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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:IP6K2-COL7A1 (FusionGDB2 ID:40019)

Fusion Gene Summary for IP6K2-COL7A1

check button Fusion gene summary
Fusion gene informationFusion gene name: IP6K2-COL7A1
Fusion gene ID: 40019
HgeneTgene
Gene symbol

IP6K2

COL7A1

Gene ID

51447

1294

Gene nameinositol hexakisphosphate kinase 2collagen type VII alpha 1 chain
SynonymsIHPK2|InsP6K2|PIUSEBD1|EBDCT|EBR1|NDNC8
Cytomap

3p21.31

3p21.31

Type of geneprotein-codingprotein-coding
Descriptioninositol hexakisphosphate kinase 2ATP:1D-myo-inositol-hexakisphosphate phosphotransferaseinositol hexaphosphate kinase 2insp6 kinase 2pi uptake stimulatorcollagen alpha-1(VII) chainLC collagencollagen VII, alpha-1 polypeptidecollagen, type VII, alpha 1long-chain collagen
Modification date2020032720200329
UniProtAcc

Q9UHH9

Q02388

Ensembl transtripts involved in fusion geneENST00000431721, ENST00000443964, 
ENST00000446860, ENST00000450045, 
ENST00000436134, ENST00000328631, 
ENST00000340879, ENST00000413298, 
ENST00000417896, ENST00000432678, 
ENST00000449610, ENST00000453202, 
ENST00000470076, ENST00000328333, 
ENST00000454817, 
Fusion gene scores* DoF score13 X 12 X 7=10925 X 8 X 4=160
# samples 206
** MAII scorelog2(20/1092*10)=-2.44890095114513
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/160*10)=-1.41503749927884
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: IP6K2 [Title/Abstract] AND COL7A1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointIP6K2(48752822)-COL7A1(48623408), # samples:2
Anticipated loss of major functional domain due to fusion event.IP6K2-COL7A1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneIP6K2

GO:0043647

inositol phosphate metabolic process

30624931

HgeneIP6K2

GO:0046854

phosphatidylinositol phosphorylation

10574768


check buttonFusion gene breakpoints across IP6K2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across COL7A1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-23-1110-01AIP6K2chr3

48752748

-COL7A1chr3

48623408

-
ChimerDB4OVTCGA-23-1110-01AIP6K2chr3

48752822

-COL7A1chr3

48623408

-


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Fusion Gene ORF analysis for IP6K2-COL7A1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000431721ENST00000470076IP6K2chr3

48752748

-COL7A1chr3

48623408

-
5CDS-intronENST00000443964ENST00000470076IP6K2chr3

48752822

-COL7A1chr3

48623408

-
5CDS-intronENST00000446860ENST00000470076IP6K2chr3

48752822

-COL7A1chr3

48623408

-
5CDS-intronENST00000450045ENST00000470076IP6K2chr3

48752748

-COL7A1chr3

48623408

-
5UTR-3CDSENST00000436134ENST00000328333IP6K2chr3

48752748

-COL7A1chr3

48623408

-
5UTR-3CDSENST00000436134ENST00000454817IP6K2chr3

48752748

-COL7A1chr3

48623408

-
5UTR-intronENST00000436134ENST00000470076IP6K2chr3

48752748

-COL7A1chr3

48623408

-
Frame-shiftENST00000431721ENST00000328333IP6K2chr3

48752748

-COL7A1chr3

48623408

-
Frame-shiftENST00000431721ENST00000454817IP6K2chr3

48752748

-COL7A1chr3

48623408

-
Frame-shiftENST00000443964ENST00000328333IP6K2chr3

48752822

-COL7A1chr3

48623408

-
Frame-shiftENST00000443964ENST00000454817IP6K2chr3

48752822

-COL7A1chr3

48623408

-
Frame-shiftENST00000446860ENST00000328333IP6K2chr3

48752822

-COL7A1chr3

48623408

-
Frame-shiftENST00000446860ENST00000454817IP6K2chr3

48752822

-COL7A1chr3

48623408

-
In-frameENST00000450045ENST00000328333IP6K2chr3

48752748

-COL7A1chr3

48623408

-
In-frameENST00000450045ENST00000454817IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000328631ENST00000328333IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000328631ENST00000328333IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000328631ENST00000454817IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000328631ENST00000454817IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000340879ENST00000328333IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000340879ENST00000328333IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000340879ENST00000454817IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000340879ENST00000454817IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000413298ENST00000328333IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000413298ENST00000328333IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000413298ENST00000454817IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000413298ENST00000454817IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000417896ENST00000328333IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000417896ENST00000328333IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000417896ENST00000454817IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000417896ENST00000454817IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000431721ENST00000328333IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000431721ENST00000454817IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000432678ENST00000328333IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000432678ENST00000328333IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000432678ENST00000454817IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000432678ENST00000454817IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000436134ENST00000328333IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000436134ENST00000454817IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000443964ENST00000328333IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000443964ENST00000454817IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000446860ENST00000328333IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000446860ENST00000454817IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000449610ENST00000328333IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000449610ENST00000328333IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000449610ENST00000454817IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000449610ENST00000454817IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000450045ENST00000328333IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000450045ENST00000454817IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000453202ENST00000328333IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000453202ENST00000328333IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-3CDSENST00000453202ENST00000454817IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-3CDSENST00000453202ENST00000454817IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-intronENST00000328631ENST00000470076IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-intronENST00000328631ENST00000470076IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-intronENST00000340879ENST00000470076IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-intronENST00000340879ENST00000470076IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-intronENST00000413298ENST00000470076IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-intronENST00000413298ENST00000470076IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-intronENST00000417896ENST00000470076IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-intronENST00000417896ENST00000470076IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-intronENST00000431721ENST00000470076IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-intronENST00000432678ENST00000470076IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-intronENST00000432678ENST00000470076IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-intronENST00000436134ENST00000470076IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-intronENST00000443964ENST00000470076IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-intronENST00000446860ENST00000470076IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-intronENST00000449610ENST00000470076IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-intronENST00000449610ENST00000470076IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-intronENST00000450045ENST00000470076IP6K2chr3

48752822

-COL7A1chr3

48623408

-
intron-intronENST00000453202ENST00000470076IP6K2chr3

48752748

-COL7A1chr3

48623408

-
intron-intronENST00000453202ENST00000470076IP6K2chr3

48752822

-COL7A1chr3

48623408

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000450045IP6K2chr348752748-ENST00000454817COL7A1chr348623408-545210316351181651
ENST00000450045IP6K2chr348752748-ENST00000328333COL7A1chr348623408-554810316352141683

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000450045ENST00000454817IP6K2chr348752748-COL7A1chr348623408-0.0048185320.9951815
ENST00000450045ENST00000328333IP6K2chr348752748-COL7A1chr348623408-0.0048903130.9951096

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Fusion Genomic Features for IP6K2-COL7A1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for IP6K2-COL7A1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:48752822/chr3:48623408)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
IP6K2

Q9UHH9

COL7A1

Q02388

FUNCTION: Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). {ECO:0000269|PubMed:10574768, ECO:0000269|PubMed:30624931}.FUNCTION: Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000328333261182872_294412412945.0DomainBPTI/Kunitz inhibitor
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000454817261172872_294412412913.0DomainBPTI/Kunitz inhibitor
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000328333261181334_133612412945.0MotifCell attachment site
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000328333261182008_201012412945.0MotifCell attachment site
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000328333261182553_255512412945.0MotifCell attachment site
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000454817261171334_133612412913.0MotifCell attachment site
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000454817261172008_201012412913.0MotifCell attachment site
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000454817261172553_255512412913.0MotifCell attachment site
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000328333261181254_147712412945.0RegionNote=Interrupted collagenous region
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000328333261181254_278412412945.0RegionNote=Triple-helical region
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000328333261182785_294412412945.0RegionNote=Nonhelical region (NC2)
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000454817261171254_147712412913.0RegionNote=Interrupted collagenous region
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000454817261171254_278412412913.0RegionNote=Triple-helical region
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000454817261172785_294412412913.0RegionNote=Nonhelical region (NC2)

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIP6K2chr3:48752748chr3:48623408ENST00000328631-16207_2090427.0Nucleotide bindingATP
HgeneIP6K2chr3:48752748chr3:48623408ENST00000340879-13207_209098.0Nucleotide bindingATP
HgeneIP6K2chr3:48752748chr3:48623408ENST00000413298-14207_209098.0Nucleotide bindingATP
HgeneIP6K2chr3:48752748chr3:48623408ENST00000431721-23207_20911186.0Nucleotide bindingATP
HgeneIP6K2chr3:48752748chr3:48623408ENST00000432678-14207_2090221.66666666666666Nucleotide bindingATP
HgeneIP6K2chr3:48752748chr3:48623408ENST00000446860-13207_2090189.0Nucleotide bindingATP
HgeneIP6K2chr3:48752748chr3:48623408ENST00000328631-16236_2430427.0RegionSubstrate binding
HgeneIP6K2chr3:48752748chr3:48623408ENST00000340879-13236_243098.0RegionSubstrate binding
HgeneIP6K2chr3:48752748chr3:48623408ENST00000413298-14236_243098.0RegionSubstrate binding
HgeneIP6K2chr3:48752748chr3:48623408ENST00000431721-23236_24311186.0RegionSubstrate binding
HgeneIP6K2chr3:48752748chr3:48623408ENST00000432678-14236_2430221.66666666666666RegionSubstrate binding
HgeneIP6K2chr3:48752748chr3:48623408ENST00000446860-13236_2430189.0RegionSubstrate binding
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000328333261181054_122912412945.0DomainVWFA 2
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000032833326118234_32912412945.0DomainFibronectin type-III 1
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000032833326118330_41612412945.0DomainFibronectin type-III 2
TgeneCOL7A1chr3:48752748chr3:48623408ENST000003283332611838_21112412945.0DomainVWFA 1
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000032833326118417_50712412945.0DomainFibronectin type-III 3
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000032833326118510_59712412945.0DomainFibronectin type-III 4
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000032833326118600_68712412945.0DomainFibronectin type-III 5
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000032833326118688_77512412945.0DomainFibronectin type-III 6
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000032833326118778_86612412945.0DomainFibronectin type-III 7
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000032833326118869_95712412945.0DomainFibronectin type-III 8
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000032833326118958_105112412945.0DomainFibronectin type-III 9
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000454817261171054_122912412913.0DomainVWFA 2
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000045481726117234_32912412913.0DomainFibronectin type-III 1
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000045481726117330_41612412913.0DomainFibronectin type-III 2
TgeneCOL7A1chr3:48752748chr3:48623408ENST000004548172611738_21112412913.0DomainVWFA 1
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000045481726117417_50712412913.0DomainFibronectin type-III 3
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000045481726117510_59712412913.0DomainFibronectin type-III 4
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000045481726117600_68712412913.0DomainFibronectin type-III 5
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000045481726117688_77512412913.0DomainFibronectin type-III 6
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000045481726117778_86612412913.0DomainFibronectin type-III 7
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000045481726117869_95712412913.0DomainFibronectin type-III 8
TgeneCOL7A1chr3:48752748chr3:48623408ENST0000045481726117958_105112412913.0DomainFibronectin type-III 9
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000328333261181170_117212412945.0MotifCell attachment site
TgeneCOL7A1chr3:48752748chr3:48623408ENST00000454817261171170_117212412913.0MotifCell attachment site
TgeneCOL7A1chr3:48752748chr3:48623408ENST000003283332611817_125312412945.0RegionNote=Nonhelical region (NC1)
TgeneCOL7A1chr3:48752748chr3:48623408ENST000004548172611717_125312412913.0RegionNote=Nonhelical region (NC1)


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Fusion Gene Sequence for IP6K2-COL7A1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>40019_40019_1_IP6K2-COL7A1_IP6K2_chr3_48752748_ENST00000450045_COL7A1_chr3_48623408_ENST00000328333_length(transcript)=5548nt_BP=103nt
CCCTTCCAAGAGGGATGCCAGAGCCTTCTGTAAGCTCCTGAGATGTCACTGGTATCTAGGCAACAGGGATGAGCCTGAACCTCCCTGAGG
CCAGCTTACTGAGCCCCGGCCAGAGCCCTGCCCAGTGTATTGTCCAAAGGGCCAGAAGGGGGAACCTGGAGAGATGGGCCTGAGAGGACA
AGTTGGGCCTCCTGGCGACCCTGGCCTCCCGGGCAGGACCGGTGCTCCCGGCCCCCAGGGGCCCCCTGGAAGTGCCACTGCCAAGGGCGA
GAGGGGCTTCCCTGGAGCAGATGGGCGTCCAGGCAGCCCTGGCCGCGCCGGGAATCCTGGGACCCCTGGAGCCCCTGGCCTAAAGGGCTC
TCCAGGGTTGCCTGGCCCTCGTGGGGACCCGGGAGAGCGAGGACCTCGAGGCCCAAAGGGGGAGCCGGGGGCTCCCGGACAAGTCATCGG
AGGTGAAGGACCTGGGCTTCCTGGGCGGAAAGGGGACCCTGGACCATCGGGCCCCCCTGGACCTCGTGGACCACTGGGGGACCCAGGACC
CCGTGGCCCCCCAGGGCTTCCTGGAACAGCCATGAAGGGTGACAAAGGCGATCGTGGGGAGCGGGGTCCCCCTGGACCAGGTGAAGGTGG
CATTGCTCCTGGGGAGCCTGGGCTGCCGGGTCTTCCCGGAAGCCCTGGACCCCAAGGCCCCGTTGGCCCCCCTGGAAAGAAAGGAGAAAA
AGGTGACTCTGAGGATGGAGCTCCAGGCCTCCCAGGACAACCTGGGTCTCCGGGTGAGCAGGGCCCACGGGGACCTCCTGGAGCTATTGG
CCCCAAAGGTGACCGGGGCTTTCCAGGGCCCCTGGGTGAGGCTGGAGAGAAGGGCGAACGTGGACCCCCAGGCCCAGCGGGATCCCGGGG
GCTGCCAGGGGTTGCTGGACGTCCTGGAGCCAAGGGTCCTGAAGGGCCACCAGGACCCACTGGCCGCCAAGGAGAGAAGGGGGAGCCTGG
TCGCCCTGGGGACCCTGCAGTGGTGGGACCTGCTGTTGCTGGACCCAAAGGAGAAAAGGGAGATGTGGGGCCCGCTGGGCCCAGAGGAGC
TACCGGAGTCCAAGGGGAACGGGGCCCACCCGGCTTGGTTCTTCCTGGAGACCCTGGCCCCAAGGGAGACCCTGGAGACCGGGGTCCCAT
TGGCCTTACTGGCAGAGCAGGACCCCCAGGTGACTCAGGGCCTCCTGGAGAGAAGGGAGACCCTGGGCGGCCTGGCCCCCCAGGACCTGT
TGGCCCCCGAGGACGAGATGGTGAAGTTGGAGAGAAAGGTGACGAGGGTCCTCCGGGTGACCCGGGTTTGCCTGGAAAAGCAGGCGAGCG
TGGCCTTCGGGGGGCACCTGGAGTTCGGGGGCCTGTGGGTGAAAAGGGAGACCAGGGAGATCCTGGAGAGGATGGACGAAATGGCAGCCC
TGGATCATCTGGACCCAAGGGTGACCGTGGGGAGCCGGGTCCCCCAGGACCCCCGGGACGGCTGGTAGACACAGGACCTGGAGCCAGAGA
GAAGGGAGAGCCTGGGGACCGCGGACAAGAGGGTCCTCGAGGGCCCAAGGGTGATCCTGGCCTCCCTGGAGCCCCTGGGGAAAGGGGCAT
TGAAGGGTTTCGGGGACCCCCAGGCCCACAGGGGGACCCAGGTGTCCGAGGCCCAGCAGGAGAAAAGGGTGACCGGGGTCCCCCTGGGCT
GGATGGCCGGAGCGGACTGGATGGGAAACCAGGAGCCGCTGGGCCCTCTGGGCCGAATGGTGCTGCAGGCAAAGCTGGGGACCCAGGGAG
AGACGGGCTTCCAGGCCTCCGTGGAGAACAGGGCCTCCCTGGCCCCTCTGGTCCCCCTGGATTACCGGGAAAGCCAGGCGAGGATGGCAA
ACCTGGCCTGAATGGAAAAAACGGAGAACCTGGGGACCCTGGAGAAGACGGGAGGAAGGGAGAGAAAGGAGATTCAGGCGCCTCTGGGAG
AGAAGGTCGTGATGGCCCCAAGGGTGAGCGTGGAGCTCCTGGTATCCTTGGACCCCAGGGGCCTCCAGGCCTCCCAGGGCCAGTGGGCCC
TCCTGGCCAGGGTTTTCCTGGTGTCCCAGGAGGCACGGGCCCCAAGGGTGACCGTGGGGAGACTGGATCCAAAGGGGAGCAGGGCCTCCC
TGGAGAGCGTGGCCTGCGAGGAGAGCCTGGAAGTGTGCCGAATGTGGATCGGTTGCTGGAAACTGCTGGCATCAAGGCATCTGCCCTGCG
GGAGATCGTGGAGACCTGGGATGAGAGCTCTGGTAGCTTCCTGCCTGTGCCCGAACGGCGTCGAGGCCCCAAGGGGGACTCAGGCGAACA
GGGCCCCCCAGGCAAGGAGGGCCCCATCGGCTTTCCTGGAGAACGCGGGCTGAAGGGCGACCGTGGAGACCCTGGCCCTCAGGGGCCACC
TGGTCTGGCCCTTGGGGAGAGGGGCCCCCCCGGGCCTTCCGGCCTTGCCGGGGAGCCTGGAAAGCCTGGTATTCCCGGGCTCCCAGGCAG
GGCTGGGGGTGTGGGAGAGGCAGGAAGGCCAGGAGAGAGGGGAGAACGGGGAGAGAAAGGAGAACGTGGAGAACAGGGCAGAGATGGCCC
TCCTGGACTCCCTGGAACCCCTGGGCCCCCCGGACCCCCTGGCCCCAAGGTGTCTGTGGATGAGCCAGGTCCTGGACTCTCTGGAGAACA
GGGACCCCCTGGACTCAAGGGTGCTAAGGGGGAGCCGGGCAGCAATGGTGACCAAGGTCCCAAAGGAGACAGGGGTGTGCCAGGCATCAA
AGGAGACCGGGGAGAGCCTGGACCGAGGGGTCAGGACGGCAACCCGGGTCTACCAGGAGAGCGTGGTATGGCTGGGCCTGAAGGGAAGCC
GGGTCTGCAGGGTCCAAGAGGCCCCCCTGGCCCAGTGGGTGGTCATGGAGACCCTGGACCACCTGGTGCCCCGGGTCTTGCTGGCCCTGC
AGGACCCCAAGGACCTTCTGGCCTGAAGGGGGAGCCTGGAGAGACAGGACCTCCAGGACGGGGCCTGACTGGACCTACTGGAGCTGTGGG
ACTTCCTGGACCCCCCGGCCCTTCAGGCCTTGTGGGTCCACAGGGGTCTCCAGGTTTGCCTGGACAAGTGGGGGAGACAGGGAAGCCGGG
AGCCCCAGGTCGAGATGGTGCCAGTGGAAAAGATGGAGACAGAGGGAGCCCTGGTGTGCCAGGGTCACCAGGTCTGCCTGGCCCTGTCGG
ACCTAAAGGAGAACCTGGCCCCACGGGGGCCCCTGGACAGGCTGTGGTCGGGCTCCCTGGAGCAAAGGGAGAGAAGGGAGCCCCTGGAGG
CCTTGCTGGAGACCTGGTGGGTGAGCCGGGAGCCAAAGGTGACCGAGGACTGCCAGGGCCGCGAGGCGAGAAGGGTGAAGCTGGCCGTGC
AGGGGAGCCCGGAGACCCTGGGGAAGATGGTCAGAAAGGGGCTCCAGGACCCAAAGGTTTCAAGGGTGACCCAGGAGTCGGGGTCCCGGG
CTCCCCTGGGCCTCCTGGCCCTCCAGGTGTGAAGGGAGATCTGGGCCTCCCTGGCCTGCCCGGTGCTCCTGGTGTTGTTGGGTTCCCGGG
TCAGACAGGCCCTCGAGGAGAGATGGGTCAGCCAGGCCCTAGTGGAGAGCGGGGTCTGGCAGGCCCCCCAGGGAGAGAAGGAATCCCAGG
ACCCCTGGGGCCACCTGGACCACCGGGGTCAGTGGGACCACCTGGGGCCTCTGGACTCAAAGGAGACAAGGGAGACCCTGGAGTAGGGCT
GCCTGGGCCCCGAGGCGAGCGTGGGGAGCCAGGCATCCGGGGTGAAGATGGCCGCCCCGGCCAGGAGGGACCCCGAGGACTCACGGGGCC
CCCTGGCAGCAGGGGAGAGCGTGGGGAGAAGGGTGATGTTGGGAGTGCAGGACTAAAGGGTGACAAGGGAGACTCAGCTGTGATCCTGGG
GCCTCCAGGCCCACGGGGTGCCAAGGGGGACATGGGTGAACGAGGGCCTCGGGGCTTGGATGGTGACAAAGGACCTCGGGGAGACAATGG
GGACCCTGGTGACAAGGGCAGCAAGGGAGAGCCTGGTGACAAGGGCTCAGCCGGGTTGCCAGGACTGCGTGGACTCCTGGGACCCCAGGG
TCAACCTGGTGCAGCAGGGATCCCTGGTGACCCGGGATCCCCAGGAAAGGATGGAGTGCCTGGTATCCGAGGAGAAAAAGGAGATGTTGG
CTTCATGGGTCCCCGGGGCCTCAAGGGTGAACGGGGAGTGAAGGGAGCCTGTGGCCTTGATGGAGAGAAGGGAGACAAGGGAGAAGCTGG
TCCCCCAGGCCGCCCCGGGCTGGCAGGACACAAAGGAGAGATGGGGGAGCCTGGTGTGCCGGGCCAGTCGGGGGCCCCTGGCAAGGAGGG
CCTGATCGGTCCCAAGGGTGACCGAGGCTTTGACGGGCAGCCAGGCCCCAAGGGTGACCAGGGCGAGAAAGGGGAGCGGGGAACCCCAGG
AATTGGGGGCTTCCCAGGCCCCAGTGGAAATGATGGCTCTGCTGGTCCCCCAGGGCCACCTGGCAGTGTTGGTCCCAGAGGCCCCGAAGG
ACTTCAGGGCCAGAAGGGTGAGCGAGGTCCCCCCGGAGAGAGAGTGGTGGGGGCTCCTGGGGTCCCTGGAGCTCCTGGCGAGAGAGGGGA
GCAGGGGCGGCCAGGGCCTGCCGGTCCTCGAGGCGAGAAGGGAGAAGCTGCACTGACGGAGGATGACATCCGGGGCTTTGTGCGCCAAGA
GATGAGTCAGCACTGTGCCTGCCAGGGCCAGTTCATCGCATCTGGATCACGACCCCTCCCTAGTTATGCTGCAGACACTGCCGGCTCCCA
GCTCCATGCTGTGCCTGTGCTCCGCGTCTCTCATGCAGAGGAGGAAGAGCGGGTACCCCCTGAGGATGATGAGTACTCTGAATACTCCGA
GTATTCTGTGGAGGAGTACCAGGACCCTGAAGCTCCTTGGGATAGTGATGACCCCTGTTCCCTGCCACTGGATGAGGGCTCCTGCACTGC
CTACACCCTGCGCTGGTACCATCGGGCTGTGACAGGCAGCACAGAGGCCTGTCACCCTTTTGTCTATGGTGGCTGTGGAGGGAATGCCAA
CCGTTTTGGGACCCGTGAGGCCTGCGAGCGCCGCTGCCCACCCCGGGTGGTCCAGAGCCAGGGGACAGGTACTGCCCAGGACTGAGGCCC
AGATAATGAGCTGAGATTCAGCATCCCCTGGAGGAGTCGGGGTCTCAGCAGAACCCCACTGTCCCTCCCCTTGGTGCTAGAGGCTTGTGT
GCACGTGAGCGTGCGTGTGCACGTCCGTTATTTCAGTGACTTGGTCCCGTGGGTCTAGCCTTCCCCCCTGTGGACAAACCCCCATTGTGG
CTCCTGCCACCCTGGCAGATGACTCACTGTGGGGGGGTGGCTGTGGGCAGTGAGCGGATGTGACTGGCGTCTGACCCGCCCCTTGACCCA

>40019_40019_1_IP6K2-COL7A1_IP6K2_chr3_48752748_ENST00000450045_COL7A1_chr3_48623408_ENST00000328333_length(amino acids)=1683AA_BP=241
MGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGA
PGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPP
GKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQG
EKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRP
GPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDT
GPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGK
AGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGL
PGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPK
GDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGE
QGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMA
GPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVG
ETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEK
GEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPG
REGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGD
SAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRG
EKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKG
ERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIR
GFVRQEMSQHCACQGQFIASGSRPLPSYAADTAGSQLHAVPVLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEAPWDSDDPCSLPLD

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>40019_40019_2_IP6K2-COL7A1_IP6K2_chr3_48752748_ENST00000450045_COL7A1_chr3_48623408_ENST00000454817_length(transcript)=5452nt_BP=103nt
CCCTTCCAAGAGGGATGCCAGAGCCTTCTGTAAGCTCCTGAGATGTCACTGGTATCTAGGCAACAGGGATGAGCCTGAACCTCCCTGAGG
CCAGCTTACTGAGCCCCGGCCAGAGCCCTGCCCAGTGTATTGTCCAAAGGGCCAGAAGGGGGAACCTGGAGAGATGGGCCTGAGAGGACA
AGTTGGGCCTCCTGGCGACCCTGGCCTCCCGGGCAGGACCGGTGCTCCCGGCCCCCAGGGGCCCCCTGGAAGTGCCACTGCCAAGGGCGA
GAGGGGCTTCCCTGGAGCAGATGGGCGTCCAGGCAGCCCTGGCCGCGCCGGGAATCCTGGGACCCCTGGAGCCCCTGGCCTAAAGGGCTC
TCCAGGGTTGCCTGGCCCTCGTGGGGACCCGGGAGAGCGAGGACCTCGAGGCCCAAAGGGGGAGCCGGGGGCTCCCGGACAAGTCATCGG
AGGTGAAGGACCTGGGCTTCCTGGGCGGAAAGGGGACCCTGGACCATCGGGCCCCCCTGGACCTCGTGGACCACTGGGGGACCCAGGACC
CCGTGGCCCCCCAGGGCTTCCTGGAACAGCCATGAAGGGTGACAAAGGCGATCGTGGGGAGCGGGGTCCCCCTGGACCAGGTGAAGGTGG
CATTGCTCCTGGGGAGCCTGGGCTGCCGGGTCTTCCCGGAAGCCCTGGACCCCAAGGCCCCGTTGGCCCCCCTGGAAAGAAAGGAGAAAA
AGGTGACTCTGAGGATGGAGCTCCAGGCCTCCCAGGACAACCTGGGTCTCCGGGTGAGCAGGGCCCACGGGGACCTCCTGGAGCTATTGG
CCCCAAAGGTGACCGGGGCTTTCCAGGGCCCCTGGGTGAGGCTGGAGAGAAGGGCGAACGTGGACCCCCAGGCCCAGCGGGATCCCGGGG
GCTGCCAGGGGTTGCTGGACGTCCTGGAGCCAAGGGTCCTGAAGGGCCACCAGGACCCACTGGCCGCCAAGGAGAGAAGGGGGAGCCTGG
TCGCCCTGGGGACCCTGCAGTGGTGGGACCTGCTGTTGCTGGACCCAAAGGAGAAAAGGGAGATGTGGGGCCCGCTGGGCCCAGAGGAGC
TACCGGAGTCCAAGGGGAACGGGGCCCACCCGGCTTGGTTCTTCCTGGAGACCCTGGCCCCAAGGGAGACCCTGGAGACCGGGGTCCCAT
TGGCCTTACTGGCAGAGCAGGACCCCCAGGTGACTCAGGGCCTCCTGGAGAGAAGGGAGACCCTGGGCGGCCTGGCCCCCCAGGACCTGT
TGGCCCCCGAGGACGAGATGGTGAAGTTGGAGAGAAAGGTGACGAGGGTCCTCCGGGTGACCCGGGTTTGCCTGGAAAAGCAGGCGAGCG
TGGCCTTCGGGGGGCACCTGGAGTTCGGGGGCCTGTGGGTGAAAAGGGAGACCAGGGAGATCCTGGAGAGGATGGACGAAATGGCAGCCC
TGGATCATCTGGACCCAAGGGTGACCGTGGGGAGCCGGGTCCCCCAGGACCCCCGGGACGGCTGGTAGACACAGGACCTGGAGCCAGAGA
GAAGGGAGAGCCTGGGGACCGCGGACAAGAGGGTCCTCGAGGGCCCAAGGGTGATCCTGGCCTCCCTGGAGCCCCTGGGGAAAGGGGCAT
TGAAGGGTTTCGGGGACCCCCAGGCCCACAGGGGGACCCAGGTGTCCGAGGCCCAGCAGGAGAAAAGGGTGACCGGGGTCCCCCTGGGCT
GGATGGCCGGAGCGGACTGGATGGGAAACCAGGAGCCGCTGGGCCCTCTGGGCCGAATGGTGCTGCAGGCAAAGCTGGGGACCCAGGGAG
AGACGGGCTTCCAGGCCTCCGTGGAGAACAGGGCCTCCCTGGCCCCTCTGGTCCCCCTGGATTACCGGGAAAGCCAGGCGAGGATGGCAA
ACCTGGCCTGAATGGAAAAAACGGAGAACCTGGGGACCCTGGAGAAGACGGGAGGAAGGGAGAGAAAGGAGATTCAGGCGCCTCTGGGAG
AGAAGGTTTTCCTGGTGTCCCAGGAGGCACGGGCCCCAAGGGTGACCGTGGGGAGACTGGATCCAAAGGGGAGCAGGGCCTCCCTGGAGA
GCGTGGCCTGCGAGGAGAGCCTGGAAGTGTGCCGAATGTGGATCGGTTGCTGGAAACTGCTGGCATCAAGGCATCTGCCCTGCGGGAGAT
CGTGGAGACCTGGGATGAGAGCTCTGGTAGCTTCCTGCCTGTGCCCGAACGGCGTCGAGGCCCCAAGGGGGACTCAGGCGAACAGGGCCC
CCCAGGCAAGGAGGGCCCCATCGGCTTTCCTGGAGAACGCGGGCTGAAGGGCGACCGTGGAGACCCTGGCCCTCAGGGGCCACCTGGTCT
GGCCCTTGGGGAGAGGGGCCCCCCCGGGCCTTCCGGCCTTGCCGGGGAGCCTGGAAAGCCTGGTATTCCCGGGCTCCCAGGCAGGGCTGG
GGGTGTGGGAGAGGCAGGAAGGCCAGGAGAGAGGGGAGAACGGGGAGAGAAAGGAGAACGTGGAGAACAGGGCAGAGATGGCCCTCCTGG
ACTCCCTGGAACCCCTGGGCCCCCCGGACCCCCTGGCCCCAAGGTGTCTGTGGATGAGCCAGGTCCTGGACTCTCTGGAGAACAGGGACC
CCCTGGACTCAAGGGTGCTAAGGGGGAGCCGGGCAGCAATGGTGACCAAGGTCCCAAAGGAGACAGGGGTGTGCCAGGCATCAAAGGAGA
CCGGGGAGAGCCTGGACCGAGGGGTCAGGACGGCAACCCGGGTCTACCAGGAGAGCGTGGTATGGCTGGGCCTGAAGGGAAGCCGGGTCT
GCAGGGTCCAAGAGGCCCCCCTGGCCCAGTGGGTGGTCATGGAGACCCTGGACCACCTGGTGCCCCGGGTCTTGCTGGCCCTGCAGGACC
CCAAGGACCTTCTGGCCTGAAGGGGGAGCCTGGAGAGACAGGACCTCCAGGACGGGGCCTGACTGGACCTACTGGAGCTGTGGGACTTCC
TGGACCCCCCGGCCCTTCAGGCCTTGTGGGTCCACAGGGGTCTCCAGGTTTGCCTGGACAAGTGGGGGAGACAGGGAAGCCGGGAGCCCC
AGGTCGAGATGGTGCCAGTGGAAAAGATGGAGACAGAGGGAGCCCTGGTGTGCCAGGGTCACCAGGTCTGCCTGGCCCTGTCGGACCTAA
AGGAGAACCTGGCCCCACGGGGGCCCCTGGACAGGCTGTGGTCGGGCTCCCTGGAGCAAAGGGAGAGAAGGGAGCCCCTGGAGGCCTTGC
TGGAGACCTGGTGGGTGAGCCGGGAGCCAAAGGTGACCGAGGACTGCCAGGGCCGCGAGGCGAGAAGGGTGAAGCTGGCCGTGCAGGGGA
GCCCGGAGACCCTGGGGAAGATGGTCAGAAAGGGGCTCCAGGACCCAAAGGTTTCAAGGGTGACCCAGGAGTCGGGGTCCCGGGCTCCCC
TGGGCCTCCTGGCCCTCCAGGTGTGAAGGGAGATCTGGGCCTCCCTGGCCTGCCCGGTGCTCCTGGTGTTGTTGGGTTCCCGGGTCAGAC
AGGCCCTCGAGGAGAGATGGGTCAGCCAGGCCCTAGTGGAGAGCGGGGTCTGGCAGGCCCCCCAGGGAGAGAAGGAATCCCAGGACCCCT
GGGGCCACCTGGACCACCGGGGTCAGTGGGACCACCTGGGGCCTCTGGACTCAAAGGAGACAAGGGAGACCCTGGAGTAGGGCTGCCTGG
GCCCCGAGGCGAGCGTGGGGAGCCAGGCATCCGGGGTGAAGATGGCCGCCCCGGCCAGGAGGGACCCCGAGGACTCACGGGGCCCCCTGG
CAGCAGGGGAGAGCGTGGGGAGAAGGGTGATGTTGGGAGTGCAGGACTAAAGGGTGACAAGGGAGACTCAGCTGTGATCCTGGGGCCTCC
AGGCCCACGGGGTGCCAAGGGGGACATGGGTGAACGAGGGCCTCGGGGCTTGGATGGTGACAAAGGACCTCGGGGAGACAATGGGGACCC
TGGTGACAAGGGCAGCAAGGGAGAGCCTGGTGACAAGGGCTCAGCCGGGTTGCCAGGACTGCGTGGACTCCTGGGACCCCAGGGTCAACC
TGGTGCAGCAGGGATCCCTGGTGACCCGGGATCCCCAGGAAAGGATGGAGTGCCTGGTATCCGAGGAGAAAAAGGAGATGTTGGCTTCAT
GGGTCCCCGGGGCCTCAAGGGTGAACGGGGAGTGAAGGGAGCCTGTGGCCTTGATGGAGAGAAGGGAGACAAGGGAGAAGCTGGTCCCCC
AGGCCGCCCCGGGCTGGCAGGACACAAAGGAGAGATGGGGGAGCCTGGTGTGCCGGGCCAGTCGGGGGCCCCTGGCAAGGAGGGCCTGAT
CGGTCCCAAGGGTGACCGAGGCTTTGACGGGCAGCCAGGCCCCAAGGGTGACCAGGGCGAGAAAGGGGAGCGGGGAACCCCAGGAATTGG
GGGCTTCCCAGGCCCCAGTGGAAATGATGGCTCTGCTGGTCCCCCAGGGCCACCTGGCAGTGTTGGTCCCAGAGGCCCCGAAGGACTTCA
GGGCCAGAAGGGTGAGCGAGGTCCCCCCGGAGAGAGAGTGGTGGGGGCTCCTGGGGTCCCTGGAGCTCCTGGCGAGAGAGGGGAGCAGGG
GCGGCCAGGGCCTGCCGGTCCTCGAGGCGAGAAGGGAGAAGCTGCACTGACGGAGGATGACATCCGGGGCTTTGTGCGCCAAGAGATGAG
TCAGCACTGTGCCTGCCAGGGCCAGTTCATCGCATCTGGATCACGACCCCTCCCTAGTTATGCTGCAGACACTGCCGGCTCCCAGCTCCA
TGCTGTGCCTGTGCTCCGCGTCTCTCATGCAGAGGAGGAAGAGCGGGTACCCCCTGAGGATGATGAGTACTCTGAATACTCCGAGTATTC
TGTGGAGGAGTACCAGGACCCTGAAGCTCCTTGGGATAGTGATGACCCCTGTTCCCTGCCACTGGATGAGGGCTCCTGCACTGCCTACAC
CCTGCGCTGGTACCATCGGGCTGTGACAGGCAGCACAGAGGCCTGTCACCCTTTTGTCTATGGTGGCTGTGGAGGGAATGCCAACCGTTT
TGGGACCCGTGAGGCCTGCGAGCGCCGCTGCCCACCCCGGGTGGTCCAGAGCCAGGGGACAGGTACTGCCCAGGACTGAGGCCCAGATAA
TGAGCTGAGATTCAGCATCCCCTGGAGGAGTCGGGGTCTCAGCAGAACCCCACTGTCCCTCCCCTTGGTGCTAGAGGCTTGTGTGCACGT
GAGCGTGCGTGTGCACGTCCGTTATTTCAGTGACTTGGTCCCGTGGGTCTAGCCTTCCCCCCTGTGGACAAACCCCCATTGTGGCTCCTG
CCACCCTGGCAGATGACTCACTGTGGGGGGGTGGCTGTGGGCAGTGAGCGGATGTGACTGGCGTCTGACCCGCCCCTTGACCCAAGCCTG

>40019_40019_2_IP6K2-COL7A1_IP6K2_chr3_48752748_ENST00000450045_COL7A1_chr3_48623408_ENST00000454817_length(amino acids)=1651AA_BP=45
MGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGA
PGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPP
GKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQG
EKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRP
GPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDT
GPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGK
AGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGFPGVPGGTGPKGDRGETGSKGE
QGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGP
QGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGL
SGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGL
AGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLP
GPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGV
GVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDP
GVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPR
GDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDK
GEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPR
GPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLPSYAADT
AGSQLHAVPVLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEAPWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCG

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Fusion Gene PPI Analysis for IP6K2-COL7A1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for IP6K2-COL7A1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for IP6K2-COL7A1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource