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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:INPP5B-TRIT1 (FusionGDB2 ID:39825)

Fusion Gene Summary for INPP5B-TRIT1

Fusion gene summary

Fusion gene information	Fusion gene name: INPP5B-TRIT1
	Fusion gene ID: 39825
		Hgene	Tgene
	Gene symbol	INPP5B	TRIT1
	Gene ID	3633	54802
	Gene name	inositol polyphosphate-5-phosphatase B	tRNA isopentenyltransferase 1
	Synonyms	5PTase	COXPD35\|GRO1\|IPPT\|IPT\|IPTase\|MOD5\|hGRO1
	Cytomap	1p34.3	1p34.2
	Type of gene	protein-coding	protein-coding
	Description	type II inositol 1,4,5-trisphosphate 5-phosphataseinositol polyphosphate-5-phosphatase, 75kDaphosphoinositide 5-phosphatase	tRNA dimethylallyltransferaseIPP transferaseisopentenyl-diphosphate:tRNA isopentenyltransferasetRNA dimethylallyltransferase, mitochondrialtRNA isopentenylpyrophosphate transferase
	Modification date	20200313	20200313
	UniProtAcc	P32019	.
	Ensembl transtripts involved in fusion gene	ENST00000373023, ENST00000373024, ENST00000373026, ENST00000373027, ENST00000373021, ENST00000458109, ENST00000467066,	ENST00000491865, ENST00000537223, ENST00000537440, ENST00000541099, ENST00000544981, ENST00000545233, ENST00000316891, ENST00000372818, ENST00000441669,
Fusion gene scores	* DoF score	6 X 8 X 4=192	5 X 5 X 3=75
	# samples	9	6
	** MAII score	log2(9/192*10)=-1.09310940439148 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(6/75*10)=-0.321928094887362 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: INPP5B [Title/Abstract] AND TRIT1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	INPP5B(38351310)-TRIT1(40313332), # samples:2
Anticipated loss of major functional domain due to fusion event.	INPP5B-TRIT1 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF. INPP5B-TRIT1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. INPP5B-TRIT1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. INPP5B-TRIT1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	INPP5B	GO:0046856	phosphatidylinositol dephosphorylation	7721860

Fusion gene breakpoints across INPP5B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TRIT1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	OV	TCGA-25-1633-01A	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
ChimerDB4	OV	TCGA-25-1633	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-

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Fusion Gene ORF analysis for INPP5B-TRIT1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000373023	ENST00000491865	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373023	ENST00000491865	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373023	ENST00000537223	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373023	ENST00000537223	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373023	ENST00000537440	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373023	ENST00000537440	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373023	ENST00000541099	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373023	ENST00000541099	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373023	ENST00000544981	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373023	ENST00000544981	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373023	ENST00000545233	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373023	ENST00000545233	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373024	ENST00000491865	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373024	ENST00000491865	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373024	ENST00000537223	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373024	ENST00000537223	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373024	ENST00000537440	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373024	ENST00000537440	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373024	ENST00000541099	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373024	ENST00000541099	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373024	ENST00000544981	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373024	ENST00000544981	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373024	ENST00000545233	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373024	ENST00000545233	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373026	ENST00000491865	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373026	ENST00000491865	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373026	ENST00000537223	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373026	ENST00000537223	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373026	ENST00000537440	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373026	ENST00000537440	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373026	ENST00000541099	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373026	ENST00000541099	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373026	ENST00000544981	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373026	ENST00000544981	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373026	ENST00000545233	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373026	ENST00000545233	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373027	ENST00000491865	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373027	ENST00000491865	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373027	ENST00000537223	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373027	ENST00000537223	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373027	ENST00000537440	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373027	ENST00000537440	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373027	ENST00000541099	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373027	ENST00000541099	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373027	ENST00000544981	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373027	ENST00000544981	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373027	ENST00000545233	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
5CDS-intron	ENST00000373027	ENST00000545233	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
Frame-shift	ENST00000373023	ENST00000316891	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
Frame-shift	ENST00000373023	ENST00000316891	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
Frame-shift	ENST00000373023	ENST00000372818	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
Frame-shift	ENST00000373023	ENST00000372818	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
Frame-shift	ENST00000373023	ENST00000441669	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
Frame-shift	ENST00000373023	ENST00000441669	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
Frame-shift	ENST00000373024	ENST00000316891	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
Frame-shift	ENST00000373024	ENST00000316891	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
Frame-shift	ENST00000373024	ENST00000372818	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
Frame-shift	ENST00000373024	ENST00000372818	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
Frame-shift	ENST00000373024	ENST00000441669	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
Frame-shift	ENST00000373024	ENST00000441669	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
In-frame	ENST00000373026	ENST00000316891	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
In-frame	ENST00000373026	ENST00000316891	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
In-frame	ENST00000373026	ENST00000372818	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
In-frame	ENST00000373026	ENST00000372818	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
In-frame	ENST00000373026	ENST00000441669	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
In-frame	ENST00000373026	ENST00000441669	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
In-frame	ENST00000373027	ENST00000316891	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
In-frame	ENST00000373027	ENST00000316891	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
In-frame	ENST00000373027	ENST00000372818	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
In-frame	ENST00000373027	ENST00000372818	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
In-frame	ENST00000373027	ENST00000441669	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
In-frame	ENST00000373027	ENST00000441669	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000373021	ENST00000316891	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000373021	ENST00000316891	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000373021	ENST00000372818	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000373021	ENST00000372818	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000373021	ENST00000441669	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000373021	ENST00000441669	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000458109	ENST00000316891	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000458109	ENST00000316891	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000458109	ENST00000372818	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000458109	ENST00000372818	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000458109	ENST00000441669	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000458109	ENST00000441669	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000467066	ENST00000316891	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000467066	ENST00000316891	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000467066	ENST00000372818	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000467066	ENST00000372818	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000467066	ENST00000441669	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-3CDS	ENST00000467066	ENST00000441669	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000373021	ENST00000491865	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000373021	ENST00000491865	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000373021	ENST00000537223	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000373021	ENST00000537223	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000373021	ENST00000537440	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000373021	ENST00000537440	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000373021	ENST00000541099	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000373021	ENST00000541099	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000373021	ENST00000544981	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000373021	ENST00000544981	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000373021	ENST00000545233	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000373021	ENST00000545233	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000458109	ENST00000491865	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000458109	ENST00000491865	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000458109	ENST00000537223	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000458109	ENST00000537223	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000458109	ENST00000537440	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000458109	ENST00000537440	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000458109	ENST00000541099	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000458109	ENST00000541099	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000458109	ENST00000544981	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000458109	ENST00000544981	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000458109	ENST00000545233	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000458109	ENST00000545233	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000467066	ENST00000491865	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000467066	ENST00000491865	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000467066	ENST00000537223	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000467066	ENST00000537223	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000467066	ENST00000537440	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000467066	ENST00000537440	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000467066	ENST00000541099	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000467066	ENST00000541099	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000467066	ENST00000544981	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000467066	ENST00000544981	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000467066	ENST00000545233	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-
intron-intron	ENST00000467066	ENST00000545233	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000373026	INPP5B	chr1	38351310	-	ENST00000441669	TRIT1	chr1	40313332	-	2842	1560	1	2148	715
ENST00000373026	INPP5B	chr1	38351310	-	ENST00000316891	TRIT1	chr1	40313332	-	2842	1560	1	2148	715
ENST00000373026	INPP5B	chr1	38351310	-	ENST00000372818	TRIT1	chr1	40313332	-	2764	1560	1	2070	689
ENST00000373027	INPP5B	chr1	38351310	-	ENST00000441669	TRIT1	chr1	40313332	-	2146	864	37	1452	471
ENST00000373027	INPP5B	chr1	38351310	-	ENST00000316891	TRIT1	chr1	40313332	-	2146	864	37	1452	471
ENST00000373027	INPP5B	chr1	38351310	-	ENST00000372818	TRIT1	chr1	40313332	-	2068	864	37	1374	445
ENST00000373026	INPP5B	chr1	38351309	-	ENST00000441669	TRIT1	chr1	40313332	-	2842	1560	1	2148	715
ENST00000373026	INPP5B	chr1	38351309	-	ENST00000316891	TRIT1	chr1	40313332	-	2842	1560	1	2148	715
ENST00000373026	INPP5B	chr1	38351309	-	ENST00000372818	TRIT1	chr1	40313332	-	2764	1560	1	2070	689
ENST00000373027	INPP5B	chr1	38351309	-	ENST00000441669	TRIT1	chr1	40313332	-	2146	864	37	1452	471
ENST00000373027	INPP5B	chr1	38351309	-	ENST00000316891	TRIT1	chr1	40313332	-	2146	864	37	1452	471
ENST00000373027	INPP5B	chr1	38351309	-	ENST00000372818	TRIT1	chr1	40313332	-	2068	864	37	1374	445

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000373026	ENST00000441669	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-	0.001011846	0.9989881
ENST00000373026	ENST00000316891	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-	0.001011846	0.9989881
ENST00000373026	ENST00000372818	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-	0.001139978	0.99886
ENST00000373027	ENST00000441669	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-	0.000712551	0.9992874
ENST00000373027	ENST00000316891	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-	0.000712551	0.9992874
ENST00000373027	ENST00000372818	INPP5B	chr1	38351310	-	TRIT1	chr1	40313332	-	0.000764735	0.9992353
ENST00000373026	ENST00000441669	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-	0.001011846	0.9989881
ENST00000373026	ENST00000316891	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-	0.001011846	0.9989881
ENST00000373026	ENST00000372818	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-	0.001139978	0.99886
ENST00000373027	ENST00000441669	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-	0.000712551	0.9992874
ENST00000373027	ENST00000316891	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-	0.000712551	0.9992874
ENST00000373027	ENST00000372818	INPP5B	chr1	38351309	-	TRIT1	chr1	40313332	-	0.000764735	0.9992353

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Fusion Genomic Features for INPP5B-TRIT1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for INPP5B-TRIT1

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:38351310/chr1:40313332)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
INPP5B P32019	.
FUNCTION: Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5-trisphosphate (PtIns(1,4,5)P3), and thereby modulates cellular signaling events. {ECO:0000269\|PubMed:7721860}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373023

22_148

519

994.0

Domain

Note=PH

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373024

22_148

439

914.0

Domain

Note=PH

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373026

22_148

519

994.0

Domain

Note=PH

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373027

22_148

275

750.0

Domain

Note=PH

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373023

22_148

519

994.0

Domain

Note=PH

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373024

22_148

439

914.0

Domain

Note=PH

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373026

22_148

519

994.0

Domain

Note=PH

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373027

22_148

275

750.0

Domain

Note=PH

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373023

459_460

519

994.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373026

459_460

519

994.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373023

459_460

519

994.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373026

459_460

519

994.0

Region

Note=Substrate binding

Tgene

TRIT1

chr1:38351309

chr1:40313332

ENST00000316891

395_425

271

468.0

Zinc finger

Note=Matrin-type

Tgene

TRIT1

chr1:38351309

chr1:40313332

ENST00000372818

395_425

271

442.0

Zinc finger

Note=Matrin-type

Tgene

TRIT1

chr1:38351309

chr1:40313332

ENST00000441669

395_425

189

386.0

Zinc finger

Note=Matrin-type

Tgene

TRIT1

chr1:38351310

chr1:40313332

ENST00000316891

395_425

271

468.0

Zinc finger

Note=Matrin-type

Tgene

TRIT1

chr1:38351310

chr1:40313332

ENST00000372818

395_425

271

442.0

Zinc finger

Note=Matrin-type

Tgene

TRIT1

chr1:38351310

chr1:40313332

ENST00000441669

395_425

189

386.0

Zinc finger

Note=Matrin-type

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373023

821_993

519

994.0

Domain

Rho-GAP

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373024

821_993

439

914.0

Domain

Rho-GAP

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373026

821_993

519

994.0

Domain

Rho-GAP

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373027

821_993

275

750.0

Domain

Rho-GAP

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373023

821_993

519

994.0

Domain

Rho-GAP

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373024

821_993

439

914.0

Domain

Rho-GAP

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373026

821_993

519

994.0

Domain

Rho-GAP

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373027

821_993

275

750.0

Domain

Rho-GAP

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373023

342_668

519

994.0

Region

5-phosphatase

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373023

582_583

519

994.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373023

596_598

519

994.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373023

669_782

519

994.0

Region

ASH

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373024

342_668

439

914.0

Region

5-phosphatase

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373024

459_460

439

914.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373024

582_583

439

914.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373024

596_598

439

914.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373024

669_782

439

914.0

Region

ASH

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373026

342_668

519

994.0

Region

5-phosphatase

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373026

582_583

519

994.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373026

596_598

519

994.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373026

669_782

519

994.0

Region

ASH

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373027

342_668

275

750.0

Region

5-phosphatase

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373027

459_460

275

750.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373027

582_583

275

750.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373027

596_598

275

750.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351309

chr1:40313332

ENST00000373027

669_782

275

750.0

Region

ASH

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373023

342_668

519

994.0

Region

5-phosphatase

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373023

582_583

519

994.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373023

596_598

519

994.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373023

669_782

519

994.0

Region

ASH

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373024

342_668

439

914.0

Region

5-phosphatase

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373024

459_460

439

914.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373024

582_583

439

914.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373024

596_598

439

914.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373024

669_782

439

914.0

Region

ASH

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373026

342_668

519

994.0

Region

5-phosphatase

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373026

582_583

519

994.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373026

596_598

519

994.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373026

669_782

519

994.0

Region

ASH

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373027

342_668

275

750.0

Region

5-phosphatase

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373027

459_460

275

750.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373027

582_583

275

750.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373027

596_598

275

750.0

Region

Note=Substrate binding

Hgene

INPP5B

chr1:38351310

chr1:40313332

ENST00000373027

669_782

275

750.0

Region

ASH

Tgene

TRIT1

chr1:38351309

chr1:40313332

ENST00000316891

32_37

271

468.0

Region

Substrate binding

Tgene

TRIT1

chr1:38351309

chr1:40313332

ENST00000372818

32_37

271

442.0

Region

Substrate binding

Tgene

TRIT1

chr1:38351309

chr1:40313332

ENST00000441669

32_37

189

386.0

Region

Substrate binding

Tgene

TRIT1

chr1:38351310

chr1:40313332

ENST00000316891

32_37

271

468.0

Region

Substrate binding

Tgene

TRIT1

chr1:38351310

chr1:40313332

ENST00000372818

32_37

271

442.0

Region

Substrate binding

Tgene

TRIT1

chr1:38351310

chr1:40313332

ENST00000441669

32_37

189

386.0

Region

Substrate binding

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Fusion Gene Sequence for INPP5B-TRIT1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>39825_39825_1_INPP5B-TRIT1_INPP5B_chr1_38351309_ENST00000373026_TRIT1_chr1_40313332_ENST00000316891_length(transcript)=2842nt_BP=1560nt
CATGGACCAGTCTGTGGCAATCCAGGAGACGCTGGCTGAGGGGGAATACTGCGTCATCGCGGTGCAAGGTGTGCTGTGTGAGGGGGACAG
CCGGCAGAGCCGCCTCCTGGGACTCGTGCGCTACCGCCTGGAGCACGGCGGCCAGGAACACGCTCTCTTCCTCTATACGCACCGGAGGAT
GGCCATTACCGGGGACGATGTCTCTCTGGACCAGATAGTGCCAGTCTCGCGGGATTTTACGCTGGAAGAAGTGTCCCCAGATGGTGAACT
CTACATCCTTGGCTCAGATGTGACCGTCCAGCTGGACACAGCAGAGCTTAGCCTCGTATTCCAACTGCCCTTTGGTTCACAAACCAGGAT
GTTCCTCCACGAAGTTGCCAGGGCCTGTCCAGGCTTCGATTCTGCGACCCGGGATCCTGAATTCCTGTGGCTGTCTCGGTATAGGTGCGC
AGAGCTGGAGCTGGAGATGCCAACGCCGCGCGGTTGTAACTCGGCCCTAGTTACCTGGCCAGGGTACGCGACAATTGGCGGAGGCAGGTA
TCCGTCCCGGAAGAAACGGTGGGGATTGGAGGAGGCCCGGCCACAGGGGGCGGGCTCCGTTCTGTTTTGGGGCGGAGCGATGGAGAAGAC
AGGCTTTCGATTGATGGAGCGGGCACACGGGGGCGGGTTCGTCTGGGGGCGGAGCGCGCGGGACGGGCGGCGGGATGAGGAGCTTGAGGA
AGCAGGCAGGGAAATGTCTGCCGCCGCCGGCTCTCGGGAGCGCAACACTGCAGGTGGTTCTAACTTTGATGGTTTGAGACCAAATGGGAA
GGGAGTGCCTATGGACCAAAGCTCCAGGGGTCAAGATAAACCAGAAAGCTTGCAACCAAGACAGAATAAATCCAAGTCCGAAATTACTGA
CATGGTTCGCTCCTCCACTATCACAGTGTCGGACAAGGCTCATATTTTATCCATGCAGAAGTTTGGACTGCGAGATACAATTGTGAAATC
ACATCTACTACAGAAAGAAGAGGATTACACCTATATCCAGAACTTCAGGTTTTTTGCGGGAACATACAATGTAAATGGGCAGTCCCCCAA
AGAATGCCTCCGGCTGTGGCTGAGCAATGGTATCCAGGCCCCAGATGTCTATTGTGTAGGGTTCCAGGAGCTTGATCTGAGTAAGGAAGC
TTTTTTCTTTCACGATACCCCAAAGGAGGAAGAGTGGTTCAAAGCTGTGTCAGAGGGTCTTCATCCAGATGCCAAATATGCAAAGGTGAA
GCTTATCCGACTGGTTGGGATTATGCTGCTGTTATATGTCAAACAGGAGCATGCAGCTTATATCTCAGAAGTGGAAGCCGAGACTGTGGG
GACAGGAATCATGGGGAGGATGGGCAACAAGGGAGGCGTGGCGATCAGGTTCCAGTTCCACAACACCAGCATCTGCGTTGTGAATTCTCA
CTTGGCAGCCCACATTGAAGAGTATGAGAGGAGGAACCAGGACTATAAGGACATTTGTTCTCGAATGCAGTTTTGTCAGCCTGACCCAAG
CCTTCCCCCTCTCACCATCAGCAACCATGACCAGGACTATCAACATGGTATCTTCCAATCAATTGGCTTCAAGGAATTTCACGAGTACCT
GATCACTGAGGGAAAATGCACACTGGAGACTAGTAACCAGCTTCTAAAGAAAGGTATTGAGGCTCTGAAACAAGTAACTAAGAGATATGC
CCGGAAACAAAACCGATGGGTTAAAAACCGTTTTTTGAGCAGACCTGGTCCCATTGTCCCCCCTGTCTATGGCTTAGAGGTATCTGATGT
CTCGAAGTGGGAAGAGTCTGTTCTTGAACCTGCTCTTGAAATCGTGCAAAGTTTCATCCAGGGCCACAAGCCTACAGCCACTCCAATAAA
GATGCCATACAATGAAGCTGAGAACAAGAGAAGTTATCACCTGTGTGACCTCTGTGATCGAATCATCATTGGGGATCGCGAATGGGCAGC
GCACATAAAATCCAAATCCCACTTGAACCAACTGAAGAAAAGAAGAAGATTGGACTCAGATGCTGTCAACACCATAGAAAGTCAGAGTGT
TTCCCCAGACCATAACAAAGAACCTAAAGAGAAGGGATCCCCAGGGCAGAATGATCAAGAGCTGAAATGCAGCGTTTAAGAGACATGTCC
AGTGGCCTTTGGAAAGGTGGTGGGGATCCAGTTCAGGAGGGAGGGGTATGTTTGTCTCCCAGTCTGGGCAAAGGAGTGCTATGCGGAATT
CTCTGCATAGCAGAAAAGCTCCCACCATTTTCTTTTGATGTGGTTTTAAAGTCTCACGTTCTCTATAATAGAAACAGCAGGTCTTGTCAG
CTCCTTGTGTGGCTGATGTGTCTGGAAATGATGTAGTTCAGGAAAGCATTTTTTTTTTCTTTGAACCTTAAAGGTTCTATTATTAAAAGC
AGCACAGATTCCACATTTTTATACATGAGGATCTTCTTTGTGGTGAATACCAGGATTGACTGCATCCCTTTAAAGAAGTTTTATGTCCCT
GACTCTGGCTAAAATTATCTAATTTCCAGATGCTTTTGTAGATGACTGAAGTATTTGTGAGCCACATATTGGGAGTTCTAGATTTGAGTG
AATGGCAGGAAAGGGCCATCTCCATTGAGATGATTAAGTGAACCAAACTAGTTCTCAGAATTCTACAGAGAAGGAGGGAATCAGACTGAG
GAAGCTGTGACATAGGACTTGAAGACCAAAGACTTTGAAATTTGCGAGCTGCTCATGTGTGAGTTATTATCACTGCTGTCTTTCTATTGA

>39825_39825_1_INPP5B-TRIT1_INPP5B_chr1_38351309_ENST00000373026_TRIT1_chr1_40313332_ENST00000316891_length(amino acids)=715AA_BP=520
MDQSVAIQETLAEGEYCVIAVQGVLCEGDSRQSRLLGLVRYRLEHGGQEHALFLYTHRRMAITGDDVSLDQIVPVSRDFTLEEVSPDGEL
YILGSDVTVQLDTAELSLVFQLPFGSQTRMFLHEVARACPGFDSATRDPEFLWLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGRY
PSRKKRWGLEEARPQGAGSVLFWGGAMEKTGFRLMERAHGGGFVWGRSARDGRRDEELEEAGREMSAAAGSRERNTAGGSNFDGLRPNGK
GVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPK
ECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVG
TGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDQDYQHGIFQSIGFKEFHEYL
ITEGKCTLETSNQLLKKGIEALKQVTKRYARKQNRWVKNRFLSRPGPIVPPVYGLEVSDVSKWEESVLEPALEIVQSFIQGHKPTATPIK

--------------------------------------------------------------
>39825_39825_2_INPP5B-TRIT1_INPP5B_chr1_38351309_ENST00000373026_TRIT1_chr1_40313332_ENST00000372818_length(transcript)=2764nt_BP=1560nt
CATGGACCAGTCTGTGGCAATCCAGGAGACGCTGGCTGAGGGGGAATACTGCGTCATCGCGGTGCAAGGTGTGCTGTGTGAGGGGGACAG
CCGGCAGAGCCGCCTCCTGGGACTCGTGCGCTACCGCCTGGAGCACGGCGGCCAGGAACACGCTCTCTTCCTCTATACGCACCGGAGGAT
GGCCATTACCGGGGACGATGTCTCTCTGGACCAGATAGTGCCAGTCTCGCGGGATTTTACGCTGGAAGAAGTGTCCCCAGATGGTGAACT
CTACATCCTTGGCTCAGATGTGACCGTCCAGCTGGACACAGCAGAGCTTAGCCTCGTATTCCAACTGCCCTTTGGTTCACAAACCAGGAT
GTTCCTCCACGAAGTTGCCAGGGCCTGTCCAGGCTTCGATTCTGCGACCCGGGATCCTGAATTCCTGTGGCTGTCTCGGTATAGGTGCGC
AGAGCTGGAGCTGGAGATGCCAACGCCGCGCGGTTGTAACTCGGCCCTAGTTACCTGGCCAGGGTACGCGACAATTGGCGGAGGCAGGTA
TCCGTCCCGGAAGAAACGGTGGGGATTGGAGGAGGCCCGGCCACAGGGGGCGGGCTCCGTTCTGTTTTGGGGCGGAGCGATGGAGAAGAC
AGGCTTTCGATTGATGGAGCGGGCACACGGGGGCGGGTTCGTCTGGGGGCGGAGCGCGCGGGACGGGCGGCGGGATGAGGAGCTTGAGGA
AGCAGGCAGGGAAATGTCTGCCGCCGCCGGCTCTCGGGAGCGCAACACTGCAGGTGGTTCTAACTTTGATGGTTTGAGACCAAATGGGAA
GGGAGTGCCTATGGACCAAAGCTCCAGGGGTCAAGATAAACCAGAAAGCTTGCAACCAAGACAGAATAAATCCAAGTCCGAAATTACTGA
CATGGTTCGCTCCTCCACTATCACAGTGTCGGACAAGGCTCATATTTTATCCATGCAGAAGTTTGGACTGCGAGATACAATTGTGAAATC
ACATCTACTACAGAAAGAAGAGGATTACACCTATATCCAGAACTTCAGGTTTTTTGCGGGAACATACAATGTAAATGGGCAGTCCCCCAA
AGAATGCCTCCGGCTGTGGCTGAGCAATGGTATCCAGGCCCCAGATGTCTATTGTGTAGGGTTCCAGGAGCTTGATCTGAGTAAGGAAGC
TTTTTTCTTTCACGATACCCCAAAGGAGGAAGAGTGGTTCAAAGCTGTGTCAGAGGGTCTTCATCCAGATGCCAAATATGCAAAGGTGAA
GCTTATCCGACTGGTTGGGATTATGCTGCTGTTATATGTCAAACAGGAGCATGCAGCTTATATCTCAGAAGTGGAAGCCGAGACTGTGGG
GACAGGAATCATGGGGAGGATGGGCAACAAGGGAGGCGTGGCGATCAGGTTCCAGTTCCACAACACCAGCATCTGCGTTGTGAATTCTCA
CTTGGCAGCCCACATTGAAGAGTATGAGAGGAGGAACCAGGACTATAAGGACATTTGTTCTCGAATGCAGTTTTGTCAGCCTGACCCAAG
CCTTCCCCCTCTCACCATCAGCAACCATGACCAGGACTATCAACATGGTATCTTCCAATCAATTGGCTTCAAGGAATTTCACGAGTACCT
GATCACTGAGGGAAAATGCACACTGGAGACTAGTAACCAGCTTCTAAAGAAAGGACCTGGTCCCATTGTCCCCCCTGTCTATGGCTTAGA
GGTATCTGATGTCTCGAAGTGGGAAGAGTCTGTTCTTGAACCTGCTCTTGAAATCGTGCAAAGTTTCATCCAGGGCCACAAGCCTACAGC
CACTCCAATAAAGATGCCATACAATGAAGCTGAGAACAAGAGAAGTTATCACCTGTGTGACCTCTGTGATCGAATCATCATTGGGGATCG
CGAATGGGCAGCGCACATAAAATCCAAATCCCACTTGAACCAACTGAAGAAAAGAAGAAGATTGGACTCAGATGCTGTCAACACCATAGA
AAGTCAGAGTGTTTCCCCAGACCATAACAAAGAACCTAAAGAGAAGGGATCCCCAGGGCAGAATGATCAAGAGCTGAAATGCAGCGTTTA
AGAGACATGTCCAGTGGCCTTTGGAAAGGTGGTGGGGATCCAGTTCAGGAGGGAGGGGTATGTTTGTCTCCCAGTCTGGGCAAAGGAGTG
CTATGCGGAATTCTCTGCATAGCAGAAAAGCTCCCACCATTTTCTTTTGATGTGGTTTTAAAGTCTCACGTTCTCTATAATAGAAACAGC
AGGTCTTGTCAGCTCCTTGTGTGGCTGATGTGTCTGGAAATGATGTAGTTCAGGAAAGCATTTTTTTTTTCTTTGAACCTTAAAGGTTCT
ATTATTAAAAGCAGCACAGATTCCACATTTTTATACATGAGGATCTTCTTTGTGGTGAATACCAGGATTGACTGCATCCCTTTAAAGAAG
TTTTATGTCCCTGACTCTGGCTAAAATTATCTAATTTCCAGATGCTTTTGTAGATGACTGAAGTATTTGTGAGCCACATATTGGGAGTTC
TAGATTTGAGTGAATGGCAGGAAAGGGCCATCTCCATTGAGATGATTAAGTGAACCAAACTAGTTCTCAGAATTCTACAGAGAAGGAGGG
AATCAGACTGAGGAAGCTGTGACATAGGACTTGAAGACCAAAGACTTTGAAATTTGCGAGCTGCTCATGTGTGAGTTATTATCACTGCTG

>39825_39825_2_INPP5B-TRIT1_INPP5B_chr1_38351309_ENST00000373026_TRIT1_chr1_40313332_ENST00000372818_length(amino acids)=689AA_BP=520
MDQSVAIQETLAEGEYCVIAVQGVLCEGDSRQSRLLGLVRYRLEHGGQEHALFLYTHRRMAITGDDVSLDQIVPVSRDFTLEEVSPDGEL
YILGSDVTVQLDTAELSLVFQLPFGSQTRMFLHEVARACPGFDSATRDPEFLWLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGRY
PSRKKRWGLEEARPQGAGSVLFWGGAMEKTGFRLMERAHGGGFVWGRSARDGRRDEELEEAGREMSAAAGSRERNTAGGSNFDGLRPNGK
GVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPK
ECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVG
TGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDQDYQHGIFQSIGFKEFHEYL
ITEGKCTLETSNQLLKKGPGPIVPPVYGLEVSDVSKWEESVLEPALEIVQSFIQGHKPTATPIKMPYNEAENKRSYHLCDLCDRIIIGDR

--------------------------------------------------------------
>39825_39825_3_INPP5B-TRIT1_INPP5B_chr1_38351309_ENST00000373026_TRIT1_chr1_40313332_ENST00000441669_length(transcript)=2842nt_BP=1560nt
CATGGACCAGTCTGTGGCAATCCAGGAGACGCTGGCTGAGGGGGAATACTGCGTCATCGCGGTGCAAGGTGTGCTGTGTGAGGGGGACAG
CCGGCAGAGCCGCCTCCTGGGACTCGTGCGCTACCGCCTGGAGCACGGCGGCCAGGAACACGCTCTCTTCCTCTATACGCACCGGAGGAT
GGCCATTACCGGGGACGATGTCTCTCTGGACCAGATAGTGCCAGTCTCGCGGGATTTTACGCTGGAAGAAGTGTCCCCAGATGGTGAACT
CTACATCCTTGGCTCAGATGTGACCGTCCAGCTGGACACAGCAGAGCTTAGCCTCGTATTCCAACTGCCCTTTGGTTCACAAACCAGGAT
GTTCCTCCACGAAGTTGCCAGGGCCTGTCCAGGCTTCGATTCTGCGACCCGGGATCCTGAATTCCTGTGGCTGTCTCGGTATAGGTGCGC
AGAGCTGGAGCTGGAGATGCCAACGCCGCGCGGTTGTAACTCGGCCCTAGTTACCTGGCCAGGGTACGCGACAATTGGCGGAGGCAGGTA
TCCGTCCCGGAAGAAACGGTGGGGATTGGAGGAGGCCCGGCCACAGGGGGCGGGCTCCGTTCTGTTTTGGGGCGGAGCGATGGAGAAGAC
AGGCTTTCGATTGATGGAGCGGGCACACGGGGGCGGGTTCGTCTGGGGGCGGAGCGCGCGGGACGGGCGGCGGGATGAGGAGCTTGAGGA
AGCAGGCAGGGAAATGTCTGCCGCCGCCGGCTCTCGGGAGCGCAACACTGCAGGTGGTTCTAACTTTGATGGTTTGAGACCAAATGGGAA
GGGAGTGCCTATGGACCAAAGCTCCAGGGGTCAAGATAAACCAGAAAGCTTGCAACCAAGACAGAATAAATCCAAGTCCGAAATTACTGA
CATGGTTCGCTCCTCCACTATCACAGTGTCGGACAAGGCTCATATTTTATCCATGCAGAAGTTTGGACTGCGAGATACAATTGTGAAATC
ACATCTACTACAGAAAGAAGAGGATTACACCTATATCCAGAACTTCAGGTTTTTTGCGGGAACATACAATGTAAATGGGCAGTCCCCCAA
AGAATGCCTCCGGCTGTGGCTGAGCAATGGTATCCAGGCCCCAGATGTCTATTGTGTAGGGTTCCAGGAGCTTGATCTGAGTAAGGAAGC
TTTTTTCTTTCACGATACCCCAAAGGAGGAAGAGTGGTTCAAAGCTGTGTCAGAGGGTCTTCATCCAGATGCCAAATATGCAAAGGTGAA
GCTTATCCGACTGGTTGGGATTATGCTGCTGTTATATGTCAAACAGGAGCATGCAGCTTATATCTCAGAAGTGGAAGCCGAGACTGTGGG
GACAGGAATCATGGGGAGGATGGGCAACAAGGGAGGCGTGGCGATCAGGTTCCAGTTCCACAACACCAGCATCTGCGTTGTGAATTCTCA
CTTGGCAGCCCACATTGAAGAGTATGAGAGGAGGAACCAGGACTATAAGGACATTTGTTCTCGAATGCAGTTTTGTCAGCCTGACCCAAG
CCTTCCCCCTCTCACCATCAGCAACCATGACCAGGACTATCAACATGGTATCTTCCAATCAATTGGCTTCAAGGAATTTCACGAGTACCT
GATCACTGAGGGAAAATGCACACTGGAGACTAGTAACCAGCTTCTAAAGAAAGGTATTGAGGCTCTGAAACAAGTAACTAAGAGATATGC
CCGGAAACAAAACCGATGGGTTAAAAACCGTTTTTTGAGCAGACCTGGTCCCATTGTCCCCCCTGTCTATGGCTTAGAGGTATCTGATGT
CTCGAAGTGGGAAGAGTCTGTTCTTGAACCTGCTCTTGAAATCGTGCAAAGTTTCATCCAGGGCCACAAGCCTACAGCCACTCCAATAAA
GATGCCATACAATGAAGCTGAGAACAAGAGAAGTTATCACCTGTGTGACCTCTGTGATCGAATCATCATTGGGGATCGCGAATGGGCAGC
GCACATAAAATCCAAATCCCACTTGAACCAACTGAAGAAAAGAAGAAGATTGGACTCAGATGCTGTCAACACCATAGAAAGTCAGAGTGT
TTCCCCAGACCATAACAAAGAACCTAAAGAGAAGGGATCCCCAGGGCAGAATGATCAAGAGCTGAAATGCAGCGTTTAAGAGACATGTCC
AGTGGCCTTTGGAAAGGTGGTGGGGATCCAGTTCAGGAGGGAGGGGTATGTTTGTCTCCCAGTCTGGGCAAAGGAGTGCTATGCGGAATT
CTCTGCATAGCAGAAAAGCTCCCACCATTTTCTTTTGATGTGGTTTTAAAGTCTCACGTTCTCTATAATAGAAACAGCAGGTCTTGTCAG
CTCCTTGTGTGGCTGATGTGTCTGGAAATGATGTAGTTCAGGAAAGCATTTTTTTTTTCTTTGAACCTTAAAGGTTCTATTATTAAAAGC
AGCACAGATTCCACATTTTTATACATGAGGATCTTCTTTGTGGTGAATACCAGGATTGACTGCATCCCTTTAAAGAAGTTTTATGTCCCT
GACTCTGGCTAAAATTATCTAATTTCCAGATGCTTTTGTAGATGACTGAAGTATTTGTGAGCCACATATTGGGAGTTCTAGATTTGAGTG
AATGGCAGGAAAGGGCCATCTCCATTGAGATGATTAAGTGAACCAAACTAGTTCTCAGAATTCTACAGAGAAGGAGGGAATCAGACTGAG
GAAGCTGTGACATAGGACTTGAAGACCAAAGACTTTGAAATTTGCGAGCTGCTCATGTGTGAGTTATTATCACTGCTGTCTTTCTATTGA

>39825_39825_3_INPP5B-TRIT1_INPP5B_chr1_38351309_ENST00000373026_TRIT1_chr1_40313332_ENST00000441669_length(amino acids)=715AA_BP=520
MDQSVAIQETLAEGEYCVIAVQGVLCEGDSRQSRLLGLVRYRLEHGGQEHALFLYTHRRMAITGDDVSLDQIVPVSRDFTLEEVSPDGEL
YILGSDVTVQLDTAELSLVFQLPFGSQTRMFLHEVARACPGFDSATRDPEFLWLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGRY
PSRKKRWGLEEARPQGAGSVLFWGGAMEKTGFRLMERAHGGGFVWGRSARDGRRDEELEEAGREMSAAAGSRERNTAGGSNFDGLRPNGK
GVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPK
ECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVG
TGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDQDYQHGIFQSIGFKEFHEYL
ITEGKCTLETSNQLLKKGIEALKQVTKRYARKQNRWVKNRFLSRPGPIVPPVYGLEVSDVSKWEESVLEPALEIVQSFIQGHKPTATPIK

--------------------------------------------------------------
>39825_39825_4_INPP5B-TRIT1_INPP5B_chr1_38351309_ENST00000373027_TRIT1_chr1_40313332_ENST00000316891_length(transcript)=2146nt_BP=864nt
GCGGCGGGATGAGGAGCTTGAGGAAGCAGGCAGGGAAATGTCTGCCGCCGCCGGCTCTCGGGAGCGCAACACTGCAGGTGGTTCTAACTT
TGATGGTTTGAGACCAAATGGGAAGGGAGTGCCTATGGACCAAAGCTCCAGGGGTCAAGATAAACCAGAAAGCTTGCAACCAAGACAGAA
TAAATCCAAGTCCGAAATTACTGACATGGTTCGCTCCTCCACTATCACAGTGTCGGACAAGGCTCATATTTTATCCATGCAGAAGTTTGG
ACTGCGAGATACAATTGTGAAATCACATCTACTACAGAAAGAAGAGGATTACACCTATATCCAGAACTTCAGGTTTTTTGCGGGAACATA
CAATGTAAATGGGCAGTCCCCCAAAGAATGCCTCCGGCTGTGGCTGAGCAATGGTATCCAGGCCCCAGATGTCTATTGTGTAGGGTTCCA
GGAGCTTGATCTGAGTAAGGAAGCTTTTTTCTTTCACGATACCCCAAAGGAGGAAGAGTGGTTCAAAGCTGTGTCAGAGGGTCTTCATCC
AGATGCCAAATATGCAAAGGTGAAGCTTATCCGACTGGTTGGGATTATGCTGCTGTTATATGTCAAACAGGAGCATGCAGCTTATATCTC
AGAAGTGGAAGCCGAGACTGTGGGGACAGGAATCATGGGGAGGATGGGCAACAAGGGAGGCGTGGCGATCAGGTTCCAGTTCCACAACAC
CAGCATCTGCGTTGTGAATTCTCACTTGGCAGCCCACATTGAAGAGTATGAGAGGAGGAACCAGGACTATAAGGACATTTGTTCTCGAAT
GCAGTTTTGTCAGCCTGACCCAAGCCTTCCCCCTCTCACCATCAGCAACCATGACCAGGACTATCAACATGGTATCTTCCAATCAATTGG
CTTCAAGGAATTTCACGAGTACCTGATCACTGAGGGAAAATGCACACTGGAGACTAGTAACCAGCTTCTAAAGAAAGGTATTGAGGCTCT
GAAACAAGTAACTAAGAGATATGCCCGGAAACAAAACCGATGGGTTAAAAACCGTTTTTTGAGCAGACCTGGTCCCATTGTCCCCCCTGT
CTATGGCTTAGAGGTATCTGATGTCTCGAAGTGGGAAGAGTCTGTTCTTGAACCTGCTCTTGAAATCGTGCAAAGTTTCATCCAGGGCCA
CAAGCCTACAGCCACTCCAATAAAGATGCCATACAATGAAGCTGAGAACAAGAGAAGTTATCACCTGTGTGACCTCTGTGATCGAATCAT
CATTGGGGATCGCGAATGGGCAGCGCACATAAAATCCAAATCCCACTTGAACCAACTGAAGAAAAGAAGAAGATTGGACTCAGATGCTGT
CAACACCATAGAAAGTCAGAGTGTTTCCCCAGACCATAACAAAGAACCTAAAGAGAAGGGATCCCCAGGGCAGAATGATCAAGAGCTGAA
ATGCAGCGTTTAAGAGACATGTCCAGTGGCCTTTGGAAAGGTGGTGGGGATCCAGTTCAGGAGGGAGGGGTATGTTTGTCTCCCAGTCTG
GGCAAAGGAGTGCTATGCGGAATTCTCTGCATAGCAGAAAAGCTCCCACCATTTTCTTTTGATGTGGTTTTAAAGTCTCACGTTCTCTAT
AATAGAAACAGCAGGTCTTGTCAGCTCCTTGTGTGGCTGATGTGTCTGGAAATGATGTAGTTCAGGAAAGCATTTTTTTTTTCTTTGAAC
CTTAAAGGTTCTATTATTAAAAGCAGCACAGATTCCACATTTTTATACATGAGGATCTTCTTTGTGGTGAATACCAGGATTGACTGCATC
CCTTTAAAGAAGTTTTATGTCCCTGACTCTGGCTAAAATTATCTAATTTCCAGATGCTTTTGTAGATGACTGAAGTATTTGTGAGCCACA
TATTGGGAGTTCTAGATTTGAGTGAATGGCAGGAAAGGGCCATCTCCATTGAGATGATTAAGTGAACCAAACTAGTTCTCAGAATTCTAC
AGAGAAGGAGGGAATCAGACTGAGGAAGCTGTGACATAGGACTTGAAGACCAAAGACTTTGAAATTTGCGAGCTGCTCATGTGTGAGTTA

>39825_39825_4_INPP5B-TRIT1_INPP5B_chr1_38351309_ENST00000373027_TRIT1_chr1_40313332_ENST00000316891_length(amino acids)=471AA_BP=276
MSAAAGSRERNTAGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQ
KEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRL
VGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPL
TISNHDQDYQHGIFQSIGFKEFHEYLITEGKCTLETSNQLLKKGIEALKQVTKRYARKQNRWVKNRFLSRPGPIVPPVYGLEVSDVSKWE
ESVLEPALEIVQSFIQGHKPTATPIKMPYNEAENKRSYHLCDLCDRIIIGDREWAAHIKSKSHLNQLKKRRRLDSDAVNTIESQSVSPDH

--------------------------------------------------------------
>39825_39825_5_INPP5B-TRIT1_INPP5B_chr1_38351309_ENST00000373027_TRIT1_chr1_40313332_ENST00000372818_length(transcript)=2068nt_BP=864nt
GCGGCGGGATGAGGAGCTTGAGGAAGCAGGCAGGGAAATGTCTGCCGCCGCCGGCTCTCGGGAGCGCAACACTGCAGGTGGTTCTAACTT
TGATGGTTTGAGACCAAATGGGAAGGGAGTGCCTATGGACCAAAGCTCCAGGGGTCAAGATAAACCAGAAAGCTTGCAACCAAGACAGAA
TAAATCCAAGTCCGAAATTACTGACATGGTTCGCTCCTCCACTATCACAGTGTCGGACAAGGCTCATATTTTATCCATGCAGAAGTTTGG
ACTGCGAGATACAATTGTGAAATCACATCTACTACAGAAAGAAGAGGATTACACCTATATCCAGAACTTCAGGTTTTTTGCGGGAACATA
CAATGTAAATGGGCAGTCCCCCAAAGAATGCCTCCGGCTGTGGCTGAGCAATGGTATCCAGGCCCCAGATGTCTATTGTGTAGGGTTCCA
GGAGCTTGATCTGAGTAAGGAAGCTTTTTTCTTTCACGATACCCCAAAGGAGGAAGAGTGGTTCAAAGCTGTGTCAGAGGGTCTTCATCC
AGATGCCAAATATGCAAAGGTGAAGCTTATCCGACTGGTTGGGATTATGCTGCTGTTATATGTCAAACAGGAGCATGCAGCTTATATCTC
AGAAGTGGAAGCCGAGACTGTGGGGACAGGAATCATGGGGAGGATGGGCAACAAGGGAGGCGTGGCGATCAGGTTCCAGTTCCACAACAC
CAGCATCTGCGTTGTGAATTCTCACTTGGCAGCCCACATTGAAGAGTATGAGAGGAGGAACCAGGACTATAAGGACATTTGTTCTCGAAT
GCAGTTTTGTCAGCCTGACCCAAGCCTTCCCCCTCTCACCATCAGCAACCATGACCAGGACTATCAACATGGTATCTTCCAATCAATTGG
CTTCAAGGAATTTCACGAGTACCTGATCACTGAGGGAAAATGCACACTGGAGACTAGTAACCAGCTTCTAAAGAAAGGACCTGGTCCCAT
TGTCCCCCCTGTCTATGGCTTAGAGGTATCTGATGTCTCGAAGTGGGAAGAGTCTGTTCTTGAACCTGCTCTTGAAATCGTGCAAAGTTT
CATCCAGGGCCACAAGCCTACAGCCACTCCAATAAAGATGCCATACAATGAAGCTGAGAACAAGAGAAGTTATCACCTGTGTGACCTCTG
TGATCGAATCATCATTGGGGATCGCGAATGGGCAGCGCACATAAAATCCAAATCCCACTTGAACCAACTGAAGAAAAGAAGAAGATTGGA
CTCAGATGCTGTCAACACCATAGAAAGTCAGAGTGTTTCCCCAGACCATAACAAAGAACCTAAAGAGAAGGGATCCCCAGGGCAGAATGA
TCAAGAGCTGAAATGCAGCGTTTAAGAGACATGTCCAGTGGCCTTTGGAAAGGTGGTGGGGATCCAGTTCAGGAGGGAGGGGTATGTTTG
TCTCCCAGTCTGGGCAAAGGAGTGCTATGCGGAATTCTCTGCATAGCAGAAAAGCTCCCACCATTTTCTTTTGATGTGGTTTTAAAGTCT
CACGTTCTCTATAATAGAAACAGCAGGTCTTGTCAGCTCCTTGTGTGGCTGATGTGTCTGGAAATGATGTAGTTCAGGAAAGCATTTTTT
TTTTCTTTGAACCTTAAAGGTTCTATTATTAAAAGCAGCACAGATTCCACATTTTTATACATGAGGATCTTCTTTGTGGTGAATACCAGG
ATTGACTGCATCCCTTTAAAGAAGTTTTATGTCCCTGACTCTGGCTAAAATTATCTAATTTCCAGATGCTTTTGTAGATGACTGAAGTAT
TTGTGAGCCACATATTGGGAGTTCTAGATTTGAGTGAATGGCAGGAAAGGGCCATCTCCATTGAGATGATTAAGTGAACCAAACTAGTTC
TCAGAATTCTACAGAGAAGGAGGGAATCAGACTGAGGAAGCTGTGACATAGGACTTGAAGACCAAAGACTTTGAAATTTGCGAGCTGCTC

>39825_39825_5_INPP5B-TRIT1_INPP5B_chr1_38351309_ENST00000373027_TRIT1_chr1_40313332_ENST00000372818_length(amino acids)=445AA_BP=276
MSAAAGSRERNTAGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQ
KEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRL
VGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPL
TISNHDQDYQHGIFQSIGFKEFHEYLITEGKCTLETSNQLLKKGPGPIVPPVYGLEVSDVSKWEESVLEPALEIVQSFIQGHKPTATPIK

--------------------------------------------------------------
>39825_39825_6_INPP5B-TRIT1_INPP5B_chr1_38351309_ENST00000373027_TRIT1_chr1_40313332_ENST00000441669_length(transcript)=2146nt_BP=864nt
GCGGCGGGATGAGGAGCTTGAGGAAGCAGGCAGGGAAATGTCTGCCGCCGCCGGCTCTCGGGAGCGCAACACTGCAGGTGGTTCTAACTT
TGATGGTTTGAGACCAAATGGGAAGGGAGTGCCTATGGACCAAAGCTCCAGGGGTCAAGATAAACCAGAAAGCTTGCAACCAAGACAGAA
TAAATCCAAGTCCGAAATTACTGACATGGTTCGCTCCTCCACTATCACAGTGTCGGACAAGGCTCATATTTTATCCATGCAGAAGTTTGG
ACTGCGAGATACAATTGTGAAATCACATCTACTACAGAAAGAAGAGGATTACACCTATATCCAGAACTTCAGGTTTTTTGCGGGAACATA
CAATGTAAATGGGCAGTCCCCCAAAGAATGCCTCCGGCTGTGGCTGAGCAATGGTATCCAGGCCCCAGATGTCTATTGTGTAGGGTTCCA
GGAGCTTGATCTGAGTAAGGAAGCTTTTTTCTTTCACGATACCCCAAAGGAGGAAGAGTGGTTCAAAGCTGTGTCAGAGGGTCTTCATCC
AGATGCCAAATATGCAAAGGTGAAGCTTATCCGACTGGTTGGGATTATGCTGCTGTTATATGTCAAACAGGAGCATGCAGCTTATATCTC
AGAAGTGGAAGCCGAGACTGTGGGGACAGGAATCATGGGGAGGATGGGCAACAAGGGAGGCGTGGCGATCAGGTTCCAGTTCCACAACAC
CAGCATCTGCGTTGTGAATTCTCACTTGGCAGCCCACATTGAAGAGTATGAGAGGAGGAACCAGGACTATAAGGACATTTGTTCTCGAAT
GCAGTTTTGTCAGCCTGACCCAAGCCTTCCCCCTCTCACCATCAGCAACCATGACCAGGACTATCAACATGGTATCTTCCAATCAATTGG
CTTCAAGGAATTTCACGAGTACCTGATCACTGAGGGAAAATGCACACTGGAGACTAGTAACCAGCTTCTAAAGAAAGGTATTGAGGCTCT
GAAACAAGTAACTAAGAGATATGCCCGGAAACAAAACCGATGGGTTAAAAACCGTTTTTTGAGCAGACCTGGTCCCATTGTCCCCCCTGT
CTATGGCTTAGAGGTATCTGATGTCTCGAAGTGGGAAGAGTCTGTTCTTGAACCTGCTCTTGAAATCGTGCAAAGTTTCATCCAGGGCCA
CAAGCCTACAGCCACTCCAATAAAGATGCCATACAATGAAGCTGAGAACAAGAGAAGTTATCACCTGTGTGACCTCTGTGATCGAATCAT
CATTGGGGATCGCGAATGGGCAGCGCACATAAAATCCAAATCCCACTTGAACCAACTGAAGAAAAGAAGAAGATTGGACTCAGATGCTGT
CAACACCATAGAAAGTCAGAGTGTTTCCCCAGACCATAACAAAGAACCTAAAGAGAAGGGATCCCCAGGGCAGAATGATCAAGAGCTGAA
ATGCAGCGTTTAAGAGACATGTCCAGTGGCCTTTGGAAAGGTGGTGGGGATCCAGTTCAGGAGGGAGGGGTATGTTTGTCTCCCAGTCTG
GGCAAAGGAGTGCTATGCGGAATTCTCTGCATAGCAGAAAAGCTCCCACCATTTTCTTTTGATGTGGTTTTAAAGTCTCACGTTCTCTAT
AATAGAAACAGCAGGTCTTGTCAGCTCCTTGTGTGGCTGATGTGTCTGGAAATGATGTAGTTCAGGAAAGCATTTTTTTTTTCTTTGAAC
CTTAAAGGTTCTATTATTAAAAGCAGCACAGATTCCACATTTTTATACATGAGGATCTTCTTTGTGGTGAATACCAGGATTGACTGCATC
CCTTTAAAGAAGTTTTATGTCCCTGACTCTGGCTAAAATTATCTAATTTCCAGATGCTTTTGTAGATGACTGAAGTATTTGTGAGCCACA
TATTGGGAGTTCTAGATTTGAGTGAATGGCAGGAAAGGGCCATCTCCATTGAGATGATTAAGTGAACCAAACTAGTTCTCAGAATTCTAC
AGAGAAGGAGGGAATCAGACTGAGGAAGCTGTGACATAGGACTTGAAGACCAAAGACTTTGAAATTTGCGAGCTGCTCATGTGTGAGTTA

>39825_39825_6_INPP5B-TRIT1_INPP5B_chr1_38351309_ENST00000373027_TRIT1_chr1_40313332_ENST00000441669_length(amino acids)=471AA_BP=276
MSAAAGSRERNTAGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQ
KEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRL
VGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPL
TISNHDQDYQHGIFQSIGFKEFHEYLITEGKCTLETSNQLLKKGIEALKQVTKRYARKQNRWVKNRFLSRPGPIVPPVYGLEVSDVSKWE
ESVLEPALEIVQSFIQGHKPTATPIKMPYNEAENKRSYHLCDLCDRIIIGDREWAAHIKSKSHLNQLKKRRRLDSDAVNTIESQSVSPDH

--------------------------------------------------------------
>39825_39825_7_INPP5B-TRIT1_INPP5B_chr1_38351310_ENST00000373026_TRIT1_chr1_40313332_ENST00000316891_length(transcript)=2842nt_BP=1560nt
CATGGACCAGTCTGTGGCAATCCAGGAGACGCTGGCTGAGGGGGAATACTGCGTCATCGCGGTGCAAGGTGTGCTGTGTGAGGGGGACAG
CCGGCAGAGCCGCCTCCTGGGACTCGTGCGCTACCGCCTGGAGCACGGCGGCCAGGAACACGCTCTCTTCCTCTATACGCACCGGAGGAT
GGCCATTACCGGGGACGATGTCTCTCTGGACCAGATAGTGCCAGTCTCGCGGGATTTTACGCTGGAAGAAGTGTCCCCAGATGGTGAACT
CTACATCCTTGGCTCAGATGTGACCGTCCAGCTGGACACAGCAGAGCTTAGCCTCGTATTCCAACTGCCCTTTGGTTCACAAACCAGGAT
GTTCCTCCACGAAGTTGCCAGGGCCTGTCCAGGCTTCGATTCTGCGACCCGGGATCCTGAATTCCTGTGGCTGTCTCGGTATAGGTGCGC
AGAGCTGGAGCTGGAGATGCCAACGCCGCGCGGTTGTAACTCGGCCCTAGTTACCTGGCCAGGGTACGCGACAATTGGCGGAGGCAGGTA
TCCGTCCCGGAAGAAACGGTGGGGATTGGAGGAGGCCCGGCCACAGGGGGCGGGCTCCGTTCTGTTTTGGGGCGGAGCGATGGAGAAGAC
AGGCTTTCGATTGATGGAGCGGGCACACGGGGGCGGGTTCGTCTGGGGGCGGAGCGCGCGGGACGGGCGGCGGGATGAGGAGCTTGAGGA
AGCAGGCAGGGAAATGTCTGCCGCCGCCGGCTCTCGGGAGCGCAACACTGCAGGTGGTTCTAACTTTGATGGTTTGAGACCAAATGGGAA
GGGAGTGCCTATGGACCAAAGCTCCAGGGGTCAAGATAAACCAGAAAGCTTGCAACCAAGACAGAATAAATCCAAGTCCGAAATTACTGA
CATGGTTCGCTCCTCCACTATCACAGTGTCGGACAAGGCTCATATTTTATCCATGCAGAAGTTTGGACTGCGAGATACAATTGTGAAATC
ACATCTACTACAGAAAGAAGAGGATTACACCTATATCCAGAACTTCAGGTTTTTTGCGGGAACATACAATGTAAATGGGCAGTCCCCCAA
AGAATGCCTCCGGCTGTGGCTGAGCAATGGTATCCAGGCCCCAGATGTCTATTGTGTAGGGTTCCAGGAGCTTGATCTGAGTAAGGAAGC
TTTTTTCTTTCACGATACCCCAAAGGAGGAAGAGTGGTTCAAAGCTGTGTCAGAGGGTCTTCATCCAGATGCCAAATATGCAAAGGTGAA
GCTTATCCGACTGGTTGGGATTATGCTGCTGTTATATGTCAAACAGGAGCATGCAGCTTATATCTCAGAAGTGGAAGCCGAGACTGTGGG
GACAGGAATCATGGGGAGGATGGGCAACAAGGGAGGCGTGGCGATCAGGTTCCAGTTCCACAACACCAGCATCTGCGTTGTGAATTCTCA
CTTGGCAGCCCACATTGAAGAGTATGAGAGGAGGAACCAGGACTATAAGGACATTTGTTCTCGAATGCAGTTTTGTCAGCCTGACCCAAG
CCTTCCCCCTCTCACCATCAGCAACCATGACCAGGACTATCAACATGGTATCTTCCAATCAATTGGCTTCAAGGAATTTCACGAGTACCT
GATCACTGAGGGAAAATGCACACTGGAGACTAGTAACCAGCTTCTAAAGAAAGGTATTGAGGCTCTGAAACAAGTAACTAAGAGATATGC
CCGGAAACAAAACCGATGGGTTAAAAACCGTTTTTTGAGCAGACCTGGTCCCATTGTCCCCCCTGTCTATGGCTTAGAGGTATCTGATGT
CTCGAAGTGGGAAGAGTCTGTTCTTGAACCTGCTCTTGAAATCGTGCAAAGTTTCATCCAGGGCCACAAGCCTACAGCCACTCCAATAAA
GATGCCATACAATGAAGCTGAGAACAAGAGAAGTTATCACCTGTGTGACCTCTGTGATCGAATCATCATTGGGGATCGCGAATGGGCAGC
GCACATAAAATCCAAATCCCACTTGAACCAACTGAAGAAAAGAAGAAGATTGGACTCAGATGCTGTCAACACCATAGAAAGTCAGAGTGT
TTCCCCAGACCATAACAAAGAACCTAAAGAGAAGGGATCCCCAGGGCAGAATGATCAAGAGCTGAAATGCAGCGTTTAAGAGACATGTCC
AGTGGCCTTTGGAAAGGTGGTGGGGATCCAGTTCAGGAGGGAGGGGTATGTTTGTCTCCCAGTCTGGGCAAAGGAGTGCTATGCGGAATT
CTCTGCATAGCAGAAAAGCTCCCACCATTTTCTTTTGATGTGGTTTTAAAGTCTCACGTTCTCTATAATAGAAACAGCAGGTCTTGTCAG
CTCCTTGTGTGGCTGATGTGTCTGGAAATGATGTAGTTCAGGAAAGCATTTTTTTTTTCTTTGAACCTTAAAGGTTCTATTATTAAAAGC
AGCACAGATTCCACATTTTTATACATGAGGATCTTCTTTGTGGTGAATACCAGGATTGACTGCATCCCTTTAAAGAAGTTTTATGTCCCT
GACTCTGGCTAAAATTATCTAATTTCCAGATGCTTTTGTAGATGACTGAAGTATTTGTGAGCCACATATTGGGAGTTCTAGATTTGAGTG
AATGGCAGGAAAGGGCCATCTCCATTGAGATGATTAAGTGAACCAAACTAGTTCTCAGAATTCTACAGAGAAGGAGGGAATCAGACTGAG
GAAGCTGTGACATAGGACTTGAAGACCAAAGACTTTGAAATTTGCGAGCTGCTCATGTGTGAGTTATTATCACTGCTGTCTTTCTATTGA

>39825_39825_7_INPP5B-TRIT1_INPP5B_chr1_38351310_ENST00000373026_TRIT1_chr1_40313332_ENST00000316891_length(amino acids)=715AA_BP=520
MDQSVAIQETLAEGEYCVIAVQGVLCEGDSRQSRLLGLVRYRLEHGGQEHALFLYTHRRMAITGDDVSLDQIVPVSRDFTLEEVSPDGEL
YILGSDVTVQLDTAELSLVFQLPFGSQTRMFLHEVARACPGFDSATRDPEFLWLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGRY
PSRKKRWGLEEARPQGAGSVLFWGGAMEKTGFRLMERAHGGGFVWGRSARDGRRDEELEEAGREMSAAAGSRERNTAGGSNFDGLRPNGK
GVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPK
ECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVG
TGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDQDYQHGIFQSIGFKEFHEYL
ITEGKCTLETSNQLLKKGIEALKQVTKRYARKQNRWVKNRFLSRPGPIVPPVYGLEVSDVSKWEESVLEPALEIVQSFIQGHKPTATPIK

--------------------------------------------------------------
>39825_39825_8_INPP5B-TRIT1_INPP5B_chr1_38351310_ENST00000373026_TRIT1_chr1_40313332_ENST00000372818_length(transcript)=2764nt_BP=1560nt
CATGGACCAGTCTGTGGCAATCCAGGAGACGCTGGCTGAGGGGGAATACTGCGTCATCGCGGTGCAAGGTGTGCTGTGTGAGGGGGACAG
CCGGCAGAGCCGCCTCCTGGGACTCGTGCGCTACCGCCTGGAGCACGGCGGCCAGGAACACGCTCTCTTCCTCTATACGCACCGGAGGAT
GGCCATTACCGGGGACGATGTCTCTCTGGACCAGATAGTGCCAGTCTCGCGGGATTTTACGCTGGAAGAAGTGTCCCCAGATGGTGAACT
CTACATCCTTGGCTCAGATGTGACCGTCCAGCTGGACACAGCAGAGCTTAGCCTCGTATTCCAACTGCCCTTTGGTTCACAAACCAGGAT
GTTCCTCCACGAAGTTGCCAGGGCCTGTCCAGGCTTCGATTCTGCGACCCGGGATCCTGAATTCCTGTGGCTGTCTCGGTATAGGTGCGC
AGAGCTGGAGCTGGAGATGCCAACGCCGCGCGGTTGTAACTCGGCCCTAGTTACCTGGCCAGGGTACGCGACAATTGGCGGAGGCAGGTA
TCCGTCCCGGAAGAAACGGTGGGGATTGGAGGAGGCCCGGCCACAGGGGGCGGGCTCCGTTCTGTTTTGGGGCGGAGCGATGGAGAAGAC
AGGCTTTCGATTGATGGAGCGGGCACACGGGGGCGGGTTCGTCTGGGGGCGGAGCGCGCGGGACGGGCGGCGGGATGAGGAGCTTGAGGA
AGCAGGCAGGGAAATGTCTGCCGCCGCCGGCTCTCGGGAGCGCAACACTGCAGGTGGTTCTAACTTTGATGGTTTGAGACCAAATGGGAA
GGGAGTGCCTATGGACCAAAGCTCCAGGGGTCAAGATAAACCAGAAAGCTTGCAACCAAGACAGAATAAATCCAAGTCCGAAATTACTGA
CATGGTTCGCTCCTCCACTATCACAGTGTCGGACAAGGCTCATATTTTATCCATGCAGAAGTTTGGACTGCGAGATACAATTGTGAAATC
ACATCTACTACAGAAAGAAGAGGATTACACCTATATCCAGAACTTCAGGTTTTTTGCGGGAACATACAATGTAAATGGGCAGTCCCCCAA
AGAATGCCTCCGGCTGTGGCTGAGCAATGGTATCCAGGCCCCAGATGTCTATTGTGTAGGGTTCCAGGAGCTTGATCTGAGTAAGGAAGC
TTTTTTCTTTCACGATACCCCAAAGGAGGAAGAGTGGTTCAAAGCTGTGTCAGAGGGTCTTCATCCAGATGCCAAATATGCAAAGGTGAA
GCTTATCCGACTGGTTGGGATTATGCTGCTGTTATATGTCAAACAGGAGCATGCAGCTTATATCTCAGAAGTGGAAGCCGAGACTGTGGG
GACAGGAATCATGGGGAGGATGGGCAACAAGGGAGGCGTGGCGATCAGGTTCCAGTTCCACAACACCAGCATCTGCGTTGTGAATTCTCA
CTTGGCAGCCCACATTGAAGAGTATGAGAGGAGGAACCAGGACTATAAGGACATTTGTTCTCGAATGCAGTTTTGTCAGCCTGACCCAAG
CCTTCCCCCTCTCACCATCAGCAACCATGACCAGGACTATCAACATGGTATCTTCCAATCAATTGGCTTCAAGGAATTTCACGAGTACCT
GATCACTGAGGGAAAATGCACACTGGAGACTAGTAACCAGCTTCTAAAGAAAGGACCTGGTCCCATTGTCCCCCCTGTCTATGGCTTAGA
GGTATCTGATGTCTCGAAGTGGGAAGAGTCTGTTCTTGAACCTGCTCTTGAAATCGTGCAAAGTTTCATCCAGGGCCACAAGCCTACAGC
CACTCCAATAAAGATGCCATACAATGAAGCTGAGAACAAGAGAAGTTATCACCTGTGTGACCTCTGTGATCGAATCATCATTGGGGATCG
CGAATGGGCAGCGCACATAAAATCCAAATCCCACTTGAACCAACTGAAGAAAAGAAGAAGATTGGACTCAGATGCTGTCAACACCATAGA
AAGTCAGAGTGTTTCCCCAGACCATAACAAAGAACCTAAAGAGAAGGGATCCCCAGGGCAGAATGATCAAGAGCTGAAATGCAGCGTTTA
AGAGACATGTCCAGTGGCCTTTGGAAAGGTGGTGGGGATCCAGTTCAGGAGGGAGGGGTATGTTTGTCTCCCAGTCTGGGCAAAGGAGTG
CTATGCGGAATTCTCTGCATAGCAGAAAAGCTCCCACCATTTTCTTTTGATGTGGTTTTAAAGTCTCACGTTCTCTATAATAGAAACAGC
AGGTCTTGTCAGCTCCTTGTGTGGCTGATGTGTCTGGAAATGATGTAGTTCAGGAAAGCATTTTTTTTTTCTTTGAACCTTAAAGGTTCT
ATTATTAAAAGCAGCACAGATTCCACATTTTTATACATGAGGATCTTCTTTGTGGTGAATACCAGGATTGACTGCATCCCTTTAAAGAAG
TTTTATGTCCCTGACTCTGGCTAAAATTATCTAATTTCCAGATGCTTTTGTAGATGACTGAAGTATTTGTGAGCCACATATTGGGAGTTC
TAGATTTGAGTGAATGGCAGGAAAGGGCCATCTCCATTGAGATGATTAAGTGAACCAAACTAGTTCTCAGAATTCTACAGAGAAGGAGGG
AATCAGACTGAGGAAGCTGTGACATAGGACTTGAAGACCAAAGACTTTGAAATTTGCGAGCTGCTCATGTGTGAGTTATTATCACTGCTG

>39825_39825_8_INPP5B-TRIT1_INPP5B_chr1_38351310_ENST00000373026_TRIT1_chr1_40313332_ENST00000372818_length(amino acids)=689AA_BP=520
MDQSVAIQETLAEGEYCVIAVQGVLCEGDSRQSRLLGLVRYRLEHGGQEHALFLYTHRRMAITGDDVSLDQIVPVSRDFTLEEVSPDGEL
YILGSDVTVQLDTAELSLVFQLPFGSQTRMFLHEVARACPGFDSATRDPEFLWLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGRY
PSRKKRWGLEEARPQGAGSVLFWGGAMEKTGFRLMERAHGGGFVWGRSARDGRRDEELEEAGREMSAAAGSRERNTAGGSNFDGLRPNGK
GVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPK
ECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVG
TGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDQDYQHGIFQSIGFKEFHEYL
ITEGKCTLETSNQLLKKGPGPIVPPVYGLEVSDVSKWEESVLEPALEIVQSFIQGHKPTATPIKMPYNEAENKRSYHLCDLCDRIIIGDR

--------------------------------------------------------------
>39825_39825_9_INPP5B-TRIT1_INPP5B_chr1_38351310_ENST00000373026_TRIT1_chr1_40313332_ENST00000441669_length(transcript)=2842nt_BP=1560nt
CATGGACCAGTCTGTGGCAATCCAGGAGACGCTGGCTGAGGGGGAATACTGCGTCATCGCGGTGCAAGGTGTGCTGTGTGAGGGGGACAG
CCGGCAGAGCCGCCTCCTGGGACTCGTGCGCTACCGCCTGGAGCACGGCGGCCAGGAACACGCTCTCTTCCTCTATACGCACCGGAGGAT
GGCCATTACCGGGGACGATGTCTCTCTGGACCAGATAGTGCCAGTCTCGCGGGATTTTACGCTGGAAGAAGTGTCCCCAGATGGTGAACT
CTACATCCTTGGCTCAGATGTGACCGTCCAGCTGGACACAGCAGAGCTTAGCCTCGTATTCCAACTGCCCTTTGGTTCACAAACCAGGAT
GTTCCTCCACGAAGTTGCCAGGGCCTGTCCAGGCTTCGATTCTGCGACCCGGGATCCTGAATTCCTGTGGCTGTCTCGGTATAGGTGCGC
AGAGCTGGAGCTGGAGATGCCAACGCCGCGCGGTTGTAACTCGGCCCTAGTTACCTGGCCAGGGTACGCGACAATTGGCGGAGGCAGGTA
TCCGTCCCGGAAGAAACGGTGGGGATTGGAGGAGGCCCGGCCACAGGGGGCGGGCTCCGTTCTGTTTTGGGGCGGAGCGATGGAGAAGAC
AGGCTTTCGATTGATGGAGCGGGCACACGGGGGCGGGTTCGTCTGGGGGCGGAGCGCGCGGGACGGGCGGCGGGATGAGGAGCTTGAGGA
AGCAGGCAGGGAAATGTCTGCCGCCGCCGGCTCTCGGGAGCGCAACACTGCAGGTGGTTCTAACTTTGATGGTTTGAGACCAAATGGGAA
GGGAGTGCCTATGGACCAAAGCTCCAGGGGTCAAGATAAACCAGAAAGCTTGCAACCAAGACAGAATAAATCCAAGTCCGAAATTACTGA
CATGGTTCGCTCCTCCACTATCACAGTGTCGGACAAGGCTCATATTTTATCCATGCAGAAGTTTGGACTGCGAGATACAATTGTGAAATC
ACATCTACTACAGAAAGAAGAGGATTACACCTATATCCAGAACTTCAGGTTTTTTGCGGGAACATACAATGTAAATGGGCAGTCCCCCAA
AGAATGCCTCCGGCTGTGGCTGAGCAATGGTATCCAGGCCCCAGATGTCTATTGTGTAGGGTTCCAGGAGCTTGATCTGAGTAAGGAAGC
TTTTTTCTTTCACGATACCCCAAAGGAGGAAGAGTGGTTCAAAGCTGTGTCAGAGGGTCTTCATCCAGATGCCAAATATGCAAAGGTGAA
GCTTATCCGACTGGTTGGGATTATGCTGCTGTTATATGTCAAACAGGAGCATGCAGCTTATATCTCAGAAGTGGAAGCCGAGACTGTGGG
GACAGGAATCATGGGGAGGATGGGCAACAAGGGAGGCGTGGCGATCAGGTTCCAGTTCCACAACACCAGCATCTGCGTTGTGAATTCTCA
CTTGGCAGCCCACATTGAAGAGTATGAGAGGAGGAACCAGGACTATAAGGACATTTGTTCTCGAATGCAGTTTTGTCAGCCTGACCCAAG
CCTTCCCCCTCTCACCATCAGCAACCATGACCAGGACTATCAACATGGTATCTTCCAATCAATTGGCTTCAAGGAATTTCACGAGTACCT
GATCACTGAGGGAAAATGCACACTGGAGACTAGTAACCAGCTTCTAAAGAAAGGTATTGAGGCTCTGAAACAAGTAACTAAGAGATATGC
CCGGAAACAAAACCGATGGGTTAAAAACCGTTTTTTGAGCAGACCTGGTCCCATTGTCCCCCCTGTCTATGGCTTAGAGGTATCTGATGT
CTCGAAGTGGGAAGAGTCTGTTCTTGAACCTGCTCTTGAAATCGTGCAAAGTTTCATCCAGGGCCACAAGCCTACAGCCACTCCAATAAA
GATGCCATACAATGAAGCTGAGAACAAGAGAAGTTATCACCTGTGTGACCTCTGTGATCGAATCATCATTGGGGATCGCGAATGGGCAGC
GCACATAAAATCCAAATCCCACTTGAACCAACTGAAGAAAAGAAGAAGATTGGACTCAGATGCTGTCAACACCATAGAAAGTCAGAGTGT
TTCCCCAGACCATAACAAAGAACCTAAAGAGAAGGGATCCCCAGGGCAGAATGATCAAGAGCTGAAATGCAGCGTTTAAGAGACATGTCC
AGTGGCCTTTGGAAAGGTGGTGGGGATCCAGTTCAGGAGGGAGGGGTATGTTTGTCTCCCAGTCTGGGCAAAGGAGTGCTATGCGGAATT
CTCTGCATAGCAGAAAAGCTCCCACCATTTTCTTTTGATGTGGTTTTAAAGTCTCACGTTCTCTATAATAGAAACAGCAGGTCTTGTCAG
CTCCTTGTGTGGCTGATGTGTCTGGAAATGATGTAGTTCAGGAAAGCATTTTTTTTTTCTTTGAACCTTAAAGGTTCTATTATTAAAAGC
AGCACAGATTCCACATTTTTATACATGAGGATCTTCTTTGTGGTGAATACCAGGATTGACTGCATCCCTTTAAAGAAGTTTTATGTCCCT
GACTCTGGCTAAAATTATCTAATTTCCAGATGCTTTTGTAGATGACTGAAGTATTTGTGAGCCACATATTGGGAGTTCTAGATTTGAGTG
AATGGCAGGAAAGGGCCATCTCCATTGAGATGATTAAGTGAACCAAACTAGTTCTCAGAATTCTACAGAGAAGGAGGGAATCAGACTGAG
GAAGCTGTGACATAGGACTTGAAGACCAAAGACTTTGAAATTTGCGAGCTGCTCATGTGTGAGTTATTATCACTGCTGTCTTTCTATTGA

>39825_39825_9_INPP5B-TRIT1_INPP5B_chr1_38351310_ENST00000373026_TRIT1_chr1_40313332_ENST00000441669_length(amino acids)=715AA_BP=520
MDQSVAIQETLAEGEYCVIAVQGVLCEGDSRQSRLLGLVRYRLEHGGQEHALFLYTHRRMAITGDDVSLDQIVPVSRDFTLEEVSPDGEL
YILGSDVTVQLDTAELSLVFQLPFGSQTRMFLHEVARACPGFDSATRDPEFLWLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGRY
PSRKKRWGLEEARPQGAGSVLFWGGAMEKTGFRLMERAHGGGFVWGRSARDGRRDEELEEAGREMSAAAGSRERNTAGGSNFDGLRPNGK
GVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPK
ECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVG
TGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDQDYQHGIFQSIGFKEFHEYL
ITEGKCTLETSNQLLKKGIEALKQVTKRYARKQNRWVKNRFLSRPGPIVPPVYGLEVSDVSKWEESVLEPALEIVQSFIQGHKPTATPIK

--------------------------------------------------------------
>39825_39825_10_INPP5B-TRIT1_INPP5B_chr1_38351310_ENST00000373027_TRIT1_chr1_40313332_ENST00000316891_length(transcript)=2146nt_BP=864nt
GCGGCGGGATGAGGAGCTTGAGGAAGCAGGCAGGGAAATGTCTGCCGCCGCCGGCTCTCGGGAGCGCAACACTGCAGGTGGTTCTAACTT
TGATGGTTTGAGACCAAATGGGAAGGGAGTGCCTATGGACCAAAGCTCCAGGGGTCAAGATAAACCAGAAAGCTTGCAACCAAGACAGAA
TAAATCCAAGTCCGAAATTACTGACATGGTTCGCTCCTCCACTATCACAGTGTCGGACAAGGCTCATATTTTATCCATGCAGAAGTTTGG
ACTGCGAGATACAATTGTGAAATCACATCTACTACAGAAAGAAGAGGATTACACCTATATCCAGAACTTCAGGTTTTTTGCGGGAACATA
CAATGTAAATGGGCAGTCCCCCAAAGAATGCCTCCGGCTGTGGCTGAGCAATGGTATCCAGGCCCCAGATGTCTATTGTGTAGGGTTCCA
GGAGCTTGATCTGAGTAAGGAAGCTTTTTTCTTTCACGATACCCCAAAGGAGGAAGAGTGGTTCAAAGCTGTGTCAGAGGGTCTTCATCC
AGATGCCAAATATGCAAAGGTGAAGCTTATCCGACTGGTTGGGATTATGCTGCTGTTATATGTCAAACAGGAGCATGCAGCTTATATCTC
AGAAGTGGAAGCCGAGACTGTGGGGACAGGAATCATGGGGAGGATGGGCAACAAGGGAGGCGTGGCGATCAGGTTCCAGTTCCACAACAC
CAGCATCTGCGTTGTGAATTCTCACTTGGCAGCCCACATTGAAGAGTATGAGAGGAGGAACCAGGACTATAAGGACATTTGTTCTCGAAT
GCAGTTTTGTCAGCCTGACCCAAGCCTTCCCCCTCTCACCATCAGCAACCATGACCAGGACTATCAACATGGTATCTTCCAATCAATTGG
CTTCAAGGAATTTCACGAGTACCTGATCACTGAGGGAAAATGCACACTGGAGACTAGTAACCAGCTTCTAAAGAAAGGTATTGAGGCTCT
GAAACAAGTAACTAAGAGATATGCCCGGAAACAAAACCGATGGGTTAAAAACCGTTTTTTGAGCAGACCTGGTCCCATTGTCCCCCCTGT
CTATGGCTTAGAGGTATCTGATGTCTCGAAGTGGGAAGAGTCTGTTCTTGAACCTGCTCTTGAAATCGTGCAAAGTTTCATCCAGGGCCA
CAAGCCTACAGCCACTCCAATAAAGATGCCATACAATGAAGCTGAGAACAAGAGAAGTTATCACCTGTGTGACCTCTGTGATCGAATCAT
CATTGGGGATCGCGAATGGGCAGCGCACATAAAATCCAAATCCCACTTGAACCAACTGAAGAAAAGAAGAAGATTGGACTCAGATGCTGT
CAACACCATAGAAAGTCAGAGTGTTTCCCCAGACCATAACAAAGAACCTAAAGAGAAGGGATCCCCAGGGCAGAATGATCAAGAGCTGAA
ATGCAGCGTTTAAGAGACATGTCCAGTGGCCTTTGGAAAGGTGGTGGGGATCCAGTTCAGGAGGGAGGGGTATGTTTGTCTCCCAGTCTG
GGCAAAGGAGTGCTATGCGGAATTCTCTGCATAGCAGAAAAGCTCCCACCATTTTCTTTTGATGTGGTTTTAAAGTCTCACGTTCTCTAT
AATAGAAACAGCAGGTCTTGTCAGCTCCTTGTGTGGCTGATGTGTCTGGAAATGATGTAGTTCAGGAAAGCATTTTTTTTTTCTTTGAAC
CTTAAAGGTTCTATTATTAAAAGCAGCACAGATTCCACATTTTTATACATGAGGATCTTCTTTGTGGTGAATACCAGGATTGACTGCATC
CCTTTAAAGAAGTTTTATGTCCCTGACTCTGGCTAAAATTATCTAATTTCCAGATGCTTTTGTAGATGACTGAAGTATTTGTGAGCCACA
TATTGGGAGTTCTAGATTTGAGTGAATGGCAGGAAAGGGCCATCTCCATTGAGATGATTAAGTGAACCAAACTAGTTCTCAGAATTCTAC
AGAGAAGGAGGGAATCAGACTGAGGAAGCTGTGACATAGGACTTGAAGACCAAAGACTTTGAAATTTGCGAGCTGCTCATGTGTGAGTTA

>39825_39825_10_INPP5B-TRIT1_INPP5B_chr1_38351310_ENST00000373027_TRIT1_chr1_40313332_ENST00000316891_length(amino acids)=471AA_BP=276
MSAAAGSRERNTAGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQ
KEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRL
VGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPL
TISNHDQDYQHGIFQSIGFKEFHEYLITEGKCTLETSNQLLKKGIEALKQVTKRYARKQNRWVKNRFLSRPGPIVPPVYGLEVSDVSKWE
ESVLEPALEIVQSFIQGHKPTATPIKMPYNEAENKRSYHLCDLCDRIIIGDREWAAHIKSKSHLNQLKKRRRLDSDAVNTIESQSVSPDH

--------------------------------------------------------------
>39825_39825_11_INPP5B-TRIT1_INPP5B_chr1_38351310_ENST00000373027_TRIT1_chr1_40313332_ENST00000372818_length(transcript)=2068nt_BP=864nt
GCGGCGGGATGAGGAGCTTGAGGAAGCAGGCAGGGAAATGTCTGCCGCCGCCGGCTCTCGGGAGCGCAACACTGCAGGTGGTTCTAACTT
TGATGGTTTGAGACCAAATGGGAAGGGAGTGCCTATGGACCAAAGCTCCAGGGGTCAAGATAAACCAGAAAGCTTGCAACCAAGACAGAA
TAAATCCAAGTCCGAAATTACTGACATGGTTCGCTCCTCCACTATCACAGTGTCGGACAAGGCTCATATTTTATCCATGCAGAAGTTTGG
ACTGCGAGATACAATTGTGAAATCACATCTACTACAGAAAGAAGAGGATTACACCTATATCCAGAACTTCAGGTTTTTTGCGGGAACATA
CAATGTAAATGGGCAGTCCCCCAAAGAATGCCTCCGGCTGTGGCTGAGCAATGGTATCCAGGCCCCAGATGTCTATTGTGTAGGGTTCCA
GGAGCTTGATCTGAGTAAGGAAGCTTTTTTCTTTCACGATACCCCAAAGGAGGAAGAGTGGTTCAAAGCTGTGTCAGAGGGTCTTCATCC
AGATGCCAAATATGCAAAGGTGAAGCTTATCCGACTGGTTGGGATTATGCTGCTGTTATATGTCAAACAGGAGCATGCAGCTTATATCTC
AGAAGTGGAAGCCGAGACTGTGGGGACAGGAATCATGGGGAGGATGGGCAACAAGGGAGGCGTGGCGATCAGGTTCCAGTTCCACAACAC
CAGCATCTGCGTTGTGAATTCTCACTTGGCAGCCCACATTGAAGAGTATGAGAGGAGGAACCAGGACTATAAGGACATTTGTTCTCGAAT
GCAGTTTTGTCAGCCTGACCCAAGCCTTCCCCCTCTCACCATCAGCAACCATGACCAGGACTATCAACATGGTATCTTCCAATCAATTGG
CTTCAAGGAATTTCACGAGTACCTGATCACTGAGGGAAAATGCACACTGGAGACTAGTAACCAGCTTCTAAAGAAAGGACCTGGTCCCAT
TGTCCCCCCTGTCTATGGCTTAGAGGTATCTGATGTCTCGAAGTGGGAAGAGTCTGTTCTTGAACCTGCTCTTGAAATCGTGCAAAGTTT
CATCCAGGGCCACAAGCCTACAGCCACTCCAATAAAGATGCCATACAATGAAGCTGAGAACAAGAGAAGTTATCACCTGTGTGACCTCTG
TGATCGAATCATCATTGGGGATCGCGAATGGGCAGCGCACATAAAATCCAAATCCCACTTGAACCAACTGAAGAAAAGAAGAAGATTGGA
CTCAGATGCTGTCAACACCATAGAAAGTCAGAGTGTTTCCCCAGACCATAACAAAGAACCTAAAGAGAAGGGATCCCCAGGGCAGAATGA
TCAAGAGCTGAAATGCAGCGTTTAAGAGACATGTCCAGTGGCCTTTGGAAAGGTGGTGGGGATCCAGTTCAGGAGGGAGGGGTATGTTTG
TCTCCCAGTCTGGGCAAAGGAGTGCTATGCGGAATTCTCTGCATAGCAGAAAAGCTCCCACCATTTTCTTTTGATGTGGTTTTAAAGTCT
CACGTTCTCTATAATAGAAACAGCAGGTCTTGTCAGCTCCTTGTGTGGCTGATGTGTCTGGAAATGATGTAGTTCAGGAAAGCATTTTTT
TTTTCTTTGAACCTTAAAGGTTCTATTATTAAAAGCAGCACAGATTCCACATTTTTATACATGAGGATCTTCTTTGTGGTGAATACCAGG
ATTGACTGCATCCCTTTAAAGAAGTTTTATGTCCCTGACTCTGGCTAAAATTATCTAATTTCCAGATGCTTTTGTAGATGACTGAAGTAT
TTGTGAGCCACATATTGGGAGTTCTAGATTTGAGTGAATGGCAGGAAAGGGCCATCTCCATTGAGATGATTAAGTGAACCAAACTAGTTC
TCAGAATTCTACAGAGAAGGAGGGAATCAGACTGAGGAAGCTGTGACATAGGACTTGAAGACCAAAGACTTTGAAATTTGCGAGCTGCTC

>39825_39825_11_INPP5B-TRIT1_INPP5B_chr1_38351310_ENST00000373027_TRIT1_chr1_40313332_ENST00000372818_length(amino acids)=445AA_BP=276
MSAAAGSRERNTAGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQ
KEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRL
VGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPL
TISNHDQDYQHGIFQSIGFKEFHEYLITEGKCTLETSNQLLKKGPGPIVPPVYGLEVSDVSKWEESVLEPALEIVQSFIQGHKPTATPIK

--------------------------------------------------------------
>39825_39825_12_INPP5B-TRIT1_INPP5B_chr1_38351310_ENST00000373027_TRIT1_chr1_40313332_ENST00000441669_length(transcript)=2146nt_BP=864nt
GCGGCGGGATGAGGAGCTTGAGGAAGCAGGCAGGGAAATGTCTGCCGCCGCCGGCTCTCGGGAGCGCAACACTGCAGGTGGTTCTAACTT
TGATGGTTTGAGACCAAATGGGAAGGGAGTGCCTATGGACCAAAGCTCCAGGGGTCAAGATAAACCAGAAAGCTTGCAACCAAGACAGAA
TAAATCCAAGTCCGAAATTACTGACATGGTTCGCTCCTCCACTATCACAGTGTCGGACAAGGCTCATATTTTATCCATGCAGAAGTTTGG
ACTGCGAGATACAATTGTGAAATCACATCTACTACAGAAAGAAGAGGATTACACCTATATCCAGAACTTCAGGTTTTTTGCGGGAACATA
CAATGTAAATGGGCAGTCCCCCAAAGAATGCCTCCGGCTGTGGCTGAGCAATGGTATCCAGGCCCCAGATGTCTATTGTGTAGGGTTCCA
GGAGCTTGATCTGAGTAAGGAAGCTTTTTTCTTTCACGATACCCCAAAGGAGGAAGAGTGGTTCAAAGCTGTGTCAGAGGGTCTTCATCC
AGATGCCAAATATGCAAAGGTGAAGCTTATCCGACTGGTTGGGATTATGCTGCTGTTATATGTCAAACAGGAGCATGCAGCTTATATCTC
AGAAGTGGAAGCCGAGACTGTGGGGACAGGAATCATGGGGAGGATGGGCAACAAGGGAGGCGTGGCGATCAGGTTCCAGTTCCACAACAC
CAGCATCTGCGTTGTGAATTCTCACTTGGCAGCCCACATTGAAGAGTATGAGAGGAGGAACCAGGACTATAAGGACATTTGTTCTCGAAT
GCAGTTTTGTCAGCCTGACCCAAGCCTTCCCCCTCTCACCATCAGCAACCATGACCAGGACTATCAACATGGTATCTTCCAATCAATTGG
CTTCAAGGAATTTCACGAGTACCTGATCACTGAGGGAAAATGCACACTGGAGACTAGTAACCAGCTTCTAAAGAAAGGTATTGAGGCTCT
GAAACAAGTAACTAAGAGATATGCCCGGAAACAAAACCGATGGGTTAAAAACCGTTTTTTGAGCAGACCTGGTCCCATTGTCCCCCCTGT
CTATGGCTTAGAGGTATCTGATGTCTCGAAGTGGGAAGAGTCTGTTCTTGAACCTGCTCTTGAAATCGTGCAAAGTTTCATCCAGGGCCA
CAAGCCTACAGCCACTCCAATAAAGATGCCATACAATGAAGCTGAGAACAAGAGAAGTTATCACCTGTGTGACCTCTGTGATCGAATCAT
CATTGGGGATCGCGAATGGGCAGCGCACATAAAATCCAAATCCCACTTGAACCAACTGAAGAAAAGAAGAAGATTGGACTCAGATGCTGT
CAACACCATAGAAAGTCAGAGTGTTTCCCCAGACCATAACAAAGAACCTAAAGAGAAGGGATCCCCAGGGCAGAATGATCAAGAGCTGAA
ATGCAGCGTTTAAGAGACATGTCCAGTGGCCTTTGGAAAGGTGGTGGGGATCCAGTTCAGGAGGGAGGGGTATGTTTGTCTCCCAGTCTG
GGCAAAGGAGTGCTATGCGGAATTCTCTGCATAGCAGAAAAGCTCCCACCATTTTCTTTTGATGTGGTTTTAAAGTCTCACGTTCTCTAT
AATAGAAACAGCAGGTCTTGTCAGCTCCTTGTGTGGCTGATGTGTCTGGAAATGATGTAGTTCAGGAAAGCATTTTTTTTTTCTTTGAAC
CTTAAAGGTTCTATTATTAAAAGCAGCACAGATTCCACATTTTTATACATGAGGATCTTCTTTGTGGTGAATACCAGGATTGACTGCATC
CCTTTAAAGAAGTTTTATGTCCCTGACTCTGGCTAAAATTATCTAATTTCCAGATGCTTTTGTAGATGACTGAAGTATTTGTGAGCCACA
TATTGGGAGTTCTAGATTTGAGTGAATGGCAGGAAAGGGCCATCTCCATTGAGATGATTAAGTGAACCAAACTAGTTCTCAGAATTCTAC
AGAGAAGGAGGGAATCAGACTGAGGAAGCTGTGACATAGGACTTGAAGACCAAAGACTTTGAAATTTGCGAGCTGCTCATGTGTGAGTTA

>39825_39825_12_INPP5B-TRIT1_INPP5B_chr1_38351310_ENST00000373027_TRIT1_chr1_40313332_ENST00000441669_length(amino acids)=471AA_BP=276
MSAAAGSRERNTAGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQ
KEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRL
VGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPL
TISNHDQDYQHGIFQSIGFKEFHEYLITEGKCTLETSNQLLKKGIEALKQVTKRYARKQNRWVKNRFLSRPGPIVPPVYGLEVSDVSKWE
ESVLEPALEIVQSFIQGHKPTATPIKMPYNEAENKRSYHLCDLCDRIIIGDREWAAHIKSKSHLNQLKKRRRLDSDAVNTIESQSVSPDH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for INPP5B-TRIT1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Still interaction with
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000441669		3	9	233_255	189.66666666666666	386.0	isopentenylpyrophosphate transferase
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000441669		3	9	233_255	189.66666666666666	386.0	isopentenylpyrophosphate transferase
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000316891		5	11	281_283	271.6666666666667	468.0	substrate tRNA
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000316891		5	11	313_331	271.6666666666667	468.0	substrate tRNA
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000316891		5	11	323_330	271.6666666666667	468.0	substrate tRNA
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000372818		5	10	281_283	271.6666666666667	442.0	substrate tRNA
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000372818		5	10	313_331	271.6666666666667	442.0	substrate tRNA
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000372818		5	10	323_330	271.6666666666667	442.0	substrate tRNA
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000441669		3	9	281_283	189.66666666666666	386.0	substrate tRNA
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000441669		3	9	313_331	189.66666666666666	386.0	substrate tRNA
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000441669		3	9	323_330	189.66666666666666	386.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000316891		5	11	281_283	271.6666666666667	468.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000316891		5	11	313_331	271.6666666666667	468.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000316891		5	11	323_330	271.6666666666667	468.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000372818		5	10	281_283	271.6666666666667	442.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000372818		5	10	313_331	271.6666666666667	442.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000372818		5	10	323_330	271.6666666666667	442.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000441669		3	9	281_283	189.66666666666666	386.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000441669		3	9	313_331	189.66666666666666	386.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000441669		3	9	323_330	189.66666666666666	386.0	substrate tRNA

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000316891		5	11	233_255	271.6666666666667	468.0	isopentenylpyrophosphate transferase
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000372818		5	10	233_255	271.6666666666667	442.0	isopentenylpyrophosphate transferase
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000316891		5	11	233_255	271.6666666666667	468.0	isopentenylpyrophosphate transferase
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000372818		5	10	233_255	271.6666666666667	442.0	isopentenylpyrophosphate transferase
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000316891		5	11	183_187	271.6666666666667	468.0	substrate tRNA
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000316891		5	11	55_58	271.6666666666667	468.0	substrate tRNA
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000372818		5	10	183_187	271.6666666666667	442.0	substrate tRNA
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000372818		5	10	55_58	271.6666666666667	442.0	substrate tRNA
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000441669		3	9	183_187	189.66666666666666	386.0	substrate tRNA
Tgene	TRIT1	chr1:38351309	chr1:40313332	ENST00000441669		3	9	55_58	189.66666666666666	386.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000316891		5	11	183_187	271.6666666666667	468.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000316891		5	11	55_58	271.6666666666667	468.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000372818		5	10	183_187	271.6666666666667	442.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000372818		5	10	55_58	271.6666666666667	442.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000441669		3	9	183_187	189.66666666666666	386.0	substrate tRNA
Tgene	TRIT1	chr1:38351310	chr1:40313332	ENST00000441669		3	9	55_58	189.66666666666666	386.0	substrate tRNA

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for INPP5B-TRIT1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for INPP5B-TRIT1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source