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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:IPO11-TNFAIP8 (FusionGDB2 ID:40050)

Fusion Gene Summary for IPO11-TNFAIP8

check button Fusion gene summary
Fusion gene informationFusion gene name: IPO11-TNFAIP8
Fusion gene ID: 40050
HgeneTgene
Gene symbol

IPO11

TNFAIP8

Gene ID

51194

25816

Gene nameimportin 11TNF alpha induced protein 8
SynonymsRanBP11GG2-1|MDC-3.13|NDED|SCC-S2|SCCS2
Cytomap

5q12.1

5q23.1

Type of geneprotein-codingprotein-coding
Descriptionimportin-11Ran binding protein 11imp11ran-binding protein 11tumor necrosis factor alpha-induced protein 8NF-kappa-B-inducible DED-containing proteinTNF-induced protein GG2-1head and neck tumor and metastasis-related proteintumor necrosis factor, alpha induced protein 8
Modification date2020031320200313
UniProtAcc

Q9UI26

.
Ensembl transtripts involved in fusion geneENST00000325324, ENST00000409296, 
ENST00000409534, ENST00000512177, 
ENST00000415806, ENST00000274456, 
ENST00000504771, ENST00000503646, 
ENST00000504642, ENST00000513374, 
Fusion gene scores* DoF score11 X 9 X 4=3968 X 5 X 5=200
# samples 1211
** MAII scorelog2(12/396*10)=-1.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/200*10)=-0.862496476250065
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: IPO11 [Title/Abstract] AND TNFAIP8 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointIPO11(61770291)-TNFAIP8(118728511), # samples:3
Anticipated loss of major functional domain due to fusion event.IPO11-TNFAIP8 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across IPO11 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TNFAIP8 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A08L-01AIPO11chr5

61770291

-TNFAIP8chr5

118728511

+
ChimerDB4BRCATCGA-A8-A08L-01AIPO11chr5

61770291

+TNFAIP8chr5

118728511

+
ChimerDB4BRCATCGA-A8-A08LIPO11chr5

61770291

+TNFAIP8chr5

118728510

+


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Fusion Gene ORF analysis for IPO11-TNFAIP8

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000325324ENST00000415806IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
5CDS-3UTRENST00000325324ENST00000415806IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
5CDS-3UTRENST00000409296ENST00000415806IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
5CDS-3UTRENST00000409296ENST00000415806IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
Frame-shiftENST00000325324ENST00000274456IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
Frame-shiftENST00000325324ENST00000274456IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
Frame-shiftENST00000325324ENST00000504771IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
Frame-shiftENST00000325324ENST00000504771IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
Frame-shiftENST00000409296ENST00000274456IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
Frame-shiftENST00000409296ENST00000274456IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
Frame-shiftENST00000409296ENST00000504771IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
Frame-shiftENST00000409296ENST00000504771IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
In-frameENST00000325324ENST00000503646IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
In-frameENST00000325324ENST00000503646IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
In-frameENST00000325324ENST00000504642IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
In-frameENST00000325324ENST00000504642IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
In-frameENST00000325324ENST00000513374IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
In-frameENST00000325324ENST00000513374IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
In-frameENST00000409296ENST00000503646IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
In-frameENST00000409296ENST00000503646IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
In-frameENST00000409296ENST00000504642IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
In-frameENST00000409296ENST00000504642IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
In-frameENST00000409296ENST00000513374IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
In-frameENST00000409296ENST00000513374IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
intron-3CDSENST00000409534ENST00000274456IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
intron-3CDSENST00000409534ENST00000274456IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
intron-3CDSENST00000409534ENST00000503646IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
intron-3CDSENST00000409534ENST00000503646IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
intron-3CDSENST00000409534ENST00000504642IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
intron-3CDSENST00000409534ENST00000504642IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
intron-3CDSENST00000409534ENST00000504771IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
intron-3CDSENST00000409534ENST00000504771IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
intron-3CDSENST00000409534ENST00000513374IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
intron-3CDSENST00000409534ENST00000513374IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
intron-3CDSENST00000512177ENST00000274456IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
intron-3CDSENST00000512177ENST00000274456IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
intron-3CDSENST00000512177ENST00000503646IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
intron-3CDSENST00000512177ENST00000503646IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
intron-3CDSENST00000512177ENST00000504642IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
intron-3CDSENST00000512177ENST00000504642IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
intron-3CDSENST00000512177ENST00000504771IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
intron-3CDSENST00000512177ENST00000504771IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
intron-3CDSENST00000512177ENST00000513374IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
intron-3CDSENST00000512177ENST00000513374IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
intron-3UTRENST00000409534ENST00000415806IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
intron-3UTRENST00000409534ENST00000415806IPO11chr5

61770291

+TNFAIP8chr5

118728510

+
intron-3UTRENST00000512177ENST00000415806IPO11chr5

61770291

+TNFAIP8chr5

118728511

+
intron-3UTRENST00000512177ENST00000415806IPO11chr5

61770291

+TNFAIP8chr5

118728510

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000325324IPO11chr561770291+ENST00000513374TNFAIP8chr5118728511+1854926731491472
ENST00000325324IPO11chr561770291+ENST00000503646TNFAIP8chr5118728511+2709926731491472
ENST00000325324IPO11chr561770291+ENST00000504642TNFAIP8chr5118728511+1557926731491472
ENST00000409296IPO11chr561770291+ENST00000513374TNFAIP8chr5118728511+193510071301572480
ENST00000409296IPO11chr561770291+ENST00000503646TNFAIP8chr5118728511+279010071301572480
ENST00000409296IPO11chr561770291+ENST00000504642TNFAIP8chr5118728511+163810071301572480
ENST00000325324IPO11chr561770291+ENST00000513374TNFAIP8chr5118728510+1854926731491472
ENST00000325324IPO11chr561770291+ENST00000503646TNFAIP8chr5118728510+2709926731491472
ENST00000325324IPO11chr561770291+ENST00000504642TNFAIP8chr5118728510+1557926731491472
ENST00000409296IPO11chr561770291+ENST00000513374TNFAIP8chr5118728510+193510071301572480
ENST00000409296IPO11chr561770291+ENST00000503646TNFAIP8chr5118728510+279010071301572480
ENST00000409296IPO11chr561770291+ENST00000504642TNFAIP8chr5118728510+163810071301572480

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000325324ENST00000513374IPO11chr561770291+TNFAIP8chr5118728511+0.0007332470.9992668
ENST00000325324ENST00000503646IPO11chr561770291+TNFAIP8chr5118728511+0.0002848340.99971515
ENST00000325324ENST00000504642IPO11chr561770291+TNFAIP8chr5118728511+0.0014430190.99855703
ENST00000409296ENST00000513374IPO11chr561770291+TNFAIP8chr5118728511+0.0007684740.9992316
ENST00000409296ENST00000503646IPO11chr561770291+TNFAIP8chr5118728511+0.0002695330.9997304
ENST00000409296ENST00000504642IPO11chr561770291+TNFAIP8chr5118728511+0.0015804720.9984195
ENST00000325324ENST00000513374IPO11chr561770291+TNFAIP8chr5118728510+0.0007332470.9992668
ENST00000325324ENST00000503646IPO11chr561770291+TNFAIP8chr5118728510+0.0002848340.99971515
ENST00000325324ENST00000504642IPO11chr561770291+TNFAIP8chr5118728510+0.0014430190.99855703
ENST00000409296ENST00000513374IPO11chr561770291+TNFAIP8chr5118728510+0.0007684740.9992316
ENST00000409296ENST00000503646IPO11chr561770291+TNFAIP8chr5118728510+0.0002695330.9997304
ENST00000409296ENST00000504642IPO11chr561770291+TNFAIP8chr5118728510+0.0015804720.9984195

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Fusion Genomic Features for IPO11-TNFAIP8


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
IPO11chr561770291+TNFAIP8chr5118728510+6.64E-091
IPO11chr561770291+TNFAIP8chr5118728510+6.64E-091
IPO11chr561770291+TNFAIP8chr5118728510+6.64E-091
IPO11chr561770291+TNFAIP8chr5118728510+6.64E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for IPO11-TNFAIP8


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:61770291/chr5:118728511)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
IPO11

Q9UI26

.
FUNCTION: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of UBE2E3, and of RPL12 (By similarity). {ECO:0000250, ECO:0000269|PubMed:11032817}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+83028_100252976.0DomainImportin N-terminal
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+83028_1002921016.0DomainImportin N-terminal
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+83028_100252976.0DomainImportin N-terminal
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+83028_1002921016.0DomainImportin N-terminal
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830123_160252976.0RepeatNote=HEAT 1
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830209_248252976.0RepeatNote=HEAT 2
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830123_1602921016.0RepeatNote=HEAT 1
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830209_2482921016.0RepeatNote=HEAT 2
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830123_160252976.0RepeatNote=HEAT 1
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830209_248252976.0RepeatNote=HEAT 2
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830123_1602921016.0RepeatNote=HEAT 1
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830209_2482921016.0RepeatNote=HEAT 2
TgeneTNFAIP8chr5:61770291chr5:118728510ENST000002744560249_830189.0Coiled coilOntology_term=ECO:0000255
TgeneTNFAIP8chr5:61770291chr5:118728510ENST000005036461349_8310199.0Coiled coilOntology_term=ECO:0000255
TgeneTNFAIP8chr5:61770291chr5:118728510ENST000005047710249_8310199.0Coiled coilOntology_term=ECO:0000255
TgeneTNFAIP8chr5:61770291chr5:118728511ENST000002744560249_830189.0Coiled coilOntology_term=ECO:0000255
TgeneTNFAIP8chr5:61770291chr5:118728511ENST000005036461349_8310199.0Coiled coilOntology_term=ECO:0000255
TgeneTNFAIP8chr5:61770291chr5:118728511ENST000005047710249_8310199.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830318_356252976.0RepeatNote=HEAT 3
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830422_459252976.0RepeatNote=HEAT 4
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830473_509252976.0RepeatNote=HEAT 5
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830511_548252976.0RepeatNote=HEAT 6
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830555_593252976.0RepeatNote=HEAT 7
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830600_636252976.0RepeatNote=HEAT 8
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830640_677252976.0RepeatNote=HEAT 9
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830683_720252976.0RepeatNote=HEAT 10
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830743_764252976.0RepeatNote=HEAT 11
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830765_804252976.0RepeatNote=HEAT 12
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830819_849252976.0RepeatNote=HEAT 13
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830850_887252976.0RepeatNote=HEAT 14
HgeneIPO11chr5:61770291chr5:118728510ENST00000325324+830957_974252976.0RepeatNote=HEAT 15
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830318_3562921016.0RepeatNote=HEAT 3
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830422_4592921016.0RepeatNote=HEAT 4
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830473_5092921016.0RepeatNote=HEAT 5
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830511_5482921016.0RepeatNote=HEAT 6
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830555_5932921016.0RepeatNote=HEAT 7
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830600_6362921016.0RepeatNote=HEAT 8
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830640_6772921016.0RepeatNote=HEAT 9
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830683_7202921016.0RepeatNote=HEAT 10
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830743_7642921016.0RepeatNote=HEAT 11
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830765_8042921016.0RepeatNote=HEAT 12
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830819_8492921016.0RepeatNote=HEAT 13
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830850_8872921016.0RepeatNote=HEAT 14
HgeneIPO11chr5:61770291chr5:118728510ENST00000409296+830957_9742921016.0RepeatNote=HEAT 15
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830318_356252976.0RepeatNote=HEAT 3
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830422_459252976.0RepeatNote=HEAT 4
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830473_509252976.0RepeatNote=HEAT 5
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830511_548252976.0RepeatNote=HEAT 6
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830555_593252976.0RepeatNote=HEAT 7
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830600_636252976.0RepeatNote=HEAT 8
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830640_677252976.0RepeatNote=HEAT 9
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830683_720252976.0RepeatNote=HEAT 10
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830743_764252976.0RepeatNote=HEAT 11
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830765_804252976.0RepeatNote=HEAT 12
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830819_849252976.0RepeatNote=HEAT 13
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830850_887252976.0RepeatNote=HEAT 14
HgeneIPO11chr5:61770291chr5:118728511ENST00000325324+830957_974252976.0RepeatNote=HEAT 15
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830318_3562921016.0RepeatNote=HEAT 3
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830422_4592921016.0RepeatNote=HEAT 4
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830473_5092921016.0RepeatNote=HEAT 5
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830511_5482921016.0RepeatNote=HEAT 6
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830555_5932921016.0RepeatNote=HEAT 7
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830600_6362921016.0RepeatNote=HEAT 8
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830640_6772921016.0RepeatNote=HEAT 9
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830683_7202921016.0RepeatNote=HEAT 10
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830743_7642921016.0RepeatNote=HEAT 11
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830765_8042921016.0RepeatNote=HEAT 12
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830819_8492921016.0RepeatNote=HEAT 13
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830850_8872921016.0RepeatNote=HEAT 14
HgeneIPO11chr5:61770291chr5:118728511ENST00000409296+830957_9742921016.0RepeatNote=HEAT 15


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Fusion Gene Sequence for IPO11-TNFAIP8


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>40050_40050_1_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000325324_TNFAIP8_chr5_118728510_ENST00000503646_length(transcript)=2709nt_BP=926nt
TTTGGAGCTGCGACGCCAAACATGGCGTGTTCCTAGAAGCCGCTTTCGGCATCAGTAGGCGGCGGCGTGGGGTCTGGCAGCGTGGGGAGA
GGGACCAACCGACGCCACTTCGTGTTGGGAAGTGGGAGCGGGAGGGCCGGGCAATTCCCGACCGAACCAAACGGTTTCCATGGATCTCAA
TAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCA
GTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACT
GTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCT
CATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACA
GTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGT
TACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCT
GTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATC
ATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGA
ACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAA
AATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACAC
CCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAA
TCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATAC
CTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACA
TGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTT
ACAAAAACTATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTT
GAAGATGGAGCACTGCTGATTTATGAAGGAAAAAAGAAGAATTTTCTAAAGATTACACATATTTCAGAAAGACTTTACCCAATTCAGTTG
TCAGACATAATGATTTATTTGAAGGCTTGTTTTATTTGAAGAAAAGCATATTGCCAAAAATTCTGGTTAAAAGCTTCCTAACGGGTAACA
GACCATGGGAGAGATATGTGGTTGGGTAATGCAAATGTAGTTATACAAAGAAAAATACAGATGTCTCCAGACCTGAGGACTTTTTAATAG
GGCAGTTGTTGTGTTGGTGGCACATTGGATATTTCTAACATGTACAAAGCTATGTATTTTGATTTACTTTCATTTCTTGCTATGTATATG
TACTTTTCTTAAAATGCCAAGAACTTTCTCTTGCTATCATTGCTCCTTTTGAAACAATTCAATTTTCATGTCTACAGCTGACTGTTTTGT
TAAGATTGAGTCATCGACATTCAGGATTTAAGTCTGAGGTAGTCAACCCTCAGGAAAAAAAAAATGGCTTATCTGAAATCAGTACTGTGG
AAATGAACTATATTAGCTATTATGAATAATGTCCAGTATAAGAATATGCTTCTGGAATTGAGTTCTCCTTTTAAGTACCAATGATACTTA
AATTTCTCAGAAATGTAATGGTGTGTCATTGCCTTGAAATGCTTGCTTAGGGCTTCTTTTATGTTATCTTAAAAAGTGCTGGTGAATTTT
CCATTTTTTACATCCATTTCACATGTAAGAGACAAAAAAGTCTAGATTGGTCTTGATATTGAGATAATAAAAAGTAAGTAGCATTAAGAA
AGGTAACAATCTTCATTCTACAGATGAACTCATTGAAACAATTTAGGGGAATGAGGGGCAAAAGGGGAGAAATACTGCTAAAGAACATGA
GCATAAAAATGCGTGCGTTTCAGTGTTTAAGAAGGCTTGATAAAGAATGTCACTTTTTTATTTAACTGATAAGATTTTTGTTATTTTTTA
CTTTGATAAGTAAACCAAAGAATATTTGTATTTCAAGCAGTTTGTGTGGTGTTTCTATATAATTTTCTGTGTATAAATAATAAAGTAGGC
ATTTGTTTATTTTGTAAAAAAGAAATGAAAATCTGCTGGCCAGCTATGTCCTCTAGGAAATGACAGACCCAACCACCAGCAATAAACATT

>40050_40050_1_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000325324_TNFAIP8_chr5_118728510_ENST00000503646_length(amino acids)=472AA_BP=285
MAAWGEGPTDATSCWEVGAGGPGNSRPNQTVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINV
RWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQDDLRQHRAL
LTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGF
LHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILY
RNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFG

--------------------------------------------------------------
>40050_40050_2_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000325324_TNFAIP8_chr5_118728510_ENST00000504642_length(transcript)=1557nt_BP=926nt
TTTGGAGCTGCGACGCCAAACATGGCGTGTTCCTAGAAGCCGCTTTCGGCATCAGTAGGCGGCGGCGTGGGGTCTGGCAGCGTGGGGAGA
GGGACCAACCGACGCCACTTCGTGTTGGGAAGTGGGAGCGGGAGGGCCGGGCAATTCCCGACCGAACCAAACGGTTTCCATGGATCTCAA
TAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCA
GTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACT
GTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCT
CATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACA
GTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGT
TACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCT
GTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATC
ATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGA
ACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAA
AATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACAC
CCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAA
TCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATAC
CTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACA
TGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTT
ACAAAAACTATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTT

>40050_40050_2_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000325324_TNFAIP8_chr5_118728510_ENST00000504642_length(amino acids)=472AA_BP=285
MAAWGEGPTDATSCWEVGAGGPGNSRPNQTVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINV
RWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQDDLRQHRAL
LTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGF
LHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILY
RNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFG

--------------------------------------------------------------
>40050_40050_3_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000325324_TNFAIP8_chr5_118728510_ENST00000513374_length(transcript)=1854nt_BP=926nt
TTTGGAGCTGCGACGCCAAACATGGCGTGTTCCTAGAAGCCGCTTTCGGCATCAGTAGGCGGCGGCGTGGGGTCTGGCAGCGTGGGGAGA
GGGACCAACCGACGCCACTTCGTGTTGGGAAGTGGGAGCGGGAGGGCCGGGCAATTCCCGACCGAACCAAACGGTTTCCATGGATCTCAA
TAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCA
GTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACT
GTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCT
CATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACA
GTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGT
TACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCT
GTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATC
ATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGA
ACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAA
AATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACAC
CCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAA
TCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATAC
CTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACA
TGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTT
ACAAAAACTATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTT
GAAGATGGAGCACTGCTGATTTATGAAGGAAAAAAGAAGAATTTTCTAAAGATTACACATATTTCAGAAAGACTTTACCCAATTCAGTTG
TCAGACATAATGATTTATTTGAAGGCTTGTTTTATTTGAAGAAAAGCATATTGCCAAAAATTCTGGTTAAAAGCTTCCTAACGGGTAACA
GACCATGGGAGAGATATGTGGTTGGGTAATGCAAATGTAGTTATACAAAGAAAAATACAGATGTCTCCAGACCTGAGGACTTTTTAATAG

>40050_40050_3_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000325324_TNFAIP8_chr5_118728510_ENST00000513374_length(amino acids)=472AA_BP=285
MAAWGEGPTDATSCWEVGAGGPGNSRPNQTVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINV
RWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQDDLRQHRAL
LTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGF
LHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILY
RNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFG

--------------------------------------------------------------
>40050_40050_4_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000325324_TNFAIP8_chr5_118728511_ENST00000503646_length(transcript)=2709nt_BP=926nt
TTTGGAGCTGCGACGCCAAACATGGCGTGTTCCTAGAAGCCGCTTTCGGCATCAGTAGGCGGCGGCGTGGGGTCTGGCAGCGTGGGGAGA
GGGACCAACCGACGCCACTTCGTGTTGGGAAGTGGGAGCGGGAGGGCCGGGCAATTCCCGACCGAACCAAACGGTTTCCATGGATCTCAA
TAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCA
GTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACT
GTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCT
CATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACA
GTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGT
TACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCT
GTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATC
ATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGA
ACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAA
AATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACAC
CCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAA
TCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATAC
CTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACA
TGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTT
ACAAAAACTATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTT
GAAGATGGAGCACTGCTGATTTATGAAGGAAAAAAGAAGAATTTTCTAAAGATTACACATATTTCAGAAAGACTTTACCCAATTCAGTTG
TCAGACATAATGATTTATTTGAAGGCTTGTTTTATTTGAAGAAAAGCATATTGCCAAAAATTCTGGTTAAAAGCTTCCTAACGGGTAACA
GACCATGGGAGAGATATGTGGTTGGGTAATGCAAATGTAGTTATACAAAGAAAAATACAGATGTCTCCAGACCTGAGGACTTTTTAATAG
GGCAGTTGTTGTGTTGGTGGCACATTGGATATTTCTAACATGTACAAAGCTATGTATTTTGATTTACTTTCATTTCTTGCTATGTATATG
TACTTTTCTTAAAATGCCAAGAACTTTCTCTTGCTATCATTGCTCCTTTTGAAACAATTCAATTTTCATGTCTACAGCTGACTGTTTTGT
TAAGATTGAGTCATCGACATTCAGGATTTAAGTCTGAGGTAGTCAACCCTCAGGAAAAAAAAAATGGCTTATCTGAAATCAGTACTGTGG
AAATGAACTATATTAGCTATTATGAATAATGTCCAGTATAAGAATATGCTTCTGGAATTGAGTTCTCCTTTTAAGTACCAATGATACTTA
AATTTCTCAGAAATGTAATGGTGTGTCATTGCCTTGAAATGCTTGCTTAGGGCTTCTTTTATGTTATCTTAAAAAGTGCTGGTGAATTTT
CCATTTTTTACATCCATTTCACATGTAAGAGACAAAAAAGTCTAGATTGGTCTTGATATTGAGATAATAAAAAGTAAGTAGCATTAAGAA
AGGTAACAATCTTCATTCTACAGATGAACTCATTGAAACAATTTAGGGGAATGAGGGGCAAAAGGGGAGAAATACTGCTAAAGAACATGA
GCATAAAAATGCGTGCGTTTCAGTGTTTAAGAAGGCTTGATAAAGAATGTCACTTTTTTATTTAACTGATAAGATTTTTGTTATTTTTTA
CTTTGATAAGTAAACCAAAGAATATTTGTATTTCAAGCAGTTTGTGTGGTGTTTCTATATAATTTTCTGTGTATAAATAATAAAGTAGGC
ATTTGTTTATTTTGTAAAAAAGAAATGAAAATCTGCTGGCCAGCTATGTCCTCTAGGAAATGACAGACCCAACCACCAGCAATAAACATT

>40050_40050_4_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000325324_TNFAIP8_chr5_118728511_ENST00000503646_length(amino acids)=472AA_BP=285
MAAWGEGPTDATSCWEVGAGGPGNSRPNQTVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINV
RWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQDDLRQHRAL
LTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGF
LHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILY
RNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFG

--------------------------------------------------------------
>40050_40050_5_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000325324_TNFAIP8_chr5_118728511_ENST00000504642_length(transcript)=1557nt_BP=926nt
TTTGGAGCTGCGACGCCAAACATGGCGTGTTCCTAGAAGCCGCTTTCGGCATCAGTAGGCGGCGGCGTGGGGTCTGGCAGCGTGGGGAGA
GGGACCAACCGACGCCACTTCGTGTTGGGAAGTGGGAGCGGGAGGGCCGGGCAATTCCCGACCGAACCAAACGGTTTCCATGGATCTCAA
TAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCA
GTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACT
GTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCT
CATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACA
GTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGT
TACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCT
GTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATC
ATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGA
ACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAA
AATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACAC
CCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAA
TCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATAC
CTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACA
TGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTT
ACAAAAACTATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTT

>40050_40050_5_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000325324_TNFAIP8_chr5_118728511_ENST00000504642_length(amino acids)=472AA_BP=285
MAAWGEGPTDATSCWEVGAGGPGNSRPNQTVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINV
RWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQDDLRQHRAL
LTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGF
LHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILY
RNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFG

--------------------------------------------------------------
>40050_40050_6_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000325324_TNFAIP8_chr5_118728511_ENST00000513374_length(transcript)=1854nt_BP=926nt
TTTGGAGCTGCGACGCCAAACATGGCGTGTTCCTAGAAGCCGCTTTCGGCATCAGTAGGCGGCGGCGTGGGGTCTGGCAGCGTGGGGAGA
GGGACCAACCGACGCCACTTCGTGTTGGGAAGTGGGAGCGGGAGGGCCGGGCAATTCCCGACCGAACCAAACGGTTTCCATGGATCTCAA
TAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCA
GTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACT
GTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCT
CATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACA
GTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGT
TACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCT
GTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATC
ATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGA
ACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAA
AATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACAC
CCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAA
TCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATAC
CTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACA
TGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTT
ACAAAAACTATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTT
GAAGATGGAGCACTGCTGATTTATGAAGGAAAAAAGAAGAATTTTCTAAAGATTACACATATTTCAGAAAGACTTTACCCAATTCAGTTG
TCAGACATAATGATTTATTTGAAGGCTTGTTTTATTTGAAGAAAAGCATATTGCCAAAAATTCTGGTTAAAAGCTTCCTAACGGGTAACA
GACCATGGGAGAGATATGTGGTTGGGTAATGCAAATGTAGTTATACAAAGAAAAATACAGATGTCTCCAGACCTGAGGACTTTTTAATAG

>40050_40050_6_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000325324_TNFAIP8_chr5_118728511_ENST00000513374_length(amino acids)=472AA_BP=285
MAAWGEGPTDATSCWEVGAGGPGNSRPNQTVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINV
RWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQDDLRQHRAL
LTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGF
LHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILY
RNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFG

--------------------------------------------------------------
>40050_40050_7_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000409296_TNFAIP8_chr5_118728510_ENST00000503646_length(transcript)=2790nt_BP=1007nt
ATAGCACCAGGTGTGAAACTGCTGGGTCATAGAAGATACAGTCACGAGTTGCTTAAGGCTGGGATACATCCTGAGAAATGGGTCGTTAGG
CAATTTTGTTGTTCTATGAACATCATATGAACAAACCTAGATGGTACAGCCTATTATACACTTGGGCTATGTGGTATATAGCTTATTGTA
TCTAGGCTATAAGCCTGTACAGCATGTTACTGCACTGAATACTGTAAGCAGTTGTCACAAAATGGTTTCCATGGATCTCAATAGTGCCAG
CACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCAGTGGGAGAC
ACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACTGTATTTTAA
ACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCTCATCACCAA
CTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACAGTGGCCTGA
ACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGTTACCAAGAC
ACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCTGTGGAATCA
CCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATCATTGAAAGT
GCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGAACGTCTAAA
ACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTC
CAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAAAACAA
GAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAATCAAGATGA
GCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATACCTTTGACCG
GAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGT
TAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTTACAAAAACT
ATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTTGAAGATGGA
GCACTGCTGATTTATGAAGGAAAAAAGAAGAATTTTCTAAAGATTACACATATTTCAGAAAGACTTTACCCAATTCAGTTGTCAGACATA
ATGATTTATTTGAAGGCTTGTTTTATTTGAAGAAAAGCATATTGCCAAAAATTCTGGTTAAAAGCTTCCTAACGGGTAACAGACCATGGG
AGAGATATGTGGTTGGGTAATGCAAATGTAGTTATACAAAGAAAAATACAGATGTCTCCAGACCTGAGGACTTTTTAATAGGGCAGTTGT
TGTGTTGGTGGCACATTGGATATTTCTAACATGTACAAAGCTATGTATTTTGATTTACTTTCATTTCTTGCTATGTATATGTACTTTTCT
TAAAATGCCAAGAACTTTCTCTTGCTATCATTGCTCCTTTTGAAACAATTCAATTTTCATGTCTACAGCTGACTGTTTTGTTAAGATTGA
GTCATCGACATTCAGGATTTAAGTCTGAGGTAGTCAACCCTCAGGAAAAAAAAAATGGCTTATCTGAAATCAGTACTGTGGAAATGAACT
ATATTAGCTATTATGAATAATGTCCAGTATAAGAATATGCTTCTGGAATTGAGTTCTCCTTTTAAGTACCAATGATACTTAAATTTCTCA
GAAATGTAATGGTGTGTCATTGCCTTGAAATGCTTGCTTAGGGCTTCTTTTATGTTATCTTAAAAAGTGCTGGTGAATTTTCCATTTTTT
ACATCCATTTCACATGTAAGAGACAAAAAAGTCTAGATTGGTCTTGATATTGAGATAATAAAAAGTAAGTAGCATTAAGAAAGGTAACAA
TCTTCATTCTACAGATGAACTCATTGAAACAATTTAGGGGAATGAGGGGCAAAAGGGGAGAAATACTGCTAAAGAACATGAGCATAAAAA
TGCGTGCGTTTCAGTGTTTAAGAAGGCTTGATAAAGAATGTCACTTTTTTATTTAACTGATAAGATTTTTGTTATTTTTTACTTTGATAA
GTAAACCAAAGAATATTTGTATTTCAAGCAGTTTGTGTGGTGTTTCTATATAATTTTCTGTGTATAAATAATAAAGTAGGCATTTGTTTA
TTTTGTAAAAAAGAAATGAAAATCTGCTGGCCAGCTATGTCCTCTAGGAAATGACAGACCCAACCACCAGCAATAAACATTTCCATTGTC

>40050_40050_7_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000409296_TNFAIP8_chr5_118728510_ENST00000503646_length(amino acids)=480AA_BP=293
MVQPIIHLGYVVYSLLYLGYKPVQHVTALNTVSSCHKMVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFT
NHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQD
DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPH
KNMEVMGFLHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKT
VIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFL

--------------------------------------------------------------
>40050_40050_8_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000409296_TNFAIP8_chr5_118728510_ENST00000504642_length(transcript)=1638nt_BP=1007nt
ATAGCACCAGGTGTGAAACTGCTGGGTCATAGAAGATACAGTCACGAGTTGCTTAAGGCTGGGATACATCCTGAGAAATGGGTCGTTAGG
CAATTTTGTTGTTCTATGAACATCATATGAACAAACCTAGATGGTACAGCCTATTATACACTTGGGCTATGTGGTATATAGCTTATTGTA
TCTAGGCTATAAGCCTGTACAGCATGTTACTGCACTGAATACTGTAAGCAGTTGTCACAAAATGGTTTCCATGGATCTCAATAGTGCCAG
CACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCAGTGGGAGAC
ACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACTGTATTTTAA
ACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCTCATCACCAA
CTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACAGTGGCCTGA
ACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGTTACCAAGAC
ACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCTGTGGAATCA
CCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATCATTGAAAGT
GCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGAACGTCTAAA
ACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTC
CAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAAAACAA
GAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAATCAAGATGA
GCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATACCTTTGACCG
GAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGT
TAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTTACAAAAACT
ATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTTGAAGATGGA

>40050_40050_8_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000409296_TNFAIP8_chr5_118728510_ENST00000504642_length(amino acids)=480AA_BP=293
MVQPIIHLGYVVYSLLYLGYKPVQHVTALNTVSSCHKMVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFT
NHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQD
DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPH
KNMEVMGFLHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKT
VIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFL

--------------------------------------------------------------
>40050_40050_9_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000409296_TNFAIP8_chr5_118728510_ENST00000513374_length(transcript)=1935nt_BP=1007nt
ATAGCACCAGGTGTGAAACTGCTGGGTCATAGAAGATACAGTCACGAGTTGCTTAAGGCTGGGATACATCCTGAGAAATGGGTCGTTAGG
CAATTTTGTTGTTCTATGAACATCATATGAACAAACCTAGATGGTACAGCCTATTATACACTTGGGCTATGTGGTATATAGCTTATTGTA
TCTAGGCTATAAGCCTGTACAGCATGTTACTGCACTGAATACTGTAAGCAGTTGTCACAAAATGGTTTCCATGGATCTCAATAGTGCCAG
CACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCAGTGGGAGAC
ACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACTGTATTTTAA
ACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCTCATCACCAA
CTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACAGTGGCCTGA
ACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGTTACCAAGAC
ACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCTGTGGAATCA
CCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATCATTGAAAGT
GCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGAACGTCTAAA
ACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTC
CAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAAAACAA
GAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAATCAAGATGA
GCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATACCTTTGACCG
GAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGT
TAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTTACAAAAACT
ATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTTGAAGATGGA
GCACTGCTGATTTATGAAGGAAAAAAGAAGAATTTTCTAAAGATTACACATATTTCAGAAAGACTTTACCCAATTCAGTTGTCAGACATA
ATGATTTATTTGAAGGCTTGTTTTATTTGAAGAAAAGCATATTGCCAAAAATTCTGGTTAAAAGCTTCCTAACGGGTAACAGACCATGGG
AGAGATATGTGGTTGGGTAATGCAAATGTAGTTATACAAAGAAAAATACAGATGTCTCCAGACCTGAGGACTTTTTAATAGGGCAGTTGT

>40050_40050_9_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000409296_TNFAIP8_chr5_118728510_ENST00000513374_length(amino acids)=480AA_BP=293
MVQPIIHLGYVVYSLLYLGYKPVQHVTALNTVSSCHKMVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFT
NHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQD
DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPH
KNMEVMGFLHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKT
VIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFL

--------------------------------------------------------------
>40050_40050_10_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000409296_TNFAIP8_chr5_118728511_ENST00000503646_length(transcript)=2790nt_BP=1007nt
ATAGCACCAGGTGTGAAACTGCTGGGTCATAGAAGATACAGTCACGAGTTGCTTAAGGCTGGGATACATCCTGAGAAATGGGTCGTTAGG
CAATTTTGTTGTTCTATGAACATCATATGAACAAACCTAGATGGTACAGCCTATTATACACTTGGGCTATGTGGTATATAGCTTATTGTA
TCTAGGCTATAAGCCTGTACAGCATGTTACTGCACTGAATACTGTAAGCAGTTGTCACAAAATGGTTTCCATGGATCTCAATAGTGCCAG
CACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCAGTGGGAGAC
ACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACTGTATTTTAA
ACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCTCATCACCAA
CTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACAGTGGCCTGA
ACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGTTACCAAGAC
ACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCTGTGGAATCA
CCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATCATTGAAAGT
GCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGAACGTCTAAA
ACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTC
CAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAAAACAA
GAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAATCAAGATGA
GCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATACCTTTGACCG
GAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGT
TAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTTACAAAAACT
ATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTTGAAGATGGA
GCACTGCTGATTTATGAAGGAAAAAAGAAGAATTTTCTAAAGATTACACATATTTCAGAAAGACTTTACCCAATTCAGTTGTCAGACATA
ATGATTTATTTGAAGGCTTGTTTTATTTGAAGAAAAGCATATTGCCAAAAATTCTGGTTAAAAGCTTCCTAACGGGTAACAGACCATGGG
AGAGATATGTGGTTGGGTAATGCAAATGTAGTTATACAAAGAAAAATACAGATGTCTCCAGACCTGAGGACTTTTTAATAGGGCAGTTGT
TGTGTTGGTGGCACATTGGATATTTCTAACATGTACAAAGCTATGTATTTTGATTTACTTTCATTTCTTGCTATGTATATGTACTTTTCT
TAAAATGCCAAGAACTTTCTCTTGCTATCATTGCTCCTTTTGAAACAATTCAATTTTCATGTCTACAGCTGACTGTTTTGTTAAGATTGA
GTCATCGACATTCAGGATTTAAGTCTGAGGTAGTCAACCCTCAGGAAAAAAAAAATGGCTTATCTGAAATCAGTACTGTGGAAATGAACT
ATATTAGCTATTATGAATAATGTCCAGTATAAGAATATGCTTCTGGAATTGAGTTCTCCTTTTAAGTACCAATGATACTTAAATTTCTCA
GAAATGTAATGGTGTGTCATTGCCTTGAAATGCTTGCTTAGGGCTTCTTTTATGTTATCTTAAAAAGTGCTGGTGAATTTTCCATTTTTT
ACATCCATTTCACATGTAAGAGACAAAAAAGTCTAGATTGGTCTTGATATTGAGATAATAAAAAGTAAGTAGCATTAAGAAAGGTAACAA
TCTTCATTCTACAGATGAACTCATTGAAACAATTTAGGGGAATGAGGGGCAAAAGGGGAGAAATACTGCTAAAGAACATGAGCATAAAAA
TGCGTGCGTTTCAGTGTTTAAGAAGGCTTGATAAAGAATGTCACTTTTTTATTTAACTGATAAGATTTTTGTTATTTTTTACTTTGATAA
GTAAACCAAAGAATATTTGTATTTCAAGCAGTTTGTGTGGTGTTTCTATATAATTTTCTGTGTATAAATAATAAAGTAGGCATTTGTTTA
TTTTGTAAAAAAGAAATGAAAATCTGCTGGCCAGCTATGTCCTCTAGGAAATGACAGACCCAACCACCAGCAATAAACATTTCCATTGTC

>40050_40050_10_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000409296_TNFAIP8_chr5_118728511_ENST00000503646_length(amino acids)=480AA_BP=293
MVQPIIHLGYVVYSLLYLGYKPVQHVTALNTVSSCHKMVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFT
NHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQD
DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPH
KNMEVMGFLHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKT
VIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFL

--------------------------------------------------------------
>40050_40050_11_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000409296_TNFAIP8_chr5_118728511_ENST00000504642_length(transcript)=1638nt_BP=1007nt
ATAGCACCAGGTGTGAAACTGCTGGGTCATAGAAGATACAGTCACGAGTTGCTTAAGGCTGGGATACATCCTGAGAAATGGGTCGTTAGG
CAATTTTGTTGTTCTATGAACATCATATGAACAAACCTAGATGGTACAGCCTATTATACACTTGGGCTATGTGGTATATAGCTTATTGTA
TCTAGGCTATAAGCCTGTACAGCATGTTACTGCACTGAATACTGTAAGCAGTTGTCACAAAATGGTTTCCATGGATCTCAATAGTGCCAG
CACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCAGTGGGAGAC
ACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACTGTATTTTAA
ACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCTCATCACCAA
CTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACAGTGGCCTGA
ACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGTTACCAAGAC
ACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCTGTGGAATCA
CCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATCATTGAAAGT
GCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGAACGTCTAAA
ACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTC
CAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAAAACAA
GAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAATCAAGATGA
GCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATACCTTTGACCG
GAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGT
TAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTTACAAAAACT
ATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTTGAAGATGGA

>40050_40050_11_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000409296_TNFAIP8_chr5_118728511_ENST00000504642_length(amino acids)=480AA_BP=293
MVQPIIHLGYVVYSLLYLGYKPVQHVTALNTVSSCHKMVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFT
NHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQD
DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPH
KNMEVMGFLHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKT
VIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFL

--------------------------------------------------------------
>40050_40050_12_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000409296_TNFAIP8_chr5_118728511_ENST00000513374_length(transcript)=1935nt_BP=1007nt
ATAGCACCAGGTGTGAAACTGCTGGGTCATAGAAGATACAGTCACGAGTTGCTTAAGGCTGGGATACATCCTGAGAAATGGGTCGTTAGG
CAATTTTGTTGTTCTATGAACATCATATGAACAAACCTAGATGGTACAGCCTATTATACACTTGGGCTATGTGGTATATAGCTTATTGTA
TCTAGGCTATAAGCCTGTACAGCATGTTACTGCACTGAATACTGTAAGCAGTTGTCACAAAATGGTTTCCATGGATCTCAATAGTGCCAG
CACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCAGTGGGAGAC
ACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACTGTATTTTAA
ACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCTCATCACCAA
CTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACAGTGGCCTGA
ACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGTTACCAAGAC
ACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCTGTGGAATCA
CCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATCATTGAAAGT
GCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGAACGTCTAAA
ACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTC
CAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAAAACAA
GAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAATCAAGATGA
GCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATACCTTTGACCG
GAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGT
TAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTTACAAAAACT
ATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTTGAAGATGGA
GCACTGCTGATTTATGAAGGAAAAAAGAAGAATTTTCTAAAGATTACACATATTTCAGAAAGACTTTACCCAATTCAGTTGTCAGACATA
ATGATTTATTTGAAGGCTTGTTTTATTTGAAGAAAAGCATATTGCCAAAAATTCTGGTTAAAAGCTTCCTAACGGGTAACAGACCATGGG
AGAGATATGTGGTTGGGTAATGCAAATGTAGTTATACAAAGAAAAATACAGATGTCTCCAGACCTGAGGACTTTTTAATAGGGCAGTTGT

>40050_40050_12_IPO11-TNFAIP8_IPO11_chr5_61770291_ENST00000409296_TNFAIP8_chr5_118728511_ENST00000513374_length(amino acids)=480AA_BP=293
MVQPIIHLGYVVYSLLYLGYKPVQHVTALNTVSSCHKMVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFT
NHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQD
DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPH
KNMEVMGFLHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKT
VIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFL

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Fusion Gene PPI Analysis for IPO11-TNFAIP8


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for IPO11-TNFAIP8


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for IPO11-TNFAIP8


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource