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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ITGA6-RAPGEF4 (FusionGDB2 ID:40446)

Fusion Gene Summary for ITGA6-RAPGEF4

Fusion gene summary

Fusion gene information	Fusion gene name: ITGA6-RAPGEF4
	Fusion gene ID: 40446
		Hgene	Tgene
	Gene symbol	ITGA6	RAPGEF4
	Gene ID	3655	11069
	Gene name	integrin subunit alpha 6	Rap guanine nucleotide exchange factor 4
	Synonyms	CD49f\|ITGA6B\|VLA-6	CAMP-GEFII\|CGEF2\|EPAC\|EPAC 2\|EPAC2\|Nbla00496
	Cytomap	2q31.1	2q31.1
	Type of gene	protein-coding	protein-coding
	Description	integrin alpha-6CD49 antigen-like family member Fintegrin alpha6Bintegrin, alpha 6	rap guanine nucleotide exchange factor 4RAP guanine-nucleotide-exchange factor (GEF) 4Rap guanine nucleotide exchange factor (GEF) 4cAMP-regulated guanine nucleotide exchange factor IIexchange factor directly activated by cAMP 2exchange protein direc
	Modification date	20200329	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000264106, ENST00000264107, ENST00000343713, ENST00000375221, ENST00000409080, ENST00000409532,	ENST00000397087, ENST00000409036, ENST00000473043, ENST00000535187, ENST00000538974, ENST00000539331, ENST00000540783, ENST00000264111, ENST00000397081,
Fusion gene scores	* DoF score	10 X 8 X 6=480	17 X 18 X 9=2754
	# samples	12	19
	** MAII score	log2(12/480*10)=-2 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(19/2754*10)=-3.85745723580402 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: ITGA6 [Title/Abstract] AND RAPGEF4 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ITGA6(173356251)-RAPGEF4(173898642), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across ITGA6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across RAPGEF4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-D7-A4YY-01A	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
ChimerDB4	STAD	TCGA-D7-A4YY	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+

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Fusion Gene ORF analysis for ITGA6-RAPGEF4

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000264106	ENST00000397087	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264106	ENST00000397087	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000264106	ENST00000409036	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264106	ENST00000409036	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000264106	ENST00000473043	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264106	ENST00000473043	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000264106	ENST00000535187	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264106	ENST00000535187	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000264106	ENST00000538974	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264106	ENST00000538974	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000264106	ENST00000539331	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264106	ENST00000539331	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000264106	ENST00000540783	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264106	ENST00000540783	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000264107	ENST00000397087	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264107	ENST00000397087	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000264107	ENST00000409036	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264107	ENST00000409036	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000264107	ENST00000473043	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264107	ENST00000473043	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000264107	ENST00000535187	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264107	ENST00000535187	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000264107	ENST00000538974	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264107	ENST00000538974	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000264107	ENST00000539331	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264107	ENST00000539331	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000264107	ENST00000540783	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000264107	ENST00000540783	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000343713	ENST00000397087	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000343713	ENST00000397087	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000343713	ENST00000409036	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000343713	ENST00000409036	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000343713	ENST00000473043	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000343713	ENST00000473043	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000343713	ENST00000535187	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000343713	ENST00000535187	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000343713	ENST00000538974	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000343713	ENST00000538974	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000343713	ENST00000539331	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000343713	ENST00000539331	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000343713	ENST00000540783	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000343713	ENST00000540783	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000375221	ENST00000397087	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000375221	ENST00000397087	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000375221	ENST00000409036	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000375221	ENST00000409036	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000375221	ENST00000473043	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000375221	ENST00000473043	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000375221	ENST00000535187	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000375221	ENST00000535187	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000375221	ENST00000538974	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000375221	ENST00000538974	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000375221	ENST00000539331	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000375221	ENST00000539331	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000375221	ENST00000540783	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000375221	ENST00000540783	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409080	ENST00000397087	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409080	ENST00000397087	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409080	ENST00000409036	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409080	ENST00000409036	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409080	ENST00000473043	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409080	ENST00000473043	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409080	ENST00000535187	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409080	ENST00000535187	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409080	ENST00000538974	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409080	ENST00000538974	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409080	ENST00000539331	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409080	ENST00000539331	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409080	ENST00000540783	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409080	ENST00000540783	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409532	ENST00000397087	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409532	ENST00000397087	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409532	ENST00000409036	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409532	ENST00000409036	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409532	ENST00000473043	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409532	ENST00000473043	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409532	ENST00000535187	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409532	ENST00000535187	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409532	ENST00000538974	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409532	ENST00000538974	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409532	ENST00000539331	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409532	ENST00000539331	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
5CDS-intron	ENST00000409532	ENST00000540783	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
5CDS-intron	ENST00000409532	ENST00000540783	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
In-frame	ENST00000264106	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
In-frame	ENST00000264106	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
In-frame	ENST00000264106	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
In-frame	ENST00000264106	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
In-frame	ENST00000264107	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
In-frame	ENST00000264107	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
In-frame	ENST00000264107	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
In-frame	ENST00000264107	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
In-frame	ENST00000343713	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
In-frame	ENST00000343713	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
In-frame	ENST00000343713	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
In-frame	ENST00000343713	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
In-frame	ENST00000375221	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
In-frame	ENST00000375221	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
In-frame	ENST00000375221	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
In-frame	ENST00000375221	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
In-frame	ENST00000409080	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
In-frame	ENST00000409080	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
In-frame	ENST00000409080	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
In-frame	ENST00000409080	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
In-frame	ENST00000409532	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
In-frame	ENST00000409532	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+
In-frame	ENST00000409532	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+
In-frame	ENST00000409532	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000409532	ITGA6	chr2	173356251	+	ENST00000264111	RAPGEF4	chr2	173898642	+	4349	2844	54	3230	1058
ENST00000409532	ITGA6	chr2	173356251	+	ENST00000397081	RAPGEF4	chr2	173898642	+	4351	2844	54	3230	1058
ENST00000264107	ITGA6	chr2	173356251	+	ENST00000264111	RAPGEF4	chr2	173898642	+	4727	3222	0	3608	1202
ENST00000264107	ITGA6	chr2	173356251	+	ENST00000397081	RAPGEF4	chr2	173898642	+	4729	3222	0	3608	1202
ENST00000343713	ITGA6	chr2	173356251	+	ENST00000264111	RAPGEF4	chr2	173898642	+	4681	3176	167	3562	1131
ENST00000343713	ITGA6	chr2	173356251	+	ENST00000397081	RAPGEF4	chr2	173898642	+	4683	3176	167	3562	1131
ENST00000264106	ITGA6	chr2	173356251	+	ENST00000264111	RAPGEF4	chr2	173898642	+	4813	3308	167	3694	1175
ENST00000264106	ITGA6	chr2	173356251	+	ENST00000397081	RAPGEF4	chr2	173898642	+	4815	3308	167	3694	1175
ENST00000375221	ITGA6	chr2	173356251	+	ENST00000264111	RAPGEF4	chr2	173898642	+	4813	3308	167	3694	1175
ENST00000375221	ITGA6	chr2	173356251	+	ENST00000397081	RAPGEF4	chr2	173898642	+	4815	3308	167	3694	1175
ENST00000409080	ITGA6	chr2	173356251	+	ENST00000264111	RAPGEF4	chr2	173898642	+	4493	2988	0	3374	1124
ENST00000409080	ITGA6	chr2	173356251	+	ENST00000397081	RAPGEF4	chr2	173898642	+	4495	2988	0	3374	1124
ENST00000409532	ITGA6	chr2	173356251	+	ENST00000264111	RAPGEF4	chr2	173898641	+	4349	2844	54	3230	1058
ENST00000409532	ITGA6	chr2	173356251	+	ENST00000397081	RAPGEF4	chr2	173898641	+	4351	2844	54	3230	1058
ENST00000264107	ITGA6	chr2	173356251	+	ENST00000264111	RAPGEF4	chr2	173898641	+	4727	3222	0	3608	1202
ENST00000264107	ITGA6	chr2	173356251	+	ENST00000397081	RAPGEF4	chr2	173898641	+	4729	3222	0	3608	1202
ENST00000343713	ITGA6	chr2	173356251	+	ENST00000264111	RAPGEF4	chr2	173898641	+	4681	3176	167	3562	1131
ENST00000343713	ITGA6	chr2	173356251	+	ENST00000397081	RAPGEF4	chr2	173898641	+	4683	3176	167	3562	1131
ENST00000264106	ITGA6	chr2	173356251	+	ENST00000264111	RAPGEF4	chr2	173898641	+	4813	3308	167	3694	1175
ENST00000264106	ITGA6	chr2	173356251	+	ENST00000397081	RAPGEF4	chr2	173898641	+	4815	3308	167	3694	1175
ENST00000375221	ITGA6	chr2	173356251	+	ENST00000264111	RAPGEF4	chr2	173898641	+	4813	3308	167	3694	1175
ENST00000375221	ITGA6	chr2	173356251	+	ENST00000397081	RAPGEF4	chr2	173898641	+	4815	3308	167	3694	1175
ENST00000409080	ITGA6	chr2	173356251	+	ENST00000264111	RAPGEF4	chr2	173898641	+	4493	2988	0	3374	1124
ENST00000409080	ITGA6	chr2	173356251	+	ENST00000397081	RAPGEF4	chr2	173898641	+	4495	2988	0	3374	1124

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000409532	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+	0.000147073	0.9998529
ENST00000409532	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+	0.000147481	0.99985254
ENST00000264107	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+	0.000421796	0.9995782
ENST00000264107	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+	0.000424554	0.99957544
ENST00000343713	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+	0.000188305	0.9998117
ENST00000343713	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+	0.000189482	0.9998105
ENST00000264106	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+	0.000187319	0.99981266
ENST00000264106	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+	0.000188168	0.9998118
ENST00000375221	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+	0.000187319	0.99981266
ENST00000375221	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+	0.000188168	0.9998118
ENST00000409080	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+	0.000281991	0.999718
ENST00000409080	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898642	+	0.000283208	0.9997168
ENST00000409532	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000147073	0.9998529
ENST00000409532	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000147481	0.99985254
ENST00000264107	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000421796	0.9995782
ENST00000264107	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000424554	0.99957544
ENST00000343713	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000188305	0.9998117
ENST00000343713	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000189482	0.9998105
ENST00000264106	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000187319	0.99981266
ENST00000264106	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000188168	0.9998118
ENST00000375221	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000187319	0.99981266
ENST00000375221	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000188168	0.9998118
ENST00000409080	ENST00000264111	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000281991	0.999718
ENST00000409080	ENST00000397081	ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000283208	0.9997168

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Fusion Genomic Features for ITGA6-RAPGEF4

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000197227	0.99980277
ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000197227	0.99980277
ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000197227	0.99980277
ITGA6	chr2	173356251	+	RAPGEF4	chr2	173898641	+	0.000197227	0.99980277

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ITGA6-RAPGEF4

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:173356251/chr2:173898642)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

363_371

1035

1131.0

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

425_433

1035

1131.0

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

480_488

1035

1131.0

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

363_371

996

1648.6666666666667

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

425_433

996

1648.6666666666667

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

480_488

996

1648.6666666666667

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

363_371

991

1728.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

425_433

991

1728.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

480_488

991

1728.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

363_371

1035

1772.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

425_433

1035

1772.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

480_488

1035

1772.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

363_371

996

1092.0

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

425_433

996

1092.0

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

480_488

996

1092.0

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

363_371

877

1085.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

425_433

877

1085.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

480_488

877

1085.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

363_371

1035

1131.0

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

425_433

1035

1131.0

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

480_488

1035

1131.0

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

363_371

996

1648.6666666666667

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

425_433

996

1648.6666666666667

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

480_488

996

1648.6666666666667

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

363_371

991

1728.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

425_433

991

1728.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

480_488

991

1728.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

363_371

1035

1772.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

425_433

1035

1772.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

480_488

1035

1772.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

363_371

996

1092.0

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

425_433

996

1092.0

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

480_488

996

1092.0

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

363_371

877

1085.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

425_433

877

1085.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

480_488

877

1085.3333333333333

Calcium binding

Ontology_term=ECO:0000255

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

101_166

1035

1131.0

Repeat

FG-GAP 2

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

176_229

1035

1131.0

Repeat

FG-GAP 3

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

283_339

1035

1131.0

Repeat

FG-GAP 4

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

30_95

1035

1131.0

Repeat

FG-GAP 1

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

340_402

1035

1131.0

Repeat

FG-GAP 5

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

403_458

1035

1131.0

Repeat

FG-GAP 6

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

459_518

1035

1131.0

Repeat

FG-GAP 7

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

101_166

996

1648.6666666666667

Repeat

FG-GAP 2

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

176_229

996

1648.6666666666667

Repeat

FG-GAP 3

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

283_339

996

1648.6666666666667

Repeat

FG-GAP 4

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

30_95

996

1648.6666666666667

Repeat

FG-GAP 1

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

340_402

996

1648.6666666666667

Repeat

FG-GAP 5

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

403_458

996

1648.6666666666667

Repeat

FG-GAP 6

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

459_518

996

1648.6666666666667

Repeat

FG-GAP 7

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

101_166

991

1728.3333333333333

Repeat

FG-GAP 2

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

176_229

991

1728.3333333333333

Repeat

FG-GAP 3

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

283_339

991

1728.3333333333333

Repeat

FG-GAP 4

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

30_95

991

1728.3333333333333

Repeat

FG-GAP 1

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

340_402

991

1728.3333333333333

Repeat

FG-GAP 5

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

403_458

991

1728.3333333333333

Repeat

FG-GAP 6

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

459_518

991

1728.3333333333333

Repeat

FG-GAP 7

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

101_166

1035

1772.3333333333333

Repeat

FG-GAP 2

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

176_229

1035

1772.3333333333333

Repeat

FG-GAP 3

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

283_339

1035

1772.3333333333333

Repeat

FG-GAP 4

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

30_95

1035

1772.3333333333333

Repeat

FG-GAP 1

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

340_402

1035

1772.3333333333333

Repeat

FG-GAP 5

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

403_458

1035

1772.3333333333333

Repeat

FG-GAP 6

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

459_518

1035

1772.3333333333333

Repeat

FG-GAP 7

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

101_166

996

1092.0

Repeat

FG-GAP 2

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

176_229

996

1092.0

Repeat

FG-GAP 3

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

283_339

996

1092.0

Repeat

FG-GAP 4

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

30_95

996

1092.0

Repeat

FG-GAP 1

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

340_402

996

1092.0

Repeat

FG-GAP 5

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

403_458

996

1092.0

Repeat

FG-GAP 6

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

459_518

996

1092.0

Repeat

FG-GAP 7

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

101_166

877

1085.3333333333333

Repeat

FG-GAP 2

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

176_229

877

1085.3333333333333

Repeat

FG-GAP 3

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

283_339

877

1085.3333333333333

Repeat

FG-GAP 4

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

30_95

877

1085.3333333333333

Repeat

FG-GAP 1

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

340_402

877

1085.3333333333333

Repeat

FG-GAP 5

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

403_458

877

1085.3333333333333

Repeat

FG-GAP 6

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

459_518

877

1085.3333333333333

Repeat

FG-GAP 7

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

101_166

1035

1131.0

Repeat

FG-GAP 2

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

176_229

1035

1131.0

Repeat

FG-GAP 3

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

283_339

1035

1131.0

Repeat

FG-GAP 4

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

30_95

1035

1131.0

Repeat

FG-GAP 1

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

340_402

1035

1131.0

Repeat

FG-GAP 5

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

403_458

1035

1131.0

Repeat

FG-GAP 6

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

459_518

1035

1131.0

Repeat

FG-GAP 7

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

101_166

996

1648.6666666666667

Repeat

FG-GAP 2

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

176_229

996

1648.6666666666667

Repeat

FG-GAP 3

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

283_339

996

1648.6666666666667

Repeat

FG-GAP 4

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

30_95

996

1648.6666666666667

Repeat

FG-GAP 1

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

340_402

996

1648.6666666666667

Repeat

FG-GAP 5

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

403_458

996

1648.6666666666667

Repeat

FG-GAP 6

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

459_518

996

1648.6666666666667

Repeat

FG-GAP 7

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

101_166

991

1728.3333333333333

Repeat

FG-GAP 2

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

176_229

991

1728.3333333333333

Repeat

FG-GAP 3

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

283_339

991

1728.3333333333333

Repeat

FG-GAP 4

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

30_95

991

1728.3333333333333

Repeat

FG-GAP 1

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

340_402

991

1728.3333333333333

Repeat

FG-GAP 5

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

403_458

991

1728.3333333333333

Repeat

FG-GAP 6

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

459_518

991

1728.3333333333333

Repeat

FG-GAP 7

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

101_166

1035

1772.3333333333333

Repeat

FG-GAP 2

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

176_229

1035

1772.3333333333333

Repeat

FG-GAP 3

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

283_339

1035

1772.3333333333333

Repeat

FG-GAP 4

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

30_95

1035

1772.3333333333333

Repeat

FG-GAP 1

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

340_402

1035

1772.3333333333333

Repeat

FG-GAP 5

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

403_458

1035

1772.3333333333333

Repeat

FG-GAP 6

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

459_518

1035

1772.3333333333333

Repeat

FG-GAP 7

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

101_166

996

1092.0

Repeat

FG-GAP 2

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

176_229

996

1092.0

Repeat

FG-GAP 3

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

283_339

996

1092.0

Repeat

FG-GAP 4

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

30_95

996

1092.0

Repeat

FG-GAP 1

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

340_402

996

1092.0

Repeat

FG-GAP 5

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

403_458

996

1092.0

Repeat

FG-GAP 6

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

459_518

996

1092.0

Repeat

FG-GAP 7

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

101_166

877

1085.3333333333333

Repeat

FG-GAP 2

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

176_229

877

1085.3333333333333

Repeat

FG-GAP 3

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

283_339

877

1085.3333333333333

Repeat

FG-GAP 4

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

30_95

877

1085.3333333333333

Repeat

FG-GAP 1

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

340_402

877

1085.3333333333333

Repeat

FG-GAP 5

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

403_458

877

1085.3333333333333

Repeat

FG-GAP 6

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

459_518

877

1085.3333333333333

Repeat

FG-GAP 7

Tgene

RAPGEF4

chr2:173356251

chr2:173898641

ENST00000397087

772_1009

739

868.0

Domain

Ras-GEF

Tgene

RAPGEF4

chr2:173356251

chr2:173898642

ENST00000397087

772_1009

739

868.0

Domain

Ras-GEF

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

1079_1083

1035

1131.0

Motif

Note=GFFKR motif

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

1079_1083

996

1648.6666666666667

Motif

Note=GFFKR motif

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

1079_1083

991

1728.3333333333333

Motif

Note=GFFKR motif

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

1079_1083

1035

1772.3333333333333

Motif

Note=GFFKR motif

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

1079_1083

996

1092.0

Motif

Note=GFFKR motif

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

1079_1083

877

1085.3333333333333

Motif

Note=GFFKR motif

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

1079_1083

1035

1131.0

Motif

Note=GFFKR motif

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

1079_1083

996

1648.6666666666667

Motif

Note=GFFKR motif

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

1079_1083

991

1728.3333333333333

Motif

Note=GFFKR motif

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

1079_1083

1035

1772.3333333333333

Motif

Note=GFFKR motif

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

1079_1083

996

1092.0

Motif

Note=GFFKR motif

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

1079_1083

877

1085.3333333333333

Motif

Note=GFFKR motif

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

1077_1130

1035

1131.0

Topological domain

Cytoplasmic

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

24_1050

1035

1131.0

Topological domain

Extracellular

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

1077_1130

996

1648.6666666666667

Topological domain

Cytoplasmic

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

24_1050

996

1648.6666666666667

Topological domain

Extracellular

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

1077_1130

991

1728.3333333333333

Topological domain

Cytoplasmic

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

24_1050

991

1728.3333333333333

Topological domain

Extracellular

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

1077_1130

1035

1772.3333333333333

Topological domain

Cytoplasmic

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

24_1050

1035

1772.3333333333333

Topological domain

Extracellular

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

1077_1130

996

1092.0

Topological domain

Cytoplasmic

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

24_1050

996

1092.0

Topological domain

Extracellular

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

1077_1130

877

1085.3333333333333

Topological domain

Cytoplasmic

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

24_1050

877

1085.3333333333333

Topological domain

Extracellular

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

1077_1130

1035

1131.0

Topological domain

Cytoplasmic

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

24_1050

1035

1131.0

Topological domain

Extracellular

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

1077_1130

996

1648.6666666666667

Topological domain

Cytoplasmic

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

24_1050

996

1648.6666666666667

Topological domain

Extracellular

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

1077_1130

991

1728.3333333333333

Topological domain

Cytoplasmic

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

24_1050

991

1728.3333333333333

Topological domain

Extracellular

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

1077_1130

1035

1772.3333333333333

Topological domain

Cytoplasmic

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

24_1050

1035

1772.3333333333333

Topological domain

Extracellular

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

1077_1130

996

1092.0

Topological domain

Cytoplasmic

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

24_1050

996

1092.0

Topological domain

Extracellular

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

1077_1130

877

1085.3333333333333

Topological domain

Cytoplasmic

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

24_1050

877

1085.3333333333333

Topological domain

Extracellular

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264106

1051_1076

1035

1131.0

Transmembrane

Helical

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000264107

1051_1076

996

1648.6666666666667

Transmembrane

Helical

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000343713

1051_1076

991

1728.3333333333333

Transmembrane

Helical

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000375221

1051_1076

1035

1772.3333333333333

Transmembrane

Helical

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409080

1051_1076

996

1092.0

Transmembrane

Helical

Hgene

ITGA6

chr2:173356251

chr2:173898641

ENST00000409532

1051_1076

877

1085.3333333333333

Transmembrane

Helical

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264106

1051_1076

1035

1131.0

Transmembrane

Helical

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000264107

1051_1076

996

1648.6666666666667

Transmembrane

Helical

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000343713

1051_1076

991

1728.3333333333333

Transmembrane

Helical

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000375221

1051_1076

1035

1772.3333333333333

Transmembrane

Helical

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409080

1051_1076

996

1092.0

Transmembrane

Helical

Hgene

ITGA6

chr2:173356251

chr2:173898642

ENST00000409532

1051_1076

877

1085.3333333333333

Transmembrane

Helical

Tgene

RAPGEF4

chr2:173356251

chr2:173898641

ENST00000397081

216_291

883

1012.0

Domain

DEP

Tgene

RAPGEF4

chr2:173356251

chr2:173898641

ENST00000397081

496_634

883

1012.0

Domain

N-terminal Ras-GEF

Tgene

RAPGEF4

chr2:173356251

chr2:173898641

ENST00000397081

772_1009

883

1012.0

Domain

Ras-GEF

Tgene

RAPGEF4

chr2:173356251

chr2:173898641

ENST00000397087

216_291

739

868.0

Domain

DEP

Tgene

RAPGEF4

chr2:173356251

chr2:173898641

ENST00000397087

496_634

739

868.0

Domain

N-terminal Ras-GEF

Tgene

RAPGEF4

chr2:173356251

chr2:173898642

ENST00000397081

216_291

883

1012.0

Domain

DEP

Tgene

RAPGEF4

chr2:173356251

chr2:173898642

ENST00000397081

496_634

883

1012.0

Domain

N-terminal Ras-GEF

Tgene

RAPGEF4

chr2:173356251

chr2:173898642

ENST00000397081

772_1009

883

1012.0

Domain

Ras-GEF

Tgene

RAPGEF4

chr2:173356251

chr2:173898642

ENST00000397087

216_291

739

868.0

Domain

DEP

Tgene

RAPGEF4

chr2:173356251

chr2:173898642

ENST00000397087

496_634

739

868.0

Domain

N-terminal Ras-GEF

Tgene

RAPGEF4

chr2:173356251

chr2:173898641

ENST00000397081

356_476

883

1012.0

Nucleotide binding

Note=cAMP 2

Tgene

RAPGEF4

