCCCTCAAGTGATCCACCAGAGAGGAGATCCTCGGCCTCCCCAAGTGCTGGGATT

>39781_39781_8_INPP4B-ARHGEF26_INPP4B_chr4_143324090_ENST00000513000_ARHGEF26_chr3_153935657_ENST00000465093_length(amino acids)=382AA_BP=126
MIMEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTR
DPLFLTGVTFPSEYPIYEETKIKLTVYDVKDKSHDTLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDT
VLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVE
MLLGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEIT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for INPP4B-ARHGEF26


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for INPP4B-ARHGEF26


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for INPP4B-ARHGEF26


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource