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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:INTS1-GET4 (FusionGDB2 ID:39916) |
Fusion Gene Summary for INTS1-GET4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: INTS1-GET4 | Fusion gene ID: 39916 | Hgene | Tgene | Gene symbol | INTS1 | GET4 | Gene ID | 26173 | 51608 |
| Gene name | integrator complex subunit 1 | guided entry of tail-anchored proteins factor 4 | |
| Synonyms | INT1|NDCAGF|NET28 | C7orf20|CEE|CGI-20|TRC35 | |
| Cytomap | 7p22.3 | 7p22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | integrator complex subunit 1 | Golgi to ER traffic protein 4 homologH_NH1244M04.5conserved edge expressed proteinconserved edge proteingolgi to ER traffic protein 4transmembrane domain recognition complex 35 kDa subunittransmembrane domain recognition complex, 35kDa | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q8N201 | Q7L5D6 | |
| Ensembl transtripts involved in fusion gene | ENST00000389470, ENST00000404767, ENST00000493531, | ENST00000265857, ENST00000407192, | |
| Fusion gene scores | * DoF score | 11 X 9 X 9=891 | 14 X 5 X 8=560 |
| # samples | 14 | 14 | |
| ** MAII score | log2(14/891*10)=-2.66999860457696 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(14/560*10)=-2 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: INTS1 [Title/Abstract] AND GET4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | INTS1(1510482)-GET4(930565), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | INTS1 | GO:0016180 | snRNA processing | 16239144 |
| Tgene | GET4 | GO:0071816 | tail-anchored membrane protein insertion into ER membrane | 25535373 |
| Fusion gene breakpoints across INTS1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across GET4 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | PRAD | TCGA-EJ-5497-01A | INTS1 | chr7 | 1510482 | - | GET4 | chr7 | 930565 | + |
| ChimerDB4 | PRAD | TCGA-EJ-5497 | INTS1 | chr7 | 1510482 | - | GET4 | chr7 | 930565 | + |
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Fusion Gene ORF analysis for INTS1-GET4 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000389470 | ENST00000265857 | INTS1 | chr7 | 1510482 | - | GET4 | chr7 | 930565 | + |
| In-frame | ENST00000389470 | ENST00000407192 | INTS1 | chr7 | 1510482 | - | GET4 | chr7 | 930565 | + |
| In-frame | ENST00000404767 | ENST00000265857 | INTS1 | chr7 | 1510482 | - | GET4 | chr7 | 930565 | + |
| In-frame | ENST00000404767 | ENST00000407192 | INTS1 | chr7 | 1510482 | - | GET4 | chr7 | 930565 | + |
| intron-3CDS | ENST00000493531 | ENST00000265857 | INTS1 | chr7 | 1510482 | - | GET4 | chr7 | 930565 | + |
| intron-3CDS | ENST00000493531 | ENST00000407192 | INTS1 | chr7 | 1510482 | - | GET4 | chr7 | 930565 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000404767 | INTS1 | chr7 | 1510482 | - | ENST00000265857 | GET4 | chr7 | 930565 | + | 8073 | 6543 | 86 | 7060 | 2324 |
| ENST00000404767 | INTS1 | chr7 | 1510482 | - | ENST00000407192 | GET4 | chr7 | 930565 | + | 8075 | 6543 | 86 | 7060 | 2324 |
| ENST00000389470 | INTS1 | chr7 | 1510482 | - | ENST00000265857 | GET4 | chr7 | 930565 | + | 8599 | 7069 | 0 | 7586 | 2528 |
| ENST00000389470 | INTS1 | chr7 | 1510482 | - | ENST00000407192 | GET4 | chr7 | 930565 | + | 8601 | 7069 | 0 | 7586 | 2528 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000404767 | ENST00000265857 | INTS1 | chr7 | 1510482 | - | GET4 | chr7 | 930565 | + | 0.005025686 | 0.9949744 |
| ENST00000404767 | ENST00000407192 | INTS1 | chr7 | 1510482 | - | GET4 | chr7 | 930565 | + | 0.005019111 | 0.9949809 |
| ENST00000389470 | ENST00000265857 | INTS1 | chr7 | 1510482 | - | GET4 | chr7 | 930565 | + | 0.005563059 | 0.994437 |
| ENST00000389470 | ENST00000407192 | INTS1 | chr7 | 1510482 | - | GET4 | chr7 | 930565 | + | 0.005558047 | 0.9944419 |
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Fusion Genomic Features for INTS1-GET4 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| INTS1 | chr7 | 1510481 | - | GET4 | chr7 | 930564 | + | 0.2682124 | 0.73178756 |
| INTS1 | chr7 | 1510481 | - | GET4 | chr7 | 930564 | + | 0.2682124 | 0.73178756 |
| INTS1 | chr7 | 1510481 | - | GET4 | chr7 | 930564 | + | 0.2682124 | 0.73178756 |
| INTS1 | chr7 | 1510481 | - | GET4 | chr7 | 930564 | + | 0.2682124 | 0.73178756 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for INTS1-GET4 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:1510482/chr7:930565) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| INTS1 | GET4 |
| FUNCTION: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). {ECO:0000269|PubMed:23904267, ECO:0000305|PubMed:16239144}. | FUNCTION: As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation (PubMed:20676083, PubMed:21636303, PubMed:21743475, PubMed:28104892). The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum (PubMed:20676083, PubMed:28104892, PubMed:25535373). Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome (PubMed:28104892). Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum (PubMed:21743475). The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome (PubMed:21636303). {ECO:0000269|PubMed:20676083, ECO:0000269|PubMed:21636303, ECO:0000269|PubMed:21743475, ECO:0000269|PubMed:25535373, ECO:0000269|PubMed:28104892}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | INTS1 | chr7:1510482 | chr7:930565 | ENST00000404767 | - | 47 | 48 | 1580_1583 | 2152 | 2191.0 | Compositional bias | Note=Poly-Val |
| Hgene | INTS1 | chr7:1510482 | chr7:930565 | ENST00000404767 | - | 47 | 48 | 1875_1878 | 2152 | 2191.0 | Compositional bias | Note=Poly-Leu |
| Hgene | INTS1 | chr7:1510482 | chr7:930565 | ENST00000404767 | - | 47 | 48 | 61_64 | 2152 | 2191.0 | Compositional bias | Note=Poly-Ala |
| Hgene | INTS1 | chr7:1510482 | chr7:930565 | ENST00000404767 | - | 47 | 48 | 1159_1179 | 2152 | 2191.0 | Transmembrane | Helical |
| Tgene | GET4 | chr7:1510482 | chr7:930565 | ENST00000265857 | 3 | 9 | 195_271 | 155 | 328.0 | Region | Interacts with BAG6 | |
| Tgene | GET4 | chr7:1510482 | chr7:930565 | ENST00000407192 | 2 | 8 | 195_271 | 102 | 275.0 | Region | Interacts with BAG6 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for INTS1-GET4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >39916_39916_1_INTS1-GET4_INTS1_chr7_1510482_ENST00000389470_GET4_chr7_930565_ENST00000265857_length(transcript)=8599nt_BP=7069nt ATGTGGTTAAGTGGCAAAAGCCAGGTGCAGAAAAGAGGAGCCGTGCGCTACCTGCAGGCACCACCTGTGAATGGAGAGGCCAGCGCCTGC CCCGCGCCGCCGACCCACCTGGACCGGACCACATGCGCGCGGCGCCGGCCAGCCCGCCTCCCGCCGCCATGGGGCGCTGCAGGCATCAGG CCGGCGCCGCGGGCCTCTCGCGCCTCCTTCTGGGCCCGCTTCCCGCCGCACTGTTTTCCTTCCGGTTGTTCCGGAAGTCGGGTCCTCGAG GGCGGTGAGATCGGTTTCCGATTCCGGGGTGGCCGGGTGGCGGCGGCGGCGCTCCGGTCGCGATGGGCCAGAGGTGACGCCGCAGCCGCC GGGAGCCGCGAGGGACGGGGCAGGATGAACCGGGCCAAGCCCACCACGGTGCGCCGGCCCAGCGCCGCGGCCAAACCCTCAGGGCACCCT CCCCCAGGAGACTTCATTGCTCTGGGCTCAAAGGGTCAGGCCAATGAATCGAAAACGGCGTCCACCCTGCTGAAGCCAGCCCCTTCCGGC CTGCCTTCTGAGCGCAAGCGGGATGCGGCGGCCGCGTTGTCCAGTGCCTCGGCCCTCACCGGTCTCACCAAACGCCCCAAACTCTCCTCC ACACCCCCTCTGAGTGCCCTGGGGCGCCTGGCTGAGGCTGCAGTGGCAGAAAAACGAGCCATTTCTCCGTCGATTAAAGAGCCATCTGTG GTGCCAATTGAAGTGCTGCCCACGGTGCTGCTGGATGAGATCGAGGCGGCCGAGCTGGAGGGCAACGATGACAGGATCGAGGGCGTGCTG TGCGGGGCCGTGAAGCAGCTGAAGGTCACCCGCGCCAAGCCTGACAGCACCCTCTACCTGAGCCTCATGTACCTGGCCAAGATCAAGCCC AACATCTTCGCCACTGAGGGCGTCATTGAGGCTCTGTGTAGCCTCCTGCGGCGGGACGCCTCCATCAACTTCAAGGCCAAGGGGAACAGC CTGGTGTCTGTGCTGGCCTGTAACCTCCTCATGGCCGCCTACGAGGAGGACGAGAACTGGCCCGAGATCTTTGTCAAGGTGTACATCGAG GACTCCCTGGGGGAGCGGATCTGGGTGGACAGCCCTCACTGTAAGACGTTTGTGGACAACATCCAGACGGCCTTCAACACCAGAATGCCC CCCAGGAGCGTGCTGCTGCAGGGGGAGGCGGGCCGCGTTGCGGGCGACCTGGGTGCAGGGAGCAGCCCACACCCCTCCCTCACGGAGGAG GAGGACAGCCAGACGGAGTTGCTGATCGCGGAGGAGAAGCTGAGCCCCGAGCAGGAGGGCCAGCTCATGCCCAGGTACGAAGAGCTCGCG GAGAGCGTGGAGGAGTATGTCCTGGACATGCTGCGGGACCAGCTGAACCGGCGCCAGCCCATCGACAACGTCTCCAGGAACCTCCTGCGG CTCCTCACCTCCACCTGCGGCTATAAGGAGGTGCGGCTGCTGGCGGTGCAGAAGCTGGAGATGTGGCTGCAGAACCCCAAGCTGACCCGG CCGGCCCAGGACCTGCTGATGTCCGTCTGCATGAACTGCAACACGCACGGTTCCGAAGACATGGACGTCATCTCACACCTGATCAAGATC CGCCTCAAGCCCAAGGTCCTCCTCAACCACTTCATGCTGTGCATCAGGGAGCTGCTGAGCGCGCACAAGGACAACCTGGGCACCACCATC AAGTTGGTGATCTTCAATGAGCTCTCCAGCGCCCGGAACCCGAACAACATGCAGGTCCTCTATACCGCACTGCAGCACAGCTCAGAGCTG GCGCCCAAGTTCCTGGCCATGGTGTTCCAGGACCTGCTGACCAACAAGGACGACTACCTGCGGGCCTCGCGGGCCCTGCTGCGGGAGATC ATCAAGCAGACCAAGCACGAGATCAACTTCCAGGCCTTCTGCCTGGGGCTCATGCAGGAGCGCAAGGAGCCGCAGTACCTGGAGATGGAG TTCAAGGAGCGCTTCGTGGTGCACATCACCGACGTCCTGGCCGTGTCCATGATGCTGGGCATCACAGCGCAGGTGAAGGAGGCCGGCATC GCCTGGGACAAAGGAGAAAAGAGGAACCTGGAAGTGCTCCGCTCATTCCAGAACCAGATTGCCGCCATCCAGCGGGATGCCGTCTGGTGG CTCCACACTGTGGTCCCCTCCATCAGCAAGCTCGCCCCTAAGGACTACGTGCACTGCCTGCACAAGGTGCTGTTCACAGAGCAGCCGGAG ACCTACTACAAGTGGGACAACTGGCCACCCGAGAGTGACCGCAACTTCTTCCTGCGTCTGTGCTCCGAGGTGCCCATTTTGGAGGACACG CTGATGCGCATCCTGGTCATCGGGCTGTCCCGGGAGCTCCCGCTCGGGCCTGCGGACGCCATGGAGCTTGCTGACCACCTGGTGAAGCGG GCGGCTGCCGTGCAGGCGGATGATGTGGAGGTGCTGAAGGTGGGGAGGACCCAGCTGATCGACGCCGTTCTGAATCTGTGCACCTACCAT CACCCTGAAAACATCCAGCTCCCACCGGGGTACCAGCCTCCGAACCTCGCCATCTCTACCCTCTACTGGAAGGCCTGGCCCCTCCTGCTG GTCGTCGCCGCATTCAACCCAGAGAACATCGGCCTGGCTGCGTGGGAGGAGTACCCGACCCTGAAGATGCTCATGGAGATGGTGATGACC AACAACTACTCCTACCCACCGTGCACCCTGACGGATGAGGAGACCCGGACGGAGATGCTGAACCGTGAGCTGCAGACCGCCCAGCGGGAG AAGCAGGAGATCCTGGCCTTCGAGGGGCACCTGGCGGCCGCGTCCACCAAGCAGACCATCACTGAGAGCAGCAGCCTCCTCCTGTCGCAG CTCACCAGCCTGGACCCCCAGTACGCAGCCCACACAGCCCCGCCCTGCGCCTGCCGTCGGGACCTGGGGCCCCCCCGGAGGCCTCCCCCT CACATCCTGGATCAAGTGAAAAGCCTCAACCAGTCCCTCCGCCTCGGGCACCTCTTGTGCCGCAGCCGAAACCCTGACTTTCTCCTCCAC ATCATCCAGCGGCAGGCCTCCTCGCAGTCCATGCCCTGGCTGGCGGACCTGGTACAGTCCAGCGAGGGCTCCCTGGACGTGCTGCCCGTG CAGTGTCTGTGCGAGTTCCTGCTGCACGATGCTGTGGACGATGCTGCTTCCGGGGAGGAGGACGACGAGGGCGAGAGCAAGGAGCAGAAG GCCAAGAAGCGGCAGAGGCAACAGAAGCAGCGGCAGCTGCTGGGCCGCCTGCAGGACCTGCTACTGGGCCCGAAGGCTGATGAGCAGACC ACGTGTGAGGTGCTGGACTACTTCTTGCGGCGCCTCGGCTCCTCCCAGGTGGCCTCCCGCGTGCTGGCCATGAAGGGTGAGACCCTGCCT GCACTGCCGAAAGCCGGCCCAGCTCATGAGTGTCTGCCACAGGGTTTGTCGCTGGTGCTTTCGGAGGGCAGCCTGCGGGACGGGGAGGAG AAGGAGCCCCCCATGGAGGAGGATGTGGGGGACACAGATGTGCTGCAGGGCTATCAGTGGCTGCTGCGGGACCTGCCTCGCCTGCCTCTG TTCGACAGCGTCAGGAGCACCACAGCCCTGGCCCTGCAGCAGGCAATCCACATGGAGACTGATCCCCAGACCATCAGCGCCTACCTGATC TACTTGTCCCAGCACACGCCTGTGGAGGAGCAGGCCCAGCACAGCGACCTGGCCCTGGACGTGGCCCGGCTGGTCGTGGAGCGCTCCACC ATCATGTCCCACCTCTTCTCGAAGCTCTCCCCGAGTGCCGCGTCGGACGCCGTGCTGAGCGCTCTGTTGTCCATCTTCTCACGCTACGTG AGGCGCATGCGGCAGAGCAAGGAGGGCGAGGAGGTCTACAGCTGGTCGGAGTCTCAGGACCAGGTCTTCCTACGCTGGAGCAGCGGGGAG ACAGCCACCATGCACATCCTCGTGGTCCATGCCATGGTGATCCTGCTGACGCTGGGCCCGCCTCGAGCCGACGACAGCGAGTTCCAGGCG CTGCTGGACATCTGGTTTCCGGAGGAGAAGCCACTGCCCACCGCCTTCCTGGTGGACACATCGGAGGAGGCGCTGCTGCTTCCTGACTGG CTGAAGCTGCGCATGATCCGTTCTGAGGTGCTCCGCCTGGTGGACGCCGCCCTGCAGGACCTGGAGCCGCAGCAGCTGCTGCTGTTCGTG CAGTCGTTTGGCATCCCCGTGTCCAGCATGAGCAAACTCCTCCAGTTCCTGGACCAGGCAGTGGCCCACGACCCCCAGACTCTGGAGCAG AACATCATGGACAAGAGTAAGATGCCAGGGACCTGCGGAGTGGGTTCACACACGCTGACCGAGCCCCAGCCCGGCCAGGCTTTTGGGGCC TGGGTGCGAGCGGGTGTGACCCTGCTACGGTTTGCAGATTACATGGCCCACCTGGTGGAGGTCCAGCATGAGCGCGGCGCCTCCGGAGGC CAGACTTTCCACTCCTTGCTCACAGCCTCCCTGCCGCCCCGCCGAGACAGCACAGAGGCACCCAAACCAAAGAGCAGCCCAGAGCAGCCC ATAGGCCAGGGCCGGATTCGGGTGGGGACCCAGCTCCGGGTGCTGGGCCCTGAGGACGACCTGGCTGGCATGTTCCTCCAGATTTTCCCG CTCAGCCCGGACCCTCGGTGGCAGAGCTCCAGTCCCCGCCCCGTGGCCCTCGCCCTGCAGCAGGCCCTGGGCCAGGAGCTGGCCCGCGTC GTCCAGGGCAGCCCCGAGGTGCCGGGCATCACGGTGCGTGTCCTGCAGGCCCTCGCCACCCTGCTCAGCTCCCCACACGGCGGTGCCCTG GTGATGTCCATGCACCGTAGCCACTTCCTGGCCTGCCCGCTGCTGCGCCAGCTCTGCCAGTACCAGCGCTGTGTGCCACAGGACACCGGC TTCTCCTCGCTCTTCCTGAAGGTGCTCCTGCAGATGCTGCAGTGGCTGGACAGCCCTGGCGTGGAGGGCGGGCCCCTGCGGGCACAGCTC AGGATGCTTGCCAGCCAGGCCTCAGCCGGGCGCAGGCTCAGTGATGTGCGAGGGGGGCTCCTGCGCCTGGCCGAGGCCCTGGCCTTCCGT CAGGACCTGGAGGTGGTCAGCTCCACCGTCCGTGCCGTCATCGCCACCCTGAGGTCTGGGGAGCAGTGCAGCGTGGAGCCGGACCTGATC AGCAAAGTCCTCCAGGGGCTGATCGAGGTGAGGTCCCCCCACCTGGAGGAGCTGCTGACTGCATTCTTCTCTGCCACTGCGGATGCTGCC TCCCCGTTTCCAGCCTGTAAGCCCGTTGTGGTGGTGAGCTCCCTGCTGCTGCAGGAGGAGGAGCCCCTGGCTGGGGGGAAGCCGGGTGCG GACGGTGGCAGCCTGGAGGCCGTGCGGCTGGGGCCCTCGTCAGGCCTCCTAGTGGACTGGCTGGAAATGCTGGACCCCGAGGTGGTCAGC AGCTGCCCCGACCTGCAGCTCAGGCTGCTCTTCTCCCGGAGGAAGGGCAAAGGTCAGGCCCAGGTGCCCTCGTTCCGTCCCTACCTCCTG ACCCTCTTCACGCATCAGTCCAGCTGGCCCACACTGCACCAGTGCATCCGAGTCCTGCTGGGCAAGAGCCGGGAACAGAGGTTCGACCCC TCTGCCTCTCTGGACTTCCTCTGGGCCTGCATCCATGTTCCTCGCATCTGGCAGGGGCGGGACCAGCGCACCCCGCAGGCAGGTCTTGGG AGGAAGCGGCGGGAGGAGCTGGTGCTGCGGGTCCAGGGCCCGGAGCTCATCAGCCTGGTGGAGCTGATCCTGGCCGAGGCGGAGACGCGG AGCCAGGACGGGGACACAGCCGCCTGCAGCCTCATCCAGGCCCGGCTGCCCCTGCTGCTCAGCTGCTGCTGTGGGGACGATGAGAGTGTC AGGAAGGTGACGGAGCACCTGTCAGGCTGCATCCAGCAGTGGGGAGACAGCGTGCTGGGCAGGCGCTGCCGAGACCTTCTCCTGCAGCTC TACCTACAGCGGCCGGAGCTGCGGGTGCCCGTGCCTGAGGTCCTACTGCACAGCGAAGGGGCTGCCAGCAGCAGCGTCTGCAAGCTGGAC GGACTCATCCACCGCTTCATCACGCTCCTTGCGGACACCAGCGACTCCCGGGCGTTGGAGAACCGAGGGGCGGATGCCAGCATGGCCTGC CGGAAGCTGGCGGTGGCGCACCCGCTGCTGCTGCTCAGGCACCTGCCCATGATCGCGGCGCTCCTGCACGGCCGCACCCACCTCAACTTC CAGGAGTTCCGGCAGCAGAACCACCTGAGCTGCTTCCTGCACGTGCTGGGCCTGCTGGAGCTGCTGCAGCCGCACGTGTTCCGCAGCGAG CACCAGGGGGCGCTGTGGGACTGCCTTCTGTCCTTCATCCGCCTGCTGCTGAATTACAGGAAGTCCTCCCGCCATCTGGCTGCCTTCATC AACAAGTTTGTGCAGTTCATCCATAAGTACATTACCTACAATGCCCCAGCAGCCATCTCCTTCCTGCAGAAGCACGCCGACCCGCTCCAC GACCTGTCCTTCGACAACAGTGACCTGGTGATGCTGAAATCCCTCCTTGCAGGGCTCAGCCTGCCCAGCAGGGACGACAGGACCGACCGA GGCCTGGACGAAGAGGGCGAGGAGGAGAGCTCAGCCGGCTCCTTGCCCCTGGTCAGCGTCTCCCTGTTCACCCCTCTGACCGCGGCCGAG ATGGCCCCCTACATGAAACGGCTTTCCCGGGGCCAAACGGTGGAGGATCTGCTGGAGGTTCTGAGTGACATAGACGAGATGTCCCGGCGG AGACCCGAGATCCTGAGCTTCTTCTCGACCAACCTGCAGCGGCTGATGAGCTCGGCCGAGGAGTGTTGCCGCAACCTCGCCTTCAGCCTG GCCCTGCGCTCCATGCAGAACAGCCCCAGCATTGCAGCCGCTTTCCTGCCCACGTTCATGTACTGCCTGGGCAGCCAGGACTTTGAGGTG GTGCAGACGGCCCTCCGGAACCTGCCTGAGTACGCTCTCCTGTGCCAAGAACAAAACTATTGTGAGTCGAGGTATCATTTTCTGCACTCA GCGGACGGGGAGGGCTGTGCCAACATGCTGGTGGAGTATTCCACGTCCCGCGGCTTCCGCAGCGAGGTGGACATGTTCGTGGCCCAGGCC GTGCTACAGTTTCTCTGTTTAAAAAACAAAAGTAGCGCATCGGTGGTCTTCACGACGTACACCCAGAAGCACCCGTCCATCGAGGACGGG CCTCCGTTTGTGGAGCCGCTGCTTAACTTCATCTGGTTCCTGCTGCTGGCTGTGGACGGTGGGAAGCTGACGGTGTTCACTGTGCTGTGT GAGCAGTACCAGCCATCCCTCCGGCGGGACCCCATGTACAACGAGTACCTCGACCGCATAGGACAGCTGTTCTTCGGCGTCCCGCCCAAG CAGACGTCTTCCTACGGGGGCCTGCTCGGGAACCTTCTGACCAGCCTCATGGGCTCCTCAGAGCAGGAGGATGGGGAGGAGAGCCCCAGC GACGGCAGCCCCATCGAGCTGGACTGAACTGGCCAGGCCACGTGGAGACACCACGGTCGACGACGGCTGGAGGGACGTTTCAGAGGCGAG TCCTGGGTGGCTCCTCGCCTTGGGGGCTCCTGGCCCTGAGGCTGGCGGTGGCCGCATGCCGGCGCGTGTCTGTTTCTGTGCGGCGGCTCA GGGTGGCGCGGCTGCTGCTCACTGTGCTGCTGGGACCCAAGAGTGGGGCGTCGCCCCTGCTGGCCGCCGCGTCCCCCGAGATTGACCCAC AATAAAGCACAGGCCTTACCGCGGCGTCACCCTCTCCCACTCCTTTGTTCTGGGTCCTTTCGGGAGGGCTGATGGGCAGCACAGGAGGCC CGTCCTCGGGGGGCTGCGCACATCACGCTCCTTGCCGGGCGTCCGGCACAGCTGCGGTCACCAAAGCAGGTGCTGGCCCTCGGACCTGAG AGCCCAGCCAGGGCCCATGTGGTCTGCAAATGGGAGCGGCTGTTTTTGAACACGGGGTCATTCTGCAGTCAGGACGAACCGGTCCCCGTC GCAGACGGAGTGCACGTGCCCTGCGCCACATCCTCACGCTCGGTGGAGGGACGCGTGCGGCGGGACGGTGCCTACGGGTACTTGCAGCTG TGTCCCATGTGGCATCCCAGAGCTGCGCCCTGCTGGTCTCTGTGAGCGCCACGCTGCTGTGCTGGAAATGCCGCTTTAAAAAGGGATACC GTGGGACTCTGCCCGTCTCTTTCATAACGCAATATTTATTTGTATTGGGTGATGATTGATTCTTTCGACCTAACATTTTGGGTTTTAACC AAATAACCGGTCCAGGAGTGAGCAGCTCCGTTCTGTCAGATGCTACTCCAAATGTTACCAGAACGATGACAAAAGGGGAGACGCTCTATT TTTTCACAGTTAAATGACAGTTGTAGATTGATACGCAGTTGTGCATGGGAAGGGGAAACGCACAGCTTTATTTACTGTAAAGTGGAATTT >39916_39916_1_INTS1-GET4_INTS1_chr7_1510482_ENST00000389470_GET4_chr7_930565_ENST00000265857_length(amino acids)=2528AA_BP=2356 MWLSGKSQVQKRGAVRYLQAPPVNGEASACPAPPTHLDRTTCARRRPARLPPPWGAAGIRPAPRASRASFWARFPPHCFPSGCSGSRVLE GGEIGFRFRGGRVAAAALRSRWARGDAAAAGSREGRGRMNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQANESKTASTLLKPAPSG LPSERKRDAAAALSSASALTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVL CGAVKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASINFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIE DSLGERIWVDSPHCKTFVDNIQTAFNTRMPPRSVLLQGEAGRVAGDLGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRYEELA ESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTSTCGYKEVRLLAVQKLEMWLQNPKLTRPAQDLLMSVCMNCNTHGSEDMDVISHLIKI RLKPKVLLNHFMLCIRELLSAHKDNLGTTIKLVIFNELSSARNPNNMQVLYTALQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREI IKQTKHEINFQAFCLGLMQERKEPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGIAWDKGEKRNLEVLRSFQNQIAAIQRDAVWW LHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKR AAAVQADDVEVLKVGRTQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMT NNYSYPPCTLTDEETRTEMLNRELQTAQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQYAAHTAPPCACRRDLGPPRRPPP HILDQVKSLNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAVDDAASGEEDDEGESKEQK AKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGETLPALPKAGPAHECLPQGLSLVLSEGSLRDGEE KEPPMEEDVGDTDVLQGYQWLLRDLPRLPLFDSVRSTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQAQHSDLALDVARLVVERST IMSHLFSKLSPSAASDAVLSALLSIFSRYVRRMRQSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRADDSEFQA LLDIWFPEEKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVLRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQFLDQAVAHDPQTLEQ NIMDKSKMPGTCGVGSHTLTEPQPGQAFGAWVRAGVTLLRFADYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPKSSPEQP IGQGRIRVGTQLRVLGPEDDLAGMFLQIFPLSPDPRWQSSSPRPVALALQQALGQELARVVQGSPEVPGITVRVLQALATLLSSPHGGAL VMSMHRSHFLACPLLRQLCQYQRCVPQDTGFSSLFLKVLLQMLQWLDSPGVEGGPLRAQLRMLASQASAGRRLSDVRGGLLRLAEALAFR QDLEVVSSTVRAVIATLRSGEQCSVEPDLISKVLQGLIEVRSPHLEELLTAFFSATADAASPFPACKPVVVVSSLLLQEEEPLAGGKPGA DGGSLEAVRLGPSSGLLVDWLEMLDPEVVSSCPDLQLRLLFSRRKGKGQAQVPSFRPYLLTLFTHQSSWPTLHQCIRVLLGKSREQRFDP SASLDFLWACIHVPRIWQGRDQRTPQAGLGRKRREELVLRVQGPELISLVELILAEAETRSQDGDTAACSLIQARLPLLLSCCCGDDESV RKVTEHLSGCIQQWGDSVLGRRCRDLLLQLYLQRPELRVPVPEVLLHSEGAASSSVCKLDGLIHRFITLLADTSDSRALENRGADASMAC RKLAVAHPLLLLRHLPMIAALLHGRTHLNFQEFRQQNHLSCFLHVLGLLELLQPHVFRSEHQGALWDCLLSFIRLLLNYRKSSRHLAAFI NKFVQFIHKYITYNAPAAISFLQKHADPLHDLSFDNSDLVMLKSLLAGLSLPSRDDRTDRGLDEEGEEESSAGSLPLVSVSLFTPLTAAE MAPYMKRLSRGQTVEDLLEVLSDIDEMSRRRPEILSFFSTNLQRLMSSAEECCRNLAFSLALRSMQNSPSIAAAFLPTFMYCLGSQDFEV VQTALRNLPEYALLCQEQNYCESRYHFLHSADGEGCANMLVEYSTSRGFRSEVDMFVAQAVLQFLCLKNKSSASVVFTTYTQKHPSIEDG PPFVEPLLNFIWFLLLAVDGGKLTVFTVLCEQYQPSLRRDPMYNEYLDRIGQLFFGVPPKQTSSYGGLLGNLLTSLMGSSEQEDGEESPS -------------------------------------------------------------- >39916_39916_2_INTS1-GET4_INTS1_chr7_1510482_ENST00000389470_GET4_chr7_930565_ENST00000407192_length(transcript)=8601nt_BP=7069nt ATGTGGTTAAGTGGCAAAAGCCAGGTGCAGAAAAGAGGAGCCGTGCGCTACCTGCAGGCACCACCTGTGAATGGAGAGGCCAGCGCCTGC CCCGCGCCGCCGACCCACCTGGACCGGACCACATGCGCGCGGCGCCGGCCAGCCCGCCTCCCGCCGCCATGGGGCGCTGCAGGCATCAGG CCGGCGCCGCGGGCCTCTCGCGCCTCCTTCTGGGCCCGCTTCCCGCCGCACTGTTTTCCTTCCGGTTGTTCCGGAAGTCGGGTCCTCGAG GGCGGTGAGATCGGTTTCCGATTCCGGGGTGGCCGGGTGGCGGCGGCGGCGCTCCGGTCGCGATGGGCCAGAGGTGACGCCGCAGCCGCC GGGAGCCGCGAGGGACGGGGCAGGATGAACCGGGCCAAGCCCACCACGGTGCGCCGGCCCAGCGCCGCGGCCAAACCCTCAGGGCACCCT CCCCCAGGAGACTTCATTGCTCTGGGCTCAAAGGGTCAGGCCAATGAATCGAAAACGGCGTCCACCCTGCTGAAGCCAGCCCCTTCCGGC CTGCCTTCTGAGCGCAAGCGGGATGCGGCGGCCGCGTTGTCCAGTGCCTCGGCCCTCACCGGTCTCACCAAACGCCCCAAACTCTCCTCC ACACCCCCTCTGAGTGCCCTGGGGCGCCTGGCTGAGGCTGCAGTGGCAGAAAAACGAGCCATTTCTCCGTCGATTAAAGAGCCATCTGTG GTGCCAATTGAAGTGCTGCCCACGGTGCTGCTGGATGAGATCGAGGCGGCCGAGCTGGAGGGCAACGATGACAGGATCGAGGGCGTGCTG TGCGGGGCCGTGAAGCAGCTGAAGGTCACCCGCGCCAAGCCTGACAGCACCCTCTACCTGAGCCTCATGTACCTGGCCAAGATCAAGCCC AACATCTTCGCCACTGAGGGCGTCATTGAGGCTCTGTGTAGCCTCCTGCGGCGGGACGCCTCCATCAACTTCAAGGCCAAGGGGAACAGC CTGGTGTCTGTGCTGGCCTGTAACCTCCTCATGGCCGCCTACGAGGAGGACGAGAACTGGCCCGAGATCTTTGTCAAGGTGTACATCGAG GACTCCCTGGGGGAGCGGATCTGGGTGGACAGCCCTCACTGTAAGACGTTTGTGGACAACATCCAGACGGCCTTCAACACCAGAATGCCC CCCAGGAGCGTGCTGCTGCAGGGGGAGGCGGGCCGCGTTGCGGGCGACCTGGGTGCAGGGAGCAGCCCACACCCCTCCCTCACGGAGGAG GAGGACAGCCAGACGGAGTTGCTGATCGCGGAGGAGAAGCTGAGCCCCGAGCAGGAGGGCCAGCTCATGCCCAGGTACGAAGAGCTCGCG GAGAGCGTGGAGGAGTATGTCCTGGACATGCTGCGGGACCAGCTGAACCGGCGCCAGCCCATCGACAACGTCTCCAGGAACCTCCTGCGG CTCCTCACCTCCACCTGCGGCTATAAGGAGGTGCGGCTGCTGGCGGTGCAGAAGCTGGAGATGTGGCTGCAGAACCCCAAGCTGACCCGG CCGGCCCAGGACCTGCTGATGTCCGTCTGCATGAACTGCAACACGCACGGTTCCGAAGACATGGACGTCATCTCACACCTGATCAAGATC CGCCTCAAGCCCAAGGTCCTCCTCAACCACTTCATGCTGTGCATCAGGGAGCTGCTGAGCGCGCACAAGGACAACCTGGGCACCACCATC AAGTTGGTGATCTTCAATGAGCTCTCCAGCGCCCGGAACCCGAACAACATGCAGGTCCTCTATACCGCACTGCAGCACAGCTCAGAGCTG GCGCCCAAGTTCCTGGCCATGGTGTTCCAGGACCTGCTGACCAACAAGGACGACTACCTGCGGGCCTCGCGGGCCCTGCTGCGGGAGATC ATCAAGCAGACCAAGCACGAGATCAACTTCCAGGCCTTCTGCCTGGGGCTCATGCAGGAGCGCAAGGAGCCGCAGTACCTGGAGATGGAG TTCAAGGAGCGCTTCGTGGTGCACATCACCGACGTCCTGGCCGTGTCCATGATGCTGGGCATCACAGCGCAGGTGAAGGAGGCCGGCATC GCCTGGGACAAAGGAGAAAAGAGGAACCTGGAAGTGCTCCGCTCATTCCAGAACCAGATTGCCGCCATCCAGCGGGATGCCGTCTGGTGG CTCCACACTGTGGTCCCCTCCATCAGCAAGCTCGCCCCTAAGGACTACGTGCACTGCCTGCACAAGGTGCTGTTCACAGAGCAGCCGGAG ACCTACTACAAGTGGGACAACTGGCCACCCGAGAGTGACCGCAACTTCTTCCTGCGTCTGTGCTCCGAGGTGCCCATTTTGGAGGACACG CTGATGCGCATCCTGGTCATCGGGCTGTCCCGGGAGCTCCCGCTCGGGCCTGCGGACGCCATGGAGCTTGCTGACCACCTGGTGAAGCGG GCGGCTGCCGTGCAGGCGGATGATGTGGAGGTGCTGAAGGTGGGGAGGACCCAGCTGATCGACGCCGTTCTGAATCTGTGCACCTACCAT CACCCTGAAAACATCCAGCTCCCACCGGGGTACCAGCCTCCGAACCTCGCCATCTCTACCCTCTACTGGAAGGCCTGGCCCCTCCTGCTG GTCGTCGCCGCATTCAACCCAGAGAACATCGGCCTGGCTGCGTGGGAGGAGTACCCGACCCTGAAGATGCTCATGGAGATGGTGATGACC AACAACTACTCCTACCCACCGTGCACCCTGACGGATGAGGAGACCCGGACGGAGATGCTGAACCGTGAGCTGCAGACCGCCCAGCGGGAG AAGCAGGAGATCCTGGCCTTCGAGGGGCACCTGGCGGCCGCGTCCACCAAGCAGACCATCACTGAGAGCAGCAGCCTCCTCCTGTCGCAG CTCACCAGCCTGGACCCCCAGTACGCAGCCCACACAGCCCCGCCCTGCGCCTGCCGTCGGGACCTGGGGCCCCCCCGGAGGCCTCCCCCT CACATCCTGGATCAAGTGAAAAGCCTCAACCAGTCCCTCCGCCTCGGGCACCTCTTGTGCCGCAGCCGAAACCCTGACTTTCTCCTCCAC ATCATCCAGCGGCAGGCCTCCTCGCAGTCCATGCCCTGGCTGGCGGACCTGGTACAGTCCAGCGAGGGCTCCCTGGACGTGCTGCCCGTG CAGTGTCTGTGCGAGTTCCTGCTGCACGATGCTGTGGACGATGCTGCTTCCGGGGAGGAGGACGACGAGGGCGAGAGCAAGGAGCAGAAG GCCAAGAAGCGGCAGAGGCAACAGAAGCAGCGGCAGCTGCTGGGCCGCCTGCAGGACCTGCTACTGGGCCCGAAGGCTGATGAGCAGACC ACGTGTGAGGTGCTGGACTACTTCTTGCGGCGCCTCGGCTCCTCCCAGGTGGCCTCCCGCGTGCTGGCCATGAAGGGTGAGACCCTGCCT GCACTGCCGAAAGCCGGCCCAGCTCATGAGTGTCTGCCACAGGGTTTGTCGCTGGTGCTTTCGGAGGGCAGCCTGCGGGACGGGGAGGAG AAGGAGCCCCCCATGGAGGAGGATGTGGGGGACACAGATGTGCTGCAGGGCTATCAGTGGCTGCTGCGGGACCTGCCTCGCCTGCCTCTG TTCGACAGCGTCAGGAGCACCACAGCCCTGGCCCTGCAGCAGGCAATCCACATGGAGACTGATCCCCAGACCATCAGCGCCTACCTGATC TACTTGTCCCAGCACACGCCTGTGGAGGAGCAGGCCCAGCACAGCGACCTGGCCCTGGACGTGGCCCGGCTGGTCGTGGAGCGCTCCACC ATCATGTCCCACCTCTTCTCGAAGCTCTCCCCGAGTGCCGCGTCGGACGCCGTGCTGAGCGCTCTGTTGTCCATCTTCTCACGCTACGTG AGGCGCATGCGGCAGAGCAAGGAGGGCGAGGAGGTCTACAGCTGGTCGGAGTCTCAGGACCAGGTCTTCCTACGCTGGAGCAGCGGGGAG ACAGCCACCATGCACATCCTCGTGGTCCATGCCATGGTGATCCTGCTGACGCTGGGCCCGCCTCGAGCCGACGACAGCGAGTTCCAGGCG CTGCTGGACATCTGGTTTCCGGAGGAGAAGCCACTGCCCACCGCCTTCCTGGTGGACACATCGGAGGAGGCGCTGCTGCTTCCTGACTGG CTGAAGCTGCGCATGATCCGTTCTGAGGTGCTCCGCCTGGTGGACGCCGCCCTGCAGGACCTGGAGCCGCAGCAGCTGCTGCTGTTCGTG CAGTCGTTTGGCATCCCCGTGTCCAGCATGAGCAAACTCCTCCAGTTCCTGGACCAGGCAGTGGCCCACGACCCCCAGACTCTGGAGCAG AACATCATGGACAAGAGTAAGATGCCAGGGACCTGCGGAGTGGGTTCACACACGCTGACCGAGCCCCAGCCCGGCCAGGCTTTTGGGGCC TGGGTGCGAGCGGGTGTGACCCTGCTACGGTTTGCAGATTACATGGCCCACCTGGTGGAGGTCCAGCATGAGCGCGGCGCCTCCGGAGGC CAGACTTTCCACTCCTTGCTCACAGCCTCCCTGCCGCCCCGCCGAGACAGCACAGAGGCACCCAAACCAAAGAGCAGCCCAGAGCAGCCC ATAGGCCAGGGCCGGATTCGGGTGGGGACCCAGCTCCGGGTGCTGGGCCCTGAGGACGACCTGGCTGGCATGTTCCTCCAGATTTTCCCG CTCAGCCCGGACCCTCGGTGGCAGAGCTCCAGTCCCCGCCCCGTGGCCCTCGCCCTGCAGCAGGCCCTGGGCCAGGAGCTGGCCCGCGTC GTCCAGGGCAGCCCCGAGGTGCCGGGCATCACGGTGCGTGTCCTGCAGGCCCTCGCCACCCTGCTCAGCTCCCCACACGGCGGTGCCCTG GTGATGTCCATGCACCGTAGCCACTTCCTGGCCTGCCCGCTGCTGCGCCAGCTCTGCCAGTACCAGCGCTGTGTGCCACAGGACACCGGC TTCTCCTCGCTCTTCCTGAAGGTGCTCCTGCAGATGCTGCAGTGGCTGGACAGCCCTGGCGTGGAGGGCGGGCCCCTGCGGGCACAGCTC AGGATGCTTGCCAGCCAGGCCTCAGCCGGGCGCAGGCTCAGTGATGTGCGAGGGGGGCTCCTGCGCCTGGCCGAGGCCCTGGCCTTCCGT CAGGACCTGGAGGTGGTCAGCTCCACCGTCCGTGCCGTCATCGCCACCCTGAGGTCTGGGGAGCAGTGCAGCGTGGAGCCGGACCTGATC AGCAAAGTCCTCCAGGGGCTGATCGAGGTGAGGTCCCCCCACCTGGAGGAGCTGCTGACTGCATTCTTCTCTGCCACTGCGGATGCTGCC TCCCCGTTTCCAGCCTGTAAGCCCGTTGTGGTGGTGAGCTCCCTGCTGCTGCAGGAGGAGGAGCCCCTGGCTGGGGGGAAGCCGGGTGCG GACGGTGGCAGCCTGGAGGCCGTGCGGCTGGGGCCCTCGTCAGGCCTCCTAGTGGACTGGCTGGAAATGCTGGACCCCGAGGTGGTCAGC AGCTGCCCCGACCTGCAGCTCAGGCTGCTCTTCTCCCGGAGGAAGGGCAAAGGTCAGGCCCAGGTGCCCTCGTTCCGTCCCTACCTCCTG ACCCTCTTCACGCATCAGTCCAGCTGGCCCACACTGCACCAGTGCATCCGAGTCCTGCTGGGCAAGAGCCGGGAACAGAGGTTCGACCCC TCTGCCTCTCTGGACTTCCTCTGGGCCTGCATCCATGTTCCTCGCATCTGGCAGGGGCGGGACCAGCGCACCCCGCAGGCAGGTCTTGGG AGGAAGCGGCGGGAGGAGCTGGTGCTGCGGGTCCAGGGCCCGGAGCTCATCAGCCTGGTGGAGCTGATCCTGGCCGAGGCGGAGACGCGG AGCCAGGACGGGGACACAGCCGCCTGCAGCCTCATCCAGGCCCGGCTGCCCCTGCTGCTCAGCTGCTGCTGTGGGGACGATGAGAGTGTC AGGAAGGTGACGGAGCACCTGTCAGGCTGCATCCAGCAGTGGGGAGACAGCGTGCTGGGCAGGCGCTGCCGAGACCTTCTCCTGCAGCTC TACCTACAGCGGCCGGAGCTGCGGGTGCCCGTGCCTGAGGTCCTACTGCACAGCGAAGGGGCTGCCAGCAGCAGCGTCTGCAAGCTGGAC GGACTCATCCACCGCTTCATCACGCTCCTTGCGGACACCAGCGACTCCCGGGCGTTGGAGAACCGAGGGGCGGATGCCAGCATGGCCTGC CGGAAGCTGGCGGTGGCGCACCCGCTGCTGCTGCTCAGGCACCTGCCCATGATCGCGGCGCTCCTGCACGGCCGCACCCACCTCAACTTC CAGGAGTTCCGGCAGCAGAACCACCTGAGCTGCTTCCTGCACGTGCTGGGCCTGCTGGAGCTGCTGCAGCCGCACGTGTTCCGCAGCGAG CACCAGGGGGCGCTGTGGGACTGCCTTCTGTCCTTCATCCGCCTGCTGCTGAATTACAGGAAGTCCTCCCGCCATCTGGCTGCCTTCATC AACAAGTTTGTGCAGTTCATCCATAAGTACATTACCTACAATGCCCCAGCAGCCATCTCCTTCCTGCAGAAGCACGCCGACCCGCTCCAC GACCTGTCCTTCGACAACAGTGACCTGGTGATGCTGAAATCCCTCCTTGCAGGGCTCAGCCTGCCCAGCAGGGACGACAGGACCGACCGA GGCCTGGACGAAGAGGGCGAGGAGGAGAGCTCAGCCGGCTCCTTGCCCCTGGTCAGCGTCTCCCTGTTCACCCCTCTGACCGCGGCCGAG ATGGCCCCCTACATGAAACGGCTTTCCCGGGGCCAAACGGTGGAGGATCTGCTGGAGGTTCTGAGTGACATAGACGAGATGTCCCGGCGG AGACCCGAGATCCTGAGCTTCTTCTCGACCAACCTGCAGCGGCTGATGAGCTCGGCCGAGGAGTGTTGCCGCAACCTCGCCTTCAGCCTG GCCCTGCGCTCCATGCAGAACAGCCCCAGCATTGCAGCCGCTTTCCTGCCCACGTTCATGTACTGCCTGGGCAGCCAGGACTTTGAGGTG GTGCAGACGGCCCTCCGGAACCTGCCTGAGTACGCTCTCCTGTGCCAAGAACAAAACTATTGTGAGTCGAGGTATCATTTTCTGCACTCA GCGGACGGGGAGGGCTGTGCCAACATGCTGGTGGAGTATTCCACGTCCCGCGGCTTCCGCAGCGAGGTGGACATGTTCGTGGCCCAGGCC GTGCTACAGTTTCTCTGTTTAAAAAACAAAAGTAGCGCATCGGTGGTCTTCACGACGTACACCCAGAAGCACCCGTCCATCGAGGACGGG CCTCCGTTTGTGGAGCCGCTGCTTAACTTCATCTGGTTCCTGCTGCTGGCTGTGGACGGTGGGAAGCTGACGGTGTTCACTGTGCTGTGT GAGCAGTACCAGCCATCCCTCCGGCGGGACCCCATGTACAACGAGTACCTCGACCGCATAGGACAGCTGTTCTTCGGCGTCCCGCCCAAG CAGACGTCTTCCTACGGGGGCCTGCTCGGGAACCTTCTGACCAGCCTCATGGGCTCCTCAGAGCAGGAGGATGGGGAGGAGAGCCCCAGC GACGGCAGCCCCATCGAGCTGGACTGAACTGGCCAGGCCACGTGGAGACACCACGGTCGACGACGGCTGGAGGGACGTTTCAGAGGCGAG TCCTGGGTGGCTCCTCGCCTTGGGGGCTCCTGGCCCTGAGGCTGGCGGTGGCCGCATGCCGGCGCGTGTCTGTTTCTGTGCGGCGGCTCA GGGTGGCGCGGCTGCTGCTCACTGTGCTGCTGGGACCCAAGAGTGGGGCGTCGCCCCTGCTGGCCGCCGCGTCCCCCGAGATTGACCCAC AATAAAGCACAGGCCTTACCGCGGCGTCACCCTCTCCCACTCCTTTGTTCTGGGTCCTTTCGGGAGGGCTGATGGGCAGCACAGGAGGCC CGTCCTCGGGGGGCTGCGCACATCACGCTCCTTGCCGGGCGTCCGGCACAGCTGCGGTCACCAAAGCAGGTGCTGGCCCTCGGACCTGAG AGCCCAGCCAGGGCCCATGTGGTCTGCAAATGGGAGCGGCTGTTTTTGAACACGGGGTCATTCTGCAGTCAGGACGAACCGGTCCCCGTC GCAGACGGAGTGCACGTGCCCTGCGCCACATCCTCACGCTCGGTGGAGGGACGCGTGCGGCGGGACGGTGCCTACGGGTACTTGCAGCTG TGTCCCATGTGGCATCCCAGAGCTGCGCCCTGCTGGTCTCTGTGAGCGCCACGCTGCTGTGCTGGAAATGCCGCTTTAAAAAGGGATACC GTGGGACTCTGCCCGTCTCTTTCATAACGCAATATTTATTTGTATTGGGTGATGATTGATTCTTTCGACCTAACATTTTGGGTTTTAACC AAATAACCGGTCCAGGAGTGAGCAGCTCCGTTCTGTCAGATGCTACTCCAAATGTTACCAGAACGATGACAAAAGGGGAGACGCTCTATT TTTTCACAGTTAAATGACAGTTGTAGATTGATACGCAGTTGTGCATGGGAAGGGGAAACGCACAGCTTTATTTACTGTAAAGTGGAATTT >39916_39916_2_INTS1-GET4_INTS1_chr7_1510482_ENST00000389470_GET4_chr7_930565_ENST00000407192_length(amino acids)=2528AA_BP=2356 MWLSGKSQVQKRGAVRYLQAPPVNGEASACPAPPTHLDRTTCARRRPARLPPPWGAAGIRPAPRASRASFWARFPPHCFPSGCSGSRVLE GGEIGFRFRGGRVAAAALRSRWARGDAAAAGSREGRGRMNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQANESKTASTLLKPAPSG LPSERKRDAAAALSSASALTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVL CGAVKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASINFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIE DSLGERIWVDSPHCKTFVDNIQTAFNTRMPPRSVLLQGEAGRVAGDLGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRYEELA ESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTSTCGYKEVRLLAVQKLEMWLQNPKLTRPAQDLLMSVCMNCNTHGSEDMDVISHLIKI RLKPKVLLNHFMLCIRELLSAHKDNLGTTIKLVIFNELSSARNPNNMQVLYTALQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREI IKQTKHEINFQAFCLGLMQERKEPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGIAWDKGEKRNLEVLRSFQNQIAAIQRDAVWW LHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKR AAAVQADDVEVLKVGRTQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMT NNYSYPPCTLTDEETRTEMLNRELQTAQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQYAAHTAPPCACRRDLGPPRRPPP HILDQVKSLNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAVDDAASGEEDDEGESKEQK AKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGETLPALPKAGPAHECLPQGLSLVLSEGSLRDGEE KEPPMEEDVGDTDVLQGYQWLLRDLPRLPLFDSVRSTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQAQHSDLALDVARLVVERST IMSHLFSKLSPSAASDAVLSALLSIFSRYVRRMRQSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRADDSEFQA LLDIWFPEEKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVLRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQFLDQAVAHDPQTLEQ NIMDKSKMPGTCGVGSHTLTEPQPGQAFGAWVRAGVTLLRFADYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPKSSPEQP IGQGRIRVGTQLRVLGPEDDLAGMFLQIFPLSPDPRWQSSSPRPVALALQQALGQELARVVQGSPEVPGITVRVLQALATLLSSPHGGAL VMSMHRSHFLACPLLRQLCQYQRCVPQDTGFSSLFLKVLLQMLQWLDSPGVEGGPLRAQLRMLASQASAGRRLSDVRGGLLRLAEALAFR QDLEVVSSTVRAVIATLRSGEQCSVEPDLISKVLQGLIEVRSPHLEELLTAFFSATADAASPFPACKPVVVVSSLLLQEEEPLAGGKPGA DGGSLEAVRLGPSSGLLVDWLEMLDPEVVSSCPDLQLRLLFSRRKGKGQAQVPSFRPYLLTLFTHQSSWPTLHQCIRVLLGKSREQRFDP SASLDFLWACIHVPRIWQGRDQRTPQAGLGRKRREELVLRVQGPELISLVELILAEAETRSQDGDTAACSLIQARLPLLLSCCCGDDESV RKVTEHLSGCIQQWGDSVLGRRCRDLLLQLYLQRPELRVPVPEVLLHSEGAASSSVCKLDGLIHRFITLLADTSDSRALENRGADASMAC RKLAVAHPLLLLRHLPMIAALLHGRTHLNFQEFRQQNHLSCFLHVLGLLELLQPHVFRSEHQGALWDCLLSFIRLLLNYRKSSRHLAAFI NKFVQFIHKYITYNAPAAISFLQKHADPLHDLSFDNSDLVMLKSLLAGLSLPSRDDRTDRGLDEEGEEESSAGSLPLVSVSLFTPLTAAE MAPYMKRLSRGQTVEDLLEVLSDIDEMSRRRPEILSFFSTNLQRLMSSAEECCRNLAFSLALRSMQNSPSIAAAFLPTFMYCLGSQDFEV VQTALRNLPEYALLCQEQNYCESRYHFLHSADGEGCANMLVEYSTSRGFRSEVDMFVAQAVLQFLCLKNKSSASVVFTTYTQKHPSIEDG PPFVEPLLNFIWFLLLAVDGGKLTVFTVLCEQYQPSLRRDPMYNEYLDRIGQLFFGVPPKQTSSYGGLLGNLLTSLMGSSEQEDGEESPS -------------------------------------------------------------- >39916_39916_3_INTS1-GET4_INTS1_chr7_1510482_ENST00000404767_GET4_chr7_930565_ENST00000265857_length(transcript)=8073nt_BP=6543nt GTGGCCGGGTGGCGGCGGCGGCGCTCCGGTCGCGATGGGCCAGAGGTGACGCCGCAGCCGCCGGGAGCCGCGAGGGACGGGGCAGGATGA ACCGGGCCAAGCCCACCACGGTGCGCCGGCCCAGCGCCGCGGCCAAACCCTCAGGGCACCCTCCCCCAGGAGACTTCATTGCTCTGGGCT CAAAGGGTCAGGCCAATGAATCGAAAACGGCGTCCACCCTGCTGAAGCCAGCCCCTTCCGGCCTGCCTTCTGAGCGCAAGCGGGATGCGG CGGCCGCGTTGTCCAGTGCCTCGGCCCTCACCGGTCTCACCAAACGCCCCAAACTCTCCTCCACACCCCCTCTGAGTGCCCTGGGGCGCC TGGCTGAGGCTGCAGTGGCAGAAAAACGAGCCATTTCTCCGTCGATTAAAGAGCCATCTGTGGTGCCAATTGAAGTGCTGCCCACGGTGC TGCTGGATGAGATCGAGGCGGCCGAGCTGGAGGGCAACGATGACAGGATCGAGGGCGTGCTGTGCGGGGCCGTGAAGCAGCTGAAGGTCA CCCGCGCCAAGCCTGACAGCACCCTCTACCTGAGCCTCATGTACCTGGCCAAGATCAAGCCCAACATCTTCGCCACTGAGGGCGTCATTG AGGCTCTGTGTAGCCTCCTGCGGCGGGACGCCTCCATCAACTTCAAGGCCAAGGGGAACAGCCTGGTGTCTGTGCTGGCCTGTAACCTCC TCATGGCCGCCTACGAGGAGGACGAGAACTGGCCCGAGATCTTTGTCAAGGTGTACATCGAGGACTCCCTGGGGGAGCGGATCTGGGTGG ACAGCCCTCACTGTAAGACGTTTGTGGACAACATCCAGACGGCCTTCAACACCAGAATGCCCCCCAGGAGCGTGCTGCTGCAGGGGGAGG CGGGCCGCGTTGCGGGCGACCTGGGTGCAGGGAGCAGCCCACACCCCTCCCTCACGGAGGAGGAGGACAGCCAGACGGAGTTGCTGATCG CGGAGGAGAAGCTGAGCCCCGAGCAGGAGGGCCAGCTCATGCCCAGGTACGAAGAGCTCGCGGAGAGCGTGGAGGAGTATGTCCTGGACA TGCTGCGGGACCAGCTGAACCGGCGCCAGCCCATCGACAACGTCTCCAGGAACCTCCTGCGGCTCCTCACCTCCACCTGCGGCTATAAGG AGGTGCGGCTGCTGGCGGTGCAGAAGCTGGAGATGTGGCTGCAGAACCCCAAGCTGACCCGGCCGGCCCAGGACCTGCTGATGTCCGTCT GCATGAACTGCAACACGCACGGTTCCGAAGACATGGACGTCATCTCACACCTGATCAAGATCCGCCTCAAGCCCAAGGTCCTCCTCAACC ACTTCATGCTGTGCATCAGGGAGCTGCTGAGCGCGCACAAGGACAACCTGGGCACCACCATCAAGTTGGTGATCTTCAATGAGCTCTCCA GCGCCCGGAACCCGAACAACATGCAGGTCCTCTATACCGCACTGCAGCACAGCTCAGAGCTGGCGCCCAAGTTCCTGGCCATGGTGTTCC AGGACCTGCTGACCAACAAGGACGACTACCTGCGGGCCTCGCGGGCCCTGCTGCGGGAGATCATCAAGCAGACCAAGCACGAGATCAACT TCCAGGCCTTCTGCCTGGGGCTCATGCAGGAGCGCAAGGAGCCGCAGTACCTGGAGATGGAGTTCAAGGAGCGCTTCGTGGTGCACATCA CCGACGTCCTGGCCGTGTCCATGATGCTGGGCATCACAGCGCAGGTGAAGGAGGCCGGCATCGCCTGGGACAAAGGAGAAAAGAGGAACC TGGAAGTGCTCCGCTCATTCCAGAACCAGATTGCCGCCATCCAGCGGGATGCCGTCTGGTGGCTCCACACTGTGGTCCCCTCCATCAGCA AGCTCGCCCCTAAGGACTACGTGCACTGCCTGCACAAGGTGCTGTTCACAGAGCAGCCGGAGACCTACTACAAGTGGGACAACTGGCCAC CCGAGAGTGACCGCAACTTCTTCCTGCGTCTGTGCTCCGAGGTGCCCATTTTGGAGGACACGCTGATGCGCATCCTGGTCATCGGGCTGT CCCGGGAGCTCCCGCTCGGGCCTGCGGACGCCATGGAGCTTGCTGACCACCTGGTGAAGCGGGCGGCTGCCGTGCAGGCGGATGATGTGG AGGTGCTGAAGGTGGGGAGGACCCAGCTGATCGACGCCGTTCTGAATCTGTGCACCTACCATCACCCTGAAAACATCCAGCTCCCACCGG GGTACCAGCCTCCGAACCTCGCCATCTCTACCCTCTACTGGAAGGCCTGGCCCCTCCTGCTGGTCGTCGCCGCATTCAACCCAGAGAACA TCGGCCTGGCTGCGTGGGAGGAGTACCCGACCCTGAAGATGCTCATGGAGATGGTGATGACCAACAACTACTCCTACCCACCGTGCACCC TGACGGATGAGGAGACCCGGACGGAGATGCTGAACCGTGAGCTGCAGACCGCCCAGCGGGAGAAGCAGGAGATCCTGGCCTTCGAGGGGC ACCTGGCGGCCGCGTCCACCAAGCAGACCATCACTGAGAGCAGCAGCCTCCTCCTGTCGCAGCTCACCAGCCTGGACCCCCAGGGGCCCC CCCGGAGGCCTCCCCCTCACATCCTGGATCAAGTGAAAAGCCTCAACCAGTCCCTCCGCCTCGGGCACCTCTTGTGCCGCAGCCGAAACC CTGACTTTCTCCTCCACATCATCCAGCGGCAGGCCTCCTCGCAGTCCATGCCCTGGCTGGCGGACCTGGTACAGTCCAGCGAGGGCTCCC TGGACGTGCTGCCCGTGCAGTGTCTGTGCGAGTTCCTGCTGCACGATGCTGTGGACGATGCTGCTTCCGGGGAGGAGGACGACGAGGGCG AGAGCAAGGAGCAGAAGGCCAAGAAGCGGCAGAGGCAACAGAAGCAGCGGCAGCTGCTGGGCCGCCTGCAGGACCTGCTACTGGGCCCGA AGGCTGATGAGCAGACCACGTGTGAGGTGCTGGACTACTTCTTGCGGCGCCTCGGCTCCTCCCAGGTGGCCTCCCGCGTGCTGGCCATGA AGGGTTTGTCGCTGGTGCTTTCGGAGGGCAGCCTGCGGGACGGGGAGGAGAAGGAGCCCCCCATGGAGGAGGATGTGGGGGACACAGATG TGCTGCAGGGCTATCAGTGGCTGCTGCGGGACCTGCCTCGCCTGCCTCTGTTCGACAGCGTCAGGAGCACCACAGCCCTGGCCCTGCAGC AGGCAATCCACATGGAGACTGATCCCCAGACCATCAGCGCCTACCTGATCTACTTGTCCCAGCACACGCCTGTGGAGGAGCAGGCCCAGC ACAGCGACCTGGCCCTGGACGTGGCCCGGCTGGTCGTGGAGCGCTCCACCATCATGTCCCACCTCTTCTCGAAGCTCTCCCCGAGTGCCG CGTCGGACGCCGTGCTGAGCGCTCTGTTGTCCATCTTCTCACGCTACGTGAGGCGCATGCGGCAGAGCAAGGAGGGCGAGGAGGTCTACA GCTGGTCGGAGTCTCAGGACCAGGTCTTCCTACGCTGGAGCAGCGGGGAGACAGCCACCATGCACATCCTCGTGGTCCATGCCATGGTGA TCCTGCTGACGCTGGGCCCGCCTCGAGCCGACGACAGCGAGTTCCAGGCGCTGCTGGACATCTGGTTTCCGGAGGAGAAGCCACTGCCCA CCGCCTTCCTGGTGGACACATCGGAGGAGGCGCTGCTGCTTCCTGACTGGCTGAAGCTGCGCATGATCCGTTCTGAGGTGCTCCGCCTGG TGGACGCCGCCCTGCAGGACCTGGAGCCGCAGCAGCTGCTGCTGTTCGTGCAGTCGTTTGGCATCCCCGTGTCCAGCATGAGCAAACTCC TCCAGTTCCTGGACCAGGCAGTGGCCCACGACCCCCAGACTCTGGAGCAGAACATCATGGACAAGAATTACATGGCCCACCTGGTGGAGG TCCAGCATGAGCGCGGCGCCTCCGGAGGCCAGACTTTCCACTCCTTGCTCACAGCCTCCCTGCCGCCCCGCCGAGACAGCACAGAGGCAC CCAAACCAAAGAGCAGCCCAGAGCAGCCCATAGGCCAGGGCCGGATTCGGGTGGGGACCCAGCTCCGGGTGCTGGGCCCTGAGGACGACC TGGCTGGCATGTTCCTCCAGATTTTCCCGCTCAGCCCGGACCCTCGGTGGCAGAGCTCCAGTCCCCGCCCCGTGGCCCTCGCCCTGCAGC AGGCCCTGGGCCAGGAGCTGGCCCGCGTCGTCCAGGGCAGCCCCGAGGTGCCGGGCATCACGGTGCGTGTCCTGCAGGCCCTCGCCACCC TGCTCAGCTCCCCACACGGCGGTGCCCTGGTGATGTCCATGCACCGTAGCCACTTCCTGGCCTGCCCGCTGCTGCGCCAGCTCTGCCAGT ACCAGCGCTGTGTGCCACAGGACACCGGCTTCTCCTCGCTCTTCCTGAAGGTGCTCCTGCAGATGCTGCAGTGGCTGGACAGCCCTGGCG TGGAGGGCGGGCCCCTGCGGGCACAGCTCAGGATGCTTGCCAGCCAGGCCTCAGCCGGGCGCAGGCTCAGTGATGTGCGAGGGGGGCTCC TGCGCCTGGCCGAGGCCCTGGCCTTCCGTCAGGACCTGGAGGTGGTCAGCTCCACCGTCCGTGCCGTCATCGCCACCCTGAGGTCTGGGG AGCAGTGCAGCGTGGAGCCGGACCTGATCAGCAAAGTCCTCCAGGGGCTGATCGAGGTGAGGTCCCCCCACCTGGAGGAGCTGCTGACTG CATTCTTCTCTGCCACTGCGGATGCTGCCTCCCCGTTTCCAGCCTGTAAGCCCGTTGTGGTGGTGAGCTCCCTGCTGCTGCAGGAGGAGG AGCCCCTGGCTGGGGGGAAGCCGGGTGCGGACGGTGGCAGCCTGGAGGCCGTGCGGCTGGGGCCCTCGTCAGGCCTCCTAGTGGACTGGC TGGAAATGCTGGACCCCGAGGTGGTCAGCAGCTGCCCCGACCTGCAGCTCAGGCTGCTCTTCTCCCGGAGGAAGGGCAAAGGTCAGGCCC AGGTGCCCTCGTTCCGTCCCTACCTCCTGACCCTCTTCACGCATCAGTCCAGCTGGCCCACACTGCACCAGTGCATCCGAGTCCTGCTGG GCAAGAGCCGGGAACAGAGGTTCGACCCCTCTGCCTCTCTGGACTTCCTCTGGGCCTGCATCCATGTTCCTCGCATCTGGCAGGGGCGGG ACCAGCGCACCCCGCAGAAGCGGCGGGAGGAGCTGGTGCTGCGGGTCCAGGGCCCGGAGCTCATCAGCCTGGTGGAGCTGATCCTGGCCG AGGCGGAGACGCGGAGCCAGGACGGGGACACAGCCGCCTGCAGCCTCATCCAGGCCCGGCTGCCCCTGCTGCTCAGCTGCTGCTGTGGGG ACGATGAGAGTGTCAGGAAGGTGACGGAGCACCTGTCAGGCTGCATCCAGCAGTGGGGAGACAGCGTGCTGGGCAGGCGCTGCCGAGACC TTCTCCTGCAGCTCTACCTACAGCGGCCGGAGCTGCGGGTGCCCGTGCCTGAGGTCCTACTGCACAGCGAAGGGGCTGCCAGCAGCAGCG TCTGCAAGCTGGACGGACTCATCCACCGCTTCATCACGCTCCTTGCGGACACCAGCGACTCCCGGGCGTTGGAGAACCGAGGGGCGGATG CCAGCATGGCCTGCCGGAAGCTGGCGGTGGCGCACCCGCTGCTGCTGCTCAGGCACCTGCCCATGATCGCGGCGCTCCTGCACGGCCGCA CCCACCTCAACTTCCAGGAGTTCCGGCAGCAGAACCACCTGAGCTGCTTCCTGCACGTGCTGGGCCTGCTGGAGCTGCTGCAGCCGCACG TGTTCCGCAGCGAGCACCAGGGGGCGCTGTGGGACTGCCTTCTGTCCTTCATCCGCCTGCTGCTGAATTACAGGAAGTCCTCCCGCCATC TGGCTGCCTTCATCAACAAGTTTGTGCAGTTCATCCATAAGTACATTACCTACAATGCCCCAGCAGCCATCTCCTTCCTGCAGAAGCACG CCGACCCGCTCCACGACCTGTCCTTCGACAACAGTGACCTGGTGATGCTGAAATCCCTCCTTGCAGGGCTCAGCCTGCCCAGCAGGGACG ACAGGACCGACCGAGGCCTGGACGAAGAGGGCGAGGAGGAGAGCTCAGCCGGCTCCTTGCCCCTGGTCAGCGTCTCCCTGTTCACCCCTC TGACCGCGGCCGAGATGGCCCCCTACATGAAACGGCTTTCCCGGGGCCAAACGGTGGAGGATCTGCTGGAGGTTCTGAGTGACATAGACG AGATGTCCCGGCGGAGACCCGAGATCCTGAGCTTCTTCTCGACCAACCTGCAGCGGCTGATGAGCTCGGCCGAGGAGTGTTGCCGCAACC TCGCCTTCAGCCTGGCCCTGCGCTCCATGCAGAACAGCCCCAGCATTGCAGCCGCTTTCCTGCCCACGTTCATGTACTGCCTGGGCAGCC AGGACTTTGAGGTGGTGCAGACGGCCCTCCGGAACCTGCCTGAGTACGCTCTCCTGTGCCAAGAACAAAACTATTGTGAGTCGAGGTATC ATTTTCTGCACTCAGCGGACGGGGAGGGCTGTGCCAACATGCTGGTGGAGTATTCCACGTCCCGCGGCTTCCGCAGCGAGGTGGACATGT TCGTGGCCCAGGCCGTGCTACAGTTTCTCTGTTTAAAAAACAAAAGTAGCGCATCGGTGGTCTTCACGACGTACACCCAGAAGCACCCGT CCATCGAGGACGGGCCTCCGTTTGTGGAGCCGCTGCTTAACTTCATCTGGTTCCTGCTGCTGGCTGTGGACGGTGGGAAGCTGACGGTGT TCACTGTGCTGTGTGAGCAGTACCAGCCATCCCTCCGGCGGGACCCCATGTACAACGAGTACCTCGACCGCATAGGACAGCTGTTCTTCG GCGTCCCGCCCAAGCAGACGTCTTCCTACGGGGGCCTGCTCGGGAACCTTCTGACCAGCCTCATGGGCTCCTCAGAGCAGGAGGATGGGG AGGAGAGCCCCAGCGACGGCAGCCCCATCGAGCTGGACTGAACTGGCCAGGCCACGTGGAGACACCACGGTCGACGACGGCTGGAGGGAC GTTTCAGAGGCGAGTCCTGGGTGGCTCCTCGCCTTGGGGGCTCCTGGCCCTGAGGCTGGCGGTGGCCGCATGCCGGCGCGTGTCTGTTTC TGTGCGGCGGCTCAGGGTGGCGCGGCTGCTGCTCACTGTGCTGCTGGGACCCAAGAGTGGGGCGTCGCCCCTGCTGGCCGCCGCGTCCCC CGAGATTGACCCACAATAAAGCACAGGCCTTACCGCGGCGTCACCCTCTCCCACTCCTTTGTTCTGGGTCCTTTCGGGAGGGCTGATGGG CAGCACAGGAGGCCCGTCCTCGGGGGGCTGCGCACATCACGCTCCTTGCCGGGCGTCCGGCACAGCTGCGGTCACCAAAGCAGGTGCTGG CCCTCGGACCTGAGAGCCCAGCCAGGGCCCATGTGGTCTGCAAATGGGAGCGGCTGTTTTTGAACACGGGGTCATTCTGCAGTCAGGACG AACCGGTCCCCGTCGCAGACGGAGTGCACGTGCCCTGCGCCACATCCTCACGCTCGGTGGAGGGACGCGTGCGGCGGGACGGTGCCTACG GGTACTTGCAGCTGTGTCCCATGTGGCATCCCAGAGCTGCGCCCTGCTGGTCTCTGTGAGCGCCACGCTGCTGTGCTGGAAATGCCGCTT TAAAAAGGGATACCGTGGGACTCTGCCCGTCTCTTTCATAACGCAATATTTATTTGTATTGGGTGATGATTGATTCTTTCGACCTAACAT TTTGGGTTTTAACCAAATAACCGGTCCAGGAGTGAGCAGCTCCGTTCTGTCAGATGCTACTCCAAATGTTACCAGAACGATGACAAAAGG GGAGACGCTCTATTTTTTCACAGTTAAATGACAGTTGTAGATTGATACGCAGTTGTGCATGGGAAGGGGAAACGCACAGCTTTATTTACT >39916_39916_3_INTS1-GET4_INTS1_chr7_1510482_ENST00000404767_GET4_chr7_930565_ENST00000265857_length(amino acids)=2324AA_BP=2152 MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQANESKTASTLLKPAPSGLPSERKRDAAAALSSASALTGLTKRPKLSSTPPLSALG RLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGV IEALCSLLRRDASINFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCKTFVDNIQTAFNTRMPPRSVLLQG EAGRVAGDLGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRYEELAESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTSTCGY KEVRLLAVQKLEMWLQNPKLTRPAQDLLMSVCMNCNTHGSEDMDVISHLIKIRLKPKVLLNHFMLCIRELLSAHKDNLGTTIKLVIFNEL SSARNPNNMQVLYTALQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLEMEFKERFVVH ITDVLAVSMMLGITAQVKEAGIAWDKGEKRNLEVLRSFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNW PPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVGRTQLIDAVLNLCTYHHPENIQLP PGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMLNRELQTAQREKQEILAFE GHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKSLNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEG SLDVLPVQCLCEFLLHDAVDDAASGEEDDEGESKEQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLA MKGLSLVLSEGSLRDGEEKEPPMEEDVGDTDVLQGYQWLLRDLPRLPLFDSVRSTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQA QHSDLALDVARLVVERSTIMSHLFSKLSPSAASDAVLSALLSIFSRYVRRMRQSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAM VILLTLGPPRADDSEFQALLDIWFPEEKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVLRLVDAALQDLEPQQLLLFVQSFGIPVSSMSK LLQFLDQAVAHDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPKSSPEQPIGQGRIRVGTQLRVLGPED DLAGMFLQIFPLSPDPRWQSSSPRPVALALQQALGQELARVVQGSPEVPGITVRVLQALATLLSSPHGGALVMSMHRSHFLACPLLRQLC QYQRCVPQDTGFSSLFLKVLLQMLQWLDSPGVEGGPLRAQLRMLASQASAGRRLSDVRGGLLRLAEALAFRQDLEVVSSTVRAVIATLRS GEQCSVEPDLISKVLQGLIEVRSPHLEELLTAFFSATADAASPFPACKPVVVVSSLLLQEEEPLAGGKPGADGGSLEAVRLGPSSGLLVD WLEMLDPEVVSSCPDLQLRLLFSRRKGKGQAQVPSFRPYLLTLFTHQSSWPTLHQCIRVLLGKSREQRFDPSASLDFLWACIHVPRIWQG RDQRTPQKRREELVLRVQGPELISLVELILAEAETRSQDGDTAACSLIQARLPLLLSCCCGDDESVRKVTEHLSGCIQQWGDSVLGRRCR DLLLQLYLQRPELRVPVPEVLLHSEGAASSSVCKLDGLIHRFITLLADTSDSRALENRGADASMACRKLAVAHPLLLLRHLPMIAALLHG RTHLNFQEFRQQNHLSCFLHVLGLLELLQPHVFRSEHQGALWDCLLSFIRLLLNYRKSSRHLAAFINKFVQFIHKYITYNAPAAISFLQK HADPLHDLSFDNSDLVMLKSLLAGLSLPSRDDRTDRGLDEEGEEESSAGSLPLVSVSLFTPLTAAEMAPYMKRLSRGQTVEDLLEVLSDI DEMSRRRPEILSFFSTNLQRLMSSAEECCRNLAFSLALRSMQNSPSIAAAFLPTFMYCLGSQDFEVVQTALRNLPEYALLCQEQNYCESR YHFLHSADGEGCANMLVEYSTSRGFRSEVDMFVAQAVLQFLCLKNKSSASVVFTTYTQKHPSIEDGPPFVEPLLNFIWFLLLAVDGGKLT -------------------------------------------------------------- >39916_39916_4_INTS1-GET4_INTS1_chr7_1510482_ENST00000404767_GET4_chr7_930565_ENST00000407192_length(transcript)=8075nt_BP=6543nt GTGGCCGGGTGGCGGCGGCGGCGCTCCGGTCGCGATGGGCCAGAGGTGACGCCGCAGCCGCCGGGAGCCGCGAGGGACGGGGCAGGATGA ACCGGGCCAAGCCCACCACGGTGCGCCGGCCCAGCGCCGCGGCCAAACCCTCAGGGCACCCTCCCCCAGGAGACTTCATTGCTCTGGGCT CAAAGGGTCAGGCCAATGAATCGAAAACGGCGTCCACCCTGCTGAAGCCAGCCCCTTCCGGCCTGCCTTCTGAGCGCAAGCGGGATGCGG CGGCCGCGTTGTCCAGTGCCTCGGCCCTCACCGGTCTCACCAAACGCCCCAAACTCTCCTCCACACCCCCTCTGAGTGCCCTGGGGCGCC TGGCTGAGGCTGCAGTGGCAGAAAAACGAGCCATTTCTCCGTCGATTAAAGAGCCATCTGTGGTGCCAATTGAAGTGCTGCCCACGGTGC TGCTGGATGAGATCGAGGCGGCCGAGCTGGAGGGCAACGATGACAGGATCGAGGGCGTGCTGTGCGGGGCCGTGAAGCAGCTGAAGGTCA CCCGCGCCAAGCCTGACAGCACCCTCTACCTGAGCCTCATGTACCTGGCCAAGATCAAGCCCAACATCTTCGCCACTGAGGGCGTCATTG AGGCTCTGTGTAGCCTCCTGCGGCGGGACGCCTCCATCAACTTCAAGGCCAAGGGGAACAGCCTGGTGTCTGTGCTGGCCTGTAACCTCC TCATGGCCGCCTACGAGGAGGACGAGAACTGGCCCGAGATCTTTGTCAAGGTGTACATCGAGGACTCCCTGGGGGAGCGGATCTGGGTGG ACAGCCCTCACTGTAAGACGTTTGTGGACAACATCCAGACGGCCTTCAACACCAGAATGCCCCCCAGGAGCGTGCTGCTGCAGGGGGAGG CGGGCCGCGTTGCGGGCGACCTGGGTGCAGGGAGCAGCCCACACCCCTCCCTCACGGAGGAGGAGGACAGCCAGACGGAGTTGCTGATCG CGGAGGAGAAGCTGAGCCCCGAGCAGGAGGGCCAGCTCATGCCCAGGTACGAAGAGCTCGCGGAGAGCGTGGAGGAGTATGTCCTGGACA TGCTGCGGGACCAGCTGAACCGGCGCCAGCCCATCGACAACGTCTCCAGGAACCTCCTGCGGCTCCTCACCTCCACCTGCGGCTATAAGG AGGTGCGGCTGCTGGCGGTGCAGAAGCTGGAGATGTGGCTGCAGAACCCCAAGCTGACCCGGCCGGCCCAGGACCTGCTGATGTCCGTCT GCATGAACTGCAACACGCACGGTTCCGAAGACATGGACGTCATCTCACACCTGATCAAGATCCGCCTCAAGCCCAAGGTCCTCCTCAACC ACTTCATGCTGTGCATCAGGGAGCTGCTGAGCGCGCACAAGGACAACCTGGGCACCACCATCAAGTTGGTGATCTTCAATGAGCTCTCCA GCGCCCGGAACCCGAACAACATGCAGGTCCTCTATACCGCACTGCAGCACAGCTCAGAGCTGGCGCCCAAGTTCCTGGCCATGGTGTTCC AGGACCTGCTGACCAACAAGGACGACTACCTGCGGGCCTCGCGGGCCCTGCTGCGGGAGATCATCAAGCAGACCAAGCACGAGATCAACT TCCAGGCCTTCTGCCTGGGGCTCATGCAGGAGCGCAAGGAGCCGCAGTACCTGGAGATGGAGTTCAAGGAGCGCTTCGTGGTGCACATCA CCGACGTCCTGGCCGTGTCCATGATGCTGGGCATCACAGCGCAGGTGAAGGAGGCCGGCATCGCCTGGGACAAAGGAGAAAAGAGGAACC TGGAAGTGCTCCGCTCATTCCAGAACCAGATTGCCGCCATCCAGCGGGATGCCGTCTGGTGGCTCCACACTGTGGTCCCCTCCATCAGCA AGCTCGCCCCTAAGGACTACGTGCACTGCCTGCACAAGGTGCTGTTCACAGAGCAGCCGGAGACCTACTACAAGTGGGACAACTGGCCAC CCGAGAGTGACCGCAACTTCTTCCTGCGTCTGTGCTCCGAGGTGCCCATTTTGGAGGACACGCTGATGCGCATCCTGGTCATCGGGCTGT CCCGGGAGCTCCCGCTCGGGCCTGCGGACGCCATGGAGCTTGCTGACCACCTGGTGAAGCGGGCGGCTGCCGTGCAGGCGGATGATGTGG AGGTGCTGAAGGTGGGGAGGACCCAGCTGATCGACGCCGTTCTGAATCTGTGCACCTACCATCACCCTGAAAACATCCAGCTCCCACCGG GGTACCAGCCTCCGAACCTCGCCATCTCTACCCTCTACTGGAAGGCCTGGCCCCTCCTGCTGGTCGTCGCCGCATTCAACCCAGAGAACA TCGGCCTGGCTGCGTGGGAGGAGTACCCGACCCTGAAGATGCTCATGGAGATGGTGATGACCAACAACTACTCCTACCCACCGTGCACCC TGACGGATGAGGAGACCCGGACGGAGATGCTGAACCGTGAGCTGCAGACCGCCCAGCGGGAGAAGCAGGAGATCCTGGCCTTCGAGGGGC ACCTGGCGGCCGCGTCCACCAAGCAGACCATCACTGAGAGCAGCAGCCTCCTCCTGTCGCAGCTCACCAGCCTGGACCCCCAGGGGCCCC CCCGGAGGCCTCCCCCTCACATCCTGGATCAAGTGAAAAGCCTCAACCAGTCCCTCCGCCTCGGGCACCTCTTGTGCCGCAGCCGAAACC CTGACTTTCTCCTCCACATCATCCAGCGGCAGGCCTCCTCGCAGTCCATGCCCTGGCTGGCGGACCTGGTACAGTCCAGCGAGGGCTCCC TGGACGTGCTGCCCGTGCAGTGTCTGTGCGAGTTCCTGCTGCACGATGCTGTGGACGATGCTGCTTCCGGGGAGGAGGACGACGAGGGCG AGAGCAAGGAGCAGAAGGCCAAGAAGCGGCAGAGGCAACAGAAGCAGCGGCAGCTGCTGGGCCGCCTGCAGGACCTGCTACTGGGCCCGA AGGCTGATGAGCAGACCACGTGTGAGGTGCTGGACTACTTCTTGCGGCGCCTCGGCTCCTCCCAGGTGGCCTCCCGCGTGCTGGCCATGA AGGGTTTGTCGCTGGTGCTTTCGGAGGGCAGCCTGCGGGACGGGGAGGAGAAGGAGCCCCCCATGGAGGAGGATGTGGGGGACACAGATG TGCTGCAGGGCTATCAGTGGCTGCTGCGGGACCTGCCTCGCCTGCCTCTGTTCGACAGCGTCAGGAGCACCACAGCCCTGGCCCTGCAGC AGGCAATCCACATGGAGACTGATCCCCAGACCATCAGCGCCTACCTGATCTACTTGTCCCAGCACACGCCTGTGGAGGAGCAGGCCCAGC ACAGCGACCTGGCCCTGGACGTGGCCCGGCTGGTCGTGGAGCGCTCCACCATCATGTCCCACCTCTTCTCGAAGCTCTCCCCGAGTGCCG CGTCGGACGCCGTGCTGAGCGCTCTGTTGTCCATCTTCTCACGCTACGTGAGGCGCATGCGGCAGAGCAAGGAGGGCGAGGAGGTCTACA GCTGGTCGGAGTCTCAGGACCAGGTCTTCCTACGCTGGAGCAGCGGGGAGACAGCCACCATGCACATCCTCGTGGTCCATGCCATGGTGA TCCTGCTGACGCTGGGCCCGCCTCGAGCCGACGACAGCGAGTTCCAGGCGCTGCTGGACATCTGGTTTCCGGAGGAGAAGCCACTGCCCA CCGCCTTCCTGGTGGACACATCGGAGGAGGCGCTGCTGCTTCCTGACTGGCTGAAGCTGCGCATGATCCGTTCTGAGGTGCTCCGCCTGG TGGACGCCGCCCTGCAGGACCTGGAGCCGCAGCAGCTGCTGCTGTTCGTGCAGTCGTTTGGCATCCCCGTGTCCAGCATGAGCAAACTCC TCCAGTTCCTGGACCAGGCAGTGGCCCACGACCCCCAGACTCTGGAGCAGAACATCATGGACAAGAATTACATGGCCCACCTGGTGGAGG TCCAGCATGAGCGCGGCGCCTCCGGAGGCCAGACTTTCCACTCCTTGCTCACAGCCTCCCTGCCGCCCCGCCGAGACAGCACAGAGGCAC CCAAACCAAAGAGCAGCCCAGAGCAGCCCATAGGCCAGGGCCGGATTCGGGTGGGGACCCAGCTCCGGGTGCTGGGCCCTGAGGACGACC TGGCTGGCATGTTCCTCCAGATTTTCCCGCTCAGCCCGGACCCTCGGTGGCAGAGCTCCAGTCCCCGCCCCGTGGCCCTCGCCCTGCAGC AGGCCCTGGGCCAGGAGCTGGCCCGCGTCGTCCAGGGCAGCCCCGAGGTGCCGGGCATCACGGTGCGTGTCCTGCAGGCCCTCGCCACCC TGCTCAGCTCCCCACACGGCGGTGCCCTGGTGATGTCCATGCACCGTAGCCACTTCCTGGCCTGCCCGCTGCTGCGCCAGCTCTGCCAGT ACCAGCGCTGTGTGCCACAGGACACCGGCTTCTCCTCGCTCTTCCTGAAGGTGCTCCTGCAGATGCTGCAGTGGCTGGACAGCCCTGGCG TGGAGGGCGGGCCCCTGCGGGCACAGCTCAGGATGCTTGCCAGCCAGGCCTCAGCCGGGCGCAGGCTCAGTGATGTGCGAGGGGGGCTCC TGCGCCTGGCCGAGGCCCTGGCCTTCCGTCAGGACCTGGAGGTGGTCAGCTCCACCGTCCGTGCCGTCATCGCCACCCTGAGGTCTGGGG AGCAGTGCAGCGTGGAGCCGGACCTGATCAGCAAAGTCCTCCAGGGGCTGATCGAGGTGAGGTCCCCCCACCTGGAGGAGCTGCTGACTG CATTCTTCTCTGCCACTGCGGATGCTGCCTCCCCGTTTCCAGCCTGTAAGCCCGTTGTGGTGGTGAGCTCCCTGCTGCTGCAGGAGGAGG AGCCCCTGGCTGGGGGGAAGCCGGGTGCGGACGGTGGCAGCCTGGAGGCCGTGCGGCTGGGGCCCTCGTCAGGCCTCCTAGTGGACTGGC TGGAAATGCTGGACCCCGAGGTGGTCAGCAGCTGCCCCGACCTGCAGCTCAGGCTGCTCTTCTCCCGGAGGAAGGGCAAAGGTCAGGCCC AGGTGCCCTCGTTCCGTCCCTACCTCCTGACCCTCTTCACGCATCAGTCCAGCTGGCCCACACTGCACCAGTGCATCCGAGTCCTGCTGG GCAAGAGCCGGGAACAGAGGTTCGACCCCTCTGCCTCTCTGGACTTCCTCTGGGCCTGCATCCATGTTCCTCGCATCTGGCAGGGGCGGG ACCAGCGCACCCCGCAGAAGCGGCGGGAGGAGCTGGTGCTGCGGGTCCAGGGCCCGGAGCTCATCAGCCTGGTGGAGCTGATCCTGGCCG AGGCGGAGACGCGGAGCCAGGACGGGGACACAGCCGCCTGCAGCCTCATCCAGGCCCGGCTGCCCCTGCTGCTCAGCTGCTGCTGTGGGG ACGATGAGAGTGTCAGGAAGGTGACGGAGCACCTGTCAGGCTGCATCCAGCAGTGGGGAGACAGCGTGCTGGGCAGGCGCTGCCGAGACC TTCTCCTGCAGCTCTACCTACAGCGGCCGGAGCTGCGGGTGCCCGTGCCTGAGGTCCTACTGCACAGCGAAGGGGCTGCCAGCAGCAGCG TCTGCAAGCTGGACGGACTCATCCACCGCTTCATCACGCTCCTTGCGGACACCAGCGACTCCCGGGCGTTGGAGAACCGAGGGGCGGATG CCAGCATGGCCTGCCGGAAGCTGGCGGTGGCGCACCCGCTGCTGCTGCTCAGGCACCTGCCCATGATCGCGGCGCTCCTGCACGGCCGCA CCCACCTCAACTTCCAGGAGTTCCGGCAGCAGAACCACCTGAGCTGCTTCCTGCACGTGCTGGGCCTGCTGGAGCTGCTGCAGCCGCACG TGTTCCGCAGCGAGCACCAGGGGGCGCTGTGGGACTGCCTTCTGTCCTTCATCCGCCTGCTGCTGAATTACAGGAAGTCCTCCCGCCATC TGGCTGCCTTCATCAACAAGTTTGTGCAGTTCATCCATAAGTACATTACCTACAATGCCCCAGCAGCCATCTCCTTCCTGCAGAAGCACG CCGACCCGCTCCACGACCTGTCCTTCGACAACAGTGACCTGGTGATGCTGAAATCCCTCCTTGCAGGGCTCAGCCTGCCCAGCAGGGACG ACAGGACCGACCGAGGCCTGGACGAAGAGGGCGAGGAGGAGAGCTCAGCCGGCTCCTTGCCCCTGGTCAGCGTCTCCCTGTTCACCCCTC TGACCGCGGCCGAGATGGCCCCCTACATGAAACGGCTTTCCCGGGGCCAAACGGTGGAGGATCTGCTGGAGGTTCTGAGTGACATAGACG AGATGTCCCGGCGGAGACCCGAGATCCTGAGCTTCTTCTCGACCAACCTGCAGCGGCTGATGAGCTCGGCCGAGGAGTGTTGCCGCAACC TCGCCTTCAGCCTGGCCCTGCGCTCCATGCAGAACAGCCCCAGCATTGCAGCCGCTTTCCTGCCCACGTTCATGTACTGCCTGGGCAGCC AGGACTTTGAGGTGGTGCAGACGGCCCTCCGGAACCTGCCTGAGTACGCTCTCCTGTGCCAAGAACAAAACTATTGTGAGTCGAGGTATC ATTTTCTGCACTCAGCGGACGGGGAGGGCTGTGCCAACATGCTGGTGGAGTATTCCACGTCCCGCGGCTTCCGCAGCGAGGTGGACATGT TCGTGGCCCAGGCCGTGCTACAGTTTCTCTGTTTAAAAAACAAAAGTAGCGCATCGGTGGTCTTCACGACGTACACCCAGAAGCACCCGT CCATCGAGGACGGGCCTCCGTTTGTGGAGCCGCTGCTTAACTTCATCTGGTTCCTGCTGCTGGCTGTGGACGGTGGGAAGCTGACGGTGT TCACTGTGCTGTGTGAGCAGTACCAGCCATCCCTCCGGCGGGACCCCATGTACAACGAGTACCTCGACCGCATAGGACAGCTGTTCTTCG GCGTCCCGCCCAAGCAGACGTCTTCCTACGGGGGCCTGCTCGGGAACCTTCTGACCAGCCTCATGGGCTCCTCAGAGCAGGAGGATGGGG AGGAGAGCCCCAGCGACGGCAGCCCCATCGAGCTGGACTGAACTGGCCAGGCCACGTGGAGACACCACGGTCGACGACGGCTGGAGGGAC GTTTCAGAGGCGAGTCCTGGGTGGCTCCTCGCCTTGGGGGCTCCTGGCCCTGAGGCTGGCGGTGGCCGCATGCCGGCGCGTGTCTGTTTC TGTGCGGCGGCTCAGGGTGGCGCGGCTGCTGCTCACTGTGCTGCTGGGACCCAAGAGTGGGGCGTCGCCCCTGCTGGCCGCCGCGTCCCC CGAGATTGACCCACAATAAAGCACAGGCCTTACCGCGGCGTCACCCTCTCCCACTCCTTTGTTCTGGGTCCTTTCGGGAGGGCTGATGGG CAGCACAGGAGGCCCGTCCTCGGGGGGCTGCGCACATCACGCTCCTTGCCGGGCGTCCGGCACAGCTGCGGTCACCAAAGCAGGTGCTGG CCCTCGGACCTGAGAGCCCAGCCAGGGCCCATGTGGTCTGCAAATGGGAGCGGCTGTTTTTGAACACGGGGTCATTCTGCAGTCAGGACG AACCGGTCCCCGTCGCAGACGGAGTGCACGTGCCCTGCGCCACATCCTCACGCTCGGTGGAGGGACGCGTGCGGCGGGACGGTGCCTACG GGTACTTGCAGCTGTGTCCCATGTGGCATCCCAGAGCTGCGCCCTGCTGGTCTCTGTGAGCGCCACGCTGCTGTGCTGGAAATGCCGCTT TAAAAAGGGATACCGTGGGACTCTGCCCGTCTCTTTCATAACGCAATATTTATTTGTATTGGGTGATGATTGATTCTTTCGACCTAACAT TTTGGGTTTTAACCAAATAACCGGTCCAGGAGTGAGCAGCTCCGTTCTGTCAGATGCTACTCCAAATGTTACCAGAACGATGACAAAAGG GGAGACGCTCTATTTTTTCACAGTTAAATGACAGTTGTAGATTGATACGCAGTTGTGCATGGGAAGGGGAAACGCACAGCTTTATTTACT >39916_39916_4_INTS1-GET4_INTS1_chr7_1510482_ENST00000404767_GET4_chr7_930565_ENST00000407192_length(amino acids)=2324AA_BP=2152 MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQANESKTASTLLKPAPSGLPSERKRDAAAALSSASALTGLTKRPKLSSTPPLSALG RLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGV IEALCSLLRRDASINFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCKTFVDNIQTAFNTRMPPRSVLLQG EAGRVAGDLGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRYEELAESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTSTCGY KEVRLLAVQKLEMWLQNPKLTRPAQDLLMSVCMNCNTHGSEDMDVISHLIKIRLKPKVLLNHFMLCIRELLSAHKDNLGTTIKLVIFNEL SSARNPNNMQVLYTALQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLEMEFKERFVVH ITDVLAVSMMLGITAQVKEAGIAWDKGEKRNLEVLRSFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNW PPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVGRTQLIDAVLNLCTYHHPENIQLP PGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMLNRELQTAQREKQEILAFE GHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKSLNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEG SLDVLPVQCLCEFLLHDAVDDAASGEEDDEGESKEQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLA MKGLSLVLSEGSLRDGEEKEPPMEEDVGDTDVLQGYQWLLRDLPRLPLFDSVRSTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQA QHSDLALDVARLVVERSTIMSHLFSKLSPSAASDAVLSALLSIFSRYVRRMRQSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAM VILLTLGPPRADDSEFQALLDIWFPEEKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVLRLVDAALQDLEPQQLLLFVQSFGIPVSSMSK LLQFLDQAVAHDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPKSSPEQPIGQGRIRVGTQLRVLGPED DLAGMFLQIFPLSPDPRWQSSSPRPVALALQQALGQELARVVQGSPEVPGITVRVLQALATLLSSPHGGALVMSMHRSHFLACPLLRQLC QYQRCVPQDTGFSSLFLKVLLQMLQWLDSPGVEGGPLRAQLRMLASQASAGRRLSDVRGGLLRLAEALAFRQDLEVVSSTVRAVIATLRS GEQCSVEPDLISKVLQGLIEVRSPHLEELLTAFFSATADAASPFPACKPVVVVSSLLLQEEEPLAGGKPGADGGSLEAVRLGPSSGLLVD WLEMLDPEVVSSCPDLQLRLLFSRRKGKGQAQVPSFRPYLLTLFTHQSSWPTLHQCIRVLLGKSREQRFDPSASLDFLWACIHVPRIWQG RDQRTPQKRREELVLRVQGPELISLVELILAEAETRSQDGDTAACSLIQARLPLLLSCCCGDDESVRKVTEHLSGCIQQWGDSVLGRRCR DLLLQLYLQRPELRVPVPEVLLHSEGAASSSVCKLDGLIHRFITLLADTSDSRALENRGADASMACRKLAVAHPLLLLRHLPMIAALLHG RTHLNFQEFRQQNHLSCFLHVLGLLELLQPHVFRSEHQGALWDCLLSFIRLLLNYRKSSRHLAAFINKFVQFIHKYITYNAPAAISFLQK HADPLHDLSFDNSDLVMLKSLLAGLSLPSRDDRTDRGLDEEGEEESSAGSLPLVSVSLFTPLTAAEMAPYMKRLSRGQTVEDLLEVLSDI DEMSRRRPEILSFFSTNLQRLMSSAEECCRNLAFSLALRSMQNSPSIAAAFLPTFMYCLGSQDFEVVQTALRNLPEYALLCQEQNYCESR YHFLHSADGEGCANMLVEYSTSRGFRSEVDMFVAQAVLQFLCLKNKSSASVVFTTYTQKHPSIEDGPPFVEPLLNFIWFLLLAVDGGKLT -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for INTS1-GET4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for INTS1-GET4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for INTS1-GET4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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