chr2:173356251

chr2:173898641

ENST00000397081

43_166

883

1012.0

Nucleotide binding

Note=cAMP 1

Tgene

RAPGEF4

chr2:173356251

chr2:173898641

ENST00000397087

356_476

739

868.0

Nucleotide binding

Note=cAMP 2

Tgene

RAPGEF4

chr2:173356251

chr2:173898641

ENST00000397087

43_166

739

868.0

Nucleotide binding

Note=cAMP 1

Tgene

RAPGEF4

chr2:173356251

chr2:173898642

ENST00000397081

356_476

883

1012.0

Nucleotide binding

Note=cAMP 2

Tgene

RAPGEF4

chr2:173356251

chr2:173898642

ENST00000397081

43_166

883

1012.0

Nucleotide binding

Note=cAMP 1

Tgene

RAPGEF4

chr2:173356251

chr2:173898642

ENST00000397087

356_476

739

868.0

Nucleotide binding

Note=cAMP 2

Tgene

RAPGEF4

chr2:173356251

chr2:173898642

ENST00000397087

43_166

739

868.0

Nucleotide binding

Note=cAMP 1

Top

Fusion Gene Sequence for ITGA6-RAPGEF4

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>40446_40446_1_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264106_RAPGEF4_chr2_173898641_ENST00000264111_length(transcript)=4813nt_BP=3308nt
AACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCGCGACCCGTCCCGGGGGTGGGGCCGGGCGCAG
CGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCCCGGAGCGCAGGGCGGCCGCTGCAGGTCCCCG
CTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAG
CCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGC
AACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGC
TGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATC
AGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATA
CGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGA
GCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACA
TTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAGAATAACACTTTTTTTGACATGAACATCTTTG
AAGATGGGCCTTATGAAGTTGGTGGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTTCCTGCTAACAGTTACTTAGGCCTGCTGTTTT
TGACCAGCGTTTCCTATACAGATCCTGATCAGTTTGTTTATAAAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGA
TGAATAGCTACCTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCA
ATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCT
CTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAG
ATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAG
ATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACT
TGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGAT
ATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGAT
CCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTG
GGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAG
CTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTC
TGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTG
CCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGA
CAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCA
CCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTT
TAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGT
TTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGC
AAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACA
CCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTG
AACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAG
ATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTC
AGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCAC
AAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAA
AATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGC
TGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTC
TCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGA
AGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCA
TCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAA
TGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATC
AGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGAC
CATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCC
ACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAAT
TATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTT
GCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGA
GTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAA
GGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACAT
TATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAAT
GTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTA
GAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGC
TACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTC
AAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTA
TTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATC

>40446_40446_1_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264106_RAPGEF4_chr2_173898641_ENST00000264111_length(amino acids)=1175AA_BP=1
MQVPAPLPVRPPMAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN
RTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMD
GGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYL
GLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDG
EGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGA
PYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTAC
GAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRP
IPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQ
KDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTE
VTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTA
TLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC
PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKL
EPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRL

--------------------------------------------------------------
>40446_40446_2_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264106_RAPGEF4_chr2_173898641_ENST00000397081_length(transcript)=4815nt_BP=3308nt
AACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCGCGACCCGTCCCGGGGGTGGGGCCGGGCGCAG
CGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCCCGGAGCGCAGGGCGGCCGCTGCAGGTCCCCG
CTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAG
CCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGC
AACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGC
TGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATC
AGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATA
CGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGA
GCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACA
TTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAGAATAACACTTTTTTTGACATGAACATCTTTG
AAGATGGGCCTTATGAAGTTGGTGGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTTCCTGCTAACAGTTACTTAGGCCTGCTGTTTT
TGACCAGCGTTTCCTATACAGATCCTGATCAGTTTGTTTATAAAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGA
TGAATAGCTACCTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCA
ATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCT
CTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAG
ATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAG
ATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACT
TGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGAT
ATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGAT
CCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTG
GGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAG
CTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTC
TGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTG
CCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGA
CAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCA
CCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTT
TAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGT
TTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGC
AAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACA
CCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTG
AACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAG
ATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTC
AGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCAC
AAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAA
AATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGC
TGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTC
TCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGA
AGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCA
TCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAA
TGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATC
AGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGAC
CATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCC
ACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAAT
TATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTT
GCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGA
GTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAA
GGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACAT
TATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAAT
GTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTA
GAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGC
TACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTC
AAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTA
TTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATC

>40446_40446_2_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264106_RAPGEF4_chr2_173898641_ENST00000397081_length(amino acids)=1175AA_BP=1
MQVPAPLPVRPPMAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN
RTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMD
GGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYL
GLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDG
EGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGA
PYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTAC
GAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRP
IPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQ
KDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTE
VTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTA
TLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC
PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKL
EPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRL

--------------------------------------------------------------
>40446_40446_3_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264106_RAPGEF4_chr2_173898642_ENST00000264111_length(transcript)=4813nt_BP=3308nt
AACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCGCGACCCGTCCCGGGGGTGGGGCCGGGCGCAG
CGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCCCGGAGCGCAGGGCGGCCGCTGCAGGTCCCCG
CTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAG
CCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGC
AACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGC
TGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATC
AGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATA
CGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGA
GCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACA
TTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAGAATAACACTTTTTTTGACATGAACATCTTTG
AAGATGGGCCTTATGAAGTTGGTGGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTTCCTGCTAACAGTTACTTAGGCCTGCTGTTTT
TGACCAGCGTTTCCTATACAGATCCTGATCAGTTTGTTTATAAAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGA
TGAATAGCTACCTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCA
ATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCT
CTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAG
ATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAG
ATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACT
TGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGAT
ATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGAT
CCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTG
GGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAG
CTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTC
TGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTG
CCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGA
CAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCA
CCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTT
TAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGT
TTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGC
AAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACA
CCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTG
AACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAG
ATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTC
AGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCAC
AAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAA
AATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGC
TGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTC
TCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGA
AGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCA
TCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAA
TGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATC
AGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGAC
CATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCC
ACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAAT
TATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTT
GCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGA
GTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAA
GGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACAT
TATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAAT
GTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTA
GAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGC
TACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTC
AAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTA
TTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATC

>40446_40446_3_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264106_RAPGEF4_chr2_173898642_ENST00000264111_length(amino acids)=1175AA_BP=1
MQVPAPLPVRPPMAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN
RTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMD
GGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYL
GLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDG
EGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGA
PYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTAC
GAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRP
IPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQ
KDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTE
VTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTA
TLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC
PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKL
EPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRL

--------------------------------------------------------------
>40446_40446_4_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264106_RAPGEF4_chr2_173898642_ENST00000397081_length(transcript)=4815nt_BP=3308nt
AACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCGCGACCCGTCCCGGGGGTGGGGCCGGGCGCAG
CGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCCCGGAGCGCAGGGCGGCCGCTGCAGGTCCCCG
CTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAG
CCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGC
AACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGC
TGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATC
AGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATA
CGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGA
GCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACA
TTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAGAATAACACTTTTTTTGACATGAACATCTTTG
AAGATGGGCCTTATGAAGTTGGTGGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTTCCTGCTAACAGTTACTTAGGCCTGCTGTTTT
TGACCAGCGTTTCCTATACAGATCCTGATCAGTTTGTTTATAAAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGA
TGAATAGCTACCTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCA
ATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCT
CTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAG
ATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAG
ATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACT
TGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGAT
ATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGAT
CCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTG
GGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAG
CTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTC
TGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTG
CCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGA
CAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCA
CCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTT
TAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGT
TTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGC
AAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACA
CCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTG
AACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAG
ATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTC
AGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCAC
AAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAA
AATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGC
TGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTC
TCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGA
AGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCA
TCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAA
TGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATC
AGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGAC
CATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCC
ACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAAT
TATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTT
GCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGA
GTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAA
GGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACAT
TATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAAT
GTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTA
GAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGC
TACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTC
AAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTA
TTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATC

>40446_40446_4_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264106_RAPGEF4_chr2_173898642_ENST00000397081_length(amino acids)=1175AA_BP=1
MQVPAPLPVRPPMAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN
RTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMD
GGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYL
GLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDG
EGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGA
PYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTAC
GAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRP
IPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQ
KDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTE
VTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTA
TLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC
PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKL
EPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRL

--------------------------------------------------------------
>40446_40446_5_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264107_RAPGEF4_chr2_173898641_ENST00000264111_length(transcript)=4727nt_BP=3222nt
TTGATAAAACGCCTGCGAGTCTCCAGAGAACAACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCG
CGACCCGTCCCGGGGGTGGGGCCGGGCGCAGCGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCC
CGGAGCGCAGGGCGGCCGCTGCAGGTCCCCGCTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTG
TCGGCGGGGCTCCTGTCCCGGCTCGGCGCAGCCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGC
CTCTTCGGCTTCTCGCTGGCCATGCACTGGCAACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTT
CCACTGCAGAGAGCCAACAGAACGGGAGGGCTGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGAT
GCTGACCCCACGTCAGAAAGCAAGGAAGATCAGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCT
CACCGATATGAAAAAAGGCAGCATGTTAATACGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGG
ATTGAAGACGATATGGATGGGGGAGATTGGAGCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTA
GCAGCTACTTTTACTAAAGACTTTCATTACATTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAG
AATAACACTTTTTTTGACATGAACATCTTTGAAGATGGGCCTTATGAAGTTGGTGGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTT
CCTGCTAACAGTTACTTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGA
GCCAATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTG
GCCTCTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGAT
AGAGATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACC
AAAGATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGAT
GACTTGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTT
GGATATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTC
AGATCCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCT
AGTGGGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTT
GAAGCTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTA
ACTCTGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATA
ACTGCCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCC
AAGACAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTT
TGCACCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATT
GCTTTAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCA
ACGTTTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGC
TCGCAAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTT
GACACCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTT
ATTGAACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCT
GAAGATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAAC
ATTCAGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAG
CCACAAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAAC
AGAAAATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGG
GGGCTGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGAC
ATTCTCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTC
AAGAAGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCT
CTCATCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAA
AAAATGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAAC
CATCAGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGT
CGACCATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTAT
TGCCACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAG
GAATTATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTT
CTTTGCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCT
AAGAGTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCG
GGAAGGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACC
ACATTATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTA
CAATGTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAA
AGTAGAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTAT
TGGCTACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCAC
TTTCAAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTA
TTTATTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTA

>40446_40446_5_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264107_RAPGEF4_chr2_173898641_ENST00000264111_length(amino acids)=1202AA_BP=0
LIKRLRVSREQRAHSAVASCPRGGAAGRRARPVPGVGPGAAARGGEGGCGSSSAAASDPARSAGRPLQVPAPLPVRPPMAAAGQLCLLYL
SAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDND
ADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQQGV
AATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPR
ANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGT
KDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIF
RSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQEL
TLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKF
CTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNG
SQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKS
EDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDN
RKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKF
KKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKN

--------------------------------------------------------------
>40446_40446_6_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264107_RAPGEF4_chr2_173898641_ENST00000397081_length(transcript)=4729nt_BP=3222nt
TTGATAAAACGCCTGCGAGTCTCCAGAGAACAACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCG
CGACCCGTCCCGGGGGTGGGGCCGGGCGCAGCGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCC
CGGAGCGCAGGGCGGCCGCTGCAGGTCCCCGCTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTG
TCGGCGGGGCTCCTGTCCCGGCTCGGCGCAGCCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGC
CTCTTCGGCTTCTCGCTGGCCATGCACTGGCAACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTT
CCACTGCAGAGAGCCAACAGAACGGGAGGGCTGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGAT
GCTGACCCCACGTCAGAAAGCAAGGAAGATCAGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCT
CACCGATATGAAAAAAGGCAGCATGTTAATACGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGG
ATTGAAGACGATATGGATGGGGGAGATTGGAGCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTA
GCAGCTACTTTTACTAAAGACTTTCATTACATTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAG
AATAACACTTTTTTTGACATGAACATCTTTGAAGATGGGCCTTATGAAGTTGGTGGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTT
CCTGCTAACAGTTACTTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGA
GCCAATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTG
GCCTCTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGAT
AGAGATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACC
AAAGATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGAT
GACTTGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTT
GGATATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTC
AGATCCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCT
AGTGGGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTT
GAAGCTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTA
ACTCTGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATA
ACTGCCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCC
AAGACAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTT
TGCACCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATT
GCTTTAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCA
ACGTTTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGC
TCGCAAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTT
GACACCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTT
ATTGAACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCT
GAAGATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAAC
ATTCAGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAG
CCACAAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAAC
AGAAAATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGG
GGGCTGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGAC
ATTCTCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTC
AAGAAGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCT
CTCATCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAA
AAAATGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAAC
CATCAGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGT
CGACCATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTAT
TGCCACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAG
GAATTATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTT
CTTTGCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCT
AAGAGTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCG
GGAAGGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACC
ACATTATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTA
CAATGTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAA
AGTAGAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTAT
TGGCTACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCAC
TTTCAAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTA
TTTATTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTA

>40446_40446_6_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264107_RAPGEF4_chr2_173898641_ENST00000397081_length(amino acids)=1202AA_BP=0
LIKRLRVSREQRAHSAVASCPRGGAAGRRARPVPGVGPGAAARGGEGGCGSSSAAASDPARSAGRPLQVPAPLPVRPPMAAAGQLCLLYL
SAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDND
ADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQQGV
AATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPR
ANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGT
KDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIF
RSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQEL
TLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKF
CTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNG
SQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKS
EDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDN
RKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKF
KKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKN

--------------------------------------------------------------
>40446_40446_7_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264107_RAPGEF4_chr2_173898642_ENST00000264111_length(transcript)=4727nt_BP=3222nt
TTGATAAAACGCCTGCGAGTCTCCAGAGAACAACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCG
CGACCCGTCCCGGGGGTGGGGCCGGGCGCAGCGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCC
CGGAGCGCAGGGCGGCCGCTGCAGGTCCCCGCTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTG
TCGGCGGGGCTCCTGTCCCGGCTCGGCGCAGCCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGC
CTCTTCGGCTTCTCGCTGGCCATGCACTGGCAACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTT
CCACTGCAGAGAGCCAACAGAACGGGAGGGCTGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGAT
GCTGACCCCACGTCAGAAAGCAAGGAAGATCAGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCT
CACCGATATGAAAAAAGGCAGCATGTTAATACGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGG
ATTGAAGACGATATGGATGGGGGAGATTGGAGCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTA
GCAGCTACTTTTACTAAAGACTTTCATTACATTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAG
AATAACACTTTTTTTGACATGAACATCTTTGAAGATGGGCCTTATGAAGTTGGTGGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTT
CCTGCTAACAGTTACTTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGA
GCCAATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTG
GCCTCTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGAT
AGAGATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACC
AAAGATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGAT
GACTTGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTT
GGATATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTC
AGATCCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCT
AGTGGGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTT
GAAGCTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTA
ACTCTGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATA
ACTGCCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCC
AAGACAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTT
TGCACCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATT
GCTTTAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCA
ACGTTTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGC
TCGCAAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTT
GACACCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTT
ATTGAACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCT
GAAGATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAAC
ATTCAGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAG
CCACAAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAAC
AGAAAATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGG
GGGCTGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGAC
ATTCTCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTC
AAGAAGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCT
CTCATCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAA
AAAATGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAAC
CATCAGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGT
CGACCATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTAT
TGCCACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAG
GAATTATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTT
CTTTGCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCT
AAGAGTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCG
GGAAGGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACC
ACATTATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTA
CAATGTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAA
AGTAGAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTAT
TGGCTACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCAC
TTTCAAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTA
TTTATTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTA

>40446_40446_7_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264107_RAPGEF4_chr2_173898642_ENST00000264111_length(amino acids)=1202AA_BP=0
LIKRLRVSREQRAHSAVASCPRGGAAGRRARPVPGVGPGAAARGGEGGCGSSSAAASDPARSAGRPLQVPAPLPVRPPMAAAGQLCLLYL
SAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDND
ADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQQGV
AATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPR
ANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGT
KDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIF
RSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQEL
TLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKF
CTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNG
SQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKS
EDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDN
RKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKF
KKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKN

--------------------------------------------------------------
>40446_40446_8_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264107_RAPGEF4_chr2_173898642_ENST00000397081_length(transcript)=4729nt_BP=3222nt
TTGATAAAACGCCTGCGAGTCTCCAGAGAACAACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCG
CGACCCGTCCCGGGGGTGGGGCCGGGCGCAGCGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCC
CGGAGCGCAGGGCGGCCGCTGCAGGTCCCCGCTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTG
TCGGCGGGGCTCCTGTCCCGGCTCGGCGCAGCCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGC
CTCTTCGGCTTCTCGCTGGCCATGCACTGGCAACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTT
CCACTGCAGAGAGCCAACAGAACGGGAGGGCTGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGAT
GCTGACCCCACGTCAGAAAGCAAGGAAGATCAGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCT
CACCGATATGAAAAAAGGCAGCATGTTAATACGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGG
ATTGAAGACGATATGGATGGGGGAGATTGGAGCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTA
GCAGCTACTTTTACTAAAGACTTTCATTACATTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAG
AATAACACTTTTTTTGACATGAACATCTTTGAAGATGGGCCTTATGAAGTTGGTGGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTT
CCTGCTAACAGTTACTTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGA
GCCAATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTG
GCCTCTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGAT
AGAGATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACC
AAAGATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGAT
GACTTGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTT
GGATATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTC
AGATCCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCT
AGTGGGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTT
GAAGCTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTA
ACTCTGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATA
ACTGCCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCC
AAGACAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTT
TGCACCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATT
GCTTTAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCA
ACGTTTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGC
TCGCAAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTT
GACACCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTT
ATTGAACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCT
GAAGATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAAC
ATTCAGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAG
CCACAAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAAC
AGAAAATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGG
GGGCTGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGAC
ATTCTCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTC
AAGAAGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCT
CTCATCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAA
AAAATGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAAC
CATCAGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGT
CGACCATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTAT
TGCCACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAG
GAATTATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTT
CTTTGCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCT
AAGAGTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCG
GGAAGGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACC
ACATTATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTA
CAATGTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAA
AGTAGAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTAT
TGGCTACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCAC
TTTCAAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTA
TTTATTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTA

>40446_40446_8_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000264107_RAPGEF4_chr2_173898642_ENST00000397081_length(amino acids)=1202AA_BP=0
LIKRLRVSREQRAHSAVASCPRGGAAGRRARPVPGVGPGAAARGGEGGCGSSSAAASDPARSAGRPLQVPAPLPVRPPMAAAGQLCLLYL
SAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDND
ADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQQGV
AATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPR
ANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGT
KDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIF
RSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQEL
TLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKF
CTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNG
SQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKS
EDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDN
RKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKF
KKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKN

--------------------------------------------------------------
>40446_40446_9_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000343713_RAPGEF4_chr2_173898641_ENST00000264111_length(transcript)=4681nt_BP=3176nt
AACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCGCGACCCGTCCCGGGGGTGGGGCCGGGCGCAG
CGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCCCGGAGCGCAGGGCGGCCGCTGCAGGTCCCCG
CTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAG
CCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGC
AACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGC
TGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATC
AGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATA
CGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGA
GCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACA
TTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGCCTGCTGTTTTTGACCAGCGTTTCCTATACAGATCCTGATCAGTTTGTTTATA
AAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGATGAATAGCTACCTAGGTTTTTCTTTGGACTCAGGGAAAGGTA
TTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCAATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGT
CTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCTCTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGG
ATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAGATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGC
AAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAGATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTA
ATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACTTGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAA
ATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGATATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACC
CTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGATCCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTC
CTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTGGGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTA
ACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAGCTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTC
AGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTCTGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGT
GGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTGCCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGA
ATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGACAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAG
ACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCACCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTC
AAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTTTAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATC
CCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGTTTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGG
CTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGCAAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAA
ATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACACCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCA
ATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTGAACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGG
TGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAGATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAA
ACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATT
TGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCACAAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACT
CAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACT
GTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGCTGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGA
ACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTCTCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATA
TCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGAAGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGA
ACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCATCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTC
ATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAATGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACA
GGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATCAGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACA
ACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGACCATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGT
CCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCCACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGAC
ACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAATTATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATC
CCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTTGCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAA
ATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGAGTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGG
ATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAAGGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATT
CTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACATTATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGAC
TGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAATGTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGA
ATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTAGAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTT
TTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGCTACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTT
AAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTCAAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTAT
TTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTATTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTT
TCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATCTTCTGTAAATAACATCTAGTATCTTCACTAAATATAATTGTC

>40446_40446_9_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000343713_RAPGEF4_chr2_173898641_ENST00000264111_length(amino acids)=1131AA_BP=1
MQVPAPLPVRPPMAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN
RTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMD
GGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFSLD
SGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYV
YMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLD
RNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGL
SSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLK
EGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAY
RELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVA
KPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLT
ESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTA
AAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTART

--------------------------------------------------------------
>40446_40446_10_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000343713_RAPGEF4_chr2_173898641_ENST00000397081_length(transcript)=4683nt_BP=3176nt
AACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCGCGACCCGTCCCGGGGGTGGGGCCGGGCGCAG
CGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCCCGGAGCGCAGGGCGGCCGCTGCAGGTCCCCG
CTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAG
CCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGC
AACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGC
TGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATC
AGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATA
CGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGA
GCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACA
TTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGCCTGCTGTTTTTGACCAGCGTTTCCTATACAGATCCTGATCAGTTTGTTTATA
AAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGATGAATAGCTACCTAGGTTTTTCTTTGGACTCAGGGAAAGGTA
TTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCAATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGT
CTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCTCTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGG
ATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAGATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGC
AAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAGATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTA
ATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACTTGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAA
ATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGATATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACC
CTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGATCCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTC
CTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTGGGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTA
ACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAGCTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTC
AGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTCTGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGT
GGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTGCCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGA
ATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGACAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAG
ACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCACCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTC
AAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTTTAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATC
CCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGTTTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGG
CTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGCAAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAA
ATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACACCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCA
ATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTGAACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGG
TGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAGATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAA
ACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATT
TGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCACAAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACT
CAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACT
GTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGCTGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGA
ACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTCTCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATA
TCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGAAGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGA
ACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCATCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTC
ATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAATGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACA
GGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATCAGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACA
ACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGACCATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGT
CCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCCACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGAC
ACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAATTATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATC
CCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTTGCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAA
ATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGAGTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGG
ATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAAGGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATT
CTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACATTATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGAC
TGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAATGTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGA
ATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTAGAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTT
TTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGCTACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTT
AAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTCAAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTAT
TTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTATTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTT
TCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATCTTCTGTAAATAACATCTAGTATCTTCACTAAATATAATTGTC

>40446_40446_10_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000343713_RAPGEF4_chr2_173898641_ENST00000397081_length(amino acids)=1131AA_BP=1
MQVPAPLPVRPPMAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN
RTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMD
GGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFSLD
SGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYV
YMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLD
RNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGL
SSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLK
EGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAY
RELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVA
KPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLT
ESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTA
AAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTART

--------------------------------------------------------------
>40446_40446_11_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000343713_RAPGEF4_chr2_173898642_ENST00000264111_length(transcript)=4681nt_BP=3176nt
AACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCGCGACCCGTCCCGGGGGTGGGGCCGGGCGCAG
CGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCCCGGAGCGCAGGGCGGCCGCTGCAGGTCCCCG
CTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAG
CCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGC
AACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGC
TGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATC
AGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATA
CGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGA
GCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACA
TTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGCCTGCTGTTTTTGACCAGCGTTTCCTATACAGATCCTGATCAGTTTGTTTATA
AAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGATGAATAGCTACCTAGGTTTTTCTTTGGACTCAGGGAAAGGTA
TTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCAATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGT
CTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCTCTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGG
ATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAGATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGC
AAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAGATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTA
ATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACTTGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAA
ATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGATATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACC
CTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGATCCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTC
CTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTGGGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTA
ACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAGCTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTC
AGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTCTGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGT
GGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTGCCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGA
ATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGACAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAG
ACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCACCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTC
AAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTTTAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATC
CCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGTTTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGG
CTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGCAAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAA
ATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACACCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCA
ATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTGAACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGG
TGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAGATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAA
ACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATT
TGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCACAAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACT
CAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACT
GTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGCTGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGA
ACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTCTCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATA
TCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGAAGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGA
ACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCATCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTC
ATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAATGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACA
GGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATCAGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACA
ACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGACCATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGT
CCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCCACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGAC
ACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAATTATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATC
CCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTTGCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAA
ATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGAGTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGG
ATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAAGGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATT
CTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACATTATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGAC
TGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAATGTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGA
ATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTAGAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTT
TTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGCTACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTT
AAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTCAAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTAT
TTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTATTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTT
TCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATCTTCTGTAAATAACATCTAGTATCTTCACTAAATATAATTGTC

>40446_40446_11_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000343713_RAPGEF4_chr2_173898642_ENST00000264111_length(amino acids)=1131AA_BP=1
MQVPAPLPVRPPMAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN
RTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMD
GGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFSLD
SGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYV
YMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLD
RNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGL
SSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLK
EGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAY
RELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVA
KPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLT
ESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTA
AAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTART

--------------------------------------------------------------
>40446_40446_12_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000343713_RAPGEF4_chr2_173898642_ENST00000397081_length(transcript)=4683nt_BP=3176nt
AACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCGCGACCCGTCCCGGGGGTGGGGCCGGGCGCAG
CGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCCCGGAGCGCAGGGCGGCCGCTGCAGGTCCCCG
CTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAG
CCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGC
AACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGC
TGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATC
AGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATA
CGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGA
GCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACA
TTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGCCTGCTGTTTTTGACCAGCGTTTCCTATACAGATCCTGATCAGTTTGTTTATA
AAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGATGAATAGCTACCTAGGTTTTTCTTTGGACTCAGGGAAAGGTA
TTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCAATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGT
CTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCTCTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGG
ATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAGATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGC
AAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAGATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTA
ATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACTTGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAA
ATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGATATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACC
CTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGATCCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTC
CTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTGGGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTA
ACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAGCTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTC
AGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTCTGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGT
GGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTGCCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGA
ATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGACAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAG
ACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCACCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTC
AAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTTTAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATC
CCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGTTTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGG
CTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGCAAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAA
ATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACACCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCA
ATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTGAACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGG
TGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAGATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAA
ACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATT
TGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCACAAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACT
CAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACT
GTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGCTGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGA
ACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTCTCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATA
TCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGAAGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGA
ACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCATCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTC
ATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAATGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACA
GGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATCAGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACA
ACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGACCATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGT
CCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCCACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGAC
ACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAATTATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATC
CCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTTGCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAA
ATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGAGTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGG
ATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAAGGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATT
CTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACATTATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGAC
TGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAATGTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGA
ATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTAGAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTT
TTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGCTACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTT
AAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTCAAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTAT
TTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTATTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTT
TCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATCTTCTGTAAATAACATCTAGTATCTTCACTAAATATAATTGTC

>40446_40446_12_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000343713_RAPGEF4_chr2_173898642_ENST00000397081_length(amino acids)=1131AA_BP=1
MQVPAPLPVRPPMAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN
RTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMD
GGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFSLD
SGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYV
YMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLD
RNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGL
SSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLK
EGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAY
RELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVA
KPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLT
ESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTA
AAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTART

--------------------------------------------------------------
>40446_40446_13_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000375221_RAPGEF4_chr2_173898641_ENST00000264111_length(transcript)=4813nt_BP=3308nt
AACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCGCGACCCGTCCCGGGGGTGGGGCCGGGCGCAG
CGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCCCGGAGCGCAGGGCGGCCGCTGCAGGTCCCCG
CTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAG
CCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGC
AACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGC
TGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATC
AGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATA
CGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGA
GCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACA
TTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAGAATAACACTTTTTTTGACATGAACATCTTTG
AAGATGGGCCTTATGAAGTTGGTGGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTTCCTGCTAACAGTTACTTAGGCCTGCTGTTTT
TGACCAGCGTTTCCTATACAGATCCTGATCAGTTTGTTTATAAAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGA
TGAATAGCTACCTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCA
ATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCT
CTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAG
ATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAG
ATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACT
TGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGAT
ATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGAT
CCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTG
GGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAG
CTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTC
TGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTG
CCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGA
CAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCA
CCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTT
TAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGT
TTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGC
AAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACA
CCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTG
AACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAG
ATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTC
AGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCAC
AAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAA
AATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGC
TGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTC
TCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGA
AGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCA
TCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAA
TGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATC
AGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGAC
CATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCC
ACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAAT
TATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTT
GCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGA
GTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAA
GGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACAT
TATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAAT
GTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTA
GAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGC
TACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTC
AAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTA
TTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATC

>40446_40446_13_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000375221_RAPGEF4_chr2_173898641_ENST00000264111_length(amino acids)=1175AA_BP=1
MQVPAPLPVRPPMAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN
RTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMD
GGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYL
GLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDG
EGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGA
PYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTAC
GAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRP
IPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQ
KDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTE
VTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTA
TLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC
PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKL
EPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRL

--------------------------------------------------------------
>40446_40446_14_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000375221_RAPGEF4_chr2_173898641_ENST00000397081_length(transcript)=4815nt_BP=3308nt
AACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCGCGACCCGTCCCGGGGGTGGGGCCGGGCGCAG
CGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCCCGGAGCGCAGGGCGGCCGCTGCAGGTCCCCG
CTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAG
CCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGC
AACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGC
TGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATC
AGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATA
CGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGA
GCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACA
TTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAGAATAACACTTTTTTTGACATGAACATCTTTG
AAGATGGGCCTTATGAAGTTGGTGGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTTCCTGCTAACAGTTACTTAGGCCTGCTGTTTT
TGACCAGCGTTTCCTATACAGATCCTGATCAGTTTGTTTATAAAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGA
TGAATAGCTACCTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCA
ATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCT
CTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAG
ATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAG
ATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACT
TGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGAT
ATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGAT
CCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTG
GGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAG
CTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTC
TGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTG
CCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGA
CAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCA
CCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTT
TAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGT
TTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGC
AAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACA
CCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTG
AACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAG
ATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTC
AGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCAC
AAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAA
AATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGC
TGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTC
TCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGA
AGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCA
TCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAA
TGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATC
AGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGAC
CATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCC
ACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAAT
TATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTT
GCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGA
GTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAA
GGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACAT
TATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAAT
GTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTA
GAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGC
TACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTC
AAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTA
TTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATC

>40446_40446_14_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000375221_RAPGEF4_chr2_173898641_ENST00000397081_length(amino acids)=1175AA_BP=1
MQVPAPLPVRPPMAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN
RTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMD
GGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYL
GLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDG
EGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGA
PYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTAC
GAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRP
IPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQ
KDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTE
VTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTA
TLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC
PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKL
EPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRL

--------------------------------------------------------------
>40446_40446_15_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000375221_RAPGEF4_chr2_173898642_ENST00000264111_length(transcript)=4813nt_BP=3308nt
AACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCGCGACCCGTCCCGGGGGTGGGGCCGGGCGCAG
CGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCCCGGAGCGCAGGGCGGCCGCTGCAGGTCCCCG
CTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAG
CCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGC
AACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGC
TGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATC
AGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATA
CGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGA
GCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACA
TTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAGAATAACACTTTTTTTGACATGAACATCTTTG
AAGATGGGCCTTATGAAGTTGGTGGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTTCCTGCTAACAGTTACTTAGGCCTGCTGTTTT
TGACCAGCGTTTCCTATACAGATCCTGATCAGTTTGTTTATAAAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGA
TGAATAGCTACCTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCA
ATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCT
CTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAG
ATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAG
ATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACT
TGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGAT
ATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGAT
CCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTG
GGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAG
CTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTC
TGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTG
CCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGA
CAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCA
CCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTT
TAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGT
TTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGC
AAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACA
CCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTG
AACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAG
ATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTC
AGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCAC
AAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAA
AATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGC
TGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTC
TCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGA
AGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCA
TCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAA
TGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATC
AGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGAC
CATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCC
ACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAAT
TATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTT
GCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGA
GTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAA
GGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACAT
TATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAAT
GTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTA
GAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGC
TACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTC
AAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTA
TTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATC

>40446_40446_15_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000375221_RAPGEF4_chr2_173898642_ENST00000264111_length(amino acids)=1175AA_BP=1
MQVPAPLPVRPPMAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN
RTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMD
GGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYL
GLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDG
EGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGA
PYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTAC
GAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRP
IPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQ
KDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTE
VTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTA
TLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC
PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKL
EPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRL

--------------------------------------------------------------
>40446_40446_16_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000375221_RAPGEF4_chr2_173898642_ENST00000397081_length(transcript)=4815nt_BP=3308nt
AACGGGCTCATTCAGCGGTCGCGAGCTGCCCGCGAGGGGGAGCGGCCGGACGGAGAGCGCGACCCGTCCCGGGGGTGGGGCCGGGCGCAG
CGGCGAGAGGAGGCGAAGGTGGCTGCGGTAGCAGCAGCGCGGCAGCCTCGGACCCAGCCCGGAGCGCAGGGCGGCCGCTGCAGGTCCCCG
CTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAG
CCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGC
AACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGC
TGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATC
AGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATA
CGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGA
GCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACA
TTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAGAATAACACTTTTTTTGACATGAACATCTTTG
AAGATGGGCCTTATGAAGTTGGTGGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTTCCTGCTAACAGTTACTTAGGCCTGCTGTTTT
TGACCAGCGTTTCCTATACAGATCCTGATCAGTTTGTTTATAAAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGA
TGAATAGCTACCTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCA
ATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCT
CTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAG
ATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAG
ATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACT
TGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGAT
ATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGAT
CCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTG
GGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAG
CTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTC
TGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTG
CCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGA
CAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCA
CCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTT
TAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGT
TTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGC
AAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACA
CCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTG
AACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAG
ATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTC
AGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCAC
AAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAA
AATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGC
TGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTC
TCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGA
AGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCA
TCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAA
TGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATC
AGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGAC
CATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCC
ACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAAT
TATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTT
GCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGA
GTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAA
GGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACAT
TATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAAT
GTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTA
GAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGC
TACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTC
AAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTA
TTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATC

>40446_40446_16_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000375221_RAPGEF4_chr2_173898642_ENST00000397081_length(amino acids)=1175AA_BP=1
MQVPAPLPVRPPMAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN
RTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMD
GGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYL
GLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDG
EGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGA
PYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTAC
GAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRP
IPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQ
KDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTE
VTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTA
TLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC
PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKL
EPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRL

--------------------------------------------------------------
>40446_40446_17_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409080_RAPGEF4_chr2_173898641_ENST00000264111_length(transcript)=4493nt_BP=2988nt
ATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAGCCTTCAACTTGGACACTCGGGAG
GACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGCAACTGCAGCCCGAGGACAAGCGG
CTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGCTGTACAGCTGCGACATCACCGCC
CGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATCAGTGGATGGGGGTCACCGTCCAG
AGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATACGAAGCAGGAATCCCGAGACATC
TTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGAGCTTTTGTGATGGGCGATTGAGA
GGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACATTGTATTTGGAGCCCCGGGTACT
TATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAGAATAACACTTTTTTTGACATGAACATCTTTGAAGATGGGCCTTATGAAGTTGGT
GGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTTCCTGCTAACAGTTACTTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCT
AAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCAATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACAT
CTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCTCTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGG
CAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAGATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGA
TGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAGATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGAT
GGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACTTGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAA
CCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGATATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTT
GCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGATCCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGA
ATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTGGGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCT
GGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAGCTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGA
AACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTCTGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAG
GATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTGCCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTT
CCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGACAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAAT
GTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCACCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGT
GTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTTTAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAA
GATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGTTTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCT
GAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGCAAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACT
TTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACACCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGAT
AATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTGAACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTT
GGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAGATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGT
AAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAA
GTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCACAAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAG
AAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTG
AACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGCTGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACA
TTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTCTCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTG
CCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGAAGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGG
GCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCATCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGG
AACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAATGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAA
CCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATCAGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGA
ACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGACCATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATC
TTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCCACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGG
GCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAATTATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTT
GTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTTGCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTT
GTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGAGTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATT
TTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAAGGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATC
TTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACATTATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGT
AATTTCTGAATGTATATAGAATAATATTTATGTTTACAATGTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACT
AAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTAGAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAAT
TGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGCTACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTA
TTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTCAAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGC
TACATAATAGATACTGTGCCAAATAATTACTTTTTATTTATTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATT

>40446_40446_17_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409080_RAPGEF4_chr2_173898641_ENST00000264111_length(amino acids)=1124AA_BP=0
MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITA
RGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR
GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVS
KDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR
WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDV
AVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFR
NQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDN
VCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFP
EKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYF
GGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK
KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRL
PNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQ

--------------------------------------------------------------
>40446_40446_18_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409080_RAPGEF4_chr2_173898641_ENST00000397081_length(transcript)=4495nt_BP=2988nt
ATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAGCCTTCAACTTGGACACTCGGGAG
GACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGCAACTGCAGCCCGAGGACAAGCGG
CTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGCTGTACAGCTGCGACATCACCGCC
CGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATCAGTGGATGGGGGTCACCGTCCAG
AGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATACGAAGCAGGAATCCCGAGACATC
TTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGAGCTTTTGTGATGGGCGATTGAGA
GGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACATTGTATTTGGAGCCCCGGGTACT
TATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAGAATAACACTTTTTTTGACATGAACATCTTTGAAGATGGGCCTTATGAAGTTGGT
GGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTTCCTGCTAACAGTTACTTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCT
AAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCAATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACAT
CTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCTCTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGG
CAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAGATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGA
TGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAGATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGAT
GGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACTTGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAA
CCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGATATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTT
GCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGATCCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGA
ATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTGGGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCT
GGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAGCTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGA
AACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTCTGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAG
GATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTGCCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTT
CCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGACAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAAT
GTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCACCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGT
GTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTTTAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAA
GATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGTTTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCT
GAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGCAAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACT
TTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACACCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGAT
AATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTGAACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTT
GGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAGATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGT
AAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAA
GTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCACAAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAG
AAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTG
AACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGCTGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACA
TTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTCTCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTG
CCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGAAGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGG
GCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCATCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGG
AACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAATGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAA
CCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATCAGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGA
ACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGACCATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATC
TTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCCACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGG
GCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAATTATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTT
GTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTTGCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTT
GTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGAGTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATT
TTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAAGGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATC
TTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACATTATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGT
AATTTCTGAATGTATATAGAATAATATTTATGTTTACAATGTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACT
AAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTAGAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAAT
TGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGCTACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTA
TTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTCAAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGC
TACATAATAGATACTGTGCCAAATAATTACTTTTTATTTATTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATT

>40446_40446_18_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409080_RAPGEF4_chr2_173898641_ENST00000397081_length(amino acids)=1124AA_BP=0
MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITA
RGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR
GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVS
KDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR
WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDV
AVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFR
NQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDN
VCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFP
EKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYF
GGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK
KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRL
PNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQ

--------------------------------------------------------------
>40446_40446_19_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409080_RAPGEF4_chr2_173898642_ENST00000264111_length(transcript)=4493nt_BP=2988nt
ATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAGCCTTCAACTTGGACACTCGGGAG
GACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGCAACTGCAGCCCGAGGACAAGCGG
CTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGCTGTACAGCTGCGACATCACCGCC
CGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATCAGTGGATGGGGGTCACCGTCCAG
AGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATACGAAGCAGGAATCCCGAGACATC
TTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGAGCTTTTGTGATGGGCGATTGAGA
GGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACATTGTATTTGGAGCCCCGGGTACT
TATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAGAATAACACTTTTTTTGACATGAACATCTTTGAAGATGGGCCTTATGAAGTTGGT
GGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTTCCTGCTAACAGTTACTTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCT
AAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCAATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACAT
CTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCTCTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGG
CAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAGATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGA
TGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAGATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGAT
GGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACTTGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAA
CCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGATATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTT
GCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGATCCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGA
ATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTGGGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCT
GGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAGCTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGA
AACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTCTGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAG
GATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTGCCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTT
CCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGACAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAAT
GTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCACCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGT
GTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTTTAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAA
GATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGTTTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCT
GAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGCAAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACT
TTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACACCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGAT
AATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTGAACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTT
GGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAGATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGT
AAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAA
GTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCACAAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAG
AAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTG
AACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGCTGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACA
TTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTCTCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTG
CCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGAAGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGG
GCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCATCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGG
AACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAATGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAA
CCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATCAGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGA
ACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGACCATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATC
TTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCCACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGG
GCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAATTATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTT
GTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTTGCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTT
GTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGAGTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATT
TTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAAGGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATC
TTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACATTATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGT
AATTTCTGAATGTATATAGAATAATATTTATGTTTACAATGTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACT
AAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTAGAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAAT
TGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGCTACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTA
TTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTCAAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGC
TACATAATAGATACTGTGCCAAATAATTACTTTTTATTTATTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATT

>40446_40446_19_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409080_RAPGEF4_chr2_173898642_ENST00000264111_length(amino acids)=1124AA_BP=0
MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITA
RGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR
GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVS
KDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR
WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDV
AVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFR
NQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDN
VCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFP
EKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYF
GGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK
KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRL
PNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQ

--------------------------------------------------------------
>40446_40446_20_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409080_RAPGEF4_chr2_173898642_ENST00000397081_length(transcript)=4495nt_BP=2988nt
ATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCCCGGCTCGGCGCAGCCTTCAACTTGGACACTCGGGAG
GACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGCAACTGCAGCCCGAGGACAAGCGG
CTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGCTGTACAGCTGCGACATCACCGCC
CGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATCAGTGGATGGGGGTCACCGTCCAG
AGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATACGAAGCAGGAATCCCGAGACATC
TTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGAGCTTTTGTGATGGGCGATTGAGA
GGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAAGACTTTCATTACATTGTATTTGGAGCCCCGGGTACT
TATAACTGGAAAGGGATTGTTCGTGTAGAGCAAAAGAATAACACTTTTTTTGACATGAACATCTTTGAAGATGGGCCTTATGAAGTTGGT
GGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTTCCTGCTAACAGTTACTTAGGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCT
AAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCAATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACAT
CTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCTCTTCATTTGGCTATGATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGG
CAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAGATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGA
TGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAGATTCTATGTTTGGCATTGCAGTAAAAAATATTGGAGATATTAATCAAGAT
GGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACTTGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAATACCAAA
CCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGATATTCAATTGCTGGAAACATGGACCTTGATCGAAATTCCTACCCTGATGTT
GCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGATCCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCTAACAGA
ATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTGGGATATGCCTCCAGGTTAAATCCTGTTTTGAATATACTGCTAACCCCGCT
GGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAGCTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGA
AACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTCTGAAGAGGCAGAAACAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAG
GATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTGCCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTT
CCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGACAGCTCATATTGATGTTCACTTCTTAAAAGAGGGATGTGGAGACGACAAT
GTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCACCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAAAAAGGT
GTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTTTAGAAATAACAGTGACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAA
GATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGTTTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCT
GAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGCAAGCTGACTGTGAGCTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACT
TTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACACCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAATCAAGAT
AATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTGAACTGCTTTTATCGGTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTT
GGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAGATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAACTTAGGT
AAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAA
GTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCACAAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAG
AAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTG
AACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGCTGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACA
TTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTCTCATGCGAGCCTTCATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTG
CCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGAAGTTCTATGCGGAGTTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGG
GCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCATCCCCTTCATGCCTTTGCTCATTAAAGATATGACATTTACTCATGAGGGG
AACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAATGCGCATGATTGCAAATACGGCCAGAACAGTGAGATACTACAGGAGCCAA
CCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATCAGGATGTCCGGAGTTATGTACGGCAATTAAATGTGATTGACAACCAGAGA
ACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGACCATAGACATTTCAAATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATC
TTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCCACTAGAGAATTCTACAAAACAAGCAAAAACACATCCTGAGACACCTCAGG
GCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAATTATTTGACATGCCTAAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTT
GTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTTGCTGAAGTGTTGAATAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTT
GTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGAGTGTTTATGGGATGAGATGTGCTACAAATGGGATAGATTTGGATAAAATT
TTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAAGGTGTTGAGGAATCTATAGAAGTCCAAATTATAGGTTGTATTCTTCCATC
TTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACATTATTATGAAACATTATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGT
AATTTCTGAATGTATATAGAATAATATTTATGTTTACAATGTAACTTTTCAAAATTTACAAATCAGGATTATATACATAAGAATTCCACT
AAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTAGAAAATAACATTTCAGAAGAGCACAATATGCATAAAACATTTTTCAAAAT
TGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGCTACAAATTTATTGTACCTGATGAAAACATATTTTCTGGACTTAAATGTTA
TTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTCAAAGATTGTAAATAGTTCATTCAATCAATGGTATGGAGTTATTTATTTGC
TACATAATAGATACTGTGCCAAATAATTACTTTTTATTTATTTTATTTAGTACGTAATTTTGAAGTACATTTTTTCCTGTTTTCACAATT

>40446_40446_20_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409080_RAPGEF4_chr2_173898642_ENST00000397081_length(amino acids)=1124AA_BP=0
MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITA
RGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR
GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVS
KDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR
WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDV
AVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFR
NQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDN
VCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFP
EKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYF
GGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK
KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRL
PNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQ

--------------------------------------------------------------
>40446_40446_21_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409532_RAPGEF4_chr2_173898641_ENST00000264111_length(transcript)=4349nt_BP=2844nt
ACGTCGTGGCTTCCGGGCAGGTACCGGGCAGCTGGAGACGCCAGAGCCGGCGGGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCA
CTGCAGAGAGCCAACAGAACGGGAGGGCTGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCT
GACCCCACGTCAGAAAGCAAGGAAGATCAGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCAC
CGATATGAAAAAAGGCAGCATGTTAATACGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATT
GAAGACGATATGGATGGGGGAGATTGGAGCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCA
GCTACTTTTACTAAAGACTTTCATTACATTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGCCTGCTGTTTTTGACCAGCGTTTCC
TATACAGATCCTGATCAGTTTGTTTATAAAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGATGAATAGCTACCTA
GGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCAATCACAGTGGAGCC
GTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCTCTTCATTTGGCTAT
GATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAGATGGAGAAGTTGGA
GGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAGATTCTATGTTTGGC
ATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACTTGGGAAAGGTTTTT
ATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGATATTCAATTGCTGGA
AACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGATCCCGGCCTGTGATT
AATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTGGGATATGCCTCCAG
GTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAGCTGAAAAAGAAAGA
AGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTCTGAAGAGGCAGAAA
CAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTGCCTCAGTGGAGATC
CAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGACAGCTCATATTGAT
GTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCACCCGAGAAGGAAAT
CAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTTTAGAAATAACAGTG
ACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGTTTCCAGACACTTTA
ACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGCAAGCTGACTGTGAG
CTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACACCCCAGATCTGGAT
ATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTGAACTGCTTTTATCG
GTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAGATGAAGTGGGAAGT
TTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAA
ATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCACAAAAGGAGATAAAC
TCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTT
GCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGCTGGACAGCAAGGCG
TCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTCTCATGCGAGCCTTC
ATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGAAGTTCTATGCGGAG
TTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCATCCCCTTCATGCCT
TTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAATGCGCATGATTGCA
AATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATCAGGATGTCCGGAGT
TATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGACCATAGACATTTCAA
ATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCCACTAGAGAATTCTA
CAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAATTATTTGACATGCCT
AAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTTGCTGAAGTGTTGAA
TAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGAGTGTTTATGGGATG
AGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAAGGTGTTGAGGAATC
TATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACATTATTATGAAACATT
ATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAATGTAACTTTTCAAAA
TTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTAGAAAATAACATTTC
AGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGCTACAAATTTATTGT
ACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTCAAAGATTGTAAATA
GTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTATTTTATTTAGTACG
TAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATCTTCTGTAAATAACA

>40446_40446_21_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409532_RAPGEF4_chr2_173898641_ENST00000264111_length(amino acids)=1058AA_BP=1
MLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIF
GRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGLLFLTSVSYTDPDQFVYKTRPPREQP
DTFPDVMMNSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIG
APQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLK
GISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSI
SIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPI
LNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAH
EAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPIT
AKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGL
EKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYS
KLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFID

--------------------------------------------------------------
>40446_40446_22_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409532_RAPGEF4_chr2_173898641_ENST00000397081_length(transcript)=4351nt_BP=2844nt
ACGTCGTGGCTTCCGGGCAGGTACCGGGCAGCTGGAGACGCCAGAGCCGGCGGGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCA
CTGCAGAGAGCCAACAGAACGGGAGGGCTGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCT
GACCCCACGTCAGAAAGCAAGGAAGATCAGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCAC
CGATATGAAAAAAGGCAGCATGTTAATACGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATT
GAAGACGATATGGATGGGGGAGATTGGAGCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCA
GCTACTTTTACTAAAGACTTTCATTACATTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGCCTGCTGTTTTTGACCAGCGTTTCC
TATACAGATCCTGATCAGTTTGTTTATAAAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGATGAATAGCTACCTA
GGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCAATCACAGTGGAGCC
GTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCTCTTCATTTGGCTAT
GATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAGATGGAGAAGTTGGA
GGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAGATTCTATGTTTGGC
ATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACTTGGGAAAGGTTTTT
ATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGATATTCAATTGCTGGA
AACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGATCCCGGCCTGTGATT
AATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTGGGATATGCCTCCAG
GTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAGCTGAAAAAGAAAGA
AGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTCTGAAGAGGCAGAAA
CAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTGCCTCAGTGGAGATC
CAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGACAGCTCATATTGAT
GTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCACCCGAGAAGGAAAT
CAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTTTAGAAATAACAGTG
ACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGTTTCCAGACACTTTA
ACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGCAAGCTGACTGTGAG
CTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACACCCCAGATCTGGAT
ATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTGAACTGCTTTTATCG
GTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAGATGAAGTGGGAAGT
TTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAA
ATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCACAAAAGGAGATAAAC
TCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTT
GCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGCTGGACAGCAAGGCG
TCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTCTCATGCGAGCCTTC
ATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGAAGTTCTATGCGGAG
TTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCATCCCCTTCATGCCT
TTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAATGCGCATGATTGCA
AATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATCAGGATGTCCGGAGT
TATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGACCATAGACATTTCAA
ATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCCACTAGAGAATTCTA
CAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAATTATTTGACATGCCT
AAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTTGCTGAAGTGTTGAA
TAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGAGTGTTTATGGGATG
AGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAAGGTGTTGAGGAATC
TATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACATTATTATGAAACATT
ATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAATGTAACTTTTCAAAA
TTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTAGAAAATAACATTTC
AGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGCTACAAATTTATTGT
ACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTCAAAGATTGTAAATA
GTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTATTTTATTTAGTACG
TAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATCTTCTGTAAATAACA

>40446_40446_22_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409532_RAPGEF4_chr2_173898641_ENST00000397081_length(amino acids)=1058AA_BP=1
MLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIF
GRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGLLFLTSVSYTDPDQFVYKTRPPREQP
DTFPDVMMNSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIG
APQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLK
GISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSI
SIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPI
LNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAH
EAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPIT
AKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGL
EKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYS
KLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFID

--------------------------------------------------------------
>40446_40446_23_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409532_RAPGEF4_chr2_173898642_ENST00000264111_length(transcript)=4349nt_BP=2844nt
ACGTCGTGGCTTCCGGGCAGGTACCGGGCAGCTGGAGACGCCAGAGCCGGCGGGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCA
CTGCAGAGAGCCAACAGAACGGGAGGGCTGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCT
GACCCCACGTCAGAAAGCAAGGAAGATCAGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCAC
CGATATGAAAAAAGGCAGCATGTTAATACGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATT
GAAGACGATATGGATGGGGGAGATTGGAGCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCA
GCTACTTTTACTAAAGACTTTCATTACATTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGCCTGCTGTTTTTGACCAGCGTTTCC
TATACAGATCCTGATCAGTTTGTTTATAAAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGATGAATAGCTACCTA
GGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCAATCACAGTGGAGCC
GTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCTCTTCATTTGGCTAT
GATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAGATGGAGAAGTTGGA
GGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAGATTCTATGTTTGGC
ATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACTTGGGAAAGGTTTTT
ATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGATATTCAATTGCTGGA
AACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGATCCCGGCCTGTGATT
AATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTGGGATATGCCTCCAG
GTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAGCTGAAAAAGAAAGA
AGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTCTGAAGAGGCAGAAA
CAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTGCCTCAGTGGAGATC
CAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGACAGCTCATATTGAT
GTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCACCCGAGAAGGAAAT
CAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTTTAGAAATAACAGTG
ACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGTTTCCAGACACTTTA
ACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGCAAGCTGACTGTGAG
CTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACACCCCAGATCTGGAT
ATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTGAACTGCTTTTATCG
GTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAGATGAAGTGGGAAGT
TTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAA
ATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCACAAAAGGAGATAAAC
TCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTT
GCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGCTGGACAGCAAGGCG
TCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTCTCATGCGAGCCTTC
ATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGAAGTTCTATGCGGAG
TTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCATCCCCTTCATGCCT
TTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAATGCGCATGATTGCA
AATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATCAGGATGTCCGGAGT
TATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGACCATAGACATTTCAA
ATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCCACTAGAGAATTCTA
CAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAATTATTTGACATGCCT
AAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTTGCTGAAGTGTTGAA
TAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGAGTGTTTATGGGATG
AGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAAGGTGTTGAGGAATC
TATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACATTATTATGAAACATT
ATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAATGTAACTTTTCAAAA
TTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTAGAAAATAACATTTC
AGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGCTACAAATTTATTGT
ACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTCAAAGATTGTAAATA
GTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTATTTTATTTAGTACG
TAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATCTTCTGTAAATAACA

>40446_40446_23_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409532_RAPGEF4_chr2_173898642_ENST00000264111_length(amino acids)=1058AA_BP=1
MLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIF
GRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGLLFLTSVSYTDPDQFVYKTRPPREQP
DTFPDVMMNSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIG
APQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLK
GISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSI
SIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPI
LNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAH
EAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPIT
AKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGL
EKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYS
KLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFID

--------------------------------------------------------------
>40446_40446_24_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409532_RAPGEF4_chr2_173898642_ENST00000397081_length(transcript)=4351nt_BP=2844nt
ACGTCGTGGCTTCCGGGCAGGTACCGGGCAGCTGGAGACGCCAGAGCCGGCGGGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCA
CTGCAGAGAGCCAACAGAACGGGAGGGCTGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAGTTTGATAACGATGCT
GACCCCACGTCAGAAAGCAAGGAAGATCAGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCAC
CGATATGAAAAAAGGCAGCATGTTAATACGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATT
GAAGACGATATGGATGGGGGAGATTGGAGCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCA
GCTACTTTTACTAAAGACTTTCATTACATTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGCCTGCTGTTTTTGACCAGCGTTTCC
TATACAGATCCTGATCAGTTTGTTTATAAAACACGGCCTCCCCGGGAGCAGCCTGACACATTCCCTGATGTGATGATGAATAGCTACCTA
GGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCTGGTGCTCCCAGAGCCAATCACAGTGGAGCC
GTGGTTTTGCTGAAGAGAGACATGAAGTCTGCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCTCTTCATTTGGCTAT
GATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCACAGTATTTTGATAGAGATGGAGAAGTTGGA
GGTGCAGTGTATGTCTACATGAACCAGCAAGGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAGATTCTATGTTTGGC
ATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGAGCTCCGTATGATGACTTGGGAAAGGTTTTT
ATCTATCATGGATCTGCAAATGGAATAAATACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGATATTCAATTGCTGGA
AACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCAGTAACTATTTTCAGATCCCGGCCTGTGATT
AATATTCAGAAAACCATCACAGTAACTCCTAACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTGGGATATGCCTCCAG
GTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATTGTGGGCACACTTGAAGCTGAAAAAGAAAGA
AGAAAATCTGGGCTATCCTCAAGAGTTCAGTTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTCTGAAGAGGCAGAAA
CAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGTCCCATTCCCATAACTGCCTCAGTGGAGATC
CAAGAGCCAAGCTCTCGTAGGCGAGTGAATTCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGACAGCTCATATTGAT
GTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTAGAATATAAATTTTGCACCCGAGAAGGAAAT
CAAGACAAATTTTCTTATTTACCAATTCAAAAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTTTAGAAATAACAGTG
ACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCTAAACTGATTGCAACGTTTCCAGACACTTTA
ACCTATTCTGCATATAGAGAACTGAGGGCTTTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGCAAGCTGACTGTGAG
CTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACTGAAGTCACCTTTGACACCCCAGATCTGGAT
ATTAATCTGAAGTTAGAAACAACAAGCAATCAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTGAACTGCTTTTATCG
GTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAAGCTATGAAATCTGAAGATGAAGTGGGAAGT
TTAATAGAGTATGAATTCAGGGTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAA
ATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCACAAAAGGAGATAAAC
TCCCTGAACCTAACGGAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTT
GCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGATGCCCGCTGCGGGGGCTGGACAGCAAGGCG
TCTCTTATTTTGCGCTCGAGGTTATGGAACAGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTCTCATGCGAGCCTTC
ATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGAAACTGCCAAGCAAGTTCAAGAAGTTCTATGCGGAG
TTTGAAAGTTTAATGGACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCATCCCCTTCATGCCT
TTGCTCATTAAAGATATGACATTTACTCATGAGGGGAACAAGACGTTCATTGACAATCTAGTAAACTTTGAAAAAATGCGCATGATTGCA
AATACGGCCAGAACAGTGAGATACTACAGGAGCCAACCCTTCAATCCTGATGCAGCTCAAGCTAATAAGAACCATCAGGATGTCCGGAGT
TATGTACGGCAATTAAATGTGATTGACAACCAGAGAACTTTATCACAGATGTCACACAGATTAGAGCCTCGTCGACCATAGACATTTCAA
ATGCCCAAAGCAACAGTTTGTCTCCAGTCCACAATCTTTCAAAAATGCCATTTATGCTACTACTGACTGTATTGCCACTAGAGAATTCTA
CAAAACAAGCAAAAACACATCCTGAGACACCTCAGGGCTGCATTCAGCTTACCAGCTACCTAGCAAGAGAAGGAATTATTTGACATGCCT
AAAGCTTACACACTCTAGCTTAGGAATCCCCAGTTTGTGGCTACCCTGTTTCATTTCCACTTGTGCCATCTTCTTTGCTGAAGTGTTGAA
TAAGGCCCACGTGAAGAGTTTGGTAGAAATAGCCTTGTCAAGAGAACTAGCAAGCCCCTGACATTTTTTTCTAAGAGTGTTTATGGGATG
AGATGTGCTACAAATGGGATAGATTTGGATAAAATTTTAACTCAACATCTTGATTTGGAGCCTGGGGTTTCGGGAAGGTGTTGAGGAATC
TATAGAAGTCCAAATTATAGGTTGTATTCTTCCATCTTCATTGTCTTACCTCTGAAGGAATAGAACCTGACCACATTATTATGAAACATT
ATGGCTGTTTATGTAATTTAGGGAGGACTGGTCTGTAATTTCTGAATGTATATAGAATAATATTTATGTTTACAATGTAACTTTTCAAAA
TTTACAAATCAGGATTATATACATAAGAATTCCACTAAGAAATGCCAAGATTCTTAAATTTGCCAGCGTTAAAGTAGAAAATAACATTTC
AGAAGAGCACAATATGCATAAAACATTTTTCAAAATTGAAATATTTTCCTGGGCATTAAAAACCTTTACTATTGGCTACAAATTTATTGT
ACCTGATGAAAACATATTTTCTGGACTTAAATGTTATTACAAATATCTTAATTTTCAGTAATTGTTTTGCACTTTCAAAGATTGTAAATA
GTTCATTCAATCAATGGTATGGAGTTATTTATTTGCTACATAATAGATACTGTGCCAAATAATTACTTTTTATTTATTTTATTTAGTACG
TAATTTTGAAGTACATTTTTTCCTGTTTTCACAATTAGACTACATTTAATGTGTAGGAATTGTATGTATGTATATCTTCTGTAAATAACA

>40446_40446_24_ITGA6-RAPGEF4_ITGA6_chr2_173356251_ENST00000409532_RAPGEF4_chr2_173898642_ENST00000397081_length(amino acids)=1058AA_BP=1
MLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIF
GRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGLLFLTSVSYTDPDQFVYKTRPPREQP
DTFPDVMMNSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIG
APQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLK
GISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSI
SIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPI
LNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAH
EAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPIT
AKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGL
EKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYS
KLNYLDILMRAFIDVTAAAENIRLPNAGTQKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFID

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ITGA6-RAPGEF4

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	ITGA6	chr2:173356251	chr2:173898641	ENST00000264106	+	24	26	1077_1083	1035.0	1131.0	HPS5
Hgene	ITGA6	chr2:173356251	chr2:173898641	ENST00000264107	+	23	26	1077_1083	996.0	1648.6666666666667	HPS5
Hgene	ITGA6	chr2:173356251	chr2:173898641	ENST00000343713	+	23	26	1077_1083	991.0	1728.3333333333333	HPS5
Hgene	ITGA6	chr2:173356251	chr2:173898641	ENST00000375221	+	24	27	1077_1083	1035.0	1772.3333333333333	HPS5
Hgene	ITGA6	chr2:173356251	chr2:173898641	ENST00000409080	+	23	25	1077_1083	996.0	1092.0	HPS5
Hgene	ITGA6	chr2:173356251	chr2:173898641	ENST00000409532	+	23	26	1077_1083	877.0	1085.3333333333333	HPS5
Hgene	ITGA6	chr2:173356251	chr2:173898642	ENST00000264106	+	24	26	1077_1083	1035.0	1131.0	HPS5
Hgene	ITGA6	chr2:173356251	chr2:173898642	ENST00000264107	+	23	26	1077_1083	996.0	1648.6666666666667	HPS5
Hgene	ITGA6	chr2:173356251	chr2:173898642	ENST00000343713	+	23	26	1077_1083	991.0	1728.3333333333333	HPS5
Hgene	ITGA6	chr2:173356251	chr2:173898642	ENST00000375221	+	24	27	1077_1083	1035.0	1772.3333333333333	HPS5
Hgene	ITGA6	chr2:173356251	chr2:173898642	ENST00000409080	+	23	25	1077_1083	996.0	1092.0	HPS5
Hgene	ITGA6	chr2:173356251	chr2:173898642	ENST00000409532	+	23	26	1077_1083	877.0	1085.3333333333333	HPS5

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for ITGA6-RAPGEF4

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for ITGA6-RAPGEF4

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source