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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:INTS4-ALG8 (FusionGDB2 ID:39941)

Fusion Gene Summary for INTS4-ALG8

check button Fusion gene summary
Fusion gene informationFusion gene name: INTS4-ALG8
Fusion gene ID: 39941
HgeneTgene
Gene symbol

INTS4

ALG8

Gene ID

92105

79053

Gene nameintegrator complex subunit 4ALG8 alpha-1,3-glucosyltransferase
SynonymsINT4|MST093CDG1H|PCLD3
Cytomap

11q14.1

11q14.1

Type of geneprotein-codingprotein-coding
Descriptionintegrator complex subunit 4MSTP093probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferaseHUSSY-02asparagine-linked glycosylation 8 alpha-13-glucosyltransferase-like proteinasparagine-linked glycosylation 8 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase)asp
Modification date2020031320200313
UniProtAcc

Q96HW7

Q9BVK2

Ensembl transtripts involved in fusion geneENST00000529807, ENST00000534064, 
ENST00000535943, ENST00000525931, 
ENST00000527522, 		ENST00000532552, 
ENST00000299626, ENST00000376156, 
Fusion gene scores* DoF score21 X 14 X 10=29406 X 6 X 8=288
# samples 2910
** MAII scorelog2(29/2940*10)=-3.34169134970879
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/288*10)=-1.52606881166759
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: INTS4 [Title/Abstract] AND ALG8 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointINTS4(77649697)-ALG8(77820627), # samples:2
Anticipated loss of major functional domain due to fusion event.INTS4-ALG8 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
INTS4-ALG8 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
INTS4-ALG8 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneINTS4

GO:0016180

snRNA processing

16239144


check buttonFusion gene breakpoints across INTS4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ALG8 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-1436INTS4chr11

77602364

-ALG8chr11

77817992

-
ChimerDB4SKCMTCGA-FR-A7U8-06AINTS4chr11

77649697

-ALG8chr11

77817958

-
ChimerDB4SKCMTCGA-FR-A7U8-06AINTS4chr11

77649697

-ALG8chr11

77820627

-


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Fusion Gene ORF analysis for INTS4-ALG8

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000529807ENST00000532552INTS4chr11

77649697

-ALG8chr11

77817958

-
5CDS-5UTRENST00000529807ENST00000532552INTS4chr11

77649697

-ALG8chr11

77820627

-
5CDS-5UTRENST00000534064ENST00000532552INTS4chr11

77649697

-ALG8chr11

77817958

-
5CDS-5UTRENST00000534064ENST00000532552INTS4chr11

77649697

-ALG8chr11

77820627

-
5CDS-intronENST00000534064ENST00000532552INTS4chr11

77602364

-ALG8chr11

77817992

-
5CDS-intronENST00000535943ENST00000532552INTS4chr11

77602364

-ALG8chr11

77817992

-
5UTR-3CDSENST00000525931ENST00000299626INTS4chr11

77649697

-ALG8chr11

77817958

-
5UTR-3CDSENST00000525931ENST00000299626INTS4chr11

77649697

-ALG8chr11

77820627

-
5UTR-3CDSENST00000525931ENST00000376156INTS4chr11

77649697

-ALG8chr11

77817958

-
5UTR-3CDSENST00000525931ENST00000376156INTS4chr11

77649697

-ALG8chr11

77820627

-
5UTR-5UTRENST00000525931ENST00000532552INTS4chr11

77649697

-ALG8chr11

77817958

-
5UTR-5UTRENST00000525931ENST00000532552INTS4chr11

77649697

-ALG8chr11

77820627

-
Frame-shiftENST00000529807ENST00000299626INTS4chr11

77649697

-ALG8chr11

77817958

-
Frame-shiftENST00000529807ENST00000376156INTS4chr11

77649697

-ALG8chr11

77817958

-
Frame-shiftENST00000534064ENST00000299626INTS4chr11

77649697

-ALG8chr11

77817958

-
Frame-shiftENST00000534064ENST00000376156INTS4chr11

77649697

-ALG8chr11

77817958

-
In-frameENST00000529807ENST00000299626INTS4chr11

77649697

-ALG8chr11

77820627

-
In-frameENST00000529807ENST00000376156INTS4chr11

77649697

-ALG8chr11

77820627

-
In-frameENST00000534064ENST00000299626INTS4chr11

77602364

-ALG8chr11

77817992

-
In-frameENST00000534064ENST00000299626INTS4chr11

77649697

-ALG8chr11

77820627

-
In-frameENST00000534064ENST00000376156INTS4chr11

77602364

-ALG8chr11

77817992

-
In-frameENST00000534064ENST00000376156INTS4chr11

77649697

-ALG8chr11

77820627

-
In-frameENST00000535943ENST00000299626INTS4chr11

77602364

-ALG8chr11

77817992

-
In-frameENST00000535943ENST00000376156INTS4chr11

77602364

-ALG8chr11

77817992

-
intron-3CDSENST00000525931ENST00000299626INTS4chr11

77602364

-ALG8chr11

77817992

-
intron-3CDSENST00000525931ENST00000376156INTS4chr11

77602364

-ALG8chr11

77817992

-
intron-3CDSENST00000527522ENST00000299626INTS4chr11

77602364

-ALG8chr11

77817992

-
intron-3CDSENST00000527522ENST00000299626INTS4chr11

77649697

-ALG8chr11

77817958

-
intron-3CDSENST00000527522ENST00000299626INTS4chr11

77649697

-ALG8chr11

77820627

-
intron-3CDSENST00000527522ENST00000376156INTS4chr11

77602364

-ALG8chr11

77817992

-
intron-3CDSENST00000527522ENST00000376156INTS4chr11

77649697

-ALG8chr11

77817958

-
intron-3CDSENST00000527522ENST00000376156INTS4chr11

77649697

-ALG8chr11

77820627

-
intron-3CDSENST00000529807ENST00000299626INTS4chr11

77602364

-ALG8chr11

77817992

-
intron-3CDSENST00000529807ENST00000376156INTS4chr11

77602364

-ALG8chr11

77817992

-
intron-3CDSENST00000535943ENST00000299626INTS4chr11

77649697

-ALG8chr11

77817958

-
intron-3CDSENST00000535943ENST00000299626INTS4chr11

77649697

-ALG8chr11

77820627

-
intron-3CDSENST00000535943ENST00000376156INTS4chr11

77649697

-ALG8chr11

77817958

-
intron-3CDSENST00000535943ENST00000376156INTS4chr11

77649697

-ALG8chr11

77820627

-
intron-5UTRENST00000527522ENST00000532552INTS4chr11

77649697

-ALG8chr11

77817958

-
intron-5UTRENST00000527522ENST00000532552INTS4chr11

77649697

-ALG8chr11

77820627

-
intron-5UTRENST00000535943ENST00000532552INTS4chr11

77649697

-ALG8chr11

77817958

-
intron-5UTRENST00000535943ENST00000532552INTS4chr11

77649697

-ALG8chr11

77820627

-
intron-intronENST00000525931ENST00000532552INTS4chr11

77602364

-ALG8chr11

77817992

-
intron-intronENST00000527522ENST00000532552INTS4chr11

77602364

-ALG8chr11

77817992

-
intron-intronENST00000529807ENST00000532552INTS4chr11

77602364

-ALG8chr11

77817992

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000534064INTS4chr1177602364-ENST00000299626ALG8chr1177817992-319226273531691044
ENST00000534064INTS4chr1177602364-ENST00000376156ALG8chr1177817992-32622627352992985
ENST00000535943INTS4chr1177602364-ENST00000299626ALG8chr1177817992-14208551381397419
ENST00000535943INTS4chr1177602364-ENST00000376156ALG8chr1177817992-14908551381220360
ENST00000534064INTS4chr1177649697-ENST00000299626ALG8chr1177820627-19051200351882615
ENST00000534064INTS4chr1177649697-ENST00000376156ALG8chr1177820627-19751200351705556
ENST00000529807INTS4chr1177649697-ENST00000299626ALG8chr1177820627-18931188231870615
ENST00000529807INTS4chr1177649697-ENST00000376156ALG8chr1177820627-19631188231693556

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000534064ENST00000299626INTS4chr1177602364-ALG8chr1177817992-0.000488220.99951184
ENST00000534064ENST00000376156INTS4chr1177602364-ALG8chr1177817992-0.0016105780.9983895
ENST00000535943ENST00000299626INTS4chr1177602364-ALG8chr1177817992-0.0028716890.9971283
ENST00000535943ENST00000376156INTS4chr1177602364-ALG8chr1177817992-0.0034020510.99659795
ENST00000534064ENST00000299626INTS4chr1177649697-ALG8chr1177820627-0.0045079650.995492
ENST00000534064ENST00000376156INTS4chr1177649697-ALG8chr1177820627-0.0045990340.99540097
ENST00000529807ENST00000299626INTS4chr1177649697-ALG8chr1177820627-0.0045431670.9954568
ENST00000529807ENST00000376156INTS4chr1177649697-ALG8chr1177820627-0.0046013270.9953987

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Fusion Genomic Features for INTS4-ALG8


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for INTS4-ALG8


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:77649697/chr11:77820627)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
INTS4

Q96HW7

ALG8

Q9BVK2

FUNCTION: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). {ECO:0000269|PubMed:23904267, ECO:0000305|PubMed:16239144}.FUNCTION: Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol before it is transferred to the nascent peptide (By similarity). Required for PKD1/Polycystin-1 maturation and localization to the plasma membrane of the primary cilia (By similarity). {ECO:0000250|UniProtKB:P40351, ECO:0000250|UniProtKB:Q6P8H8}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneINTS4chr11:77602364chr11:77817992ENST00000534064-2123145_183864964.0RepeatNote=HEAT 2
HgeneINTS4chr11:77602364chr11:77817992ENST00000534064-2123190_228864964.0RepeatNote=HEAT 3
HgeneINTS4chr11:77602364chr11:77817992ENST00000534064-2123229_263864964.0RepeatNote=HEAT 4
HgeneINTS4chr11:77602364chr11:77817992ENST00000534064-2123277_313864964.0RepeatNote=HEAT 5
HgeneINTS4chr11:77602364chr11:77817992ENST00000534064-2123369_405864964.0RepeatNote=HEAT 6
HgeneINTS4chr11:77602364chr11:77817992ENST00000534064-2123406_444864964.0RepeatNote=HEAT 7
HgeneINTS4chr11:77602364chr11:77817992ENST00000534064-2123446_484864964.0RepeatNote=HEAT 8
HgeneINTS4chr11:77602364chr11:77817992ENST00000534064-212366_105864964.0RepeatNote=HEAT 1
HgeneINTS4chr11:77602364chr11:77817992ENST00000535943-79145_183239339.0RepeatNote=HEAT 2
HgeneINTS4chr11:77602364chr11:77817992ENST00000535943-79190_228239339.0RepeatNote=HEAT 3
HgeneINTS4chr11:77602364chr11:77817992ENST00000535943-7966_105239339.0RepeatNote=HEAT 1
HgeneINTS4chr11:77649697chr11:77820627ENST00000529807-1012145_183388506.0RepeatNote=HEAT 2
HgeneINTS4chr11:77649697chr11:77820627ENST00000529807-1012190_228388506.0RepeatNote=HEAT 3
HgeneINTS4chr11:77649697chr11:77820627ENST00000529807-1012229_263388506.0RepeatNote=HEAT 4
HgeneINTS4chr11:77649697chr11:77820627ENST00000529807-1012277_313388506.0RepeatNote=HEAT 5
HgeneINTS4chr11:77649697chr11:77820627ENST00000529807-101266_105388506.0RepeatNote=HEAT 1
HgeneINTS4chr11:77649697chr11:77820627ENST00000534064-1023145_183388964.0RepeatNote=HEAT 2
HgeneINTS4chr11:77649697chr11:77820627ENST00000534064-1023190_228388964.0RepeatNote=HEAT 3
HgeneINTS4chr11:77649697chr11:77820627ENST00000534064-1023229_263388964.0RepeatNote=HEAT 4
HgeneINTS4chr11:77649697chr11:77820627ENST00000534064-1023277_313388964.0RepeatNote=HEAT 5
HgeneINTS4chr11:77649697chr11:77820627ENST00000534064-102366_105388964.0RepeatNote=HEAT 1
TgeneALG8chr11:77602364chr11:77817992ENST00000299626813368_388346527.0TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000299626813389_409346527.0TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000299626813427_449346527.0TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000299626813461_481346527.0TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000299626813488_508346527.0TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000376156814368_388346516.6666666666666TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000376156814389_409346516.6666666666666TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000376156814427_449346516.6666666666666TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000376156814461_481346516.6666666666666TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000376156814488_508346516.6666666666666TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000299626713334_354299527.0TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000299626713368_388299527.0TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000299626713389_409299527.0TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000299626713427_449299527.0TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000299626713461_481299527.0TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000299626713488_508299527.0TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000376156714334_354299516.6666666666666TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000376156714368_388299516.6666666666666TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000376156714389_409299516.6666666666666TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000376156714427_449299516.6666666666666TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000376156714461_481299516.6666666666666TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000376156714488_508299516.6666666666666TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneINTS4chr11:77602364chr11:77817992ENST00000529807-112145_1830506.0RepeatNote=HEAT 2
HgeneINTS4chr11:77602364chr11:77817992ENST00000529807-112190_2280506.0RepeatNote=HEAT 3
HgeneINTS4chr11:77602364chr11:77817992ENST00000529807-112229_2630506.0RepeatNote=HEAT 4
HgeneINTS4chr11:77602364chr11:77817992ENST00000529807-112277_3130506.0RepeatNote=HEAT 5
HgeneINTS4chr11:77602364chr11:77817992ENST00000529807-112369_4050506.0RepeatNote=HEAT 6
HgeneINTS4chr11:77602364chr11:77817992ENST00000529807-112406_4440506.0RepeatNote=HEAT 7
HgeneINTS4chr11:77602364chr11:77817992ENST00000529807-112446_4840506.0RepeatNote=HEAT 8
HgeneINTS4chr11:77602364chr11:77817992ENST00000529807-11266_1050506.0RepeatNote=HEAT 1
HgeneINTS4chr11:77602364chr11:77817992ENST00000535943-79229_263239339.0RepeatNote=HEAT 4
HgeneINTS4chr11:77602364chr11:77817992ENST00000535943-79277_313239339.0RepeatNote=HEAT 5
HgeneINTS4chr11:77602364chr11:77817992ENST00000535943-79369_405239339.0RepeatNote=HEAT 6
HgeneINTS4chr11:77602364chr11:77817992ENST00000535943-79406_444239339.0RepeatNote=HEAT 7
HgeneINTS4chr11:77602364chr11:77817992ENST00000535943-79446_484239339.0RepeatNote=HEAT 8
HgeneINTS4chr11:77649697chr11:77820627ENST00000529807-1012369_405388506.0RepeatNote=HEAT 6
HgeneINTS4chr11:77649697chr11:77820627ENST00000529807-1012406_444388506.0RepeatNote=HEAT 7
HgeneINTS4chr11:77649697chr11:77820627ENST00000529807-1012446_484388506.0RepeatNote=HEAT 8
HgeneINTS4chr11:77649697chr11:77820627ENST00000534064-1023369_405388964.0RepeatNote=HEAT 6
HgeneINTS4chr11:77649697chr11:77820627ENST00000534064-1023406_444388964.0RepeatNote=HEAT 7
HgeneINTS4chr11:77649697chr11:77820627ENST00000534064-1023446_484388964.0RepeatNote=HEAT 8
HgeneINTS4chr11:77649697chr11:77820627ENST00000535943-19145_1830339.0RepeatNote=HEAT 2
HgeneINTS4chr11:77649697chr11:77820627ENST00000535943-19190_2280339.0RepeatNote=HEAT 3
HgeneINTS4chr11:77649697chr11:77820627ENST00000535943-19229_2630339.0RepeatNote=HEAT 4
HgeneINTS4chr11:77649697chr11:77820627ENST00000535943-19277_3130339.0RepeatNote=HEAT 5
HgeneINTS4chr11:77649697chr11:77820627ENST00000535943-19369_4050339.0RepeatNote=HEAT 6
HgeneINTS4chr11:77649697chr11:77820627ENST00000535943-19406_4440339.0RepeatNote=HEAT 7
HgeneINTS4chr11:77649697chr11:77820627ENST00000535943-19446_4840339.0RepeatNote=HEAT 8
HgeneINTS4chr11:77649697chr11:77820627ENST00000535943-1966_1050339.0RepeatNote=HEAT 1
TgeneALG8chr11:77602364chr11:77817992ENST00000299626813103_122346527.0TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000299626813143_163346527.0TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000299626813188_208346527.0TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000299626813238_258346527.0TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000299626813334_354346527.0TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST000002996268134_24346527.0TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000376156814103_122346516.6666666666666TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000376156814143_163346516.6666666666666TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000376156814188_208346516.6666666666666TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000376156814238_258346516.6666666666666TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST00000376156814334_354346516.6666666666666TransmembraneHelical
TgeneALG8chr11:77602364chr11:77817992ENST000003761568144_24346516.6666666666666TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000299626713103_122299527.0TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000299626713143_163299527.0TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000299626713188_208299527.0TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000299626713238_258299527.0TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST000002996267134_24299527.0TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000376156714103_122299516.6666666666666TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000376156714143_163299516.6666666666666TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000376156714188_208299516.6666666666666TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST00000376156714238_258299516.6666666666666TransmembraneHelical
TgeneALG8chr11:77649697chr11:77820627ENST000003761567144_24299516.6666666666666TransmembraneHelical


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Fusion Gene Sequence for INTS4-ALG8


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>39941_39941_1_INTS4-ALG8_INTS4_chr11_77602364_ENST00000534064_ALG8_chr11_77817992_ENST00000299626_length(transcript)=3192nt_BP=2627nt
TAGTGTACGGAAGCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGC
CACAGGAGGAAATTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCC
CAGCAGATGCTTTGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAAC
ATTATTACAAGGAGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACT
GCATTATGGATGATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCA
CTAAGCTACCAGAGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGCATCTGACAGATACGTCTCATGGTGTAAGAAATA
AGTGCCTGCAGTTACTTGGCAATCTTGGCTCTTTGGAGAAAAGTGTCACAAAAGATGCAGAAGGCCTAGCTGCCAGAGATGTCCAGAAGA
TTATAGGGGATTACTTCAGTGACCAAGACCCACGTGTCAGAACAGCAGCTATAAAAGCCATGTTGCAGCTCCATGAAAGAGGACTGAAAT
TACACCAAACAATTTATAATCAGGCCTGTAAATTACTCTCTGATGACTATGAACAAGTGCGCAGTGCTGCAGTCCAGCTTATCTGGGTCG
TCAGTCAGCTCTATCCTGAAAGCATTGTCCCAATTCCTTCTTCTAATGAAGAAATACGCTTAGTTGATGATGCGTTTGGCAAAATTTGTC
ACATGGTCAGTGATGGCTCTTGGGTGGTTCGTGTTCAGGCAGCAAAACTGTTGGGCTCTATGGAGCAAGTCAGTTCTCATTTCTTGGAGC
AGACCCTTGACAAGAAGCTGATGTCAGATCTGAGGAGGAAACGTACTGCACATGAGCGTGCCAAGGAACTTTACAGTTCGGGGGAGTTTT
CCAGTGGCAGAAAGTGGGGAGATGATGCTCCCAAGGAAGAAGTAGATACCGGGGCTGTGAACTTGATTGAGTCAGGAGCTTGTGGAGCTT
TTGTTCATGGGTTGGAAGATGAGATGTATGAGGTTCGTATTGCTGCTGTGGAGGCCCTCTGCATGTTGGCCCAGTCTTCACCCTCTTTTG
CTGAGAAGTGCCTTGATTTCCTAGTTGACATGTTCAACGATGAAATTGAGGAAGTACGTCTGCAGTCTATACATACCATGAGAAAAATCT
CTAACAACATCACCCTCCGAGAAGATCAGCTTGACACTGTCCTGGCTGTGCTAGAGGATTCATCCAGAGATATTCGAGAGGCTCTTCATG
AACTCTTATGCTGTACTAATGTTTCAACCAAAGAAGGGATTCATCTTGCATTGGTGGAGCTGCTGAAAAATTTAACCAAGTACCCTACTG
ATAGGGACTCCATATGGAAGTGCTTGAAGTTTCTGGGAAGTCGGCATCCAACCCTGGTGCTTCCCTTGGTGCCAGAGCTTCTGAGCACCC
ACCCATTTTTTGACACAGCTGAACCAGACATGGATGATCCAGCTTATATTGCAGTTTTGGTACTTATTTTCAATGCTGCTAAAACCTGTC
CAACAATGCCAGCATTGTTCTCAGATCACACCTTCAGGCACTATGCCTACCTCCGAGACAGTCTTTCTCATCTTGTTCCTGCCTTGAGGT
TACCAGGTAGAAAACTGGTGTCATCAGCTGTTTCTCCCAGCATCATACCTCAAGAGGATCCTTCCCAGCAGTTCCTGCAGCAGAGCCTTG
AAAGAGTGTATAGTCTTCAGCACTTGGACCCTCAGGGAGCCCAGGAGCTGCTGGAATTCACCATCAGGGATCTGCAAAGACTTGGAGAAC
TTCAATCTGAATTGGCAGGAGTAGCTGATTTCTCTGCCACCTATCTTCGCTGTCAACTACTTCTCATCAAGGCCTTGCAGGAAAAGTTGT
GGAATGTAGCTGCCCCTTTGTATTTGAAGCAGAGTGATTTGGCCTCAGCAGCAGCGAAACAGATTATGGAAGAGACCTACAAAATGGAAT
TCATGTACAGTGGTGTGGAGAATAAGCAGGTGGTGATTATACATCACATGAGGCTGCAGGCCAAAGCTTTGCAACTTATAGTAACAGCAC
GAACTACACGAGGACTTGACCCCTTATTTGGGATGTGTGAAAAATTTTTACAGGAAGTAGACTTTTTTCAGAGGTATTTCATCGCTGATT
TGCCCCACTTGCAGGACAGCTTTGTGGACAAACTCCTTGACCTTATGCCCCGACTCATGACATCCAAACCTGCAGAAGTGGTCAAAATTC
TACAGACCATGCTGCGACAGAGTGCCTTTCTGCATCTCCCGCTTCCAGAGCAGATCCACAAAGCCTCAGCCACCATCATCGAGCCAGCGG
GCGAGTCAGACAACCCTTTGCGGTTTACCTCTGGGTTGGTGGTTGCCCTGGATGTTGATGCAACCCTGGAGCATGTGCAGGATCCTCAGA
ACACTGTTAAGGTCCAGCCCTCTATTTTCTGTCTTTGGTTTAAACCCCAAGGGCCCAGAGGCTTTCTCCGATGTCTAACTCTTTGTGCCT
TGAGCTCCTTTATGTTTGGGTGGCATGTTCATGAAAAAGCCATACTTCTAGCAATTCTCCCAATGAGCCTTTTGTCTGTGGGAAAAGCAG
GAGACGCTTCGATTTTTCTGATTCTGACCACAACAGGACATTATTCCCTCTTTCCTCTGCTCTTCACTGCACCAGAACTTCCCATTAAAA
TCTTACTCATGTTACTATTCACCATATATAGTATTTCGTCACTGAAGACTTTATTCAGAAAAGAAAAACCTCTTTTTAATTGGATGGAAA
CTTTCTACCTGCTTGGCCTGGGGCCTCTGGAAGTCTGCTGTGAATTTGTATTCCCTTTCACCTCCTGGAAGGTGAAGTACCCCTTCATCC
CTTTGTTACTAACCTCAGTGTATTGTGCAGTAGGCATCACATATGCTTGGTTCAAACTGTATGTTTCAGTATTGATTGACTCTGCTATTG

>39941_39941_1_INTS4-ALG8_INTS4_chr11_77602364_ENST00000534064_ALG8_chr11_77817992_ENST00000299626_length(amino acids)=1044AA_BP=864
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSL
EKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPI
PSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPK
EEVDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQLD
TVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMD
DPAYIAVLVLIFNAAKTCPTMPALFSDHTFRHYAYLRDSLSHLVPALRLPGRKLVSSAVSPSIIPQEDPSQQFLQQSLERVYSLQHLDPQ
GAQELLEFTIRDLQRLGELQSELAGVADFSATYLRCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVV
IIHHMRLQAKALQLIVTARTTRGLDPLFGMCEKFLQEVDFFQRYFIADLPHLQDSFVDKLLDLMPRLMTSKPAEVVKILQTMLRQSAFLH
LPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHE
KAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEV

--------------------------------------------------------------
>39941_39941_2_INTS4-ALG8_INTS4_chr11_77602364_ENST00000534064_ALG8_chr11_77817992_ENST00000376156_length(transcript)=3262nt_BP=2627nt
TAGTGTACGGAAGCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGC
CACAGGAGGAAATTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCC
CAGCAGATGCTTTGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAAC
ATTATTACAAGGAGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACT
GCATTATGGATGATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCA
CTAAGCTACCAGAGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGCATCTGACAGATACGTCTCATGGTGTAAGAAATA
AGTGCCTGCAGTTACTTGGCAATCTTGGCTCTTTGGAGAAAAGTGTCACAAAAGATGCAGAAGGCCTAGCTGCCAGAGATGTCCAGAAGA
TTATAGGGGATTACTTCAGTGACCAAGACCCACGTGTCAGAACAGCAGCTATAAAAGCCATGTTGCAGCTCCATGAAAGAGGACTGAAAT
TACACCAAACAATTTATAATCAGGCCTGTAAATTACTCTCTGATGACTATGAACAAGTGCGCAGTGCTGCAGTCCAGCTTATCTGGGTCG
TCAGTCAGCTCTATCCTGAAAGCATTGTCCCAATTCCTTCTTCTAATGAAGAAATACGCTTAGTTGATGATGCGTTTGGCAAAATTTGTC
ACATGGTCAGTGATGGCTCTTGGGTGGTTCGTGTTCAGGCAGCAAAACTGTTGGGCTCTATGGAGCAAGTCAGTTCTCATTTCTTGGAGC
AGACCCTTGACAAGAAGCTGATGTCAGATCTGAGGAGGAAACGTACTGCACATGAGCGTGCCAAGGAACTTTACAGTTCGGGGGAGTTTT
CCAGTGGCAGAAAGTGGGGAGATGATGCTCCCAAGGAAGAAGTAGATACCGGGGCTGTGAACTTGATTGAGTCAGGAGCTTGTGGAGCTT
TTGTTCATGGGTTGGAAGATGAGATGTATGAGGTTCGTATTGCTGCTGTGGAGGCCCTCTGCATGTTGGCCCAGTCTTCACCCTCTTTTG
CTGAGAAGTGCCTTGATTTCCTAGTTGACATGTTCAACGATGAAATTGAGGAAGTACGTCTGCAGTCTATACATACCATGAGAAAAATCT
CTAACAACATCACCCTCCGAGAAGATCAGCTTGACACTGTCCTGGCTGTGCTAGAGGATTCATCCAGAGATATTCGAGAGGCTCTTCATG
AACTCTTATGCTGTACTAATGTTTCAACCAAAGAAGGGATTCATCTTGCATTGGTGGAGCTGCTGAAAAATTTAACCAAGTACCCTACTG
ATAGGGACTCCATATGGAAGTGCTTGAAGTTTCTGGGAAGTCGGCATCCAACCCTGGTGCTTCCCTTGGTGCCAGAGCTTCTGAGCACCC
ACCCATTTTTTGACACAGCTGAACCAGACATGGATGATCCAGCTTATATTGCAGTTTTGGTACTTATTTTCAATGCTGCTAAAACCTGTC
CAACAATGCCAGCATTGTTCTCAGATCACACCTTCAGGCACTATGCCTACCTCCGAGACAGTCTTTCTCATCTTGTTCCTGCCTTGAGGT
TACCAGGTAGAAAACTGGTGTCATCAGCTGTTTCTCCCAGCATCATACCTCAAGAGGATCCTTCCCAGCAGTTCCTGCAGCAGAGCCTTG
AAAGAGTGTATAGTCTTCAGCACTTGGACCCTCAGGGAGCCCAGGAGCTGCTGGAATTCACCATCAGGGATCTGCAAAGACTTGGAGAAC
TTCAATCTGAATTGGCAGGAGTAGCTGATTTCTCTGCCACCTATCTTCGCTGTCAACTACTTCTCATCAAGGCCTTGCAGGAAAAGTTGT
GGAATGTAGCTGCCCCTTTGTATTTGAAGCAGAGTGATTTGGCCTCAGCAGCAGCGAAACAGATTATGGAAGAGACCTACAAAATGGAAT
TCATGTACAGTGGTGTGGAGAATAAGCAGGTGGTGATTATACATCACATGAGGCTGCAGGCCAAAGCTTTGCAACTTATAGTAACAGCAC
GAACTACACGAGGACTTGACCCCTTATTTGGGATGTGTGAAAAATTTTTACAGGAAGTAGACTTTTTTCAGAGGTATTTCATCGCTGATT
TGCCCCACTTGCAGGACAGCTTTGTGGACAAACTCCTTGACCTTATGCCCCGACTCATGACATCCAAACCTGCAGAAGTGGTCAAAATTC
TACAGACCATGCTGCGACAGAGTGCCTTTCTGCATCTCCCGCTTCCAGAGCAGATCCACAAAGCCTCAGCCACCATCATCGAGCCAGCGG
GCGAGTCAGACAACCCTTTGCGGTTTACCTCTGGGTTGGTGGTTGCCCTGGATGTTGATGCAACCCTGGAGCATGTGCAGGATCCTCAGA
ACACTGTTAAGGTCCAGCCCTCTATTTTCTGTCTTTGGTTTAAACCCCAAGGGCCCAGAGGCTTTCTCCGATGTCTAACTCTTTGTGCCT
TGAGCTCCTTTATGTTTGGGTGGCATGTTCATGAAAAAGCCATACTTCTAGCAATTCTCCCAATGAGCCTTTTGTCTGTGGGAAAAGCAG
GAGACGCTTCGATTTTTCTGATTCTGACCACAACAGGACATTATTCCCTCTTTCCTCTGCTCTTCACTGCACCAGAACTTCCCATTAAAA
TCTTACTCATGTTACTATTCACCATATATAGTATTTCGTCACTGAAGACTTTATTCAGACGGAGTTTCACCCTTGTTGCCCAGGCTGGAG
TGCAATGGCACGATCTCAGCTAACTGAAACCTCCGCCTCCCAGAAAAGAAAAACCTCTTTTTAATTGGATGGAAACTTTCTACCTGCTTG
GCCTGGGGCCTCTGGAAGTCTGCTGTGAATTTGTATTCCCTTTCACCTCCTGGAAGGTGAAGTACCCCTTCATCCCTTTGTTACTAACCT
CAGTGTATTGTGCAGTAGGCATCACATATGCTTGGTTCAAACTGTATGTTTCAGTATTGATTGACTCTGCTATTGGCAAGACAAAGAAAC

>39941_39941_2_INTS4-ALG8_INTS4_chr11_77602364_ENST00000534064_ALG8_chr11_77817992_ENST00000376156_length(amino acids)=985AA_BP=864
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSL
EKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPI
PSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPK
EEVDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQLD
TVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMD
DPAYIAVLVLIFNAAKTCPTMPALFSDHTFRHYAYLRDSLSHLVPALRLPGRKLVSSAVSPSIIPQEDPSQQFLQQSLERVYSLQHLDPQ
GAQELLEFTIRDLQRLGELQSELAGVADFSATYLRCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVV
IIHHMRLQAKALQLIVTARTTRGLDPLFGMCEKFLQEVDFFQRYFIADLPHLQDSFVDKLLDLMPRLMTSKPAEVVKILQTMLRQSAFLH
LPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHE

--------------------------------------------------------------
>39941_39941_3_INTS4-ALG8_INTS4_chr11_77602364_ENST00000535943_ALG8_chr11_77817992_ENST00000299626_length(transcript)=1420nt_BP=855nt
AGGCATCTCCTTCTTGATGTCAAAGTCCCCAGGAGGCATCGTTAACTATCGTAACGTTACCTGCCGAGCATGAGATGGGAGGAAGTGTCA
TAGTCCAGTGGACGGTTTTTTCCAGGCTACTGTGAAACCTGATGTGTTATGCCGGCCCTGAAACAGACAGCTTCCCAAGTGACTCAGACC
TTAAGGGATCTGCAAAGACTTGGAGAACTTCAATCTGAATTGGCAGGAGTAGCTGATTTCTCTGCCACCTATCTTCGCTGTCAACTACTT
CTCATCAAGGCCTTGCAGGAAAAGTTGTGGAATGTAGCTGCCCCTTTGTATTTGAAGCAGAGTGATTTGGCCTCAGCAGCAGCGAAACAG
ATTATGGAAGAGACCTACAAAATGGAATTCATGTACAGTGGTGTGGAGAATAAGCAGGTGGTGATTATACATCACATGAGGCTGCAGGCC
AAAGCTTTGCAACTTATAGTAACAGCACGAACTACACGAGGACTTGACCCCTTATTTGGGATGTGTGAAAAATTTTTACAGGAAGTAGAC
TTTTTTCAGAGGTATTTCATCGCTGATTTGCCCCACTTGCAGGACAGCTTTGTGGACAAACTCCTTGACCTTATGCCCCGACTCATGACA
TCCAAACCTGCAGAAGTGGTCAAAATTCTACAGACCATGCTGCGACAGAGTGCCTTTCTGCATCTCCCGCTTCCAGAGCAGATCCACAAA
GCCTCAGCCACCATCATCGAGCCAGCGGGCGAGTCAGACAACCCTTTGCGGTTTACCTCTGGGTTGGTGGTTGCCCTGGATGTTGATGCA
ACCCTGGAGCATGTGCAGGATCCTCAGAACACTGTTAAGGTCCAGCCCTCTATTTTCTGTCTTTGGTTTAAACCCCAAGGGCCCAGAGGC
TTTCTCCGATGTCTAACTCTTTGTGCCTTGAGCTCCTTTATGTTTGGGTGGCATGTTCATGAAAAAGCCATACTTCTAGCAATTCTCCCA
ATGAGCCTTTTGTCTGTGGGAAAAGCAGGAGACGCTTCGATTTTTCTGATTCTGACCACAACAGGACATTATTCCCTCTTTCCTCTGCTC
TTCACTGCACCAGAACTTCCCATTAAAATCTTACTCATGTTACTATTCACCATATATAGTATTTCGTCACTGAAGACTTTATTCAGAAAA
GAAAAACCTCTTTTTAATTGGATGGAAACTTTCTACCTGCTTGGCCTGGGGCCTCTGGAAGTCTGCTGTGAATTTGTATTCCCTTTCACC
TCCTGGAAGGTGAAGTACCCCTTCATCCCTTTGTTACTAACCTCAGTGTATTGTGCAGTAGGCATCACATATGCTTGGTTCAAACTGTAT

>39941_39941_3_INTS4-ALG8_INTS4_chr11_77602364_ENST00000535943_ALG8_chr11_77817992_ENST00000299626_length(amino acids)=419AA_BP=239
MPALKQTASQVTQTLRDLQRLGELQSELAGVADFSATYLRCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVE
NKQVVIIHHMRLQAKALQLIVTARTTRGLDPLFGMCEKFLQEVDFFQRYFIADLPHLQDSFVDKLLDLMPRLMTSKPAEVVKILQTMLRQ
SAFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQPSIFCLWFKPQGPRGFLRCLTLCALSSFMFG
WHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGL

--------------------------------------------------------------
>39941_39941_4_INTS4-ALG8_INTS4_chr11_77602364_ENST00000535943_ALG8_chr11_77817992_ENST00000376156_length(transcript)=1490nt_BP=855nt
AGGCATCTCCTTCTTGATGTCAAAGTCCCCAGGAGGCATCGTTAACTATCGTAACGTTACCTGCCGAGCATGAGATGGGAGGAAGTGTCA
TAGTCCAGTGGACGGTTTTTTCCAGGCTACTGTGAAACCTGATGTGTTATGCCGGCCCTGAAACAGACAGCTTCCCAAGTGACTCAGACC
TTAAGGGATCTGCAAAGACTTGGAGAACTTCAATCTGAATTGGCAGGAGTAGCTGATTTCTCTGCCACCTATCTTCGCTGTCAACTACTT
CTCATCAAGGCCTTGCAGGAAAAGTTGTGGAATGTAGCTGCCCCTTTGTATTTGAAGCAGAGTGATTTGGCCTCAGCAGCAGCGAAACAG
ATTATGGAAGAGACCTACAAAATGGAATTCATGTACAGTGGTGTGGAGAATAAGCAGGTGGTGATTATACATCACATGAGGCTGCAGGCC
AAAGCTTTGCAACTTATAGTAACAGCACGAACTACACGAGGACTTGACCCCTTATTTGGGATGTGTGAAAAATTTTTACAGGAAGTAGAC
TTTTTTCAGAGGTATTTCATCGCTGATTTGCCCCACTTGCAGGACAGCTTTGTGGACAAACTCCTTGACCTTATGCCCCGACTCATGACA
TCCAAACCTGCAGAAGTGGTCAAAATTCTACAGACCATGCTGCGACAGAGTGCCTTTCTGCATCTCCCGCTTCCAGAGCAGATCCACAAA
GCCTCAGCCACCATCATCGAGCCAGCGGGCGAGTCAGACAACCCTTTGCGGTTTACCTCTGGGTTGGTGGTTGCCCTGGATGTTGATGCA
ACCCTGGAGCATGTGCAGGATCCTCAGAACACTGTTAAGGTCCAGCCCTCTATTTTCTGTCTTTGGTTTAAACCCCAAGGGCCCAGAGGC
TTTCTCCGATGTCTAACTCTTTGTGCCTTGAGCTCCTTTATGTTTGGGTGGCATGTTCATGAAAAAGCCATACTTCTAGCAATTCTCCCA
ATGAGCCTTTTGTCTGTGGGAAAAGCAGGAGACGCTTCGATTTTTCTGATTCTGACCACAACAGGACATTATTCCCTCTTTCCTCTGCTC
TTCACTGCACCAGAACTTCCCATTAAAATCTTACTCATGTTACTATTCACCATATATAGTATTTCGTCACTGAAGACTTTATTCAGACGG
AGTTTCACCCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCTCAGCTAACTGAAACCTCCGCCTCCCAGAAAAGAAAAACCTCTTTTT
AATTGGATGGAAACTTTCTACCTGCTTGGCCTGGGGCCTCTGGAAGTCTGCTGTGAATTTGTATTCCCTTTCACCTCCTGGAAGGTGAAG
TACCCCTTCATCCCTTTGTTACTAACCTCAGTGTATTGTGCAGTAGGCATCACATATGCTTGGTTCAAACTGTATGTTTCAGTATTGATT

>39941_39941_4_INTS4-ALG8_INTS4_chr11_77602364_ENST00000535943_ALG8_chr11_77817992_ENST00000376156_length(amino acids)=360AA_BP=239
MPALKQTASQVTQTLRDLQRLGELQSELAGVADFSATYLRCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVE
NKQVVIIHHMRLQAKALQLIVTARTTRGLDPLFGMCEKFLQEVDFFQRYFIADLPHLQDSFVDKLLDLMPRLMTSKPAEVVKILQTMLRQ
SAFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQPSIFCLWFKPQGPRGFLRCLTLCALSSFMFG
WHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRRSFTLVAQAGVQWHDLS

--------------------------------------------------------------
>39941_39941_5_INTS4-ALG8_INTS4_chr11_77649697_ENST00000529807_ALG8_chr11_77820627_ENST00000299626_length(transcript)=1893nt_BP=1188nt
GCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGCCACAGGAGGAAA
TTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCCCAGCAGATGCTT
TGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAACATTATTACAAGG
AGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACTGCATTATGGATG
ATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCACTAAGCTACCAG
AGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGCATCTGACAGATACGTCTCATGGTGTAAGAAATAAGTGCCTGCAGT
TACTTGGCAATCTTGGCTCTTTGGAGAAAAGTGTCACAAAAGATGCAGAAGGCCTAGCTGCCAGAGATGTCCAGAAGATTATAGGGGATT
ACTTCAGTGACCAAGACCCACGTGTCAGAACAGCAGCTATAAAAGCCATGTTGCAGCTCCATGAAAGAGGACTGAAATTACACCAAACAA
TTTATAATCAGGCCTGTAAATTACTCTCTGATGACTATGAACAAGTGCGCAGTGCTGCAGTCCAGCTTATCTGGGTCGTCAGTCAGCTCT
ATCCTGAAAGCATTGTCCCAATTCCTTCTTCTAATGAAGAAATACGCTTAGTTGATGATGCGTTTGGCAAAATTTGTCACATGGTCAGTG
ATGGCTCTTGGGTGGTTCGTGTTCAGGCAGCAAAACTGTTGGGCTCTATGGAGCAAGTCAGTTCTCATTTCTTGGAGCAGACCCTTGACA
AGAAGCTGATGTCAGATCTGAGGAGGAAACGTACTGCACATGAGCGTGCCAAGGAACTTTACAGTTCGGGGGAGTTTTCCAGTGGCAGAA
AGTGGGGAGATGATGCTCCCAAGGAAGAAGTAGATACCGGGGCTGTGAACTTGATTGAGTCAGGAGCTTGTGGAGCTTTTGTTCATGGGT
TGGAAGATGAGATGTATGGTTTGAAATTGAAATTTCTTGATCCCAACAATATTCCCAAGGCCTCAATGACAAGTGGTTTGGTTCAGCAGT
TCCAACACACAGTCCTTCCCTCAGTGACTCCCTTGGCAACCCTCATCTGCACACTGATTGCCATATTGCCCTCTATTTTCTGTCTTTGGT
TTAAACCCCAAGGGCCCAGAGGCTTTCTCCGATGTCTAACTCTTTGTGCCTTGAGCTCCTTTATGTTTGGGTGGCATGTTCATGAAAAAG
CCATACTTCTAGCAATTCTCCCAATGAGCCTTTTGTCTGTGGGAAAAGCAGGAGACGCTTCGATTTTTCTGATTCTGACCACAACAGGAC
ATTATTCCCTCTTTCCTCTGCTCTTCACTGCACCAGAACTTCCCATTAAAATCTTACTCATGTTACTATTCACCATATATAGTATTTCGT
CACTGAAGACTTTATTCAGAAAAGAAAAACCTCTTTTTAATTGGATGGAAACTTTCTACCTGCTTGGCCTGGGGCCTCTGGAAGTCTGCT
GTGAATTTGTATTCCCTTTCACCTCCTGGAAGGTGAAGTACCCCTTCATCCCTTTGTTACTAACCTCAGTGTATTGTGCAGTAGGCATCA
CATATGCTTGGTTCAAACTGTATGTTTCAGTATTGATTGACTCTGCTATTGGCAAGACAAAGAAACAATGAATAAAGGAACTGCTTAGAT

>39941_39941_5_INTS4-ALG8_INTS4_chr11_77649697_ENST00000529807_ALG8_chr11_77820627_ENST00000299626_length(amino acids)=615AA_BP=388
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSL
EKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPI
PSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPK
EEVDTGAVNLIESGACGAFVHGLEDEMYGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRG
FLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRK

--------------------------------------------------------------
>39941_39941_6_INTS4-ALG8_INTS4_chr11_77649697_ENST00000529807_ALG8_chr11_77820627_ENST00000376156_length(transcript)=1963nt_BP=1188nt
GCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGCCACAGGAGGAAA
TTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCCCAGCAGATGCTT
TGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAACATTATTACAAGG
AGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACTGCATTATGGATG
ATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCACTAAGCTACCAG
AGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGCATCTGACAGATACGTCTCATGGTGTAAGAAATAAGTGCCTGCAGT
TACTTGGCAATCTTGGCTCTTTGGAGAAAAGTGTCACAAAAGATGCAGAAGGCCTAGCTGCCAGAGATGTCCAGAAGATTATAGGGGATT
ACTTCAGTGACCAAGACCCACGTGTCAGAACAGCAGCTATAAAAGCCATGTTGCAGCTCCATGAAAGAGGACTGAAATTACACCAAACAA
TTTATAATCAGGCCTGTAAATTACTCTCTGATGACTATGAACAAGTGCGCAGTGCTGCAGTCCAGCTTATCTGGGTCGTCAGTCAGCTCT
ATCCTGAAAGCATTGTCCCAATTCCTTCTTCTAATGAAGAAATACGCTTAGTTGATGATGCGTTTGGCAAAATTTGTCACATGGTCAGTG
ATGGCTCTTGGGTGGTTCGTGTTCAGGCAGCAAAACTGTTGGGCTCTATGGAGCAAGTCAGTTCTCATTTCTTGGAGCAGACCCTTGACA
AGAAGCTGATGTCAGATCTGAGGAGGAAACGTACTGCACATGAGCGTGCCAAGGAACTTTACAGTTCGGGGGAGTTTTCCAGTGGCAGAA
AGTGGGGAGATGATGCTCCCAAGGAAGAAGTAGATACCGGGGCTGTGAACTTGATTGAGTCAGGAGCTTGTGGAGCTTTTGTTCATGGGT
TGGAAGATGAGATGTATGGTTTGAAATTGAAATTTCTTGATCCCAACAATATTCCCAAGGCCTCAATGACAAGTGGTTTGGTTCAGCAGT
TCCAACACACAGTCCTTCCCTCAGTGACTCCCTTGGCAACCCTCATCTGCACACTGATTGCCATATTGCCCTCTATTTTCTGTCTTTGGT
TTAAACCCCAAGGGCCCAGAGGCTTTCTCCGATGTCTAACTCTTTGTGCCTTGAGCTCCTTTATGTTTGGGTGGCATGTTCATGAAAAAG
CCATACTTCTAGCAATTCTCCCAATGAGCCTTTTGTCTGTGGGAAAAGCAGGAGACGCTTCGATTTTTCTGATTCTGACCACAACAGGAC
ATTATTCCCTCTTTCCTCTGCTCTTCACTGCACCAGAACTTCCCATTAAAATCTTACTCATGTTACTATTCACCATATATAGTATTTCGT
CACTGAAGACTTTATTCAGACGGAGTTTCACCCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCTCAGCTAACTGAAACCTCCGCCTC
CCAGAAAAGAAAAACCTCTTTTTAATTGGATGGAAACTTTCTACCTGCTTGGCCTGGGGCCTCTGGAAGTCTGCTGTGAATTTGTATTCC
CTTTCACCTCCTGGAAGGTGAAGTACCCCTTCATCCCTTTGTTACTAACCTCAGTGTATTGTGCAGTAGGCATCACATATGCTTGGTTCA

>39941_39941_6_INTS4-ALG8_INTS4_chr11_77649697_ENST00000529807_ALG8_chr11_77820627_ENST00000376156_length(amino acids)=556AA_BP=388
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSL
EKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPI
PSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPK
EEVDTGAVNLIESGACGAFVHGLEDEMYGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRG
FLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRR

--------------------------------------------------------------
>39941_39941_7_INTS4-ALG8_INTS4_chr11_77649697_ENST00000534064_ALG8_chr11_77820627_ENST00000299626_length(transcript)=1905nt_BP=1200nt
TAGTGTACGGAAGCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGC
CACAGGAGGAAATTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCC
CAGCAGATGCTTTGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAAC
ATTATTACAAGGAGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACT
GCATTATGGATGATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCA
CTAAGCTACCAGAGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGCATCTGACAGATACGTCTCATGGTGTAAGAAATA
AGTGCCTGCAGTTACTTGGCAATCTTGGCTCTTTGGAGAAAAGTGTCACAAAAGATGCAGAAGGCCTAGCTGCCAGAGATGTCCAGAAGA
TTATAGGGGATTACTTCAGTGACCAAGACCCACGTGTCAGAACAGCAGCTATAAAAGCCATGTTGCAGCTCCATGAAAGAGGACTGAAAT
TACACCAAACAATTTATAATCAGGCCTGTAAATTACTCTCTGATGACTATGAACAAGTGCGCAGTGCTGCAGTCCAGCTTATCTGGGTCG
TCAGTCAGCTCTATCCTGAAAGCATTGTCCCAATTCCTTCTTCTAATGAAGAAATACGCTTAGTTGATGATGCGTTTGGCAAAATTTGTC
ACATGGTCAGTGATGGCTCTTGGGTGGTTCGTGTTCAGGCAGCAAAACTGTTGGGCTCTATGGAGCAAGTCAGTTCTCATTTCTTGGAGC
AGACCCTTGACAAGAAGCTGATGTCAGATCTGAGGAGGAAACGTACTGCACATGAGCGTGCCAAGGAACTTTACAGTTCGGGGGAGTTTT
CCAGTGGCAGAAAGTGGGGAGATGATGCTCCCAAGGAAGAAGTAGATACCGGGGCTGTGAACTTGATTGAGTCAGGAGCTTGTGGAGCTT
TTGTTCATGGGTTGGAAGATGAGATGTATGGTTTGAAATTGAAATTTCTTGATCCCAACAATATTCCCAAGGCCTCAATGACAAGTGGTT
TGGTTCAGCAGTTCCAACACACAGTCCTTCCCTCAGTGACTCCCTTGGCAACCCTCATCTGCACACTGATTGCCATATTGCCCTCTATTT
TCTGTCTTTGGTTTAAACCCCAAGGGCCCAGAGGCTTTCTCCGATGTCTAACTCTTTGTGCCTTGAGCTCCTTTATGTTTGGGTGGCATG
TTCATGAAAAAGCCATACTTCTAGCAATTCTCCCAATGAGCCTTTTGTCTGTGGGAAAAGCAGGAGACGCTTCGATTTTTCTGATTCTGA
CCACAACAGGACATTATTCCCTCTTTCCTCTGCTCTTCACTGCACCAGAACTTCCCATTAAAATCTTACTCATGTTACTATTCACCATAT
ATAGTATTTCGTCACTGAAGACTTTATTCAGAAAAGAAAAACCTCTTTTTAATTGGATGGAAACTTTCTACCTGCTTGGCCTGGGGCCTC
TGGAAGTCTGCTGTGAATTTGTATTCCCTTTCACCTCCTGGAAGGTGAAGTACCCCTTCATCCCTTTGTTACTAACCTCAGTGTATTGTG
CAGTAGGCATCACATATGCTTGGTTCAAACTGTATGTTTCAGTATTGATTGACTCTGCTATTGGCAAGACAAAGAAACAATGAATAAAGG

>39941_39941_7_INTS4-ALG8_INTS4_chr11_77649697_ENST00000534064_ALG8_chr11_77820627_ENST00000299626_length(amino acids)=615AA_BP=388
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSL
EKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPI
PSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPK
EEVDTGAVNLIESGACGAFVHGLEDEMYGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRG
FLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRK

--------------------------------------------------------------
>39941_39941_8_INTS4-ALG8_INTS4_chr11_77649697_ENST00000534064_ALG8_chr11_77820627_ENST00000376156_length(transcript)=1975nt_BP=1200nt
TAGTGTACGGAAGCTGAGAGGGCCCGCGGGTAGGCATGGCGGCGCACCTTAAGAAGCGGGTTTATGAGGAATTCACGAAAGTGGTTCAGC
CACAGGAGGAAATTGCTACTAAGAAACTCCGACTAACAAAACCAAGTAAATCTGCAGCACTCCACATAGATCTGTGTAAAGCTACCTCCC
CAGCAGATGCTTTGCAATACTTGCTCCAGTTTGCCAGGAAGCCTGTCGAGGCGGAAAGCGTAGAGGGAGTAGTCAGGATTCTCTTGGAAC
ATTATTACAAGGAGAATGATCCATCTGTGAGACTGAAAATTGCATCATTGTTGGGTTTATTATCAAAGACAGCAGGATTTTCACCAGACT
GCATTATGGATGATGCCATCAACATCCTGCAGAATGAAAAGTCTCATCAAGTCCTAGCTCAACTGCTGGATACTTTGCTTGCAATTGGCA
CTAAGCTACCAGAGAATCAAGCTATCCAAATGCGATTAGTTGATGTGGCCTGCAAGCATCTGACAGATACGTCTCATGGTGTAAGAAATA
AGTGCCTGCAGTTACTTGGCAATCTTGGCTCTTTGGAGAAAAGTGTCACAAAAGATGCAGAAGGCCTAGCTGCCAGAGATGTCCAGAAGA
TTATAGGGGATTACTTCAGTGACCAAGACCCACGTGTCAGAACAGCAGCTATAAAAGCCATGTTGCAGCTCCATGAAAGAGGACTGAAAT
TACACCAAACAATTTATAATCAGGCCTGTAAATTACTCTCTGATGACTATGAACAAGTGCGCAGTGCTGCAGTCCAGCTTATCTGGGTCG
TCAGTCAGCTCTATCCTGAAAGCATTGTCCCAATTCCTTCTTCTAATGAAGAAATACGCTTAGTTGATGATGCGTTTGGCAAAATTTGTC
ACATGGTCAGTGATGGCTCTTGGGTGGTTCGTGTTCAGGCAGCAAAACTGTTGGGCTCTATGGAGCAAGTCAGTTCTCATTTCTTGGAGC
AGACCCTTGACAAGAAGCTGATGTCAGATCTGAGGAGGAAACGTACTGCACATGAGCGTGCCAAGGAACTTTACAGTTCGGGGGAGTTTT
CCAGTGGCAGAAAGTGGGGAGATGATGCTCCCAAGGAAGAAGTAGATACCGGGGCTGTGAACTTGATTGAGTCAGGAGCTTGTGGAGCTT
TTGTTCATGGGTTGGAAGATGAGATGTATGGTTTGAAATTGAAATTTCTTGATCCCAACAATATTCCCAAGGCCTCAATGACAAGTGGTT
TGGTTCAGCAGTTCCAACACACAGTCCTTCCCTCAGTGACTCCCTTGGCAACCCTCATCTGCACACTGATTGCCATATTGCCCTCTATTT
TCTGTCTTTGGTTTAAACCCCAAGGGCCCAGAGGCTTTCTCCGATGTCTAACTCTTTGTGCCTTGAGCTCCTTTATGTTTGGGTGGCATG
TTCATGAAAAAGCCATACTTCTAGCAATTCTCCCAATGAGCCTTTTGTCTGTGGGAAAAGCAGGAGACGCTTCGATTTTTCTGATTCTGA
CCACAACAGGACATTATTCCCTCTTTCCTCTGCTCTTCACTGCACCAGAACTTCCCATTAAAATCTTACTCATGTTACTATTCACCATAT
ATAGTATTTCGTCACTGAAGACTTTATTCAGACGGAGTTTCACCCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCTCAGCTAACTGA
AACCTCCGCCTCCCAGAAAAGAAAAACCTCTTTTTAATTGGATGGAAACTTTCTACCTGCTTGGCCTGGGGCCTCTGGAAGTCTGCTGTG
AATTTGTATTCCCTTTCACCTCCTGGAAGGTGAAGTACCCCTTCATCCCTTTGTTACTAACCTCAGTGTATTGTGCAGTAGGCATCACAT

>39941_39941_8_INTS4-ALG8_INTS4_chr11_77649697_ENST00000534064_ALG8_chr11_77820627_ENST00000376156_length(amino acids)=556AA_BP=388
MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRL
KIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSL
EKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPI
PSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPK
EEVDTGAVNLIESGACGAFVHGLEDEMYGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRG
FLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for INTS4-ALG8


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for INTS4-ALG8


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for INTS4-ALG8


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource